Best TWAS P=9.81e-13 · Best GWAS P=1.22e-13 conditioned to 0.755
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TULP4 | 0.16 | 0.08 | bslmm | 596 | 0.12 | 2.9e-14 | -7.4 | -5.6 | 2.1e-08 | 0.74 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | SNX9 | 0.14 | 0.00 | lasso | 3 | 0.00 | 1.9e-01 | 6.1 | 5.4 | 5.3e-08 | -0.61 | 0.15 | 0.23 | FALSE |
| 3 | GTEx | Brain Cerebellar Hemisphere | TULP4 | 0.44 | 0.37 | lasso | 12 | 0.32 | 4.3e-09 | 7.2 | 7.1 | 9.8e-13 | -0.92 | 0.02 | 0.98 | TRUE |
| 4 | GTEx | Brain Cerebellum | TULP4 | 0.46 | 0.32 | lasso | 15 | 0.28 | 7.6e-09 | 6.4 | 6.5 | 7.4e-11 | -0.83 | 0.26 | 0.73 | FALSE |
| 5 | GTEx | Colon Transverse | MIR3918 | 0.12 | -0.01 | enet | 24 | 0.00 | 2.8e-01 | 4.4 | 5.6 | 2.8e-08 | -0.23 | 0.07 | 0.19 | TRUE |
| 6 | GTEx | Esophagus Mucosa | TULP4 | 0.38 | 0.28 | enet | 37 | 0.29 | 1.2e-19 | 6.7 | -5.7 | 1.3e-08 | 0.69 | 0.24 | 0.76 | FALSE |
| 7 | GTEx | Thyroid | TULP4 | 0.09 | 0.02 | lasso | 4 | 0.03 | 1.4e-03 | 6.1 | 5.3 | 8.9e-08 | -0.76 | 0.02 | 0.87 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 2.0e-05 | 5.9 | -6.2 | 4.8e-10 | 0.54 | 0.68 | 0.13 | TRUE |
| 9 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TULP4 | 0.03 | 0.03 | lasso | 3 | 0.02 | 5.1e-03 | 7.1 | -7.1 | 1.3e-12 | 0.91 | 0.01 | 0.95 | FALSE |