[Hub]/) : Traits : Lung FVC :

chr15:78,032,707-79,537,269

Best TWAS P=1.14e-10 · Best GWAS P=5.27e-12 conditioned to 0.0123

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous HYKK 0.08 0.01 lasso 2 0.01 3.0e-02 3.5 5.3 9.1e-08 -0.80 0.04 0.77 FALSE
2 GTEx Liver PSMA4 0.18 0.14 lasso 1 0.11 6.5e-04 -6.4 -6.4 1.5e-10 0.94 0.02 0.93 FALSE
3 YFS Blood IREB2 0.18 0.20 enet 28 0.24 4.0e-78 -6.8 5.2 1.9e-07 -0.76 0.01 0.99 FALSE
4 YFS Blood PSMA4 0.08 0.08 lasso 10 0.11 8.3e-35 -6.9 -6.0 2.1e-09 0.88 0.00 1.00 FALSE
5 The Cancer Genome Atlas Esophageal Carcinoma CHRNA3 0.24 0.15 enet 5 0.16 6.5e-06 -6.4 6.4 1.1e-10 -0.90 0.00 0.99 TRUE
6 The Cancer Genome Atlas Esophageal Carcinoma CHRNA5 0.17 0.15 lasso 4 0.14 3.1e-05 -6.4 6.3 3.9e-10 -0.93 0.00 0.98 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma CHRNA5 0.02 0.01 blup 50 0.02 2.6e-03 3.9 5.7 1.3e-08 -0.83 0.01 0.78 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMA4 0.03 0.02 blup 40 0.02 3.1e-03 4.1 -5.7 1.3e-08 0.81 0.02 0.64 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma CHRNA3 0.05 0.02 blup 44 0.02 7.6e-03 -6.4 5.5 3.4e-08 -0.86 0.00 0.98 FALSE