Best TWAS P=2.08e-10 · Best GWAS P=1.8e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ELMO3 | 0.14 | 0.04 | lasso | 3 | 0.04 | 5.6e-04 | -4.9 | -5.7 | 1.4e-08 | 0.80 | 0.20 | 0.70 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | ATP6V0D1 | 0.12 | 0.03 | lasso | 6 | 0.03 | 8.3e-03 | -5.0 | 5.3 | 8.9e-08 | -0.81 | 0.04 | 0.63 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | TSNAXIP1 | 0.09 | 0.04 | lasso | 2 | 0.04 | 1.5e-02 | -4.1 | -5.7 | 1.4e-08 | 0.59 | 0.13 | 0.24 | FALSE |
| 4 | GTEx | Lung | LRRC29 | 0.06 | 0.02 | enet | 11 | 0.03 | 4.7e-03 | -6.0 | 5.7 | 1.5e-08 | -0.90 | 0.01 | 0.93 | FALSE |
| 5 | GTEx | Muscle Skeletal | ATP6V0D1 | 0.11 | 0.03 | enet | 13 | 0.04 | 4.8e-05 | -5.7 | 6.4 | 2.1e-10 | -0.95 | 0.00 | 1.00 | TRUE |
| 6 | GTEx | Prostate | FHOD1 | 0.36 | 0.04 | lasso | 13 | 0.10 | 1.8e-03 | -5.6 | -5.6 | 2.6e-08 | 0.78 | 0.03 | 0.80 | FALSE |
| 7 | GTEx | Testis | ATP6V0D1 | 0.43 | 0.35 | enet | 12 | 0.41 | 1.9e-19 | -6.0 | 6.3 | 3.9e-10 | -0.97 | 0.00 | 1.00 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | ATP6V0D1 | 0.04 | 0.01 | enet | 5 | 0.02 | 3.2e-03 | -5.8 | 5.5 | 4.6e-08 | -0.80 | 0.01 | 0.51 | FALSE |