Best TWAS P=2.59e-15 · Best GWAS P=2.51e-39 conditioned to 3.64e-38
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | DSP | 0.33 | 0.23 | lasso | 4 | 0.23 | 1.9e-17 | -5.6 | 5.9 | 4.0e-09 | 0.05 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Whole Blood | RIOK1 | 0.08 | 0.06 | enet | 26 | 0.05 | 1.6e-05 | -3.4 | 6.2 | 5.0e-10 | -0.13 | 0.90 | 0.01 | TRUE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | BMP6 | 0.29 | 0.00 | blup | 162 | 0.03 | 5.6e-02 | -1.8 | -7.9 | 2.6e-15 | -0.03 | 0.02 | 0.05 | TRUE |