Hub : Genes

CLIC6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1030	0.0400	6.7e-03	0.141	NA	0.107	NA	0.126	1.3e-11	NA	4.8e-09	NA	1.8e-10
2	GTEx	Colon Transverse	0.2050	0.0660	3.0e-03	0.063	NA	0.032	NA	0.034	6.0e-04	NA	1.1e-02	NA	9.7e-03
3	GTEx	Esophagus Gastroesophageal Junction	0.2450	0.0780	3.6e-03	0.247	NA	0.240	NA	0.240	1.9e-09	NA	3.6e-09	NA	3.4e-09
4	GTEx	Esophagus Muscularis	0.1740	0.0590	4.0e-03	0.131	NA	0.121	NA	0.111	2.4e-08	NA	8.3e-08	NA	3.1e-07
5	GTEx	Lung	0.1974	0.0449	3.1e-06	0.107	NA	0.112	NA	0.124	1.5e-08	NA	7.1e-09	NA	1.0e-09
6	GTEx	Pituitary	0.5590	0.1010	2.1e-05	0.307	NA	0.315	NA	0.328	1.9e-08	NA	1.1e-08	NA	4.9e-09
7	GTEx	Skin Sun Exposed Lower leg	0.1180	0.0440	4.0e-03	0.000	NA	0.016	NA	0.001	3.4e-01	NA	1.7e-02	NA	2.6e-01
8	METSIM	Adipose	0.1795	0.0328	2.1e-12	0.168	0.097	0.150	0.153	0.168	2.0e-24	2.6e-14	9.1e-22	3.5e-22	1.9e-24
9	YFS	Blood	0.0587	0.0162	4.8e-06	0.030	0.016	0.026	0.041	0.030	3.0e-10	3.2e-06	4.5e-09	2.8e-13	3.2e-10
10	TCGA	Breast Invasive Carcinoma	0.0118	0.0062	4.6e-03	0.014	0.010	0.009	NA	0.011	4.7e-04	3.2e-03	3.8e-03	NA	2.2e-03
11	TCGA	Glioblastoma Multiforme	0.1980	0.0950	3.0e-03	-0.004	0.073	0.056	NA	0.006	4.5e-01	3.1e-03	8.5e-03	NA	2.1e-01
12	TCGA	Brain Lower Grade Glioma	0.0388	0.0184	1.4e-04	0.059	0.040	0.043	NA	0.052	2.8e-07	2.0e-05	9.9e-06	NA	1.5e-06
13	TCGA	Lung Adenocarcinoma	0.0298	0.0169	2.9e-03	0.042	0.012	0.025	NA	0.033	1.0e-05	1.2e-02	6.2e-04	NA	7.7e-05
14	TCGA	Stomach Adenocarcinoma	0.0610	0.0340	3.6e-03	0.006	0.025	0.019	NA	0.018	1.2e-01	5.7e-03	1.4e-02	NA	1.6e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.1	0.2	0.6	-0.7	-0.3	-0.2	-0.3	-0.3	-0.2	-0.8	-0.5	-0.0	0.1	0.1	-0.3	0.3	0.7
Bipolar Disorder or Schizophrenia	0.2	0.5	1.9	-0.6	-0.7	-0.1	0.4	0.0	0.6	0.4	-0.6	-0.2	-0.9	1.1	0.5	-0.5	-1.4
Depressed Affect (Nagel 2018)	0.3	0.7	3.4	-1.1	-0.7	-0.7	-0.2	-0.8	0.3	-1.1	-0.9	1.8	-0.6	0.9	-0.1	0.1	-0.4
Depression (Nagel 2018)	1.3	1.9	6.4	0.8	-1.1	-2.4	-2.5	-2.2	0.2	-0.7	0.9	2.4	0.1	-0.3	0.2	-0.2	0.7
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.6	1.3	0.7	1.2	0.4	1.0	-0.9	1.6	1.3	-0.8	0.6	0.1	-0.9	0.9	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	1.0	-0.9	0.2	-0.3	-0.2	0.1	-0.3	-0.6	-0.5	-0.0	0.4	-0.3	-0.3	0.3	1.0
Schizophrenia (2018)	0.5	1.0	5.4	-0.3	-0.6	0.0	0.8	0.3	1.0	1.2	-0.5	-0.3	-1.3	1.4	0.9	-0.9	-2.3
Schizophrenia vs Biploar Disorder	0.4	0.5	1.7	-0.0	-0.7	-0.6	-0.2	-0.4	0.8	-0.2	-0.1	1.3	-0.7	0.3	0.8	-0.8	-1.3
Worry (Nagel 2018)	0.5	1.1	4.9	0.7	0.6	-0.3	-0.5	0.3	-1.0	0.6	1.1	-1.5	1.0	-1.5	-0.9	0.9	2.2
Alzheimer’s Disease (in mother)	1.7	2.0	6.6	1.0	1.2	0.0	-0.0	0.5	-1.5	2.3	1.2	0.0	1.7	-2.0	-1.1	1.1	2.6
Alzheimer’s Disease (in father)	1.4	1.5	3.8	-1.9	-0.2	0.4	0.5	-0.1	1.0	-0.7	-1.8	1.9	-0.3	1.3	1.8	-1.8	-0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	2.3	-0.4	-0.2	-0.3	-0.3	-0.7	0.4	0.5	-0.3	1.5	0.2	0.3	1.2	-1.2	0.6
Crohns Disease (2017)	0.6	1.3	3.8	-0.1	-1.7	-1.6	-1.3	-1.9	1.0	-0.0	0.0	-0.5	-1.2	2.0	0.8	-0.8	-0.5
Irritable Bowel Disease (IBD)	0.3	0.8	2.0	1.3	-0.8	-1.4	-1.3	-1.3	-0.1	0.7	1.4	-0.4	-0.3	0.8	-0.3	0.3	0.5
Ulcerative Colitis (UC)	0.7	1.3	4.1	2.0	0.5	-0.5	-0.7	-0.1	-1.2	1.3	2.0	-0.8	0.9	-0.7	-1.2	1.2	1.3
Major Depression (MDD)	0.7	0.8	2.2	-0.8	0.6	1.5	1.0	1.4	-0.4	1.2	-0.9	-0.7	0.3	0.8	-0.5	0.5	-0.9
Reaction Time	0.7	1.2	2.3	0.9	0.9	-0.4	-0.5	0.1	-1.4	1.5	0.7	-1.3	1.2	-1.4	-1.4	1.4	1.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	2.8	-0.3	-0.2	0.8	0.5	0.6	0.2	0.4	-0.1	0.2	-0.4	1.3	0.1	-0.1	-1.7
Breast Cancer	1.4	3.4	9.8	-2.2	0.4	3.1	2.8	2.2	1.5	-1.5	-2.1	-0.2	-0.7	0.3	1.9	-1.9	-1.7
Ovarian Cancer	8.1	10.7	27.1	4.6	3.2	0.1	0.0	1.7	-3.4	3.1	4.5	-1.9	3.7	-5.2	-3.2	3.2	3.3
Prostate Cancer	2.4	3.3	7.4	-2.7	-1.4	1.2	0.8	-0.1	2.0	-1.5	-2.6	-1.1	-1.9	2.5	2.0	-2.0	-1.6
Age at First Birth	0.9	1.3	3.5	-1.9	-1.3	-0.7	-0.7	-1.0	1.0	-1.1	-1.7	0.7	-1.2	1.4	0.8	-0.8	0.3
Bipolar Disorder (2011)	1.5	1.5	3.8	-1.9	-1.2	-0.7	-0.1	-1.1	1.2	-1.5	-1.7	-0.1	-1.3	1.9	0.9	-0.9	-0.3
Body Mass Index (BMI) (2010)	0.2	0.3	1.9	0.6	-0.1	0.8	0.6	0.1	0.2	0.3	0.5	0.5	-0.5	-0.1	0.1	-0.1	-1.4
Coronary Artery Disease (CAD)	0.6	0.7	3.1	0.2	-0.9	-1.8	-1.4	-1.1	0.6	0.1	0.1	0.5	-0.6	-0.6	0.6	-0.6	0.4
Crohns Disease (2012)	0.3	0.5	1.8	1.3	-0.3	-0.5	-0.6	-0.7	0.0	0.9	1.3	-1.1	-0.1	-0.4	0.2	-0.2	-0.0
Mean Putamen Volume	0.3	0.4	1.7	-0.3	0.4	0.7	0.3	1.0	0.3	-0.2	-0.2	-1.3	0.3	-0.8	0.7	-0.7	0.1
Fasting Glucose	2.3	2.8	8.2	-1.8	-0.3	2.0	2.0	1.2	1.5	-1.0	-1.9	-1.8	-1.4	1.3	1.4	-1.4	-2.9
HbA1C	0.9	1.0	2.6	-0.3	-1.6	-1.6	-1.4	-1.5	1.0	-0.1	-0.3	0.5	-1.0	0.4	1.1	-1.1	0.1
HDL Cholesterol	0.2	0.3	1.2	0.5	0.5	0.0	-0.4	0.3	-0.6	1.1	0.6	-0.5	0.8	-0.2	-0.4	0.4	0.2
LDL Cholesterol	1.2	1.9	3.3	1.2	1.6	1.8	1.4	1.6	-1.3	1.6	1.4	1.1	1.2	-1.2	-1.3	1.3	1.3
Lupus	0.6	0.8	4.4	0.7	0.7	0.4	0.3	0.7	-0.6	1.1	0.4	-2.1	0.6	-1.4	-0.7	0.7	1.0
Neuroticism (2016)	0.4	0.5	2.8	0.1	0.4	-0.3	-0.8	0.3	-0.8	1.7	0.3	-0.2	1.0	-0.4	-0.7	0.7	1.0
Primary Biliary Cirrhosis	0.6	0.9	3.2	0.2	-1.2	-1.6	-1.8	-1.3	0.4	-0.4	0.1	-1.6	-0.7	0.4	0.0	-0.0	0.1
Rheumatoid Arthritis	0.3	0.5	0.9	0.8	-0.3	-0.4	-0.2	-0.4	0.8	-0.8	0.9	-0.9	-0.3	-0.6	1.0	-1.0	-0.4
Schizophrenia (2014)	0.3	0.6	3.7	-0.4	-0.2	0.2	0.7	0.6	0.4	1.3	-0.6	0.2	-0.7	0.9	0.3	-0.3	-1.9
Triglycerides	0.3	0.4	2.3	-0.5	0.3	1.1	1.0	0.6	0.0	-0.7	-0.4	1.5	-0.3	0.4	-0.1	0.1	0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.8	-0.8	-0.1	0.6	0.5	0.5	0.3	0.0	-0.9	-0.5	-0.1	-0.3	0.4	-0.4	-0.7
Ulcerative Colitis	0.6	0.9	2.2	1.3	0.7	0.8	0.7	1.0	-0.6	1.5	1.3	-1.4	0.4	-0.4	-0.9	0.9	0.3
Blood Eosinophil Count	0.2	1.3	7.9	-0.6	1.3	0.4	1.8	0.9	-0.9	2.8	-0.5	0.8	1.4	0.1	-0.4	0.4	0.7
Blood Platelet Count	0.3	2.9	9.2	-1.9	1.0	3.0	2.7	2.1	0.4	1.5	-1.9	-2.6	-0.3	0.2	0.6	-0.6	-1.2
Blood Red Count	0.1	1.1	2.9	-1.6	0.8	0.6	1.4	0.7	-0.9	1.7	-1.6	-0.6	0.9	0.0	-0.9	0.9	1.0
Blood White Count	0.4	2.7	6.2	-2.2	0.8	2.5	2.4	2.0	0.6	2.0	-2.3	-0.5	-0.1	0.5	1.1	-1.1	-2.0
Heel T-Score	0.2	1.7	4.6	2.1	-0.7	-1.0	-0.6	-1.1	1.0	1.3	2.0	1.8	-0.6	-1.5	1.3	-1.4	-0.3
BMI	0.7	4.1	9.0	-0.2	3.0	2.8	2.7	3.0	-2.1	0.9	-0.4	-1.7	2.1	-1.3	-2.1	2.1	0.5
Height	0.1	1.3	4.0	0.6	-1.7	-1.0	-1.6	-1.4	0.7	-2.0	1.0	0.5	-1.0	0.3	0.4	-0.4	1.3
Waist Hip Ratio (WHR)	0.3	1.6	6.4	-0.7	-1.3	-0.9	-1.1	-1.3	1.2	-2.5	-0.5	0.4	-1.0	1.9	1.1	-1.1	-0.7
Systolic Blood Pressure	0.1	0.5	1.6	-1.1	-0.3	0.6	0.3	-0.2	0.6	0.5	-1.3	-1.2	-0.4	0.5	0.8	-0.8	-0.1
Smoking Status	0.5	1.2	4.5	-0.7	-0.9	0.3	0.5	-0.1	1.4	-1.2	-0.7	1.1	-1.3	1.2	1.3	-1.3	-2.1
Allergy or Eczema	0.3	0.8	2.0	-0.4	1.0	-0.2	0.4	0.4	-1.4	0.4	-0.4	0.0	1.2	0.3	-1.4	1.4	1.1
Cardiovascular Disease	0.9	2.9	7.9	-2.8	0.2	2.2	2.0	1.2	0.7	-2.5	-2.8	-0.7	-0.7	2.2	0.6	-0.6	-1.2
Hypothyroidism (self reported)	0.8	1.8	8.2	0.8	1.2	0.3	0.0	1.1	-1.2	1.4	0.5	-2.9	1.4	-2.4	-0.9	0.9	1.0
Respiratory disease	0.5	1.1	5.2	-1.6	-0.5	-0.7	0.0	-1.3	0.4	-2.3	-1.4	-0.2	-0.4	1.9	0.2	-0.2	0.0
Type 2 Diabetes (T2D) (2018)	0.6	1.1	3.5	-0.0	1.4	1.5	1.3	1.9	-0.7	1.2	-0.4	-1.2	0.8	-0.7	-0.3	0.3	-0.7
Lung FEV1/FVC ratio	1.5	7.7	29.4	-2.8	2.3	5.4	5.0	4.8	-0.8	-1.6	-2.9	-0.9	0.6	0.1	-1.0	1.0	-1.7
Lung FVC	5.8	29.4	54.2	6.3	4.4	-2.5	-2.5	0.5	-6.9	5.0	6.1	-1.1	6.2	-6.5	-6.9	6.9	7.4
Neuroticism	0.3	0.6	1.8	-0.5	-1.0	-0.8	-1.0	-1.1	0.3	-1.3	-0.1	1.3	-0.7	0.7	-0.0	0.0	0.4
Chronotype (morning person)	0.2	0.5	1.9	1.4	0.4	-0.8	-0.2	-0.6	-0.5	0.6	1.1	0.6	0.6	-1.3	-0.3	0.3	0.3
Hair Pigment	0.1	2.0	5.7	0.7	1.3	-1.1	-0.5	-0.0	-1.9	0.6	0.9	-0.2	1.9	-1.6	-1.9	1.9	2.4
Tanning	0.0	0.4	1.1	0.9	0.1	0.6	0.5	0.3	-0.3	0.1	0.9	0.9	0.2	-1.0	-0.5	0.5	-0.8
Hand grip strength (left)	0.6	1.5	3.2	1.6	1.2	1.1	0.8	1.2	-1.1	0.7	1.7	1.1	1.0	-1.8	-1.2	1.2	0.6
Number of treatments/medications taken	0.3	0.5	2.9	-0.0	0.9	0.3	0.4	0.6	-0.7	0.5	0.1	-1.7	0.9	0.5	-0.3	0.3	0.2
Average weekly spirits intake	0.2	0.2	0.5	-0.6	-0.5	0.2	-0.0	-0.1	0.6	-0.1	-0.6	-0.0	-0.6	-0.1	0.7	-0.7	-0.5
Sensitivity / hurt feelings	0.5	0.9	2.6	-0.9	-0.8	-0.6	-1.3	-0.5	0.9	-1.6	-0.6	0.1	-0.3	0.2	1.3	-1.4	0.8
Frequency of depressed mood in last 2 weeks	0.8	1.1	4.2	-0.3	-0.9	-1.7	-1.8	-1.6	0.3	-0.9	-0.2	2.0	-0.2	0.7	0.1	-0.1	0.3
Hearing difficulty/problems: Yes	0.7	1.1	4.4	-0.2	-1.0	-2.1	-2.1	-1.7	0.1	0.0	-0.1	-1.3	-0.2	1.1	-0.0	0.0	0.5
Relative age of first facial hair	0.6	1.2	5.0	2.1	-0.5	-1.4	-1.4	-1.2	-0.4	0.1	2.2	-0.1	0.2	-0.2	-0.7	0.7	0.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.2	4.1	-1.2	0.3	1.0	0.6	1.1	1.0	-0.0	-1.4	-0.2	-0.1	0.4	1.8	-1.8	-2.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.6	0.1	0.6	0.9	1.1	0.7	-0.3	0.3	0.2	-1.3	0.2	-0.1	-0.4	0.4	-0.1
Ever had hysterectomy (womb removed)	1.8	2.0	5.7	-1.4	-0.8	1.2	1.1	0.4	1.6	-1.4	-1.4	-1.5	-1.6	1.1	1.5	-1.5	-2.4
Systolic blood pressure, automated reading	0.3	0.8	4.8	-0.2	0.2	1.2	1.0	0.6	0.5	1.1	-0.3	-2.2	-0.2	-0.5	0.7	-0.7	-0.8
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	2.6	1.5	0.7	-0.5	-0.3	0.5	-0.8	1.6	1.3	-1.1	1.1	-1.6	-0.4	0.4	-0.0
Angina	0.8	1.1	3.5	0.2	1.5	0.9	1.1	1.3	-0.8	1.3	0.3	-1.9	1.4	-1.0	-0.1	0.1	-0.2
Medication for hormone replacement therapy	0.1	0.2	0.8	0.3	-0.2	0.3	0.2	-0.1	0.2	-0.1	0.4	-0.7	-0.4	-0.4	-0.2	0.2	-0.9
Vitamin and mineral supplements	0.8	1.1	2.4	-1.0	-0.0	1.1	1.1	0.9	1.0	-1.5	-1.2	-1.4	-0.9	-0.1	0.9	-0.9	-1.3
Supplements: Zinc	3.0	3.3	6.5	-0.6	-2.6	-1.3	-1.6	-2.1	2.1	-2.1	-0.5	1.6	-2.2	1.8	2.0	-2.0	-1.6
Medication: Co-codamol	1.5	1.7	3.8	0.9	2.0	1.2	1.3	1.3	-1.5	1.6	0.9	-1.4	1.6	-1.2	-0.9	0.8	1.3
Medication: Metformin	1.0	1.4	3.5	-1.0	1.5	1.8	1.9	1.9	-0.4	0.5	-1.4	-1.7	0.6	-0.4	-0.0	0.0	-1.2
Diabetes (father)	0.9	1.1	3.3	-1.3	-0.7	0.7	0.0	0.1	0.9	-0.6	-1.3	1.8	-1.1	1.8	0.5	-0.5	-1.3
Diabetes (mother)	0.9	1.1	4.6	-1.4	-0.1	0.9	0.6	0.5	0.6	0.6	-1.4	-1.3	-0.7	2.1	0.6	-0.6	-1.6
Severe depression (siblings)	0.3	0.3	0.9	-0.7	-0.9	-0.0	-0.4	-0.5	0.6	0.4	-0.7	-0.4	-0.7	0.5	0.3	-0.3	-0.9
Pack years adult smoking proportion	0.2	0.3	1.4	-0.0	0.2	-0.6	-0.7	-0.2	-0.5	0.6	-0.2	0.4	0.6	-0.5	-0.5	0.5	1.2
Impedance of leg (right)	0.1	0.6	2.4	0.1	-0.5	-1.2	-1.6	-0.9	0.0	-1.2	0.3	-0.3	0.2	-0.9	0.2	-0.2	1.2
Leg fat-free mass (left)	0.2	0.9	2.9	-0.6	-0.4	1.5	1.0	0.7	0.9	-0.4	-0.7	0.3	-1.0	1.5	0.6	-0.6	-1.7
Trunk fat percentage	0.2	0.6	2.6	0.2	0.6	1.6	1.3	1.0	0.3	-0.5	0.2	-0.5	-0.1	0.0	0.6	-0.6	-1.4
Hand grip strength (right)	1.1	3.1	6.4	2.1	1.7	0.5	-0.0	1.3	-2.0	1.0	2.3	-0.1	2.0	-2.5	-2.0	2.0	2.3
Townsend deprivation index at recruitment	0.8	1.2	3.5	-1.5	0.1	0.1	0.7	0.3	0.8	-0.6	-1.7	0.5	-0.4	1.6	1.1	-1.1	-1.9
Current tobacco smoking	0.5	0.8	1.5	0.3	1.2	0.9	1.2	1.2	-0.7	1.2	0.3	1.2	0.8	-0.8	-0.6	0.6	-0.1
Average weekly fortified wine intake	1.3	1.5	4.4	2.0	-0.9	-1.8	-1.5	-1.4	0.3	1.2	2.1	0.2	-0.2	-1.3	0.5	-0.5	1.1
Maternal smoking around birth	0.3	0.4	1.7	-0.5	-0.5	-0.3	0.0	-0.3	0.5	-0.2	-0.5	1.3	-0.9	0.8	0.1	-0.1	-0.9
Fed-up feelings	0.3	0.5	6.1	-0.2	0.1	0.4	0.1	0.0	0.0	-0.2	-0.1	2.5	0.1	0.5	0.0	-0.0	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	6.9	1.3	-0.8	-2.3	-2.6	-2.0	-0.3	0.7	1.5	2.5	0.4	-0.2	-0.5	0.5	1.3
Relative age voice broke	0.6	0.9	4.0	1.9	-0.6	-1.1	-1.4	-0.6	0.0	-0.3	2.0	-0.8	-0.1	0.2	-0.1	0.1	-0.1
Taking other prescription medications	0.5	0.7	2.9	-0.3	1.1	0.7	0.8	1.2	-0.7	0.9	-0.4	-1.7	1.1	-0.5	-0.3	0.3	-0.2
Age when periods started (menarche)	0.4	1.0	1.9	-1.2	-1.4	-0.3	-0.7	-0.8	1.2	-0.7	-1.2	0.5	-1.4	1.1	0.9	-0.9	-1.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.4	-0.9	-1.2	-0.3	-0.3	-0.5	1.4	-1.7	-0.7	-0.9	-1.5	1.8	1.1	-1.1	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	4.4	2.0	0.0	-0.8	-0.7	-0.3	-0.0	2.1	1.8	0.8	0.2	-1.1	0.3	-0.3	-0.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.1	-0.8	0.3	0.7	0.5	0.6	-0.4	-0.6	-0.8	-1.0	0.2	0.3	-0.7	0.7	0.1
Qualifications: CSEs or equivalent	4.2	5.6	9.0	1.7	3.0	1.9	1.9	2.5	-2.8	3.0	1.7	-0.4	2.6	-2.5	-2.8	2.8	2.2
Serious illness, injury or assault to yourself	1.6	2.0	3.7	0.6	1.8	1.9	1.9	1.9	-1.3	1.8	0.6	0.5	1.3	-1.5	-1.1	1.1	1.2
High blood pressure	1.4	4.0	9.7	-3.0	0.2	2.8	2.8	1.6	0.9	-2.1	-3.1	-1.7	-1.0	2.0	0.8	-0.8	-2.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.1	-0.1	0.5	-0.2	0.0	0.3	-0.9	0.5	-0.2	-0.2	0.7	0.1	-1.0	1.0	0.5
Multivitamins +/- minerals	1.3	1.7	7.7	1.4	-0.1	-1.7	-1.6	-1.3	-0.7	1.1	1.6	2.8	0.7	0.3	-0.5	0.5	1.0
Stomach or abdominal pain in last month	0.8	1.0	2.1	0.7	0.6	-1.2	-0.9	-0.4	-1.1	-0.8	0.7	-1.5	1.2	-1.4	-0.9	0.9	1.4
Supplements: Glucosamine	1.5	2.0	6.1	1.2	1.5	0.6	0.5	1.0	-1.6	2.5	1.3	-1.2	1.8	-1.2	-1.4	1.4	1.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	3.4	1.4	1.6	0.9	1.0	1.1	-1.4	1.9	1.3	0.5	1.4	-1.8	-1.5	1.5	0.5
Medication: Atenolol	0.3	0.4	2.0	0.0	-0.2	0.1	0.3	-0.1	0.6	-0.1	-0.1	-0.1	-0.3	0.4	1.0	-1.0	-1.4
Medication: Levothyroxine sodium	0.9	1.5	4.9	0.9	1.2	0.1	0.1	1.1	-1.1	1.3	0.7	-2.2	1.5	-2.2	-0.8	0.8	0.7
Sitting height	0.5	3.3	5.7	-2.3	-2.0	1.3	0.2	0.1	2.3	-1.2	-2.2	0.7	-2.4	2.4	2.0	-2.0	-1.9
Chronic bronchitis/emphysema (father)	0.9	1.0	2.5	-0.7	-1.2	-0.3	-0.8	-0.8	1.1	-1.3	-0.9	0.7	-1.1	0.7	1.1	-1.1	-1.6
High blood pressure (mother)	0.5	0.6	1.1	-1.1	0.7	0.7	0.8	1.1	-0.8	-0.2	-1.0	-0.6	0.4	-0.8	-1.1	1.1	0.3
Body mass index (BMI)	0.8	3.5	11.6	0.3	2.5	3.4	3.2	3.0	-1.2	1.7	0.1	-1.0	1.2	-1.0	-1.1	1.1	-1.1
Impedance of leg (left)	0.1	0.7	2.7	0.2	-0.5	-1.4	-1.7	-1.1	-0.1	-1.1	0.3	-0.7	0.2	-0.7	0.1	-0.1	1.3
Leg predicted mass (left)	0.2	0.9	2.8	-0.7	-0.4	1.5	1.0	0.7	0.9	-0.4	-0.8	0.2	-1.0	1.5	0.6	-0.6	-1.7
Trunk fat mass	0.2	0.7	3.7	0.2	0.7	1.9	1.5	1.3	0.1	-0.1	0.2	-0.4	0.0	-0.0	0.3	-0.3	-1.4
Waist circumference	0.5	1.9	7.2	0.1	1.8	2.7	2.3	2.3	-0.9	0.7	-0.1	-1.1	0.9	-0.2	-0.9	0.9	-0.7
Number of incorrect matches in round	0.3	0.5	1.9	-1.4	-0.4	0.2	0.3	-0.0	0.6	0.4	-1.3	-0.7	-0.4	1.2	0.6	-0.6	-0.2
Past tobacco smoking	0.5	1.0	3.6	0.8	0.2	-0.5	-0.9	-0.5	-1.0	1.6	0.9	0.6	0.9	-0.8	-1.0	1.0	1.9
Alcohol usually taken with meals	1.0	1.6	6.0	-0.6	-2.3	-0.1	-0.1	-1.3	2.0	-0.6	-0.4	0.5	-2.4	1.0	1.4	-1.4	-0.6
Nervous feelings	2.5	4.7	8.7	1.3	2.5	0.8	0.8	1.9	-2.7	2.8	1.5	-1.1	2.7	-2.6	-2.5	2.5	3.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	6.4	0.6	-0.4	-1.4	-1.0	-1.2	0.4	0.1	0.7	2.5	0.1	-0.7	0.5	-0.5	0.7
Hearing difficulty/problems with background noise	0.6	1.0	3.7	-0.5	-1.3	-1.9	-1.8	-1.3	0.6	-0.2	-0.2	-0.7	-0.7	1.4	0.4	-0.4	0.2
Hair/balding pattern: Pattern 2	0.7	0.9	4.0	-1.7	-0.1	0.6	0.3	0.3	0.3	-1.5	-2.0	0.4	-0.5	1.4	0.0	0.0	-0.9
Had menopause	0.6	0.7	3.4	0.2	0.7	0.7	0.9	0.8	-0.7	1.2	0.2	-1.8	0.3	-0.4	-0.9	0.9	0.2
Had other major operations	0.6	0.7	3.8	1.5	0.5	0.2	0.2	0.3	-0.2	2.0	1.5	0.3	0.3	-0.5	-0.0	0.0	-0.5
Forced vital capacity (FVC)	2.6	10.0	21.2	3.8	1.4	-2.0	-2.6	-0.7	-3.8	1.6	3.7	-0.7	2.9	-3.0	-4.6	4.6	4.6
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	6.3	2.5	0.6	-0.2	0.0	0.1	-0.5	1.9	2.4	0.5	0.5	-1.9	-0.4	0.4	0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	-1.1	-0.4	-0.3	-0.6	-0.3	0.5	-0.1	-1.2	0.3	-0.3	0.7	0.5	-0.5	-0.6
Qualifications: None of the above	0.2	0.4	1.6	-1.1	0.0	-0.3	0.1	-0.0	0.2	-0.6	-1.3	-1.3	-0.1	0.2	-0.0	0.0	-0.6
Financial difficulties in last 2 years	0.2	0.3	1.6	0.7	0.3	-0.4	-0.5	0.0	-0.3	0.8	0.5	-0.7	0.4	-1.2	-0.0	0.0	0.4
Mouth/teeth dental problems	0.4	0.6	1.8	-0.6	1.0	1.0	1.0	1.1	-0.7	-0.7	-0.8	-1.4	0.6	0.0	-0.6	0.6	0.1
Heart attack	0.6	0.7	2.2	0.6	1.3	-0.2	0.1	0.4	-1.0	1.0	0.8	1.0	1.5	-1.1	-0.3	0.3	0.8
Allergy	0.3	0.7	1.4	0.1	-0.9	0.5	-0.0	-0.2	1.2	-1.0	0.2	0.8	-1.2	0.2	1.1	-1.1	-1.0
Pain all over the body in last month	1.1	1.2	4.0	0.3	1.4	0.8	0.9	1.4	-0.7	0.8	0.3	-2.0	1.4	-1.8	-0.1	0.1	0.6
Diabetes (self-reported)	0.7	1.1	4.2	-0.2	1.4	1.0	1.1	1.5	-0.8	1.3	-0.5	-2.1	0.9	-1.0	-0.5	0.5	-0.5
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.9	-1.7	0.3	0.9	0.9	0.7	-0.6	-0.8	-1.6	-0.7	0.1	0.8	-1.0	1.0	0.7
Medication: Ramipril	1.5	2.0	6.0	-1.7	0.9	2.5	2.4	1.7	0.3	-0.6	-1.8	-0.3	-0.1	1.1	0.7	-0.7	-1.8
Medication: Simvastatin	0.7	1.0	2.8	-0.3	1.5	1.0	1.1	1.7	-1.1	0.2	-0.2	-1.5	1.2	0.3	-0.8	0.8	-0.3
Fluid intelligence score	0.2	0.4	2.0	0.6	-0.7	-0.5	-0.6	-0.4	0.3	1.4	0.8	0.6	-0.5	0.9	0.2	-0.2	-0.5
Illnesses of siblings	0.7	0.9	2.9	1.5	-0.8	-1.7	-1.3	-1.4	0.4	0.4	1.2	1.0	-0.4	-0.5	0.3	-0.3	0.6
Neuroticism score	0.1	0.2	0.5	-0.2	-0.4	-0.5	-0.6	-0.5	0.3	-0.6	0.1	0.7	-0.2	0.2	0.3	-0.3	0.6
Weight	0.2	1.1	5.8	0.1	1.0	2.4	1.8	1.8	-0.4	0.5	-0.1	-0.5	0.3	0.0	-0.5	0.5	-1.0
Impedance of arm (right)	1.2	5.6	12.9	-0.2	-3.0	-3.5	-3.5	-3.6	2.2	-3.3	0.1	0.7	-1.8	1.6	2.2	-2.2	0.2
Arm fat percentage (right)	0.3	1.4	5.4	0.3	1.4	2.3	2.1	1.8	-0.4	0.5	0.1	-1.0	0.6	-0.4	-0.2	0.2	-1.4
Trunk fat-free mass	0.1	0.5	2.6	0.2	0.6	1.6	0.9	1.2	-0.4	0.6	0.1	0.1	0.2	-0.1	-0.7	0.7	-0.5
Hip circumference	0.7	3.0	9.6	-0.1	2.3	3.1	2.7	2.9	-1.5	1.5	-0.2	-0.8	1.2	-0.7	-1.6	1.6	-0.4
Time employed in main current job	1.7	1.9	4.4	0.8	1.9	2.0	2.1	1.8	-1.4	0.5	0.7	-0.6	1.3	-1.5	-1.4	1.4	0.2
Alcohol intake versus 10 years previously	0.7	1.0	2.8	-0.5	1.1	1.5	1.7	1.6	-0.4	0.4	-0.9	-1.6	0.4	-0.5	-0.4	0.4	-0.9
Father’s age at death	2.0	2.6	4.9	1.4	1.4	0.0	-0.3	0.8	-2.2	1.5	1.5	-1.3	2.0	-1.8	-2.2	2.2	2.1
Worrier / anxious feelings	0.5	0.9	4.5	0.2	0.6	-0.0	-0.5	0.6	-0.9	0.5	0.3	-1.3	1.1	-1.4	-0.6	0.6	2.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.5	-0.0	-1.1	-0.3	-0.8	-0.6	1.2	0.3	-0.1	-0.2	-0.9	0.5	1.2	-1.2	-0.7
Falls in the last year	0.8	1.1	2.8	0.7	-1.1	-1.7	-1.7	-1.5	0.9	-0.7	0.8	0.4	-0.2	-0.7	1.3	-1.3	0.8
Hair/balding pattern: Pattern 3	0.8	1.2	4.5	2.0	-0.1	-1.3	-0.2	-1.0	-0.0	2.0	2.1	-0.3	0.3	-1.1	0.1	-0.1	0.5
Number of live births	0.5	0.7	1.6	1.2	-0.7	-0.1	-0.2	-0.3	0.8	0.7	1.2	1.2	-0.9	-0.7	0.9	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1)	1.9	6.3	17.1	2.3	1.8	-0.2	-0.9	0.8	-3.5	0.7	2.2	-0.6	2.6	-2.6	-4.1	4.1	3.5
Pulse rate	0.5	0.8	1.7	1.3	1.2	0.7	0.5	0.7	-0.9	0.2	1.2	0.3	1.2	-1.0	-0.6	0.6	1.3
Happiness	0.7	0.9	2.7	1.2	-0.4	-1.4	-1.6	-1.2	-0.4	0.5	1.3	1.1	0.5	0.3	-0.2	0.2	0.8
Noisy workplace	0.3	0.4	1.3	1.0	-0.4	-0.5	-0.2	-0.8	0.6	-0.1	1.1	0.5	-0.5	-0.6	0.5	-0.5	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.1	-0.8	-0.3	1.1	0.9	0.3	0.4	-1.4	-0.8	-0.1	-0.9	0.8	-0.1	0.1	-0.3
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.5	8.6	0.7	2.6	2.4	2.4	2.9	-1.7	2.0	0.5	-0.1	1.8	-2.6	-1.5	1.5	0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.5	0.4	-0.1	-0.6	-0.3	-0.7	-0.2	0.3	0.4	0.4	-0.1	-0.5	-0.5	0.5	0.6
Asthma	0.3	0.7	1.5	-0.6	1.0	-0.1	0.5	0.0	-1.0	0.1	-0.7	-1.2	0.9	0.1	-1.2	1.2	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.5	-1.0	0.4	0.3	0.1	0.8	-0.3	0.6	-1.2	0.5	0.2	-0.2	-0.1	0.1	-0.3
Medication: Cholesterol lowering	1.2	1.8	4.7	1.0	2.1	1.6	1.8	2.2	-1.4	1.2	1.0	-1.1	1.5	-0.5	-0.9	0.9	-0.1
Depression (self-reported)	0.5	0.6	2.2	-0.4	0.5	1.4	1.0	1.5	0.2	1.1	-0.3	-0.2	0.1	-0.0	0.3	-0.3	-1.1
Medication: Lansoprazole	0.3	0.4	1.6	0.9	-0.1	-0.7	-0.8	-0.8	-0.3	-1.3	0.9	0.3	0.3	-0.1	0.0	-0.0	-0.1
Prospective memory result	0.6	0.8	3.1	1.6	0.7	-0.2	-0.0	0.0	-0.6	0.2	1.8	-0.3	0.9	-1.5	-0.2	0.2	1.2
Lung cancer (father)	0.2	0.3	1.2	0.8	-0.0	-0.1	-0.0	-0.4	0.1	0.3	0.9	-0.4	0.0	-1.1	0.2	-0.2	0.7
Illnesses of mother	0.2	0.3	0.8	0.4	-0.4	0.1	-0.1	-0.3	0.8	-0.3	0.3	0.7	-0.6	0.1	0.9	-0.9	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.4	18.3	2.6	1.8	-0.4	-1.5	0.6	-3.7	1.6	2.6	-0.1	2.9	-2.0	-4.2	4.2	4.3
Pulse wave Arterial Stiffness index	0.3	0.4	2.3	0.4	0.7	0.4	1.0	0.5	-0.2	-1.5	0.5	-0.2	0.3	-0.9	-0.2	0.2	-0.2
Impedance of arm (left)	1.2	5.4	11.6	-0.6	-3.0	-2.9	-2.9	-3.2	2.4	-3.4	-0.3	0.4	-2.1	1.7	2.6	-2.6	-0.3
Arm fat mass (right)	0.4	1.7	7.6	0.1	1.5	2.8	2.3	2.2	-0.5	0.6	-0.0	-1.1	0.5	-0.2	-0.6	0.6	-1.4
Trunk predicted mass	0.1	0.6	2.7	0.2	0.6	1.6	1.0	1.2	-0.5	0.5	0.1	0.1	0.3	-0.1	-0.9	0.9	-0.4
Standing height	0.4	3.7	9.0	-0.5	-3.0	-1.7	-2.6	-2.4	2.0	-2.6	-0.3	1.2	-2.2	2.2	1.5	-1.5	-0.3
Length of working week for main job	0.6	0.7	4.3	0.2	-0.9	0.4	-0.4	-0.4	0.7	-0.3	0.0	-0.0	-1.1	1.3	0.4	-0.4	-2.1
Exposure to tobacco smoke at home	2.3	2.5	6.0	0.0	-2.1	-2.4	-2.1	-2.4	1.5	-1.5	-0.0	-1.6	-1.7	0.9	1.2	-1.2	-1.2
Breastfed as a baby	0.6	0.7	1.8	0.3	-1.3	-0.9	-1.4	-1.1	0.8	-0.7	0.3	0.7	-0.9	0.2	0.8	-0.8	-0.1
Tense / ‘highly strung’	0.4	0.6	1.4	0.3	-0.8	-1.0	-1.2	-1.0	0.7	-0.3	0.5	-0.4	-0.3	-0.1	1.1	-1.1	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.9	-0.9	-0.2	0.5	0.4	0.6	0.4	1.0	-0.8	-0.5	-0.4	0.5	0.5	-0.5	-0.6
Hair/balding pattern: Pattern 4	0.2	0.6	2.0	0.6	-0.3	0.6	0.1	0.3	0.8	-1.4	0.7	-1.1	-0.6	-1.0	0.8	-0.8	-0.4
Birth weight of first child	0.1	0.3	0.9	-0.1	-0.5	0.5	0.7	0.2	0.8	-0.6	-0.1	0.2	-1.0	-0.3	0.4	-0.4	-0.3
Peak expiratory flow (PEF)	0.4	1.0	3.0	-0.1	1.0	1.7	1.5	1.6	-1.0	-0.1	-0.2	0.0	0.5	-0.4	-1.4	1.4	0.3
Pulse wave reflection index	0.4	0.5	2.2	0.2	-0.2	0.5	0.8	0.3	0.5	-1.2	0.2	-1.0	-0.8	0.1	0.1	-0.1	-1.5
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.9	-0.6	-1.2	-1.1	-1.4	-1.1	0.6	-0.4	-0.6	-0.9	-0.8	0.5	0.5	-0.5	-0.2
Loud music exposure frequency	0.1	0.1	0.5	0.7	-0.1	-0.1	-0.4	-0.1	0.1	0.5	0.6	-0.4	0.0	-0.0	0.2	-0.2	-0.1
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	3.1	-0.6	-1.8	-0.7	-1.3	-1.4	1.4	-0.1	-0.6	-0.3	-1.5	1.1	1.2	-1.2	0.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.4	0.8	-0.0	0.6	0.2	0.4	0.1	1.6	0.9	0.4	-0.0	-0.8	-0.0	0.0	-0.4
Blood clot in the leg (DVT)	0.3	0.4	1.0	0.2	0.8	0.8	0.4	0.8	-0.5	1.0	0.2	0.1	0.7	-0.9	-0.4	0.4	0.6
Medication: Paracetamol	0.1	0.2	0.6	-0.3	-0.0	-0.1	-0.6	0.3	-0.0	0.7	-0.3	-0.8	0.2	0.1	0.4	-0.4	0.3
Headache pain in last month	0.2	0.3	1.2	-0.4	-0.6	0.9	0.0	0.3	0.5	-0.3	-0.5	-1.1	-0.7	0.1	0.1	-0.1	0.4
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	4.6	0.3	-2.2	-1.9	-1.8	-2.1	1.4	-1.3	0.3	1.6	-1.7	0.2	0.8	-0.8	-0.3
Glaucoma (self-reported)	0.4	0.4	1.6	-0.2	-0.9	-0.9	-1.3	-1.3	0.3	-0.0	-0.2	0.6	-0.5	0.3	0.1	-0.1	0.3
Gout (self-reported)	0.3	0.4	2.0	-0.1	0.7	-0.5	-0.7	-0.1	-0.9	0.6	0.0	0.6	1.4	0.3	-0.4	0.4	0.5
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	10.8	0.9	1.1	0.2	-0.1	1.3	-0.8	1.8	0.5	-3.3	1.2	-2.4	-0.4	0.4	0.2
Medication: Amlodipine	0.3	0.4	1.3	-0.8	0.4	0.1	0.3	0.1	-0.6	0.2	-0.8	1.1	0.4	1.1	-0.6	0.6	0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.9	-0.3	0.1	0.1	0.4	0.1	-0.3	0.1	-0.3	-1.0	-0.0	0.2	-0.6	0.6	-0.1
Birth weight	0.4	0.9	2.0	1.4	-1.0	-1.3	-0.9	-1.0	0.7	0.3	1.4	1.4	-0.6	-0.4	0.7	-0.7	-0.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.7	-1.0	-0.5	-0.4	-0.4	-0.1	0.6	-0.9	-1.2	-1.5	-0.7	1.6	0.3	-0.3	-1.3
High blood pressure (siblings)	0.4	0.6	2.7	-0.5	0.8	1.6	1.4	1.3	-0.4	-0.3	-0.3	-0.4	0.4	-0.1	-0.3	0.3	-0.2
Forced vital capacity (FVC), Best measure	3.0	11.0	27.5	4.1	1.4	-2.2	-3.1	-0.9	-3.9	2.0	4.1	-0.1	3.2	-2.5	-4.4	4.5	5.2
Body fat percentage	0.3	1.1	4.7	0.2	1.1	2.2	1.9	1.6	-0.1	0.1	0.2	-0.9	0.3	-0.4	0.1	-0.1	-1.3
Leg fat percentage (right)	0.7	2.7	9.0	0.6	2.2	3.0	2.6	2.5	-1.1	0.9	0.5	-1.5	1.2	-1.6	-0.8	0.8	-0.8
Arm fat-free mass (right)	0.3	1.3	5.8	-0.1	1.2	2.4	1.7	2.0	-0.8	0.8	-0.2	-0.3	0.6	0.0	-1.1	1.1	-0.6
Exposure to tobacco smoke outside home	0.7	0.9	3.3	0.9	-1.1	-1.5	-1.8	-1.6	0.4	-0.4	1.1	-0.5	-0.5	-0.5	0.2	-0.2	0.3
Comparative body size at age 10	0.1	0.3	0.6	0.4	0.6	0.6	0.7	0.5	-0.4	0.2	0.6	0.8	0.6	-0.8	-0.3	0.3	0.2
Number of full brothers	0.6	0.8	2.6	0.3	1.4	1.0	1.0	1.2	-0.7	-0.4	0.6	1.6	1.2	-0.5	-0.2	0.2	-0.5
Worry too long after embarrassment	0.6	0.9	3.4	0.5	-1.0	-1.6	-1.8	-1.3	0.5	-0.5	0.7	0.9	-0.2	-0.3	0.8	-0.8	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.5	0.6	1.6	1.2	0.6	1.5	-1.4	1.6	0.5	-0.7	1.6	-1.1	-1.2	1.2	0.5
Wheeze or whistling in the chest in last year	0.3	0.5	4.0	-0.9	0.2	0.2	0.1	0.1	-0.0	0.8	-0.8	-2.0	0.1	0.3	-0.1	0.1	-0.5
Number of children fathered	0.8	0.9	2.5	-1.3	-0.3	1.1	1.1	0.7	0.5	0.9	-1.2	-1.6	-0.8	0.7	0.4	-0.4	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.7	6.9	-0.4	2.6	1.7	1.6	2.4	-2.4	1.3	-0.6	-1.9	2.3	-1.0	-2.5	2.5	1.6
Age at first live birth	0.4	0.8	3.4	0.6	0.6	-0.6	-0.5	0.1	-0.7	1.4	0.8	0.8	1.0	-1.1	-0.3	0.3	1.9
Pulse wave peak to peak time	0.5	0.6	1.8	-0.6	-1.2	-0.7	-1.4	-0.9	0.6	1.0	-0.7	0.3	-0.7	1.1	0.6	-0.6	-0.1
Health satisfaction	0.7	0.9	3.2	0.4	1.3	0.3	-0.1	0.9	-1.2	0.1	0.6	-1.8	1.4	0.0	-0.9	0.9	0.9
Shortness of breath walking on level ground	0.8	0.9	2.0	0.8	-1.2	-1.1	-1.4	-1.4	0.8	0.6	0.9	1.0	-0.7	0.5	0.9	-0.9	-0.4
Qualifications: College or University degree	0.3	1.0	5.0	-0.1	-1.4	-0.6	-1.3	-1.3	0.9	-2.2	-0.3	-0.2	-1.2	0.3	0.7	-0.7	-0.1
Eye problems/disorders: None of the above	0.2	0.2	1.0	-0.2	-0.1	0.3	0.5	-0.2	-0.1	-0.8	0.1	1.0	-0.3	0.7	-0.4	0.4	0.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	7.8	0.2	1.3	0.3	0.8	1.3	-1.3	2.8	0.2	0.4	1.2	-0.7	-1.0	1.0	0.6
Emphysema/chronic bronchitis	0.7	0.8	1.7	-0.4	-1.0	-1.3	-0.8	-1.2	1.0	-0.9	-0.2	-0.8	-0.6	0.8	1.2	-1.2	-0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.2	0.2	-0.8	-0.3	-0.3	-0.7	0.6	-0.5	0.2	1.1	-0.7	0.1	0.2	-0.2	0.1
Neck or shoulder pain in last month	1.1	1.5	4.6	-1.6	0.1	2.1	1.9	1.3	0.5	-0.2	-1.5	-2.0	-0.8	0.8	0.3	-0.3	-0.9
Medication: Blood pressure	1.1	2.0	5.7	-2.1	0.9	2.4	2.1	1.7	0.2	-0.4	-2.2	-1.0	0.1	1.1	0.6	-0.6	-1.2
Angina (self-reported)	0.9	1.2	4.2	0.2	1.6	0.9	1.1	1.4	-0.9	1.5	0.2	-2.1	1.5	-1.0	-0.2	0.2	-0.1
Migraine (self-reported)	0.6	0.7	5.2	0.7	-0.9	-0.7	-0.8	-0.9	0.7	-2.3	0.6	0.1	-0.6	-0.0	0.6	-0.6	-0.5
Medication: Ibuprofen	0.2	0.2	1.0	-0.9	-0.3	-0.1	-0.7	0.2	0.1	0.0	-1.0	0.2	-0.2	-0.0	0.3	-0.3	-0.5
Medication: Allopurinol	0.4	0.5	2.5	-0.7	1.0	-0.4	-0.5	0.2	-0.7	0.8	-0.6	0.8	1.6	0.4	-0.1	0.1	0.6
Medication: Omeprazole	0.9	1.0	2.6	0.3	0.7	1.6	1.6	1.4	-0.2	1.1	0.4	-1.5	0.1	-1.5	-0.4	0.4	-0.8
Medication: Seretide 50 evohaler	0.8	0.9	3.7	-0.2	0.7	0.6	0.8	0.3	-1.0	0.5	-0.4	-1.9	0.7	-0.3	-1.3	1.3	1.3
Mean time to correctly identify matches	0.3	0.6	2.3	0.2	0.8	0.3	0.3	0.5	-0.8	0.8	0.1	-1.5	0.7	-1.2	-0.6	0.6	0.7
Heart disease (mother)	0.8	1.0	2.6	0.9	0.9	0.0	-0.2	0.5	-1.4	1.2	1.1	-0.4	1.3	-0.4	-1.6	1.6	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.8	7.3	-1.1	-1.9	-0.1	-0.2	-0.5	2.3	-0.6	-1.1	0.2	-2.4	2.0	2.2	-2.2	-2.7
Whole body fat mass	0.3	1.3	5.8	0.2	1.2	2.4	2.0	1.8	-0.3	0.4	0.1	-0.8	0.4	-0.3	-0.1	0.1	-1.4
Leg fat mass (right)	0.5	2.1	9.1	-0.0	1.7	3.0	2.5	2.4	-0.7	0.7	-0.1	-1.1	0.7	-0.6	-0.6	0.6	-1.2
Arm predicted mass (right)	0.2	1.1	5.1	-0.2	1.0	2.3	1.6	1.9	-0.7	0.7	-0.4	-0.2	0.4	0.3	-0.9	0.9	-0.8
Pulse rate, automated reading	0.4	1.3	5.0	-0.9	0.7	2.2	2.2	1.8	0.4	-0.4	-1.0	-1.0	-0.3	0.6	0.2	-0.2	-1.4
Alcohol intake frequency.	1.2	2.8	4.8	0.1	2.2	1.7	2.0	2.0	-2.1	1.2	0.1	-1.8	1.8	-0.4	-2.2	2.2	1.3
Comparative height size at age 10	0.3	1.4	3.7	-0.6	-1.8	-0.4	-0.8	-1.3	1.4	-1.9	-0.4	1.0	-1.4	1.1	1.3	-1.3	-0.2
Number of full sisters	0.5	0.6	1.4	-0.0	-0.8	-1.2	-0.8	-0.9	0.9	0.5	-0.0	0.9	-0.6	0.2	1.1	-1.1	-0.8
Suffer from ‘nerves’	0.4	0.6	3.0	0.2	-1.0	-0.7	-0.6	-0.8	0.8	0.4	0.2	-1.7	-0.8	0.0	0.7	-0.7	-0.6
Overall health rating	0.3	0.6	1.4	0.2	1.2	0.9	0.7	1.2	0.0	0.8	0.2	-0.2	0.9	-0.2	1.0	-1.0	-1.1
Chest pain or discomfort	1.2	1.8	4.8	0.6	1.9	0.4	0.5	1.2	-1.9	1.6	0.8	-1.2	2.2	-0.8	-1.4	1.4	1.1
Had major operations	0.1	0.1	0.7	-0.1	-0.2	0.8	0.2	0.2	0.3	-0.0	-0.0	-0.3	-0.1	0.2	0.6	-0.6	0.3
Age at last live birth	0.3	0.4	1.7	-0.1	-0.3	0.1	0.1	0.3	0.8	1.1	-0.0	0.1	-0.5	-0.3	1.3	-1.3	-0.5
Family relationship satisfaction	0.4	0.5	2.6	-0.4	-0.4	0.6	0.3	-0.1	0.7	-0.4	-0.3	-0.5	-0.7	1.6	0.8	-0.8	-1.2
Leg pain on walking	4.0	5.0	10.0	0.9	2.8	0.4	1.2	1.7	-3.0	2.5	0.8	-2.9	2.7	-1.0	-3.2	3.2	2.2
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	6.4	0.7	2.0	-0.5	-0.1	0.8	-2.2	1.2	0.6	0.5	2.5	-1.0	-1.9	1.9	1.3
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.2	0.3	-2.0	-1.9	-2.1	-2.0	0.9	0.1	0.4	1.0	-1.5	1.3	0.5	-0.5	-0.2
Illness, injury, bereavement, stress in last 2 years	2.5	3.0	9.4	-2.0	-2.0	-1.7	-1.7	-2.1	1.2	-2.5	-1.9	0.1	-1.5	3.1	0.7	-0.7	-0.8
Medication: Aspirin	0.8	1.1	3.0	1.1	1.4	0.6	1.0	1.2	-1.2	1.7	1.1	-0.6	1.1	-0.3	-1.0	1.0	-0.5
Supplements: Vitamin C	0.3	0.4	1.8	-0.4	0.4	1.0	0.7	0.6	-0.6	1.3	-0.2	-0.1	0.4	-0.5	-0.6	0.6	0.3
Knee pain experienced in last month	0.2	0.3	1.5	-0.9	0.3	-0.6	-0.3	-0.1	-0.4	-0.1	-0.8	-1.2	0.5	0.6	-0.4	0.4	0.1
Hypertension (Self-reported)	1.6	4.6	9.9	-3.0	-0.2	2.7	2.7	1.3	1.4	-2.6	-3.1	-1.5	-1.4	2.3	1.3	-1.3	-2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	3.0	-0.3	-0.1	0.9	0.5	0.5	0.1	-0.6	-0.2	-1.7	-0.4	0.1	-0.2	0.2	-0.6
Illnesses of father: Heart disease	0.9	1.3	4.9	0.2	1.7	1.8	2.2	1.8	-0.5	0.6	0.2	-1.0	1.0	-0.3	0.0	-0.0	-0.7
Illnesses of siblings: Diabetes	0.5	0.7	2.4	-0.8	0.2	1.6	1.0	1.1	0.3	0.5	-1.1	-0.7	-0.4	-0.6	0.4	-0.4	-1.0
Smoking status: Previous	0.6	0.9	2.1	-0.7	-0.4	0.6	0.6	0.4	1.1	-1.4	-0.8	-0.9	-0.8	0.5	1.2	-1.2	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.0	0.4	-0.1	-0.3	-0.4	-0.1	-0.4	0.3	0.5	-0.1	0.1	1.0	-0.8	0.9	0.4
Whole body fat-free mass	0.1	0.5	2.7	-0.1	0.3	1.6	1.0	1.1	-0.0	0.3	-0.3	0.0	-0.2	0.6	-0.4	0.4	-1.0
Leg fat-free mass (right)	0.2	0.9	2.9	-0.6	-0.4	1.3	0.9	0.6	0.9	-0.3	-0.8	0.3	-1.0	1.7	0.6	-0.6	-1.6
Arm fat percentage (left)	0.4	1.6	6.9	0.1	1.4	2.6	2.4	2.0	-0.2	0.4	-0.1	-1.1	0.4	-0.4	-0.0	0.0	-1.5
Average weekly red wine intake	0.3	0.5	1.5	-1.0	-0.3	0.2	1.0	0.2	0.9	-0.2	-0.8	0.1	-0.9	1.2	0.7	-0.7	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.9	0.4	0.8	0.5	0.4	0.8	-0.4	0.9	0.2	-0.9	0.7	-0.5	0.2	-0.2	-0.6
Mood swings	0.4	0.7	4.1	-1.4	-0.3	0.3	0.3	-0.1	0.1	0.1	-1.2	2.0	-0.3	1.1	-0.1	0.1	-0.3
Loneliness, isolation	0.5	0.7	2.9	-0.1	-0.4	-1.7	-1.4	-1.0	-0.4	0.3	0.1	1.0	0.4	0.2	-0.5	0.5	1.4
Long-standing illness, disability or infirmity	1.0	1.6	13.6	-0.5	0.8	1.2	0.9	1.1	0.2	0.6	-0.7	-3.7	0.5	-1.3	0.9	-0.9	-0.4
Ever had bowel cancer screening	0.6	0.7	2.2	-0.0	-0.8	-0.7	-0.1	-0.7	1.2	-0.9	0.0	-0.1	-1.0	0.5	1.5	-1.5	-0.9
Diabetes diagnosed by doctor	1.0	1.6	4.4	-0.3	1.7	1.5	1.5	2.1	-0.8	1.4	-0.8	-2.0	1.0	-1.0	-0.3	0.3	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.7	0.3	-0.4	0.3	-0.4	-0.1	0.9	-0.0	0.2	1.4	-0.4	0.8	1.3	-1.3	-1.6
Friendships satisfaction	0.4	0.5	1.5	-0.3	-0.6	-0.2	-0.5	-0.4	0.6	0.1	-0.1	-1.2	-0.4	1.2	0.9	-0.9	-0.6
Qualifications: nursing, teaching	0.6	1.0	2.5	-0.8	-0.3	1.3	1.4	0.9	0.8	0.4	-0.7	1.1	-1.0	1.2	0.8	-0.8	-1.6
Commuting to job workplace: Walk	4.0	4.4	8.8	2.1	2.9	0.9	1.1	2.0	-2.6	2.1	1.8	-0.5	2.8	-3.0	-2.3	2.2	1.2
Eye problems/disorders: Cataract	1.9	2.2	4.4	0.1	2.1	0.8	0.9	2.1	-1.9	1.3	-0.1	-1.2	1.8	-1.9	-1.9	1.9	1.0
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.4	1.3	-0.0	-1.3	-1.1	-0.8	-0.3	0.2	1.4	0.4	0.5	-0.9	-0.1	0.1	1.5
Medication for cholesterol	0.2	0.3	1.0	-0.1	-0.5	-0.2	-0.8	-0.3	0.4	-0.1	-0.1	0.8	-0.2	0.2	0.7	-0.7	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	5.1	6.0	13.4	1.3	3.5	0.6	1.2	2.3	-3.4	1.8	1.3	-1.0	3.7	-2.9	-2.9	2.9	2.5
Back pain experienced in last month	0.6	0.9	4.0	-0.1	1.2	1.4	1.2	1.3	-0.6	0.7	-0.2	-2.0	0.9	0.4	-0.3	0.3	0.3
Mineral and other dietary supplements	0.6	0.8	2.2	-1.0	-0.2	1.0	0.6	0.5	1.0	-1.5	-1.1	-0.2	-0.8	0.2	1.1	-1.1	-0.8
Breast cancer (self-reported)	2.8	3.4	9.7	2.0	0.0	-2.9	-2.6	-1.8	-1.4	-0.0	2.2	-0.6	1.4	-1.7	-1.3	1.3	3.1
Asthma (self-reported)	0.4	0.8	1.7	-0.7	1.2	0.3	0.9	0.3	-1.1	0.1	-0.8	-1.2	1.0	0.2	-1.3	1.3	0.9
Osteoporosis (self-reported)	0.7	0.8	3.3	1.8	0.6	-0.8	-0.1	0.0	-0.7	1.1	1.6	0.5	0.6	-1.2	-0.8	0.8	0.2
Osteoarthritis (self-reported)	2.1	2.7	10.7	-0.8	2.1	1.8	1.9	1.8	-1.6	0.9	-0.8	-3.3	1.4	-0.1	-1.7	1.7	0.6
Medication: Aspirin	0.4	0.5	1.6	1.3	0.7	0.1	0.6	0.4	-0.6	0.9	1.2	-0.5	0.5	-0.3	-0.5	0.5	-1.0
Medication: Gliclazide	0.6	0.7	2.4	1.1	1.1	-0.1	-0.2	0.6	-1.0	0.7	1.0	-0.2	1.2	-1.5	-0.7	0.7	0.5
Illnesses of father: None of the above (group 1)	0.3	0.3	0.9	0.5	0.4	-0.2	-0.2	0.2	-0.6	0.8	0.5	-0.1	0.6	-0.4	-0.7	0.7	1.0
Smoking status: Current	0.2	0.4	1.0	0.3	0.9	0.4	0.7	0.7	-0.6	0.7	0.4	1.0	0.6	-0.6	-0.6	0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	5.7	12.0	23.9	2.5	3.7	1.2	0.7	2.7	-4.6	3.9	2.4	-2.5	3.9	-3.5	-4.9	4.9	4.0
Whole body water mass	0.1	0.6	2.9	-0.3	0.4	1.7	1.1	1.2	-0.1	0.2	-0.4	-0.1	-0.1	0.7	-0.5	0.5	-1.0
Leg predicted mass (right)	0.2	1.0	3.1	-0.7	-0.5	1.3	0.9	0.5	1.0	-0.5	-0.8	0.3	-1.1	1.8	0.7	-0.7	-1.7
Arm fat mass (left)	0.5	1.9	8.4	0.0	1.5	2.9	2.4	2.2	-0.6	0.7	-0.1	-1.2	0.5	-0.3	-0.6	0.6	-1.3
Number of self-reported non-cancer illnesses	1.9	3.3	7.9	-0.8	2.6	2.3	2.4	2.7	-1.7	0.9	-1.0	-2.8	2.0	-0.4	-1.4	1.4	-0.1
Average weekly champagne plus white wine intake	2.2	3.1	7.7	-0.5	-2.8	-1.3	-2.1	-2.2	2.1	-2.2	-0.2	0.9	-2.2	2.0	1.5	-1.5	-1.0
Miserableness	0.3	0.6	2.8	-1.1	-0.6	-0.0	0.1	-0.3	0.3	-0.6	-0.9	1.7	-0.6	1.2	-0.1	0.2	-0.7
Guilty feelings	0.8	1.2	4.7	-0.6	-1.4	-1.2	-1.1	-1.2	1.0	-2.2	-0.3	0.7	-1.3	1.4	0.7	-0.6	-0.1
Wears glasses or contact lenses	0.8	1.0	3.5	-1.9	-0.2	0.1	0.1	-0.2	-0.2	-1.8	-1.8	0.6	-0.4	1.1	-0.9	0.9	-0.0
Ever taken oral contraceptive pill	0.6	0.6	1.4	-0.1	-0.8	-0.3	-0.2	-0.5	1.2	-0.6	-0.1	1.0	-1.1	0.5	1.2	-1.2	-0.8
Hearing aid user	1.4	1.5	4.9	0.0	1.7	0.1	-0.1	0.6	-1.7	0.2	0.1	-0.4	2.2	-1.6	-1.3	1.3	2.1
Mother’s age at death	0.8	1.0	2.6	-0.4	-1.4	-0.3	-0.4	-0.7	1.5	0.5	-0.4	-0.1	-1.6	0.7	1.4	-1.4	-1.2
Financial situation satisfaction	1.6	2.0	4.1	1.8	1.5	0.3	-0.3	1.1	-1.5	2.0	1.8	-1.4	1.6	-1.7	-1.1	1.1	1.5
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.5	-0.0	-1.1	-1.9	-1.9	-1.7	0.8	-0.4	-0.1	1.2	-0.5	0.7	1.0	-1.0	0.4
Commuting to job workplace: Public transport	0.2	0.3	1.4	-1.0	-0.1	-0.3	0.1	0.1	0.2	-1.2	-0.8	-0.7	-0.2	0.1	0.0	-0.0	0.1
Eye problems/disorders: Glaucoma	0.4	0.5	1.5	-1.2	-0.8	-0.6	-0.8	-1.0	0.4	0.2	-1.2	0.4	-0.5	0.9	0.3	-0.3	0.3
Medication: Blood pressure	0.3	0.5	1.8	-0.8	0.5	1.1	1.2	0.7	-0.3	-1.4	-0.8	-0.7	0.0	0.5	-0.2	0.2	-0.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	3.2	-0.8	-0.6	1.2	1.1	0.2	1.3	-0.2	-0.7	-1.8	-1.2	0.8	1.5	-1.5	-1.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.9	-0.1	1.0	0.4	0.6	0.8	-1.4	1.7	-0.0	0.3	1.1	0.0	-1.5	1.5	0.1
High cholesterol (Self-reported)	1.2	2.2	5.7	-0.2	2.3	2.2	2.3	2.4	-1.3	1.4	0.0	-0.9	1.6	0.4	-1.0	1.0	0.1
Medication: Bendroflumethiazide	0.1	0.2	1.8	-0.6	0.1	-0.1	0.2	-0.4	-0.0	-0.0	-0.5	-1.3	0.1	0.6	0.0	-0.0	0.1
Medication: Paracetamol	0.2	0.2	0.9	-0.6	-0.0	0.1	-0.7	-0.1	-0.2	0.1	-0.5	-1.0	0.3	0.8	0.1	-0.1	0.7
Medication: Lisinopril	1.2	1.6	4.6	-0.8	0.9	2.1	2.1	1.6	-0.1	-0.2	-0.9	-2.1	-0.1	0.1	0.1	-0.1	-1.9
Medication: Atorvastatin	0.7	0.8	2.3	1.5	0.8	0.7	0.9	0.7	0.1	1.4	1.4	-0.1	0.3	-1.1	0.6	-0.6	-0.6
Illnesses of father: High blood pressure	3.7	4.6	7.3	1.9	2.6	1.5	1.5	2.1	-2.5	2.3	1.9	0.2	2.5	-2.7	-2.3	2.3	2.2
Alcohol drinker status: Never	0.4	0.5	2.6	-0.2	0.7	-0.2	0.3	0.2	-0.7	-0.2	-0.1	-0.6	1.0	-0.7	-0.7	0.7	1.6
Ever smoked	1.1	1.9	5.1	-1.9	-0.4	0.9	1.5	0.7	1.3	-1.4	-1.9	-0.2	-1.4	1.5	1.0	-1.0	-2.2
Basal metabolic rate	0.1	0.6	3.2	-0.1	0.4	1.8	1.1	1.2	0.0	0.3	-0.3	-0.1	-0.2	0.6	-0.3	0.3	-1.1
Leg fat percentage (left)	0.7	2.5	7.8	0.8	2.1	2.8	2.5	2.4	-1.1	1.0	0.7	-1.7	1.2	-1.5	-0.8	0.8	-0.8
Arm fat-free mass (left)	0.2	0.9	3.3	0.0	0.9	1.8	1.1	1.6	-0.8	0.8	-0.2	-0.4	0.5	0.2	-1.2	1.2	-0.5
Number of operations (self-reported)	0.1	0.2	1.1	1.0	0.2	-0.0	-0.0	-0.1	-0.2	0.6	1.0	0.0	0.3	-0.1	0.0	-0.0	0.1
Average weekly beer plus cider intake	0.8	1.2	3.0	1.3	1.3	-0.2	-0.5	0.6	-1.4	0.5	1.2	-0.5	1.7	-1.7	-1.2	1.2	0.8
Irritability	0.1	0.1	0.3	-0.5	0.5	0.5	0.5	0.3	-0.2	0.1	-0.3	0.0	0.5	0.4	0.0	-0.0	-0.0
Risk taking	0.4	0.6	2.2	0.1	-0.6	-0.7	-0.3	-0.6	0.8	-1.5	-0.0	0.8	-0.8	0.1	0.6	-0.6	-1.4
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.8	0.5	-0.7	-0.7	-0.1	-0.8	0.6	-1.3	0.9	0.2	-0.7	1.2	0.5	-0.5	-0.4
Fractured/broken bones in last 5 years	0.2	0.3	0.9	0.3	0.5	-0.3	-0.3	-0.1	-0.8	0.5	0.2	1.0	0.9	-0.2	-0.4	0.4	0.4
Age started oral contraceptive pill	1.1	1.3	3.1	-0.2	-1.8	-0.8	-0.7	-1.4	1.7	-0.6	-0.1	0.3	-1.8	1.3	1.5	-1.5	-0.3
Diastolic blood pressure, automated reading	0.4	1.3	3.9	0.0	1.1	1.8	1.6	1.5	-0.5	1.1	-0.2	-2.0	0.6	-1.3	-0.5	0.5	-0.8
Ever depressed for a whole week	0.4	0.5	2.8	-0.5	-0.3	0.0	-0.2	0.0	0.6	0.3	-0.7	-0.0	-0.5	1.0	0.8	-0.8	-1.7
Unable to work because of sickness or disability	0.2	0.3	1.1	-0.1	-0.4	-0.2	-0.3	-0.2	0.7	-0.7	-0.1	0.3	-0.3	0.3	1.0	-1.0	-1.0
Commuting to job workplace: Cycle	2.0	2.4	4.4	-1.7	-1.8	-1.1	-0.8	-1.6	1.6	-2.1	-1.7	0.9	-1.7	2.1	1.5	-1.5	-0.6
Myopia	0.9	1.2	2.6	-1.6	-0.2	1.4	1.2	0.7	1.2	-0.2	-1.6	0.4	-0.7	0.7	1.4	-1.4	-1.5
Vascular/heart problems diagnosed by doctor	1.0	2.9	6.0	2.4	-0.3	-2.4	-2.5	-1.5	-0.8	1.4	2.4	1.6	0.8	-1.7	-0.9	0.9	1.9
Cholesterol lowering medication	0.8	1.2	3.1	0.4	1.8	1.0	1.1	1.6	-1.0	1.6	0.4	-1.2	1.5	-0.7	-0.7	0.7	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.7	0.3	1.1	1.6	1.9	1.5	-0.4	0.8	0.4	-1.0	0.5	-1.3	-0.4	0.4	-0.7
Pain experienced in last month	0.8	1.3	7.8	1.4	0.4	-0.4	-0.1	-0.0	-0.7	1.7	1.3	2.8	0.4	-1.4	-0.8	0.8	0.4
Supplements: Calcium	1.6	1.7	6.5	-0.6	-1.5	-2.6	-2.2	-2.0	0.8	0.2	-0.4	0.3	-0.7	1.6	0.9	-0.9	-0.6
Basal cell carcinoma (self-reported)	0.5	0.6	2.9	0.9	0.4	-0.4	-0.2	-0.2	-0.5	0.1	1.1	1.7	0.5	-1.3	-0.5	0.5	0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.6	0.6	0.9	-0.5	-0.2	0.2	-0.8	0.9	0.8	0.6	1.3	-1.0	-0.3	0.3	0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.1	0.1	0.8	0.8	0.4	0.9	-0.5	1.1	-0.0	-0.0	0.7	-0.9	-0.5	0.5	0.6
Heart disease (siblings)	0.2	0.2	0.7	0.6	0.5	-0.0	0.2	0.2	-0.6	0.3	0.8	0.1	0.6	0.5	-0.5	0.5	-0.1
Alcohol drinker status: Previous	4.5	5.1	8.2	0.9	2.9	1.6	1.5	2.6	-2.7	2.5	0.8	-2.7	2.7	-2.1	-2.5	2.5	2.3
Pack years of smoking	0.2	0.3	1.4	-0.3	-0.2	-0.9	-1.1	-0.6	-0.3	0.1	-0.4	0.1	0.3	-0.2	-0.4	0.4	1.2
Impedance of whole body	0.7	3.4	8.3	-0.3	-2.3	-2.7	-2.8	-2.7	1.6	-2.9	-0.0	0.3	-1.4	1.0	1.8	-1.8	0.3
Leg fat mass (left)	0.5	2.1	8.7	0.0	1.8	3.0	2.5	2.4	-0.8	0.9	-0.1	-1.3	0.8	-0.6	-0.7	0.7	-1.1
Arm predicted mass (left)	0.2	1.2	3.5	0.2	1.2	1.9	1.3	1.7	-1.1	0.8	-0.1	-0.6	0.7	0.0	-1.4	1.4	-0.5