[Hub]/) : Traits : Heel T-Score : ← →

chr1:112,241,795-115,222,434

Best TWAS P=3.37e-51 · Best GWAS P=1.26e-55 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LRIG2	0.05	0.01	bslmm	358	0.03	1.0e-04	-0.79	5.1	2.9e-07	0.19	0.15	0.10	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PPM1J	0.05	0.01	bslmm	322	0.01	1.6e-02	5.36	9.5	2.0e-21	0.18	0.10	0.03	FALSE
3	CommonMind	Brain Pre-frontal Cortex	ST7L	0.25	0.33	bslmm	401	0.34	3.4e-43	8.11	10.6	4.3e-26	0.48	1.00	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	WNT2B	0.43	0.46	enet	44	0.47	7.4e-64	14.65	14.4	2.8e-47	0.69	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	ST7L	0.27	0.32	enet	17	0.34	2.6e-28	8.08	9.7	2.0e-22	0.45	1.00	0.00	FALSE
6	GTEx	Adipose Subcutaneous	CAPZA1	0.09	0.06	lasso	3	0.05	5.0e-05	8.04	8.1	4.6e-16	0.37	0.92	0.00	FALSE
7	GTEx	Adipose Visceral Omentum	ST7L	0.33	0.32	enet	29	0.32	4.2e-17	8.07	12.2	4.5e-34	0.56	1.00	0.00	TRUE
8	GTEx	Adrenal Gland	ST7L	0.37	0.40	lasso	5	0.40	1.5e-15	8.07	8.2	2.4e-16	0.40	1.00	0.00	FALSE
9	GTEx	Adrenal Gland	RP4-671G15.2	0.17	0.12	lasso	4	0.08	6.7e-04	5.36	5.2	1.9e-07	0.00	0.13	0.10	FALSE
10	GTEx	Artery Aorta	ST7L	0.34	0.38	enet	17	0.37	1.6e-21	8.07	8.5	2.0e-17	0.40	1.00	0.00	FALSE
11	GTEx	Artery Coronary	ST7L	0.43	0.33	enet	12	0.20	2.0e-07	8.04	8.1	4.5e-16	0.36	1.00	0.00	FALSE
12	GTEx	Artery Tibial	ST7L	0.22	0.21	enet	13	0.21	3.8e-16	8.07	10.3	9.0e-25	0.49	1.00	0.00	FALSE
13	GTEx	Artery Tibial	CAPZA1	0.08	0.01	enet	26	0.00	1.8e-01	8.04	5.4	6.1e-08	0.18	0.19	0.03	FALSE
14	GTEx	Brain Caudate basal ganglia	ST7L	0.19	0.14	lasso	2	0.12	1.9e-04	8.11	8.1	5.2e-16	0.36	0.25	0.05	FALSE
15	GTEx	Brain Cerebellar Hemisphere	ST7L	0.24	0.16	lasso	2	0.12	5.1e-04	7.76	9.5	1.5e-21	0.50	0.06	0.39	FALSE
16	GTEx	Brain Cerebellum	RP4-671G15.2	0.25	0.25	lasso	5	0.21	6.3e-07	8.07	-8.1	4.6e-16	-0.37	0.94	0.01	FALSE
17	GTEx	Brain Cortex	ST7L	0.29	0.18	lasso	5	0.20	3.1e-06	8.07	11.1	1.5e-28	0.53	0.32	0.29	FALSE
18	GTEx	Brain Cortex	CAPZA1	0.21	0.16	lasso	6	0.11	6.7e-04	8.12	7.6	4.1e-14	0.33	0.19	0.04	FALSE
19	GTEx	Brain Cortex	WNT2B	0.36	0.19	lasso	5	0.23	5.5e-07	14.61	15.0	1.0e-50	0.80	0.02	0.97	FALSE
20	GTEx	Brain Frontal Cortex BA9	WNT2B	0.29	0.28	lasso	3	0.29	2.6e-08	14.61	15.1	3.4e-51	0.82	0.04	0.96	TRUE
21	GTEx	Brain Nucleus accumbens basal ganglia	ST7L	0.31	0.10	lasso	7	0.05	2.1e-02	-8.89	9.7	4.8e-22	0.34	0.10	0.19	FALSE
22	GTEx	Breast Mammary Tissue	ST7L	0.25	0.30	enet	11	0.31	1.9e-16	8.10	8.3	1.5e-16	0.38	1.00	0.00	FALSE
23	GTEx	Breast Mammary Tissue (Male)	ST7L	0.23	0.20	lasso	7	0.14	4.9e-04	7.76	8.0	1.4e-15	0.37	0.20	0.07	FALSE
24	GTEx	Breast Mammary Tissue (Female)	ST7L	0.33	0.27	lasso	3	0.26	3.0e-08	7.76	8.1	7.9e-16	0.39	0.96	0.01	FALSE
25	GTEx	Cells EBV-transformed lymphocytes	ST7L	0.33	0.20	enet	30	0.14	2.1e-05	8.07	6.8	1.1e-11	0.31	0.79	0.02	FALSE
26	GTEx	Cells Transformed fibroblasts	ST7L	0.54	0.64	enet	13	0.66	1.3e-64	8.07	10.0	2.3e-23	0.48	1.00	0.00	FALSE
27	GTEx	Cells Transformed fibroblasts	CTTNBP2NL	0.15	0.16	enet	7	0.19	5.4e-14	5.58	5.8	7.6e-09	-0.04	1.00	0.00	FALSE
28	GTEx	Colon Transverse	ST7L	0.22	0.19	enet	9	0.16	3.4e-08	8.07	9.5	1.7e-21	0.47	1.00	0.00	FALSE
29	GTEx	Esophagus Gastroesophageal Junction	ST7L	0.32	0.30	enet	31	0.30	1.9e-11	8.07	10.5	8.6e-26	0.44	1.00	0.00	FALSE
30	GTEx	Esophagus Mucosa	ST7L	0.18	0.20	lasso	3	0.19	8.9e-13	8.07	9.7	2.4e-22	0.47	1.00	0.00	FALSE
31	GTEx	Esophagus Muscularis	ST7L	0.26	0.33	lasso	5	0.33	1.4e-20	7.76	8.1	8.3e-16	0.39	1.00	0.00	TRUE
32	GTEx	Esophagus Muscularis	OLFML3	0.30	0.24	lasso	3	0.23	2.8e-14	5.69	-6.0	2.3e-09	0.04	0.09	0.91	TRUE
33	GTEx	Esophagus Muscularis	CTTNBP2NL	0.14	0.06	lasso	6	0.03	8.6e-03	6.50	7.1	1.6e-12	-0.02	0.52	0.02	FALSE
34	GTEx	Heart Atrial Appendage	ST7L	0.25	0.08	enet	18	0.11	1.1e-05	8.08	11.7	7.8e-32	0.56	0.82	0.16	FALSE
35	GTEx	Heart Left Ventricle	ST7L	0.12	0.13	lasso	3	0.12	5.2e-07	8.07	8.2	3.7e-16	0.38	0.92	0.01	FALSE
36	GTEx	Lung	ST7L	0.18	0.25	lasso	4	0.25	4.5e-19	8.10	8.2	3.6e-16	0.37	1.00	0.00	FALSE
37	GTEx	Muscle Skeletal	ST7L	0.04	0.05	enet	6	0.02	4.3e-03	8.11	8.2	2.1e-16	0.38	0.94	0.00	FALSE
38	GTEx	Nerve Tibial	ST7L	0.27	0.36	enet	24	0.32	1.4e-23	8.11	7.8	7.3e-15	0.33	1.00	0.00	FALSE
39	GTEx	Ovary	ST7L	0.53	0.05	enet	33	0.15	1.7e-04	-8.52	11.8	3.4e-32	0.33	0.12	0.08	FALSE
40	GTEx	Ovary	PPM1J	0.48	0.00	lasso	9	0.01	1.4e-01	2.86	6.2	7.6e-10	0.14	0.04	0.07	TRUE
41	GTEx	Pancreas	ST7L	0.25	0.17	enet	21	0.24	1.1e-10	8.11	7.3	3.2e-13	0.40	0.98	0.00	FALSE
42	GTEx	Pituitary	ST7L	0.31	0.18	lasso	7	0.18	3.0e-05	14.72	14.8	2.6e-49	0.86	0.01	0.98	FALSE
43	GTEx	Skin Not Sun Exposed Suprapubic	ST7L	0.14	0.10	enet	8	0.06	2.6e-04	8.08	11.1	8.6e-29	0.53	0.76	0.20	FALSE
44	GTEx	Skin Not Sun Exposed Suprapubic	SLC16A1	0.12	0.00	lasso	5	0.04	5.0e-03	14.61	-14.1	4.5e-45	-0.74	0.01	0.95	FALSE
45	GTEx	Skin Sun Exposed Lower leg	ST7L	0.12	0.12	lasso	1	0.11	1.7e-09	8.10	8.1	5.4e-16	0.36	1.00	0.00	FALSE
46	GTEx	Skin Sun Exposed Lower leg	MOV10	0.05	0.02	lasso	5	0.02	1.1e-02	14.61	14.2	1.1e-45	0.85	0.01	0.97	FALSE
47	GTEx	Small Intestine Terminal Ileum	ST7L	0.34	0.15	lasso	6	0.11	1.9e-03	-8.52	8.6	8.6e-18	0.33	0.09	0.12	FALSE
48	GTEx	Stomach	ST7L	0.21	0.24	lasso	3	0.23	2.6e-11	8.14	10.0	1.5e-23	0.47	1.00	0.00	FALSE
49	GTEx	Testis	ST7L	0.46	0.55	lasso	6	0.55	7.4e-29	8.07	8.7	2.8e-18	0.42	1.00	0.00	FALSE
50	GTEx	Testis	RLIMP2	0.35	0.00	enet	47	0.06	1.1e-03	-0.74	-6.6	3.2e-11	-0.32	0.18	0.08	FALSE
51	GTEx	Thyroid	ST7L	0.15	0.20	lasso	2	0.19	1.4e-14	8.07	8.1	6.4e-16	0.38	1.00	0.00	FALSE
52	GTEx	Uterus	ST7L	0.20	-0.01	enet	13	-0.01	8.0e-01	8.08	5.8	6.7e-09	0.19	0.07	0.06	TRUE
53	GTEx	Whole Blood	ST7L	0.09	0.08	lasso	2	0.08	1.5e-07	8.08	8.1	4.9e-16	0.38	1.00	0.00	FALSE
54	METSIM	Adipose	ST7L	0.22	0.25	enet	11	0.25	1.0e-37	8.08	9.9	4.5e-23	0.50	1.00	0.00	FALSE
55	NTR	Blood	ST7L	0.02	0.01	enet	18	0.01	5.1e-03	8.07	8.1	4.8e-16	0.37	0.82	0.03	FALSE
56	ROSMAP	Brain Pre-frontal Cortex	WNT2B	0.34	0.40	enet	30	0.42	1.5e-59	14.61	14.8	2.6e-49	0.77	1.00	0.00	FALSE
57	YFS	Blood	MOV10	0.07	0.04	blup	314	0.04	1.5e-12	14.57	11.7	1.1e-31	0.59	1.00	0.00	FALSE
58	YFS	Blood	ST7L	0.09	0.10	lasso	8	0.10	2.4e-32	8.07	8.2	3.4e-16	0.38	1.00	0.00	FALSE
59	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ST7L	0.21	0.22	blup	56	0.21	1.7e-17	8.07	10.5	8.1e-26	0.42	1.00	0.00	FALSE
60	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	WNT2B	0.10	0.04	blup	46	0.03	2.7e-03	6.43	12.9	7.3e-38	0.36	0.60	0.06	FALSE
61	The Cancer Genome Atlas	Breast Invasive Carcinoma	ST7L	0.23	0.36	lasso	5	0.36	2.8e-76	8.07	9.1	7.2e-20	0.44	1.00	0.00	FALSE
62	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ST7L	0.09	0.00	blup	56	0.01	7.2e-02	8.07	6.6	3.9e-11	0.20	0.03	0.04	FALSE
63	The Cancer Genome Atlas	Colon Adenocarcinoma	ST7L	0.33	0.19	lasso	3	0.21	1.7e-12	8.07	11.4	3.0e-30	0.57	1.00	0.00	FALSE
64	The Cancer Genome Atlas	Glioblastoma Multiforme	ST7L	0.27	0.20	blup	55	0.18	5.0e-06	8.14	9.7	4.7e-22	0.44	0.55	0.13	FALSE
65	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ST7L	0.13	0.17	lasso	3	0.17	1.5e-18	8.07	8.2	1.8e-16	0.39	1.00	0.00	FALSE
66	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTTNBP2NL	0.04	0.00	blup	53	0.02	2.1e-03	8.34	8.4	3.6e-17	0.27	0.04	0.15	FALSE
67	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ST7L	0.18	0.27	blup	56	0.28	2.4e-31	8.09	10.4	3.7e-25	0.57	1.00	0.00	FALSE
68	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ST7L	0.14	0.09	enet	11	0.13	6.5e-08	8.08	8.6	5.9e-18	0.40	1.00	0.00	FALSE
69	The Cancer Genome Atlas	Brain Lower Grade Glioma	ST7L	0.21	0.36	lasso	6	0.37	1.7e-43	8.07	8.1	6.3e-16	0.38	1.00	0.00	FALSE
70	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ST7L	0.23	0.24	lasso	2	0.22	7.4e-11	8.07	7.5	4.3e-14	0.35	1.00	0.00	FALSE
71	The Cancer Genome Atlas	Lung Adenocarcinoma	ST7L	0.26	0.35	enet	17	0.36	2.6e-43	8.07	9.8	1.6e-22	0.50	1.00	0.00	FALSE
72	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ST7L	0.05	0.09	lasso	2	0.08	1.4e-09	8.07	8.3	1.4e-16	0.37	1.00	0.00	FALSE
73	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ST7L	0.12	0.18	enet	12	0.17	9.3e-12	8.07	8.2	2.3e-16	0.39	1.00	0.00	FALSE
74	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	WNT2B	0.05	0.02	blup	46	0.05	4.7e-04	-4.47	-8.1	7.0e-16	-0.40	0.06	0.07	TRUE
75	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ST7L	0.39	0.36	lasso	7	0.35	1.8e-15	8.07	8.8	9.3e-19	0.42	1.00	0.00	FALSE
76	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ST7L	0.28	0.28	enet	12	0.26	1.0e-10	8.08	9.5	1.7e-21	0.46	1.00	0.00	FALSE
77	The Cancer Genome Atlas	Prostate Adenocarcinoma	CTTNBP2NL	0.02	0.01	blup	53	0.00	9.5e-02	6.48	8.8	1.7e-18	0.07	0.09	0.05	TRUE
78	The Cancer Genome Atlas	Prostate Adenocarcinoma	MOV10	0.03	0.00	lasso	9	0.00	9.9e-02	14.57	8.9	3.9e-19	0.47	0.01	0.80	FALSE
79	The Cancer Genome Atlas	Prostate Adenocarcinoma	OLFML3	0.04	0.00	blup	45	0.02	4.3e-03	-6.16	-5.4	7.4e-08	0.02	0.00	0.71	FALSE
80	The Cancer Genome Atlas	Prostate Adenocarcinoma	ST7L	0.31	0.43	enet	12	0.42	3.4e-47	8.07	10.1	5.4e-24	0.44	1.00	0.00	FALSE
81	The Cancer Genome Atlas	Soft Tissue Sarcoma	ST7L	0.11	0.13	lasso	7	0.12	1.5e-07	8.07	10.7	7.8e-27	0.51	0.94	0.05	FALSE
82	The Cancer Genome Atlas	Skin Cutaneous Melanoma	ST7L	0.29	0.29	enet	5	0.26	1.6e-07	8.11	8.6	7.9e-18	0.35	0.66	0.04	FALSE
83	The Cancer Genome Atlas	Stomach Adenocarcinoma	ST7L	0.23	0.23	lasso	4	0.23	1.3e-16	8.07	9.5	1.6e-21	0.44	1.00	0.00	FALSE
84	The Cancer Genome Atlas	Thyroid Carcinoma	MOV10	0.06	0.06	lasso	7	0.05	9.4e-06	14.22	15.0	1.0e-50	0.83	0.01	0.99	FALSE
85	The Cancer Genome Atlas	Thyroid Carcinoma	ST7L	0.51	0.62	lasso	3	0.62	1.1e-75	8.07	8.1	4.8e-16	0.38	1.00	0.00	FALSE