[Hub]/) : Traits : Lung FVC :

chr6:157,713,662-159,884,002

Best TWAS P=9.81e-13 · Best GWAS P=1.22e-13 conditioned to 0.755

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TULP4 0.16 0.08 bslmm 596 0.12 2.9e-14 -7.4 -5.6 2.1e-08 0.74 0.00 1.00 FALSE
2 GTEx Artery Aorta SNX9 0.14 0.00 lasso 3 0.00 1.9e-01 6.1 5.4 5.3e-08 -0.61 0.15 0.23 FALSE
3 GTEx Brain Cerebellar Hemisphere TULP4 0.44 0.37 lasso 12 0.32 4.3e-09 7.2 7.1 9.8e-13 -0.92 0.02 0.98 TRUE
4 GTEx Brain Cerebellum TULP4 0.46 0.32 lasso 15 0.28 7.6e-09 6.4 6.5 7.4e-11 -0.83 0.26 0.73 FALSE
5 GTEx Colon Transverse MIR3918 0.12 -0.01 enet 24 0.00 2.8e-01 4.4 5.6 2.8e-08 -0.23 0.07 0.19 TRUE
6 GTEx Esophagus Mucosa TULP4 0.38 0.28 enet 37 0.29 1.2e-19 6.7 -5.7 1.3e-08 0.69 0.24 0.76 FALSE
7 GTEx Thyroid TULP4 0.09 0.02 lasso 4 0.03 1.4e-03 6.1 5.3 8.9e-08 -0.76 0.02 0.87 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TULP4 0.09 0.05 blup 148 0.04 2.0e-05 5.9 -6.2 4.8e-10 0.54 0.68 0.13 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma TULP4 0.03 0.03 lasso 3 0.02 5.1e-03 7.1 -7.1 1.3e-12 0.91 0.01 0.95 FALSE