TWAS hub - TSNAXIP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0190	0.0110	2.6e-03	0.029	0.014	0.006	0.014	0.013	1.6e-04	0.00620	0.04900	0.0066	7.9e-03
2	GTEx	Adrenal Gland	0.1310	0.0592	1.3e-04	0.087	NA	0.085	NA	0.094	4.9e-04	NA	0.00057	NA	2.9e-04
3	GTEx	Brain Cerebellar Hemisphere	0.1700	0.0780	4.6e-04	0.047	NA	0.082	NA	0.077	2.4e-02	NA	0.00400	NA	5.1e-03
4	GTEx	Brain Frontal Cortex BA9	0.1661	0.0697	2.3e-05	0.156	NA	0.130	NA	0.168	6.2e-05	NA	0.00026	NA	3.2e-05
5	GTEx	Cells Transformed fibroblasts	0.0770	0.0410	3.4e-04	0.022	NA	0.016	NA	0.022	7.8e-03	NA	0.02000	NA	8.2e-03
6	GTEx	Esophagus Gastroesophageal Junction	0.0880	0.0600	7.5e-03	0.040	NA	-0.008	NA	0.039	1.4e-02	NA	0.80000	NA	1.5e-02
7	GTEx	Thyroid	0.0440	0.0320	6.8e-03	0.020	NA	0.010	NA	0.015	1.1e-02	NA	0.05200	NA	2.3e-02
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0335	0.0191	3.4e-03	0.010	0.017	0.020	NA	0.011	2.1e-02	0.00500	0.00240	NA	1.8e-02
9	TCGA	Brain Lower Grade Glioma	0.0312	0.0186	1.4e-03	0.018	0.018	0.019	NA	0.021	3.0e-03	0.00360	0.00280	NA	1.8e-03
10	TCGA	Pheochromocytoma and Paraganglioma	0.1040	0.0590	7.6e-04	0.090	0.081	0.059	NA	0.079	2.0e-04	0.00039	0.00220	NA	4.7e-04
11	TCGA	Rectum Adenocarcinoma	0.1510	0.0860	5.0e-03	0.102	0.092	0.116	NA	0.113	2.2e-03	0.00360	0.00120	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
HDL Cholesterol	46.0	76.7	141.6	9.2	11.6	11.9	11.6	11.0	9.3	11.9	0.0	0.0	0.0	0.0
Medication: Seretide 50 evohaler	13.9	16.0	19.3	-4.3	-4.0	-4.4	-4.2	-3.9	-3.5	-3.9	-3.7	-4.0	-4.2	-3.6
Lung FEV1/FVC ratio	11.9	60.3	106.2	10.3	6.0	5.8	7.9	7.2	10.2	5.8	7.0	7.0	9.7	6.6
Blood Red Count	11.3	109.6	141.6	11.5	9.6	11.9	11.1	11.0	8.1	9.8	11.1	10.7	11.0	8.6
Ovarian Cancer	9.5	12.6	21.5	-3.7	-3.1	-3.5	-3.8	-3.7	-3.4	-3.3	-4.6	-3.5	-3.8	-2.2
Deep venous thrombosis (DVT) (self-reported)	6.4	8.3	10.8	2.8	3.2	2.7	3.2	3.3	2.8	3.1	2.4	3.0	2.5	2.6
Fasting Glucose	5.6	6.7	13.2	-3.6	-2.6	-2.6	-2.7	-3.2	-2.2	-1.9	-2.1	-2.3	-2.7	-2.1
Primary Biliary Cirrhosis	5.6	8.0	13.2	2.4	3.6	3.4	2.9	3.6	1.8	3.1	2.1	2.9	1.6	2.7
Frequency of tenseness / restlessness in last 2 weeks	5.6	8.8	13.9	2.8	3.3	3.2	3.1	3.4	2.4	3.1	1.4	3.2	2.3	3.7
Blood clot in the leg (DVT)	5.5	7.1	9.1	2.5	3.0	2.5	3.0	3.0	2.6	2.9	2.2	2.8	2.2	2.4
Schizophrenia (2014)	5.3	11.6	19.3	4.4	3.3	3.1	3.7	3.6	3.9	2.8	2.7	3.0	3.5	3.1
Hypothyroidism (self reported)	5.0	11.5	32.8	5.7	2.3	3.3	3.2	3.3	3.3	1.6	2.2	2.2	5.1	2.8
Fluid intelligence score	4.9	10.1	12.2	-3.4	-3.1	-3.4	-3.4	-3.5	-3.1	-3.1	-2.4	-3.1	-3.0	-3.2
Intelligence (Savage-Jansen 2018)	4.7	14.4	22.9	-4.1	-4.2	-3.8	-4.1	-4.8	-3.5	-3.8	-1.6	-3.6	-2.8	-4.5
Ever unenthusiastic/disinterested for a whole week	4.5	5.5	8.9	1.6	2.4	2.9	2.6	2.2	1.8	2.6	1.7	2.6	2.1	3.0
Hair/balding pattern: Pattern 3	4.5	6.6	12.6	-0.9	-3.3	-3.1	-2.7	-3.1	-0.9	-3.6	-2.0	-3.1	-0.4	-2.7
Ever highly irritable/argumentative for 2 days	4.5	5.4	10.7	0.6	3.3	2.5	2.4	2.6	1.3	3.1	0.5	2.7	0.2	3.2
Pulse wave peak to peak time	4.4	5.2	8.2	-1.9	-2.9	-2.3	-2.6	-2.5	-1.9	-2.6	-2.0	-2.3	-1.8	-2.1
Schizophrenia (2018)	4.3	9.0	18.0	4.2	2.7	2.8	3.1	2.9	3.3	2.1	2.2	2.4	3.6	2.9
Pulse wave Arterial Stiffness index	4.3	5.0	9.4	1.4	3.1	2.2	2.5	2.5	1.8	2.8	2.1	2.3	1.3	1.9
Diabetes (mother)	4.2	5.3	15.9	2.0	2.6	2.1	2.2	1.9	2.3	2.5	-0.5	2.3	1.3	4.0
Verbal and Numeric Reasoning (VNR)	4.1	9.9	13.6	-2.9	-3.5	-3.1	-3.4	-3.6	-3.0	-3.3	-1.8	-3.4	-2.5	-3.7
Birth weight	4.1	8.9	14.0	-3.4	-2.7	-3.5	-3.2	-3.3	-2.3	-2.6	-3.7	-2.7	-3.1	-1.8
Basal cell carcinoma (self-reported)	4.0	4.7	5.9	-1.7	-2.3	-2.2	-2.4	-2.1	-2.0	-2.4	-1.5	-2.4	-2.1	-2.4
Bipolar Disorder or Schizophrenia	3.9	9.6	20.2	4.5	2.4	2.8	3.2	2.7	3.6	1.9	2.7	2.3	4.5	2.5
Heart attack/myocardial infarction (self-reported)	3.8	5.0	9.5	1.9	2.4	2.2	2.4	2.2	1.9	2.5	1.0	2.5	1.8	3.1
Lupus	3.7	5.6	7.2	2.1	2.5	2.3	2.6	2.3	2.3	2.5	2.1	2.7	2.1	2.4
Stomach or abdominal pain in last month	3.7	4.6	6.0	2.1	2.1	1.8	2.3	1.7	2.2	2.4	1.7	2.4	2.1	2.5
Irritability	3.7	6.2	8.5	2.8	2.5	2.2	2.5	2.7	2.8	2.2	1.5	2.6	2.2	2.9
Pain experienced in last month	3.7	6.2	10.0	-1.6	-2.9	-1.7	-2.8	-2.1	-2.9	-3.2	-1.8	-3.0	-1.6	-2.9
Number of full brothers	3.6	4.5	7.4	-1.9	-2.2	-2.5	-2.1	-2.7	-1.6	-1.9	-1.7	-2.3	-2.1	-2.0
Ever depressed for a whole week	3.6	4.4	6.4	1.3	2.5	2.1	2.3	1.9	2.2	2.5	2.0	2.4	1.4	2.1
Lung FVC	3.3	17.0	32.3	-4.0	-4.2	-2.6	-4.3	-3.5	-5.7	-4.3	-2.6	-4.5	-3.6	-5.0
Hypothyroidism/myxoedema (self-reported)	3.3	6.5	21.1	4.6	1.5	2.4	2.3	2.4	2.7	0.9	1.5	1.5	3.9	2.0
Suffer from ‘nerves’	3.3	5.1	11.3	2.7	1.8	2.5	2.2	1.6	2.0	1.8	0.5	2.2	2.9	3.4
Depression (Nagel 2018)	3.1	4.6	8.4	1.5	2.4	2.3	2.3	2.1	1.5	2.6	1.2	2.5	1.4	2.9
Average weekly spirits intake	3.1	3.8	6.3	-2.3	-1.7	-1.9	-2.1	-2.0	-1.8	-1.5	-2.4	-1.8	-2.5	-1.1
Medication: Atenolol	3.1	3.9	11.1	0.6	2.2	1.4	2.1	1.4	1.7	2.8	3.3	2.5	1.1	0.7
Worry (Nagel 2018)	3.0	6.4	12.6	2.2	2.4	3.0	2.6	2.2	1.7	2.6	1.0	2.8	2.7	3.5
Neuroticism (2016)	3.0	4.3	8.9	1.9	2.1	2.2	2.2	1.7	2.1	1.8	0.7	2.3	2.0	3.0
Prospective memory result	3.0	3.7	7.2	2.0	2.0	1.4	2.1	1.8	2.7	2.0	1.7	1.8	1.7	1.7
Bilateral oophorectomy (both ovaries removed)	2.9	3.3	5.3	1.9	1.9	2.2	2.0	1.6	0.9	2.1	2.3	1.9	1.6	1.1
Schizophrenia vs Biploar Disorder	2.8	3.7	8.0	2.1	2.3	1.6	2.0	2.8	2.2	1.7	1.5	1.7	1.0	1.4
Heart attack	2.8	3.6	7.3	1.6	1.9	1.9	2.0	1.8	1.7	2.0	0.8	2.1	1.6	2.7
Eye problems/disorders: None of the above	2.8	3.2	6.4	-1.8	-1.9	-2.5	-1.9	-2.1	-0.8	-1.7	-1.1	-1.8	-1.4	-2.1
Emphysema/chronic bronchitis	2.8	3.1	5.0	-2.2	-1.8	-1.8	-1.8	-2.2	-1.6	-1.4	-2.0	-1.6	-1.6	-0.8
Chronotype (morning person)	2.7	6.2	11.6	-3.0	-1.8	-3.1	-2.6	-2.3	-1.7	-1.9	-1.4	-2.3	-3.4	-3.0
Forced vital capacity (FVC)	2.7	10.2	20.8	-4.6	-2.3	-2.4	-3.1	-2.4	-4.2	-2.3	-1.3	-2.8	-4.1	-3.9
Serious illness, injury or assault of a close relative in last 2 years	2.7	3.1	8.1	-1.9	-1.2	-1.4	-1.7	-1.4	-1.9	-1.3	-2.0	-1.6	-2.8	-1.2
Illnesses of mother	2.7	3.3	5.9	-1.1	-2.2	-2.4	-1.9	-1.7	-0.8	-2.4	-1.3	-2.3	-0.8	-2.1
Mood swings	2.7	4.9	7.0	2.6	2.3	2.5	2.3	1.9	2.1	2.2	1.3	2.3	2.0	2.6
Pain type(s) experienced in last month: Hip pain	2.7	3.4	5.3	2.1	1.6	1.3	1.9	1.6	2.3	1.7	1.1	1.8	2.2	2.2
Allergy or Eczema	2.6	7.0	9.9	-2.2	-3.1	-2.4	-2.9	-2.9	-2.6	-3.0	-3.0	-2.9	-1.7	-1.8
Neuroticism (Nagel 2018)	2.5	6.0	12.6	2.3	2.6	2.6	2.6	2.3	2.2	2.5	0.6	2.6	2.2	3.5
Falls in the last year	2.5	3.3	6.9	-2.6	-1.5	-1.0	-1.8	-1.8	-2.5	-1.3	-1.5	-1.5	-2.4	-1.4
Medication: Aspirin	2.5	3.2	5.0	1.4	2.1	1.5	1.9	2.1	1.9	2.1	0.9	2.0	0.9	2.2
Respiratory disease	2.4	5.3	8.3	-1.9	-2.8	-2.2	-2.6	-2.9	-2.0	-2.6	-2.3	-2.4	-1.5	-1.8
Neuroticism	2.4	5.7	12.5	2.3	2.4	2.3	2.4	2.1	2.3	2.3	0.7	2.6	2.4	3.5
Medication: Simvastatin	2.4	3.5	6.0	1.2	2.4	1.6	2.1	1.8	1.6	2.4	1.7	2.3	0.9	1.8
Neck or shoulder pain in last month	2.4	3.4	5.8	2.1	1.9	1.1	2.0	1.6	2.4	1.8	1.3	2.0	1.6	1.9
Osteoporosis (self-reported)	2.4	2.9	6.5	-1.6	-1.8	-1.1	-1.8	-1.6	-1.9	-1.8	-2.5	-1.9	-1.2	-0.9
Medication: Blood pressure	2.4	4.6	12.2	1.2	2.3	2.2	2.3	1.6	1.6	2.7	3.5	2.5	1.2	1.0
Illnesses of father: High blood pressure	2.4	3.0	5.0	1.9	1.2	1.6	1.7	1.4	1.9	1.5	2.1	2.0	2.2	1.3
Diabetes (father)	2.3	2.8	4.6	1.6	1.8	1.8	1.8	2.1	1.2	1.8	1.6	1.8	1.3	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.1	7.6	1.6	1.9	2.1	1.7	1.8	1.2	1.8	0.2	1.9	1.2	2.8
Had other major operations	2.3	2.8	4.3	1.8	1.4	1.4	1.8	1.4	1.8	1.7	1.0	1.9	1.8	2.1
Neuroticism score	2.3	4.7	14.0	2.1	1.9	1.9	2.1	1.6	2.2	2.0	-0.1	2.3	2.2	3.7
Tense / ‘highly strung’	2.3	3.8	7.1	1.6	2.2	2.2	2.0	2.0	1.4	2.1	1.0	2.3	1.5	2.7
Asthma (self-reported)	2.3	4.5	7.4	-2.0	-2.7	-2.1	-2.3	-2.7	-1.8	-2.3	-2.0	-2.0	-1.2	-1.6
Supplements: Zinc	2.2	2.4	3.8	1.7	1.3	1.6	1.6	1.0	1.5	1.4	1.0	1.7	1.9	2.0
Hair/balding pattern: Pattern 4	2.2	5.4	21.6	-4.6	0.6	-0.3	-1.1	0.0	-2.9	0.7	0.7	-0.6	-4.5	-2.5
Forced vital capacity (FVC), Best measure	2.2	8.0	14.3	-3.8	-2.3	-2.3	-2.8	-2.2	-3.7	-2.2	-1.3	-2.7	-3.4	-3.5
Medication for cholesterol	2.2	3.3	9.9	-0.6	-2.0	-1.6	-1.9	-1.6	-1.5	-2.5	-3.1	-2.1	-0.6	-0.7
Alcohol drinker status: Previous	2.2	2.5	5.9	1.5	1.6	1.7	1.6	1.9	1.0	1.5	0.2	1.6	1.4	2.4
Prostate Cancer	2.1	3.0	8.9	-1.9	-1.0	-0.8	-1.7	-1.3	-2.3	-1.3	-3.0	-1.7	-2.0	-0.5
Average weekly red wine intake	2.1	3.1	6.5	-1.3	-1.9	-2.5	-1.8	-2.6	-0.0	-1.9	-2.4	-1.6	-0.7	-0.8
Back pain experienced in last month	2.1	3.1	4.9	1.3	2.2	1.7	1.9	2.0	1.6	2.2	1.0	1.9	1.0	2.0
Qualifications: CSEs or equivalent	2.0	2.6	8.0	2.5	0.5	0.9	1.5	1.0	2.1	0.7	1.2	1.3	2.8	1.4
Nervous feelings	2.0	3.7	8.7	2.1	1.2	2.5	1.9	1.5	0.9	1.4	0.5	1.8	2.9	2.9
Eye problems/disorders: Cataract	2.0	2.3	3.0	1.6	1.4	1.7	1.7	1.6	1.1	1.5	1.5	1.5	1.6	1.5
Myopia	2.0	2.9	10.9	2.1	0.1	1.1	1.5	0.6	2.2	0.7	2.2	1.4	3.3	1.0
Asthma	1.9	3.8	6.8	-1.7	-2.6	-1.9	-2.2	-2.5	-1.8	-2.1	-1.8	-1.9	-1.0	-1.4
Qualifications: College or University degree	1.9	6.1	15.0	-3.3	-1.9	-2.6	-2.4	-1.6	-2.3	-1.9	-0.0	-2.2	-2.9	-3.9
Chest pain or discomfort	1.9	2.7	10.1	-1.1	-1.4	-1.4	-1.4	-1.5	-1.6	-1.4	-3.2	-1.6	-1.6	0.2
Hearing aid user	1.9	2.1	3.2	-1.2	-1.6	-1.8	-1.6	-1.6	-0.9	-1.6	-1.3	-1.6	-1.3	-1.4
Number of operations (self-reported)	1.9	2.8	4.4	1.7	1.8	1.5	2.0	1.1	1.5	2.0	2.1	1.9	1.4	1.3
Age at First Birth	1.8	2.6	5.6	-1.6	-1.9	-1.6	-1.8	-1.6	-1.3	-2.0	-0.2	-1.3	-0.7	-2.4
Impedance of arm (right)	1.8	8.4	16.0	1.4	3.9	4.0	2.9	3.6	0.8	3.5	0.6	3.0	0.9	3.8
Time employed in main current job	1.8	2.1	6.1	1.4	0.8	1.4	1.5	0.9	1.2	1.2	0.9	1.4	2.5	2.0
Medication: Cholesterol lowering	1.8	2.8	4.7	1.7	1.7	1.9	1.7	1.4	1.3	1.6	0.7	1.9	1.7	2.2
Average weekly champagne plus white wine intake	1.8	2.5	5.9	2.4	1.8	1.1	1.6	1.7	2.2	1.1	1.3	1.2	1.2	1.1
Impedance of whole body	1.8	9.2	17.6	0.8	4.2	4.1	3.0	3.5	0.6	4.0	0.4	3.3	0.3	4.2
Breast Cancer	1.7	4.0	5.2	-2.3	-1.9	-2.2	-2.2	-2.2	-1.5	-1.9	-2.2	-1.9	-2.2	-1.5
Number of treatments/medications taken	1.7	3.1	5.1	1.4	2.2	1.4	1.9	1.4	2.1	2.2	1.5	2.1	0.6	1.8
Frequency of depressed mood in last 2 weeks	1.7	2.4	3.8	1.6	1.6	1.7	1.6	1.4	1.2	1.6	1.0	1.8	1.2	1.9
Impedance of arm (left)	1.7	7.9	15.2	1.3	3.7	3.9	2.8	3.4	0.7	3.5	0.5	3.0	1.0	3.8
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	4.3	0.9	1.7	0.8	1.6	1.5	2.1	1.7	1.8	1.7	1.1	1.0
Loneliness, isolation	1.7	2.3	5.7	1.4	1.6	1.4	1.5	1.3	1.8	1.5	0.1	1.7	1.1	2.4
Mother’s age at death	1.7	2.1	3.2	1.0	1.7	1.6	1.6	1.5	0.8	1.8	1.7	1.6	1.1	1.1
High cholesterol (Self-reported)	1.7	3.1	4.2	1.8	2.0	1.8	2.0	1.6	1.8	1.9	1.3	1.8	1.4	1.9
Medication: Lisinopril	1.7	2.1	5.1	-1.9	-1.0	-1.9	-1.4	-1.6	-1.0	-0.9	-0.6	-1.1	-2.3	-1.6
Blood Eosinophil Count	1.6	12.3	34.5	2.2	4.7	3.2	3.4	3.7	3.1	4.2	-0.9	3.4	0.4	5.9
Sensitivity / hurt feelings	1.6	2.7	5.7	0.7	2.1	1.4	1.8	1.8	1.1	2.4	1.2	1.9	0.6	2.0
Multivitamins +/- minerals	1.6	2.1	3.3	1.8	1.4	1.4	1.5	1.3	1.4	1.3	0.4	1.4	1.6	1.8
Impedance of leg (left)	1.6	7.6	16.6	0.3	4.1	3.6	2.7	3.2	0.7	3.7	0.7	3.0	-0.4	3.6
Alcohol intake frequency.	1.6	3.7	6.2	2.1	1.6	2.0	2.1	1.6	2.2	1.8	1.0	1.9	2.2	2.5
Knee pain experienced in last month	1.6	2.5	5.6	1.3	1.6	0.7	1.7	1.4	2.1	1.9	0.3	1.7	1.0	2.4
Ever smoked	1.6	2.9	3.7	1.9	1.7	1.6	1.8	1.7	1.8	1.4	1.3	1.6	1.9	1.7
Medication: Levothyroxine sodium	1.5	2.5	10.9	3.3	0.2	0.7	1.1	0.9	1.9	-0.2	0.2	0.3	3.0	1.2
Medication: Blood pressure	1.5	2.7	4.5	-1.8	-1.7	-1.6	-1.7	-1.9	-1.7	-1.5	-0.7	-1.4	-1.7	-2.1
Osteoarthritis (self-reported)	1.5	2.0	3.0	1.4	1.2	1.7	1.5	1.1	1.2	1.3	1.6	1.5	1.5	1.2
Crohns Disease (2017)	1.4	3.2	7.6	-2.2	-1.7	-1.5	-1.7	-1.7	-1.9	-1.6	-0.5	-1.8	-1.2	-2.8
Ulcerative Colitis (UC)	1.4	2.6	4.1	1.1	1.6	1.3	1.7	1.5	1.8	2.0	1.3	1.7	1.5	1.7
Number of incorrect matches in round	1.4	2.3	4.0	0.7	1.9	1.5	1.6	1.4	1.5	2.0	0.9	1.8	0.5	2.0
Medication: Ventolin 100micrograms inhaler	1.4	1.8	3.7	-0.4	-1.9	-1.3	-1.5	-1.6	-0.9	-1.8	-1.6	-1.5	-0.4	-0.8
Cholesterol lowering medication	1.4	2.0	3.8	0.8	1.9	0.9	1.7	1.8	1.5	1.9	1.2	1.4	0.2	1.3
Medication: Co-codamol	1.3	1.5	2.2	1.5	1.1	1.3	1.3	1.1	1.4	1.0	1.1	1.1	1.4	1.0
Qualifications: A levels/AS levels or equivalent	1.3	2.8	5.0	-2.0	-1.5	-1.2	-1.8	-1.6	-1.9	-1.7	-0.7	-1.8	-1.5	-2.2
Worry too long after embarrassment	1.3	2.1	6.1	1.2	1.4	1.2	1.4	1.3	1.0	1.5	0.0	1.7	1.6	2.5
Medication: Aspirin	1.3	1.7	2.8	1.0	1.7	1.1	1.4	1.7	1.3	1.6	0.5	1.4	0.5	1.7
Coronary Artery Disease (CAD)	1.2	1.4	4.7	-1.5	-1.5	-2.2	-1.5	-1.3	-0.4	-1.4	0.0	0.0	0.0	0.0
Trunk fat percentage	1.2	4.7	10.4	1.1	3.2	2.1	2.2	2.4	2.0	2.9	2.0	2.3	-0.1	1.5
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.5	1.1	0.9	1.2	1.3	1.5	0.4	1.1	0.8	1.2	1.1	1.6
High blood pressure (mother)	1.2	1.7	2.8	1.4	1.2	1.7	1.4	1.0	1.0	1.4	1.1	1.5	1.1	1.5
Migraine (self-reported)	1.2	1.4	5.9	0.9	0.8	1.0	1.1	0.9	1.1	1.1	2.4	1.3	1.1	-0.2
Bipolar Disorder (2018)	1.1	1.7	7.2	1.8	0.4	1.0	1.2	0.6	1.6	0.4	1.6	0.7	2.7	0.4
Hearing difficulty/problems: Yes	1.1	1.7	4.4	-0.7	-1.7	-0.7	-1.3	-2.1	-1.6	-1.6	-1.5	-1.3	-0.2	-0.6
Vitamin and mineral supplements	1.1	1.5	3.4	-1.6	-1.0	-1.3	-1.1	-1.0	-1.0	-0.8	0.3	-1.0	-1.6	-1.8
Taking other prescription medications	1.1	1.7	3.2	1.0	1.5	1.3	1.4	1.1	1.3	1.4	0.6	1.3	1.1	1.8
Hayfever, allergic rhinitis or eczema	1.1	2.3	4.3	-0.7	-2.1	-1.3	-1.6	-1.9	-1.3	-1.9	-2.0	-1.7	-0.3	-0.6
Supplements: Glucosamine	1.1	1.5	3.2	-1.7	-0.8	-1.0	-1.2	-1.2	-1.4	-0.7	-0.5	-0.9	-1.8	-1.4
Hair/balding pattern: Pattern 2	1.1	1.4	5.0	0.6	1.2	1.2	1.1	1.2	0.6	1.3	2.2	1.3	0.6	0.1
Supplements: Vitamin C	1.1	1.4	2.8	1.5	0.8	1.5	1.1	1.0	1.2	0.7	0.8	1.0	1.7	1.1
Waist Hip Ratio (WHR)	1.0	4.3	18.1	-3.9	0.4	-0.7	-1.3	-0.7	-2.3	0.4	-2.2	-0.5	-4.3	-0.2
Impedance of leg (right)	1.0	4.6	10.8	-0.5	3.3	2.8	1.8	2.5	-0.2	2.9	-0.2	2.1	-1.1	2.9
Alcohol usually taken with meals	1.0	1.6	6.1	2.5	0.5	0.8	0.9	1.1	1.6	0.1	0.9	0.5	2.2	0.6
Trunk fat-free mass	1.0	5.8	17.3	-3.3	-1.3	-3.5	-2.0	-1.4	-0.6	-1.2	1.0	-1.8	-3.2	-4.2
Father’s age at death	1.0	1.3	2.8	1.4	0.9	1.2	1.3	1.0	0.8	0.9	1.3	1.0	1.7	0.7
Trunk predicted mass	1.0	5.9	17.3	-3.3	-1.3	-3.5	-2.0	-1.4	-0.7	-1.2	1.0	-1.8	-3.2	-4.2
Comparative body size at age 10	1.0	2.7	11.5	1.0	1.8	-0.5	1.1	1.2	3.4	1.3	2.7	1.4	-0.3	-0.5
Number of children fathered	1.0	1.2	2.3	-0.8	-1.2	-0.9	-1.1	-0.9	-1.5	-1.2	-0.6	-1.2	-1.1	-1.1
Overall health rating	1.0	2.1	4.4	0.3	2.0	1.8	1.5	1.4	0.4	2.0	0.3	1.6	-0.2	2.1
Had major operations	1.0	1.2	3.0	-1.5	-0.7	-1.4	-0.9	-1.7	-0.6	-0.3	-0.4	-0.5	-1.6	-0.9
Mineral and other dietary supplements	1.0	1.4	2.6	0.9	1.1	1.5	1.2	1.6	0.3	1.2	0.9	1.1	1.0	1.4
Illnesses of father: None of the above (group 1)	1.0	1.2	2.7	-0.7	-1.0	-1.1	-1.2	-0.9	-0.9	-1.3	-0.7	-1.3	-0.8	-1.6
Depressed Affect (Nagel 2018)	0.9	2.0	5.0	1.4	1.6	1.1	1.4	1.1	1.8	1.4	-0.1	1.4	1.0	2.2
Triglycerides	0.9	1.5	3.9	-1.2	-1.6	-2.0	-1.6	-1.5	-1.1	-1.6	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.6	-0.5	-1.4	-0.9	-1.3	-1.6	-1.5	-1.4	0.0	0.0	0.0	0.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	4.9	-1.1	-0.4	-0.6	-0.9	-0.7	-0.9	-0.7	-2.2	-0.8	-1.6	0.4
Age at first live birth	0.9	1.5	4.9	-0.9	-1.3	-0.3	-1.2	-0.7	-2.2	-1.2	0.8	-0.8	-0.4	-2.2
Medication: Omeprazole	0.9	1.0	2.4	0.0	1.6	1.1	1.0	1.0	0.6	1.5	0.5	1.2	-0.5	1.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.2	-0.4	-1.4	-0.9	-1.1	-1.1	-0.6	-1.5	-0.5	-1.1	0.7	-1.4
Smoking status: Previous	0.9	1.4	6.2	1.7	0.3	1.4	1.1	0.8	0.3	0.3	0.4	0.8	2.5	1.3
Commuting to job workplace: Public transport	0.9	1.1	2.5	-1.1	-0.6	-0.3	-1.0	-0.8	-1.6	-1.0	-0.4	-1.2	-1.1	-1.5
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.5	-0.0	-1.3	-1.6	-1.0	-1.6	0.3	-1.4	-1.6	-1.0	-0.2	-0.4
Pulse rate	0.8	1.3	3.0	0.1	1.4	1.7	1.1	1.1	-0.1	1.5	0.6	1.5	-0.2	1.4
Noisy workplace	0.8	1.0	2.2	0.7	1.0	1.4	1.1	1.0	0.4	1.2	0.2	1.0	0.8	1.5
Lung cancer (father)	0.8	1.0	2.1	1.0	0.9	0.8	1.1	0.7	1.0	0.9	0.9	1.1	1.4	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.1	0.9	1.5	1.4	1.2	1.3	0.6	1.1	0.4	0.9	1.0	1.3
Birth weight of first child	0.8	1.4	6.3	0.1	-1.2	-0.6	-1.1	-0.8	-0.9	-1.7	-2.5	-1.3	0.1	-0.1
Body fat percentage	0.8	3.2	7.2	0.9	2.7	1.5	1.9	1.9	1.9	2.4	1.8	1.9	-0.4	1.1
Wheeze or whistling in the chest in last year	0.8	1.4	4.8	-1.0	-1.1	-1.6	-1.1	-1.3	-0.1	-1.2	-2.2	-1.0	-0.9	0.2
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	2.2	0.1	1.5	0.8	1.0	1.0	0.7	1.5	0.7	1.1	-0.6	0.9
Crohns Disease (2012)	0.7	1.1	3.0	-1.5	-0.8	-0.7	-1.0	-0.5	-1.4	-0.8	0.0	-1.1	-0.9	-1.7
Rheumatoid Arthritis	0.7	1.0	2.2	-0.5	-1.1	-1.5	-1.1	-1.2	-0.3	-1.1	-1.4	-0.9	-0.7	-0.4
Medication: Lansoprazole	0.7	0.8	1.8	0.6	1.0	0.2	1.0	0.9	1.3	1.0	1.2	0.9	0.3	0.4
Shortness of breath walking on level ground	0.7	0.9	2.6	-0.9	-0.5	-0.5	-0.8	-0.5	-1.2	-0.6	-1.4	-1.0	-1.6	-0.1
Medication for pain relief, constipation, heartburn	0.7	1.1	2.4	-0.4	-1.5	-0.5	-1.0	-1.2	-1.3	-1.3	0.1	-1.0	0.4	-1.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.7	-1.5	-0.6	-1.6	-0.7	-0.8	0.1	-0.2	0.1	-0.4	-1.4	-1.1
Handedness (chirality/laterality): Left-handed	0.7	0.9	1.5	-0.8	-0.8	-0.8	-1.1	-1.1	-0.8	-1.0	-1.2	-1.0	-1.0	-0.7
Arm fat-free mass (left)	0.7	3.4	11.4	-2.5	-0.7	-2.6	-1.3	-0.8	-0.2	-0.6	1.4	-1.1	-2.7	-3.4
Alzheimer’s Disease (in mother)	0.6	0.7	1.4	0.0	1.2	1.2	0.8	1.0	-0.1	1.1	0.6	0.9	0.0	0.6
Mean Putamen Volume	0.6	0.7	1.5	0.3	-0.9	-0.6	-0.6	-1.1	0.0	-1.2	-1.2	-1.0	0.6	-0.4
Pack years adult smoking proportion	0.6	1.0	3.7	-1.4	-0.2	-0.7	-0.9	-0.7	-0.8	-0.4	-1.2	-0.9	-1.9	-0.5
Average weekly fortified wine intake	0.6	0.7	1.5	-0.7	-1.2	-0.8	-0.9	-1.1	-0.4	-1.0	-0.7	-0.8	-0.1	-0.7
Fed-up feelings	0.6	1.1	4.5	1.3	0.9	0.9	1.0	0.6	1.1	0.9	-0.7	0.9	0.6	2.1
Serious illness, injury or assault to yourself	0.6	0.8	3.3	-1.8	0.0	-0.1	-0.5	-0.4	-1.2	0.2	-0.7	-0.2	-1.6	-0.2
Trunk fat mass	0.6	2.5	6.4	-0.0	2.5	0.8	1.4	1.7	1.6	2.3	2.1	1.6	-1.2	0.1
Pulse wave reflection index	0.6	0.8	1.6	0.7	1.0	0.7	1.0	0.7	0.9	1.0	1.3	0.7	1.1	0.3
Headache pain in last month	0.6	1.1	2.2	0.7	1.3	1.1	1.0	0.8	1.0	1.1	1.2	1.5	0.5	0.6
Arm fat-free mass (right)	0.6	3.2	10.0	-2.4	-0.7	-2.6	-1.3	-1.0	-0.0	-0.7	1.2	-1.1	-2.5	-3.2
Health satisfaction	0.6	0.8	1.8	-0.3	1.1	0.9	0.8	1.1	-0.0	1.3	0.0	1.0	-0.4	1.3
Medication: Ibuprofen	0.6	0.7	2.0	1.0	0.9	0.7	0.8	0.5	0.9	0.9	0.2	0.9	0.4	1.4
Heart disease (mother)	0.6	0.7	1.4	0.7	1.2	1.0	0.8	1.0	0.6	0.9	0.9	0.8	0.1	0.4
Arm predicted mass (right)	0.6	3.0	10.4	-2.3	-0.6	-2.6	-1.2	-0.7	0.1	-0.6	1.5	-1.0	-2.4	-3.2
Comparative height size at age 10	0.6	3.2	8.1	-2.3	2.8	0.3	0.8	1.9	0.3	2.4	1.6	1.2	-2.9	-0.5
Whole body fat-free mass	0.6	3.7	12.1	-2.5	-0.9	-2.9	-1.4	-0.9	-0.2	-0.8	1.3	-1.3	-2.5	-3.5
Whole body water mass	0.6	3.7	12.4	-2.4	-1.0	-2.9	-1.4	-1.0	-0.1	-0.9	1.3	-1.3	-2.4	-3.5
Basal metabolic rate	0.6	3.4	11.2	-2.5	-0.7	-2.6	-1.3	-0.8	-0.1	-0.6	1.3	-1.2	-2.6	-3.3
Heart disease (siblings)	0.6	0.7	2.5	0.1	0.9	0.4	0.9	1.1	0.4	1.2	-0.2	0.8	0.1	1.6
Arm predicted mass (left)	0.6	3.1	10.6	-2.4	-0.5	-2.4	-1.1	-0.7	-0.1	-0.4	1.6	-1.0	-2.5	-3.3
Bipolar Disorder (2011)	0.5	0.5	5.4	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.5	4.1	14.3	3.2	-0.2	-0.5	1.4	0.5	3.5	-0.2	2.5	0.5	3.8	0.4
Waist circumference	0.5	1.9	9.4	-2.1	0.2	-1.3	-0.9	-0.5	-0.4	0.1	0.2	-0.7	-3.1	-1.8
Financial difficulties in last 2 years	0.5	0.7	1.3	-0.3	1.1	0.1	0.7	0.8	0.9	1.2	1.0	1.0	-1.1	0.4
Alcohol intake versus 10 years previously	0.5	0.7	4.0	-1.6	0.6	-0.2	-0.2	-0.0	-0.7	0.6	-0.1	0.1	-2.0	-0.4
Happiness	0.5	0.6	2.9	-1.4	0.1	-0.6	-0.5	0.1	-0.3	-0.0	-0.1	-0.4	-1.7	-0.7
Standing height	0.5	5.1	20.4	-4.3	1.7	-1.6	-0.4	1.1	-0.7	1.6	1.4	0.2	-4.5	-2.2
Whole body fat mass	0.5	2.1	4.8	0.1	2.2	0.5	1.2	1.5	1.7	2.0	2.0	1.4	-1.1	-0.0
Pulse rate, automated reading	0.5	1.5	5.1	-0.1	1.2	2.3	0.9	0.9	-1.1	1.3	-0.2	1.4	0.2	1.7
Medication: Gliclazide	0.5	0.5	1.2	1.1	0.4	0.6	0.7	0.5	1.0	0.4	0.1	0.5	1.1	0.7
Wears glasses or contact lenses	0.5	0.5	1.1	0.3	0.8	0.7	0.8	0.5	0.5	1.0	1.0	1.1	0.2	0.7
Eye problems/disorders: Glaucoma	0.5	0.6	1.8	-0.1	1.0	1.3	0.7	0.5	-0.4	0.9	1.0	0.9	-0.1	0.4
Medication: Bendroflumethiazide	0.5	0.7	2.1	-1.1	0.4	0.2	-0.1	-0.4	-0.9	0.5	1.4	0.2	-1.1	-1.4
Alcohol drinker status: Never	0.5	0.6	2.3	0.5	0.3	0.2	0.9	0.2	1.1	0.8	-0.1	0.9	0.9	1.5
Leg fat percentage (left)	0.5	1.7	3.8	0.6	1.9	0.9	1.3	1.1	1.7	1.7	1.4	1.3	-0.7	0.7
Average weekly beer plus cider intake	0.5	0.7	2.4	-1.2	-0.3	-0.7	-0.7	-0.8	-0.9	-0.3	-1.1	-0.5	-1.6	-0.2
Diastolic blood pressure, automated reading	0.5	1.6	9.0	0.7	1.0	1.2	1.1	0.7	0.6	1.2	3.0	1.1	0.9	-0.5
Commuting to job workplace: Cycle	0.5	0.6	1.3	0.3	0.5	0.2	0.7	0.4	1.0	0.8	1.1	1.1	0.9	0.5
Pack years of smoking	0.5	0.7	3.1	-1.3	-0.1	-0.6	-0.7	-0.7	-0.6	-0.2	-0.9	-0.7	-1.8	-0.5
Alzheimer’s Disease (in father)	0.4	0.4	1.6	1.3	0.1	0.2	0.3	-0.1	0.6	0.0	-0.2	0.5	1.2	0.8
Alzheimer’s Disease (including proxy)	0.4	0.6	1.2	0.6	1.0	0.9	0.7	0.7	0.2	0.9	-0.0	0.9	0.6	1.1
Major Depression (MDD)	0.4	0.5	2.5	0.3	0.4	0.9	0.4	0.3	-0.7	0.5	1.6	0.3	0.4	-0.9
Hair Pigment	0.4	12.7	19.9	4.0	2.7	4.0	3.7	2.4	3.5	3.2	4.4	3.5	4.5	2.7
Systolic blood pressure, automated reading	0.4	1.2	3.8	-0.7	-1.3	-1.2	-0.9	-1.4	-0.6	-0.9	0.9	-0.8	-0.1	-1.9
Leg fat-free mass (left)	0.4	2.2	8.0	-1.8	-0.8	-2.3	-1.1	-0.8	0.0	-0.7	1.1	-1.0	-1.8	-2.8
Townsend deprivation index at recruitment	0.4	0.6	2.7	-0.4	-0.7	-0.2	-0.6	-0.4	-0.9	-0.8	-1.6	-0.8	-0.4	0.4
Current tobacco smoking	0.4	0.7	3.6	-0.9	0.5	-1.1	-0.5	-0.2	0.7	-0.0	-0.6	-0.3	-1.9	-0.6
Leg predicted mass (left)	0.4	2.1	7.5	-1.8	-0.7	-2.2	-1.1	-0.7	0.0	-0.6	1.1	-0.9	-1.8	-2.7
Past tobacco smoking	0.4	0.8	2.3	-1.1	-0.7	-1.0	-0.9	-0.8	-0.6	-0.5	-0.2	-0.7	-1.5	-1.1
Had menopause	0.4	0.4	1.3	0.1	0.8	0.5	0.8	0.3	0.5	0.9	0.2	0.8	0.3	1.2
Allergy	0.4	1.0	2.4	0.3	1.6	0.8	0.9	1.3	0.6	1.2	1.4	1.0	-0.4	0.0
Pain all over the body in last month	0.4	0.4	1.0	0.5	0.9	0.1	0.7	0.5	0.7	0.7	-0.1	0.8	0.3	1.0
Number of live births	0.4	0.6	2.6	1.3	0.8	-0.3	0.6	0.3	1.6	0.4	-0.3	0.4	0.4	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	0.4	0.9	0.5	0.7	0.7	0.5	0.9	0.2	0.7	-0.2	1.0
Breastfed as a baby	0.4	0.5	0.9	0.4	-0.9	-0.6	-0.6	-0.8	-0.6	-1.0	-0.3	-0.8	0.6	-0.9
Gout (self-reported)	0.4	0.6	3.2	0.7	-0.7	-0.2	-0.3	-0.1	-0.2	-0.7	-1.8	-0.5	0.6	0.9
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.0	1.1	-0.3	-0.1	0.1	-0.1	1.0	-0.2	-0.9	0.1	0.6	1.4
Medication: Allopurinol	0.4	0.6	3.2	-0.1	-0.7	-0.6	-0.6	-0.6	-0.4	-0.8	-1.8	-0.7	-0.0	0.4
Mean time to correctly identify matches	0.4	0.7	2.1	0.1	0.6	0.8	0.9	0.3	0.6	1.0	1.4	1.1	0.9	0.5
Illnesses of siblings: Diabetes	0.4	0.5	1.5	-0.1	-0.8	-0.7	-0.6	-1.0	-0.3	-0.6	-1.2	-0.5	-0.5	0.5
Qualifications: nursing, teaching	0.4	0.7	1.6	1.3	0.3	0.8	0.7	0.8	0.8	0.3	1.0	0.8	1.2	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.4	-0.8	-0.2	-0.4	-0.5	-0.4	-0.3	-0.2	-1.6	-0.3	-0.8	0.7
Smoking status: Current	0.4	0.6	3.3	-0.8	0.4	-1.1	-0.6	-0.3	0.5	-0.2	-0.8	-0.4	-1.8	-0.6
Leg fat mass (left)	0.4	1.5	3.9	-0.1	1.6	0.1	0.9	1.0	1.6	1.5	2.0	1.0	-1.2	-0.5
Ulcerative Colitis	0.3	0.5	1.0	0.2	0.8	0.5	0.6	0.4	0.9	1.0	0.3	0.8	0.6	1.0
Height	0.3	6.1	26.1	-4.6	2.2	-1.6	-0.4	1.4	-0.5	1.9	1.3	0.5	-5.1	-2.0
Smoking Status	0.3	0.8	1.5	1.0	1.1	0.7	0.9	1.0	1.2	0.7	0.3	0.9	0.7	0.9
Medication for hormone replacement therapy	0.3	0.3	1.0	-0.2	0.5	0.7	0.4	0.3	-0.2	0.8	1.0	0.7	0.1	0.1
Severe depression (siblings)	0.3	0.4	1.3	0.6	0.5	-0.1	0.4	0.4	1.1	0.3	-0.6	0.3	0.3	1.1
Age when periods started (menarche)	0.3	0.6	2.4	0.2	0.7	0.8	0.8	0.6	0.6	0.9	1.6	0.8	0.9	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.6	0.7	-0.4	-1.4	0.2	-0.1	1.6	-0.2	0.9	-0.1	0.9	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.5	0.4	-0.6	-1.6	0.1	-0.5	1.5	-0.3	0.6	-0.2	0.9	-0.3
Qualifications: None of the above	0.3	0.7	2.9	0.2	1.1	0.7	0.8	0.3	0.4	1.2	-0.7	0.7	-0.4	1.7
Weight	0.3	1.5	5.3	-1.5	0.4	-1.5	-0.4	-0.0	0.5	0.3	1.4	-0.3	-2.3	-2.1
Arm fat percentage (right)	0.3	1.2	2.7	1.1	1.4	0.7	1.1	1.1	1.6	1.2	1.5	0.9	-0.0	0.2
Worrier / anxious feelings	0.3	0.7	2.3	0.6	0.9	1.0	0.7	0.7	0.3	0.7	-0.3	0.7	0.7	1.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	2.6	0.3	0.9	0.5	0.6	0.4	0.4	0.8	-0.9	0.5	0.1	1.6
Depression (self-reported)	0.3	0.3	1.0	0.1	0.7	0.3	0.6	0.5	0.5	0.9	-0.1	0.5	0.3	1.0
Peak expiratory flow (PEF)	0.3	0.8	4.5	0.7	0.2	0.6	0.6	1.1	-0.1	0.3	2.1	0.5	0.7	-0.8
Glaucoma (self-reported)	0.3	0.3	1.0	-0.7	0.4	0.8	0.0	-0.2	-1.0	0.3	0.5	0.2	-0.7	-0.4
Exposure to tobacco smoke outside home	0.3	0.4	1.2	0.2	0.6	0.8	0.5	0.3	0.8	0.5	-0.1	0.5	0.3	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.6	-0.5	-0.8	-0.7	-0.7	-0.7	-0.4	-0.7	-0.3	-0.5	-0.5	-0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	0.4	0.2	-0.2	0.3	0.4	1.4	-0.0	-0.3	0.2	0.9	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.1	0.7	-0.6	-0.5	-0.1	-0.6	0.8	-0.6	0.1	-0.2	1.1	-0.0
Leg fat mass (right)	0.3	1.1	2.5	-0.5	1.4	-0.2	0.6	0.7	1.2	1.2	1.6	0.7	-1.6	-0.7
Number of full sisters	0.3	0.4	1.6	-1.0	0.1	-0.3	-0.2	-0.4	-0.9	0.2	-0.5	-0.1	-1.3	-0.1
Age at last live birth	0.3	0.4	1.3	-0.1	0.6	0.8	0.2	0.6	-0.8	0.6	1.1	0.8	-0.2	-0.4
Family relationship satisfaction	0.3	0.4	1.9	-1.2	0.7	-0.3	-0.0	0.6	-0.1	0.5	0.0	0.2	-1.4	-0.1
Leg pain on walking	0.3	0.3	1.7	-1.0	0.2	-0.2	-0.2	-0.1	-0.3	0.1	-0.7	-0.1	-1.3	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.0	-1.0	-0.4	-0.9	-0.5	-0.4	-0.5	-0.2	-0.3	-0.4	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.2	-1.0	-0.2	-1.0	-0.7	-0.1	-0.0	-0.4	-0.2	-0.5	-1.5	-1.1
Leg fat-free mass (right)	0.3	1.9	6.8	-1.5	-0.8	-2.2	-0.9	-0.7	0.3	-0.6	1.2	-0.8	-1.4	-2.6
Arm fat percentage (left)	0.3	1.2	2.9	1.0	1.4	0.6	1.1	1.1	1.7	1.3	1.4	1.0	-0.1	0.2
Diabetes diagnosed by doctor	0.3	0.4	0.9	0.3	0.9	0.7	0.6	0.9	0.4	0.7	-0.2	0.7	-0.2	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.0	-0.2	1.0	0.5	0.6	0.4	0.3	0.9	0.7	0.8	0.0	0.3
Leg predicted mass (right)	0.3	1.8	6.8	-1.5	-0.7	-2.1	-0.9	-0.7	0.3	-0.5	1.3	-0.8	-1.4	-2.6
Guilty feelings	0.3	0.4	1.7	-0.1	0.4	-0.5	0.3	-0.5	1.0	0.7	-0.7	0.8	-0.1	1.3
Ever taken oral contraceptive pill	0.3	0.3	1.0	-0.1	-0.6	-0.8	-0.5	-1.0	0.2	-0.5	-1.0	-0.4	0.2	0.3
Age started oral contraceptive pill	0.3	0.4	0.8	-0.3	-0.9	-0.6	-0.5	-0.9	-0.3	-0.7	0.1	-0.6	0.2	-0.8
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.2	-0.0	-1.0	-0.9	-0.9	-0.5	-0.3	-1.4	-1.5	-1.2	0.1	-0.3
Reaction Time	0.2	0.4	1.7	-0.4	0.6	0.7	0.6	0.4	0.0	0.8	1.3	0.9	0.2	0.1
HbA1C	0.2	0.3	0.4	-0.5	-0.5	-0.5	-0.5	-0.3	-0.7	-0.6	-0.4	-0.4	-0.5	-0.6
Blood White Count	0.2	1.8	8.2	-1.9	1.1	0.6	-0.5	-0.2	-2.1	0.7	-1.2	-0.0	-2.9	0.2
Systolic Blood Pressure	0.2	1.1	3.6	-0.7	-1.3	-1.1	-0.8	-1.3	-0.4	-0.9	0.9	-0.8	-0.6	-1.9
Cardiovascular Disease	0.2	0.7	3.0	-0.2	1.0	0.5	0.6	0.2	0.3	1.2	1.7	1.0	-0.7	-0.4
Relative age of first facial hair	0.2	0.5	1.6	-0.6	-0.7	-0.3	-0.7	-0.3	-1.2	-0.5	-0.3	-0.4	-1.0	-0.6
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	0.0	0.8	0.6	0.5	0.2	0.0	0.7	0.6	0.3	0.3	-0.0
Relative age voice broke	0.2	0.3	0.9	-0.2	-0.8	-0.3	-0.5	-0.6	-0.7	-0.6	0.4	-0.5	0.0	-1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.7	0.0	-0.3	-0.3	-0.1	-0.6	0.6	-0.1	-0.7	0.1	-0.0	0.9
Sitting height	0.2	1.7	8.4	-1.2	1.0	0.0	0.5	1.6	-0.5	1.0	2.9	0.4	-0.9	-1.8
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.2	-0.0	-0.1	-0.4	0.1	-0.7	-0.3	-0.7	-0.4	-0.9	-0.1
Mouth/teeth dental problems	0.2	0.4	1.1	-0.2	0.5	0.5	0.3	0.5	-0.7	0.6	1.1	0.4	-0.7	-0.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	2.3	-0.8	-0.2	-0.2	-0.4	0.1	-0.9	-0.3	1.0	-0.3	-0.7	-1.5
Mouth/teeth dental problems: Dentures	0.2	0.4	2.6	0.1	-0.1	0.1	-0.2	-0.6	-0.1	-0.2	-1.6	-0.3	-0.1	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.5	-0.9	-0.7	-0.7	-0.7	-0.4	-0.9	-0.7	0.5	-0.7	-0.8	-1.6
Arm fat mass (right)	0.2	0.9	3.4	0.1	1.1	-0.1	0.6	0.7	1.3	1.0	1.8	0.5	-1.0	-0.9
Length of working week for main job	0.2	0.2	0.5	-0.0	0.6	0.6	0.3	0.6	-0.2	0.5	-0.4	0.4	-0.4	0.7
Exposure to tobacco smoke at home	0.2	0.2	1.0	0.0	-0.3	-0.1	-0.2	-0.4	0.2	-0.3	-1.0	-0.1	0.1	0.7
Medication: Paracetamol	0.2	0.4	1.5	-0.8	0.9	-0.1	0.1	0.4	0.4	0.6	-0.4	0.2	-1.2	0.2
Medication: Amlodipine	0.2	0.3	1.2	0.1	-1.1	0.1	-0.2	-0.6	-0.4	-0.6	-0.1	-0.0	1.1	0.2
High blood pressure (siblings)	0.2	0.3	0.8	-0.3	-0.5	-0.1	-0.5	0.0	-0.9	-0.5	0.2	-0.6	-0.7	-0.9
Leg fat percentage (right)	0.2	0.8	2.2	0.1	1.5	0.5	0.8	0.7	1.1	1.2	0.7	0.8	-1.1	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.6	-0.5	-0.8	-0.7	-0.5	-0.8	-0.5	-0.3	-0.3	-0.3	-0.5	-0.1
Friendships satisfaction	0.2	0.3	1.3	-1.1	0.0	-0.4	-0.2	0.4	-0.1	0.0	0.3	-0.2	-1.0	-0.5
Commuting to job workplace: Walk	0.2	0.2	0.9	-0.0	-0.3	-0.4	-0.5	-0.2	-0.2	-0.7	-0.1	-0.6	-0.3	-1.0
Breast cancer (self-reported)	0.2	0.3	0.9	0.7	-0.2	0.2	0.3	0.2	0.2	0.0	-0.6	0.2	1.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.2	1.1	0.4	1.1	0.6	0.6	0.0	0.2	0.8	0.3	1.0	0.1
Arm fat mass (left)	0.2	1.0	3.4	0.0	1.2	-0.1	0.6	0.8	1.3	1.1	1.9	0.6	-1.0	-0.8
Number of self-reported non-cancer illnesses	0.2	0.4	1.3	-0.2	0.6	0.5	0.7	0.2	0.4	1.2	0.6	0.8	0.1	1.0
Miserableness	0.2	0.4	2.0	0.7	0.5	0.3	0.3	0.3	0.6	0.3	-0.8	0.5	0.3	1.4
Financial situation satisfaction	0.2	0.3	0.9	-0.7	0.5	-0.3	0.1	0.4	0.4	0.6	-0.0	0.4	-1.0	0.4
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.6	0.4	-0.7	-0.1	-0.5	-0.5	-0.3	-0.8	-0.4	-0.4	0.4	-0.1
Medication: Atorvastatin	0.2	0.2	0.9	-0.2	0.7	0.4	0.2	1.0	-0.1	0.5	-0.5	0.2	-0.3	0.5
Risk taking	0.2	0.3	1.6	-0.8	0.2	-0.4	-0.3	-0.1	-0.4	-0.0	-0.0	-0.3	-1.3	-0.7
Fractured/broken bones in last 5 years	0.2	0.2	0.6	-0.7	0.6	0.6	0.4	0.2	-0.3	0.8	0.3	0.4	-0.3	0.2
Supplements: Calcium	0.2	0.2	0.5	-0.1	-0.3	0.5	-0.2	-0.6	-0.7	-0.3	-0.5	-0.2	0.6	0.2
Irritable Bowel Disease (IBD)	0.1	0.1	0.8	-0.9	-0.1	-0.2	-0.1	-0.3	-0.1	0.2	0.3	-0.1	0.1	-0.6
Body Mass Index (BMI) (2010)	0.1	0.1	0.5	0.6	-0.4	-0.4	-0.3	-0.1	-0.3	-0.7	0.0	0.0	0.0	0.0
LDL Cholesterol	0.1	0.2	0.8	0.4	0.5	0.9	0.7	0.3	0.1	0.8	0.0	0.0	0.0	0.0
Blood Platelet Count	0.1	0.9	3.9	-1.2	1.3	0.2	0.2	0.3	-0.7	1.2	0.3	0.6	-2.0	-0.0
BMI	0.1	0.9	3.5	0.8	-0.4	-0.7	-0.1	-0.5	1.1	-0.5	1.7	-0.4	0.2	-1.9
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	-0.3	0.3	-0.0	-0.1	0.3	-0.2	0.0	-0.8	0.1	-0.8	0.3
Tanning	0.1	1.4	3.7	0.9	1.5	0.1	1.2	1.2	1.9	1.4	0.7	1.3	0.4	1.1
Hand grip strength (left)	0.1	0.2	0.5	-0.0	-0.2	-0.7	-0.4	0.0	0.1	-0.4	-0.4	-0.6	-0.5	-0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	-0.3	0.2	0.6	0.2	-0.0	-0.5	0.3	0.5	0.2	0.0	-0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	-0.2	0.7	0.3	0.3	0.0	-0.3	0.6	0.3	0.1	-0.3	0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.4	-0.0	-0.2	0.2	-0.3	0.1	-0.5	-0.4	-0.6	-0.3	-0.3	0.0
Angina	0.1	0.1	0.4	-0.1	0.2	-0.2	0.1	-0.1	-0.2	0.2	-0.6	0.1	-0.1	0.4
Medication: Metformin	0.1	0.2	0.7	0.2	-0.3	-0.3	-0.4	-0.3	0.1	-0.6	-0.8	-0.4	-0.0	-0.1
Maternal smoking around birth	0.1	0.2	0.5	-0.7	0.3	-0.1	0.0	0.1	0.2	0.5	0.4	0.4	-0.6	-0.1
High blood pressure	0.1	0.3	1.5	-0.4	0.3	0.2	0.3	-0.1	-0.1	0.8	1.2	0.6	-0.6	-0.4
Body mass index (BMI)	0.1	0.4	1.4	0.5	-0.3	-0.7	-0.1	-0.4	1.0	-0.3	1.0	-0.3	-0.2	-1.2
Hearing difficulty/problems with background noise	0.1	0.2	0.8	-0.2	0.1	0.9	0.4	-0.5	-0.4	0.4	0.6	0.4	0.6	0.4
Medication: Ramipril	0.1	0.2	1.1	-0.1	0.2	0.3	-0.2	-0.2	-0.4	-0.1	-1.1	-0.2	-0.3	0.3
Illnesses of siblings	0.1	0.2	1.0	0.6	0.1	0.2	0.2	0.0	0.6	-0.0	0.1	0.3	1.0	0.1
Hip circumference	0.1	0.6	2.0	-0.6	-0.1	-1.1	-0.4	-0.2	0.5	-0.2	0.5	-0.6	-1.2	-1.4
Loud music exposure frequency	0.1	0.1	0.2	-0.2	-0.1	0.2	-0.3	0.1	-0.4	-0.2	-0.1	-0.2	-0.5	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.6	-0.1	-0.5	-0.2	-0.5	-0.2	-0.6	-0.8	-0.1	-0.6	0.2	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	-0.3	0.3	0.4	0.1	-0.1	-0.3	0.2	-0.4	0.1	-0.0	0.5
Angina (self-reported)	0.1	0.1	0.5	-0.1	0.0	-0.3	-0.1	-0.3	-0.2	-0.0	-0.7	-0.0	-0.1	0.3
Hypertension (Self-reported)	0.1	0.4	2.3	-0.2	0.3	0.3	0.4	-0.2	0.0	0.8	1.5	0.7	-0.3	-0.4
Illnesses of father: Heart disease	0.1	0.1	0.3	-0.2	0.2	0.1	0.3	0.1	0.6	0.5	0.5	0.5	-0.0	0.6
Long-standing illness, disability or infirmity	0.1	0.1	0.3	-0.6	0.2	0.2	0.2	0.1	-0.0	0.4	0.2	0.4	-0.0	0.2
Ever had bowel cancer screening	0.1	0.2	0.4	-0.5	-0.4	-0.7	-0.2	-0.6	0.5	0.0	-0.2	-0.2	0.2	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	0.3	-0.5	-0.3	-0.5	-0.3	-0.2	-0.8	-0.1	-0.7	0.1	-0.8
Medication: Paracetamol	0.1	0.2	0.3	-0.4	0.5	-0.2	0.2	0.1	0.5	0.4	-0.6	0.3	-0.6	0.6
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.5	0.2	-0.5	-0.3	-0.2	-0.5	0.2	-0.5	-0.4	-0.3	0.7	0.2
Unable to work because of sickness or disability	0.1	0.2	0.5	-0.7	-0.4	-0.6	-0.3	-0.7	-0.0	-0.2	-0.6	-0.1	-0.3	0.2
Hand grip strength (right)	0.0	0.1	0.4	0.5	0.1	0.0	0.2	0.7	0.6	0.1	0.3	-0.0	0.3	-0.1
Diabetes (self-reported)	0.0	0.1	0.3	-0.1	0.4	0.3	0.2	0.5	0.0	0.2	-0.1	0.3	-0.3	0.2
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.3	0.2	0.1	0.1	0.2	0.6	0.0	0.1	0.0	-0.2	0.1	0.2

Hub : Genes

TSNAXIP1

Models

Trait associations