Hub : Genes

ERO1L

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Whole Blood	0.1190	0.0370	1.0e-04	0.007	NA	-0.003	NA	0.000	6.4e-02	NA	7.1e-01	NA	3.1e-01
2	NTR	Blood	0.1164	0.0288	5.5e-14	0.014	0.057	0.063	0.059	0.045	2.3e-05	8.9e-18	1.2e-19	2.1e-18	1.8e-14
3	YFS	Blood	0.5938	0.0410	0.0e+00	0.167	0.414	0.430	0.415	0.390	3.1e-52	1.5e-148	1.6e-156	2.8e-149	8.9e-138
4	TCGA	Bladder Urothelial Carcinoma	0.0350	0.0200	7.5e-03	0.012	0.016	0.012	NA	0.013	3.1e-02	1.5e-02	2.8e-02	NA	2.6e-02
5	TCGA	Breast Invasive Carcinoma	0.0134	0.0078	7.6e-03	0.010	0.006	0.001	NA	0.005	2.4e-03	1.7e-02	1.7e-01	NA	3.1e-02
6	TCGA	Brain Lower Grade Glioma	0.0754	0.0469	5.4e-04	0.012	0.028	0.010	NA	0.017	1.6e-02	3.8e-04	2.1e-02	NA	4.5e-03
7	TCGA	Prostate Adenocarcinoma	0.0250	0.0147	9.8e-03	0.031	0.015	0.013	NA	0.028	3.3e-04	8.5e-03	1.5e-02	NA	6.2e-04
8	TCGA	Testicular Germ Cell Tumors	0.1280	0.0630	2.9e-03	0.031	0.055	0.062	NA	0.046	3.0e-02	5.3e-03	3.3e-03	NA	9.7e-03
9	TCGA	Thyroid Carcinoma	0.1270	0.0410	3.6e-13	0.141	0.142	0.139	NA	0.135	1.4e-13	1.1e-13	1.8e-13	NA	4.5e-13

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	2.5	3.9	11.1	-1.8	-2.3	-3.3	0.4	1.8	2.0	1.7	2.2	0.8
Bipolar Disorder or Schizophrenia	0.7	1.7	4.5	-1.1	-0.4	-2.1	1.1	1.4	1.6	0.9	1.6	0.6
Depressed Affect (Nagel 2018)	1.0	2.0	4.8	-1.1	-1.5	-2.2	1.1	1.2	1.2	1.3	1.6	1.2
Depression (Nagel 2018)	3.2	4.8	7.6	-2.0	-2.8	-2.2	2.0	2.5	1.9	2.1	2.4	1.6
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.9	-0.8	1.0	-1.0	0.4	1.1	1.4	0.9	1.2	0.4
Neuroticism (Nagel 2018)	0.7	1.6	4.0	-0.7	-1.5	-2.0	1.3	1.3	1.0	1.0	1.4	0.8
Schizophrenia (2018)	0.2	0.4	1.7	0.1	1.3	-0.0	1.0	0.4	0.4	-0.2	0.3	0.1
Schizophrenia vs Biploar Disorder	3.7	4.9	7.8	2.6	1.8	1.0	-1.5	-2.5	-2.8	-2.5	-2.5	-2.1
Worry (Nagel 2018)	0.4	0.9	2.7	-0.2	-0.8	-1.3	1.6	1.4	0.3	0.3	0.6	0.1
Alzheimer’s Disease (in mother)	2.1	2.5	5.4	-1.4	-2.3	-2.2	1.4	1.9	1.4	1.4	0.8	0.6
Alzheimer’s Disease (in father)	0.5	0.5	1.6	-0.3	1.3	0.7	0.9	0.2	0.7	0.5	-0.6	0.9
Alzheimer’s Disease (including proxy)	0.7	1.0	2.2	-1.1	-0.1	-0.5	1.5	1.0	1.4	1.0	0.0	1.1
Crohns Disease (2017)	0.6	1.4	3.7	0.8	-0.7	0.1	-1.1	-1.3	-1.7	-1.0	-1.9	-0.8
Irritable Bowel Disease (IBD)	1.3	3.1	5.0	1.5	-1.1	-0.2	-2.2	-1.8	-1.8	-1.8	-2.1	-2.2
Ulcerative Colitis (UC)	1.2	2.3	6.3	1.5	-1.1	-0.1	-1.8	-1.2	-1.1	-1.7	-1.5	-2.5
Major Depression (MDD)	1.7	2.1	4.9	-1.0	-2.2	-1.3	1.7	2.2	1.1	1.2	0.9	0.3
Reaction Time	0.2	0.4	1.1	0.8	0.5	0.2	1.0	0.4	0.1	-0.7	0.2	-0.7
Verbal and Numeric Reasoning (VNR)	0.4	1.0	4.7	-0.6	2.2	-0.5	0.4	0.6	1.3	0.7	0.8	0.7
Breast Cancer	0.6	1.5	3.7	1.5	0.8	1.9	-0.5	-1.2	-1.2	-1.4	-1.1	-0.9
Ovarian Cancer	2.3	3.1	6.0	-1.7	-1.7	-2.5	0.9	1.5	1.7	1.8	2.0	1.6
Prostate Cancer	0.9	1.3	5.1	-0.3	-2.3	-0.8	-1.8	-1.4	-0.4	0.2	0.2	0.6
Age at First Birth	1.0	1.4	4.8	-0.7	-2.2	-1.6	1.2	1.5	0.7	0.8	0.1	0.2
Bipolar Disorder (2011)	1.2	1.1	3.2	-0.8	-1.3	-1.8	0.4	1.1	1.3	0.8	1.0	0.3
Body Mass Index (BMI) (2010)	0.2	0.3	1.1	-0.6	0.6	-1.1	0.2	0.3	0.4	0.7	0.3	0.3
Coronary Artery Disease (CAD)	0.9	1.0	5.5	-0.4	-1.1	-2.4	-1.1	-0.3	0.4	0.6	0.8	0.1
Crohns Disease (2012)	0.8	1.3	2.4	0.9	0.5	0.1	-1.3	-1.5	-1.3	-1.1	-1.6	-1.0
Mean Putamen Volume	0.3	0.4	0.7	-0.9	0.8	0.8	-0.2	0.3	0.7	0.8	0.1	0.4
Fasting Glucose	0.5	0.6	1.3	-0.9	0.3	-0.2	1.0	1.1	0.8	1.0	0.4	0.4
HbA1C	1.1	1.2	2.1	-1.4	1.3	-0.2	0.5	1.1	1.1	1.4	1.2	1.0
HDL Cholesterol	0.2	0.4	0.9	-0.4	-0.9	-0.7	0.5	0.9	0.7	0.3	0.7	-0.0
LDL Cholesterol	0.1	0.1	0.5	0.4	-0.3	-0.3	-0.2	-0.2	-0.1	-0.7	0.1	-0.5
Lupus	2.2	3.3	7.2	-1.9	-1.8	-1.5	2.3	2.7	1.4	1.9	1.2	1.2
Neuroticism (2016)	0.2	0.3	1.7	0.6	-1.3	-0.2	0.5	0.2	0.0	-0.2	-0.4	-0.3
Primary Biliary Cirrhosis	4.2	6.0	11.2	-2.6	-0.7	-3.4	1.3	2.4	3.0	2.6	3.2	1.6
Rheumatoid Arthritis	0.2	0.3	1.0	0.1	1.0	0.1	0.8	0.7	0.2	-0.2	0.1	-0.3
Schizophrenia (2014)	0.1	0.2	0.9	0.3	1.0	-0.8	0.2	0.1	0.1	-0.4	0.1	-0.4
Triglycerides	0.1	0.2	0.4	0.3	0.3	0.6	-0.6	-0.4	-0.7	-0.3	-0.5	-0.4
Type 2 Diabetes (T2D) (2012)	0.9	1.0	3.2	0.6	-0.3	-1.8	-1.4	-0.9	-1.0	-0.7	-0.6	-1.0
Ulcerative Colitis	0.6	0.8	3.3	0.6	-0.1	-0.5	-1.5	-0.5	-0.4	-0.8	-0.6	-1.8
Blood Eosinophil Count	0.0	0.2	0.6	0.3	-0.5	-0.4	-0.6	-0.7	-0.7	-0.4	-0.4	0.0
Blood Platelet Count	0.1	1.0	5.3	0.7	2.3	0.2	-0.7	-0.9	0.7	-0.7	0.8	-0.3
Blood Red Count	0.1	1.1	5.5	0.4	-1.4	-2.3	-0.8	-0.3	-0.5	-0.5	0.3	-0.7
Blood White Count	0.2	1.2	2.0	0.8	-1.4	-1.4	-1.1	-1.1	-1.3	-0.9	-0.7	-1.0
Heel T-Score	3.8	29.9	46.0	6.1	2.5	1.2	-6.2	-6.8	-5.7	-6.3	-5.7	-5.9
BMI	0.3	2.0	7.7	-1.0	-2.6	-2.8	-0.6	0.6	0.6	1.0	0.6	-0.2
Height	0.1	2.2	6.4	-1.8	0.5	-2.5	-1.0	-0.2	1.3	1.8	1.4	1.7
Waist Hip Ratio (WHR)	0.3	1.1	6.9	0.9	2.6	-0.6	-0.5	-0.6	-0.0	-0.7	-0.8	-0.7
Systolic Blood Pressure	0.3	1.7	8.3	0.1	-0.4	0.1	2.9	1.9	1.6	-0.1	-0.4	0.8
Smoking Status	0.4	0.9	2.8	0.8	1.0	-0.5	-1.7	-1.4	-0.2	-0.6	0.5	-0.7
Allergy or Eczema	0.2	0.6	1.9	0.5	-0.1	-0.8	-1.4	-1.4	-0.7	-0.4	-0.3	-0.2
Cardiovascular Disease	0.8	2.5	4.8	-1.4	0.1	-1.7	1.6	1.6	2.2	1.5	1.7	1.7
Hypothyroidism (self reported)	0.7	1.6	3.8	-1.9	-0.6	-0.2	0.4	1.1	1.3	1.9	1.5	1.2
Respiratory disease	0.1	0.2	0.4	0.6	-0.2	-0.3	0.5	0.3	0.3	-0.4	-0.7	-0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.6	-0.6	0.6	-0.7	-0.4	0.2	0.4	0.5	0.8	-0.1
Lung FEV1/FVC ratio	0.2	1.2	4.9	-0.8	-2.2	-1.4	-0.2	0.9	0.7	0.8	1.2	-0.0
Lung FVC	0.0	0.2	0.8	0.4	-0.9	-0.5	0.6	0.4	0.2	-0.3	-0.1	-0.2
Neuroticism	0.3	0.7	3.0	-0.3	-0.3	-1.7	0.7	0.7	0.9	0.4	0.9	0.5
Chronotype (morning person)	1.9	4.5	14.8	-1.9	-3.1	-3.8	0.1	1.7	1.7	1.9	1.7	0.6
Hair Pigment	0.0	0.7	1.3	1.0	0.7	-0.4	1.1	0.8	0.3	-1.0	-0.6	-1.0
Tanning	0.0	0.4	0.8	-0.7	0.9	0.3	0.3	0.2	0.8	0.7	0.4	0.8
Hand grip strength (left)	3.1	8.1	15.0	-3.7	0.6	-2.1	1.8	2.5	2.7	3.7	3.9	2.9
Number of treatments/medications taken	0.4	0.7	3.3	-0.8	-0.5	-1.8	0.4	0.9	0.7	0.8	0.5	0.3
Average weekly spirits intake	0.8	1.0	5.2	-0.7	-0.7	-2.3	-0.3	0.2	1.0	0.6	1.2	0.4
Sensitivity / hurt feelings	0.4	0.6	1.6	-0.3	-0.7	-0.8	1.1	0.7	0.8	0.2	1.3	0.6
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.7	-1.0	-0.3	-1.2	1.2	1.4	1.2	1.2	1.7	0.9
Hearing difficulty/problems: Yes	0.4	0.6	2.3	0.6	-1.5	-0.4	-0.7	-0.5	-0.9	-0.4	-0.4	-0.6
Relative age of first facial hair	0.2	0.4	1.5	-0.4	1.2	-0.3	-0.1	0.1	0.9	0.4	1.1	0.2
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.8	-0.7	-0.4	-0.9	0.5	0.8	0.8	0.7	0.8	0.4
Ever used hormone-replacement therapy (HRT)	1.5	1.8	7.7	0.9	-2.8	-1.8	-1.1	-0.5	-0.7	-0.8	-0.4	-1.6
Ever had hysterectomy (womb removed)	1.3	1.5	3.1	1.3	0.2	1.1	-1.0	-1.3	-1.1	-1.5	-1.8	-1.1
Systolic blood pressure, automated reading	0.5	1.4	5.3	-0.3	-0.6	-1.0	2.3	1.8	1.5	0.2	-0.3	0.6
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	4.4	0.4	-1.6	-2.1	-1.3	-0.5	-0.3	-0.4	-0.1	-0.6
Angina	0.8	1.0	4.3	0.5	-1.4	-2.1	-1.1	-0.5	-0.4	-0.4	-0.9	-0.7
Medication for hormone replacement therapy	0.5	0.6	2.5	0.2	-0.9	0.2	-1.6	-1.1	-0.6	-0.2	-0.4	-0.6
Vitamin and mineral supplements	0.9	1.2	4.8	0.2	-2.2	-1.7	-1.4	-0.5	-0.4	-0.4	0.1	-0.7
Supplements: Zinc	0.4	0.4	1.3	0.3	-0.1	0.9	-1.0	-1.1	-0.6	-0.3	0.1	0.1
Medication: Co-codamol	1.3	1.5	3.1	-1.3	-1.7	-0.6	1.8	1.5	0.3	1.2	0.4	1.3
Medication: Metformin	0.5	0.7	3.1	0.1	-0.3	-0.7	-1.7	-1.1	-0.8	-0.1	0.5	-0.5
Diabetes (father)	0.3	0.3	2.0	-0.1	-0.7	-1.4	-0.1	0.0	0.5	-0.1	0.4	-0.2
Diabetes (mother)	0.3	0.4	1.2	0.7	-0.6	-0.2	0.3	0.2	-0.3	-0.6	-0.7	-1.1
Severe depression (siblings)	0.9	1.1	4.9	-0.4	-0.7	0.5	2.2	1.4	0.7	0.6	0.3	0.9
Pack years adult smoking proportion	0.1	0.2	0.9	-0.2	-1.0	-0.2	0.5	0.4	0.0	0.3	0.2	0.3
Impedance of leg (right)	0.2	0.8	1.9	1.2	-0.6	-0.5	-0.3	-0.9	-1.4	-1.3	-0.7	-0.6
Leg fat-free mass (left)	0.4	2.0	3.5	-1.9	-1.4	-1.9	-0.9	0.6	1.4	1.8	1.5	0.6
Trunk fat percentage	0.9	3.7	20.7	0.3	-4.5	-2.3	-1.7	-1.0	-1.3	-0.4	-0.6	-1.0
Hand grip strength (right)	4.1	11.1	22.2	-4.3	-0.7	-2.7	1.9	3.1	3.2	4.3	4.7	3.2
Townsend deprivation index at recruitment	0.5	0.8	4.0	0.8	2.0	1.1	-0.1	-0.2	0.3	-0.5	-0.3	-0.6
Current tobacco smoking	0.6	0.9	3.9	-0.9	-0.1	-0.7	-0.9	-0.3	1.0	0.9	2.0	0.6
Average weekly fortified wine intake	0.8	0.9	2.4	-0.8	-0.3	-1.1	-0.2	0.3	1.5	0.7	1.6	0.7
Maternal smoking around birth	0.5	0.7	3.4	0.4	-0.5	1.8	-0.3	-0.6	-1.0	-0.3	-0.7	-0.1
Fed-up feelings	1.0	1.8	3.0	-1.4	0.1	-0.3	1.1	1.4	1.7	1.7	1.6	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	4.5	6.1	7.9	-2.4	-1.9	-2.5	2.4	2.8	2.7	2.6	2.6	2.2
Relative age voice broke	0.5	0.8	4.3	0.8	2.1	0.6	-0.0	-0.4	-0.2	-1.0	-0.6	-0.8
Taking other prescription medications	0.3	0.4	1.1	0.7	0.3	-0.8	0.6	0.3	0.3	-0.7	-1.0	-0.6
Age when periods started (menarche)	0.6	1.3	5.9	0.7	0.6	2.4	-1.0	-1.1	-1.2	-0.7	-0.8	-0.7
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	4.2	-0.7	-2.1	-1.5	-0.3	0.3	0.2	0.6	0.6	0.2
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.3	10.5	3.1	0.9	0.7	-3.2	-3.2	-2.7	-3.2	-2.8	-3.0
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.5	-0.8	-0.4	0.9	1.2	0.9	0.4	0.9	0.4	1.2
Qualifications: CSEs or equivalent	0.2	0.2	0.6	-0.2	-0.7	0.1	0.7	0.2	-0.1	0.2	0.4	0.8
Serious illness, injury or assault to yourself	1.6	1.9	4.2	-1.4	-0.9	-2.0	0.5	1.3	1.5	1.6	1.5	1.1
High blood pressure	0.9	2.5	3.7	-1.6	-1.6	-1.9	1.3	1.6	1.8	1.5	1.5	1.5
Hayfever, allergic rhinitis or eczema	0.2	0.3	1.2	0.5	-0.3	-0.4	-1.0	-1.1	-0.5	-0.4	-0.2	-0.1
Multivitamins +/- minerals	1.9	2.4	3.7	1.7	1.8	1.9	-0.5	-1.5	-1.4	-1.5	-1.9	-1.1
Stomach or abdominal pain in last month	0.2	0.3	1.0	0.5	0.8	0.4	0.2	-0.1	-0.3	-0.3	-1.0	-0.2
Supplements: Glucosamine	0.2	0.2	0.4	0.6	-0.7	0.4	-0.2	-0.2	-0.5	-0.5	-0.6	-0.6
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.5	1.0	0.6	0.6	-1.9	-1.6	-1.0	-1.1	-0.6	-1.3
Medication: Atenolol	0.4	0.5	1.3	0.1	-1.1	-0.8	1.1	0.7	0.5	-0.1	-0.6	0.1
Medication: Levothyroxine sodium	1.0	1.8	3.1	-1.5	-1.4	-1.8	0.1	1.2	1.2	1.6	1.6	0.6
Sitting height	1.0	7.3	13.5	-3.7	-1.5	-2.7	-0.1	1.7	2.9	3.6	3.5	2.6
Chronic bronchitis/emphysema (father)	1.6	1.8	7.3	-0.7	-2.4	-2.7	0.2	1.0	0.2	0.9	1.1	0.1
High blood pressure (mother)	0.2	0.2	0.7	-0.6	-0.2	-0.2	0.0	0.3	0.4	0.7	0.8	0.6
Body mass index (BMI)	0.4	1.9	10.6	-0.6	-3.2	-2.3	-0.8	0.2	-0.1	0.6	0.1	-0.5
Impedance of leg (left)	0.2	0.9	2.1	1.4	-0.0	0.2	-0.2	-1.1	-1.4	-1.4	-0.8	-0.5
Leg predicted mass (left)	0.4	2.2	3.9	-2.0	-1.4	-1.9	-0.8	0.7	1.5	1.9	1.6	0.7
Trunk fat mass	0.7	3.2	17.3	-0.4	-4.2	-2.7	-1.6	-0.6	-0.6	0.2	0.0	-0.6
Waist circumference	0.3	1.2	4.3	-0.2	-1.5	-2.1	-1.7	-0.7	-0.2	0.2	-0.2	-0.6
Number of incorrect matches in round	2.0	3.4	6.1	2.4	1.9	1.6	-0.5	-1.7	-2.0	-2.5	-1.5	-1.7
Past tobacco smoking	0.1	0.3	0.9	-0.8	-0.4	-0.2	0.5	0.3	0.1	0.6	-0.1	1.0
Alcohol usually taken with meals	1.3	2.2	7.2	0.7	-0.8	-1.9	-2.7	-1.8	-1.2	-0.8	-0.5	-1.4
Nervous feelings	0.5	0.9	4.6	-0.3	0.8	0.3	2.1	1.2	0.9	0.3	-0.1	0.9
Frequency of tenseness / restlessness in last 2 weeks	4.3	6.7	9.3	-2.6	-1.5	-1.9	2.7	3.1	2.8	2.9	2.9	2.5
Hearing difficulty/problems with background noise	0.3	0.4	2.4	0.3	-1.6	-0.5	0.7	0.6	-0.1	-0.0	-0.2	-0.4
Hair/balding pattern: Pattern 2	0.0	0.1	0.2	0.2	0.1	0.3	0.1	0.3	-0.2	-0.2	-0.3	-0.4
Had menopause	0.6	0.7	1.8	1.0	0.5	-0.0	-0.4	-0.4	-0.8	-1.0	-1.1	-1.3
Had other major operations	2.6	3.2	7.2	-1.6	-2.4	-2.7	1.2	1.7	1.4	1.6	1.8	1.1
Forced vital capacity (FVC)	0.8	2.9	5.3	-2.1	-0.8	-1.1	1.0	1.5	1.8	2.2	2.3	1.8
Heel bone mineral density (BMD) T-score, automated (right)	4.7	10.8	17.6	3.8	0.9	0.6	-3.9	-4.2	-3.4	-3.9	-3.1	-3.5
Ever unenthusiastic/disinterested for a whole week	1.6	1.9	3.2	-1.3	0.1	-0.8	1.8	1.7	1.7	1.5	1.3	1.6
Qualifications: None of the above	0.3	0.7	2.3	0.7	1.5	1.1	0.6	-0.3	-0.6	-0.6	-1.0	-0.0
Financial difficulties in last 2 years	0.3	0.4	1.2	-0.2	0.1	-1.1	-0.9	-0.6	-0.1	0.3	1.0	0.2
Mouth/teeth dental problems	0.4	0.6	3.2	-0.9	-1.8	0.0	-0.1	0.5	0.1	0.8	0.9	0.2
Heart attack	0.4	0.5	1.7	0.4	-1.2	-1.3	0.3	0.6	-0.1	-0.3	-0.7	-0.8
Allergy	0.3	0.7	1.2	-0.9	1.0	0.7	1.1	1.1	0.4	0.7	0.6	0.5
Pain all over the body in last month	2.8	3.0	5.8	-1.7	0.1	-0.9	1.6	2.1	2.4	1.8	2.2	1.5
Diabetes (self-reported)	0.6	0.9	2.9	-1.0	-1.3	-1.7	-0.3	0.5	0.6	0.9	0.8	0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	-0.2	0.1	-0.0	-0.5	-0.6	-0.1	0.3	0.1	0.6
Medication: Ramipril	0.2	0.2	0.9	0.2	0.6	0.5	0.3	0.1	-0.5	-0.3	-1.0	-0.2
Medication: Simvastatin	0.2	0.3	1.3	0.4	-0.3	-0.3	-1.2	-0.9	-0.3	-0.4	-0.3	-0.1
Fluid intelligence score	0.3	0.6	1.9	-0.6	1.4	-0.3	0.1	0.5	1.0	0.8	0.5	0.6
Illnesses of siblings	0.5	0.7	2.7	0.2	1.6	1.1	-1.1	-0.9	-0.5	-0.3	0.2	-0.1
Neuroticism score	0.6	1.3	3.0	-0.8	-0.2	-1.7	1.2	1.3	1.1	1.0	1.3	0.7
Weight	0.6	2.8	8.3	-1.7	-2.9	-2.9	-1.1	0.5	0.8	1.6	1.1	0.3
Impedance of arm (right)	0.8	3.7	5.6	2.4	1.2	2.2	-0.9	-2.1	-2.2	-2.4	-2.0	-1.1
Arm fat percentage (right)	0.6	2.4	11.1	0.5	-3.3	-1.7	-1.6	-1.0	-1.3	-0.5	-0.9	-1.0
Trunk fat-free mass	0.7	4.0	7.2	-2.7	-0.4	-2.5	-0.1	1.5	2.4	2.7	2.3	1.4
Hip circumference	0.5	2.1	7.6	-1.5	-2.8	-2.1	-0.7	0.3	0.6	1.4	1.3	0.5
Time employed in main current job	0.3	0.3	1.0	-0.3	-1.0	0.5	0.1	-0.2	-0.8	0.4	-0.3	0.7
Alcohol intake versus 10 years previously	2.5	3.7	5.7	2.3	2.2	1.3	-1.2	-1.7	-1.9	-2.1	-2.4	-2.0
Father’s age at death	0.5	0.7	1.1	-0.9	0.4	0.5	0.7	0.8	1.0	0.9	1.0	0.9
Worrier / anxious feelings	0.7	1.3	3.6	-0.8	-1.3	-1.9	0.8	1.3	0.8	1.0	1.4	0.3
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	4.5	-1.4	-1.2	-2.1	0.8	1.5	1.6	1.5	2.0	1.0
Falls in the last year	0.1	0.1	0.4	0.4	-0.4	-0.5	-0.6	-0.3	-0.3	-0.0	-0.1	-0.3
Hair/balding pattern: Pattern 3	0.1	0.2	1.0	-0.3	-1.0	-0.4	-0.4	-0.2	-0.4	0.2	0.5	0.1
Number of live births	1.4	1.9	3.3	1.7	0.9	1.0	-1.2	-1.8	-1.5	-1.7	-1.2	-1.2
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	7.9	-2.6	-1.6	-1.3	1.5	2.2	2.3	2.7	2.8	2.0
Pulse rate	0.4	0.7	2.8	0.0	-1.7	-1.3	-0.5	0.1	-0.2	-0.1	-0.7	-1.0
Happiness	5.3	6.5	8.8	-2.9	-1.7	-2.9	2.0	2.7	2.6	3.0	2.4	2.4
Noisy workplace	1.3	1.6	3.9	-1.2	-2.0	-1.5	1.0	1.2	1.5	1.0	0.9	0.7
Qualifications: A levels/AS levels or equivalent	0.6	1.4	5.4	-0.9	-2.1	-2.3	-0.4	0.8	0.2	0.8	0.8	-0.3
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.6	-1.4	0.8	0.1	0.8	1.4	1.2	1.6	0.9	1.1
Mouth/teeth dental problems: Dentures	0.4	0.6	1.9	1.0	1.4	-0.1	-0.2	-0.8	-0.3	-0.9	-0.9	-0.3
Asthma	0.2	0.4	1.1	1.0	-0.3	0.5	0.1	-0.2	-0.4	-0.7	-1.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.9	0.5	1.0	0.4	-0.6	-0.3	-0.3	-0.6	-0.4	-0.8
Medication: Cholesterol lowering	0.3	0.5	0.7	0.7	-0.9	0.5	-0.9	-0.8	-0.6	-0.6	-0.6	-0.5
Depression (self-reported)	0.1	0.1	0.5	0.6	-0.4	-0.1	-0.3	-0.1	-0.0	-0.5	-0.2	-0.7
Medication: Lansoprazole	0.3	0.3	0.6	-0.5	0.3	-0.3	0.7	0.8	0.7	0.5	0.7	0.2
Prospective memory result	0.1	0.2	0.7	0.4	0.8	0.2	-0.1	-0.6	0.1	-0.5	-0.2	-0.2
Lung cancer (father)	0.3	0.3	0.7	0.7	-0.3	-0.6	0.1	0.0	-0.8	-0.6	-0.9	-0.6
Illnesses of mother	1.2	1.5	5.9	0.9	2.4	1.0	-1.2	-1.2	-1.0	-0.9	-0.6	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	4.9	-2.2	-0.8	-0.9	1.2	1.7	2.1	2.2	1.8	1.7
Pulse wave Arterial Stiffness index	1.6	1.9	3.7	1.9	-0.4	-0.3	-1.1	-1.6	-1.1	-1.9	-1.9	-1.1
Impedance of arm (left)	0.5	2.5	3.8	1.9	0.6	2.0	-0.7	-1.7	-1.8	-1.9	-1.7	-0.9
Arm fat mass (right)	0.5	2.1	10.4	-0.3	-3.2	-2.3	-1.4	-0.4	-0.5	0.2	-0.1	-0.7
Trunk predicted mass	0.7	3.9	7.2	-2.7	-0.5	-2.4	-0.1	1.5	2.4	2.7	2.3	1.4
Standing height	0.3	3.1	5.8	-2.4	0.3	-1.8	-0.8	0.5	2.0	2.3	2.4	1.7
Length of working week for main job	0.2	0.2	0.8	-0.4	0.4	-0.5	0.9	0.5	-0.2	0.5	0.0	0.5
Exposure to tobacco smoke at home	0.3	0.3	1.2	0.2	0.6	0.5	-1.1	-1.0	-0.2	-0.2	-0.1	-0.4
Breastfed as a baby	0.8	1.0	5.2	0.9	1.0	2.3	0.6	-0.1	-0.3	-1.0	-0.8	-0.6
Tense / ‘highly strung’	2.0	3.3	6.3	-1.7	1.0	-1.3	2.4	2.5	2.1	1.8	1.7	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	4.0	6.1	8.5	-2.4	-2.9	-2.1	2.0	2.8	2.8	2.5	2.6	1.9
Hair/balding pattern: Pattern 4	0.8	2.0	4.5	1.6	-0.0	1.6	-0.7	-1.5	-1.6	-1.6	-2.1	-0.8
Birth weight of first child	1.0	1.8	5.0	-1.8	-2.2	-1.1	0.3	0.5	0.8	1.7	0.7	1.5
Peak expiratory flow (PEF)	2.2	5.2	7.2	-2.7	-2.6	-1.1	1.8	2.4	2.3	2.7	2.6	1.9
Pulse wave reflection index	0.7	0.9	1.6	1.2	1.2	1.3	-0.4	-1.0	-0.3	-1.0	-0.9	-0.3
Ever highly irritable/argumentative for 2 days	3.0	3.6	4.8	-1.8	-0.9	-1.5	2.2	2.2	2.2	2.0	2.0	1.9
Loud music exposure frequency	0.5	0.6	2.3	-0.5	-0.3	-0.8	1.5	1.2	0.4	0.4	0.3	0.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.0	4.0	0.3	-2.0	-0.1	-1.3	-0.7	-1.3	-0.3	-0.5	-1.0
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	-0.8	0.8	-0.4	-0.2	0.1	0.5	0.9	1.1	0.8
Blood clot in the leg (DVT)	0.4	0.5	1.2	0.8	0.7	0.2	-0.6	-0.7	-0.3	-0.8	-1.1	-0.7
Medication: Paracetamol	0.5	0.8	1.4	1.1	1.2	0.7	-0.5	-1.1	-0.9	-1.1	-0.7	-0.7
Headache pain in last month	0.7	1.2	2.1	1.2	0.5	0.3	-1.5	-1.3	-1.0	-1.2	-1.0	-1.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.1	0.4	1.5	1.5	0.3	-0.1	-0.3	-0.4	-0.3	-0.5
Glaucoma (self-reported)	0.5	0.6	2.0	0.1	-0.4	-1.4	-1.3	-0.4	-0.3	-0.2	-0.4	-0.9
Gout (self-reported)	0.8	1.2	4.8	0.7	2.2	1.6	0.2	-0.4	0.2	-0.4	-1.5	-0.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	2.0	-1.4	-0.1	0.0	-0.0	0.6	1.0	1.4	1.3	0.9
Medication: Amlodipine	1.3	1.8	4.1	-1.5	-1.2	-0.9	0.8	1.3	1.2	1.4	2.0	1.2
Medication: Ventolin 100micrograms inhaler	1.4	1.7	3.5	1.8	-0.4	-0.6	-1.1	-1.5	-1.1	-1.6	-1.9	-1.1
Birth weight	0.4	0.9	1.8	-1.0	1.1	0.5	1.0	0.6	1.2	1.0	0.5	1.4
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.5	0.2	-0.5	0.7	0.7	0.6	-0.2	-0.0	-0.3	-0.5
High blood pressure (siblings)	1.0	1.4	4.5	-0.9	-2.1	-1.8	0.8	1.2	0.7	1.0	0.8	0.3
Forced vital capacity (FVC), Best measure	0.3	1.3	2.6	-1.5	0.3	-0.4	0.5	0.9	1.4	1.6	1.2	1.3
Body fat percentage	0.9	3.5	19.1	0.3	-4.4	-2.4	-1.6	-0.8	-1.3	-0.4	-0.7	-1.0
Leg fat percentage (right)	0.9	3.4	17.0	0.1	-4.1	-3.1	-1.3	-0.4	-1.1	-0.2	-0.3	-0.9
Arm fat-free mass (right)	0.9	4.5	7.7	-2.8	-1.5	-2.8	-0.2	1.6	2.3	2.7	2.4	1.2
Exposure to tobacco smoke outside home	1.9	2.5	3.9	1.9	0.8	1.7	-1.0	-1.3	-1.5	-1.8	-2.0	-1.9
Comparative body size at age 10	0.1	0.3	1.6	-0.1	0.1	-0.1	-1.2	-0.6	-0.5	0.4	0.2	-0.3
Number of full brothers	0.5	0.6	1.2	1.0	0.5	-0.1	-0.0	-0.8	-1.1	-1.1	-0.7	-0.7
Worry too long after embarrassment	0.6	0.9	3.9	-0.4	-1.3	-2.0	-0.5	0.2	0.8	0.5	1.2	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	5.4	-1.9	-1.0	-0.8	1.7	2.3	1.8	2.1	1.6	1.4
Wheeze or whistling in the chest in last year	0.5	1.0	1.8	1.3	-0.2	0.5	-1.2	-1.1	-0.7	-1.1	-1.0	-1.1
Number of children fathered	0.9	1.0	3.0	-0.6	-0.2	-1.7	1.0	1.2	1.3	0.6	0.9	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.5	0.5	-0.7	-0.4	-0.6	-0.5	-0.5	-0.5	-0.5	-0.5
Age at first live birth	0.2	0.3	0.7	0.2	-0.9	-0.7	-0.3	0.0	-0.5	-0.2	-0.8	-0.6
Pulse wave peak to peak time	1.8	2.1	4.5	-2.0	0.4	-0.0	1.0	1.6	1.3	2.0	2.1	1.2
Health satisfaction	1.7	2.2	3.6	-1.7	-1.3	-1.9	1.2	1.5	1.5	1.6	1.0	1.3
Shortness of breath walking on level ground	3.0	3.5	4.6	-1.9	-0.9	-2.1	1.7	2.0	2.1	2.0	1.9	1.9
Qualifications: College or University degree	0.1	0.4	2.1	-0.1	0.5	-0.9	-1.5	-0.4	-0.1	0.1	-0.2	-0.6
Eye problems/disorders: None of the above	0.5	0.6	1.7	-0.2	-0.8	1.1	1.3	0.6	0.1	0.2	1.0	0.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	-0.7	0.2	-0.5	0.1	0.4	0.3	0.6	0.8	0.2
Emphysema/chronic bronchitis	0.4	0.5	1.2	1.1	1.0	0.5	0.0	-0.4	-0.1	-0.9	-0.7	-0.7
Medication for pain relief, constipation, heartburn	0.9	1.5	4.0	-1.1	0.7	2.0	1.3	0.7	0.7	1.1	0.6	1.9
Neck or shoulder pain in last month	1.4	2.0	3.6	1.4	-1.6	-0.7	-1.9	-1.6	-1.0	-1.4	-0.8	-1.6
Medication: Blood pressure	0.7	1.2	5.7	-0.7	-1.7	-2.4	-0.2	0.2	0.5	0.7	0.6	0.8
Angina (self-reported)	0.8	1.1	3.1	0.8	-1.1	-1.8	-1.2	-0.7	-0.5	-0.6	-1.1	-1.0
Migraine (self-reported)	1.3	1.7	3.4	1.3	-0.4	0.4	-1.8	-1.6	-1.5	-1.3	-0.8	-1.5
Medication: Ibuprofen	0.1	0.1	0.8	-0.3	0.9	0.1	0.0	0.3	0.3	0.2	0.4	-0.1
Medication: Allopurinol	0.7	0.9	5.8	0.2	2.4	0.8	0.1	-0.1	0.2	-0.2	-1.2	0.1
Medication: Omeprazole	2.0	2.4	10.6	-1.2	-1.2	-3.3	0.3	1.4	1.5	1.4	1.3	0.4
Medication: Seretide 50 evohaler	0.6	0.7	1.7	1.3	0.3	0.5	-0.2	-1.0	-1.1	-1.2	-1.0	-0.3
Mean time to correctly identify matches	0.3	0.5	1.2	1.1	0.0	-0.6	0.7	0.1	-0.3	-1.1	-0.1	-1.0
Heart disease (mother)	1.8	2.2	4.0	1.8	-1.2	-0.1	-1.3	-1.3	-1.2	-1.7	-2.0	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	1.7	1.0	0.3	1.3	-0.5	-1.0	-0.3	-1.1	-1.0	-0.8
Whole body fat mass	0.8	3.2	16.7	-0.4	-4.1	-2.9	-1.5	-0.4	-0.5	0.2	0.0	-0.7
Leg fat mass (right)	0.7	2.8	13.0	-0.4	-3.6	-3.0	-1.5	-0.4	-0.5	0.3	0.1	-0.6
Arm predicted mass (right)	0.9	4.5	8.2	-2.7	-1.7	-2.9	-0.3	1.6	2.3	2.7	2.4	1.1
Pulse rate, automated reading	0.6	1.8	4.4	1.1	-0.7	-1.2	-1.4	-1.0	-1.3	-1.3	-1.6	-2.1
Alcohol intake frequency.	0.6	1.3	3.0	1.3	0.3	-0.9	-1.4	-1.0	-1.1	-1.3	-0.7	-1.7
Comparative height size at age 10	0.1	0.6	1.3	-0.8	0.6	-1.0	-1.1	-0.6	1.0	0.6	0.5	0.8
Number of full sisters	0.6	0.7	2.6	0.5	1.6	1.6	0.2	-0.5	-0.5	-0.6	-0.4	-0.5
Suffer from ‘nerves’	0.7	1.0	2.9	-0.2	-0.9	-1.5	1.7	1.4	1.1	0.2	0.6	0.1
Overall health rating	0.7	1.4	8.6	-0.2	-1.5	-2.9	-0.6	0.4	0.6	0.3	0.5	-0.8
Chest pain or discomfort	0.3	0.5	1.5	-0.3	0.3	-0.0	1.2	0.9	0.8	0.5	0.3	0.8
Had major operations	1.6	1.9	3.6	1.9	0.4	0.4	-1.3	-1.4	-0.8	-1.7	-1.8	-1.6
Age at last live birth	1.4	2.0	3.7	1.4	-0.4	-0.0	-1.9	-1.7	-1.7	-1.5	-1.4	-1.6
Family relationship satisfaction	0.6	0.8	1.6	-1.3	0.3	-0.3	1.1	1.0	0.6	1.2	0.6	1.0
Leg pain on walking	1.9	2.4	4.0	-1.4	-1.4	-2.0	1.2	1.6	1.9	1.5	1.7	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.8	-0.3	0.3	-0.2	0.7	-0.1	0.1	0.2	0.4	0.9
Commuting to job workplace: Car/motor vehicle	4.3	4.9	8.2	-2.6	-2.4	-0.0	2.9	2.6	1.8	2.3	1.5	2.4
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.9	0.8	-0.8	1.4	-0.3	-0.5	-1.2	-1.1	-1.1	-1.0
Medication: Aspirin	0.7	0.9	4.7	0.2	-1.5	-2.2	-0.8	0.0	0.2	-0.1	0.0	-1.0
Supplements: Vitamin C	2.5	3.0	5.4	-2.2	0.3	-0.2	1.6	1.6	1.5	2.1	2.3	2.2
Knee pain experienced in last month	0.4	0.6	1.0	0.8	-0.4	-1.0	-0.9	-0.8	-0.6	-0.8	-0.4	-0.9
Hypertension (Self-reported)	0.8	2.2	4.1	-1.4	-1.6	-2.0	1.2	1.5	1.5	1.3	1.3	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	3.9	1.3	-0.3	-0.6	-1.2	-0.9	-1.9	-1.4	-1.4	-2.0
Illnesses of father: Heart disease	0.8	1.2	7.0	0.9	-2.6	-0.7	-0.3	-0.1	-0.4	-0.9	-0.2	-1.1
Illnesses of siblings: Diabetes	0.1	0.2	0.5	0.4	0.1	0.0	-0.2	-0.7	-0.4	-0.4	-0.7	0.0
Smoking status: Previous	0.8	1.2	2.5	1.5	0.6	0.7	-0.8	-0.9	-1.0	-1.4	-0.9	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.1	-1.4	-0.2	-1.5	0.3	1.0	1.3	1.4	1.1	0.8
Whole body fat-free mass	0.6	3.3	6.2	-2.5	-0.9	-2.2	-0.3	1.2	2.1	2.5	2.1	1.1
Leg fat-free mass (right)	0.3	1.8	3.7	-1.9	-0.9	-1.3	-0.7	0.6	1.5	1.9	1.6	0.8
Arm fat percentage (left)	0.6	2.5	13.2	0.2	-3.6	-1.9	-1.4	-0.7	-1.1	-0.3	-0.8	-0.9
Average weekly red wine intake	0.3	0.4	1.4	-0.6	0.2	-1.2	-1.1	-0.4	0.1	0.6	0.3	0.3
Handedness (chirality/laterality): Left-handed	1.2	1.4	2.8	1.2	1.4	1.2	-1.1	-1.7	-1.2	-1.1	-0.6	-0.8
Mood swings	1.1	2.0	3.2	-1.4	0.9	-1.0	1.5	1.6	1.8	1.5	1.6	1.3
Loneliness, isolation	1.2	1.7	3.6	-1.1	0.0	-0.8	1.9	1.5	1.5	1.3	1.0	1.5
Long-standing illness, disability or infirmity	2.1	3.2	7.7	-1.2	-2.6	-2.8	1.3	1.8	2.1	1.3	1.2	0.9
Ever had bowel cancer screening	2.9	3.3	5.0	2.0	-0.2	1.4	-1.7	-1.9	-1.9	-2.1	-2.2	-2.1
Diabetes diagnosed by doctor	0.4	0.7	2.4	-0.1	-1.2	-1.1	-1.5	-0.7	-0.6	-0.0	-0.0	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	3.3	-1.2	-0.3	-0.7	0.5	0.8	1.8	1.2	1.5	0.9
Friendships satisfaction	2.4	3.0	4.0	-2.0	-1.2	-1.7	1.3	1.7	2.0	2.0	1.9	1.7
Qualifications: nursing, teaching	1.0	1.5	2.5	1.5	-0.7	-0.2	-1.3	-1.3	-1.4	-1.6	-1.2	-1.4
Commuting to job workplace: Walk	0.6	0.6	1.8	0.7	0.0	-0.5	-1.3	-0.9	-0.9	-0.6	-0.6	-1.0
Eye problems/disorders: Cataract	0.4	0.5	1.7	-0.5	-0.3	-1.2	-1.3	-0.3	0.2	0.6	0.7	0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	-0.2	-0.7	-0.6	0.5	0.2	-0.1	0.2	-0.5	0.4
Medication for cholesterol	0.3	0.4	1.0	-0.7	0.8	0.0	0.2	0.2	0.3	0.7	1.0	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.3	-0.6	-1.1	-0.9	0.5	0.6	0.5	0.8	0.8	0.7
Back pain experienced in last month	0.1	0.2	0.5	-0.0	-0.4	-0.6	0.5	0.6	0.2	0.0	-0.7	-0.3
Mineral and other dietary supplements	0.1	0.2	0.5	0.6	-0.4	0.1	-0.2	-0.1	-0.1	-0.7	0.0	-0.7
Breast cancer (self-reported)	1.8	2.2	3.4	-1.8	1.9	0.6	1.8	1.5	1.4	1.4	1.1	1.5
Asthma (self-reported)	0.1	0.3	0.9	0.9	-0.4	0.1	0.2	-0.0	-0.3	-0.6	-1.0	-0.3
Osteoporosis (self-reported)	0.8	1.0	3.7	-0.5	1.9	1.0	1.2	0.9	1.1	0.5	0.5	0.4
Osteoarthritis (self-reported)	0.5	0.7	2.1	-0.1	-0.6	-0.9	1.5	1.4	0.9	0.2	-0.0	0.1
Medication: Aspirin	0.7	0.9	4.5	0.1	-1.5	-2.1	-0.8	0.1	0.3	0.0	0.1	-0.8
Medication: Gliclazide	1.1	1.3	2.2	1.2	0.2	-0.3	-1.4	-1.2	-1.5	-1.1	-1.2	-1.2
Illnesses of father: None of the above (group 1)	1.4	1.7	2.9	1.2	0.1	0.2	-1.7	-1.6	-1.7	-1.3	-1.6	-1.2
Smoking status: Current	0.6	1.0	4.1	-0.9	0.2	-0.6	-0.9	-0.3	1.2	1.0	2.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	1.7	-1.2	-0.6	-1.3	1.0	1.2	0.9	1.3	0.9	1.2
Whole body water mass	0.6	3.4	6.5	-2.5	-0.8	-2.3	-0.4	1.2	2.1	2.5	2.1	1.2
Leg predicted mass (right)	0.3	1.6	3.1	-1.8	-0.8	-1.3	-0.9	0.5	1.4	1.8	1.5	0.6
Arm fat mass (left)	0.5	2.1	10.3	-0.5	-3.2	-2.4	-1.3	-0.2	-0.2	0.4	0.0	-0.6
Number of self-reported non-cancer illnesses	0.4	0.6	2.7	0.0	-1.6	-1.4	0.2	0.7	0.3	0.0	-0.0	-0.6
Average weekly champagne plus white wine intake	0.7	0.9	3.2	0.1	-1.8	-0.6	-1.8	-0.8	-0.5	-0.2	-0.2	-0.8
Miserableness	1.9	3.4	5.6	-1.9	0.2	-0.8	1.9	1.9	2.1	2.1	2.4	2.1
Guilty feelings	0.5	0.8	2.5	1.0	1.6	0.6	-0.7	-0.7	-0.4	-0.7	-1.0	-0.5
Wears glasses or contact lenses	0.5	0.6	2.0	0.2	-1.2	-1.4	-0.8	-0.3	-0.7	-0.3	0.2	-0.7
Ever taken oral contraceptive pill	1.7	1.9	3.5	-1.8	0.2	-0.1	0.9	1.1	1.5	1.9	1.8	1.7
Hearing aid user	0.8	0.9	3.3	0.9	1.8	-0.6	-1.0	-1.0	0.4	-0.7	-1.0	-0.2
Mother’s age at death	0.4	0.5	2.1	0.2	1.3	-0.1	-1.4	-0.8	0.4	-0.1	-0.3	-0.1
Financial situation satisfaction	2.3	2.9	5.7	-1.8	0.1	-0.5	2.0	1.4	1.5	1.9	2.2	2.4
Tinnitus: Yes, now most or all of the time	1.3	1.5	5.6	-1.2	-1.7	-2.4	-0.4	0.3	1.0	1.0	1.2	0.4
Commuting to job workplace: Public transport	0.6	0.7	1.5	1.2	1.2	-0.4	-0.9	-0.8	-0.1	-1.0	-0.7	-0.8
Eye problems/disorders: Glaucoma	0.7	0.8	2.2	-1.1	-0.7	-1.5	-0.5	0.6	0.8	1.1	0.9	0.3
Medication: Blood pressure	0.2	0.3	1.7	-0.0	-0.6	-1.3	0.6	0.6	0.1	-0.1	-0.2	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.8	0.4	-0.9	0.8	-0.4	-0.5	-0.2	-0.5	-0.0	-0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	-0.3	-0.4	0.3	-0.2	-0.2	-0.4	0.3	-0.2	0.2
High cholesterol (Self-reported)	0.4	0.7	1.7	0.7	1.3	1.1	-0.9	-0.9	-1.0	-0.7	-0.4	-0.3
Medication: Bendroflumethiazide	0.8	1.2	4.4	-0.6	-0.9	-2.1	1.3	1.1	0.9	0.5	0.8	0.4
Medication: Paracetamol	0.1	0.2	0.3	0.4	0.5	0.2	-0.6	-0.6	-0.3	-0.4	0.1	-0.5
Medication: Lisinopril	0.2	0.2	0.6	0.6	0.8	-0.6	-0.1	-0.5	0.2	-0.6	-0.5	-0.0
Medication: Atorvastatin	0.1	0.1	0.4	0.2	0.4	0.6	-0.4	-0.3	-0.1	-0.1	-0.3	-0.4
Illnesses of father: High blood pressure	1.1	1.4	2.6	-1.6	0.4	0.2	1.3	1.3	1.0	1.5	1.3	1.1
Alcohol drinker status: Never	0.3	0.4	2.0	0.3	-1.0	-1.4	0.3	0.0	0.1	-0.3	-0.2	-0.1
Ever smoked	0.1	0.1	0.3	0.4	0.3	-0.2	-0.2	-0.1	0.5	-0.3	0.5	-0.6
Basal metabolic rate	0.5	3.0	6.0	-2.3	-1.5	-2.5	-0.6	1.0	1.8	2.2	1.9	0.9
Leg fat percentage (left)	0.8	2.9	14.7	0.2	-3.8	-2.6	-1.3	-0.5	-1.2	-0.3	-0.3	-0.9
Arm fat-free mass (left)	0.7	3.5	6.4	-2.5	-1.0	-2.5	-0.3	1.3	2.0	2.5	2.2	1.2
Number of operations (self-reported)	1.2	1.7	6.1	-1.1	-2.5	-2.0	-0.0	1.0	1.0	1.1	1.0	0.2
Average weekly beer plus cider intake	2.2	3.2	12.2	1.1	3.0	3.5	1.1	-0.4	-0.7	-0.9	-1.9	-0.2
Irritability	1.8	3.1	8.4	-1.5	-1.2	-2.9	1.7	2.2	1.2	1.8	1.4	1.1
Risk taking	0.5	0.7	4.0	0.3	2.0	1.2	0.0	-0.7	0.5	-0.2	-0.6	0.4
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.9	-0.2	-1.2	-0.5	-1.4	-0.9	-0.6	0.2	0.0	-0.2
Fractured/broken bones in last 5 years	1.0	1.3	6.2	-0.3	-1.8	-2.5	-0.3	0.7	0.7	0.5	0.7	-0.6
Age started oral contraceptive pill	0.2	0.2	0.7	0.5	-0.1	-0.8	0.4	0.3	-0.0	-0.7	-0.3	-0.5
Diastolic blood pressure, automated reading	0.3	0.8	1.8	-0.6	-1.0	-1.4	1.1	1.2	1.0	0.4	0.3	0.3
Ever depressed for a whole week	4.1	5.1	7.4	-2.4	-1.0	-2.1	2.0	2.4	2.6	2.5	2.7	2.1
Unable to work because of sickness or disability	0.3	0.3	1.0	-0.4	0.1	0.7	1.0	0.7	0.6	0.5	-0.3	0.2
Commuting to job workplace: Cycle	0.6	0.7	5.8	0.1	2.4	-0.2	0.2	0.1	0.1	-0.2	-0.1	-0.3
Myopia	2.5	3.6	6.1	-2.1	-1.9	-0.4	2.5	2.4	1.2	1.9	1.8	2.1
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.1	0.7	1.5	1.8	-1.1	-1.1	-1.3	-0.6	-0.5	-0.8
Cholesterol lowering medication	0.2	0.3	0.7	-0.5	0.4	-0.3	0.6	0.8	0.8	0.6	0.3	0.3
Medication: Omeprazole (e.g. Zanprol)	1.6	2.0	10.2	-1.0	-0.6	-3.2	0.3	1.3	1.4	1.2	1.0	0.3
Pain experienced in last month	0.1	0.2	0.5	-0.6	0.7	0.3	-0.2	0.1	0.0	0.4	0.3	0.4
Supplements: Calcium	0.1	0.1	0.3	0.3	0.5	-0.1	0.2	-0.1	-0.2	-0.4	-0.2	0.0
Basal cell carcinoma (self-reported)	1.2	1.4	4.4	1.1	2.1	1.9	-0.6	-0.6	0.1	-1.1	-0.4	-1.2
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.2	0.5	-1.1	-1.0	0.4	0.7	-0.3	-0.4	-0.9	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	1.9	1.2	0.8	0.5	-0.9	-1.0	-0.8	-1.3	-1.4	-1.1
Heart disease (siblings)	0.4	0.5	1.2	0.9	0.6	-0.9	0.1	-0.3	-0.4	-0.8	-1.1	-0.8
Alcohol drinker status: Previous	0.5	0.6	2.4	0.2	0.5	-1.2	-1.5	-0.7	-0.2	-0.2	0.3	-0.6
Pack years of smoking	0.1	0.2	1.0	0.2	-1.0	-0.3	0.2	0.1	-0.4	-0.2	-0.2	-0.2
Impedance of whole body	0.3	1.5	2.9	1.7	0.0	1.1	-0.5	-1.5	-1.7	-1.7	-1.2	-0.6
Leg fat mass (left)	0.6	2.5	11.9	-0.3	-3.4	-2.7	-1.5	-0.4	-0.6	0.3	0.1	-0.6
Arm predicted mass (left)	0.7	3.6	7.4	-2.5	-1.3	-2.7	-0.6	1.2	1.9	2.4	2.2	1.0