[Hub]/) : Traits : Fasting Glucose : →

chr2:26,592,429-29,260,106

Best TWAS P=9.3e-24 · Best GWAS P=4.23e-25 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	GTF3C2	0.06	0.09	lasso	8	0.08	7.2e-10	6.18	-7.4	1.5e-13	0.75	0.61	0.39	FALSE
2	CommonMind	Brain Pre-frontal Cortex	IFT172	0.06	0.09	enet	16	0.09	3.9e-11	5.75	8.6	6.3e-18	-0.78	0.83	0.17	FALSE
3	GTEx	Adipose Subcutaneous	NRBP1	0.07	0.04	lasso	5	0.05	6.9e-05	5.67	-5.4	8.1e-08	0.56	0.94	0.00	FALSE
4	GTEx	Adipose Subcutaneous	PPM1G	0.04	0.05	lasso	2	0.04	4.9e-04	5.60	-5.2	1.5e-07	0.61	0.60	0.02	FALSE
5	GTEx	Adipose Subcutaneous	AC074117.10	0.06	0.04	lasso	5	0.02	4.8e-03	7.08	-5.8	9.1e-09	0.66	0.60	0.03	FALSE
6	GTEx	Adipose Visceral Omentum	NRBP1	0.05	0.05	lasso	4	0.04	2.5e-03	5.60	-5.8	5.7e-09	0.63	0.34	0.05	FALSE
7	GTEx	Adipose Visceral Omentum	PPM1G	0.06	0.01	lasso	5	0.01	1.1e-01	5.60	-6.4	2.0e-10	0.66	0.15	0.04	TRUE
8	GTEx	Adipose Visceral Omentum	KRTCAP3	0.10	0.07	lasso	4	0.06	5.2e-04	6.18	6.2	6.1e-10	-0.64	0.73	0.04	FALSE
9	GTEx	Adipose Visceral Omentum	AC074117.10	0.14	0.09	lasso	3	0.08	5.0e-05	5.49	-5.7	9.7e-09	0.62	0.91	0.01	FALSE
10	GTEx	Adrenal Gland	KHK	0.24	0.13	enet	22	0.22	1.6e-08	4.27	6.6	5.2e-11	-0.28	0.77	0.09	FALSE
11	GTEx	Adrenal Gland	KRTCAP3	0.11	0.16	lasso	4	0.15	4.9e-06	5.21	5.5	4.3e-08	-0.63	0.81	0.08	FALSE
12	GTEx	Artery Aorta	AC074117.10	0.06	0.04	lasso	3	0.03	6.8e-03	5.49	-5.4	7.9e-08	0.60	0.27	0.04	FALSE
13	GTEx	Artery Coronary	NRBP1	0.09	0.01	enet	14	0.03	4.4e-02	4.03	-5.7	1.4e-08	0.49	0.24	0.04	FALSE
14	GTEx	Artery Coronary	AC074117.10	0.13	0.17	enet	9	0.12	5.4e-05	4.07	-5.2	1.7e-07	0.49	0.30	0.20	FALSE
15	GTEx	Artery Tibial	PPM1G	0.06	0.02	lasso	4	0.03	2.3e-03	6.22	-6.4	1.4e-10	0.70	0.32	0.03	FALSE
16	GTEx	Artery Tibial	AC074117.10	0.13	0.14	lasso	5	0.13	1.1e-10	5.49	-6.2	7.5e-10	0.64	1.00	0.00	FALSE
17	GTEx	Brain Cerebellum	AC074117.10	0.13	0.08	enet	6	0.07	4.4e-03	6.07	6.0	2.1e-09	-0.63	0.16	0.10	FALSE
18	GTEx	Breast Mammary Tissue (Female)	ABHD1	0.17	0.01	enet	28	0.07	5.3e-03	2.34	7.5	7.6e-14	-0.51	0.02	0.66	FALSE
19	GTEx	Cells EBV-transformed lymphocytes	NRBP1	0.11	0.13	enet	13	0.15	1.2e-05	5.23	-6.0	2.5e-09	0.64	0.60	0.05	FALSE
20	GTEx	Cells Transformed fibroblasts	NRBP1	0.09	0.08	lasso	3	0.08	7.8e-07	5.46	-6.2	5.7e-10	0.63	0.99	0.00	FALSE
21	GTEx	Cells Transformed fibroblasts	IFT172	0.04	0.04	lasso	2	0.02	8.1e-03	5.50	5.5	4.5e-08	-0.64	0.25	0.09	FALSE
22	GTEx	Cells Transformed fibroblasts	AC074117.10	0.21	0.19	enet	23	0.18	1.6e-13	7.08	-6.2	5.6e-10	0.65	1.00	0.00	FALSE
23	GTEx	Colon Sigmoid	AC074117.10	0.13	0.18	lasso	3	0.14	1.1e-05	5.49	-5.7	1.1e-08	0.62	0.92	0.01	FALSE
24	GTEx	Colon Transverse	NRBP1	0.08	0.03	enet	14	0.00	2.0e-01	6.63	-5.3	1.5e-07	0.62	0.17	0.11	FALSE
25	GTEx	Esophagus Gastroesophageal Junction	NRBP1	0.11	0.01	enet	23	0.02	7.7e-02	4.94	-5.3	1.0e-07	0.56	0.15	0.04	FALSE
26	GTEx	Esophagus Gastroesophageal Junction	KHK	0.16	0.11	enet	16	0.09	3.6e-04	4.53	5.5	3.3e-08	-0.14	0.81	0.02	TRUE
27	GTEx	Esophagus Gastroesophageal Junction	AC074117.10	0.12	0.13	enet	9	0.09	4.9e-04	6.00	-7.1	1.0e-12	0.66	0.59	0.04	FALSE
28	GTEx	Esophagus Mucosa	AC074117.10	0.12	0.14	lasso	8	0.14	2.1e-09	7.08	-6.7	2.8e-11	0.74	0.98	0.02	FALSE
29	GTEx	Esophagus Muscularis	NRBP1	0.07	0.04	lasso	6	0.04	1.3e-03	7.08	-9.4	7.5e-21	0.81	0.44	0.19	FALSE
30	GTEx	Esophagus Muscularis	AC074117.10	0.17	0.14	enet	5	0.09	6.6e-06	7.08	-6.7	1.8e-11	0.66	0.97	0.02	FALSE
31	GTEx	Lung	NRBP1	0.05	0.05	enet	9	0.05	1.7e-04	6.22	-5.6	2.7e-08	0.64	0.88	0.01	FALSE
32	GTEx	Lung	AC074117.10	0.07	0.06	lasso	6	0.05	6.6e-05	6.22	-6.5	6.0e-11	0.66	0.97	0.03	FALSE
33	GTEx	Muscle Skeletal	SNX17	0.18	0.24	lasso	6	0.26	6.2e-26	5.84	-5.9	2.8e-09	0.64	1.00	0.00	FALSE
34	GTEx	Muscle Skeletal	KRTCAP3	0.08	0.06	lasso	4	0.04	3.1e-05	5.32	5.5	3.6e-08	-0.61	1.00	0.00	FALSE
35	GTEx	Nerve Tibial	NRBP1	0.06	0.00	enet	9	0.02	2.0e-02	7.08	-6.5	9.3e-11	0.63	0.71	0.02	FALSE
36	GTEx	Nerve Tibial	PPM1G	0.09	0.06	lasso	4	0.05	1.2e-04	5.62	-5.3	9.0e-08	0.59	0.67	0.03	FALSE
37	GTEx	Ovary	AC074117.10	0.16	0.04	enet	9	0.05	2.0e-02	5.60	-7.4	1.0e-13	0.79	0.14	0.31	FALSE
38	GTEx	Pituitary	AC074117.10	0.23	0.23	lasso	8	0.29	5.6e-08	5.62	-7.5	7.1e-14	0.69	0.50	0.37	FALSE
39	GTEx	Prostate	KHK	0.18	0.01	lasso	4	0.06	1.4e-02	3.80	5.5	4.9e-08	-0.08	0.13	0.07	FALSE
40	GTEx	Prostate	AC074117.10	0.14	0.01	lasso	5	0.02	8.8e-02	7.08	-5.9	4.4e-09	0.63	0.12	0.18	FALSE
41	GTEx	Skin Not Sun Exposed Suprapubic	NRBP1	0.19	0.15	lasso	7	0.16	6.0e-09	6.22	-5.7	9.8e-09	0.60	1.00	0.00	FALSE
42	GTEx	Skin Sun Exposed Lower leg	NRBP1	0.10	0.08	lasso	6	0.08	3.6e-07	6.00	-5.7	1.2e-08	0.60	1.00	0.00	FALSE
43	GTEx	Skin Sun Exposed Lower leg	ATRAID	0.14	0.07	enet	15	0.09	1.3e-07	3.59	5.4	8.1e-08	-0.42	0.96	0.04	FALSE
44	GTEx	Skin Sun Exposed Lower leg	SLC4A1AP	0.04	0.01	lasso	3	0.02	1.7e-02	5.34	5.9	3.5e-09	-0.61	0.21	0.12	FALSE
45	GTEx	Stomach	AC074117.10	0.06	0.01	lasso	7	0.01	7.8e-02	7.08	5.5	4.6e-08	-0.35	0.20	0.04	FALSE
46	GTEx	Testis	NRBP1	0.16	0.09	lasso	3	0.06	1.8e-03	7.08	-8.1	4.2e-16	0.82	0.42	0.39	FALSE
47	GTEx	Testis	AC074117.10	0.14	0.08	lasso	6	0.12	4.5e-06	1.28	-6.0	1.9e-09	0.88	0.14	0.85	FALSE
48	GTEx	Testis	RP11-195B17.1	0.13	0.00	lasso	4	0.02	4.5e-02	6.22	-5.8	6.1e-09	0.60	0.05	0.13	FALSE
49	GTEx	Thyroid	FNDC4	0.24	0.10	enet	23	0.16	2.2e-12	4.62	7.0	2.9e-12	-0.71	0.66	0.34	TRUE
50	GTEx	Thyroid	PPM1G	0.06	0.06	lasso	3	0.06	2.2e-05	5.60	-5.7	1.3e-08	0.62	0.93	0.00	FALSE
51	GTEx	Thyroid	AC074117.10	0.17	0.14	lasso	4	0.15	2.7e-11	6.00	-6.1	9.0e-10	0.63	1.00	0.00	FALSE
52	GTEx	Vagina	AC074117.10	0.14	0.04	enet	13	0.06	1.4e-02	4.91	-5.5	3.4e-08	0.74	0.16	0.14	FALSE
53	GTEx	Whole Blood	KHK	0.05	0.06	lasso	5	0.02	4.6e-03	5.33	6.0	2.0e-09	-0.29	0.52	0.21	FALSE
54	GTEx	Whole Blood	KRTCAP3	0.12	0.05	enet	10	0.05	9.9e-06	5.66	5.8	8.9e-09	-0.66	0.98	0.00	FALSE
55	METSIM	Adipose	BRE	0.03	0.00	blup	534	0.00	1.3e-01	0.12	-5.5	4.9e-08	0.30	0.10	0.08	FALSE
56	METSIM	Adipose	NRBP1	0.06	0.09	lasso	3	0.08	1.6e-12	7.08	-7.1	1.5e-12	0.68	1.00	0.00	FALSE
57	METSIM	Adipose	SLC5A6	0.03	0.02	bslmm	298	0.01	3.9e-03	4.70	-6.3	2.8e-10	0.46	0.24	0.10	FALSE
58	NTR	Blood	CGREF1	0.01	0.00	blup	307	0.01	5.7e-03	3.91	6.8	7.6e-12	-0.52	0.19	0.12	FALSE
59	ROSMAP	Brain Pre-frontal Cortex	SNX17	0.27	0.35	lasso	10	0.34	7.9e-46	5.83	5.9	4.0e-09	-0.63	1.00	0.00	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	CGREF1	0.06	0.04	blup	307	0.06	2.6e-08	4.91	6.2	5.1e-10	-0.24	1.00	0.00	FALSE
61	ROSMAP	Brain Pre-frontal Cortex	FTH1P3	0.04	0.01	bslmm	280	0.02	2.8e-03	7.08	-6.0	1.6e-09	0.67	0.15	0.03	TRUE
62	YFS	Blood	EIF2B4	0.01	0.00	enet	9	0.00	8.5e-02	3.98	6.0	1.5e-09	-0.55	0.04	0.07	FALSE
63	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPM1G	0.03	0.02	blup	31	0.02	8.8e-03	6.07	-6.1	1.0e-09	0.68	0.02	0.76	FALSE
64	The Cancer Genome Atlas	Breast Invasive Carcinoma	KRTCAP3	0.01	0.00	blup	27	0.00	8.7e-02	4.91	5.7	1.6e-08	-0.58	0.03	0.52	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	NRBP1	0.03	0.03	blup	29	0.03	1.2e-06	5.08	-6.2	6.4e-10	0.60	0.26	0.73	FALSE
66	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CGREF1	0.11	0.03	blup	37	0.02	2.6e-02	3.11	5.2	2.5e-07	-0.11	0.01	0.08	FALSE
67	The Cancer Genome Atlas	Colon Adenocarcinoma	NRBP1	0.03	0.04	lasso	1	0.03	5.2e-03	5.73	-5.7	9.9e-09	0.61	0.02	0.64	FALSE
68	The Cancer Genome Atlas	Glioblastoma Multiforme	NRBP1	0.15	0.10	lasso	2	0.10	5.8e-04	7.08	-7.1	1.7e-12	0.67	0.00	0.81	FALSE
69	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IFT172	0.02	0.01	blup	43	0.02	2.7e-03	5.08	-5.4	6.2e-08	0.62	0.10	0.12	FALSE
70	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	KRTCAP3	0.02	0.01	blup	28	0.01	2.9e-02	5.71	5.6	2.1e-08	-0.59	0.03	0.63	FALSE
71	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NRBP1	0.06	0.07	lasso	2	0.07	1.1e-08	5.74	-5.7	9.5e-09	0.62	0.23	0.77	FALSE
72	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SNX17	0.02	0.01	blup	26	0.01	2.1e-02	5.86	6.1	1.3e-09	-0.64	0.03	0.82	FALSE
73	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SUPT7L	0.05	0.02	blup	28	0.04	5.2e-05	4.78	6.0	1.8e-09	-0.41	0.03	0.84	FALSE
74	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FNDC4	0.13	0.06	lasso	2	0.05	1.1e-03	-10.12	10.0	9.3e-24	-0.95	0.00	0.92	TRUE
75	The Cancer Genome Atlas	Brain Lower Grade Glioma	CGREF1	0.02	0.01	blup	37	0.02	2.3e-03	3.75	5.2	2.6e-07	-0.10	0.10	0.18	FALSE
76	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPM1G	0.03	0.03	blup	32	0.02	9.3e-04	5.86	-5.3	1.1e-07	0.59	0.27	0.28	FALSE
77	The Cancer Genome Atlas	Lung Adenocarcinoma	NRBP1	0.03	0.05	blup	30	0.05	3.7e-06	5.72	-5.5	4.0e-08	0.61	0.18	0.82	FALSE
78	The Cancer Genome Atlas	Prostate Adenocarcinoma	NRBP1	0.03	0.03	blup	30	0.03	2.2e-04	4.91	-6.1	1.4e-09	0.65	0.03	0.96	FALSE
79	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPM1G	0.03	0.02	blup	32	0.02	2.4e-03	6.19	-6.1	1.3e-09	0.63	0.02	0.89	FALSE
80	The Cancer Genome Atlas	Thyroid Carcinoma	FNDC4	0.24	0.09	enet	9	0.17	1.9e-16	4.79	7.3	2.6e-13	-0.69	0.48	0.52	FALSE
81	The Cancer Genome Atlas	Thyroid Carcinoma	GCKR	0.18	0.08	enet	5	0.13	1.7e-12	4.62	6.4	1.3e-10	-0.67	0.86	0.14	FALSE
82	The Cancer Genome Atlas	Thyroid Carcinoma	NRBP1	0.03	0.01	blup	30	0.02	5.3e-03	7.08	-6.2	4.4e-10	0.64	0.01	0.96	FALSE