[Hub]/) : Traits : Lung FVC : ← →

chr9:94,363,366-96,126,104

Best TWAS P=8.7e-12 · Best GWAS P=1.04e-10 conditioned to 0.0104

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	NOL8	0.09	0.04	lasso	9	0.02	2.3e-02	6.1	-5.6	2.3e-08	-0.84	0.10	0.85	FALSE
2	GTEx	Artery Tibial	NOL8	0.04	0.03	lasso	4	0.03	3.5e-03	6.2	-6.1	1.2e-09	-0.93	0.10	0.79	FALSE
3	GTEx	Brain Cerebellar Hemisphere	IPPK	0.17	0.22	lasso	13	0.16	6.8e-05	6.2	6.0	1.9e-09	0.99	0.06	0.91	FALSE
4	GTEx	Cells Transformed fibroblasts	OGN	0.03	0.03	lasso	2	0.01	3.2e-02	6.3	6.2	4.0e-10	0.90	0.09	0.86	FALSE
5	GTEx	Liver	ECM2	0.16	0.18	enet	8	0.18	7.4e-06	6.2	-6.1	9.9e-10	-0.91	0.08	0.90	FALSE
6	GTEx	Lung	NOL8	0.08	0.03	enet	15	0.04	2.3e-04	5.3	-5.3	1.4e-07	-0.82	0.17	0.81	FALSE
7	GTEx	Muscle Skeletal	OGN	0.03	0.02	enet	9	0.03	3.0e-04	5.8	5.8	8.7e-09	0.92	0.10	0.85	FALSE
8	GTEx	Nerve Tibial	OGN	0.08	0.14	lasso	9	0.12	6.3e-09	6.4	6.5	7.2e-11	0.99	0.05	0.95	FALSE
9	GTEx	Nerve Tibial	NOL8	0.10	0.02	enet	7	0.03	4.7e-03	6.0	-6.1	8.4e-10	-0.84	0.12	0.84	FALSE
10	GTEx	Pituitary	IPPK	0.16	0.07	lasso	4	0.07	8.5e-03	5.5	6.3	2.7e-10	0.90	0.07	0.68	FALSE
11	GTEx	Small Intestine Terminal Ileum	CENPP	0.29	0.11	enet	11	0.10	2.9e-03	5.9	5.2	1.9e-07	0.74	0.14	0.56	FALSE
12	GTEx	Spleen	NOL8	0.29	0.24	lasso	2	0.19	1.1e-05	6.1	-6.1	1.4e-09	-0.78	0.07	0.90	FALSE
13	GTEx	Testis	NOL8	0.19	0.24	lasso	11	0.23	1.3e-10	6.2	-6.3	2.2e-10	-0.94	0.08	0.92	FALSE
14	GTEx	Whole Blood	NOL8	0.05	0.01	enet	21	0.01	3.5e-02	6.3	-6.8	8.7e-12	-0.67	0.08	0.75	TRUE
15	NTR	Blood	CENPP	0.02	0.02	lasso	4	0.02	2.0e-07	4.0	5.4	6.3e-08	0.79	0.15	0.85	FALSE
16	NTR	Blood	IPPK	0.02	0.01	bslmm	416	0.01	9.9e-06	6.3	5.8	5.4e-09	0.83	0.08	0.92	FALSE
17	YFS	Blood	NOL8	0.06	0.09	lasso	17	0.10	1.5e-29	6.1	-5.8	6.3e-09	-0.91	0.09	0.91	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	CENPP	0.07	0.03	lasso	5	0.06	2.1e-11	-3.5	5.7	1.5e-08	0.60	0.40	0.60	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	OGN	0.02	0.02	lasso	1	0.02	2.7e-04	6.4	6.4	1.8e-10	1.00	0.02	0.97	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPP	0.21	0.04	enet	16	0.10	1.9e-06	-3.5	5.2	2.3e-07	0.51	0.23	0.31	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPP	0.06	0.02	blup	160	0.04	6.3e-05	-3.5	5.6	2.4e-08	0.61	0.32	0.44	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	OGN	0.02	0.01	blup	51	0.01	3.4e-02	6.2	6.7	2.6e-11	0.92	0.03	0.65	FALSE
23	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	OGN	0.07	0.08	lasso	1	0.06	8.0e-04	6.3	6.3	2.3e-10	0.85	0.04	0.84	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	OGN	0.07	0.12	blup	52	0.14	1.2e-15	6.3	6.6	4.5e-11	0.93	0.04	0.96	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	OMD	0.04	0.06	lasso	3	0.05	1.1e-06	6.3	6.3	2.5e-10	0.85	0.03	0.96	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CENPP	0.06	0.04	blup	160	0.05	5.6e-06	-3.5	6.2	6.2e-10	0.61	0.32	0.60	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	OGN	0.02	0.02	blup	52	0.02	2.8e-03	-5.8	6.7	2.3e-11	0.98	0.02	0.93	FALSE
28	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	OGN	0.05	0.02	blup	52	0.03	2.4e-02	-5.8	6.8	9.6e-12	0.94	0.02	0.69	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	NOL8	0.02	0.01	blup	38	0.02	7.3e-03	6.3	-6.8	1.4e-11	-0.96	0.02	0.76	FALSE