Best TWAS P=3.34e-10 · Best GWAS P=5.01e-20 conditioned to 3.39e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | RBBP8 | 0.07 | 0.00 | blup | 352 | 0.02 | 0.00059 | -1.4 | -6.3 | 3.3e-10 | -0.29 | 0.07 | 0.05 | TRUE |
2 | CommonMind | Brain Pre-frontal Cortex | RIOK3 | 0.02 | 0.01 | bslmm | 348 | 0.00 | 0.18300 | 4.3 | 5.9 | 4.7e-09 | 0.42 | 0.14 | 0.06 | FALSE |
3 | GTEx | Brain Cerebellar Hemisphere | RBBP8 | 0.22 | 0.16 | enet | 20 | 0.13 | 0.00030 | 4.5 | -5.3 | 1.5e-07 | -0.34 | 0.17 | 0.07 | FALSE |
4 | GTEx | Testis | C18orf8 | 0.12 | 0.07 | lasso | 6 | 0.08 | 0.00019 | 3.8 | 6.1 | 8.5e-10 | 0.42 | 0.17 | 0.47 | TRUE |