Best TWAS P=9.65e-09 · Best GWAS P=3.29e-28 conditioned to 8.46e-28
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | TPD52 | 0.31 | 0.03 | lasso | 6 | 0.15 | 5.6e-06 | 5.6 | 5.7 | 1.5e-08 | 0.59 | 0.22 | 0.57 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HEY1 | 0.22 | 0.00 | enet | 2 | 0.00 | 3.6e-01 | 5.8 | -5.7 | 1.1e-08 | -0.77 | 0.06 | 0.13 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MRPS28 | 0.07 | 0.04 | enet | 19 | 0.03 | 1.1e-03 | 5.8 | -5.7 | 9.7e-09 | -0.80 | 0.04 | 0.94 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZNF704 | 0.04 | 0.01 | blup | 96 | 0.01 | 1.5e-02 | -5.2 | -5.3 | 1.2e-07 | 0.03 | 0.07 | 0.04 | TRUE |