TWAS hub - KIAA0802

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0628	0.0197	1.4e-07	0.036	0.042	0.043	NA	0.045	5.5e-08	3.9e-09	3.1e-09	NA	1.6e-09
2	TCGA	Prostate Adenocarcinoma	0.1180	0.0375	9.7e-06	0.021	0.056	0.077	NA	0.077	2.4e-03	1.7e-06	1.8e-08	NA	2.0e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Lung FEV1/FVC ratio	7.5	38.1	46.7	-6.8	-5.4
Pain all over the body in last month	7.1	7.6	14.8	-3.8	-0.7
Migraine (self-reported)	5.2	6.5	8.4	2.1	2.9
Blood clot in the leg (DVT)	4.9	6.4	6.7	-2.6	-2.5
Townsend deprivation index at recruitment	4.5	6.3	8.9	-3.0	-1.9
Deep venous thrombosis (DVT) (self-reported)	4.0	5.1	5.3	-2.2	-2.3
Fed-up feelings	3.5	6.3	7.8	-2.2	-2.8
Commuting to job workplace: Walk	3.5	3.8	4.0	-2.0	-1.9
Respiratory disease	3.4	7.7	10.5	2.2	3.2
Lung FVC	3.4	17.3	33.6	-5.8	-1.0
Ever used hormone-replacement therapy (HRT)	3.4	4.4	6.3	-2.5	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	3.3	10.5	20.7	-4.5	0.7
Alzheimer’s Disease (in father)	3.2	3.4	5.0	2.2	1.4
Hayfever/allergic rhinitis (self-reported)	3.1	4.1	7.3	1.0	2.7
Bipolar Disorder (2011)	2.7	2.6	4.7	-0.7	-2.2
Forced expiratory volume in 1-second (FEV1)	2.7	9.1	18.2	-4.3	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.8	10.2	-3.2	-1.2
Pack years of smoking	2.7	3.9	4.2	-2.0	-1.9
Supplements: Vitamin C	2.6	3.0	3.5	1.6	-1.9
Financial situation satisfaction	2.6	3.3	6.1	-0.7	-2.5
Number of operations (self-reported)	2.6	3.9	5.4	-2.3	-1.5
Risk taking	2.6	3.8	7.3	-2.7	0.5
Average weekly beer plus cider intake	2.5	3.7	7.4	-2.7	-0.1
Fasting Glucose	2.4	2.9	5.7	-2.4	-0.4
Diverticular disease/diverticulitis (self-reported)	2.4	2.8	2.9	-1.7	-1.7
Average weekly spirits intake	2.3	2.8	5.2	-0.6	-2.3
Pack years adult smoking proportion	2.3	3.6	4.7	-1.5	-2.2
Medication: Levothyroxine sodium	2.3	3.9	7.8	-2.8	-0.0
Asthma (self-reported)	2.3	4.6	5.5	1.9	2.3
Current tobacco smoking	2.2	3.6	6.5	0.8	-2.6
Maternal smoking around birth	2.2	3.2	4.9	-2.2	-1.2
Asthma	2.2	4.4	5.2	1.9	2.3
Handedness (chirality/laterality): Left-handed	2.2	2.6	4.7	2.2	0.7
Heart disease (siblings)	2.2	2.6	5.2	-0.3	-2.3
Shortness of breath walking on level ground	2.0	2.4	3.4	-1.8	1.2
Mood swings	2.0	3.6	3.7	-1.9	-1.8
Medication: Lisinopril	2.0	2.6	4.2	-2.0	-1.0
Basal cell carcinoma (self-reported)	2.0	2.3	4.6	-2.1	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	2.5	-1.6	-1.2
Depressed Affect (Nagel 2018)	1.8	3.8	6.3	-1.1	-2.5
Forced vital capacity (FVC), Best measure	1.8	6.7	10.1	-3.2	1.8
Wears glasses or contact lenses	1.8	2.0	4.0	0.2	-2.0
Neuroticism (2016)	1.7	2.5	4.6	-0.6	-2.1
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	3.8	-0.4	1.9
Osteoporosis (self-reported)	1.7	2.1	3.8	-0.6	-2.0
Average weekly champagne plus white wine intake	1.7	2.4	3.9	2.0	0.9
Alcohol drinker status: Never	1.7	2.0	2.6	1.6	1.2
Smoking Status	1.6	3.9	7.8	-0.1	-2.8
Hayfever, allergic rhinitis or eczema	1.6	3.4	6.0	0.9	2.4
Financial difficulties in last 2 years	1.6	2.2	4.0	-0.6	-2.0
Worrier / anxious feelings	1.6	3.1	3.3	1.8	-1.7
Happiness	1.6	1.9	2.7	-1.6	-1.1
Commuting to job workplace: Cycle	1.6	1.9	3.8	-0.1	2.0
Forced vital capacity (FVC)	1.5	5.6	10.1	-3.2	1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	7.1	-0.1	-2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	2.5	1.5	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	3.7	1.9	0.4
Overall health rating	1.5	3.2	5.7	-0.8	-2.4
Body mass index (BMI)	1.4	5.9	9.9	-3.1	-1.4
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	3.1	-1.8	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	1.7	-1.3	1.2
Arm fat-free mass (right)	1.4	7.3	14.5	-3.8	-0.4
Health satisfaction	1.4	1.8	3.1	-1.8	-0.7
Medication: Seretide 50 evohaler	1.4	1.6	3.0	-1.7	0.4
Leg pain on walking	1.4	1.8	3.4	-1.8	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.7	3.0	0.6	-1.7
Arm fat-free mass (left)	1.4	7.2	14.2	-3.8	-0.3
Reaction Time	1.3	2.6	2.7	1.5	1.7
Rheumatoid Arthritis	1.3	1.9	3.0	-0.9	-1.7
Leg fat-free mass (left)	1.3	6.9	13.7	-3.7	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	5.3	-0.7	-2.3
Impedance of leg (left)	1.3	6.5	12.0	3.5	1.0
Leg predicted mass (left)	1.3	6.8	13.5	-3.7	-0.3
Allergy	1.3	2.9	5.7	-0.4	-2.4
Number of live births	1.3	1.9	3.7	-1.9	-0.3
Leg fat mass (right)	1.3	5.2	8.9	-3.0	-1.2
Whole body fat-free mass	1.3	7.2	14.3	-3.8	-0.2
Whole body water mass	1.3	7.3	14.5	-3.8	-0.2
Basal metabolic rate	1.3	7.1	14.1	-3.8	-0.3
Pain experienced in last month	1.3	2.1	3.8	-0.7	2.0
Arm predicted mass (left)	1.3	6.7	13.4	-3.7	-0.1
Depression (Nagel 2018)	1.2	1.7	3.2	-0.6	-1.8
Allergy or Eczema	1.2	3.1	5.3	0.9	2.3
Hypothyroidism (self reported)	1.2	2.9	3.1	-1.8	-1.6
Weight	1.2	6.1	11.4	-3.4	-0.9
Impedance of arm (right)	1.2	5.6	10.8	3.3	0.6
Trunk fat-free mass	1.2	6.9	13.8	-3.7	-0.1
Trunk predicted mass	1.2	7.1	14.1	-3.8	-0.1
Peak expiratory flow (PEF)	1.2	2.7	5.5	-2.3	-0.1
Medication: Allopurinol	1.2	1.6	2.0	-1.4	-1.1
Arm predicted mass (right)	1.2	6.3	12.3	-3.5	-0.6
Pulse rate, automated reading	1.2	4.0	7.7	-2.8	-0.5
Family relationship satisfaction	1.2	1.5	1.7	-1.2	-1.3
Qualifications: nursing, teaching	1.2	1.9	2.1	1.3	1.5
Smoking status: Current	1.2	1.9	3.2	0.8	-1.8
Impedance of whole body	1.2	6.1	11.4	3.4	0.9
Leg fat mass (left)	1.2	4.6	8.3	-2.9	-1.0
Neuroticism (Nagel 2018)	1.1	2.6	5.1	-0.1	-2.3
Coronary Artery Disease (CAD)	1.1	1.4	1.5	1.1	1.2
BMI	1.1	6.6	12.2	-3.5	-1.0
Vitamin and mineral supplements	1.1	1.5	2.2	-1.5	0.9
Waist circumference	1.1	4.1	7.9	-2.8	-0.6
Qualifications: None of the above	1.1	2.4	4.6	-0.3	-2.1
Falls in the last year	1.1	1.4	2.6	-0.5	-1.6
Impedance of arm (left)	1.1	5.2	9.8	3.1	0.8
Headache pain in last month	1.1	1.9	2.6	1.6	-1.1
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	3.8	-1.9	-0.6
Comparative body size at age 10	1.1	3.1	5.3	-2.3	-1.0
Leg fat-free mass (right)	1.1	5.8	11.6	-3.4	-0.2
Leg predicted mass (right)	1.1	5.8	11.5	-3.4	-0.1
Pain type(s) experienced in last month: Hip pain	1.1	1.4	2.4	-0.6	-1.6
Irritability	1.1	1.8	2.6	-1.0	-1.6
Alzheimer’s Disease (including proxy)	1.0	1.4	2.1	1.5	0.8
Prostate Cancer	1.0	1.4	1.7	1.3	1.0
Lupus	1.0	1.6	3.1	-1.8	-0.2
Schizophrenia (2014)	1.0	2.1	3.7	-1.9	-0.7
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.4	-1.5	0.2
Leg fat percentage (right)	1.0	3.4	5.6	-2.4	-1.1
Back pain experienced in last month	1.0	1.5	1.8	1.4	-1.1
Bipolar Disorder (2018)	0.9	1.4	2.7	0.4	-1.6
Irritable Bowel Disease (IBD)	0.9	2.1	3.0	1.1	1.7
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.7	1.3	0.6
Systolic Blood Pressure	0.9	4.4	7.7	2.8	1.0
Type 2 Diabetes (T2D) (2018)	0.9	1.7	2.0	1.4	-1.2
Impedance of leg (right)	0.9	4.3	8.0	2.8	0.7
Trunk fat mass	0.9	3.9	6.6	-2.6	-1.1
Hair/balding pattern: Pattern 2	0.9	1.1	1.9	-1.4	0.5
Mouth/teeth dental problems	0.9	1.3	1.6	1.3	1.0
Alcohol intake versus 10 years previously	0.9	1.4	1.4	-1.2	1.2
Noisy workplace	0.9	1.2	1.8	-0.7	-1.4
Arm fat mass (right)	0.9	3.9	6.8	-2.6	-1.0
Gout (self-reported)	0.9	1.2	2.5	-1.6	0.2
Whole body fat mass	0.9	3.9	6.8	-2.6	-1.0
Medication: Aspirin	0.9	1.2	2.4	-1.5	0.0
Arm fat mass (left)	0.9	3.9	7.0	-2.6	-0.8
Body Mass Index (BMI) (2010)	0.8	1.2	1.8	-1.4	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.4	-0.9	-1.2
Age when periods started (menarche)	0.8	2.0	3.8	-0.4	-1.9
Diabetes (self-reported)	0.8	1.3	2.5	0.2	-1.6
Arm fat percentage (right)	0.8	3.2	4.3	-2.1	-1.5
Mouth/teeth dental problems: Dentures	0.8	1.3	2.3	-1.5	-0.6
Birth weight of first child	0.8	1.4	2.8	-0.0	-1.7
Medication: Paracetamol	0.8	1.3	1.8	0.8	-1.4
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.7	-0.4	1.3
Worry too long after embarrassment	0.8	1.3	2.6	-0.3	-1.6
Number of children fathered	0.8	0.9	1.8	-0.1	1.3
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.7	-1.3	-0.2
Heart disease (mother)	0.8	1.0	1.9	-0.1	-1.4
Smoking status: Previous	0.8	1.3	2.5	-0.2	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.3	0.1	1.8
Arm fat percentage (left)	0.8	3.3	4.9	-2.2	-1.3
Diabetes diagnosed by doctor	0.8	1.3	2.1	0.7	-1.5
Miserableness	0.8	1.5	2.1	-0.9	-1.4
Leg fat percentage (left)	0.8	2.9	5.0	-2.2	-1.0
Schizophrenia vs Biploar Disorder	0.7	1.0	1.6	-1.2	0.6
Crohns Disease (2017)	0.7	1.6	2.4	0.9	1.5
HDL Cholesterol	0.7	1.2	1.6	1.3	0.9
Triglycerides	0.7	1.1	2.3	-1.5	-0.0
Neuroticism	0.7	1.7	3.2	-0.4	-1.8
Sensitivity / hurt feelings	0.7	1.2	2.3	0.3	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.1	-1.4	-0.5
Medication: Lansoprazole	0.7	0.8	1.5	0.3	-1.2
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.5	-0.3	-1.2
Body fat percentage	0.7	2.7	3.7	-1.9	-1.3
Medication for pain relief, constipation, heartburn	0.7	1.1	2.2	-0.1	1.5
Knee pain experienced in last month	0.7	1.1	2.2	-0.2	-1.5
Illnesses of siblings: Diabetes	0.7	0.9	1.8	0.0	-1.3
Friendships satisfaction	0.7	0.8	1.6	-1.3	-0.2
Hearing aid user	0.7	0.8	0.9	0.9	0.9
Commuting to job workplace: Public transport	0.7	0.9	1.3	0.6	-1.1
Medication: Blood pressure	0.7	1.4	2.6	-1.6	0.3
Fractured/broken bones in last 5 years	0.7	0.9	1.8	1.3	-0.3
Unable to work because of sickness or disability	0.7	0.9	1.5	0.6	-1.2
Cholesterol lowering medication	0.7	1.0	1.9	-0.3	1.4
Age at First Birth	0.6	0.9	1.2	1.1	-0.7
Primary Biliary Cirrhosis	0.6	0.9	1.8	1.3	-0.1
Ulcerative Colitis	0.6	0.9	1.7	1.3	0.1
Heel T-Score	0.6	4.4	7.4	-2.7	-1.2
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.4	-1.2	-0.6
Diabetes (father)	0.6	0.7	1.0	-0.6	1.0
Alcohol usually taken with meals	0.6	1.0	1.3	1.1	0.8
Heart attack	0.6	0.7	1.4	0.1	1.2
Illnesses of siblings	0.6	0.9	1.1	0.8	1.1
Neuroticism score	0.6	1.3	2.6	0.4	-1.6
Hip circumference	0.6	2.8	5.4	-2.3	-0.3
Time employed in main current job	0.6	0.7	1.4	0.2	1.2
Prospective memory result	0.6	0.7	1.5	-1.2	-0.2
Pulse wave Arterial Stiffness index	0.6	0.7	1.3	-0.4	-1.1
Breastfed as a baby	0.6	0.7	1.2	0.4	-1.1
Loud music exposure frequency	0.6	0.7	1.3	0.4	-1.1
Pulse wave peak to peak time	0.6	0.7	1.3	0.4	1.1
Mineral and other dietary supplements	0.6	0.7	1.3	0.4	1.2
Osteoarthritis (self-reported)	0.6	0.7	1.3	-0.5	-1.1
Medication: Atorvastatin	0.6	0.7	1.1	1.1	0.5
Age started oral contraceptive pill	0.6	0.7	1.3	-1.1	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	0.9	0.8	-0.9
Worry (Nagel 2018)	0.5	1.0	1.1	1.0	-1.0
Ulcerative Colitis (UC)	0.5	1.0	1.1	1.0	1.1
HbA1C	0.5	0.5	1.0	-1.0	0.2
Trunk fat percentage	0.5	2.1	3.0	-1.7	-1.1
Medication: Atenolol	0.5	0.7	1.3	0.0	1.1
Fluid intelligence score	0.5	1.0	1.7	-1.3	0.5
Exposure to tobacco smoke at home	0.5	0.6	1.0	1.0	-0.5
Pulse wave reflection index	0.5	0.7	0.8	0.7	0.9
Exposure to tobacco smoke outside home	0.5	0.7	1.3	-1.1	-0.3
Age at first live birth	0.5	0.9	1.9	1.4	0.0
Mean time to correctly identify matches	0.5	0.9	1.5	0.6	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	0.7	-0.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.2	-1.1	-0.1
Long-standing illness, disability or infirmity	0.5	0.7	0.9	-1.0	0.7
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.8	0.6	-0.9
Alcohol drinker status: Previous	0.5	0.6	1.2	-1.1	-0.0
Bipolar Disorder or Schizophrenia	0.4	1.1	1.7	-0.7	-1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	0.7	0.8	0.5
Medication: Metformin	0.4	0.6	1.2	0.3	1.1
Relative age voice broke	0.4	0.5	1.1	-1.0	0.0
Past tobacco smoking	0.4	0.7	1.4	0.2	1.2
Pulse rate	0.4	0.8	1.4	-1.2	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.8	1.6	1.3	0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.8	0.9	0.3
Birth weight	0.4	0.9	1.7	-1.3	-0.4
Emphysema/chronic bronchitis	0.4	0.4	0.7	-0.3	-0.8
Neck or shoulder pain in last month	0.4	0.5	0.7	-0.6	-0.8
Alcohol intake frequency.	0.4	0.9	1.4	-0.7	1.2
Number of full sisters	0.4	0.5	0.9	-0.9	0.4
Loneliness, isolation	0.4	0.6	0.9	0.5	-1.0
Illnesses of father: None of the above (group 1)	0.4	0.4	0.5	0.6	-0.7
Medication: Bendroflumethiazide	0.4	0.5	0.7	0.6	0.9
Illnesses of father: High blood pressure	0.4	0.5	0.9	-1.0	0.2
Myopia	0.4	0.7	1.3	-1.1	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.0	1.4	1.2	-0.8
Schizophrenia (2018)	0.3	0.7	1.3	-1.1	-0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.5	0.2	1.2
Mean Putamen Volume	0.3	0.3	0.4	0.7	0.4
Relative age of first facial hair	0.3	0.6	1.1	-1.0	-0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.6	0.4	0.8
Medication for hormone replacement therapy	0.3	0.3	0.7	-0.8	-0.2
Severe depression (siblings)	0.3	0.4	0.7	-0.9	0.1
Average weekly fortified wine intake	0.3	0.4	0.6	0.4	-0.8
Multivitamins +/- minerals	0.3	0.4	0.5	0.6	-0.7
Supplements: Glucosamine	0.3	0.4	0.7	-0.3	-0.9
Number of incorrect matches in round	0.3	0.5	0.6	0.6	-0.8
Nervous feelings	0.3	0.6	0.8	0.7	-0.9
Had other major operations	0.3	0.4	0.8	-0.9	-0.1
Medication: Cholesterol lowering	0.3	0.5	0.6	0.8	-0.6
Illnesses of mother	0.3	0.4	0.4	-0.6	-0.7
Hair/balding pattern: Pattern 4	0.3	0.7	1.2	-1.1	0.6
Wheeze or whistling in the chest in last year	0.3	0.5	0.7	0.5	0.8
Comparative height size at age 10	0.3	1.6	3.1	-0.2	1.8
Suffer from ‘nerves’	0.3	0.5	0.9	0.9	0.4
Had major operations	0.3	0.4	0.7	-0.8	0.2
Hypertension (Self-reported)	0.3	0.9	1.2	-1.1	0.8
Average weekly red wine intake	0.3	0.4	0.7	-0.8	-0.3
Breast cancer (self-reported)	0.3	0.4	0.6	0.8	0.3
Medication: Aspirin	0.3	0.5	0.9	-0.9	0.2
Number of self-reported non-cancer illnesses	0.3	0.5	0.7	-0.8	0.5
Mother’s age at death	0.3	0.4	0.6	0.5	-0.8
Ever smoked	0.3	0.6	1.1	0.2	-1.0
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.8	-0.0	0.9
Major Depression (MDD)	0.2	0.2	0.2	-0.5	0.5
Ovarian Cancer	0.2	0.2	0.3	-0.3	0.5
Crohns Disease (2012)	0.2	0.4	0.6	0.8	0.4
LDL Cholesterol	0.2	0.4	0.6	-0.4	0.8
Blood Eosinophil Count	0.2	1.3	2.4	-1.5	0.5
Blood Platelet Count	0.2	2.3	3.1	1.8	-1.3
Chronotype (morning person)	0.2	0.5	0.8	0.5	-0.9
Hand grip strength (left)	0.2	0.5	0.9	-1.0	0.2
Hearing difficulty/problems: Yes	0.2	0.3	0.4	0.4	0.6
Medication: Co-codamol	0.2	0.2	0.3	0.6	-0.4
Diabetes (mother)	0.2	0.3	0.5	0.7	-0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.3	0.5	-0.2
Qualifications: CSEs or equivalent	0.2	0.2	0.3	-0.5	-0.4
High blood pressure	0.2	0.5	0.8	-0.9	0.4
Stomach or abdominal pain in last month	0.2	0.2	0.4	0.7	0.1
Sitting height	0.2	1.5	2.9	-1.7	0.5
Chronic bronchitis/emphysema (father)	0.2	0.3	0.4	0.7	0.3
Hearing difficulty/problems with background noise	0.2	0.3	0.6	-0.8	0.2
Had menopause	0.2	0.2	0.3	-0.3	0.6
Father’s age at death	0.2	0.3	0.4	-0.3	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.6	0.1	-0.8
Depression (self-reported)	0.2	0.3	0.5	0.1	-0.7
Lung cancer (father)	0.2	0.2	0.3	0.6	-0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.3	-0.6	0.3
Glaucoma (self-reported)	0.2	0.2	0.3	-0.6	0.4
Medication: Amlodipine	0.2	0.3	0.5	-0.7	0.2
Number of full brothers	0.2	0.3	0.3	0.5	-0.6
Qualifications: College or University degree	0.2	0.6	1.1	0.1	1.1
Eye problems/disorders: None of the above	0.2	0.2	0.4	-0.1	-0.7
Medication: Ibuprofen	0.2	0.3	0.5	0.3	-0.7
Illnesses of father: Heart disease	0.2	0.3	0.3	-0.5	-0.5
Eye problems/disorders: Cataract	0.2	0.3	0.3	-0.5	0.5
Medication: Gliclazide	0.2	0.3	0.4	0.4	0.6
Guilty feelings	0.2	0.3	0.4	-0.6	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.4	-0.6	-0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	0.7	0.2
High cholesterol (Self-reported)	0.2	0.3	0.5	0.7	-0.4
Ever depressed for a whole week	0.2	0.3	0.5	0.7	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.3	-0.6	0.4
Breast Cancer	0.1	0.2	0.4	-0.7	0.1
Blood Red Count	0.1	0.9	1.5	-0.5	-1.2
Blood White Count	0.1	0.5	0.7	-0.8	-0.6
Height	0.1	1.3	2.2	-1.5	-0.5
Tanning	0.1	0.9	1.6	0.4	1.2
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.3	0.3
Systolic blood pressure, automated reading	0.1	0.3	0.6	0.1	-0.7
Supplements: Zinc	0.1	0.1	0.2	-0.3	0.4
Hand grip strength (right)	0.1	0.3	0.5	-0.7	0.2
High blood pressure (mother)	0.1	0.1	0.3	-0.2	-0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	-0.3	0.3
Medication: Ramipril	0.1	0.2	0.3	0.0	0.6
Hair/balding pattern: Pattern 3	0.1	0.1	0.1	0.2	-0.3
Standing height	0.1	1.0	1.3	-0.8	1.1
Length of working week for main job	0.1	0.1	0.2	0.3	-0.5
Tense / ‘highly strung’	0.1	0.2	0.3	-0.2	-0.6
High blood pressure (siblings)	0.1	0.2	0.3	-0.3	-0.5
Medication: Blood pressure	0.1	0.3	0.3	-0.5	0.5
Medication: Omeprazole	0.1	0.1	0.2	0.5	-0.2
Age at last live birth	0.1	0.2	0.3	0.6	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.4	-0.3
Ever had bowel cancer screening	0.1	0.1	0.3	-0.5	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.4	-0.1	-0.6
Medication for cholesterol	0.1	0.2	0.3	0.5	-0.3
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.4	0.2
Medication: Paracetamol	0.1	0.1	0.2	0.2	-0.4
Diastolic blood pressure, automated reading	0.1	0.5	0.9	-0.2	-0.9
Alzheimer’s Disease (in mother)	0.0	0.0	0.0	0.2	-0.1
Waist Hip Ratio (WHR)	0.0	0.2	0.4	-0.7	0.0
Cardiovascular Disease	0.0	0.0	0.0	0.2	-0.0
Hair Pigment	0.0	0.1	0.2	0.5	0.1
Number of treatments/medications taken	0.0	0.0	0.0	0.1	-0.2
Angina	0.0	0.0	0.0	-0.2	0.1
Taking other prescription medications	0.0	0.0	0.0	0.1	0.1
Serious illness, injury or assault to yourself	0.0	0.0	0.0	0.1	-0.1
Medication: Simvastatin	0.0	0.1	0.1	0.1	0.3
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.0	0.1
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.0	-0.1	-0.1
Angina (self-reported)	0.0	0.1	0.1	-0.2	0.2
Chest pain or discomfort	0.0	0.0	0.0	-0.0	-0.1
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.1	0.1	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	-0.0	-0.3
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	0.2	-0.2
Supplements: Calcium	0.0	0.1	0.1	0.3	0.1

Hub : Genes

KIAA0802

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