[Hub]/) : Traits : Heel T-Score : ← →

chr19:11,847,615-13,960,562

Best TWAS P=2.4e-13 · Best GWAS P=7.07e-15 conditioned to 0.0531

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MAN2B1	0.05	0.03	lasso	2	0.03	5.1e-05	-4.0	5.1	2.9e-07	-0.01	0.34	0.04	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RTBDN	0.07	0.00	blup	328	0.03	8.6e-05	-2.0	7.3	2.4e-13	-0.16	0.52	0.02	TRUE
3	GTEx	Artery Aorta	MAN2B1	0.12	0.05	lasso	5	0.01	6.8e-02	-5.1	5.3	1.4e-07	-0.04	0.11	0.05	FALSE
4	GTEx	Artery Coronary	GADD45GIP1	0.40	-0.01	enet	26	0.03	4.3e-02	-2.4	-6.0	1.6e-09	0.36	0.06	0.17	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	PRDX2	0.26	-0.01	enet	41	0.06	6.9e-03	4.5	6.2	6.2e-10	-0.35	0.03	0.36	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	CTD-2659N19.10	0.25	-0.01	enet	50	0.02	6.1e-02	6.0	6.2	4.4e-10	-0.38	0.02	0.38	FALSE
7	GTEx	Cells Transformed fibroblasts	MAN2B1	0.15	0.10	enet	17	0.08	2.7e-06	-5.5	5.2	1.6e-07	-0.04	0.99	0.00	FALSE
8	GTEx	Cells Transformed fibroblasts	PRDX2	0.12	0.11	enet	18	0.12	3.0e-09	-5.1	5.7	1.2e-08	0.12	0.97	0.00	FALSE
9	GTEx	Cells Transformed fibroblasts	CTD-2659N19.10	0.09	0.01	lasso	7	0.01	8.1e-02	-5.1	5.4	5.8e-08	0.00	0.47	0.02	FALSE
10	GTEx	Colon Transverse	WDR83	0.18	0.00	enet	32	0.03	1.5e-02	-5.5	6.1	1.2e-09	-0.43	0.03	0.25	FALSE
11	GTEx	Spleen	MAN2B1	0.33	-0.01	enet	25	0.06	1.6e-02	-3.5	6.6	4.6e-11	-0.64	0.02	0.42	TRUE
12	GTEx	Testis	MAN2B1	0.18	0.07	enet	21	0.11	1.9e-05	-4.3	5.2	2.0e-07	0.00	0.90	0.01	FALSE
13	GTEx	Thyroid	MAN2B1	0.09	0.01	lasso	6	0.01	6.0e-02	4.0	5.2	1.7e-07	-0.08	0.10	0.10	FALSE
14	NTR	Blood	IER2	0.03	0.00	bslmm	334	0.01	2.0e-03	-3.8	6.4	1.5e-10	-0.15	0.22	0.03	TRUE
15	ROSMAP	Brain Pre-frontal Cortex	ZNF443	0.05	0.03	lasso	3	0.03	2.8e-04	-5.1	-5.2	1.5e-07	0.00	0.07	0.88	FALSE
16	YFS	Blood	MAN2B1	0.13	0.07	enet	32	0.12	3.1e-38	-4.0	6.2	4.0e-10	-0.09	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	C19orf56	0.02	0.01	blup	23	0.01	1.0e-03	-5.1	6.3	4.0e-10	-0.11	0.01	0.86	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	MAN2B1	0.02	0.01	blup	27	0.01	1.7e-03	-5.5	5.8	7.0e-09	-0.01	0.01	0.97	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZNF709	0.01	0.00	enet	6	0.01	9.1e-03	4.0	5.5	3.1e-08	-0.01	0.01	0.48	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MAN2B1	0.02	0.01	blup	26	0.02	3.1e-03	-5.1	6.3	3.0e-10	-0.08	0.01	0.76	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	WDR83	0.02	0.02	blup	19	0.02	1.6e-03	-4.3	5.4	7.7e-08	-0.03	0.01	0.84	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MAN2B1	0.03	0.01	blup	22	0.03	5.8e-04	-5.1	5.9	4.4e-09	-0.03	0.01	0.91	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TNPO2	0.07	0.05	blup	11	0.07	9.5e-05	4.4	5.2	2.2e-07	-0.03	0.11	0.51	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAN2B1	0.13	0.09	enet	14	0.12	4.4e-13	-4.3	6.2	6.7e-10	-0.05	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF791	0.04	0.00	blup	29	0.02	6.3e-03	4.0	5.5	3.2e-08	-0.05	0.01	0.48	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	MAN2B1	0.03	0.04	blup	21	0.04	3.7e-05	-4.2	5.3	9.2e-08	0.01	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C19orf56	0.42	0.00	lasso	5	0.00	1.1e-01	4.0	6.7	1.6e-11	-0.24	0.00	0.21	FALSE
28	The Cancer Genome Atlas	Soft Tissue Sarcoma	MAN2B1	0.40	0.08	blup	38	0.12	1.2e-07	-4.5	5.7	1.5e-08	-0.13	0.01	0.98	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	MAN2B1	0.03	0.01	blup	33	0.02	1.7e-03	-5.2	5.5	4.5e-08	0.00	0.02	0.90	FALSE