[Hub]/) : Traits : Lung FVC : ← →

chr5:77,052,232-79,318,982

Best TWAS P=1.22e-10 · Best GWAS P=6.88e-15 conditioned to 3.07e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DMGDH 0.13 0.13 bslmm 465 0.13 2.9e-15 6.4 5.5 4.3e-08 0.01 0.00 1.00 FALSE
2 GTEx Cells Transformed fibroblasts DMGDH 0.15 0.14 lasso 3 0.13 9.8e-10 6.0 5.9 2.7e-09 0.02 0.02 0.98 FALSE
3 GTEx Testis JMY 0.11 0.12 lasso 1 0.10 4.9e-05 6.1 6.1 1.4e-09 0.01 0.01 0.98 FALSE
4 NTR Blood JMY 0.02 0.01 lasso 1 0.01 2.5e-03 6.2 6.2 4.2e-10 0.02 0.01 0.98 TRUE
5 ROSMAP Brain Pre-frontal Cortex DMGDH 0.10 0.08 enet 28 0.08 3.0e-10 6.0 5.4 7.2e-08 0.05 0.02 0.98 FALSE
6 ROSMAP Brain Pre-frontal Cortex BHMT2 0.10 0.03 blup 404 0.06 8.9e-08 -2.2 5.1 3.0e-07 0.05 0.82 0.18 FALSE
7 YFS Blood JMY 0.05 0.07 lasso 4 0.07 1.3e-20 6.0 6.0 1.8e-09 0.01 0.03 0.97 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma AP3B1 0.02 0.00 blup 126 0.01 1.8e-02 -7.7 -6.4 1.2e-10 0.85 0.02 0.86 TRUE
9 The Cancer Genome Atlas Colon Adenocarcinoma JMY 0.06 0.09 blup 51 0.09 4.0e-06 6.0 5.2 2.2e-07 0.00 0.02 0.98 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AP3B1 0.08 0.01 enet 20 0.02 9.7e-04 -7.8 -5.3 1.3e-07 0.60 0.01 0.86 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma JMY 0.05 0.03 blup 52 0.02 1.0e-03 6.1 5.9 3.1e-09 0.02 0.02 0.97 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma AP3B1 0.05 0.02 blup 126 0.03 5.0e-04 2.5 -6.1 1.1e-09 0.81 0.02 0.92 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma BHMT 0.05 0.03 blup 40 0.04 9.8e-05 5.2 5.3 1.5e-07 0.05 0.01 0.98 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma JMY 0.05 0.04 enet 5 0.04 2.1e-04 5.5 5.4 7.8e-08 0.00 0.05 0.92 FALSE