[Hub]/) : Traits : Heel T-Score : ← →

chr14:52,408,380-55,125,699

Best TWAS P=1.65e-170 · Best GWAS P=1.31e-158 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BMP4 0.09 0.09 enet 6 0.09 8.5e-11 -26.8 -24.5 1.2e-132 0.95 0.00 1.00 TRUE
2 GTEx Brain Cerebellum BMP4 0.34 0.13 enet 21 0.16 1.7e-05 -26.8 -27.8 1.7e-170 0.77 0.00 0.99 TRUE
3 GTEx Whole Blood ERO1L 0.12 0.01 lasso 3 0.00 3.1e-01 -6.2 6.1 8.0e-10 -0.06 0.03 0.96 FALSE
4 GTEx Whole Blood RP11-841O20.2 0.17 0.03 enet 33 0.05 1.4e-05 -6.2 5.2 2.0e-07 -0.04 0.02 0.98 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma ERO1L 0.03 0.01 blup 57 0.02 1.5e-02 2.8 -6.2 6.6e-10 0.06 0.02 0.68 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma ERO1L 0.01 0.01 blup 57 0.01 1.7e-02 -6.2 -6.8 1.2e-11 0.05 0.01 0.87 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ERO1L 0.08 0.01 blup 57 0.03 3.8e-04 -6.5 -5.7 1.2e-08 0.06 0.01 0.96 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma ERO1L 0.02 0.03 lasso 4 0.03 6.2e-04 -6.3 -6.3 2.3e-10 0.06 0.01 0.95 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma STYX 0.06 0.00 blup 50 0.03 5.4e-04 1.6 5.2 2.3e-07 -0.04 0.02 0.66 FALSE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors ERO1L 0.13 0.03 enet 13 0.06 3.3e-03 -6.4 -5.7 1.2e-08 0.04 0.01 0.92 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma CDKN3 0.03 0.03 enet 6 0.02 7.2e-03 -6.4 -6.0 1.5e-09 0.03 0.02 0.90 TRUE
12 The Cancer Genome Atlas Thyroid Carcinoma ERO1L 0.13 0.14 blup 57 0.14 1.1e-13 -6.3 -5.9 4.7e-09 0.09 0.01 0.99 FALSE