Hub : Genes

TPD52

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0350	0.0150	2.7e-03	0.031	0.021	0.033	0.020	0.037	1.1e-04	1.3e-03	5.8e-05	1.4e-03	2.4e-05
2	GTEx	Adrenal Gland	0.3126	0.0861	9.9e-06	0.032	NA	0.116	NA	0.148	2.6e-02	NA	6.1e-05	NA	5.6e-06
3	GTEx	Artery Tibial	0.3128	0.0626	1.6e-08	0.204	NA	0.177	NA	0.210	7.2e-16	NA	7.8e-14	NA	2.3e-16
4	GTEx	Lung	0.1499	0.0538	4.0e-04	0.031	NA	0.017	NA	0.035	1.9e-03	NA	1.8e-02	NA	9.8e-04
5	GTEx	Muscle Skeletal	0.3109	0.0542	1.7e-11	0.169	NA	0.175	NA	0.184	2.8e-16	NA	6.3e-17	NA	8.5e-18
6	GTEx	Nerve Tibial	0.1068	0.0349	6.1e-05	0.095	NA	0.097	NA	0.090	2.9e-07	NA	2.3e-07	NA	6.3e-07
7	GTEx	Pancreas	0.1820	0.0640	1.2e-03	0.009	NA	0.022	NA	0.040	1.3e-01	NA	3.8e-02	NA	8.4e-03
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1870	0.0530	1.5e-05	0.044	NA	0.135	NA	0.106	1.9e-03	NA	8.0e-08	NA	2.0e-06
9	GTEx	Skin Sun Exposed Lower leg	0.2130	0.0460	7.0e-12	0.127	NA	0.189	NA	0.181	1.2e-10	NA	1.6e-15	NA	6.5e-15
10	NTR	Blood	0.0385	0.0121	3.2e-06	0.022	0.024	0.023	0.027	0.023	7.0e-08	2.0e-08	6.2e-08	3.0e-09	5.2e-08
11	ROSMAP	Brain Pre-frontal Cortex	0.0646	0.0223	1.3e-04	0.022	0.030	0.035	0.030	0.025	5.9e-04	8.4e-05	2.0e-05	7.8e-05	2.9e-04
12	YFS	Blood	0.1129	0.0250	0.0e+00	0.093	0.085	0.092	0.102	0.094	6.5e-29	2.8e-26	1.9e-28	2.0e-31	5.8e-29
13	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0840	0.0370	6.2e-05	0.067	0.098	0.077	NA	0.077	1.1e-04	3.0e-06	3.5e-05	NA	3.4e-05
14	TCGA	Thyroid Carcinoma	0.1160	0.0470	6.4e-05	0.013	0.023	0.026	NA	0.022	1.7e-02	2.5e-03	1.2e-03	NA	2.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.3	0.5	2.2	-0.4	1.5	0.7	-0.1	0.3	-0.3	0.7	0.6	0.6	1.1	0.1	0.8	0.4	0.8
Bipolar Disorder or Schizophrenia	0.3	0.8	3.9	0.2	0.3	1.4	-0.3	-0.3	-1.2	1.1	-0.2	0.0	0.8	1.1	2.0	-0.0	0.4
Depressed Affect (Nagel 2018)	0.9	1.9	3.6	-1.3	-0.6	0.0	1.8	1.7	1.3	0.2	0.9	1.8	-1.8	-0.3	-1.6	1.9	1.9
Depression (Nagel 2018)	3.1	4.6	9.2	-1.7	-1.1	1.4	2.4	1.9	2.4	1.1	1.6	2.4	-3.0	-0.6	-3.0	3.0	2.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.7	-0.1	1.3	1.2	0.9	-0.3	0.3	0.9	0.8	1.2	0.3	-0.2	-0.0	0.4	0.9
Neuroticism (Nagel 2018)	0.8	1.9	6.6	-0.9	-0.1	0.4	1.9	2.1	0.7	0.7	1.0	1.3	-1.7	0.3	-1.3	1.8	2.6
Schizophrenia (2018)	0.4	0.8	3.5	0.6	-0.9	1.2	-0.3	-0.6	-1.2	0.8	-0.7	-0.5	0.1	1.3	1.9	-0.4	-0.4
Schizophrenia vs Biploar Disorder	1.0	1.3	3.7	-0.5	-1.9	-1.9	0.7	-0.0	0.7	-1.9	-0.8	-0.4	-0.0	-1.8	-0.7	0.2	-1.1
Worry (Nagel 2018)	0.3	0.7	5.7	-0.6	0.6	-0.1	1.4	0.7	0.0	-0.2	0.4	0.4	-0.4	-0.0	-0.2	0.9	2.4
Alzheimer’s Disease (in mother)	1.0	1.2	3.3	-1.8	0.5	-1.2	0.7	-0.7	1.4	-1.0	0.6	1.8	0.1	-1.4	-1.1	0.9	0.5
Alzheimer’s Disease (in father)	1.1	1.2	5.8	-0.4	0.6	2.4	2.0	0.2	-0.2	2.0	0.7	0.4	-0.4	0.5	-0.2	0.5	0.9
Alzheimer’s Disease (including proxy)	0.7	1.1	3.5	-1.0	0.4	1.2	1.9	0.0	0.6	1.0	1.6	1.7	-0.2	-0.1	-0.7	0.8	0.8
Crohns Disease (2017)	1.1	2.4	7.0	1.8	-0.9	0.3	-2.3	0.3	-2.4	0.7	-1.3	-1.5	0.6	1.2	1.8	-1.5	-2.6
Irritable Bowel Disease (IBD)	0.9	2.2	6.3	1.4	-0.0	2.0	-2.0	1.4	-2.0	2.5	-0.2	-0.6	-1.0	1.7	0.9	-0.6	-2.0
Ulcerative Colitis (UC)	1.2	2.2	9.2	1.1	0.4	2.7	-1.4	1.7	-1.4	3.0	0.6	0.1	-1.5	1.6	0.1	0.1	-1.0
Major Depression (MDD)	1.4	1.8	4.8	1.6	-1.5	2.0	-1.2	1.0	-0.8	2.2	1.0	0.4	-1.6	0.9	-0.3	-0.3	1.7
Reaction Time	0.7	1.3	3.5	1.1	-1.0	-0.6	-0.9	-0.5	-1.0	-1.3	-1.9	-1.7	1.6	0.7	0.9	-1.2	-0.4
Verbal and Numeric Reasoning (VNR)	0.7	1.8	4.3	-0.7	1.6	2.1	1.2	0.7	1.3	1.9	1.9	1.8	-0.5	-0.0	-1.0	1.2	0.5
Breast Cancer	0.6	1.4	4.8	-1.2	-0.1	0.8	2.2	1.3	0.8	1.4	1.0	1.0	-1.7	0.4	-1.0	1.4	0.9
Ovarian Cancer	0.3	0.4	2.6	-0.5	-0.4	0.4	-1.6	0.4	0.3	0.3	-0.8	-0.6	-0.4	0.4	-0.6	-0.2	-0.5
Prostate Cancer	1.3	1.8	6.8	-0.5	0.5	2.1	1.2	1.3	0.0	2.6	1.1	0.8	-1.8	1.3	0.0	0.9	1.7
Age at First Birth	1.7	2.5	7.2	-1.2	2.7	2.4	1.4	-1.9	0.9	2.0	1.9	2.2	0.7	-0.7	0.0	1.0	0.3
Bipolar Disorder (2011)	2.4	2.3	6.2	0.9	1.0	-0.2	-1.7	-2.1	-1.7	-0.3	-1.7	-0.7	2.3	0.7	2.5	-1.6	-1.5
Body Mass Index (BMI) (2010)	0.6	0.9	3.1	1.0	0.1	0.5	-1.8	-1.0	-0.9	0.3	-0.2	-1.3	1.2	-0.1	1.3	-0.7	-0.8
Coronary Artery Disease (CAD)	1.2	1.5	3.8	-1.4	1.2	1.3	0.4	0.9	1.0	1.3	1.9	1.3	-1.0	-0.6	-1.3	1.6	1.0
Crohns Disease (2012)	0.7	1.1	3.2	1.2	-0.4	0.8	-1.8	0.9	-1.6	1.1	-0.5	-0.8	0.0	1.0	0.9	-1.0	-1.1
Mean Putamen Volume	2.3	2.6	6.4	1.9	-1.4	-1.7	-0.9	-0.6	-1.9	-1.5	-2.5	-1.8	0.9	1.5	1.0	-1.8	-2.1
Fasting Glucose	7.4	8.9	17.5	3.7	-1.4	0.2	-2.1	-1.5	-4.2	0.3	-3.1	-3.7	2.6	3.4	4.1	-3.8	-3.4
HbA1C	0.5	0.5	1.7	0.4	0.2	0.0	0.5	-0.4	-0.4	-0.8	-0.7	-0.5	1.3	0.6	1.0	-0.8	-1.1
HDL Cholesterol	0.3	0.5	1.9	0.6	0.4	0.8	-1.4	1.0	-0.4	0.6	-0.4	-0.6	-0.2	0.7	-0.1	-1.0	0.2
LDL Cholesterol	0.4	0.6	1.9	0.1	-1.4	-0.8	-0.2	0.9	0.1	-0.7	-0.3	1.1	-0.2	1.3	-0.2	0.1	-1.3
Lupus	0.6	0.9	2.5	1.2	1.3	0.6	-0.9	-0.2	-0.7	0.5	0.0	-0.2	0.8	1.3	1.2	-0.8	-1.6
Neuroticism (2016)	3.5	5.0	16.6	-1.7	-1.2	0.4	1.9	2.2	2.5	1.5	2.1	2.2	-4.1	-0.1	-2.8	2.9	2.8
Primary Biliary Cirrhosis	0.3	0.4	1.0	0.3	0.8	1.0	-0.8	0.1	-0.6	0.2	-0.8	-0.6	0.2	0.3	1.0	-0.8	0.3
Rheumatoid Arthritis	2.1	2.9	17.8	-0.6	-0.2	-4.1	-0.5	0.2	0.4	-4.2	-0.9	0.2	1.8	-0.7	-0.0	-0.5	0.8
Schizophrenia (2014)	0.4	0.9	3.1	0.6	-0.8	0.0	-0.7	-0.7	-1.3	-0.5	-1.6	-1.1	1.3	0.1	1.8	-0.9	-0.3
Triglycerides	0.4	0.7	1.7	-0.2	-0.7	-1.1	1.0	0.5	0.6	-1.3	0.5	1.1	-0.2	-1.0	-0.9	0.2	0.8
Type 2 Diabetes (T2D) (2012)	1.1	1.3	3.5	0.6	0.3	0.1	-0.2	-1.6	-1.2	-0.7	-1.1	-1.8	1.6	1.0	1.9	-1.0	-0.1
Ulcerative Colitis	0.6	0.9	3.5	0.8	0.5	1.4	-1.3	1.4	-0.8	1.9	-0.0	-0.6	-0.7	0.8	-0.2	-0.7	-0.2
Blood Eosinophil Count	1.9	14.7	31.0	-4.7	-2.0	-4.3	0.4	-0.5	5.6	-4.1	2.7	3.4	-2.4	-5.0	-5.1	4.6	4.0
Blood Platelet Count	0.0	0.6	1.8	-0.1	-1.1	0.3	1.0	1.3	0.2	-0.5	0.6	1.1	-0.8	-0.1	-0.1	0.3	1.4
Blood Red Count	0.2	2.2	13.3	-0.4	-0.2	-3.6	-2.4	0.0	0.0	-2.8	-1.0	1.0	0.8	-0.9	-0.3	-0.5	0.1
Blood White Count	0.1	0.8	1.9	-1.3	0.2	0.1	0.5	1.1	0.9	-0.3	0.8	1.1	-0.4	-0.7	-1.4	1.0	1.1
Heel T-Score	0.6	4.9	32.0	-1.4	5.7	0.9	0.3	-2.1	1.9	0.0	1.4	0.6	3.2	-2.2	0.4	0.5	-2.7
BMI	0.5	2.8	11.6	1.9	-1.9	-1.1	-3.4	-0.8	-1.3	-1.1	-2.2	-1.9	0.7	1.8	0.3	-1.7	-0.6
Height	0.1	2.7	8.0	1.8	-1.8	1.5	0.2	0.8	-2.4	2.0	-0.6	-1.8	0.3	2.8	1.5	-2.0	-0.9
Waist Hip Ratio (WHR)	0.9	4.0	8.4	-1.8	-1.0	0.0	2.2	2.5	2.4	-0.7	2.5	1.5	-2.3	-0.1	-2.6	2.9	2.4
Systolic Blood Pressure	0.2	0.9	2.7	-1.1	0.4	-1.0	1.6	1.1	1.5	-1.0	0.1	0.6	-0.0	0.4	0.4	1.3	-0.5
Smoking Status	1.0	2.4	7.0	1.7	-1.4	-1.3	-0.8	1.4	-1.6	-1.4	-2.4	-2.6	0.7	0.3	1.1	-2.0	-1.1
Allergy or Eczema	0.9	2.3	8.9	-1.7	2.8	0.2	1.8	-0.5	1.2	-0.6	0.9	1.5	0.7	-3.0	0.4	1.2	1.4
Cardiovascular Disease	0.5	1.7	5.0	-1.1	0.3	-1.6	1.8	2.2	1.8	-1.2	-0.2	0.9	-1.6	0.1	-0.6	1.1	1.3
Hypothyroidism (self reported)	0.4	1.0	2.4	-1.5	-0.1	-1.0	0.1	0.7	1.5	-1.4	0.6	0.3	-0.5	-1.1	-1.3	1.5	0.6
Respiratory disease	2.2	4.9	18.0	-2.5	0.3	-3.3	0.9	-2.5	2.2	-4.2	0.1	1.4	1.7	-3.4	-0.4	1.3	1.9
Type 2 Diabetes (T2D) (2018)	1.1	2.0	5.5	-1.3	0.2	-1.1	1.1	0.8	1.9	-0.6	1.3	0.7	-1.6	-1.2	-2.0	1.9	2.3
Lung FEV1/FVC ratio	0.1	0.7	2.4	0.2	-0.2	-0.5	0.5	1.3	-0.7	-0.1	-0.2	-1.5	-0.1	1.4	-0.5	-0.4	1.3
Lung FVC	0.2	1.2	8.9	-0.7	3.0	0.8	0.7	1.3	0.0	1.6	0.1	0.2	0.6	-0.6	-0.3	0.4	-0.4
Neuroticism	1.3	3.1	8.5	-1.5	-0.7	-0.3	2.9	1.8	1.9	-0.2	1.1	1.0	-2.5	-0.6	-2.0	2.2	2.9
Chronotype (morning person)	1.2	2.7	10.1	-1.0	0.1	3.2	0.2	0.5	0.5	3.2	1.8	2.0	-1.7	0.2	-1.1	1.1	1.9
Hair Pigment	0.0	0.8	3.8	0.6	0.3	1.2	1.1	-0.3	-0.5	1.6	-0.2	-0.3	0.9	0.4	0.5	-0.6	-2.0
Tanning	0.3	3.5	10.8	2.3	-2.5	0.7	-1.9	-0.0	-2.8	1.0	-1.7	-3.3	-0.1	1.4	2.2	-2.0	-0.4
Hand grip strength (left)	1.5	4.0	7.9	-1.6	2.3	2.0	1.2	2.6	1.2	2.8	2.6	1.2	-2.4	0.5	-2.5	1.0	2.4
Number of treatments/medications taken	1.2	2.1	5.9	2.0	-2.4	-1.0	-1.0	0.1	-0.8	-1.9	-1.9	-1.9	0.8	1.3	1.2	-1.4	-0.7
Average weekly spirits intake	2.0	2.4	5.0	1.7	-0.8	-1.8	0.1	-0.0	-1.6	-1.8	-1.7	-1.8	2.2	0.3	1.9	-1.9	-1.8
Sensitivity / hurt feelings	0.8	1.4	5.0	-1.3	-0.4	-0.1	0.3	0.7	1.3	0.4	1.1	0.7	-1.1	-0.8	-2.0	1.9	2.2
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.1	-0.6	-0.9	1.8	0.7	1.9	1.4	1.3	0.8	1.8	-1.6	0.6	-1.7	2.0	0.9
Hearing difficulty/problems: Yes	0.6	0.8	2.2	-1.2	0.7	-0.7	1.4	0.7	1.0	-1.2	0.7	0.6	0.8	-1.5	0.2	0.7	-0.5
Relative age of first facial hair	0.9	1.9	7.6	0.5	1.0	2.5	1.5	0.2	-0.8	2.8	-0.5	-0.0	-0.4	2.2	1.5	0.2	-1.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	5.3	0.5	-2.3	1.0	0.1	1.0	0.4	-0.0	0.5	0.2	-1.4	0.5	-0.6	0.8	0.3
Ever used hormone-replacement therapy (HRT)	2.1	2.7	10.4	1.0	-0.0	-1.1	0.5	-0.1	-1.9	-1.1	-1.9	-1.0	2.8	0.7	1.9	-1.8	-3.2
Ever had hysterectomy (womb removed)	5.0	5.6	13.7	1.8	-1.4	-3.6	-0.8	-0.2	-2.0	-3.6	-3.7	-2.9	2.8	0.1	1.4	-3.0	-1.6
Systolic blood pressure, automated reading	0.2	0.6	2.7	0.5	-0.2	-0.7	-0.4	-0.1	-0.4	-0.7	-0.6	0.1	1.6	1.1	1.3	-0.7	-0.7
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	5.9	-1.3	0.7	-0.4	1.0	-0.3	0.7	0.2	0.3	0.5	-1.7	-1.8	-0.8	0.7	2.4
Angina	0.4	0.5	1.5	-0.6	-0.1	-0.6	0.7	0.5	0.9	-0.8	0.1	-0.6	-0.9	-1.1	-0.2	0.8	-1.2
Medication for hormone replacement therapy	1.6	1.8	4.4	1.5	-1.0	0.6	-2.1	-1.9	-1.7	0.4	-0.6	-1.1	0.9	0.7	1.4	-1.9	-1.4
Vitamin and mineral supplements	0.8	1.0	3.1	-1.8	0.4	-1.6	0.6	0.6	1.1	-0.9	0.5	-0.1	-0.2	-0.6	-1.6	1.2	1.0
Supplements: Zinc	1.4	1.6	3.8	-1.6	0.5	-0.8	0.3	0.0	1.7	-0.7	1.1	1.9	-1.5	-1.9	-1.4	1.3	0.8
Medication: Co-codamol	1.3	1.5	4.6	1.1	-1.2	-0.6	-2.2	-0.2	-1.1	-1.0	-1.9	-1.3	1.3	0.7	0.7	-1.2	-1.0
Medication: Metformin	0.1	0.1	0.4	0.5	-0.5	0.1	0.1	0.7	0.0	0.6	-0.4	-0.3	0.3	0.0	0.1	0.3	0.6
Diabetes (father)	1.1	1.4	5.3	-0.8	0.1	-0.2	0.7	-1.1	1.4	-0.2	1.6	1.1	-1.4	-0.8	-1.1	1.4	2.3
Diabetes (mother)	0.2	0.3	2.0	0.5	-1.4	0.3	0.4	0.0	0.3	0.6	0.1	0.6	-0.4	0.2	-0.1	0.2	0.2
Severe depression (siblings)	2.8	3.2	8.1	2.8	-0.4	1.2	-1.6	-0.1	-2.1	1.7	-1.5	-2.3	1.1	2.3	2.0	-2.0	-1.7
Pack years adult smoking proportion	0.4	0.6	1.3	1.2	-0.2	-0.5	0.8	0.6	-0.5	-1.1	-0.8	-0.5	0.8	0.1	1.1	-0.9	-0.9
Impedance of leg (right)	0.4	2.0	4.5	-1.7	1.5	0.6	1.8	1.5	1.0	0.8	1.3	2.1	-0.3	-1.0	-1.2	1.9	1.7
Leg fat-free mass (left)	0.4	2.1	4.1	1.8	-2.0	1.2	-1.9	-1.4	-1.4	1.0	-0.5	-1.6	-0.0	2.0	1.2	-1.3	-1.6
Trunk fat percentage	1.1	4.5	9.8	2.4	-3.1	-1.1	-2.1	0.2	-2.3	-1.5	-2.8	-2.7	1.4	2.6	1.6	-2.1	-2.0
Hand grip strength (right)	1.7	4.7	10.0	-1.7	2.9	2.5	1.1	2.4	1.6	3.2	3.1	1.9	-2.4	0.1	-2.7	1.4	0.6
Townsend deprivation index at recruitment	3.1	4.3	12.6	2.1	-1.2	-2.4	-3.0	-1.1	-2.0	-1.8	-3.5	-2.0	1.5	0.8	1.6	-2.3	-2.1
Current tobacco smoking	0.6	1.0	2.0	1.3	0.1	-0.9	-0.2	1.0	-1.1	-1.1	-1.4	-1.0	1.1	0.5	1.3	-1.4	0.0
Average weekly fortified wine intake	1.5	1.7	6.1	-1.2	0.0	-0.5	0.8	0.4	1.4	-0.2	1.1	1.2	-2.2	-0.3	-2.1	1.2	2.5
Maternal smoking around birth	0.7	1.0	7.1	-0.3	-2.7	-1.0	0.2	-0.7	-0.2	-1.3	-0.1	0.4	-0.7	-1.0	-0.8	0.6	-0.9
Fed-up feelings	0.7	1.3	3.4	-0.9	-0.5	0.7	1.4	1.6	0.7	0.8	0.7	1.4	-1.2	-0.5	-1.1	1.8	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.5	3.4	9.5	-1.5	-1.4	1.3	1.8	0.9	2.1	1.1	1.5	2.1	-2.4	-0.5	-2.9	3.1	1.0
Relative age voice broke	0.4	0.7	2.5	0.2	0.5	0.9	0.4	0.9	-0.6	1.6	-1.1	0.2	-1.6	0.8	0.0	-0.3	0.0
Taking other prescription medications	0.5	0.8	2.8	-0.1	-1.5	-0.6	0.3	1.4	0.9	-1.7	-0.3	-0.7	-1.0	-0.9	-0.7	0.5	0.2
Age when periods started (menarche)	1.7	4.1	10.0	-2.1	0.8	-1.5	3.1	1.9	3.0	-1.4	0.7	0.9	-1.8	-2.1	-3.2	2.3	1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	3.1	1.1	-0.4	-1.3	-0.6	-0.0	-1.2	-1.5	-1.5	-0.8	1.7	0.5	1.3	-0.9	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.3	0.2	0.3	-0.8	-1.2	-1.5	0.8	-0.4	0.1	-0.5	0.9	-0.9	-0.2	-0.4	-1.3
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	5.5	-2.0	2.3	0.3	1.4	0.9	1.9	-0.0	2.2	1.9	-1.0	-1.6	-0.9	2.2	-0.1
Qualifications: CSEs or equivalent	3.0	3.9	8.1	-2.5	0.1	-0.3	2.4	1.5	2.1	-0.0	2.1	2.2	-2.4	-1.4	-2.1	2.9	2.6
Serious illness, injury or assault to yourself	2.9	3.5	8.2	-1.9	1.3	0.9	0.7	1.9	1.8	1.3	1.9	2.9	-2.1	-2.0	-2.1	1.9	2.4
High blood pressure	0.2	0.7	2.2	-0.6	-0.3	-1.1	1.5	1.1	1.0	-1.1	-0.5	0.3	-0.6	0.7	0.1	0.7	0.3
Hayfever, allergic rhinitis or eczema	0.8	1.8	10.1	-1.2	3.2	0.3	1.4	-0.8	0.8	-0.4	0.7	0.9	0.7	-2.4	0.5	0.7	1.3
Multivitamins +/- minerals	0.9	1.2	2.9	1.6	-0.3	1.7	-1.1	-0.4	-1.6	1.6	-0.2	0.9	-0.4	0.8	1.2	-1.2	-0.4
Stomach or abdominal pain in last month	0.4	0.5	1.9	0.0	0.4	0.9	1.3	0.4	0.7	0.3	0.8	0.5	-0.6	-1.4	0.7	0.5	0.5
Supplements: Glucosamine	3.3	4.2	7.1	2.3	-2.6	-1.2	-1.7	-1.6	-2.3	-1.9	-2.5	-1.6	1.6	1.6	2.7	-2.6	-1.9
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	0.3	-1.1	-0.1	-0.8	-0.9	0.3	-0.3	-0.0	0.8	0.6	-0.1	0.6	-0.1	-1.0
Medication: Atenolol	0.9	1.1	3.0	-1.5	-0.7	-0.8	0.8	-1.1	1.7	-1.1	0.3	0.1	-1.4	-0.6	-1.0	1.6	-0.4
Medication: Levothyroxine sodium	0.4	0.7	2.4	-0.5	0.1	0.3	-0.7	1.6	1.0	-0.3	0.8	-0.0	-0.2	-1.2	-1.0	1.0	0.7
Sitting height	0.2	1.5	7.3	0.7	-0.5	2.5	-0.4	0.4	-1.0	2.7	1.3	-0.7	-0.7	1.5	0.4	-0.4	0.4
Chronic bronchitis/emphysema (father)	0.4	0.4	1.8	-0.4	-1.1	-1.3	0.3	0.2	-0.1	-1.4	-0.6	-0.3	0.6	-0.3	-0.2	0.1	0.1
High blood pressure (mother)	0.5	0.7	2.5	1.0	0.6	0.1	-1.1	-1.2	-0.1	0.2	-0.5	-0.1	1.3	0.5	1.0	-0.9	-1.6
Body mass index (BMI)	0.6	2.4	6.3	1.9	-2.5	-0.4	-2.4	-0.4	-1.2	-0.8	-1.7	-1.6	0.6	2.0	0.9	-1.4	-1.5
Impedance of leg (left)	0.5	2.5	5.8	-2.0	1.4	0.3	2.4	2.0	1.3	0.4	1.4	2.1	-0.6	-1.1	-1.5	2.1	1.8
Leg predicted mass (left)	0.4	2.2	4.5	1.9	-2.0	1.2	-2.0	-1.3	-1.4	1.0	-0.5	-1.6	0.0	2.1	1.3	-1.3	-1.6
Trunk fat mass	0.9	3.7	8.9	2.3	-3.0	-0.4	-2.2	0.2	-2.1	-0.7	-2.1	-2.4	0.9	2.8	1.4	-1.9	-1.8
Waist circumference	0.4	1.5	9.7	1.0	-3.1	-0.4	-1.4	0.9	-0.4	-0.7	-0.6	-1.2	-0.4	2.0	-0.3	-0.1	-0.5
Number of incorrect matches in round	0.6	0.9	3.4	-0.0	-1.8	-1.1	-1.6	0.7	-0.4	-1.5	-0.2	-0.6	0.4	-1.5	-0.4	0.3	-0.7
Past tobacco smoking	1.3	2.4	6.5	-1.8	2.0	1.2	0.9	-0.2	1.5	0.9	2.2	2.5	0.1	-0.7	-1.3	1.6	2.4
Alcohol usually taken with meals	2.0	3.2	6.8	-1.3	1.7	1.7	1.4	0.8	2.2	1.1	2.4	2.6	-0.9	-1.8	-1.9	1.6	2.4
Nervous feelings	0.3	0.6	3.1	-0.8	0.8	-0.2	1.4	0.1	0.6	0.2	0.5	0.6	-0.2	-0.2	-0.5	0.8	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.3	3.5	-0.7	-1.3	1.7	1.2	1.0	0.8	1.2	0.6	0.9	-1.1	-0.2	-1.6	1.9	0.9
Hearing difficulty/problems with background noise	0.8	1.3	5.8	0.0	-0.5	-2.4	0.8	0.1	0.3	-2.3	-1.5	-1.6	0.7	-0.7	0.5	-0.1	-0.6
Hair/balding pattern: Pattern 2	0.1	0.1	0.7	0.3	0.1	0.4	0.4	-0.4	-0.3	0.4	-0.1	0.1	0.1	-0.2	0.8	-0.2	0.1
Had menopause	0.8	1.0	2.9	0.6	-1.7	-0.8	1.5	-0.1	-1.3	-0.4	-1.1	-0.8	0.7	0.4	1.3	-1.0	-1.0
Had other major operations	0.4	0.5	2.9	0.3	0.3	1.7	-0.4	0.4	-0.6	1.2	0.5	-0.5	-0.2	-0.3	1.0	-0.1	-0.0
Forced vital capacity (FVC)	0.5	1.8	3.5	-1.8	1.9	1.3	0.9	1.6	1.1	1.7	1.2	0.6	-0.9	-1.1	-1.5	1.4	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	4.8	0.7	0.4	-1.0	-1.6	-2.2	0.2	-0.6	-0.5	-1.1	1.5	-0.4	0.3	-0.7	-1.9
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	6.0	-0.0	-1.1	1.3	1.1	1.3	1.0	1.4	0.6	0.7	-2.5	0.5	-1.3	1.5	-0.5
Qualifications: None of the above	2.9	6.3	13.5	1.6	-2.0	-3.7	-2.2	-2.3	-1.4	-3.7	-3.0	-2.9	3.5	0.2	1.3	-2.1	-2.6
Financial difficulties in last 2 years	0.8	1.1	3.1	1.0	-1.4	-0.1	-0.7	-1.1	-1.4	-0.3	-0.9	-1.8	0.8	0.4	1.4	-0.7	-1.3
Mouth/teeth dental problems	0.8	1.3	4.0	-1.1	1.2	1.6	0.7	-0.5	0.8	1.6	1.4	2.0	-0.5	0.3	-0.6	1.0	1.2
Heart attack	0.6	0.7	3.5	-1.4	0.8	-0.8	0.1	-0.1	1.1	-0.4	0.5	-0.1	-0.4	-1.9	-0.8	0.8	0.2
Allergy	1.3	2.9	8.1	2.2	-2.8	1.2	-2.1	0.0	-1.9	1.9	-0.6	-1.0	-0.8	2.8	0.2	-1.2	-1.7
Pain all over the body in last month	0.4	0.5	2.5	-0.4	0.7	0.5	-0.1	0.9	0.0	0.7	0.1	-0.0	-0.6	0.7	-0.8	0.0	1.6
Diabetes (self-reported)	1.0	1.5	3.4	-0.9	-0.5	-0.3	0.7	0.8	1.8	0.1	1.1	1.2	-1.8	-0.9	-1.8	1.7	1.7
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.7	-0.5	0.5	-0.0	0.6	0.1	0.1	-0.3	-0.6	0.1	0.6	-0.3	0.8	-0.1	0.3
Medication: Ramipril	0.9	1.2	3.5	-1.9	1.0	-0.6	0.2	0.3	1.6	-0.4	0.4	0.4	-0.9	-1.5	-1.4	1.1	1.5
Medication: Simvastatin	1.1	1.5	6.4	1.7	-0.6	-0.7	-0.8	1.3	-1.5	0.3	-1.5	-2.5	-0.5	1.4	0.8	-1.1	-0.7
Fluid intelligence score	0.5	1.1	2.5	-0.9	1.3	1.6	1.2	0.7	1.0	1.5	1.4	1.0	-0.1	-0.8	-0.8	0.9	-0.1
Illnesses of siblings	1.3	1.9	4.7	-1.0	0.4	1.4	1.8	1.4	1.3	1.7	1.9	0.8	-2.2	-0.3	-1.6	1.3	0.7
Neuroticism score	1.4	3.0	8.1	-1.5	0.1	0.6	2.9	1.5	1.9	0.8	1.5	1.5	-2.1	-0.3	-1.8	2.7	2.2
Weight	0.5	2.6	7.8	2.1	-2.8	0.6	-2.1	-0.2	-1.5	0.3	-1.0	-1.9	0.2	2.7	1.1	-1.4	-1.4
Impedance of arm (right)	0.2	0.7	2.9	-0.4	0.0	-1.1	1.7	1.2	-0.2	-1.2	-0.5	-0.0	-0.2	-0.3	-0.4	0.4	1.3
Arm fat percentage (right)	0.8	3.0	6.6	2.1	-2.6	-0.9	-2.2	-0.1	-1.8	-1.2	-2.3	-2.0	0.8	2.3	1.2	-1.6	-1.4
Trunk fat-free mass	0.2	1.2	4.5	0.9	-0.8	2.1	-1.3	-0.6	-0.5	2.0	1.1	-0.4	-0.5	1.6	0.4	-0.4	-0.4
Hip circumference	0.6	2.4	8.7	1.8	-3.0	0.2	-2.4	-0.3	-1.7	0.2	-1.3	-1.6	0.2	2.3	0.9	-1.4	-1.1
Time employed in main current job	0.3	0.3	2.4	-0.3	0.4	0.2	0.4	0.9	-0.1	0.4	0.5	1.6	-0.5	0.3	0.3	0.2	0.4
Alcohol intake versus 10 years previously	0.2	0.4	1.7	1.0	-1.3	0.1	0.4	0.3	0.4	-0.1	-0.8	-0.2	-0.9	0.3	-0.0	0.1	-0.5
Father’s age at death	0.7	0.9	3.8	-0.7	-0.8	0.7	-0.0	0.1	0.4	0.7	0.3	1.9	-2.0	-0.0	-1.1	1.0	1.0
Worrier / anxious feelings	1.6	3.1	11.3	-1.5	0.3	-0.3	2.2	2.6	1.7	-0.9	1.4	1.6	-1.1	-0.7	-1.8	2.0	3.4
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	3.9	-0.3	-0.6	1.3	0.9	1.1	1.1	1.4	0.9	1.1	-1.7	0.2	-1.3	2.0	0.6
Falls in the last year	0.4	0.6	2.5	-0.3	-0.1	1.6	0.3	0.3	1.1	1.1	0.7	0.7	-0.2	-0.8	-0.7	0.6	0.1
Hair/balding pattern: Pattern 3	0.2	0.3	1.1	-0.8	-0.4	-1.0	-0.6	0.2	0.3	-0.9	-0.2	0.0	-0.1	0.8	-0.8	0.4	0.3
Number of live births	0.2	0.3	1.1	-0.0	1.1	-0.2	-0.5	-1.0	-0.0	-0.5	0.2	-0.5	0.6	-0.8	0.4	-0.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	5.9	-1.9	2.4	1.5	1.4	1.8	1.2	1.7	1.4	0.2	-1.2	-1.1	-1.7	1.5	1.7
Pulse rate	0.8	1.4	4.1	-1.3	2.0	1.1	0.4	0.7	1.1	0.8	1.6	1.7	-0.2	-1.3	-0.6	1.5	0.3
Happiness	0.4	0.4	3.2	-0.3	0.4	0.6	1.8	-0.2	0.7	0.5	0.5	0.2	-0.1	-0.1	0.2	1.1	0.0
Noisy workplace	0.4	0.5	1.6	0.1	1.0	0.2	-0.9	-1.3	0.0	-0.4	0.5	0.6	-0.1	-1.1	0.9	-0.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.6	1.4	5.3	-0.5	2.3	1.4	-0.1	-0.4	0.9	1.8	1.5	1.6	-0.8	-0.9	-0.8	0.6	-0.6
Serious illness, injury or assault of a close relative in last 2 years	2.7	3.1	6.4	-1.5	0.7	1.9	1.0	1.5	1.1	2.3	2.5	2.0	-2.4	-1.4	-1.3	2.3	1.2
Mouth/teeth dental problems: Dentures	0.6	1.0	2.6	0.4	-1.3	-1.3	-0.0	0.2	-0.6	-1.6	-1.5	-1.2	0.7	-0.9	0.2	-0.4	-1.6
Asthma	1.6	3.2	8.9	-2.2	1.5	-2.4	0.7	-1.8	2.1	-3.0	0.6	1.4	1.3	-2.4	-0.8	1.1	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.4	1.2	-0.6	-0.3	-0.7	-0.2	-0.6	-0.8	-1.1	-1.0	0.5	0.2	0.6	-0.8	-0.6
Medication: Cholesterol lowering	1.8	2.8	10.5	1.8	-1.4	-2.5	-0.9	-0.2	-0.6	-2.5	-2.3	-3.2	0.7	-0.7	0.5	-2.0	-0.0
Depression (self-reported)	0.5	0.6	2.6	1.3	0.3	1.6	0.5	1.0	-0.6	1.0	-0.1	0.2	-0.5	0.5	0.5	-0.2	-0.6
Medication: Lansoprazole	1.7	1.9	4.3	0.4	0.9	-1.8	-1.8	-1.1	-0.4	-2.1	-1.7	-0.9	1.6	-1.5	1.3	-1.6	-1.2
Prospective memory result	0.3	0.4	1.9	0.9	0.2	0.1	-0.2	1.4	-0.4	0.0	-0.4	0.5	0.1	0.3	0.6	-0.7	-1.0
Lung cancer (father)	0.1	0.2	0.7	0.4	-0.2	0.1	-0.8	-0.6	-0.2	-0.6	-0.6	-0.2	-0.0	-0.1	0.3	-0.4	-0.2
Illnesses of mother	0.4	0.5	3.6	-0.3	0.2	-1.0	0.3	-0.1	0.2	-1.1	-0.1	-0.5	-0.3	-0.2	-0.1	-0.1	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	7.6	-1.2	2.8	2.2	1.3	1.9	0.4	2.5	1.4	-0.0	-1.1	-0.3	-1.1	1.0	1.9
Pulse wave Arterial Stiffness index	1.0	1.2	5.9	-0.9	0.7	0.8	2.0	2.4	0.7	0.4	1.1	1.3	-0.3	-0.2	-0.8	1.1	0.2
Impedance of arm (left)	0.1	0.7	2.5	-0.0	-0.2	-1.2	1.6	0.9	-0.7	-1.4	-1.1	-0.6	0.7	-0.3	0.4	-0.2	0.3
Arm fat mass (right)	0.7	2.9	6.4	2.1	-2.5	-0.3	-2.5	-0.2	-1.8	-0.7	-1.9	-2.0	0.7	2.5	1.2	-1.6	-1.3
Trunk predicted mass	0.2	1.1	4.0	0.9	-0.8	2.0	-1.4	-0.6	-0.5	1.9	1.0	-0.5	-0.5	1.5	0.5	-0.5	-0.4
Standing height	0.1	1.4	5.0	0.7	-0.7	2.2	0.2	0.3	-1.1	2.2	1.1	-0.9	-0.5	1.9	0.6	-0.6	0.3
Length of working week for main job	0.3	0.4	2.9	0.7	-0.1	0.4	-1.7	0.9	-0.3	0.4	0.1	0.1	-0.4	-0.1	-0.4	-0.4	-0.3
Exposure to tobacco smoke at home	0.5	0.5	2.1	0.9	-0.6	-0.2	-0.6	0.7	-0.2	-0.0	-0.6	-0.9	-1.4	0.6	0.2	-1.0	0.8
Breastfed as a baby	1.0	1.3	4.0	0.8	0.7	0.0	-0.9	-1.6	-1.4	-0.1	-0.8	-1.4	2.0	1.5	1.0	-1.4	-0.1
Tense / ‘highly strung’	0.2	0.4	1.6	-0.3	0.4	0.5	1.3	0.1	-0.3	0.5	0.9	0.1	-0.6	1.0	0.2	0.6	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.0	-0.3	-0.5	0.6	0.0	-0.0	0.7	0.8	0.2	0.7	-0.5	-0.2	-0.6	1.0	1.0
Hair/balding pattern: Pattern 4	0.9	2.3	7.7	2.5	0.7	2.7	-1.2	0.7	-1.9	2.8	-0.2	-0.4	0.1	1.3	0.6	-1.6	-0.1
Birth weight of first child	0.2	0.4	4.3	-0.2	0.3	-0.0	-0.2	-2.1	0.5	0.4	0.3	0.7	0.1	0.2	0.4	0.1	-0.5
Peak expiratory flow (PEF)	0.9	2.1	8.5	-2.3	2.9	0.1	1.8	0.9	1.7	-0.8	1.1	0.1	0.4	-1.5	-1.5	1.6	0.4
Pulse wave reflection index	0.4	0.5	2.5	-0.1	-1.2	0.3	1.1	1.6	0.3	-0.1	0.4	0.6	-1.0	0.5	-0.7	0.3	0.0
Ever highly irritable/argumentative for 2 days	0.7	0.9	7.6	0.2	-1.4	-0.3	0.1	2.8	0.3	0.1	-0.4	-0.2	-1.4	0.3	0.0	0.3	-0.1
Loud music exposure frequency	0.6	0.7	1.9	0.3	-0.1	-1.2	-0.9	-1.3	-0.2	-1.4	-0.5	-1.1	0.7	-0.9	0.8	-0.5	0.5
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	8.5	-0.4	1.8	2.4	1.2	1.1	0.7	2.9	1.2	1.1	-1.4	0.4	-0.4	0.6	0.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.6	1.2	0.8	0.1	-0.5	0.5	-0.9	0.1	0.2	-1.1	0.4	1.3	0.6	-0.9	-0.2
Blood clot in the leg (DVT)	0.5	0.7	3.9	0.4	-0.0	0.8	0.5	2.0	0.7	0.2	0.2	-0.1	-1.1	1.4	-0.8	-0.1	0.3
Medication: Paracetamol	0.5	0.8	3.8	1.2	-1.9	-0.4	0.5	0.9	-0.9	-1.0	-0.3	-0.3	-1.0	1.3	0.6	-0.3	0.2
Headache pain in last month	0.7	1.1	5.0	1.6	-0.3	1.9	-0.1	0.1	-0.7	0.9	-0.0	-0.3	0.6	1.0	1.4	-0.3	-2.2
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	8.4	-1.5	0.8	2.4	0.2	0.2	0.3	2.2	2.3	2.9	-1.2	0.3	-0.9	1.8	0.2
Glaucoma (self-reported)	0.4	0.4	1.4	0.6	0.4	0.8	1.2	0.4	-0.5	1.0	-0.1	-0.7	0.0	0.6	0.5	0.0	-0.9
Gout (self-reported)	2.5	3.5	9.1	2.6	1.3	0.8	-1.2	-1.4	-2.3	1.2	-1.8	-3.0	1.9	1.8	1.7	-2.7	-0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.6	-0.4	-0.2	-0.5	-1.2	1.3	0.9	-0.7	0.3	-0.4	-0.1	-0.9	-0.9	0.7	0.4
Medication: Amlodipine	1.2	1.7	4.4	1.6	-0.7	-0.2	-0.2	-2.1	-1.3	-0.5	-1.7	-1.5	1.0	0.8	2.1	-1.4	-1.1
Medication: Ventolin 100micrograms inhaler	1.6	2.0	6.5	-0.2	0.3	-2.1	-0.9	-2.5	-0.1	-2.4	-1.1	-0.8	2.5	-0.8	1.0	-0.6	-0.9
Birth weight	1.0	2.1	5.1	-2.3	1.9	0.5	0.8	1.4	1.5	1.6	2.0	1.4	-0.4	-1.2	-1.4	1.9	0.3
Chronic bronchitis/emphysema (mother)	0.5	0.5	2.0	0.7	-1.4	0.3	-0.4	-0.1	-1.1	0.1	-0.9	-1.3	0.2	-0.2	0.7	-0.7	-0.6
High blood pressure (siblings)	0.1	0.2	0.9	-0.2	0.4	-0.2	-0.6	0.2	0.3	-0.9	-0.4	-0.2	0.7	-0.4	0.2	0.3	0.3
Forced vital capacity (FVC), Best measure	0.5	1.9	6.0	-1.1	2.4	2.1	1.1	1.8	0.3	2.4	1.3	0.4	-0.7	-0.4	-0.8	0.9	1.3
Body fat percentage	0.9	3.5	7.6	2.2	-2.8	-0.8	-2.0	0.1	-1.9	-1.2	-2.4	-2.2	1.1	2.5	1.4	-1.8	-1.8
Leg fat percentage (right)	0.4	1.3	3.8	1.4	-1.9	-0.1	-1.5	0.3	-0.9	-0.5	-1.3	-0.9	0.6	1.9	0.7	-0.7	-1.1
Arm fat-free mass (right)	0.2	1.2	3.0	0.9	-1.2	1.7	-1.6	-0.6	-0.5	1.7	0.6	-0.6	-0.1	1.5	0.6	-0.6	-1.1
Exposure to tobacco smoke outside home	2.1	2.8	11.4	1.9	-1.3	-0.4	-1.7	-0.6	-1.9	-0.1	-1.5	-2.2	1.3	1.4	1.9	-1.4	-3.4
Comparative body size at age 10	0.2	0.5	2.3	-0.6	1.4	0.0	-1.5	-1.2	-0.3	0.2	0.1	-0.0	0.4	0.0	0.3	-0.1	-0.4
Number of full brothers	2.0	2.5	6.8	2.0	-2.6	-0.6	-1.3	-1.8	-1.3	-0.4	-1.6	-1.7	0.3	1.8	1.8	-1.5	-1.8
Worry too long after embarrassment	0.5	0.8	4.1	0.2	-0.6	-0.5	1.5	1.2	0.0	0.0	-0.3	-0.4	-0.9	1.1	-0.7	0.4	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	6.7	1.2	-0.9	2.6	0.0	0.2	-0.6	2.5	0.5	0.3	-1.4	0.8	0.3	0.3	0.2
Wheeze or whistling in the chest in last year	0.4	0.8	3.1	0.4	-0.7	-1.5	-0.2	-1.0	-0.4	-1.8	-1.0	-0.6	1.0	-0.8	0.7	-0.5	-0.3
Number of children fathered	0.8	0.9	2.8	0.5	-1.3	-1.7	-1.1	0.6	-0.0	-1.6	-0.3	-1.4	-0.1	-0.4	-0.3	-1.1	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.1	0.3	-0.3	-1.4	-1.0	-0.4	-0.9	-0.6	-1.3	-0.8	0.5	-1.2	0.9	-0.9	-0.3
Age at first live birth	2.1	3.7	10.0	-1.0	2.8	3.2	1.0	1.3	0.9	2.7	2.8	2.0	-0.8	-0.1	-1.0	1.5	2.5
Pulse wave peak to peak time	1.2	1.4	5.9	1.0	-1.0	-0.8	-1.9	-2.4	-0.8	-0.5	-1.2	-1.5	0.3	0.3	0.9	-1.2	-0.3
Health satisfaction	0.7	1.0	2.1	-0.8	1.1	-0.7	1.3	1.1	1.4	-0.8	0.2	0.0	-0.6	-0.2	-1.4	1.0	1.3
Shortness of breath walking on level ground	0.5	0.6	2.8	-0.6	1.3	0.1	-0.0	1.7	0.5	-0.0	0.4	1.3	-0.2	-0.5	-0.4	0.6	-0.1
Qualifications: College or University degree	0.7	2.2	9.3	0.0	1.4	2.2	0.6	2.3	0.2	3.0	1.7	1.4	-1.7	0.8	-0.5	0.5	0.2
Eye problems/disorders: None of the above	0.7	0.8	2.8	-1.1	1.6	0.3	0.5	0.3	0.8	0.3	1.3	1.7	0.3	-0.5	-0.4	0.7	0.4
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.9	-1.0	0.5	0.5	0.3	1.0	0.6	0.7	1.0	0.9	-0.6	-1.1	-0.4	1.2	-1.4
Emphysema/chronic bronchitis	1.8	2.0	6.4	-1.5	-0.1	-0.8	1.9	1.2	1.4	-0.3	1.1	1.3	-1.2	-1.1	-1.8	1.6	2.5
Medication for pain relief, constipation, heartburn	0.5	0.9	6.7	-0.6	2.6	0.8	-0.4	-0.6	-0.1	1.8	0.7	0.7	0.6	-0.4	-0.3	-0.2	-0.1
Neck or shoulder pain in last month	0.7	1.0	5.4	-0.5	0.1	0.6	0.5	-1.2	1.1	-0.2	0.6	2.3	-0.0	-1.1	-0.3	1.3	-1.2
Medication: Blood pressure	0.9	1.5	5.2	0.9	-0.5	-1.8	-0.3	-0.7	-0.1	-1.6	-2.3	-2.0	1.2	-0.7	0.7	-1.3	-0.6
Angina (self-reported)	0.5	0.6	1.6	-0.7	-0.2	-0.9	0.7	0.3	1.0	-1.1	0.1	-0.4	-0.8	-1.3	-0.2	0.9	-1.2
Migraine (self-reported)	0.2	0.3	0.7	-0.6	-0.1	0.4	0.5	0.4	0.6	-0.9	0.7	-0.8	-0.6	-0.7	-0.0	0.4	0.2
Medication: Ibuprofen	0.8	0.9	2.9	1.7	0.3	-0.3	-1.3	-0.6	-1.1	-0.5	-1.3	-1.1	0.6	0.6	0.9	-1.4	-0.2
Medication: Allopurinol	1.5	2.0	4.1	1.8	1.7	0.9	-1.4	-1.0	-1.6	0.6	-1.1	-2.0	1.6	1.7	0.9	-1.9	0.8
Medication: Omeprazole	0.3	0.4	1.8	0.3	-1.3	-0.3	-0.6	-1.2	-0.2	-0.9	-0.6	0.1	0.4	0.1	-0.2	-0.0	0.4
Medication: Seretide 50 evohaler	2.0	2.4	6.9	0.7	-2.5	-2.5	-1.8	-1.3	-0.5	-2.6	-1.3	-0.5	1.4	-0.4	0.6	-1.0	-1.5
Mean time to correctly identify matches	1.4	2.6	6.5	1.6	-0.4	-0.5	-1.0	-1.0	-1.9	-1.1	-2.3	-2.2	2.5	0.9	1.8	-1.8	-1.6
Heart disease (mother)	0.9	1.0	3.7	1.0	-1.4	0.3	0.0	-0.0	-1.9	0.6	-1.3	-0.5	0.2	1.3	1.1	-0.3	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	4.3	-1.7	-0.8	-1.8	0.8	0.9	2.1	-1.9	1.0	1.6	-0.5	-1.8	-1.4	1.8	0.0
Whole body fat mass	0.9	3.8	8.4	2.4	-2.9	-0.1	-2.4	-0.2	-2.1	-0.5	-2.1	-2.3	1.0	2.8	1.5	-1.9	-2.0
Leg fat mass (right)	0.7	2.6	7.4	2.1	-2.7	0.0	-2.1	0.0	-1.6	-0.2	-1.7	-1.7	0.6	2.3	1.1	-1.3	-1.7
Arm predicted mass (right)	0.2	1.2	3.5	0.8	-1.0	1.9	-1.5	-0.2	-0.5	1.9	0.9	-0.4	-0.2	1.6	0.4	-0.4	-1.1
Pulse rate, automated reading	0.8	2.5	5.6	-2.2	1.2	0.4	1.1	0.9	1.7	-0.0	1.9	2.2	-1.2	-1.5	-1.3	2.4	2.2
Alcohol intake frequency.	0.3	0.8	3.0	1.7	-0.7	1.3	-0.5	-0.2	-1.2	0.1	-1.1	-0.4	0.7	0.7	0.5	-1.0	0.1
Comparative height size at age 10	0.4	2.1	6.8	0.6	-1.6	-1.1	-1.1	-2.6	-0.9	-1.4	-0.6	-1.5	2.2	0.6	1.8	-1.2	-1.4
Number of full sisters	0.7	0.9	2.3	0.9	0.7	1.0	-0.2	-0.2	-0.9	0.4	-0.9	0.1	1.2	1.5	1.5	-0.9	-1.2
Suffer from ‘nerves’	0.2	0.3	0.9	-0.1	-0.5	-0.6	1.0	-0.0	-0.1	-0.1	-0.4	-0.4	-0.5	0.7	0.2	0.8	0.6
Overall health rating	0.3	0.6	2.3	-0.6	-0.4	0.0	1.2	-0.2	1.1	-0.8	0.0	0.3	-0.9	-0.9	-0.3	1.5	0.7
Chest pain or discomfort	0.9	1.3	4.8	-0.7	-0.4	-1.7	-0.6	-0.1	1.3	-2.2	0.9	0.9	-0.6	-1.7	-1.1	1.0	0.9
Had major operations	0.9	1.1	3.5	0.2	-1.4	-0.7	-0.2	-1.8	-0.5	-1.9	-1.6	-0.5	1.1	-0.4	0.7	-0.8	-0.5
Age at last live birth	1.6	2.4	11.3	-0.6	3.0	3.4	0.7	0.5	0.3	2.4	1.7	1.1	0.1	-0.4	0.2	0.8	1.0
Family relationship satisfaction	0.5	0.6	2.3	-0.0	1.4	1.5	0.7	0.9	0.4	1.5	0.4	-0.0	-0.4	-0.1	-0.1	0.6	-0.1
Leg pain on walking	0.9	1.2	2.5	-1.1	-0.1	-1.5	0.4	0.3	1.3	-1.5	0.3	0.8	-1.2	-1.4	-1.3	0.9	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.9	1.3	-1.4	-0.5	-0.7	-1.2	-1.2	-0.6	-1.4	-0.4	0.3	0.6	0.7	-0.7	-1.2
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.1	-0.3	1.0	0.3	1.1	1.4	0.0	0.1	0.2	-0.1	-0.3	0.3	-0.8	0.1	1.2
Illness, injury, bereavement, stress in last 2 years	1.4	1.8	4.1	0.8	0.1	-1.2	-0.5	-1.2	-0.4	-1.7	-1.6	-1.9	2.0	1.3	1.0	-1.4	-1.7
Medication: Aspirin	0.8	1.1	2.8	-1.2	-0.7	-1.6	0.4	0.4	1.7	-1.2	0.3	-0.7	-0.8	-1.2	-0.8	1.4	0.6
Supplements: Vitamin C	1.2	1.4	3.7	1.2	-0.7	-0.4	-1.0	-1.5	-1.3	-0.3	-1.0	-0.5	1.3	0.4	1.8	-1.3	-1.9
Knee pain experienced in last month	0.8	1.2	8.1	0.9	-2.8	-0.1	1.5	1.2	-0.1	-0.8	-0.5	-0.1	-1.4	0.1	0.1	-0.1	1.1
Hypertension (Self-reported)	0.2	0.6	2.4	-0.2	-0.1	-0.6	1.6	1.3	0.8	-0.3	-0.3	0.4	-0.7	1.2	0.3	0.6	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	3.3	1.0	-0.4	-0.5	-1.5	-0.9	-0.9	-1.3	-0.9	-0.7	1.8	-0.3	1.3	-1.4	-0.8
Illnesses of father: Heart disease	0.1	0.1	0.6	-0.1	0.2	-0.2	-0.3	0.1	-0.1	0.2	-0.3	0.2	0.1	0.7	0.8	-0.3	-0.1
Illnesses of siblings: Diabetes	1.1	1.3	4.1	0.4	-0.4	-2.0	-1.6	-2.0	-0.4	-1.8	-1.2	-0.6	0.9	0.4	0.8	-0.5	-1.0
Smoking status: Previous	1.3	2.0	7.3	1.4	-1.3	-1.3	-0.9	-0.3	-1.2	-0.7	-2.0	-2.3	0.2	-0.0	1.1	-1.3	-2.7
Forced expiratory volume in 1-second (FEV1), predicted	2.3	4.7	9.1	-1.6	1.1	2.3	1.5	2.0	1.8	2.6	3.0	2.5	-2.6	0.2	-2.4	1.9	3.0
Whole body fat-free mass	0.2	1.3	3.0	1.2	-1.3	1.7	-1.6	-1.0	-0.7	1.6	0.5	-0.9	-0.3	1.7	0.7	-0.7	-0.9
Leg fat-free mass (right)	0.3	1.7	3.8	1.6	-2.0	1.1	-1.5	-1.1	-1.2	0.9	-0.4	-1.6	-0.3	1.8	1.0	-1.2	-1.4
Arm fat percentage (left)	0.8	3.3	6.6	2.0	-2.6	-1.0	-2.2	-0.2	-1.8	-1.5	-2.4	-2.1	1.1	2.2	1.4	-1.7	-1.7
Average weekly red wine intake	2.0	3.0	6.6	2.4	-0.4	0.2	-0.7	0.2	-2.4	0.2	-1.8	-1.9	2.2	1.2	2.5	-2.6	-1.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	3.0	-0.3	-0.6	0.0	-1.7	-0.5	0.3	0.6	0.7	0.4	-1.6	0.7	-0.8	0.6	0.9
Mood swings	0.7	1.2	3.1	-0.6	-1.6	-0.4	1.8	1.7	1.1	-0.4	0.1	0.8	-1.4	0.3	-0.8	1.6	1.2
Loneliness, isolation	0.3	0.4	0.9	0.9	-0.6	0.4	-0.1	-0.6	-0.8	0.4	-0.9	-0.3	-0.1	0.9	0.8	-0.3	0.1
Long-standing illness, disability or infirmity	0.6	0.9	8.5	0.6	-2.9	0.5	0.2	0.9	0.1	-0.1	-0.0	-0.4	-1.6	0.2	0.2	0.5	0.0
Ever had bowel cancer screening	0.2	0.2	0.6	0.3	0.7	0.4	-0.6	0.5	-0.3	0.8	0.0	-0.2	-0.1	-0.0	0.2	-0.1	-0.8
Diabetes diagnosed by doctor	1.5	2.4	5.4	-1.5	0.6	0.1	1.5	0.6	2.3	0.7	1.6	1.7	-1.8	-1.5	-1.8	2.3	1.8
Ever had stillbirth, spontaneous miscarriage or termination	4.0	4.3	8.3	2.5	-0.5	-1.0	-1.9	-0.8	-2.6	-0.7	-2.6	-1.9	2.9	2.6	2.4	-2.5	-2.1
Friendships satisfaction	1.1	1.3	5.0	-1.0	1.2	0.2	0.5	-0.1	1.6	0.3	1.0	1.2	-1.0	-2.2	-1.7	1.2	0.8
Qualifications: nursing, teaching	0.9	1.4	4.3	-1.5	2.1	-0.2	0.4	1.2	1.2	0.2	1.0	1.2	-0.4	-1.9	-1.4	1.0	0.7
Commuting to job workplace: Walk	0.1	0.1	0.5	0.1	-0.3	0.0	0.2	-0.3	0.3	-0.2	0.3	-0.3	-0.1	-0.7	0.3	0.2	-0.2
Eye problems/disorders: Cataract	0.5	0.6	2.5	1.1	-1.6	-0.0	-1.0	0.1	-0.4	-0.4	-0.7	-1.4	-0.4	-0.4	0.5	-0.2	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	4.6	1.7	-2.1	-0.7	-1.4	-0.8	-1.2	-0.6	-1.2	-0.9	-0.0	0.7	0.7	-1.4	-0.7
Medication for cholesterol	0.6	0.9	3.3	-0.3	0.1	-1.6	-0.2	-0.5	-0.0	-1.8	-0.8	-0.9	0.9	-1.5	-0.6	-0.3	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	3.6	1.4	-1.9	-1.3	-0.8	-0.5	-1.0	-1.6	-1.6	-1.2	1.0	0.6	1.2	-1.0	-1.4
Back pain experienced in last month	0.3	0.4	1.9	0.4	-1.3	-0.5	-1.4	-0.2	-0.0	0.1	0.1	-0.1	-1.0	-0.0	-0.1	0.4	-0.6
Mineral and other dietary supplements	2.8	3.8	8.2	-2.3	1.8	-0.4	1.3	1.5	2.5	0.2	2.3	1.0	-2.0	-2.6	-2.9	2.4	2.0
Breast cancer (self-reported)	0.4	0.5	1.6	0.7	0.1	0.9	0.1	-0.2	-0.8	1.2	0.1	0.7	-0.7	0.4	0.5	-0.6	1.3
Asthma (self-reported)	1.6	3.3	10.2	-2.1	1.1	-2.5	0.7	-1.9	2.1	-3.2	0.5	1.3	1.1	-2.6	-0.8	1.1	1.9
Osteoporosis (self-reported)	0.7	0.9	4.1	0.2	-0.4	1.3	2.0	1.1	0.2	1.6	0.6	0.1	-1.2	0.7	0.2	0.7	-0.1
Osteoarthritis (self-reported)	2.0	2.6	11.2	0.7	-3.3	-2.0	-0.5	-0.7	-0.9	-2.8	-1.6	-2.2	0.7	-0.9	1.1	-1.0	-0.8
Medication: Aspirin	0.7	1.0	2.6	-1.3	-0.9	-1.4	0.3	0.4	1.6	-0.8	0.5	-0.4	-1.0	-1.2	-0.9	1.5	0.3
Medication: Gliclazide	0.4	0.5	4.2	0.5	0.3	0.4	-0.0	-0.3	-0.6	0.1	-0.6	-0.7	0.4	0.5	0.1	-0.5	2.0
Illnesses of father: None of the above (group 1)	0.8	0.9	2.7	1.1	-1.7	-0.5	-0.0	-1.2	-0.9	-0.7	-1.1	-1.4	0.6	-0.3	0.8	-0.8	-1.1
Smoking status: Current	0.5	0.8	1.9	1.2	0.1	-0.9	-0.4	1.0	-0.9	-1.0	-1.2	-0.8	0.7	0.3	0.9	-1.4	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	4.9	0.4	2.0	1.5	-0.9	0.6	-1.7	2.2	-1.3	-1.9	1.3	0.9	0.6	-1.3	-1.0
Whole body water mass	0.2	1.4	3.1	1.3	-1.2	1.8	-1.7	-1.0	-0.8	1.6	0.4	-1.0	-0.3	1.8	0.7	-0.8	-1.0
Leg predicted mass (right)	0.3	1.5	3.4	1.5	-1.8	1.1	-1.5	-1.1	-1.0	0.9	-0.3	-1.4	-0.3	1.7	0.9	-1.1	-1.3
Arm fat mass (left)	0.8	3.1	6.2	2.2	-2.5	-0.2	-2.4	-0.4	-1.9	-0.6	-1.9	-2.0	0.8	2.5	1.4	-1.7	-1.7
Number of self-reported non-cancer illnesses	1.8	3.2	13.1	1.3	-3.3	-2.5	0.3	0.5	-0.1	-3.6	-2.2	-2.0	0.5	-0.7	0.8	-0.9	-1.2
Average weekly champagne plus white wine intake	2.8	3.9	10.7	-2.0	1.2	1.4	1.7	1.7	2.2	1.5	3.3	2.9	-1.5	-1.2	-2.1	2.5	0.4
Miserableness	1.7	2.9	7.6	-1.7	0.3	1.0	2.8	1.8	2.0	0.8	1.1	2.2	-1.3	-1.1	-1.7	2.2	2.2
Guilty feelings	0.5	0.7	2.1	-1.1	-0.2	0.1	0.9	0.4	0.7	-0.0	0.9	0.8	-0.5	-0.9	-1.1	1.4	1.2
Wears glasses or contact lenses	0.3	0.3	1.1	-0.1	0.2	-0.1	1.0	-0.0	-0.2	-0.5	-0.2	0.2	1.0	-0.3	1.1	0.1	-0.9
Ever taken oral contraceptive pill	2.4	2.7	6.0	1.9	1.0	0.6	-2.0	-2.2	-1.7	-0.5	-0.9	-1.1	2.5	0.9	2.5	-1.7	-1.7
Hearing aid user	0.4	0.5	1.8	0.6	-0.2	-0.5	-1.2	-0.3	-0.4	-0.5	0.2	-1.0	0.7	0.1	0.1	-1.3	-0.6
Mother’s age at death	2.0	2.5	5.8	1.5	0.0	-1.3	-1.5	-1.6	-1.6	-1.7	-1.4	-1.2	2.3	-0.4	2.1	-2.4	-1.2
Financial situation satisfaction	0.6	0.8	2.7	-0.7	-0.1	-1.6	-0.4	-1.1	0.1	-1.5	-0.5	-0.6	-0.4	-0.7	-1.0	0.1	1.3
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.3	0.9	-1.5	-1.1	-0.5	0.5	-1.0	-1.0	-1.2	-1.0	0.8	-0.3	0.6	-0.9	-1.0
Commuting to job workplace: Public transport	0.4	0.4	2.1	0.2	-0.6	0.7	-0.3	-0.3	-0.7	0.6	0.4	0.4	0.8	0.4	0.9	-0.0	-1.4
Eye problems/disorders: Glaucoma	0.3	0.4	1.0	0.7	0.5	0.7	0.3	-0.2	-0.7	0.9	-0.3	-1.0	0.3	0.9	0.4	-0.6	-0.3
Medication: Blood pressure	0.8	1.5	3.0	-0.9	-0.1	1.1	1.7	1.2	1.2	1.1	1.7	1.6	-1.5	1.1	0.1	1.7	-0.3
Pain type(s) experienced in last month: Hip pain	1.0	1.2	7.4	1.0	-2.7	-0.1	-0.7	0.5	-0.0	0.2	0.0	-0.4	-2.6	0.2	-0.7	0.3	0.6
Supplements: Fish oil (including cod liver oil)	2.2	2.8	5.8	1.7	-0.8	0.2	-1.2	-1.3	-2.2	-0.2	-2.1	-1.8	1.8	2.4	2.2	-2.1	-1.5
High cholesterol (Self-reported)	1.2	2.2	6.8	2.0	-2.1	-2.0	-0.3	0.3	-1.3	-1.4	-2.6	-1.8	0.3	0.3	0.8	-1.9	-0.7
Medication: Bendroflumethiazide	0.3	0.5	1.9	0.6	0.1	0.3	0.4	-0.2	0.3	0.3	0.1	-0.7	-0.4	1.4	1.0	-0.3	-1.4
Medication: Paracetamol	1.3	2.0	6.1	2.3	-2.4	-0.2	-0.6	0.6	-1.9	-0.6	-1.0	-1.3	-0.6	2.5	1.1	-1.1	-0.1
Medication: Lisinopril	0.3	0.4	1.4	-0.3	0.8	0.7	0.1	0.3	0.8	0.4	0.6	1.2	0.2	0.8	-0.4	0.9	0.2
Medication: Atorvastatin	1.6	2.0	6.1	-1.9	0.4	-1.0	1.2	-0.4	2.1	-1.7	0.6	1.5	-0.1	-2.5	-1.6	1.0	1.4
Illnesses of father: High blood pressure	2.6	3.2	8.1	-2.4	2.8	1.0	-0.1	0.8	2.5	0.6	2.2	2.4	-0.8	-1.1	-2.1	2.0	1.4
Alcohol drinker status: Never	2.2	2.7	6.1	2.0	-0.3	-0.1	-0.5	-1.3	-2.4	-0.2	-2.1	-1.6	2.5	0.9	2.2	-2.4	-1.1
Ever smoked	0.5	0.9	3.4	0.9	-0.7	-0.7	0.5	0.9	-0.6	-0.7	-1.5	-1.8	-0.1	0.2	1.0	-0.9	-1.2
Basal metabolic rate	0.3	1.6	4.3	1.5	-1.7	1.6	-1.7	-0.8	-1.0	1.4	0.2	-1.1	-0.3	2.1	0.8	-0.9	-1.0
Leg fat percentage (left)	0.3	1.1	3.7	1.2	-1.9	-0.3	-1.2	0.6	-0.7	-0.6	-1.2	-0.9	0.3	1.8	0.5	-0.6	-1.2
Arm fat-free mass (left)	0.2	1.3	3.1	1.2	-1.3	1.8	-1.7	-0.6	-0.6	1.7	0.6	-0.8	-0.4	1.6	0.5	-0.6	-0.8
Number of operations (self-reported)	4.0	6.0	10.7	2.3	-2.3	-2.1	-1.7	-1.6	-2.6	-3.0	-3.0	-3.3	2.6	-0.3	3.0	-3.0	-1.9
Average weekly beer plus cider intake	1.5	2.2	7.0	0.3	0.2	-1.6	-0.9	-2.7	-0.7	-1.9	-1.7	-1.3	2.0	0.2	1.6	-0.8	-2.1
Irritability	1.0	1.7	7.8	-0.4	-0.4	0.6	2.8	1.9	1.3	0.5	0.9	0.7	-2.1	0.1	-0.8	1.7	0.7
Risk taking	0.5	0.8	2.1	1.1	0.8	0.5	0.1	-0.0	-1.0	0.5	-1.2	-1.0	1.0	0.5	0.7	-1.0	-1.4
Ever had prostate specific antigen (PSA) test	0.9	1.1	4.1	1.0	-0.1	-0.9	-0.4	-0.3	-1.2	-0.9	-1.5	-2.0	0.8	1.2	0.6	-1.2	0.1
Fractured/broken bones in last 5 years	0.5	0.7	3.6	0.5	-1.2	0.8	0.2	1.9	-0.6	0.1	-0.4	-0.2	0.2	1.0	0.2	-0.1	-1.3
Age started oral contraceptive pill	0.3	0.4	2.7	0.5	-1.6	-0.0	-0.4	-0.2	-0.9	0.4	-0.1	-0.8	-0.1	-0.0	0.2	-0.2	-0.2
Diastolic blood pressure, automated reading	0.2	0.7	3.0	-0.5	0.8	-0.9	0.0	0.2	0.5	-1.7	-0.7	0.7	1.5	0.1	0.9	0.1	0.7
Ever depressed for a whole week	0.7	0.9	2.3	-0.1	0.2	1.2	0.7	1.2	0.8	1.2	1.2	1.2	-1.0	0.0	-1.2	1.5	-0.3
Unable to work because of sickness or disability	0.4	0.6	1.9	-0.1	-0.1	0.3	0.1	0.4	0.9	-0.2	-0.2	0.2	-1.0	-1.4	-1.3	0.5	1.2
Commuting to job workplace: Cycle	0.3	0.3	1.0	-0.2	-0.9	-0.6	0.6	-1.0	0.4	-0.6	-0.4	-0.4	0.2	0.2	0.8	0.1	-0.7
Myopia	0.4	0.6	1.6	1.0	0.3	-0.1	1.3	-0.0	-0.8	-0.6	-0.7	-0.3	1.2	0.3	1.2	-0.7	-1.1
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.5	0.5	0.4	1.4	-1.6	-1.3	-1.1	1.3	0.5	-0.1	0.9	-0.5	-0.1	-0.7	-0.2
Cholesterol lowering medication	0.3	0.5	1.9	-0.1	-0.5	0.1	1.0	1.4	-0.2	0.6	-0.2	1.0	-1.0	1.0	0.1	0.6	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.5	0.6	-0.9	0.3	-0.3	-1.2	-0.6	-0.6	-1.0	-0.2	0.5	0.3	0.6	-0.4	-0.4
Pain experienced in last month	0.2	0.4	1.6	-0.3	0.7	-1.2	-0.3	-0.6	-0.5	-0.6	-0.5	-0.6	1.0	0.1	0.1	-0.7	0.6
Supplements: Calcium	1.0	1.1	3.1	0.7	0.6	1.7	0.7	-0.4	-1.2	1.3	0.0	0.1	0.6	1.3	1.6	-0.6	-1.7
Basal cell carcinoma (self-reported)	2.6	3.1	6.7	-2.0	1.5	1.3	1.6	1.3	2.4	1.6	2.4	2.3	-1.4	-0.8	-1.5	2.6	0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.4	-1.4	0.8	-0.7	-0.0	0.1	1.1	-0.1	0.6	-0.1	-0.6	-1.5	-0.8	1.0	0.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	6.0	0.5	-0.0	1.0	0.7	2.5	0.8	0.5	0.4	-0.2	-1.4	1.6	-1.0	0.0	0.7
Heart disease (siblings)	0.9	1.1	5.0	-0.2	-1.6	-2.2	-1.0	-1.2	0.3	-1.6	-1.2	0.6	0.0	0.0	-0.2	0.0	-1.2
Alcohol drinker status: Previous	1.2	1.3	3.5	0.9	-0.2	1.3	0.7	1.9	-0.1	1.4	-0.0	0.1	-1.8	1.7	-1.1	0.4	1.6
Pack years of smoking	0.7	1.0	2.2	1.4	-0.4	-0.4	0.8	0.6	-1.0	-0.9	-1.0	-1.0	1.3	0.5	1.5	-1.2	-1.1
Impedance of whole body	0.2	0.8	3.8	-1.0	0.6	-0.6	1.9	1.2	0.3	-0.6	0.1	0.7	-0.0	-0.8	-0.5	0.9	1.3
Leg fat mass (left)	0.6	2.3	6.2	1.9	-2.5	-0.0	-1.9	0.0	-1.5	-0.3	-1.6	-1.6	0.6	2.2	1.1	-1.2	-1.8
Arm predicted mass (left)	0.3	1.3	3.6	1.3	-1.4	1.6	-1.9	-0.6	-0.8	1.5	0.3	-0.9	-0.2	1.7	0.6	-0.7	-1.0