Hub : Genes

CLIC6

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1030 0.0400 6.7e-03 0.141 NA 0.107 NA 0.126 1.3e-11 NA 4.8e-09 NA 1.8e-10
2 GTEx Colon Transverse 0.2050 0.0660 3.0e-03 0.063 NA 0.032 NA 0.034 6.0e-04 NA 1.1e-02 NA 9.7e-03
3 GTEx Esophagus Gastroesophageal Junction 0.2450 0.0780 3.6e-03 0.247 NA 0.240 NA 0.240 1.9e-09 NA 3.6e-09 NA 3.4e-09
4 GTEx Esophagus Muscularis 0.1740 0.0590 4.0e-03 0.131 NA 0.121 NA 0.111 2.4e-08 NA 8.3e-08 NA 3.1e-07
5 GTEx Lung 0.1974 0.0449 3.1e-06 0.107 NA 0.112 NA 0.124 1.5e-08 NA 7.1e-09 NA 1.0e-09
6 GTEx Pituitary 0.5590 0.1010 2.1e-05 0.307 NA 0.315 NA 0.328 1.9e-08 NA 1.1e-08 NA 4.9e-09
7 GTEx Skin Sun Exposed Lower leg 0.1180 0.0440 4.0e-03 0.000 NA 0.016 NA 0.001 3.4e-01 NA 1.7e-02 NA 2.6e-01
8 METSIM Adipose 0.1795 0.0328 2.1e-12 0.168 0.097 0.150 0.153 0.168 2.0e-24 2.6e-14 9.1e-22 3.5e-22 1.9e-24
9 YFS Blood 0.0587 0.0162 4.8e-06 0.030 0.016 0.026 0.041 0.030 3.0e-10 3.2e-06 4.5e-09 2.8e-13 3.2e-10
10 TCGA Breast Invasive Carcinoma 0.0118 0.0062 4.6e-03 0.014 0.010 0.009 NA 0.011 4.7e-04 3.2e-03 3.8e-03 NA 2.2e-03
11 TCGA Glioblastoma Multiforme 0.1980 0.0950 3.0e-03 -0.004 0.073 0.056 NA 0.006 4.5e-01 3.1e-03 8.5e-03 NA 2.1e-01
12 TCGA Brain Lower Grade Glioma 0.0388 0.0184 1.4e-04 0.059 0.040 0.043 NA 0.052 2.8e-07 2.0e-05 9.9e-06 NA 1.5e-06
13 TCGA Lung Adenocarcinoma 0.0298 0.0169 2.9e-03 0.042 0.012 0.025 NA 0.033 1.0e-05 1.2e-02 6.2e-04 NA 7.7e-05
14 TCGA Stomach Adenocarcinoma 0.0610 0.0340 3.6e-03 0.006 0.025 0.019 NA 0.018 1.2e-01 5.7e-03 1.4e-02 NA 1.6e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.1 0.2 0.6 -0.7 -0.3 -0.2 -0.3 -0.3 -0.2 -0.8 -0.5 -0.0 0.1 0.1 -0.3 0.3 0.7
Bipolar Disorder or Schizophrenia 0.2 0.5 1.9 -0.6 -0.7 -0.1 0.4 0.0 0.6 0.4 -0.6 -0.2 -0.9 1.1 0.5 -0.5 -1.4
Depressed Affect (Nagel 2018) 0.3 0.7 3.4 -1.1 -0.7 -0.7 -0.2 -0.8 0.3 -1.1 -0.9 1.8 -0.6 0.9 -0.1 0.1 -0.4
Depression (Nagel 2018) 1.3 1.9 6.4 0.8 -1.1 -2.4 -2.5 -2.2 0.2 -0.7 0.9 2.4 0.1 -0.3 0.2 -0.2 0.7
Intelligence (Savage-Jansen 2018) 0.3 0.9 2.6 1.3 0.7 1.2 0.4 1.0 -0.9 1.6 1.3 -0.8 0.6 0.1 -0.9 0.9 -0.4
Neuroticism (Nagel 2018) 0.1 0.2 1.0 -0.9 0.2 -0.3 -0.2 0.1 -0.3 -0.6 -0.5 -0.0 0.4 -0.3 -0.3 0.3 1.0
Schizophrenia (2018) 0.5 1.0 5.4 -0.3 -0.6 0.0 0.8 0.3 1.0 1.2 -0.5 -0.3 -1.3 1.4 0.9 -0.9 -2.3
Schizophrenia vs Biploar Disorder 0.4 0.5 1.7 -0.0 -0.7 -0.6 -0.2 -0.4 0.8 -0.2 -0.1 1.3 -0.7 0.3 0.8 -0.8 -1.3
Worry (Nagel 2018) 0.5 1.1 4.9 0.7 0.6 -0.3 -0.5 0.3 -1.0 0.6 1.1 -1.5 1.0 -1.5 -0.9 0.9 2.2
Alzheimer’s Disease (in mother) 1.7 2.0 6.6 1.0 1.2 0.0 -0.0 0.5 -1.5 2.3 1.2 0.0 1.7 -2.0 -1.1 1.1 2.6
Alzheimer’s Disease (in father) 1.4 1.5 3.8 -1.9 -0.2 0.4 0.5 -0.1 1.0 -0.7 -1.8 1.9 -0.3 1.3 1.8 -1.8 -0.5
Alzheimer’s Disease (including proxy) 0.4 0.5 2.3 -0.4 -0.2 -0.3 -0.3 -0.7 0.4 0.5 -0.3 1.5 0.2 0.3 1.2 -1.2 0.6
Crohns Disease (2017) 0.6 1.3 3.8 -0.1 -1.7 -1.6 -1.3 -1.9 1.0 -0.0 0.0 -0.5 -1.2 2.0 0.8 -0.8 -0.5
Irritable Bowel Disease (IBD) 0.3 0.8 2.0 1.3 -0.8 -1.4 -1.3 -1.3 -0.1 0.7 1.4 -0.4 -0.3 0.8 -0.3 0.3 0.5
Ulcerative Colitis (UC) 0.7 1.3 4.1 2.0 0.5 -0.5 -0.7 -0.1 -1.2 1.3 2.0 -0.8 0.9 -0.7 -1.2 1.2 1.3
Major Depression (MDD) 0.7 0.8 2.2 -0.8 0.6 1.5 1.0 1.4 -0.4 1.2 -0.9 -0.7 0.3 0.8 -0.5 0.5 -0.9
Reaction Time 0.7 1.2 2.3 0.9 0.9 -0.4 -0.5 0.1 -1.4 1.5 0.7 -1.3 1.2 -1.4 -1.4 1.4 1.2
Verbal and Numeric Reasoning (VNR) 0.2 0.4 2.8 -0.3 -0.2 0.8 0.5 0.6 0.2 0.4 -0.1 0.2 -0.4 1.3 0.1 -0.1 -1.7
Breast Cancer 1.4 3.4 9.8 -2.2 0.4 3.1 2.8 2.2 1.5 -1.5 -2.1 -0.2 -0.7 0.3 1.9 -1.9 -1.7
Ovarian Cancer 8.1 10.7 27.1 4.6 3.2 0.1 0.0 1.7 -3.4 3.1 4.5 -1.9 3.7 -5.2 -3.2 3.2 3.3
Prostate Cancer 2.4 3.3 7.4 -2.7 -1.4 1.2 0.8 -0.1 2.0 -1.5 -2.6 -1.1 -1.9 2.5 2.0 -2.0 -1.6
Age at First Birth 0.9 1.3 3.5 -1.9 -1.3 -0.7 -0.7 -1.0 1.0 -1.1 -1.7 0.7 -1.2 1.4 0.8 -0.8 0.3
Bipolar Disorder (2011) 1.5 1.5 3.8 -1.9 -1.2 -0.7 -0.1 -1.1 1.2 -1.5 -1.7 -0.1 -1.3 1.9 0.9 -0.9 -0.3
Body Mass Index (BMI) (2010) 0.2 0.3 1.9 0.6 -0.1 0.8 0.6 0.1 0.2 0.3 0.5 0.5 -0.5 -0.1 0.1 -0.1 -1.4
Coronary Artery Disease (CAD) 0.6 0.7 3.1 0.2 -0.9 -1.8 -1.4 -1.1 0.6 0.1 0.1 0.5 -0.6 -0.6 0.6 -0.6 0.4
Crohns Disease (2012) 0.3 0.5 1.8 1.3 -0.3 -0.5 -0.6 -0.7 0.0 0.9 1.3 -1.1 -0.1 -0.4 0.2 -0.2 -0.0
Mean Putamen Volume 0.3 0.4 1.7 -0.3 0.4 0.7 0.3 1.0 0.3 -0.2 -0.2 -1.3 0.3 -0.8 0.7 -0.7 0.1
Fasting Glucose 2.3 2.8 8.2 -1.8 -0.3 2.0 2.0 1.2 1.5 -1.0 -1.9 -1.8 -1.4 1.3 1.4 -1.4 -2.9
HbA1C 0.9 1.0 2.6 -0.3 -1.6 -1.6 -1.4 -1.5 1.0 -0.1 -0.3 0.5 -1.0 0.4 1.1 -1.1 0.1
HDL Cholesterol 0.2 0.3 1.2 0.5 0.5 0.0 -0.4 0.3 -0.6 1.1 0.6 -0.5 0.8 -0.2 -0.4 0.4 0.2
LDL Cholesterol 1.2 1.9 3.3 1.2 1.6 1.8 1.4 1.6 -1.3 1.6 1.4 1.1 1.2 -1.2 -1.3 1.3 1.3
Lupus 0.6 0.8 4.4 0.7 0.7 0.4 0.3 0.7 -0.6 1.1 0.4 -2.1 0.6 -1.4 -0.7 0.7 1.0
Neuroticism (2016) 0.4 0.5 2.8 0.1 0.4 -0.3 -0.8 0.3 -0.8 1.7 0.3 -0.2 1.0 -0.4 -0.7 0.7 1.0
Primary Biliary Cirrhosis 0.6 0.9 3.2 0.2 -1.2 -1.6 -1.8 -1.3 0.4 -0.4 0.1 -1.6 -0.7 0.4 0.0 -0.0 0.1
Rheumatoid Arthritis 0.3 0.5 0.9 0.8 -0.3 -0.4 -0.2 -0.4 0.8 -0.8 0.9 -0.9 -0.3 -0.6 1.0 -1.0 -0.4
Schizophrenia (2014) 0.3 0.6 3.7 -0.4 -0.2 0.2 0.7 0.6 0.4 1.3 -0.6 0.2 -0.7 0.9 0.3 -0.3 -1.9
Triglycerides 0.3 0.4 2.3 -0.5 0.3 1.1 1.0 0.6 0.0 -0.7 -0.4 1.5 -0.3 0.4 -0.1 0.1 0.0
Type 2 Diabetes (T2D) (2012) 0.2 0.3 0.8 -0.8 -0.1 0.6 0.5 0.5 0.3 0.0 -0.9 -0.5 -0.1 -0.3 0.4 -0.4 -0.7
Ulcerative Colitis 0.6 0.9 2.2 1.3 0.7 0.8 0.7 1.0 -0.6 1.5 1.3 -1.4 0.4 -0.4 -0.9 0.9 0.3
Blood Eosinophil Count 0.2 1.3 7.9 -0.6 1.3 0.4 1.8 0.9 -0.9 2.8 -0.5 0.8 1.4 0.1 -0.4 0.4 0.7
Blood Platelet Count 0.3 2.9 9.2 -1.9 1.0 3.0 2.7 2.1 0.4 1.5 -1.9 -2.6 -0.3 0.2 0.6 -0.6 -1.2
Blood Red Count 0.1 1.1 2.9 -1.6 0.8 0.6 1.4 0.7 -0.9 1.7 -1.6 -0.6 0.9 0.0 -0.9 0.9 1.0
Blood White Count 0.4 2.7 6.2 -2.2 0.8 2.5 2.4 2.0 0.6 2.0 -2.3 -0.5 -0.1 0.5 1.1 -1.1 -2.0
Heel T-Score 0.2 1.7 4.6 2.1 -0.7 -1.0 -0.6 -1.1 1.0 1.3 2.0 1.8 -0.6 -1.5 1.3 -1.4 -0.3
BMI 0.7 4.1 9.0 -0.2 3.0 2.8 2.7 3.0 -2.1 0.9 -0.4 -1.7 2.1 -1.3 -2.1 2.1 0.5
Height 0.1 1.3 4.0 0.6 -1.7 -1.0 -1.6 -1.4 0.7 -2.0 1.0 0.5 -1.0 0.3 0.4 -0.4 1.3
Waist Hip Ratio (WHR) 0.3 1.6 6.4 -0.7 -1.3 -0.9 -1.1 -1.3 1.2 -2.5 -0.5 0.4 -1.0 1.9 1.1 -1.1 -0.7
Systolic Blood Pressure 0.1 0.5 1.6 -1.1 -0.3 0.6 0.3 -0.2 0.6 0.5 -1.3 -1.2 -0.4 0.5 0.8 -0.8 -0.1
Smoking Status 0.5 1.2 4.5 -0.7 -0.9 0.3 0.5 -0.1 1.4 -1.2 -0.7 1.1 -1.3 1.2 1.3 -1.3 -2.1
Allergy or Eczema 0.3 0.8 2.0 -0.4 1.0 -0.2 0.4 0.4 -1.4 0.4 -0.4 0.0 1.2 0.3 -1.4 1.4 1.1
Cardiovascular Disease 0.9 2.9 7.9 -2.8 0.2 2.2 2.0 1.2 0.7 -2.5 -2.8 -0.7 -0.7 2.2 0.6 -0.6 -1.2
Hypothyroidism (self reported) 0.8 1.8 8.2 0.8 1.2 0.3 0.0 1.1 -1.2 1.4 0.5 -2.9 1.4 -2.4 -0.9 0.9 1.0
Respiratory disease 0.5 1.1 5.2 -1.6 -0.5 -0.7 0.0 -1.3 0.4 -2.3 -1.4 -0.2 -0.4 1.9 0.2 -0.2 0.0
Type 2 Diabetes (T2D) (2018) 0.6 1.1 3.5 -0.0 1.4 1.5 1.3 1.9 -0.7 1.2 -0.4 -1.2 0.8 -0.7 -0.3 0.3 -0.7
Lung FEV1/FVC ratio 1.5 7.7 29.4 -2.8 2.3 5.4 5.0 4.8 -0.8 -1.6 -2.9 -0.9 0.6 0.1 -1.0 1.0 -1.7
Lung FVC 5.8 29.4 54.2 6.3 4.4 -2.5 -2.5 0.5 -6.9 5.0 6.1 -1.1 6.2 -6.5 -6.9 6.9 7.4
Neuroticism 0.3 0.6 1.8 -0.5 -1.0 -0.8 -1.0 -1.1 0.3 -1.3 -0.1 1.3 -0.7 0.7 -0.0 0.0 0.4
Chronotype (morning person) 0.2 0.5 1.9 1.4 0.4 -0.8 -0.2 -0.6 -0.5 0.6 1.1 0.6 0.6 -1.3 -0.3 0.3 0.3
Hair Pigment 0.1 2.0 5.7 0.7 1.3 -1.1 -0.5 -0.0 -1.9 0.6 0.9 -0.2 1.9 -1.6 -1.9 1.9 2.4
Tanning 0.0 0.4 1.1 0.9 0.1 0.6 0.5 0.3 -0.3 0.1 0.9 0.9 0.2 -1.0 -0.5 0.5 -0.8
Hand grip strength (left) 0.6 1.5 3.2 1.6 1.2 1.1 0.8 1.2 -1.1 0.7 1.7 1.1 1.0 -1.8 -1.2 1.2 0.6
Number of treatments/medications taken 0.3 0.5 2.9 -0.0 0.9 0.3 0.4 0.6 -0.7 0.5 0.1 -1.7 0.9 0.5 -0.3 0.3 0.2
Average weekly spirits intake 0.2 0.2 0.5 -0.6 -0.5 0.2 -0.0 -0.1 0.6 -0.1 -0.6 -0.0 -0.6 -0.1 0.7 -0.7 -0.5
Sensitivity / hurt feelings 0.5 0.9 2.6 -0.9 -0.8 -0.6 -1.3 -0.5 0.9 -1.6 -0.6 0.1 -0.3 0.2 1.3 -1.4 0.8
Frequency of depressed mood in last 2 weeks 0.8 1.1 4.2 -0.3 -0.9 -1.7 -1.8 -1.6 0.3 -0.9 -0.2 2.0 -0.2 0.7 0.1 -0.1 0.3
Hearing difficulty/problems: Yes 0.7 1.1 4.4 -0.2 -1.0 -2.1 -2.1 -1.7 0.1 0.0 -0.1 -1.3 -0.2 1.1 -0.0 0.0 0.5
Relative age of first facial hair 0.6 1.2 5.0 2.1 -0.5 -1.4 -1.4 -1.2 -0.4 0.1 2.2 -0.1 0.2 -0.2 -0.7 0.7 0.7
Other serious medical condition/disability diagnosed by doctor 1.0 1.2 4.1 -1.2 0.3 1.0 0.6 1.1 1.0 -0.0 -1.4 -0.2 -0.1 0.4 1.8 -1.8 -2.0
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.6 0.1 0.6 0.9 1.1 0.7 -0.3 0.3 0.2 -1.3 0.2 -0.1 -0.4 0.4 -0.1
Ever had hysterectomy (womb removed) 1.8 2.0 5.7 -1.4 -0.8 1.2 1.1 0.4 1.6 -1.4 -1.4 -1.5 -1.6 1.1 1.5 -1.5 -2.4
Systolic blood pressure, automated reading 0.3 0.8 4.8 -0.2 0.2 1.2 1.0 0.6 0.5 1.1 -0.3 -2.2 -0.2 -0.5 0.7 -0.7 -0.8
Eye problems/disorders: Diabetes related eye disease 0.9 0.9 2.6 1.5 0.7 -0.5 -0.3 0.5 -0.8 1.6 1.3 -1.1 1.1 -1.6 -0.4 0.4 -0.0
Angina 0.8 1.1 3.5 0.2 1.5 0.9 1.1 1.3 -0.8 1.3 0.3 -1.9 1.4 -1.0 -0.1 0.1 -0.2
Medication for hormone replacement therapy 0.1 0.2 0.8 0.3 -0.2 0.3 0.2 -0.1 0.2 -0.1 0.4 -0.7 -0.4 -0.4 -0.2 0.2 -0.9
Vitamin and mineral supplements 0.8 1.1 2.4 -1.0 -0.0 1.1 1.1 0.9 1.0 -1.5 -1.2 -1.4 -0.9 -0.1 0.9 -0.9 -1.3
Supplements: Zinc 3.0 3.3 6.5 -0.6 -2.6 -1.3 -1.6 -2.1 2.1 -2.1 -0.5 1.6 -2.2 1.8 2.0 -2.0 -1.6
Medication: Co-codamol 1.5 1.7 3.8 0.9 2.0 1.2 1.3 1.3 -1.5 1.6 0.9 -1.4 1.6 -1.2 -0.9 0.8 1.3
Medication: Metformin 1.0 1.4 3.5 -1.0 1.5 1.8 1.9 1.9 -0.4 0.5 -1.4 -1.7 0.6 -0.4 -0.0 0.0 -1.2
Diabetes (father) 0.9 1.1 3.3 -1.3 -0.7 0.7 0.0 0.1 0.9 -0.6 -1.3 1.8 -1.1 1.8 0.5 -0.5 -1.3
Diabetes (mother) 0.9 1.1 4.6 -1.4 -0.1 0.9 0.6 0.5 0.6 0.6 -1.4 -1.3 -0.7 2.1 0.6 -0.6 -1.6
Severe depression (siblings) 0.3 0.3 0.9 -0.7 -0.9 -0.0 -0.4 -0.5 0.6 0.4 -0.7 -0.4 -0.7 0.5 0.3 -0.3 -0.9
Pack years adult smoking proportion 0.2 0.3 1.4 -0.0 0.2 -0.6 -0.7 -0.2 -0.5 0.6 -0.2 0.4 0.6 -0.5 -0.5 0.5 1.2
Impedance of leg (right) 0.1 0.6 2.4 0.1 -0.5 -1.2 -1.6 -0.9 0.0 -1.2 0.3 -0.3 0.2 -0.9 0.2 -0.2 1.2
Leg fat-free mass (left) 0.2 0.9 2.9 -0.6 -0.4 1.5 1.0 0.7 0.9 -0.4 -0.7 0.3 -1.0 1.5 0.6 -0.6 -1.7
Trunk fat percentage 0.2 0.6 2.6 0.2 0.6 1.6 1.3 1.0 0.3 -0.5 0.2 -0.5 -0.1 0.0 0.6 -0.6 -1.4
Hand grip strength (right) 1.1 3.1 6.4 2.1 1.7 0.5 -0.0 1.3 -2.0 1.0 2.3 -0.1 2.0 -2.5 -2.0 2.0 2.3
Townsend deprivation index at recruitment 0.8 1.2 3.5 -1.5 0.1 0.1 0.7 0.3 0.8 -0.6 -1.7 0.5 -0.4 1.6 1.1 -1.1 -1.9
Current tobacco smoking 0.5 0.8 1.5 0.3 1.2 0.9 1.2 1.2 -0.7 1.2 0.3 1.2 0.8 -0.8 -0.6 0.6 -0.1
Average weekly fortified wine intake 1.3 1.5 4.4 2.0 -0.9 -1.8 -1.5 -1.4 0.3 1.2 2.1 0.2 -0.2 -1.3 0.5 -0.5 1.1
Maternal smoking around birth 0.3 0.4 1.7 -0.5 -0.5 -0.3 0.0 -0.3 0.5 -0.2 -0.5 1.3 -0.9 0.8 0.1 -0.1 -0.9
Fed-up feelings 0.3 0.5 6.1 -0.2 0.1 0.4 0.1 0.0 0.0 -0.2 -0.1 2.5 0.1 0.5 0.0 -0.0 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 1.6 2.1 6.9 1.3 -0.8 -2.3 -2.6 -2.0 -0.3 0.7 1.5 2.5 0.4 -0.2 -0.5 0.5 1.3
Relative age voice broke 0.6 0.9 4.0 1.9 -0.6 -1.1 -1.4 -0.6 0.0 -0.3 2.0 -0.8 -0.1 0.2 -0.1 0.1 -0.1
Taking other prescription medications 0.5 0.7 2.9 -0.3 1.1 0.7 0.8 1.2 -0.7 0.9 -0.4 -1.7 1.1 -0.5 -0.3 0.3 -0.2
Age when periods started (menarche) 0.4 1.0 1.9 -1.2 -1.4 -0.3 -0.7 -0.8 1.2 -0.7 -1.2 0.5 -1.4 1.1 0.9 -0.9 -1.0
Bilateral oophorectomy (both ovaries removed) 1.3 1.5 3.4 -0.9 -1.2 -0.3 -0.3 -0.5 1.4 -1.7 -0.7 -0.9 -1.5 1.8 1.1 -1.1 -1.9
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 4.4 2.0 0.0 -0.8 -0.7 -0.3 -0.0 2.1 1.8 0.8 0.2 -1.1 0.3 -0.3 -0.3
Tinnitus: Yes, but not now, but have in the past 0.3 0.4 1.1 -0.8 0.3 0.7 0.5 0.6 -0.4 -0.6 -0.8 -1.0 0.2 0.3 -0.7 0.7 0.1
Qualifications: CSEs or equivalent 4.2 5.6 9.0 1.7 3.0 1.9 1.9 2.5 -2.8 3.0 1.7 -0.4 2.6 -2.5 -2.8 2.8 2.2
Serious illness, injury or assault to yourself 1.6 2.0 3.7 0.6 1.8 1.9 1.9 1.9 -1.3 1.8 0.6 0.5 1.3 -1.5 -1.1 1.1 1.2
High blood pressure 1.4 4.0 9.7 -3.0 0.2 2.8 2.8 1.6 0.9 -2.1 -3.1 -1.7 -1.0 2.0 0.8 -0.8 -2.1
Hayfever, allergic rhinitis or eczema 0.1 0.3 1.1 -0.1 0.5 -0.2 0.0 0.3 -0.9 0.5 -0.2 -0.2 0.7 0.1 -1.0 1.0 0.5
Multivitamins +/- minerals 1.3 1.7 7.7 1.4 -0.1 -1.7 -1.6 -1.3 -0.7 1.1 1.6 2.8 0.7 0.3 -0.5 0.5 1.0
Stomach or abdominal pain in last month 0.8 1.0 2.1 0.7 0.6 -1.2 -0.9 -0.4 -1.1 -0.8 0.7 -1.5 1.2 -1.4 -0.9 0.9 1.4
Supplements: Glucosamine 1.5 2.0 6.1 1.2 1.5 0.6 0.5 1.0 -1.6 2.5 1.3 -1.2 1.8 -1.2 -1.4 1.4 1.5
Diverticular disease/diverticulitis (self-reported) 1.5 1.7 3.4 1.4 1.6 0.9 1.0 1.1 -1.4 1.9 1.3 0.5 1.4 -1.8 -1.5 1.5 0.5
Medication: Atenolol 0.3 0.4 2.0 0.0 -0.2 0.1 0.3 -0.1 0.6 -0.1 -0.1 -0.1 -0.3 0.4 1.0 -1.0 -1.4
Medication: Levothyroxine sodium 0.9 1.5 4.9 0.9 1.2 0.1 0.1 1.1 -1.1 1.3 0.7 -2.2 1.5 -2.2 -0.8 0.8 0.7
Sitting height 0.5 3.3 5.7 -2.3 -2.0 1.3 0.2 0.1 2.3 -1.2 -2.2 0.7 -2.4 2.4 2.0 -2.0 -1.9
Chronic bronchitis/emphysema (father) 0.9 1.0 2.5 -0.7 -1.2 -0.3 -0.8 -0.8 1.1 -1.3 -0.9 0.7 -1.1 0.7 1.1 -1.1 -1.6
High blood pressure (mother) 0.5 0.6 1.1 -1.1 0.7 0.7 0.8 1.1 -0.8 -0.2 -1.0 -0.6 0.4 -0.8 -1.1 1.1 0.3
Body mass index (BMI) 0.8 3.5 11.6 0.3 2.5 3.4 3.2 3.0 -1.2 1.7 0.1 -1.0 1.2 -1.0 -1.1 1.1 -1.1
Impedance of leg (left) 0.1 0.7 2.7 0.2 -0.5 -1.4 -1.7 -1.1 -0.1 -1.1 0.3 -0.7 0.2 -0.7 0.1 -0.1 1.3
Leg predicted mass (left) 0.2 0.9 2.8 -0.7 -0.4 1.5 1.0 0.7 0.9 -0.4 -0.8 0.2 -1.0 1.5 0.6 -0.6 -1.7
Trunk fat mass 0.2 0.7 3.7 0.2 0.7 1.9 1.5 1.3 0.1 -0.1 0.2 -0.4 0.0 -0.0 0.3 -0.3 -1.4
Waist circumference 0.5 1.9 7.2 0.1 1.8 2.7 2.3 2.3 -0.9 0.7 -0.1 -1.1 0.9 -0.2 -0.9 0.9 -0.7
Number of incorrect matches in round 0.3 0.5 1.9 -1.4 -0.4 0.2 0.3 -0.0 0.6 0.4 -1.3 -0.7 -0.4 1.2 0.6 -0.6 -0.2
Past tobacco smoking 0.5 1.0 3.6 0.8 0.2 -0.5 -0.9 -0.5 -1.0 1.6 0.9 0.6 0.9 -0.8 -1.0 1.0 1.9
Alcohol usually taken with meals 1.0 1.6 6.0 -0.6 -2.3 -0.1 -0.1 -1.3 2.0 -0.6 -0.4 0.5 -2.4 1.0 1.4 -1.4 -0.6
Nervous feelings 2.5 4.7 8.7 1.3 2.5 0.8 0.8 1.9 -2.7 2.8 1.5 -1.1 2.7 -2.6 -2.5 2.5 3.0
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 6.4 0.6 -0.4 -1.4 -1.0 -1.2 0.4 0.1 0.7 2.5 0.1 -0.7 0.5 -0.5 0.7
Hearing difficulty/problems with background noise 0.6 1.0 3.7 -0.5 -1.3 -1.9 -1.8 -1.3 0.6 -0.2 -0.2 -0.7 -0.7 1.4 0.4 -0.4 0.2
Hair/balding pattern: Pattern 2 0.7 0.9 4.0 -1.7 -0.1 0.6 0.3 0.3 0.3 -1.5 -2.0 0.4 -0.5 1.4 0.0 0.0 -0.9
Had menopause 0.6 0.7 3.4 0.2 0.7 0.7 0.9 0.8 -0.7 1.2 0.2 -1.8 0.3 -0.4 -0.9 0.9 0.2
Had other major operations 0.6 0.7 3.8 1.5 0.5 0.2 0.2 0.3 -0.2 2.0 1.5 0.3 0.3 -0.5 -0.0 0.0 -0.5
Forced vital capacity (FVC) 2.6 10.0 21.2 3.8 1.4 -2.0 -2.6 -0.7 -3.8 1.6 3.7 -0.7 2.9 -3.0 -4.6 4.6 4.6
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.5 6.3 2.5 0.6 -0.2 0.0 0.1 -0.5 1.9 2.4 0.5 0.5 -1.9 -0.4 0.4 0.3
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.5 -1.1 -0.4 -0.3 -0.6 -0.3 0.5 -0.1 -1.2 0.3 -0.3 0.7 0.5 -0.5 -0.6
Qualifications: None of the above 0.2 0.4 1.6 -1.1 0.0 -0.3 0.1 -0.0 0.2 -0.6 -1.3 -1.3 -0.1 0.2 -0.0 0.0 -0.6
Financial difficulties in last 2 years 0.2 0.3 1.6 0.7 0.3 -0.4 -0.5 0.0 -0.3 0.8 0.5 -0.7 0.4 -1.2 -0.0 0.0 0.4
Mouth/teeth dental problems 0.4 0.6 1.8 -0.6 1.0 1.0 1.0 1.1 -0.7 -0.7 -0.8 -1.4 0.6 0.0 -0.6 0.6 0.1
Heart attack 0.6 0.7 2.2 0.6 1.3 -0.2 0.1 0.4 -1.0 1.0 0.8 1.0 1.5 -1.1 -0.3 0.3 0.8
Allergy 0.3 0.7 1.4 0.1 -0.9 0.5 -0.0 -0.2 1.2 -1.0 0.2 0.8 -1.2 0.2 1.1 -1.1 -1.0
Pain all over the body in last month 1.1 1.2 4.0 0.3 1.4 0.8 0.9 1.4 -0.7 0.8 0.3 -2.0 1.4 -1.8 -0.1 0.1 0.6
Diabetes (self-reported) 0.7 1.1 4.2 -0.2 1.4 1.0 1.1 1.5 -0.8 1.3 -0.5 -2.1 0.9 -1.0 -0.5 0.5 -0.5
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.9 -1.7 0.3 0.9 0.9 0.7 -0.6 -0.8 -1.6 -0.7 0.1 0.8 -1.0 1.0 0.7
Medication: Ramipril 1.5 2.0 6.0 -1.7 0.9 2.5 2.4 1.7 0.3 -0.6 -1.8 -0.3 -0.1 1.1 0.7 -0.7 -1.8
Medication: Simvastatin 0.7 1.0 2.8 -0.3 1.5 1.0 1.1 1.7 -1.1 0.2 -0.2 -1.5 1.2 0.3 -0.8 0.8 -0.3
Fluid intelligence score 0.2 0.4 2.0 0.6 -0.7 -0.5 -0.6 -0.4 0.3 1.4 0.8 0.6 -0.5 0.9 0.2 -0.2 -0.5
Illnesses of siblings 0.7 0.9 2.9 1.5 -0.8 -1.7 -1.3 -1.4 0.4 0.4 1.2 1.0 -0.4 -0.5 0.3 -0.3 0.6
Neuroticism score 0.1 0.2 0.5 -0.2 -0.4 -0.5 -0.6 -0.5 0.3 -0.6 0.1 0.7 -0.2 0.2 0.3 -0.3 0.6
Weight 0.2 1.1 5.8 0.1 1.0 2.4 1.8 1.8 -0.4 0.5 -0.1 -0.5 0.3 0.0 -0.5 0.5 -1.0
Impedance of arm (right) 1.2 5.6 12.9 -0.2 -3.0 -3.5 -3.5 -3.6 2.2 -3.3 0.1 0.7 -1.8 1.6 2.2 -2.2 0.2
Arm fat percentage (right) 0.3 1.4 5.4 0.3 1.4 2.3 2.1 1.8 -0.4 0.5 0.1 -1.0 0.6 -0.4 -0.2 0.2 -1.4
Trunk fat-free mass 0.1 0.5 2.6 0.2 0.6 1.6 0.9 1.2 -0.4 0.6 0.1 0.1 0.2 -0.1 -0.7 0.7 -0.5
Hip circumference 0.7 3.0 9.6 -0.1 2.3 3.1 2.7 2.9 -1.5 1.5 -0.2 -0.8 1.2 -0.7 -1.6 1.6 -0.4
Time employed in main current job 1.7 1.9 4.4 0.8 1.9 2.0 2.1 1.8 -1.4 0.5 0.7 -0.6 1.3 -1.5 -1.4 1.4 0.2
Alcohol intake versus 10 years previously 0.7 1.0 2.8 -0.5 1.1 1.5 1.7 1.6 -0.4 0.4 -0.9 -1.6 0.4 -0.5 -0.4 0.4 -0.9
Father’s age at death 2.0 2.6 4.9 1.4 1.4 0.0 -0.3 0.8 -2.2 1.5 1.5 -1.3 2.0 -1.8 -2.2 2.2 2.1
Worrier / anxious feelings 0.5 0.9 4.5 0.2 0.6 -0.0 -0.5 0.6 -0.9 0.5 0.3 -1.3 1.1 -1.4 -0.6 0.6 2.1
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.5 -0.0 -1.1 -0.3 -0.8 -0.6 1.2 0.3 -0.1 -0.2 -0.9 0.5 1.2 -1.2 -0.7
Falls in the last year 0.8 1.1 2.8 0.7 -1.1 -1.7 -1.7 -1.5 0.9 -0.7 0.8 0.4 -0.2 -0.7 1.3 -1.3 0.8
Hair/balding pattern: Pattern 3 0.8 1.2 4.5 2.0 -0.1 -1.3 -0.2 -1.0 -0.0 2.0 2.1 -0.3 0.3 -1.1 0.1 -0.1 0.5
Number of live births 0.5 0.7 1.6 1.2 -0.7 -0.1 -0.2 -0.3 0.8 0.7 1.2 1.2 -0.9 -0.7 0.9 -0.9 -0.7
Forced expiratory volume in 1-second (FEV1) 1.9 6.3 17.1 2.3 1.8 -0.2 -0.9 0.8 -3.5 0.7 2.2 -0.6 2.6 -2.6 -4.1 4.1 3.5
Pulse rate 0.5 0.8 1.7 1.3 1.2 0.7 0.5 0.7 -0.9 0.2 1.2 0.3 1.2 -1.0 -0.6 0.6 1.3
Happiness 0.7 0.9 2.7 1.2 -0.4 -1.4 -1.6 -1.2 -0.4 0.5 1.3 1.1 0.5 0.3 -0.2 0.2 0.8
Noisy workplace 0.3 0.4 1.3 1.0 -0.4 -0.5 -0.2 -0.8 0.6 -0.1 1.1 0.5 -0.5 -0.6 0.5 -0.5 0.6
Qualifications: A levels/AS levels or equivalent 0.2 0.5 2.1 -0.8 -0.3 1.1 0.9 0.3 0.4 -1.4 -0.8 -0.1 -0.9 0.8 -0.1 0.1 -0.3
Serious illness, injury or assault of a close relative in last 2 years 3.1 3.5 8.6 0.7 2.6 2.4 2.4 2.9 -1.7 2.0 0.5 -0.1 1.8 -2.6 -1.5 1.5 0.6
Mouth/teeth dental problems: Dentures 0.1 0.2 0.5 0.4 -0.1 -0.6 -0.3 -0.7 -0.2 0.3 0.4 0.4 -0.1 -0.5 -0.5 0.5 0.6
Asthma 0.3 0.7 1.5 -0.6 1.0 -0.1 0.5 0.0 -1.0 0.1 -0.7 -1.2 0.9 0.1 -1.2 1.2 1.0
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 1.5 -1.0 0.4 0.3 0.1 0.8 -0.3 0.6 -1.2 0.5 0.2 -0.2 -0.1 0.1 -0.3
Medication: Cholesterol lowering 1.2 1.8 4.7 1.0 2.1 1.6 1.8 2.2 -1.4 1.2 1.0 -1.1 1.5 -0.5 -0.9 0.9 -0.1
Depression (self-reported) 0.5 0.6 2.2 -0.4 0.5 1.4 1.0 1.5 0.2 1.1 -0.3 -0.2 0.1 -0.0 0.3 -0.3 -1.1
Medication: Lansoprazole 0.3 0.4 1.6 0.9 -0.1 -0.7 -0.8 -0.8 -0.3 -1.3 0.9 0.3 0.3 -0.1 0.0 -0.0 -0.1
Prospective memory result 0.6 0.8 3.1 1.6 0.7 -0.2 -0.0 0.0 -0.6 0.2 1.8 -0.3 0.9 -1.5 -0.2 0.2 1.2
Lung cancer (father) 0.2 0.3 1.2 0.8 -0.0 -0.1 -0.0 -0.4 0.1 0.3 0.9 -0.4 0.0 -1.1 0.2 -0.2 0.7
Illnesses of mother 0.2 0.3 0.8 0.4 -0.4 0.1 -0.1 -0.3 0.8 -0.3 0.3 0.7 -0.6 0.1 0.9 -0.9 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 2.3 7.4 18.3 2.6 1.8 -0.4 -1.5 0.6 -3.7 1.6 2.6 -0.1 2.9 -2.0 -4.2 4.2 4.3
Pulse wave Arterial Stiffness index 0.3 0.4 2.3 0.4 0.7 0.4 1.0 0.5 -0.2 -1.5 0.5 -0.2 0.3 -0.9 -0.2 0.2 -0.2
Impedance of arm (left) 1.2 5.4 11.6 -0.6 -3.0 -2.9 -2.9 -3.2 2.4 -3.4 -0.3 0.4 -2.1 1.7 2.6 -2.6 -0.3
Arm fat mass (right) 0.4 1.7 7.6 0.1 1.5 2.8 2.3 2.2 -0.5 0.6 -0.0 -1.1 0.5 -0.2 -0.6 0.6 -1.4
Trunk predicted mass 0.1 0.6 2.7 0.2 0.6 1.6 1.0 1.2 -0.5 0.5 0.1 0.1 0.3 -0.1 -0.9 0.9 -0.4
Standing height 0.4 3.7 9.0 -0.5 -3.0 -1.7 -2.6 -2.4 2.0 -2.6 -0.3 1.2 -2.2 2.2 1.5 -1.5 -0.3
Length of working week for main job 0.6 0.7 4.3 0.2 -0.9 0.4 -0.4 -0.4 0.7 -0.3 0.0 -0.0 -1.1 1.3 0.4 -0.4 -2.1
Exposure to tobacco smoke at home 2.3 2.5 6.0 0.0 -2.1 -2.4 -2.1 -2.4 1.5 -1.5 -0.0 -1.6 -1.7 0.9 1.2 -1.2 -1.2
Breastfed as a baby 0.6 0.7 1.8 0.3 -1.3 -0.9 -1.4 -1.1 0.8 -0.7 0.3 0.7 -0.9 0.2 0.8 -0.8 -0.1
Tense / ‘highly strung’ 0.4 0.6 1.4 0.3 -0.8 -1.0 -1.2 -1.0 0.7 -0.3 0.5 -0.4 -0.3 -0.1 1.1 -1.1 0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 0.9 -0.9 -0.2 0.5 0.4 0.6 0.4 1.0 -0.8 -0.5 -0.4 0.5 0.5 -0.5 -0.6
Hair/balding pattern: Pattern 4 0.2 0.6 2.0 0.6 -0.3 0.6 0.1 0.3 0.8 -1.4 0.7 -1.1 -0.6 -1.0 0.8 -0.8 -0.4
Birth weight of first child 0.1 0.3 0.9 -0.1 -0.5 0.5 0.7 0.2 0.8 -0.6 -0.1 0.2 -1.0 -0.3 0.4 -0.4 -0.3
Peak expiratory flow (PEF) 0.4 1.0 3.0 -0.1 1.0 1.7 1.5 1.6 -1.0 -0.1 -0.2 0.0 0.5 -0.4 -1.4 1.4 0.3
Pulse wave reflection index 0.4 0.5 2.2 0.2 -0.2 0.5 0.8 0.3 0.5 -1.2 0.2 -1.0 -0.8 0.1 0.1 -0.1 -1.5
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.9 -0.6 -1.2 -1.1 -1.4 -1.1 0.6 -0.4 -0.6 -0.9 -0.8 0.5 0.5 -0.5 -0.2
Loud music exposure frequency 0.1 0.1 0.5 0.7 -0.1 -0.1 -0.4 -0.1 0.1 0.5 0.6 -0.4 0.0 -0.0 0.2 -0.2 -0.1
Qualifications: O levels/GCSEs or equivalent 0.7 1.2 3.1 -0.6 -1.8 -0.7 -1.3 -1.4 1.4 -0.1 -0.6 -0.3 -1.5 1.1 1.2 -1.2 0.0
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 2.4 0.8 -0.0 0.6 0.2 0.4 0.1 1.6 0.9 0.4 -0.0 -0.8 -0.0 0.0 -0.4
Blood clot in the leg (DVT) 0.3 0.4 1.0 0.2 0.8 0.8 0.4 0.8 -0.5 1.0 0.2 0.1 0.7 -0.9 -0.4 0.4 0.6
Medication: Paracetamol 0.1 0.2 0.6 -0.3 -0.0 -0.1 -0.6 0.3 -0.0 0.7 -0.3 -0.8 0.2 0.1 0.4 -0.4 0.3
Headache pain in last month 0.2 0.3 1.2 -0.4 -0.6 0.9 0.0 0.3 0.5 -0.3 -0.5 -1.1 -0.7 0.1 0.1 -0.1 0.4
Medication for cholesterol, blood pressure or diabetes 1.1 1.9 4.6 0.3 -2.2 -1.9 -1.8 -2.1 1.4 -1.3 0.3 1.6 -1.7 0.2 0.8 -0.8 -0.3
Glaucoma (self-reported) 0.4 0.4 1.6 -0.2 -0.9 -0.9 -1.3 -1.3 0.3 -0.0 -0.2 0.6 -0.5 0.3 0.1 -0.1 0.3
Gout (self-reported) 0.3 0.4 2.0 -0.1 0.7 -0.5 -0.7 -0.1 -0.9 0.6 0.0 0.6 1.4 0.3 -0.4 0.4 0.5
Hypothyroidism/myxoedema (self-reported) 1.0 1.9 10.8 0.9 1.1 0.2 -0.1 1.3 -0.8 1.8 0.5 -3.3 1.2 -2.4 -0.4 0.4 0.2
Medication: Amlodipine 0.3 0.4 1.3 -0.8 0.4 0.1 0.3 0.1 -0.6 0.2 -0.8 1.1 0.4 1.1 -0.6 0.6 0.5
Medication: Ventolin 100micrograms inhaler 0.1 0.2 0.9 -0.3 0.1 0.1 0.4 0.1 -0.3 0.1 -0.3 -1.0 -0.0 0.2 -0.6 0.6 -0.1
Birth weight 0.4 0.9 2.0 1.4 -1.0 -1.3 -0.9 -1.0 0.7 0.3 1.4 1.4 -0.6 -0.4 0.7 -0.7 -0.7
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.7 -1.0 -0.5 -0.4 -0.4 -0.1 0.6 -0.9 -1.2 -1.5 -0.7 1.6 0.3 -0.3 -1.3
High blood pressure (siblings) 0.4 0.6 2.7 -0.5 0.8 1.6 1.4 1.3 -0.4 -0.3 -0.3 -0.4 0.4 -0.1 -0.3 0.3 -0.2
Forced vital capacity (FVC), Best measure 3.0 11.0 27.5 4.1 1.4 -2.2 -3.1 -0.9 -3.9 2.0 4.1 -0.1 3.2 -2.5 -4.4 4.5 5.2
Body fat percentage 0.3 1.1 4.7 0.2 1.1 2.2 1.9 1.6 -0.1 0.1 0.2 -0.9 0.3 -0.4 0.1 -0.1 -1.3
Leg fat percentage (right) 0.7 2.7 9.0 0.6 2.2 3.0 2.6 2.5 -1.1 0.9 0.5 -1.5 1.2 -1.6 -0.8 0.8 -0.8
Arm fat-free mass (right) 0.3 1.3 5.8 -0.1 1.2 2.4 1.7 2.0 -0.8 0.8 -0.2 -0.3 0.6 0.0 -1.1 1.1 -0.6
Exposure to tobacco smoke outside home 0.7 0.9 3.3 0.9 -1.1 -1.5 -1.8 -1.6 0.4 -0.4 1.1 -0.5 -0.5 -0.5 0.2 -0.2 0.3
Comparative body size at age 10 0.1 0.3 0.6 0.4 0.6 0.6 0.7 0.5 -0.4 0.2 0.6 0.8 0.6 -0.8 -0.3 0.3 0.2
Number of full brothers 0.6 0.8 2.6 0.3 1.4 1.0 1.0 1.2 -0.7 -0.4 0.6 1.6 1.2 -0.5 -0.2 0.2 -0.5
Worry too long after embarrassment 0.6 0.9 3.4 0.5 -1.0 -1.6 -1.8 -1.3 0.5 -0.5 0.7 0.9 -0.2 -0.3 0.8 -0.8 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.4 2.5 0.6 1.6 1.2 0.6 1.5 -1.4 1.6 0.5 -0.7 1.6 -1.1 -1.2 1.2 0.5
Wheeze or whistling in the chest in last year 0.3 0.5 4.0 -0.9 0.2 0.2 0.1 0.1 -0.0 0.8 -0.8 -2.0 0.1 0.3 -0.1 0.1 -0.5
Number of children fathered 0.8 0.9 2.5 -1.3 -0.3 1.1 1.1 0.7 0.5 0.9 -1.2 -1.6 -0.8 0.7 0.4 -0.4 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 3.1 3.7 6.9 -0.4 2.6 1.7 1.6 2.4 -2.4 1.3 -0.6 -1.9 2.3 -1.0 -2.5 2.5 1.6
Age at first live birth 0.4 0.8 3.4 0.6 0.6 -0.6 -0.5 0.1 -0.7 1.4 0.8 0.8 1.0 -1.1 -0.3 0.3 1.9
Pulse wave peak to peak time 0.5 0.6 1.8 -0.6 -1.2 -0.7 -1.4 -0.9 0.6 1.0 -0.7 0.3 -0.7 1.1 0.6 -0.6 -0.1
Health satisfaction 0.7 0.9 3.2 0.4 1.3 0.3 -0.1 0.9 -1.2 0.1 0.6 -1.8 1.4 0.0 -0.9 0.9 0.9
Shortness of breath walking on level ground 0.8 0.9 2.0 0.8 -1.2 -1.1 -1.4 -1.4 0.8 0.6 0.9 1.0 -0.7 0.5 0.9 -0.9 -0.4
Qualifications: College or University degree 0.3 1.0 5.0 -0.1 -1.4 -0.6 -1.3 -1.3 0.9 -2.2 -0.3 -0.2 -1.2 0.3 0.7 -0.7 -0.1
Eye problems/disorders: None of the above 0.2 0.2 1.0 -0.2 -0.1 0.3 0.5 -0.2 -0.1 -0.8 0.1 1.0 -0.3 0.7 -0.4 0.4 0.2
Mouth/teeth dental problems: Loose teeth 1.1 1.3 7.8 0.2 1.3 0.3 0.8 1.3 -1.3 2.8 0.2 0.4 1.2 -0.7 -1.0 1.0 0.6
Emphysema/chronic bronchitis 0.7 0.8 1.7 -0.4 -1.0 -1.3 -0.8 -1.2 1.0 -0.9 -0.2 -0.8 -0.6 0.8 1.2 -1.2 -0.4
Medication for pain relief, constipation, heartburn 0.2 0.3 1.2 0.2 -0.8 -0.3 -0.3 -0.7 0.6 -0.5 0.2 1.1 -0.7 0.1 0.2 -0.2 0.1
Neck or shoulder pain in last month 1.1 1.5 4.6 -1.6 0.1 2.1 1.9 1.3 0.5 -0.2 -1.5 -2.0 -0.8 0.8 0.3 -0.3 -0.9
Medication: Blood pressure 1.1 2.0 5.7 -2.1 0.9 2.4 2.1 1.7 0.2 -0.4 -2.2 -1.0 0.1 1.1 0.6 -0.6 -1.2
Angina (self-reported) 0.9 1.2 4.2 0.2 1.6 0.9 1.1 1.4 -0.9 1.5 0.2 -2.1 1.5 -1.0 -0.2 0.2 -0.1
Migraine (self-reported) 0.6 0.7 5.2 0.7 -0.9 -0.7 -0.8 -0.9 0.7 -2.3 0.6 0.1 -0.6 -0.0 0.6 -0.6 -0.5
Medication: Ibuprofen 0.2 0.2 1.0 -0.9 -0.3 -0.1 -0.7 0.2 0.1 0.0 -1.0 0.2 -0.2 -0.0 0.3 -0.3 -0.5
Medication: Allopurinol 0.4 0.5 2.5 -0.7 1.0 -0.4 -0.5 0.2 -0.7 0.8 -0.6 0.8 1.6 0.4 -0.1 0.1 0.6
Medication: Omeprazole 0.9 1.0 2.6 0.3 0.7 1.6 1.6 1.4 -0.2 1.1 0.4 -1.5 0.1 -1.5 -0.4 0.4 -0.8
Medication: Seretide 50 evohaler 0.8 0.9 3.7 -0.2 0.7 0.6 0.8 0.3 -1.0 0.5 -0.4 -1.9 0.7 -0.3 -1.3 1.3 1.3
Mean time to correctly identify matches 0.3 0.6 2.3 0.2 0.8 0.3 0.3 0.5 -0.8 0.8 0.1 -1.5 0.7 -1.2 -0.6 0.6 0.7
Heart disease (mother) 0.8 1.0 2.6 0.9 0.9 0.0 -0.2 0.5 -1.4 1.2 1.1 -0.4 1.3 -0.4 -1.6 1.6 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.3 2.8 7.3 -1.1 -1.9 -0.1 -0.2 -0.5 2.3 -0.6 -1.1 0.2 -2.4 2.0 2.2 -2.2 -2.7
Whole body fat mass 0.3 1.3 5.8 0.2 1.2 2.4 2.0 1.8 -0.3 0.4 0.1 -0.8 0.4 -0.3 -0.1 0.1 -1.4
Leg fat mass (right) 0.5 2.1 9.1 -0.0 1.7 3.0 2.5 2.4 -0.7 0.7 -0.1 -1.1 0.7 -0.6 -0.6 0.6 -1.2
Arm predicted mass (right) 0.2 1.1 5.1 -0.2 1.0 2.3 1.6 1.9 -0.7 0.7 -0.4 -0.2 0.4 0.3 -0.9 0.9 -0.8
Pulse rate, automated reading 0.4 1.3 5.0 -0.9 0.7 2.2 2.2 1.8 0.4 -0.4 -1.0 -1.0 -0.3 0.6 0.2 -0.2 -1.4
Alcohol intake frequency. 1.2 2.8 4.8 0.1 2.2 1.7 2.0 2.0 -2.1 1.2 0.1 -1.8 1.8 -0.4 -2.2 2.2 1.3
Comparative height size at age 10 0.3 1.4 3.7 -0.6 -1.8 -0.4 -0.8 -1.3 1.4 -1.9 -0.4 1.0 -1.4 1.1 1.3 -1.3 -0.2
Number of full sisters 0.5 0.6 1.4 -0.0 -0.8 -1.2 -0.8 -0.9 0.9 0.5 -0.0 0.9 -0.6 0.2 1.1 -1.1 -0.8
Suffer from ‘nerves’ 0.4 0.6 3.0 0.2 -1.0 -0.7 -0.6 -0.8 0.8 0.4 0.2 -1.7 -0.8 0.0 0.7 -0.7 -0.6
Overall health rating 0.3 0.6 1.4 0.2 1.2 0.9 0.7 1.2 0.0 0.8 0.2 -0.2 0.9 -0.2 1.0 -1.0 -1.1
Chest pain or discomfort 1.2 1.8 4.8 0.6 1.9 0.4 0.5 1.2 -1.9 1.6 0.8 -1.2 2.2 -0.8 -1.4 1.4 1.1
Had major operations 0.1 0.1 0.7 -0.1 -0.2 0.8 0.2 0.2 0.3 -0.0 -0.0 -0.3 -0.1 0.2 0.6 -0.6 0.3
Age at last live birth 0.3 0.4 1.7 -0.1 -0.3 0.1 0.1 0.3 0.8 1.1 -0.0 0.1 -0.5 -0.3 1.3 -1.3 -0.5
Family relationship satisfaction 0.4 0.5 2.6 -0.4 -0.4 0.6 0.3 -0.1 0.7 -0.4 -0.3 -0.5 -0.7 1.6 0.8 -0.8 -1.2
Leg pain on walking 4.0 5.0 10.0 0.9 2.8 0.4 1.2 1.7 -3.0 2.5 0.8 -2.9 2.7 -1.0 -3.2 3.2 2.2
Qualifications: NVQ or HND or HNC or equivalent 1.7 2.1 6.4 0.7 2.0 -0.5 -0.1 0.8 -2.2 1.2 0.6 0.5 2.5 -1.0 -1.9 1.9 1.3
Commuting to job workplace: Car/motor vehicle 1.4 1.6 4.2 0.3 -2.0 -1.9 -2.1 -2.0 0.9 0.1 0.4 1.0 -1.5 1.3 0.5 -0.5 -0.2
Illness, injury, bereavement, stress in last 2 years 2.5 3.0 9.4 -2.0 -2.0 -1.7 -1.7 -2.1 1.2 -2.5 -1.9 0.1 -1.5 3.1 0.7 -0.7 -0.8
Medication: Aspirin 0.8 1.1 3.0 1.1 1.4 0.6 1.0 1.2 -1.2 1.7 1.1 -0.6 1.1 -0.3 -1.0 1.0 -0.5
Supplements: Vitamin C 0.3 0.4 1.8 -0.4 0.4 1.0 0.7 0.6 -0.6 1.3 -0.2 -0.1 0.4 -0.5 -0.6 0.6 0.3
Knee pain experienced in last month 0.2 0.3 1.5 -0.9 0.3 -0.6 -0.3 -0.1 -0.4 -0.1 -0.8 -1.2 0.5 0.6 -0.4 0.4 0.1
Hypertension (Self-reported) 1.6 4.6 9.9 -3.0 -0.2 2.7 2.7 1.3 1.4 -2.6 -3.1 -1.5 -1.4 2.3 1.3 -1.3 -2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 3.0 -0.3 -0.1 0.9 0.5 0.5 0.1 -0.6 -0.2 -1.7 -0.4 0.1 -0.2 0.2 -0.6
Illnesses of father: Heart disease 0.9 1.3 4.9 0.2 1.7 1.8 2.2 1.8 -0.5 0.6 0.2 -1.0 1.0 -0.3 0.0 -0.0 -0.7
Illnesses of siblings: Diabetes 0.5 0.7 2.4 -0.8 0.2 1.6 1.0 1.1 0.3 0.5 -1.1 -0.7 -0.4 -0.6 0.4 -0.4 -1.0
Smoking status: Previous 0.6 0.9 2.1 -0.7 -0.4 0.6 0.6 0.4 1.1 -1.4 -0.8 -0.9 -0.8 0.5 1.2 -1.2 -1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 1.0 0.4 -0.1 -0.3 -0.4 -0.1 -0.4 0.3 0.5 -0.1 0.1 1.0 -0.8 0.9 0.4
Whole body fat-free mass 0.1 0.5 2.7 -0.1 0.3 1.6 1.0 1.1 -0.0 0.3 -0.3 0.0 -0.2 0.6 -0.4 0.4 -1.0
Leg fat-free mass (right) 0.2 0.9 2.9 -0.6 -0.4 1.3 0.9 0.6 0.9 -0.3 -0.8 0.3 -1.0 1.7 0.6 -0.6 -1.6
Arm fat percentage (left) 0.4 1.6 6.9 0.1 1.4 2.6 2.4 2.0 -0.2 0.4 -0.1 -1.1 0.4 -0.4 -0.0 0.0 -1.5
Average weekly red wine intake 0.3 0.5 1.5 -1.0 -0.3 0.2 1.0 0.2 0.9 -0.2 -0.8 0.1 -0.9 1.2 0.7 -0.7 -0.1
Handedness (chirality/laterality): Left-handed 0.3 0.3 0.9 0.4 0.8 0.5 0.4 0.8 -0.4 0.9 0.2 -0.9 0.7 -0.5 0.2 -0.2 -0.6
Mood swings 0.4 0.7 4.1 -1.4 -0.3 0.3 0.3 -0.1 0.1 0.1 -1.2 2.0 -0.3 1.1 -0.1 0.1 -0.3
Loneliness, isolation 0.5 0.7 2.9 -0.1 -0.4 -1.7 -1.4 -1.0 -0.4 0.3 0.1 1.0 0.4 0.2 -0.5 0.5 1.4
Long-standing illness, disability or infirmity 1.0 1.6 13.6 -0.5 0.8 1.2 0.9 1.1 0.2 0.6 -0.7 -3.7 0.5 -1.3 0.9 -0.9 -0.4
Ever had bowel cancer screening 0.6 0.7 2.2 -0.0 -0.8 -0.7 -0.1 -0.7 1.2 -0.9 0.0 -0.1 -1.0 0.5 1.5 -1.5 -0.9
Diabetes diagnosed by doctor 1.0 1.6 4.4 -0.3 1.7 1.5 1.5 2.1 -0.8 1.4 -0.8 -2.0 1.0 -1.0 -0.3 0.3 -0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 2.7 0.3 -0.4 0.3 -0.4 -0.1 0.9 -0.0 0.2 1.4 -0.4 0.8 1.3 -1.3 -1.6
Friendships satisfaction 0.4 0.5 1.5 -0.3 -0.6 -0.2 -0.5 -0.4 0.6 0.1 -0.1 -1.2 -0.4 1.2 0.9 -0.9 -0.6
Qualifications: nursing, teaching 0.6 1.0 2.5 -0.8 -0.3 1.3 1.4 0.9 0.8 0.4 -0.7 1.1 -1.0 1.2 0.8 -0.8 -1.6
Commuting to job workplace: Walk 4.0 4.4 8.8 2.1 2.9 0.9 1.1 2.0 -2.6 2.1 1.8 -0.5 2.8 -3.0 -2.3 2.2 1.2
Eye problems/disorders: Cataract 1.9 2.2 4.4 0.1 2.1 0.8 0.9 2.1 -1.9 1.3 -0.1 -1.2 1.8 -1.9 -1.9 1.9 1.0
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.4 1.3 -0.0 -1.3 -1.1 -0.8 -0.3 0.2 1.4 0.4 0.5 -0.9 -0.1 0.1 1.5
Medication for cholesterol 0.2 0.3 1.0 -0.1 -0.5 -0.2 -0.8 -0.3 0.4 -0.1 -0.1 0.8 -0.2 0.2 0.7 -0.7 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 5.1 6.0 13.4 1.3 3.5 0.6 1.2 2.3 -3.4 1.8 1.3 -1.0 3.7 -2.9 -2.9 2.9 2.5
Back pain experienced in last month 0.6 0.9 4.0 -0.1 1.2 1.4 1.2 1.3 -0.6 0.7 -0.2 -2.0 0.9 0.4 -0.3 0.3 0.3
Mineral and other dietary supplements 0.6 0.8 2.2 -1.0 -0.2 1.0 0.6 0.5 1.0 -1.5 -1.1 -0.2 -0.8 0.2 1.1 -1.1 -0.8
Breast cancer (self-reported) 2.8 3.4 9.7 2.0 0.0 -2.9 -2.6 -1.8 -1.4 -0.0 2.2 -0.6 1.4 -1.7 -1.3 1.3 3.1
Asthma (self-reported) 0.4 0.8 1.7 -0.7 1.2 0.3 0.9 0.3 -1.1 0.1 -0.8 -1.2 1.0 0.2 -1.3 1.3 0.9
Osteoporosis (self-reported) 0.7 0.8 3.3 1.8 0.6 -0.8 -0.1 0.0 -0.7 1.1 1.6 0.5 0.6 -1.2 -0.8 0.8 0.2
Osteoarthritis (self-reported) 2.1 2.7 10.7 -0.8 2.1 1.8 1.9 1.8 -1.6 0.9 -0.8 -3.3 1.4 -0.1 -1.7 1.7 0.6
Medication: Aspirin 0.4 0.5 1.6 1.3 0.7 0.1 0.6 0.4 -0.6 0.9 1.2 -0.5 0.5 -0.3 -0.5 0.5 -1.0
Medication: Gliclazide 0.6 0.7 2.4 1.1 1.1 -0.1 -0.2 0.6 -1.0 0.7 1.0 -0.2 1.2 -1.5 -0.7 0.7 0.5
Illnesses of father: None of the above (group 1) 0.3 0.3 0.9 0.5 0.4 -0.2 -0.2 0.2 -0.6 0.8 0.5 -0.1 0.6 -0.4 -0.7 0.7 1.0
Smoking status: Current 0.2 0.4 1.0 0.3 0.9 0.4 0.7 0.7 -0.6 0.7 0.4 1.0 0.6 -0.6 -0.6 0.6 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 5.7 12.0 23.9 2.5 3.7 1.2 0.7 2.7 -4.6 3.9 2.4 -2.5 3.9 -3.5 -4.9 4.9 4.0
Whole body water mass 0.1 0.6 2.9 -0.3 0.4 1.7 1.1 1.2 -0.1 0.2 -0.4 -0.1 -0.1 0.7 -0.5 0.5 -1.0
Leg predicted mass (right) 0.2 1.0 3.1 -0.7 -0.5 1.3 0.9 0.5 1.0 -0.5 -0.8 0.3 -1.1 1.8 0.7 -0.7 -1.7
Arm fat mass (left) 0.5 1.9 8.4 0.0 1.5 2.9 2.4 2.2 -0.6 0.7 -0.1 -1.2 0.5 -0.3 -0.6 0.6 -1.3
Number of self-reported non-cancer illnesses 1.9 3.3 7.9 -0.8 2.6 2.3 2.4 2.7 -1.7 0.9 -1.0 -2.8 2.0 -0.4 -1.4 1.4 -0.1
Average weekly champagne plus white wine intake 2.2 3.1 7.7 -0.5 -2.8 -1.3 -2.1 -2.2 2.1 -2.2 -0.2 0.9 -2.2 2.0 1.5 -1.5 -1.0
Miserableness 0.3 0.6 2.8 -1.1 -0.6 -0.0 0.1 -0.3 0.3 -0.6 -0.9 1.7 -0.6 1.2 -0.1 0.2 -0.7
Guilty feelings 0.8 1.2 4.7 -0.6 -1.4 -1.2 -1.1 -1.2 1.0 -2.2 -0.3 0.7 -1.3 1.4 0.7 -0.6 -0.1
Wears glasses or contact lenses 0.8 1.0 3.5 -1.9 -0.2 0.1 0.1 -0.2 -0.2 -1.8 -1.8 0.6 -0.4 1.1 -0.9 0.9 -0.0
Ever taken oral contraceptive pill 0.6 0.6 1.4 -0.1 -0.8 -0.3 -0.2 -0.5 1.2 -0.6 -0.1 1.0 -1.1 0.5 1.2 -1.2 -0.8
Hearing aid user 1.4 1.5 4.9 0.0 1.7 0.1 -0.1 0.6 -1.7 0.2 0.1 -0.4 2.2 -1.6 -1.3 1.3 2.1
Mother’s age at death 0.8 1.0 2.6 -0.4 -1.4 -0.3 -0.4 -0.7 1.5 0.5 -0.4 -0.1 -1.6 0.7 1.4 -1.4 -1.2
Financial situation satisfaction 1.6 2.0 4.1 1.8 1.5 0.3 -0.3 1.1 -1.5 2.0 1.8 -1.4 1.6 -1.7 -1.1 1.1 1.5
Tinnitus: Yes, now most or all of the time 1.0 1.2 3.5 -0.0 -1.1 -1.9 -1.9 -1.7 0.8 -0.4 -0.1 1.2 -0.5 0.7 1.0 -1.0 0.4
Commuting to job workplace: Public transport 0.2 0.3 1.4 -1.0 -0.1 -0.3 0.1 0.1 0.2 -1.2 -0.8 -0.7 -0.2 0.1 0.0 -0.0 0.1
Eye problems/disorders: Glaucoma 0.4 0.5 1.5 -1.2 -0.8 -0.6 -0.8 -1.0 0.4 0.2 -1.2 0.4 -0.5 0.9 0.3 -0.3 0.3
Medication: Blood pressure 0.3 0.5 1.8 -0.8 0.5 1.1 1.2 0.7 -0.3 -1.4 -0.8 -0.7 0.0 0.5 -0.2 0.2 -0.4
Pain type(s) experienced in last month: Hip pain 1.0 1.3 3.2 -0.8 -0.6 1.2 1.1 0.2 1.3 -0.2 -0.7 -1.8 -1.2 0.8 1.5 -1.5 -1.5
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.9 -0.1 1.0 0.4 0.6 0.8 -1.4 1.7 -0.0 0.3 1.1 0.0 -1.5 1.5 0.1
High cholesterol (Self-reported) 1.2 2.2 5.7 -0.2 2.3 2.2 2.3 2.4 -1.3 1.4 0.0 -0.9 1.6 0.4 -1.0 1.0 0.1
Medication: Bendroflumethiazide 0.1 0.2 1.8 -0.6 0.1 -0.1 0.2 -0.4 -0.0 -0.0 -0.5 -1.3 0.1 0.6 0.0 -0.0 0.1
Medication: Paracetamol 0.2 0.2 0.9 -0.6 -0.0 0.1 -0.7 -0.1 -0.2 0.1 -0.5 -1.0 0.3 0.8 0.1 -0.1 0.7
Medication: Lisinopril 1.2 1.6 4.6 -0.8 0.9 2.1 2.1 1.6 -0.1 -0.2 -0.9 -2.1 -0.1 0.1 0.1 -0.1 -1.9
Medication: Atorvastatin 0.7 0.8 2.3 1.5 0.8 0.7 0.9 0.7 0.1 1.4 1.4 -0.1 0.3 -1.1 0.6 -0.6 -0.6
Illnesses of father: High blood pressure 3.7 4.6 7.3 1.9 2.6 1.5 1.5 2.1 -2.5 2.3 1.9 0.2 2.5 -2.7 -2.3 2.3 2.2
Alcohol drinker status: Never 0.4 0.5 2.6 -0.2 0.7 -0.2 0.3 0.2 -0.7 -0.2 -0.1 -0.6 1.0 -0.7 -0.7 0.7 1.6
Ever smoked 1.1 1.9 5.1 -1.9 -0.4 0.9 1.5 0.7 1.3 -1.4 -1.9 -0.2 -1.4 1.5 1.0 -1.0 -2.2
Basal metabolic rate 0.1 0.6 3.2 -0.1 0.4 1.8 1.1 1.2 0.0 0.3 -0.3 -0.1 -0.2 0.6 -0.3 0.3 -1.1
Leg fat percentage (left) 0.7 2.5 7.8 0.8 2.1 2.8 2.5 2.4 -1.1 1.0 0.7 -1.7 1.2 -1.5 -0.8 0.8 -0.8
Arm fat-free mass (left) 0.2 0.9 3.3 0.0 0.9 1.8 1.1 1.6 -0.8 0.8 -0.2 -0.4 0.5 0.2 -1.2 1.2 -0.5
Number of operations (self-reported) 0.1 0.2 1.1 1.0 0.2 -0.0 -0.0 -0.1 -0.2 0.6 1.0 0.0 0.3 -0.1 0.0 -0.0 0.1
Average weekly beer plus cider intake 0.8 1.2 3.0 1.3 1.3 -0.2 -0.5 0.6 -1.4 0.5 1.2 -0.5 1.7 -1.7 -1.2 1.2 0.8
Irritability 0.1 0.1 0.3 -0.5 0.5 0.5 0.5 0.3 -0.2 0.1 -0.3 0.0 0.5 0.4 0.0 -0.0 -0.0
Risk taking 0.4 0.6 2.2 0.1 -0.6 -0.7 -0.3 -0.6 0.8 -1.5 -0.0 0.8 -0.8 0.1 0.6 -0.6 -1.4
Ever had prostate specific antigen (PSA) test 0.5 0.5 1.8 0.5 -0.7 -0.7 -0.1 -0.8 0.6 -1.3 0.9 0.2 -0.7 1.2 0.5 -0.5 -0.4
Fractured/broken bones in last 5 years 0.2 0.3 0.9 0.3 0.5 -0.3 -0.3 -0.1 -0.8 0.5 0.2 1.0 0.9 -0.2 -0.4 0.4 0.4
Age started oral contraceptive pill 1.1 1.3 3.1 -0.2 -1.8 -0.8 -0.7 -1.4 1.7 -0.6 -0.1 0.3 -1.8 1.3 1.5 -1.5 -0.3
Diastolic blood pressure, automated reading 0.4 1.3 3.9 0.0 1.1 1.8 1.6 1.5 -0.5 1.1 -0.2 -2.0 0.6 -1.3 -0.5 0.5 -0.8
Ever depressed for a whole week 0.4 0.5 2.8 -0.5 -0.3 0.0 -0.2 0.0 0.6 0.3 -0.7 -0.0 -0.5 1.0 0.8 -0.8 -1.7
Unable to work because of sickness or disability 0.2 0.3 1.1 -0.1 -0.4 -0.2 -0.3 -0.2 0.7 -0.7 -0.1 0.3 -0.3 0.3 1.0 -1.0 -1.0
Commuting to job workplace: Cycle 2.0 2.4 4.4 -1.7 -1.8 -1.1 -0.8 -1.6 1.6 -2.1 -1.7 0.9 -1.7 2.1 1.5 -1.5 -0.6
Myopia 0.9 1.2 2.6 -1.6 -0.2 1.4 1.2 0.7 1.2 -0.2 -1.6 0.4 -0.7 0.7 1.4 -1.4 -1.5
Vascular/heart problems diagnosed by doctor 1.0 2.9 6.0 2.4 -0.3 -2.4 -2.5 -1.5 -0.8 1.4 2.4 1.6 0.8 -1.7 -0.9 0.9 1.9
Cholesterol lowering medication 0.8 1.2 3.1 0.4 1.8 1.0 1.1 1.6 -1.0 1.6 0.4 -1.2 1.5 -0.7 -0.7 0.7 -0.0
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 3.7 0.3 1.1 1.6 1.9 1.5 -0.4 0.8 0.4 -1.0 0.5 -1.3 -0.4 0.4 -0.7
Pain experienced in last month 0.8 1.3 7.8 1.4 0.4 -0.4 -0.1 -0.0 -0.7 1.7 1.3 2.8 0.4 -1.4 -0.8 0.8 0.4
Supplements: Calcium 1.6 1.7 6.5 -0.6 -1.5 -2.6 -2.2 -2.0 0.8 0.2 -0.4 0.3 -0.7 1.6 0.9 -0.9 -0.6
Basal cell carcinoma (self-reported) 0.5 0.6 2.9 0.9 0.4 -0.4 -0.2 -0.2 -0.5 0.1 1.1 1.7 0.5 -1.3 -0.5 0.5 0.5
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.6 0.6 0.9 -0.5 -0.2 0.2 -0.8 0.9 0.8 0.6 1.3 -1.0 -0.3 0.3 0.8
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.1 0.1 0.8 0.8 0.4 0.9 -0.5 1.1 -0.0 -0.0 0.7 -0.9 -0.5 0.5 0.6
Heart disease (siblings) 0.2 0.2 0.7 0.6 0.5 -0.0 0.2 0.2 -0.6 0.3 0.8 0.1 0.6 0.5 -0.5 0.5 -0.1
Alcohol drinker status: Previous 4.5 5.1 8.2 0.9 2.9 1.6 1.5 2.6 -2.7 2.5 0.8 -2.7 2.7 -2.1 -2.5 2.5 2.3
Pack years of smoking 0.2 0.3 1.4 -0.3 -0.2 -0.9 -1.1 -0.6 -0.3 0.1 -0.4 0.1 0.3 -0.2 -0.4 0.4 1.2
Impedance of whole body 0.7 3.4 8.3 -0.3 -2.3 -2.7 -2.8 -2.7 1.6 -2.9 -0.0 0.3 -1.4 1.0 1.8 -1.8 0.3
Leg fat mass (left) 0.5 2.1 8.7 0.0 1.8 3.0 2.5 2.4 -0.8 0.9 -0.1 -1.3 0.8 -0.6 -0.7 0.7 -1.1
Arm predicted mass (left) 0.2 1.2 3.5 0.2 1.2 1.9 1.3 1.7 -1.1 0.8 -0.1 -0.6 0.7 0.0 -1.4 1.4 -0.5