Hub : Genes

ZNF443

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1190	0.0470	4.6e-03	0.078	NA	0.062	NA	0.066	4.2e-05	NA	2.6e-04	NA	1.6e-04
2	GTEx	Brain Frontal Cortex BA9	0.2041	0.0836	9.1e-03	0.001	NA	-0.010	NA	-0.011	2.9e-01	NA	7.5e-01	NA	9.6e-01
3	GTEx	Brain Nucleus accumbens basal ganglia	0.4520	0.1030	6.4e-05	0.072	NA	0.234	NA	0.178	5.5e-03	NA	6.2e-07	NA	1.7e-05
4	GTEx	Breast Mammary Tissue	0.1670	0.0620	8.3e-04	0.032	NA	0.026	NA	0.043	8.5e-03	NA	1.7e-02	NA	3.0e-03
5	GTEx	Breast Mammary Tissue (Male)	0.1265	0.1291	2.2e-01	0.008	NA	-0.013	NA	-0.013	2.0e-01	NA	9.0e-01	NA	8.9e-01
6	GTEx	Breast Mammary Tissue (Female)	0.0529	0.0496	1.8e-01	-0.008	NA	-0.006	NA	-0.001	6.7e-01	NA	5.2e-01	NA	3.4e-01
7	GTEx	Cells Transformed fibroblasts	0.0950	0.0370	2.6e-03	0.051	NA	0.016	NA	0.043	9.8e-05	NA	2.1e-02	NA	3.3e-04
8	GTEx	Esophagus Gastroesophageal Junction	0.1800	0.0630	1.5e-03	0.006	NA	0.040	NA	0.029	1.9e-01	NA	1.4e-02	NA	3.2e-02
9	GTEx	Muscle Skeletal	0.0790	0.0291	3.9e-04	0.015	NA	0.033	NA	0.039	1.0e-02	NA	3.1e-04	NA	1.0e-04
10	GTEx	Nerve Tibial	0.1433	0.0550	1.2e-03	0.069	NA	0.041	NA	0.067	1.2e-05	NA	6.5e-04	NA	1.7e-05
11	GTEx	Testis	0.2480	0.0860	1.4e-04	0.146	NA	0.121	NA	0.136	4.9e-07	NA	5.2e-06	NA	1.2e-06
12	GTEx	Thyroid	0.1660	0.0470	2.2e-06	0.139	NA	0.094	NA	0.127	9.1e-11	NA	1.2e-07	NA	6.6e-10
13	ROSMAP	Brain Pre-frontal Cortex	0.0460	0.0188	9.7e-04	0.034	0.007	0.001	0.008	0.025	2.5e-05	4.0e-02	2.5e-01	0.032	2.8e-04
14	TCGA	Breast Invasive Carcinoma	0.0666	0.0267	5.0e-16	0.089	0.086	0.089	NA	0.089	1.2e-17	3.8e-17	9.2e-18	NA	1.2e-17
15	TCGA	Colon Adenocarcinoma	0.0860	0.0400	1.6e-05	0.106	0.047	0.082	NA	-0.002	1.1e-06	1.0e-03	1.7e-05	NA	4.4e-01
16	TCGA	Prostate Adenocarcinoma	0.0519	0.0259	2.1e-05	0.062	0.043	0.046	NA	0.056	4.4e-07	2.2e-05	1.3e-05	NA	1.4e-06
17	TCGA	Rectum Adenocarcinoma	0.2190	0.1140	4.0e-03	-0.009	0.011	0.017	NA	-0.007	6.0e-01	1.7e-01	1.3e-01	NA	4.9e-01
18	TCGA	Thyroid Carcinoma	0.1280	0.0430	0.0e+00	0.151	0.205	0.211	NA	0.206	1.6e-14	1.2e-19	3.1e-20	NA	9.0e-20

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	0.3	0.5	2.0	0.1	-0.8	-1.4	-0.5	-0.3	0.4	0.3	-0.4	0.4	-1.2	-1.1	-0.3	-1.3	-0.3	1.0	-0.4	0.1	0.1
Bipolar Disorder or Schizophrenia	0.2	0.5	3.1	-0.5	-0.9	-1.7	-0.1	-0.1	-0.4	-0.3	-0.7	0.7	-1.2	-0.6	-0.1	-1.3	-0.2	0.5	-0.1	-0.2	-0.0
Depressed Affect (Nagel 2018)	1.6	3.3	12.9	-2.2	3.6	2.2	-1.1	-1.8	-0.2	-2.2	0.0	-0.8	-0.9	0.9	-1.8	2.9	-1.5	-0.7	-1.8	0.7	-2.6
Depression (Nagel 2018)	1.8	2.7	8.0	-2.5	2.7	1.2	-0.9	-1.6	0.0	-2.4	-0.4	-0.7	-1.2	1.2	-1.5	2.8	-1.2	-0.8	-1.6	0.4	-2.4
Intelligence (Savage-Jansen 2018)	1.7	5.1	21.3	-4.5	-0.0	2.6	0.6	-0.2	-0.9	-4.6	-0.7	-1.8	-0.9	2.9	-0.3	3.3	-0.6	-3.1	-0.4	0.1	-2.8
Neuroticism (Nagel 2018)	1.5	3.5	8.6	-2.2	2.9	2.2	-1.5	-2.0	-0.8	-2.1	-0.4	-1.5	-1.3	0.3	-2.0	2.7	-2.0	-0.4	-1.9	1.3	-2.8
Schizophrenia (2018)	0.1	0.3	1.3	-0.8	-0.5	-1.1	0.2	0.1	-0.7	-0.7	-0.5	0.6	-0.6	0.1	0.1	-0.6	-0.0	-0.1	0.2	-0.3	-0.1
Schizophrenia vs Biploar Disorder	0.8	1.1	2.3	0.7	-1.2	-1.0	1.1	1.2	0.6	0.7	0.1	0.7	1.2	0.4	1.2	-0.9	1.5	-0.5	1.4	-1.4	1.4
Worry (Nagel 2018)	1.2	2.6	5.3	-0.6	1.3	1.0	-2.2	-2.3	-1.0	-0.4	-0.9	-1.7	-1.6	-1.3	-2.3	1.0	-2.3	1.4	-2.2	1.8	-1.8
Alzheimer’s Disease (in mother)	0.7	0.8	2.9	-1.6	0.1	0.3	-0.3	-0.5	1.1	-1.3	-0.6	-1.6	-1.3	0.2	-0.5	1.7	-0.1	-0.2	-0.5	-0.2	-0.8
Alzheimer’s Disease (in father)	1.2	1.3	3.4	0.2	0.6	-0.2	1.4	1.2	0.9	-0.2	1.3	0.8	1.8	1.9	1.2	0.7	1.3	-1.8	1.2	-1.4	0.5
Alzheimer’s Disease (including proxy)	0.5	0.7	2.1	-0.6	0.0	-0.5	0.8	0.8	1.4	-0.7	0.4	0.0	0.2	1.0	0.8	1.0	1.2	-1.0	0.8	-1.4	0.4
Crohns Disease (2017)	0.3	0.6	1.7	-0.3	-0.7	-0.1	0.8	0.7	1.2	-0.1	0.9	1.3	0.1	0.6	0.7	-0.1	0.9	-0.4	0.8	-1.2	0.7
Irritable Bowel Disease (IBD)	0.1	0.2	1.0	0.3	0.4	-0.5	-0.4	-0.5	0.7	0.6	1.0	0.4	-0.4	-0.2	-0.5	0.0	-0.3	0.7	-0.4	0.1	0.1
Ulcerative Colitis (UC)	0.4	0.7	1.6	0.8	0.9	-0.6	-1.0	-1.1	0.5	1.0	0.8	-0.5	-0.6	-0.9	-1.1	0.0	-0.8	1.3	-1.0	0.7	-0.3
Major Depression (MDD)	0.8	1.0	2.2	-0.3	0.9	1.0	-1.2	-1.5	-0.6	-0.3	-0.4	0.1	-1.3	-0.7	-1.5	-0.3	-1.3	0.9	-1.4	1.2	-1.2
Reaction Time	0.3	0.6	2.6	1.6	0.2	-0.4	-0.4	-0.1	1.0	1.6	-0.1	0.5	1.0	-1.1	-0.0	-0.5	0.3	0.9	-0.0	-0.4	0.7
Verbal and Numeric Reasoning (VNR)	3.2	7.8	16.7	-4.1	1.2	3.2	-1.9	-2.7	-2.5	-4.0	-2.2	-2.9	-3.3	0.3	-2.7	2.7	-3.2	-0.4	-2.8	2.3	-4.0
Breast Cancer	1.3	3.0	14.5	1.5	-1.6	-0.7	-1.6	-1.0	0.0	1.8	-3.8	-2.3	-0.9	-2.9	-1.0	-1.9	-0.8	2.5	-1.0	1.0	0.3
Ovarian Cancer	0.6	0.8	2.5	-0.7	0.6	0.7	-0.6	-0.9	-1.3	-0.6	-0.9	-1.6	-0.6	-0.2	-0.9	1.2	-1.1	0.1	-0.9	1.2	-1.0
Prostate Cancer	0.3	0.4	1.3	-0.7	-0.2	-0.6	-0.3	-0.4	-0.6	-0.6	1.1	-0.7	-1.0	0.4	-0.4	0.8	-0.6	-0.0	-0.5	0.5	-0.6
Age at First Birth	0.4	0.5	4.1	-0.0	-2.0	-1.1	-0.4	-0.2	0.1	0.1	0.8	-0.5	-1.0	-0.7	-0.2	-1.0	-0.1	0.6	-0.2	-0.2	0.1
Bipolar Disorder (2011)	0.9	0.8	5.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.8	2.4	-1.8	1.5	-0.8
Body Mass Index (BMI) (2010)	0.1	0.2	0.7	-0.2	0.6	0.1	0.5	0.4	-0.8	-0.3	-0.2	0.5	0.3	0.5	0.4	0.5	0.1	-0.5	0.4	0.2	0.1
Coronary Artery Disease (CAD)	0.4	0.4	1.0	-0.2	0.4	-0.2	0.8	0.8	0.8	-0.2	0.0	0.8	1.0	0.5	0.8	0.2	0.8	-0.8	0.8	-0.9	0.4
Crohns Disease (2012)	0.8	1.3	3.3	0.3	-1.8	-0.6	1.1	1.4	0.8	0.4	0.4	1.6	0.3	0.5	1.4	-1.1	1.5	-0.2	1.5	-1.7	1.5
Mean Putamen Volume	3.1	3.5	8.8	1.5	-2.8	-3.0	1.9	2.2	2.0	1.4	1.3	-0.3	1.9	0.5	2.1	-1.2	2.3	-0.7	2.1	-1.6	2.4
Fasting Glucose	0.6	0.7	2.5	-0.6	1.1	0.9	-0.4	1.2	0.7	-0.7	0.3	-0.1	-0.1	0.2	1.2	1.6	-0.6	-1.2	-0.4	-0.5	-1.2
HbA1C	2.5	2.8	6.9	-0.2	-1.7	-0.1	-2.3	-1.4	-0.1	-0.4	-2.6	-2.3	-2.5	-1.7	-1.4	-0.3	-2.1	1.7	-2.0	1.2	-1.8
HDL Cholesterol	0.6	1.0	2.5	1.1	0.7	-0.5	-1.3	-1.2	0.2	1.2	-0.5	0.0	-0.5	-1.6	-1.2	-0.9	-1.0	1.6	-1.2	0.7	-0.3
LDL Cholesterol	0.2	0.3	1.0	0.3	-0.0	-0.6	-0.1	-0.2	-0.1	0.3	-0.6	0.4	-0.8	-1.0	-0.1	-0.8	-0.1	0.9	-0.1	0.4	0.4
Lupus	1.3	2.0	6.1	-1.9	2.5	1.7	-0.5	-1.2	-0.8	-1.9	0.6	0.4	-0.6	1.0	-1.2	2.3	-1.3	-0.9	-1.2	0.9	-2.0
Neuroticism (2016)	3.7	5.4	12.7	-1.5	1.0	1.3	-3.0	-3.4	-0.3	-1.4	-1.8	-3.2	-2.5	-0.7	-3.4	1.2	-2.9	1.1	-3.6	1.6	-3.3
Primary Biliary Cirrhosis	0.2	0.4	2.3	-0.3	-0.5	-0.1	0.6	0.4	1.5	-0.2	-0.1	0.2	0.4	0.7	0.4	0.2	0.8	-0.6	0.4	-1.0	0.2
Rheumatoid Arthritis	0.7	1.0	3.1	-0.9	1.8	0.7	-0.8	-1.1	0.3	-1.0	-0.6	-1.0	-0.6	0.6	-1.1	1.3	-0.9	-0.2	-1.1	0.2	-1.5
Schizophrenia (2014)	0.3	0.6	2.4	-0.9	-0.4	-1.2	-0.6	-0.6	-1.0	-0.7	-0.8	0.1	-1.5	-0.8	-0.6	-1.0	-0.8	0.8	-0.6	0.3	-0.5
Triglycerides	0.7	1.2	5.1	-0.9	-1.2	-0.8	-1.1	-0.9	-0.4	-0.7	-0.1	-2.0	-2.3	-0.9	-0.9	-0.9	-1.1	1.1	-0.9	1.1	-0.6
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.7	-1.1	-0.1	0.6	-1.1	-1.5	1.3	-1.0	-1.6	-1.9	-1.2	-0.5	-1.5	0.9	-1.0	0.5	-1.5	-0.0	-1.6
Ulcerative Colitis	0.3	0.5	1.7	0.9	-0.2	-0.8	-0.5	-0.1	-0.4	1.0	-0.2	0.3	-0.6	-1.1	-0.1	-1.2	-0.2	1.3	-0.0	0.8	0.7
Blood Eosinophil Count	0.1	0.8	8.2	0.3	0.0	0.7	0.3	0.5	-1.6	0.4	-2.9	0.8	0.2	-0.6	0.5	-0.4	-0.1	0.2	0.6	0.7	0.8
Blood Platelet Count	0.4	4.8	15.8	-2.2	4.0	2.5	-0.9	-1.8	1.3	-2.4	3.6	0.5	-0.6	1.0	-1.8	3.5	-1.2	-1.4	-1.8	-1.3	-3.0
Blood Red Count	3.4	32.8	380.2	1.1	-4.9	4.4	-3.2	-1.8	-4.2	1.9	-19.5	-2.9	-4.0	-4.9	-1.7	-4.8	-2.7	5.4	-1.7	4.1	0.7
Blood White Count	0.3	2.1	5.6	-0.3	0.6	-0.1	-1.9	-1.8	-1.8	-0.2	-0.3	-0.7	-1.8	-1.6	-1.7	-0.5	-2.0	1.6	-1.7	2.4	-1.3
Heel T-Score	0.9	7.5	27.6	3.4	-4.3	-3.4	-1.1	0.3	-2.0	3.7	-2.1	-2.0	-1.3	-3.3	0.2	-5.2	-0.3	3.7	0.4	1.9	2.6
BMI	0.4	2.1	17.4	-1.2	2.4	2.1	-0.5	-0.6	-0.6	-1.2	-4.2	1.4	-0.1	0.3	-0.6	0.5	-0.7	-0.5	-0.7	0.6	-1.2
Height	0.5	9.9	43.3	-1.4	5.8	1.6	-1.4	-2.4	5.9	-1.7	6.6	-0.3	-0.1	1.4	-2.5	4.1	-0.8	-1.2	-2.6	-2.5	-3.4
Waist Hip Ratio (WHR)	0.8	3.4	7.5	-2.2	1.6	2.2	-1.6	-2.2	1.4	-2.1	1.7	-1.6	-2.1	0.7	-2.2	2.5	-1.6	-0.0	-2.1	-0.2	-2.7
Systolic Blood Pressure	2.0	10.2	31.1	-2.9	1.5	1.2	4.0	2.8	2.3	-3.2	2.6	3.3	2.6	5.6	2.8	3.0	3.1	-5.3	2.8	-3.8	0.2
Smoking Status	0.6	1.5	6.0	-1.0	2.0	2.5	-0.6	-1.1	0.4	-1.0	1.7	-0.1	-0.2	0.6	-1.1	2.0	-0.8	-0.4	-1.1	0.2	-1.5
Allergy or Eczema	0.8	2.2	5.4	-1.2	2.3	2.2	-1.1	-1.6	-0.4	-1.2	-2.0	-1.2	-1.1	-0.1	-1.6	1.9	-1.5	0.3	-1.5	1.0	-1.8
Cardiovascular Disease	2.0	6.7	21.5	-4.0	1.2	0.9	2.5	1.5	2.0	-4.1	0.5	1.7	1.0	4.6	1.5	3.1	2.0	-4.4	1.4	-3.1	-1.1
Hypothyroidism (self reported)	0.4	0.8	2.5	-1.5	0.4	1.2	0.3	-0.2	-0.6	-1.4	1.2	-0.4	-0.3	1.1	-0.2	1.6	-0.3	-1.1	-0.2	0.7	-0.9
Respiratory disease	1.0	2.2	7.9	2.7	-0.8	-1.0	-0.2	0.7	0.4	2.8	-1.3	0.4	0.8	-1.9	0.7	-2.5	0.5	1.8	0.8	-0.2	2.1
Type 2 Diabetes (T2D) (2018)	0.6	1.0	8.2	-0.7	-0.0	0.8	-0.1	-0.3	2.9	-0.7	-2.4	0.3	0.1	0.2	-0.3	0.5	0.5	-0.1	-0.3	-1.4	-0.5
Lung FEV1/FVC ratio	0.3	1.4	5.1	-2.1	0.0	1.1	1.1	0.3	-0.9	-2.3	0.1	0.3	-0.2	2.1	0.3	1.8	0.2	-1.9	0.3	-0.3	-1.0
Lung FVC	0.3	1.7	6.2	-1.9	0.4	1.9	-0.0	-0.6	-2.5	-1.8	0.1	-1.1	-0.8	1.2	-0.6	1.7	-1.2	-0.9	-0.7	1.2	-1.4
Neuroticism	1.5	3.7	10.1	-1.9	3.0	2.0	-1.6	-2.2	-0.1	-1.9	-0.6	-2.2	-0.9	0.4	-2.3	3.2	-1.8	-0.3	-2.2	1.1	-2.9
Chronotype (morning person)	0.3	0.7	1.5	-0.7	0.4	-0.1	-0.7	-1.1	-0.9	-0.6	0.9	-0.8	-0.8	-0.1	-1.2	1.0	-1.2	0.0	-1.1	1.1	-1.2
Hair Pigment	0.0	0.5	1.9	-0.8	0.9	0.6	0.7	0.8	-0.4	-1.0	1.4	-0.1	0.4	0.5	0.8	0.9	0.5	-0.3	0.8	0.3	-0.1
Tanning	0.2	2.1	7.6	0.8	-0.4	-0.5	1.9	1.6	1.0	0.6	2.8	0.8	1.9	1.6	1.5	0.2	1.7	-1.5	1.6	-1.6	1.2
Hand grip strength (left)	0.6	1.6	4.8	1.8	-0.5	-2.2	-0.4	0.2	1.6	1.8	1.9	-0.3	-0.4	-1.2	0.1	-2.1	0.4	1.4	0.1	-0.7	1.1
Number of treatments/medications taken	1.0	1.8	7.3	-2.1	0.4	0.1	0.5	-0.3	0.4	-2.3	1.0	-0.9	0.4	2.1	-0.3	2.7	-0.0	-2.2	-0.3	-0.6	-1.6
Average weekly spirits intake	0.3	0.3	1.5	-0.1	1.2	0.8	0.0	0.2	-1.1	-0.1	0.8	0.7	-0.4	0.1	0.2	-0.1	-0.2	-0.1	0.2	1.0	0.1
Sensitivity / hurt feelings	0.4	0.7	3.2	-0.9	1.6	0.9	-0.3	-0.7	0.6	-0.9	0.2	-0.6	0.2	0.9	-0.7	1.8	-0.2	-0.6	-0.6	-0.2	-1.2
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.5	-0.5	0.7	-0.0	-0.0	0.0	-0.6	-0.4	-0.7	-0.1	-0.4	0.3	0.1	0.3	-0.0	-0.1	0.1	0.5	-0.0
Hearing difficulty/problems: Yes	0.8	1.2	7.2	0.9	0.4	1.0	-0.4	0.0	-2.7	1.0	-1.3	-0.0	0.1	-0.9	-0.0	-1.5	-0.7	0.7	0.1	2.4	0.6
Relative age of first facial hair	0.5	1.0	3.1	-1.3	1.7	1.6	-0.8	-1.0	-0.5	-1.2	0.9	-0.5	-1.0	0.2	-1.0	1.3	-0.8	-0.2	-1.0	-0.1	-1.3
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.6	-0.8	0.3	-0.0	-0.7	-1.0	-0.0	-0.8	0.3	-0.6	-1.2	-0.2	-1.0	1.3	-0.9	0.1	-1.0	0.7	-1.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.1	-0.2	-0.1	0.9	0.5	0.4	0.4	-0.3	-0.5	0.3	0.5	1.0	0.4	0.5	0.5	-0.7	0.4	-0.5	0.1
Ever had hysterectomy (womb removed)	0.7	0.7	3.0	1.0	1.1	-0.6	0.4	0.5	1.7	0.8	-1.3	0.9	1.3	0.2	0.5	-0.0	0.9	-0.2	0.5	-1.1	0.6
Systolic blood pressure, automated reading	1.3	3.9	10.4	-1.4	1.7	1.5	2.5	1.8	0.5	-1.6	1.6	2.3	1.8	3.2	1.9	1.8	1.9	-3.2	1.8	-2.0	0.3
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.9	-0.5	1.0	0.2	-0.2	-0.2	1.0	-0.3	-0.4	1.4	-0.1	0.1	-0.2	0.1	0.1	-0.0	-0.2	-0.5	-0.2
Angina	0.1	0.1	0.3	-0.3	0.1	-0.1	-0.1	0.0	0.5	-0.1	-0.5	0.5	-0.4	0.2	0.1	-0.3	0.1	0.0	-0.0	-0.3	0.1
Medication for hormone replacement therapy	0.4	0.5	2.5	0.5	-0.6	-1.6	-0.4	-0.3	-1.2	0.5	-0.4	-0.1	-0.7	-0.7	-0.3	-0.8	-0.5	0.6	-0.3	1.0	0.1
Vitamin and mineral supplements	0.1	0.1	0.4	-0.1	-0.4	0.6	-0.3	-0.0	0.5	-0.1	0.2	-0.4	-0.5	-0.4	0.0	-0.3	0.0	0.3	-0.0	-0.5	0.1
Supplements: Zinc	0.5	0.6	2.4	0.7	-0.2	-1.2	-0.5	-0.6	-0.8	0.7	0.4	-1.5	-0.5	-0.6	-0.6	0.2	-0.6	0.7	-0.5	1.5	-0.1
Medication: Co-codamol	0.4	0.4	2.1	-0.7	1.0	1.0	0.3	-0.1	-0.4	-0.8	0.0	-0.2	0.4	1.0	-0.1	1.5	-0.2	-0.9	-0.1	-0.1	-0.7
Medication: Metformin	1.1	1.6	11.6	-1.0	0.9	0.5	-1.3	-1.4	0.8	-0.7	-3.4	-0.6	-1.2	-0.7	-1.4	0.1	-1.1	0.8	-1.4	0.3	-1.3
Diabetes (father)	0.3	0.4	1.5	0.6	1.1	-0.3	-0.1	-0.0	1.1	0.5	-0.5	1.2	0.3	-0.1	-0.0	-0.9	0.3	0.2	0.0	-0.5	0.2
Diabetes (mother)	1.2	1.5	7.2	0.7	-0.1	0.5	0.9	1.1	2.7	0.7	-1.9	0.8	1.5	0.5	1.1	-0.4	1.7	-0.5	1.1	-1.9	1.2
Severe depression (siblings)	0.6	0.7	1.7	-1.3	0.6	1.3	-0.3	-0.6	-0.7	-1.2	-0.5	-1.1	-0.6	0.6	-0.6	1.1	-0.8	-0.4	-0.6	0.6	-1.0
Pack years adult smoking proportion	0.2	0.3	1.9	0.6	0.6	0.3	-0.5	-0.5	1.4	0.7	0.3	0.5	-0.3	-0.5	-0.5	-0.0	-0.1	0.8	-0.5	-0.3	0.0
Impedance of leg (right)	0.2	0.8	5.0	-0.5	0.1	-0.5	-0.4	-0.5	1.6	-0.4	2.2	-1.1	-1.0	0.2	-0.6	1.0	0.1	0.2	-0.4	-1.5	-0.5
Leg fat-free mass (left)	0.3	1.8	13.6	-0.1	3.7	1.4	-1.4	-1.5	1.2	-0.2	-1.1	1.0	-0.1	-0.5	-1.5	0.3	-1.2	0.4	-1.6	0.6	-1.5
Trunk fat percentage	0.2	1.0	8.5	-0.2	2.9	1.5	-0.6	-0.5	-0.4	-0.1	-0.9	2.0	-0.1	-0.1	-0.4	-0.1	-0.6	0.0	-0.6	0.3	-0.6
Hand grip strength (right)	0.4	1.2	4.7	1.1	-0.1	-1.0	-1.2	-0.6	0.5	1.3	0.0	-0.6	-1.6	-1.7	-0.6	-2.2	-0.7	2.0	-0.7	0.3	0.4
Townsend deprivation index at recruitment	0.8	1.1	4.2	2.0	-1.0	-0.7	0.2	0.7	0.4	2.0	-0.3	0.5	1.2	-1.0	0.8	-1.5	0.7	1.0	0.7	-0.3	1.6
Current tobacco smoking	2.1	3.4	6.5	-0.8	2.0	2.5	-2.2	-2.5	-0.4	-0.7	-1.4	-1.0	-1.9	-1.0	-2.5	1.4	-2.4	1.4	-2.5	1.9	-2.2
Average weekly fortified wine intake	3.4	3.9	8.2	-0.2	1.6	1.3	-2.6	-2.9	-0.5	-0.2	-1.1	-2.2	-2.4	-1.9	-2.9	0.5	-2.7	2.0	-2.8	1.7	-2.3
Maternal smoking around birth	0.7	1.1	3.6	-0.9	0.8	0.6	0.4	-0.2	1.9	-1.0	1.3	-0.2	0.7	1.5	-0.2	1.8	0.3	-1.4	-0.2	-1.3	-0.9
Fed-up feelings	2.4	4.3	12.6	-2.5	3.5	2.8	-1.3	-2.2	0.9	-2.6	-0.0	-1.1	-0.8	1.4	-2.2	3.1	-1.6	-0.9	-2.3	0.2	-3.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	4.7	-1.6	1.7	0.4	-0.9	-1.4	-0.1	-1.6	-0.5	-1.1	-0.9	0.7	-1.4	2.2	-1.1	-0.4	-1.4	0.6	-1.9
Relative age voice broke	1.5	2.3	8.4	-0.8	1.0	0.9	1.4	1.3	1.5	-0.9	2.9	1.0	0.9	2.0	1.3	1.6	1.5	-1.8	1.1	-2.4	0.4
Taking other prescription medications	0.9	1.4	3.3	-1.3	0.2	0.3	-1.1	-1.5	-0.6	-1.3	-0.1	-1.4	-1.3	-0.1	-1.5	1.1	-1.6	0.0	-1.6	1.4	-1.8
Age when periods started (menarche)	0.4	1.1	6.1	-0.2	1.4	1.1	-0.4	-0.8	2.1	-0.3	2.5	0.1	0.2	-0.4	-0.8	1.3	-0.2	-0.1	-0.8	-1.0	-0.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.2	0.4	0.6	-1.0	0.1	0.3	1.5	0.4	-0.3	1.2	0.6	-0.0	0.3	-0.7	0.7	-0.0	0.3	-0.8	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.9	1.9	8.3	1.1	-2.0	-1.2	-0.6	0.1	-1.6	1.3	-2.9	-0.9	-0.7	-1.7	0.1	-2.3	-0.3	1.8	0.2	1.2	1.1
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	4.5	0.1	-2.1	-1.6	1.4	1.3	0.0	0.1	1.1	0.2	0.3	0.8	1.3	-0.8	1.2	-0.6	1.4	-1.0	1.2
Qualifications: CSEs or equivalent	0.5	0.7	2.7	-0.3	1.6	1.0	0.7	0.4	-0.8	-0.5	0.0	1.1	1.3	1.4	0.4	0.8	0.3	-1.2	0.4	-0.1	-0.2
Serious illness, injury or assault to yourself	0.8	0.9	2.4	0.2	0.2	-0.7	1.4	1.3	-0.3	0.1	0.2	1.3	1.6	1.2	1.3	0.7	1.0	-1.2	1.3	0.1	0.9
High blood pressure	2.3	6.5	22.4	-3.9	0.6	0.6	2.6	1.5	0.8	-4.1	1.2	1.1	1.3	4.7	1.5	3.4	1.8	-4.6	1.5	-2.5	-1.1
Hayfever, allergic rhinitis or eczema	0.4	1.0	2.2	-0.3	1.3	1.2	-0.9	-1.0	-1.3	-0.3	-1.4	-1.0	-0.8	-0.5	-1.0	0.5	-1.2	0.5	-0.9	1.5	-0.9
Multivitamins +/- minerals	0.6	0.8	2.0	-0.2	0.1	-0.8	1.4	1.1	-0.9	-0.2	0.8	1.4	0.9	1.2	1.1	0.5	0.8	-1.3	1.1	0.1	0.6
Stomach or abdominal pain in last month	3.1	3.9	10.2	2.5	-0.4	-0.1	-2.0	-1.0	-2.8	2.6	-2.5	-1.2	-0.6	-3.2	-1.0	-1.8	-1.6	3.2	-1.0	2.7	0.7
Supplements: Glucosamine	0.4	0.5	2.9	0.6	0.1	-1.2	-0.4	-0.3	-1.7	0.5	-0.1	-0.8	-0.1	-0.6	-0.4	0.1	-0.7	0.4	-0.4	1.2	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.7	0.0	0.9	1.1	-0.1	-0.1	-1.3	-0.0	0.7	0.3	0.0	0.1	-0.1	0.2	-0.4	-0.0	-0.1	1.0	-0.1
Medication: Atenolol	1.3	1.7	4.8	-2.2	2.0	1.3	-0.1	-0.7	-0.3	-2.1	-0.7	-0.1	-0.6	1.7	-0.8	2.1	-0.5	-1.4	-0.7	0.1	-1.7
Medication: Levothyroxine sodium	1.2	2.0	6.7	-2.3	0.1	1.5	0.4	-0.3	0.1	-2.4	1.8	-1.3	-0.6	2.0	-0.4	2.6	-0.4	-1.7	-0.5	0.0	-1.7
Sitting height	0.3	2.1	18.1	1.1	2.1	0.0	0.4	0.2	4.3	0.8	0.9	1.0	1.5	0.4	0.2	0.5	1.2	-0.5	0.1	-2.6	0.2
Chronic bronchitis/emphysema (father)	0.5	0.6	2.3	-1.5	-1.0	1.2	0.6	0.5	0.0	-1.2	0.8	0.0	-0.4	1.1	0.5	0.7	0.4	-0.8	0.5	0.0	0.0
High blood pressure (mother)	3.2	4.4	13.2	-1.4	-0.5	0.2	2.9	2.3	1.3	-1.7	1.0	0.8	2.1	3.6	2.3	2.0	2.7	-3.4	2.4	-2.4	0.7
Body mass index (BMI)	0.3	1.5	9.3	-0.5	2.4	1.4	-0.5	-0.4	-1.5	-0.5	-3.1	1.8	-0.2	-0.0	-0.3	-0.7	-0.7	0.0	-0.4	1.3	-0.5
Impedance of leg (left)	0.2	1.0	6.5	-0.3	-0.9	-0.7	0.5	0.3	1.6	-0.2	2.5	-0.8	-0.4	0.7	0.3	1.0	0.8	-0.3	0.4	-1.9	0.2
Leg predicted mass (left)	0.4	1.9	13.3	0.0	3.6	1.3	-1.5	-1.6	1.2	-0.1	-1.1	0.8	-0.2	-0.6	-1.6	0.2	-1.2	0.5	-1.7	0.7	-1.5
Trunk fat mass	0.3	1.5	12.8	-0.5	3.6	1.8	-0.9	-0.9	0.2	-0.5	-1.1	1.7	-0.1	0.0	-0.9	0.3	-0.8	-0.1	-1.0	0.2	-1.1
Waist circumference	0.7	2.7	13.3	-1.9	3.6	2.9	-1.0	-1.4	-0.5	-1.9	-1.3	1.1	-0.9	0.7	-1.4	1.2	-1.3	-0.6	-1.4	0.8	-2.1
Number of incorrect matches in round	3.3	5.5	15.1	2.8	-3.6	-3.3	0.6	1.4	3.9	2.9	-0.9	-0.7	0.9	-1.4	1.4	-3.4	2.2	1.4	1.5	-2.6	2.8
Past tobacco smoking	1.0	1.8	9.8	-0.1	-1.2	-1.1	-1.1	-0.8	-1.1	0.1	-3.1	-1.1	-2.1	-1.6	-0.8	-1.0	-1.1	1.7	-0.8	1.2	-0.2
Alcohol usually taken with meals	0.8	1.2	2.9	-0.2	0.3	0.7	-1.3	-1.3	-1.0	-0.1	-1.6	-0.1	-1.6	-1.7	-1.2	-0.3	-1.3	1.4	-1.2	1.5	-0.8
Nervous feelings	1.3	2.4	4.9	-1.5	1.2	1.4	-1.8	-2.1	-0.5	-1.4	0.3	-1.2	-2.0	-0.7	-2.1	1.6	-2.0	0.8	-2.0	0.9	-2.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.3	-0.6	1.1	0.6	-0.7	-0.8	-0.4	-0.5	-0.6	-0.6	-0.9	0.0	-0.7	0.8	-0.8	0.4	-0.7	0.6	-0.7
Hearing difficulty/problems with background noise	1.2	2.0	5.4	1.7	-1.4	-0.5	1.2	1.7	-0.5	1.7	-0.5	1.4	1.4	-0.6	1.7	-2.3	1.3	0.3	1.8	0.1	2.3
Hair/balding pattern: Pattern 2	0.9	1.2	6.9	1.1	-2.6	-1.3	0.4	0.6	1.4	1.2	0.3	-0.3	0.1	-0.9	0.6	-1.5	0.8	0.7	0.6	-1.1	1.2
Had menopause	0.4	0.5	1.3	-0.5	-0.1	1.0	0.9	0.7	0.1	-0.5	0.1	0.6	0.7	0.9	0.7	0.8	0.7	-1.2	0.7	-0.7	0.2
Had other major operations	0.4	0.4	2.8	0.5	-0.2	-0.1	0.3	0.6	0.3	0.5	1.2	1.7	0.5	0.1	0.7	-0.9	0.4	0.1	0.5	-0.1	0.7
Forced vital capacity (FVC)	0.5	2.0	4.6	-1.1	1.7	1.4	-1.5	-1.9	-0.2	-1.2	1.3	-1.3	-1.1	0.2	-1.9	1.6	-1.8	0.3	-1.9	0.8	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	8.8	2.0	-1.5	-1.7	-1.1	-0.2	-1.8	2.2	-2.6	-0.6	-0.7	-2.4	-0.2	-3.0	-0.7	2.6	-0.2	1.6	1.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.7	0.4	0.8	0.4	-0.5	-0.5	0.9	0.4	-0.5	-0.3	0.1	-0.1	-0.5	0.4	-0.2	0.5	-0.5	0.1	-0.3
Qualifications: None of the above	0.3	0.7	2.1	1.4	0.8	0.5	0.2	0.6	0.8	1.5	1.1	0.9	1.1	-0.3	0.6	-0.7	0.5	0.3	0.4	-0.5	1.0
Financial difficulties in last 2 years	1.1	1.4	5.3	0.6	-0.7	0.3	-0.9	-0.7	-2.3	0.7	-2.3	-0.9	-0.8	-1.5	-0.7	-0.7	-1.2	1.5	-0.6	2.0	0.0
Mouth/teeth dental problems	0.6	0.9	4.6	-0.6	-0.8	-0.2	-0.9	-1.0	-0.6	-0.6	-0.4	-2.1	-1.5	-0.7	-1.1	0.4	-1.0	0.7	-1.0	0.6	-1.0
Heart attack	2.7	3.4	10.1	-2.3	-1.1	0.0	2.4	1.8	0.9	-2.4	1.2	1.3	0.9	3.2	1.7	1.5	1.9	-3.1	1.8	-1.9	0.2
Allergy	0.1	0.3	1.1	-0.6	-1.0	-0.5	0.5	0.2	0.6	-0.6	1.0	0.6	-0.1	0.6	0.2	0.2	0.4	-0.5	0.2	-0.6	-0.1
Pain all over the body in last month	0.2	0.3	0.7	0.5	0.3	-0.8	0.2	0.6	-0.5	0.5	0.4	0.2	0.5	-0.1	0.6	-0.8	0.3	-0.0	0.6	0.6	0.8
Diabetes (self-reported)	0.7	1.1	6.4	-0.9	1.2	1.1	-0.1	-0.6	2.3	-0.8	-2.5	0.4	0.3	0.6	-0.5	1.0	0.2	-0.5	-0.5	-1.0	-0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.3	-0.3	1.2	0.3	-0.9	-1.1	0.7	-0.3	-0.3	-0.1	-0.4	0.2	-1.1	0.4	-0.7	0.2	-1.1	0.5	-1.1
Medication: Ramipril	1.0	1.3	3.5	-1.9	0.7	0.6	0.9	0.3	0.6	-1.9	-0.9	1.5	0.5	1.8	0.3	1.7	0.6	-1.8	0.3	-1.1	-0.7
Medication: Simvastatin	0.4	0.6	2.5	-1.6	0.1	0.4	-0.1	-0.4	-0.1	-1.4	-1.3	0.4	-1.1	0.7	-0.3	0.3	-0.4	-0.5	-0.5	0.2	-0.9
Fluid intelligence score	1.3	2.7	5.9	-2.4	1.3	1.8	-1.1	-1.5	-1.4	-2.4	-1.2	-1.9	-1.9	0.4	-1.5	1.7	-1.8	-0.4	-1.6	1.1	-2.4
Illnesses of siblings	0.8	1.2	3.2	1.1	-1.1	-0.2	-1.3	-1.1	0.0	1.1	0.4	-0.9	-0.9	-1.8	-1.1	-1.6	-1.0	1.8	-1.0	0.5	-0.2
Neuroticism score	1.7	3.5	6.5	-1.3	2.5	2.2	-2.2	-2.5	-0.3	-1.3	-0.9	-2.2	-1.5	-0.6	-2.5	1.9	-2.2	0.8	-2.5	1.3	-2.6
Weight	0.4	2.2	17.4	-0.7	4.2	1.9	-1.2	-1.4	0.9	-0.7	-1.5	1.3	-0.3	0.1	-1.4	0.6	-1.1	-0.0	-1.5	0.3	-1.7
Impedance of arm (right)	0.2	0.9	13.1	0.7	-0.3	-0.7	-0.1	-0.1	0.1	0.6	3.6	-0.6	0.3	-0.3	-0.1	0.8	-0.0	0.3	-0.1	-0.5	0.1
Arm fat percentage (right)	0.2	0.8	3.9	-0.5	2.0	1.0	-0.2	-0.1	-1.5	-0.4	-1.7	1.8	0.1	0.1	-0.1	-0.5	-0.4	-0.2	-0.1	0.8	-0.3
Trunk fat-free mass	0.4	2.3	13.9	-1.0	3.7	1.4	-1.3	-1.6	2.6	-1.1	-0.6	0.3	-0.6	0.2	-1.7	1.0	-0.9	-0.2	-1.7	-0.2	-2.1
Hip circumference	0.5	2.4	17.4	-1.4	4.2	2.4	-0.1	-0.4	-0.1	-1.5	-1.7	2.3	0.4	1.3	-0.4	0.8	-0.3	-1.3	-0.5	-0.1	-1.4
Time employed in main current job	0.4	0.5	2.6	-1.3	-1.6	-0.7	0.2	0.0	0.7	-1.1	0.4	-0.6	-0.7	0.5	-0.0	-0.4	0.2	-0.5	0.1	-0.2	-0.3
Alcohol intake versus 10 years previously	0.6	0.9	4.5	-0.9	2.1	0.8	-0.5	-0.9	0.6	-1.0	0.1	-0.4	0.4	0.5	-0.9	1.6	-0.7	-0.6	-1.0	0.1	-1.4
Father’s age at death	0.7	0.9	2.2	-0.2	0.9	-0.0	-1.2	-1.1	0.0	-0.1	-1.2	-1.2	-1.5	-1.0	-1.1	0.3	-1.1	1.1	-1.1	0.8	-0.7
Worrier / anxious feelings	1.3	2.5	5.4	0.2	0.6	0.4	-2.3	-2.2	-0.6	0.3	0.0	-2.2	-1.5	-1.8	-2.2	-0.2	-2.1	1.8	-2.1	1.7	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	3.8	-0.6	0.2	0.3	1.5	1.4	-0.3	-0.5	1.4	2.0	1.1	1.7	1.4	0.4	1.3	-1.6	1.4	-0.6	0.8
Falls in the last year	0.4	0.5	2.4	0.7	1.3	0.7	0.5	0.7	-0.5	0.6	-0.4	1.0	1.6	0.3	0.7	0.1	0.3	-0.5	0.6	0.4	0.6
Hair/balding pattern: Pattern 3	0.1	0.2	2.9	-0.0	0.0	0.7	-0.1	0.0	0.5	-0.1	-1.7	-0.1	-0.1	-0.2	0.0	0.1	0.1	0.2	0.0	0.3	-0.0
Number of live births	0.1	0.1	1.1	-0.3	0.1	0.1	0.3	0.2	-0.3	-0.3	1.1	0.1	0.4	0.5	0.2	0.3	0.2	-0.5	0.2	-0.2	-0.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	4.1	-1.2	1.7	1.5	-1.2	-1.7	-0.8	-1.2	0.9	-0.9	-1.2	0.2	-1.7	1.6	-1.8	0.2	-1.7	1.1	-2.0
Pulse rate	0.8	1.4	6.2	-1.9	0.0	2.5	-0.2	-0.7	-0.6	-1.9	1.0	-0.6	-1.1	0.7	-0.7	1.7	-0.7	-0.6	-0.8	0.3	-1.4
Happiness	2.2	2.6	6.5	-2.4	1.6	1.7	-1.4	-1.8	-0.7	-2.3	-0.6	-0.7	-1.7	0.5	-1.8	1.7	-1.8	-0.1	-1.9	1.3	-2.5
Noisy workplace	0.5	0.6	2.7	0.9	-0.3	0.1	0.8	1.0	-0.0	0.8	0.4	0.4	1.6	0.6	0.9	-0.4	0.8	-0.5	0.9	-0.1	0.9
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.0	-1.4	-0.6	0.5	-0.5	-0.6	-0.4	-1.4	-1.7	-1.6	-1.7	-0.2	-0.6	0.4	-0.7	-0.0	-0.6	-0.0	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.2	-1.5	-0.2	0.8	-0.2	-0.2	-0.9	-1.3	-1.0	0.2	-0.8	0.3	-0.2	0.2	-0.3	-0.2	-0.1	0.3	-0.6
Mouth/teeth dental problems: Dentures	0.9	1.5	9.1	-0.1	2.3	1.0	0.8	0.6	1.5	-0.1	0.4	3.0	1.2	1.3	0.7	0.3	0.9	-1.1	0.5	-1.2	0.2
Asthma	0.4	0.8	2.6	1.6	-0.7	-0.4	-0.3	0.3	0.1	1.6	-0.6	-0.2	0.3	-1.3	0.3	-1.5	0.2	1.3	0.4	-0.1	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.1	0.2	-0.1	-0.1	-1.0	-0.6	-1.3	0.3	-1.3	-1.4	-0.6	-0.9	-0.6	-0.7	-0.9	0.9	-0.7	1.1	-0.2
Medication: Cholesterol lowering	0.5	0.8	2.8	-0.7	-0.9	-1.1	0.8	0.6	1.7	-0.6	1.3	0.6	0.1	1.1	0.6	0.2	0.8	-1.0	0.5	-1.1	0.2
Depression (self-reported)	0.4	0.5	3.1	0.8	0.0	-0.1	0.7	0.6	0.5	0.7	0.4	0.4	1.8	0.5	0.6	0.8	0.8	-0.6	0.7	-0.5	0.7
Medication: Lansoprazole	0.2	0.2	1.0	0.2	1.0	-0.4	-0.2	-0.1	0.6	0.2	1.0	0.8	0.4	0.1	-0.1	-0.1	0.1	0.0	-0.1	-0.3	0.0
Prospective memory result	0.2	0.2	1.0	0.0	0.4	-0.7	-0.2	-0.4	1.0	0.1	0.9	0.2	0.2	0.4	-0.4	0.3	-0.1	-0.1	-0.5	-0.4	-0.4
Lung cancer (father)	0.3	0.3	0.9	0.9	0.2	0.1	-0.1	-0.0	1.0	0.9	-0.4	1.0	0.4	-0.4	-0.0	-0.9	0.2	0.4	-0.0	-0.1	0.4
Illnesses of mother	2.8	3.5	9.1	1.6	0.8	-0.8	-2.6	-2.2	-1.1	1.7	-0.7	-0.6	-1.5	-3.0	-2.2	-1.7	-2.4	3.0	-2.3	1.8	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	3.3	-1.2	1.7	1.6	-1.0	-1.5	-1.1	-1.2	0.4	-0.3	-1.0	0.2	-1.5	1.5	-1.7	0.2	-1.6	1.1	-1.8
Pulse wave Arterial Stiffness index	0.7	0.8	1.8	1.0	-0.1	0.1	0.8	1.1	0.5	0.8	0.6	1.3	1.2	0.2	1.1	-1.2	1.1	-0.3	1.1	-0.9	1.2
Impedance of arm (left)	0.2	1.1	12.2	1.3	-0.7	-1.3	-0.2	-0.1	0.3	1.3	3.5	-0.6	0.1	-0.8	-0.1	0.1	0.0	0.8	-0.0	-0.5	0.5
Arm fat mass (right)	0.3	1.3	8.8	-0.3	3.0	1.3	-0.8	-0.7	-0.9	-0.3	-2.0	1.8	-0.0	-0.2	-0.6	-0.4	-0.8	0.1	-0.7	0.9	-0.7
Trunk predicted mass	0.4	2.2	13.4	-1.0	3.7	1.4	-1.2	-1.6	2.4	-1.1	-0.6	0.3	-0.6	0.3	-1.6	1.0	-0.9	-0.2	-1.7	-0.2	-2.0
Standing height	0.5	5.3	32.3	0.1	4.2	0.8	-1.6	-2.2	5.7	-0.2	3.3	-0.7	-0.1	-0.0	-2.2	2.4	-0.5	0.1	-2.3	-2.2	-2.2
Length of working week for main job	0.3	0.3	1.9	-0.3	0.8	1.4	-0.4	-0.4	-0.1	-0.3	-0.2	0.8	0.0	0.4	-0.4	-0.2	-0.4	-0.1	-0.4	1.1	-0.6
Exposure to tobacco smoke at home	0.3	0.3	0.7	0.3	-0.7	-0.5	0.7	0.7	0.3	0.3	-0.8	-0.3	0.4	0.1	0.6	0.1	0.6	-0.3	0.7	-0.8	0.6
Breastfed as a baby	0.8	1.0	5.0	0.4	-2.2	-1.2	1.0	1.3	-0.2	0.5	0.8	0.1	0.8	0.1	1.3	-0.8	1.2	-0.4	1.4	-0.4	1.3
Tense / ‘highly strung’	0.4	0.6	2.2	0.2	1.4	0.5	-0.9	-0.9	-0.3	0.2	-1.5	-0.7	-0.5	-0.9	-0.9	0.3	-0.9	0.9	-0.8	0.1	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.3	0.5	0.4	0.4	1.5	1.3	0.9	0.2	1.4	0.9	1.5	1.3	1.3	0.4	1.4	-1.3	1.3	-1.3	0.8
Hair/balding pattern: Pattern 4	0.5	1.3	2.4	-1.6	1.4	1.2	-0.9	-1.2	-0.8	-1.4	-1.4	-1.0	-0.9	-0.1	-1.2	1.3	-1.3	-0.1	-1.2	0.7	-1.5
Birth weight of first child	0.7	1.3	4.8	-1.6	2.2	0.8	-0.3	-0.8	1.1	-1.7	0.4	-0.2	-0.9	1.2	-0.8	1.8	-0.3	-0.9	-0.8	-0.8	-1.6
Peak expiratory flow (PEF)	0.5	1.3	6.9	-0.4	2.6	1.8	-0.4	-0.8	-1.2	-0.7	0.6	0.3	-0.1	0.8	-0.8	1.8	-1.1	-0.3	-0.9	1.0	-1.2
Pulse wave reflection index	0.5	0.6	1.9	1.4	0.3	-0.5	0.3	0.5	-0.3	1.2	0.0	1.3	1.1	-0.4	0.5	-1.3	0.4	0.2	0.6	-0.2	0.9
Ever highly irritable/argumentative for 2 days	1.2	1.4	4.6	1.6	-0.4	-2.2	0.9	1.2	1.2	1.5	0.8	0.7	1.5	0.3	1.2	-1.1	1.3	-0.2	1.2	-0.8	1.5
Loud music exposure frequency	1.1	1.2	3.9	1.9	0.7	-1.0	0.3	0.8	-0.4	1.8	0.1	2.0	1.1	-0.7	0.9	-1.6	0.7	0.6	0.9	-0.2	1.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.6	-1.6	-0.1	-0.0	0.8	0.5	-1.0	-1.6	-1.1	0.2	-0.4	1.2	0.5	0.8	0.4	-1.3	0.6	-0.4	-0.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.5	0.5	-0.5	-0.5	0.5	0.7	1.0	0.6	0.1	0.8	1.2	0.4	0.7	-0.3	0.9	-0.4	0.7	-1.1	0.8
Blood clot in the leg (DVT)	0.5	0.6	1.6	1.2	-0.8	-0.6	-0.7	-0.3	-0.0	1.3	-0.5	-1.0	-0.0	-1.2	-0.3	-1.2	-0.3	1.0	-0.3	0.6	0.4
Medication: Paracetamol	0.3	0.5	3.7	-0.3	-1.9	0.0	-0.3	-0.4	-1.3	-0.3	-0.3	-1.1	0.1	-0.4	-0.4	0.1	-0.6	0.2	-0.3	0.5	-0.4
Headache pain in last month	0.3	0.4	3.3	0.7	-0.4	-0.5	-0.5	-0.3	-1.8	0.5	-0.0	-0.7	0.6	-0.5	-0.3	0.2	-0.7	0.5	-0.3	1.0	-0.1
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	5.5	1.7	0.1	0.9	-1.6	-1.0	-1.9	1.6	-1.7	-0.5	-0.6	-2.3	-1.0	-1.3	-1.4	2.2	-1.0	1.7	0.1
Glaucoma (self-reported)	0.8	0.9	4.4	-0.7	-0.5	-0.4	-0.7	-0.9	-1.2	-0.8	0.2	-2.1	-0.8	-0.7	-0.9	0.8	-1.1	0.2	-0.9	1.2	-1.1
Gout (self-reported)	1.4	2.0	6.4	1.0	-0.2	0.9	1.9	2.0	-0.2	0.6	0.8	1.3	2.5	1.1	2.0	0.3	1.7	-1.4	1.9	-0.7	1.5
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.9	-1.7	0.1	1.3	0.3	-0.2	0.2	-1.7	1.1	-1.0	-0.6	1.2	-0.2	1.7	-0.2	-1.1	-0.2	0.2	-1.1
Medication: Amlodipine	0.6	0.9	4.9	-1.0	0.7	0.1	0.5	0.2	2.2	-1.0	-0.1	0.7	0.3	1.0	0.2	1.2	0.7	-1.1	0.1	-1.8	-0.5
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.5	0.5	0.1	-0.5	-0.5	-0.2	0.2	0.6	-0.2	-0.3	-0.1	-0.6	-0.2	-1.2	-0.1	0.7	-0.1	-0.3	0.3
Birth weight	0.5	1.1	3.5	-0.4	1.8	0.1	0.9	0.7	1.3	-0.6	0.8	1.9	0.6	1.6	0.7	0.8	0.9	-1.2	0.6	-1.5	-0.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.7	0.4	0.8	0.0	-0.2	0.0	-1.2	0.5	-1.1	0.4	0.3	-0.1	0.1	-0.8	-0.2	0.3	0.1	1.3	0.3
High blood pressure (siblings)	2.4	3.5	9.2	-1.0	1.2	0.3	2.6	2.1	0.2	-1.3	1.0	2.0	2.0	3.0	2.1	1.8	2.0	-3.0	2.1	-1.8	0.7
Forced vital capacity (FVC), Best measure	0.6	2.1	5.1	-1.4	2.2	1.8	-1.1	-1.7	-0.2	-1.5	1.1	-0.6	-0.8	0.7	-1.7	2.0	-1.7	-0.2	-1.8	0.6	-2.3
Body fat percentage	0.3	1.1	8.2	-0.8	2.9	1.5	-0.6	-0.7	-0.6	-0.7	-1.5	1.7	-0.3	0.1	-0.6	0.2	-0.7	-0.1	-0.7	0.4	-0.9
Leg fat percentage (right)	0.7	2.7	13.4	-1.8	3.7	2.3	-0.9	-1.2	-1.2	-1.8	-2.4	1.5	-0.9	0.6	-1.1	0.8	-1.3	-0.4	-1.2	1.0	-1.8
Arm fat-free mass (right)	0.3	1.6	10.9	-0.5	3.3	1.4	-0.9	-1.1	2.4	-0.6	-1.4	0.7	-0.2	0.1	-1.1	0.6	-0.5	-0.1	-1.2	-0.5	-1.4
Exposure to tobacco smoke outside home	0.4	0.5	4.2	-0.3	-2.0	-0.2	0.3	0.4	-0.6	-0.2	-1.7	0.5	-0.3	-0.3	0.4	-0.7	0.2	0.1	0.4	0.2	0.3
Comparative body size at age 10	1.6	4.4	10.0	-1.6	0.7	0.5	-2.7	-2.6	-1.7	-1.2	-2.9	-1.7	-3.2	-1.7	-2.6	-0.2	-2.7	1.9	-2.5	2.3	-2.1
Number of full brothers	1.5	1.9	4.1	1.1	-0.9	-0.8	1.6	1.8	0.5	1.2	-0.9	1.8	2.0	0.2	1.8	-0.8	1.7	-0.5	1.8	-0.9	2.0
Worry too long after embarrassment	0.6	1.0	2.4	-1.3	1.1	1.0	-0.7	-1.1	-0.8	-1.4	0.3	-1.1	-0.5	0.4	-1.1	1.4	-1.0	-0.3	-1.1	0.5	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.8	-0.8	0.0	-0.3	1.5	1.2	1.1	-1.0	1.6	1.1	0.9	1.7	1.2	1.3	1.2	-1.7	1.2	-1.6	0.3
Wheeze or whistling in the chest in last year	0.4	0.7	2.2	1.1	0.6	0.1	-0.9	-0.7	-1.0	1.0	-0.6	-0.6	-0.0	-1.0	-0.8	-0.2	-1.0	1.1	-0.7	1.5	-0.2
Number of children fathered	0.2	0.2	1.7	0.7	0.6	-1.3	-0.3	-0.2	0.5	0.7	-0.0	-0.2	-0.2	-0.6	-0.2	-0.5	-0.1	0.5	-0.1	-0.1	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.8	1.8	-0.1	-0.5	-0.4	-1.2	-1.0	-0.7	0.1	-0.5	-1.0	-1.2	-1.3	-1.0	-0.3	-1.1	1.2	-1.0	0.8	-0.6
Age at first live birth	0.8	1.4	11.6	-1.0	-3.4	-1.0	-0.4	-0.6	0.9	-0.9	0.1	-2.2	-1.6	-0.9	-0.6	-0.2	-0.3	0.4	-0.5	-0.5	-0.6
Pulse wave peak to peak time	0.7	0.9	1.8	-1.1	0.2	-0.0	-0.9	-1.2	-0.1	-0.9	-0.3	-1.3	-1.3	-0.2	-1.1	1.4	-1.1	0.3	-1.2	0.6	-1.3
Health satisfaction	0.4	0.5	1.5	-0.8	0.8	0.7	0.7	0.5	-1.1	-0.7	0.1	1.2	0.4	1.2	0.5	0.3	0.2	-0.9	0.5	0.4	0.0
Shortness of breath walking on level ground	0.5	0.6	1.9	-1.4	1.3	0.5	0.2	-0.1	-0.6	-1.4	-0.6	0.6	-0.2	1.2	-0.1	1.0	-0.1	-1.1	-0.1	-0.2	-0.8
Qualifications: College or University degree	0.3	1.0	3.5	-1.8	-1.5	0.4	0.2	-0.3	-0.9	-1.9	-0.3	-1.2	-1.0	0.6	-0.3	1.3	-0.5	-0.8	-0.2	0.6	-1.1
Eye problems/disorders: None of the above	1.1	1.2	8.5	-0.5	0.6	-0.3	0.9	0.6	2.9	-0.4	0.9	1.4	0.4	0.7	0.6	-0.1	1.3	-0.8	0.7	-2.2	0.3
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.5	-0.2	-1.1	0.2	1.0	1.1	0.2	-0.2	0.4	1.2	0.3	0.7	1.1	-0.5	1.0	-0.7	1.2	-0.3	0.9
Emphysema/chronic bronchitis	1.4	1.5	3.0	0.8	0.1	-1.2	1.2	1.7	1.1	0.7	0.6	1.5	1.5	0.4	1.7	-0.8	1.7	-0.7	1.7	-1.4	1.6
Medication for pain relief, constipation, heartburn	0.9	1.5	4.5	1.4	-0.2	-0.3	1.1	1.4	1.5	1.3	0.4	2.1	1.0	-0.1	1.5	-1.3	1.5	-0.0	1.4	-1.1	1.7
Neck or shoulder pain in last month	0.6	0.9	2.3	1.0	-0.2	0.6	-0.8	-0.4	-1.4	1.2	-1.3	-0.2	-0.5	-1.4	-0.4	-1.3	-0.7	1.5	-0.4	1.2	0.4
Medication: Blood pressure	1.6	2.9	9.7	-3.1	0.8	-0.2	1.0	0.1	1.6	-3.1	1.1	-0.3	-0.1	2.8	0.1	2.9	0.5	-2.5	0.0	-1.6	-1.5
Angina (self-reported)	0.2	0.2	0.8	0.1	-0.0	-0.5	0.3	0.5	0.9	0.3	-0.2	0.8	0.0	0.2	0.5	-0.6	0.6	-0.1	0.4	-0.7	0.6
Migraine (self-reported)	0.5	0.6	2.6	-1.2	-0.8	0.7	0.4	0.2	0.4	-1.2	1.6	-0.6	0.3	0.8	0.2	1.2	0.2	-0.9	0.1	-0.1	-0.5
Medication: Ibuprofen	0.7	0.9	2.1	0.1	0.1	0.2	-1.3	-1.1	-0.6	0.2	-0.6	-1.4	-1.1	-1.1	-1.1	-0.6	-1.2	1.2	-1.1	1.2	-0.6
Medication: Allopurinol	1.2	1.5	4.3	0.5	0.5	1.1	1.6	1.6	1.1	0.1	0.6	1.2	2.1	1.2	1.6	0.6	1.6	-1.5	1.5	-1.3	0.9
Medication: Omeprazole	0.7	0.9	4.6	-0.6	0.7	-0.2	0.8	0.6	0.7	-0.6	2.1	1.4	0.9	1.3	0.6	0.3	0.9	-1.3	0.6	-0.7	0.1
Medication: Seretide 50 evohaler	2.0	2.3	7.1	2.3	-0.2	-1.1	-1.5	-0.7	0.8	2.4	-1.6	-0.2	-0.3	-2.7	-0.7	-2.6	-0.7	2.5	-0.7	0.8	0.8
Mean time to correctly identify matches	0.1	0.2	0.8	0.8	0.3	0.1	-0.6	-0.5	0.6	0.8	0.4	-0.2	0.3	-0.9	-0.5	0.2	-0.3	0.6	-0.5	-0.0	-0.1
Heart disease (mother)	0.3	0.4	1.3	-0.9	0.3	0.5	0.1	-0.3	-0.7	-1.0	0.2	-0.6	-0.6	0.8	-0.3	1.0	-0.4	-0.6	-0.2	1.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.7	-1.3	0.4	0.7	0.7	0.2	-0.0	-1.2	0.8	0.2	-0.0	1.3	0.2	1.2	0.3	-1.2	0.2	-0.6	-0.4
Whole body fat mass	0.3	1.4	11.6	-0.8	3.4	1.6	-0.8	-1.0	0.2	-0.8	-1.3	1.6	-0.3	0.2	-0.9	0.4	-0.8	-0.2	-1.1	0.3	-1.3
Leg fat mass (right)	0.6	2.5	14.0	-1.2	3.7	2.0	-1.4	-1.6	-0.5	-1.1	-2.4	1.1	-0.9	-0.0	-1.5	0.5	-1.5	0.2	-1.6	1.1	-1.8
Arm predicted mass (right)	0.3	1.5	9.9	-0.4	3.1	1.2	-1.0	-1.2	2.2	-0.5	-1.6	0.7	-0.4	-0.1	-1.1	0.3	-0.6	0.1	-1.3	-0.3	-1.3
Pulse rate, automated reading	1.1	3.6	7.2	-2.6	0.1	2.0	-1.6	-2.1	-1.9	-2.3	-1.4	-1.9	-2.7	-0.3	-2.1	1.4	-2.3	0.5	-2.1	1.7	-2.5
Alcohol intake frequency.	0.6	1.4	6.5	-0.8	2.2	1.2	1.0	0.7	0.2	-1.0	0.5	2.5	1.0	1.7	0.7	1.2	0.8	-1.4	0.7	-0.7	-0.1
Comparative height size at age 10	0.6	3.4	8.1	0.0	2.9	-0.0	-2.5	-2.7	1.0	0.1	0.6	-2.1	-1.7	-1.4	-2.7	0.9	-2.3	1.6	-2.7	1.5	-2.1
Number of full sisters	1.7	2.1	5.0	-0.0	0.7	0.1	1.9	1.4	1.4	-0.4	0.7	1.8	2.2	2.1	1.4	1.1	1.7	-2.1	1.4	-1.8	0.6
Suffer from ‘nerves’	0.3	0.4	0.9	0.0	-0.1	0.8	-0.8	-0.7	-0.9	0.2	-0.3	-0.9	-0.7	-0.9	-0.7	0.2	-0.8	0.9	-0.6	0.5	-0.3
Overall health rating	0.5	1.1	3.1	-0.7	1.3	0.4	1.0	0.7	0.2	-0.8	1.0	1.3	1.2	1.8	0.7	1.7	0.8	-1.6	0.7	-1.0	-0.1
Chest pain or discomfort	0.4	0.6	1.5	-0.4	1.1	1.2	0.7	0.7	-0.7	-0.3	-0.8	1.2	0.7	1.2	0.7	-0.1	0.5	-1.1	0.7	-0.1	0.3
Had major operations	0.2	0.3	1.2	-0.4	-1.1	0.7	0.0	-0.1	-0.7	-0.2	-0.3	-0.5	-0.5	-0.3	-0.1	1.1	-0.4	0.1	-0.1	0.8	-0.0
Age at last live birth	1.9	2.7	17.0	1.2	-4.1	-3.1	0.6	1.1	0.7	1.3	1.8	-1.0	-0.0	-1.2	1.0	-2.0	1.0	0.7	1.1	-0.7	1.7
Family relationship satisfaction	0.4	0.5	3.9	-0.2	-0.7	0.1	0.1	0.4	-2.0	-0.0	-1.7	-0.7	-0.3	-0.1	0.4	-0.6	-0.2	0.2	0.3	0.6	0.4
Leg pain on walking	1.6	2.0	5.0	-1.8	1.1	2.2	-0.9	-1.3	-2.1	-1.7	0.9	0.1	-0.7	0.6	-1.3	1.4	-1.7	-0.4	-1.4	1.4	-1.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.3	0.0	1.1	-0.3	-0.7	-0.7	-0.7	0.0	-0.5	0.3	-0.6	-0.6	-0.7	-0.5	-0.7	0.7	-0.6	1.1	-0.4
Commuting to job workplace: Car/motor vehicle	1.2	1.4	3.6	-0.9	0.1	0.2	1.4	0.9	1.6	-1.1	1.1	1.4	1.2	1.9	0.9	0.8	1.3	-1.8	1.0	-1.5	0.0
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.2	-0.7	-1.3	-0.3	-1.0	-1.1	-0.2	-0.6	0.7	-1.7	-1.8	-0.9	-1.2	-0.3	-1.2	0.9	-1.2	0.6	-1.0
Medication: Aspirin	0.9	1.3	4.0	-2.0	0.9	0.2	0.8	0.0	-0.5	-1.9	0.8	-0.1	-0.2	2.0	-0.0	2.0	0.1	-1.8	0.1	-0.7	-0.9
Supplements: Vitamin C	0.4	0.5	2.0	0.3	0.7	-0.2	-0.7	-0.8	-1.0	0.2	-0.5	-0.5	0.0	-0.7	-0.8	0.3	-0.9	0.5	-0.8	1.4	-0.6
Knee pain experienced in last month	0.8	1.2	4.7	-0.0	0.8	1.2	0.9	1.0	-1.9	0.0	2.2	1.8	0.6	1.0	1.0	-0.2	0.4	-1.1	0.9	1.1	0.6
Hypertension (Self-reported)	2.3	6.3	20.9	-4.2	1.1	1.1	2.2	1.0	0.8	-4.3	1.0	0.9	0.8	4.6	1.0	3.6	1.4	-4.4	1.0	-2.4	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	2.4	0.4	-0.4	-1.0	-0.3	-0.1	0.3	0.4	1.6	0.2	-0.2	-0.6	-0.1	-0.6	0.0	0.5	-0.1	0.0	0.2
Illnesses of father: Heart disease	0.5	0.7	1.9	-1.3	1.2	1.0	-0.1	-0.6	0.3	-1.3	-1.4	-0.8	-0.6	0.8	-0.6	1.0	-0.4	-0.7	-0.6	0.1	-1.2
Illnesses of siblings: Diabetes	1.0	1.2	3.2	0.1	1.3	0.5	-1.5	-1.3	-0.9	0.2	-1.8	-0.5	-1.1	-0.9	-1.3	-0.1	-1.3	1.2	-1.3	1.6	-0.9
Smoking status: Previous	2.7	4.0	21.5	0.1	0.2	0.2	2.0	1.8	2.2	-0.1	4.6	1.5	2.6	2.2	1.7	0.7	2.2	-2.4	1.8	-2.5	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.9	-1.3	1.0	0.6	-0.4	-1.1	0.9	-1.4	1.1	-0.4	-0.5	0.7	-1.1	2.0	-0.7	-0.6	-1.0	-0.5	-1.6
Whole body fat-free mass	0.3	1.8	13.0	-0.6	3.6	1.5	-1.1	-1.4	2.0	-0.8	-0.8	0.7	-0.3	0.1	-1.4	0.7	-0.8	-0.1	-1.5	0.0	-1.7
Leg fat-free mass (right)	0.2	1.0	8.5	0.2	2.9	1.1	-0.7	-0.8	1.2	0.0	-0.7	1.1	0.4	-0.2	-0.8	0.2	-0.5	0.0	-0.9	0.3	-0.9
Arm fat percentage (left)	0.2	0.8	3.4	-0.0	1.7	0.7	-0.2	-0.0	-1.6	0.0	-1.8	1.8	0.2	-0.2	0.0	-0.9	-0.4	0.1	-0.1	0.9	-0.0
Average weekly red wine intake	0.2	0.3	2.5	-0.2	-0.0	1.0	0.3	0.1	0.2	-0.2	-0.4	1.6	-0.5	0.0	0.1	-0.8	0.1	-0.0	0.1	-0.2	0.1
Handedness (chirality/laterality): Left-handed	0.7	0.9	3.0	0.4	0.0	-0.6	-1.2	-1.1	-1.0	0.4	0.2	-0.7	-0.9	-1.0	-1.1	-0.8	-1.4	1.1	-1.1	1.7	-0.7
Mood swings	0.2	0.3	0.8	-0.1	0.9	-0.0	-0.7	-0.8	0.2	-0.1	0.4	-0.7	-0.7	-0.3	-0.8	0.6	-0.6	0.5	-0.8	0.4	-0.6
Loneliness, isolation	1.7	2.4	6.1	-2.3	1.9	2.4	-0.5	-1.0	-1.4	-2.3	-1.9	-0.3	-0.9	0.7	-1.0	2.5	-1.1	-0.7	-1.0	1.0	-1.9
Long-standing illness, disability or infirmity	0.5	0.8	3.5	-1.0	1.6	1.1	0.0	-0.5	-0.7	-1.0	-0.3	-0.2	-0.1	0.9	-0.5	1.9	-0.5	-0.8	-0.5	0.7	-1.0
Ever had bowel cancer screening	0.3	0.3	1.6	0.0	-0.8	1.3	-0.4	-0.4	-0.5	0.2	-0.4	-0.4	-0.3	-0.7	-0.4	0.2	-0.6	0.4	-0.5	0.7	-0.2
Diabetes diagnosed by doctor	1.0	1.7	7.0	-1.2	1.3	1.1	-1.3	-1.6	1.7	-1.0	-2.6	-0.4	-1.2	-0.3	-1.6	0.6	-0.9	0.6	-1.6	0.0	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.6	1.2	-0.4	-1.0	1.3	1.8	-1.0	1.1	1.7	1.1	1.5	0.3	1.8	-1.0	1.3	-0.5	1.8	-0.0	1.9
Friendships satisfaction	2.2	2.7	6.6	-0.7	-0.3	0.4	-1.8	-1.9	-1.1	-0.4	-2.6	-1.9	-2.2	-1.9	-1.9	-0.0	-2.1	1.8	-1.9	2.2	-1.4
Qualifications: nursing, teaching	0.4	0.6	5.3	-1.0	-2.3	-1.1	0.0	-0.1	-0.5	-0.9	-0.8	-1.1	-1.0	-0.2	-0.1	-0.2	-0.2	-0.1	-0.0	-0.1	-0.3
Commuting to job workplace: Walk	0.6	0.7	2.2	1.2	-0.3	-0.5	-1.1	-0.5	-0.4	1.3	-0.3	-0.6	-0.1	-1.2	-0.5	-0.9	-0.7	1.5	-0.6	0.9	0.2
Eye problems/disorders: Cataract	1.8	2.0	7.0	1.7	-2.6	-1.1	1.3	1.8	0.6	1.5	0.1	-0.2	1.9	0.3	1.7	-0.4	1.7	-0.3	1.7	-1.1	2.0
Mouth/teeth dental problems: Mouth ulcers	2.0	3.2	9.1	-0.1	0.0	0.1	2.3	2.1	0.3	-0.2	3.0	2.1	2.4	2.1	2.1	0.7	2.2	-2.3	2.2	-1.3	1.5
Medication for cholesterol	0.6	0.9	3.3	1.8	-0.5	-0.7	0.0	0.2	1.5	1.8	1.3	-0.4	0.8	-1.1	0.2	-0.4	0.4	1.0	0.2	-0.5	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.0	1.4	0.9	-0.6	0.3	0.7	-0.8	1.3	0.6	0.6	0.8	-0.3	0.7	-0.7	0.2	0.2	0.6	0.4	1.1
Back pain experienced in last month	0.2	0.3	1.6	0.3	0.9	1.2	-0.5	-0.6	0.6	0.3	0.3	-0.0	-0.1	-0.3	-0.5	0.4	-0.2	0.4	-0.6	-0.0	-0.4
Mineral and other dietary supplements	0.3	0.4	1.9	-0.9	0.3	1.2	-0.6	-0.3	0.3	-0.7	-1.4	-0.1	-1.1	-0.4	-0.3	-0.5	-0.3	0.4	-0.4	0.2	-0.3
Breast cancer (self-reported)	0.8	0.9	3.7	-0.7	0.8	-0.9	1.0	0.7	-0.3	-0.9	1.9	0.3	0.4	1.8	0.7	1.2	0.6	-1.5	0.9	-0.5	0.0
Asthma (self-reported)	0.4	0.8	2.5	1.6	-0.6	-0.1	-0.5	0.1	0.3	1.6	-0.6	-0.2	0.2	-1.4	0.1	-1.6	0.0	1.4	0.2	-0.1	1.0
Osteoporosis (self-reported)	1.5	1.9	7.1	-1.8	1.7	2.4	0.5	-0.2	-2.7	-1.8	-0.4	1.0	-0.2	1.2	-0.2	1.8	-0.8	-1.3	-0.2	1.1	-1.1
Osteoarthritis (self-reported)	1.6	2.0	6.5	0.5	0.6	0.6	1.9	1.8	-0.8	0.2	0.7	1.3	2.6	1.8	1.8	0.7	1.6	-2.1	1.8	-0.5	1.1
Medication: Aspirin	0.8	1.1	4.1	-2.0	0.5	0.1	0.7	-0.0	-0.3	-1.9	0.2	-0.5	-0.4	1.8	-0.1	1.9	0.1	-1.7	0.1	-0.7	-0.9
Medication: Gliclazide	0.1	0.2	1.0	0.1	-0.3	-0.1	-0.3	-0.4	0.4	0.2	-1.0	0.2	0.1	-0.5	-0.4	-0.4	-0.4	0.4	-0.3	0.4	-0.1
Illnesses of father: None of the above (group 1)	2.5	3.1	6.0	0.5	1.6	0.1	-2.5	-2.3	-1.6	0.7	-1.4	-1.0	-1.9	-2.2	-2.3	-0.2	-2.4	2.4	-2.3	2.0	-1.3
Smoking status: Current	1.9	3.1	5.7	-0.7	2.1	2.4	-2.0	-2.3	-0.7	-0.6	-1.6	-1.0	-1.5	-1.0	-2.3	1.5	-2.3	1.2	-2.4	1.9	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	11.3	-0.2	-0.8	0.2	-0.9	-1.0	-3.4	-0.1	-0.6	-0.7	-1.9	-1.2	-1.0	-0.5	-1.8	1.2	-1.0	1.8	-0.6
Whole body water mass	0.3	1.7	12.4	-0.5	3.5	1.4	-1.1	-1.3	2.0	-0.7	-0.9	0.8	-0.2	0.0	-1.3	0.6	-0.8	-0.1	-1.4	0.0	-1.6
Leg predicted mass (right)	0.2	0.9	8.4	0.2	2.9	1.1	-0.6	-0.7	1.2	0.0	-0.6	1.2	0.5	-0.1	-0.7	0.2	-0.5	-0.1	-0.9	0.2	-0.9
Arm fat mass (left)	0.3	1.3	8.2	-0.1	2.9	1.0	-0.8	-0.7	-0.9	-0.1	-2.2	1.8	-0.0	-0.3	-0.6	-0.6	-0.8	0.3	-0.7	0.9	-0.6
Number of self-reported non-cancer illnesses	1.0	1.7	5.3	-1.0	-0.4	0.4	1.7	1.5	0.5	-1.0	1.4	0.9	1.1	2.3	1.5	1.0	1.6	-2.2	1.5	-1.0	0.5
Average weekly champagne plus white wine intake	0.8	1.0	6.1	0.2	0.1	1.7	-1.0	-1.0	-0.0	0.4	-2.5	-0.2	-0.7	-1.4	-1.0	0.0	-0.9	1.2	-1.0	0.7	-0.5
Miserableness	0.4	0.6	2.2	-0.1	1.5	0.1	-0.8	-1.1	-0.1	-0.2	-0.3	-0.8	-0.1	-0.4	-1.1	1.0	-1.0	0.2	-1.1	0.9	-1.1
Guilty feelings	0.7	1.1	4.2	-0.6	2.1	1.0	-1.0	-1.2	-0.5	-0.7	0.3	-1.2	-0.9	-0.0	-1.2	1.1	-1.1	0.2	-1.2	0.8	-1.4
Wears glasses or contact lenses	0.8	1.0	5.4	-1.2	-2.3	-0.1	1.1	0.9	0.3	-1.1	-0.5	-1.2	-0.2	1.0	0.9	0.5	0.9	-1.1	0.9	-0.5	0.3
Ever taken oral contraceptive pill	0.2	0.2	2.0	0.1	-1.4	0.3	-0.2	-0.1	0.1	0.0	0.8	-0.0	-0.6	-0.2	-0.1	-0.6	-0.1	0.4	-0.1	0.4	-0.0
Hearing aid user	0.2	0.3	1.4	-0.4	0.1	-0.3	0.2	0.4	-0.5	-0.2	-1.0	1.2	-0.7	0.2	0.4	-0.8	0.2	0.1	0.3	-0.3	0.4
Mother’s age at death	2.0	2.5	5.0	-1.3	0.4	2.2	-1.7	-1.8	-1.9	-1.1	-0.4	-1.8	-1.9	-0.7	-1.8	0.8	-2.0	0.9	-1.8	2.2	-1.7
Financial situation satisfaction	0.6	0.8	2.4	1.6	-0.5	0.1	0.1	0.6	-0.3	1.5	-1.3	0.8	0.6	-0.9	0.6	-1.4	0.3	0.9	0.6	0.4	1.3
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.1	1.2	-0.9	-0.8	-0.5	0.1	-1.4	1.5	-0.9	-0.2	-0.2	-1.3	0.1	-1.8	-0.3	1.4	0.2	1.3	1.1
Commuting to job workplace: Public transport	0.4	0.5	2.3	0.6	-1.5	0.1	-0.5	-0.3	0.0	0.8	-0.7	-1.1	-0.1	-1.0	-0.3	-0.8	-0.3	0.9	-0.3	0.2	0.4
Eye problems/disorders: Glaucoma	2.1	2.5	4.8	-1.4	1.1	1.4	-1.5	-1.9	-1.8	-1.4	-0.1	-2.1	-1.7	-0.4	-1.9	1.3	-2.1	0.3	-1.9	2.0	-2.2
Medication: Blood pressure	0.6	1.2	3.4	-1.9	0.6	1.2	0.9	0.6	-1.2	-1.8	-0.6	1.1	0.3	1.8	0.6	1.0	0.4	-1.9	0.7	-0.3	-0.5
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.7	-0.3	1.4	0.1	1.0	0.9	0.0	-0.4	0.6	0.6	1.2	1.6	0.9	0.7	0.9	-1.6	0.9	-0.7	0.3
Supplements: Fish oil (including cod liver oil)	0.9	1.2	4.0	1.3	0.6	-1.5	0.9	0.7	1.1	0.9	1.7	0.8	2.0	1.0	0.7	0.5	1.0	-0.9	0.7	-1.2	0.6
High cholesterol (Self-reported)	0.8	1.4	6.8	-2.6	0.8	1.2	-0.1	-0.6	0.3	-2.5	-0.6	0.5	-1.1	1.3	-0.5	0.8	-0.5	-1.2	-0.6	-0.3	-1.6
Medication: Bendroflumethiazide	0.8	1.2	4.5	-2.0	0.8	0.4	0.8	0.3	-0.8	-2.1	0.6	0.4	0.1	1.8	0.3	1.6	0.2	-2.0	0.3	-0.4	-0.9
Medication: Paracetamol	0.3	0.4	1.2	-0.0	-0.9	0.0	-0.7	-0.6	-1.1	-0.1	-0.4	-1.0	-0.2	-0.6	-0.7	-0.1	-0.9	0.5	-0.6	0.6	-0.5
Medication: Lisinopril	1.8	2.3	8.1	-2.7	1.1	0.9	0.1	-0.7	0.2	-2.8	1.7	-0.3	-0.9	1.9	-0.7	2.7	-0.5	-1.6	-0.7	-0.1	-2.0
Medication: Atorvastatin	0.3	0.4	1.3	-0.3	0.6	-0.2	0.7	0.5	0.5	-0.2	1.1	1.0	0.6	1.0	0.5	-0.0	0.6	-0.9	0.6	-0.7	0.3
Illnesses of father: High blood pressure	0.8	1.0	2.7	-0.9	-1.6	-1.1	1.2	1.1	1.1	-0.9	0.2	0.6	0.7	1.2	1.1	0.2	1.2	-1.3	1.1	-1.2	0.4
Alcohol drinker status: Never	1.5	1.7	5.8	1.3	0.7	-0.7	1.3	1.5	0.5	1.1	2.2	2.4	1.5	0.7	1.5	-0.7	1.4	-0.6	1.5	-1.0	1.4
Ever smoked	0.4	0.6	3.0	0.6	1.7	1.2	-0.8	-0.9	-0.1	0.4	0.9	0.4	0.5	-0.4	-0.9	0.2	-0.7	0.3	-0.8	0.7	-0.7
Basal metabolic rate	0.4	1.9	14.5	-0.6	3.8	1.5	-1.2	-1.5	1.7	-0.7	-1.1	0.9	-0.3	-0.0	-1.5	0.6	-1.0	0.0	-1.6	0.1	-1.7
Leg fat percentage (left)	0.6	2.0	9.7	-1.8	3.1	2.1	-0.1	-0.5	-1.1	-1.7	-2.1	1.8	-0.3	1.2	-0.4	1.0	-0.6	-1.1	-0.5	0.5	-1.3
Arm fat-free mass (left)	0.4	1.9	14.2	-0.7	3.8	1.8	-1.1	-1.3	1.8	-0.8	-1.6	1.0	-0.5	0.1	-1.3	0.5	-0.8	-0.0	-1.4	0.0	-1.6
Number of operations (self-reported)	0.1	0.2	0.7	0.8	0.2	-0.6	0.0	0.3	-0.4	0.8	0.1	0.8	0.6	-0.1	0.3	-0.2	-0.0	0.1	0.2	0.8	0.4
Average weekly beer plus cider intake	0.5	0.8	3.6	1.4	-0.2	-1.9	0.2	0.6	-1.5	1.3	0.1	-0.7	0.9	-0.4	0.5	-0.8	0.0	0.2	0.5	0.7	0.9
Irritability	1.4	2.3	5.1	-2.3	1.0	2.1	-1.3	-1.7	-0.9	-2.1	-1.2	-1.6	-1.5	-0.2	-1.7	1.1	-1.6	-0.1	-1.7	0.9	-2.3
Risk taking	0.8	1.1	4.2	1.1	-0.9	-0.3	0.3	0.8	-2.0	1.1	-1.1	1.4	-0.1	-0.9	0.8	-2.0	0.2	0.6	0.8	1.0	1.3
Ever had prostate specific antigen (PSA) test	2.3	2.7	4.9	0.6	-0.4	0.6	2.1	2.2	0.9	0.5	2.0	1.8	2.1	1.6	2.2	-0.5	2.1	-1.7	2.2	-1.5	1.7
Fractured/broken bones in last 5 years	0.6	0.7	2.7	1.5	-0.4	-0.4	-0.1	0.5	-0.2	1.6	-0.1	0.9	0.4	-0.9	0.5	-1.5	0.3	1.0	0.5	0.2	1.3
Age started oral contraceptive pill	1.9	2.3	6.9	-1.5	-0.1	0.9	-1.7	-1.9	-1.1	-1.3	-0.9	-1.5	-2.6	-1.0	-1.9	-0.3	-2.0	1.0	-2.0	1.4	-1.9
Diastolic blood pressure, automated reading	1.3	4.2	14.0	-2.2	0.9	1.6	2.5	1.5	-0.9	-2.4	2.5	1.8	1.4	3.7	1.6	2.3	1.4	-3.4	1.5	-1.4	-0.3
Ever depressed for a whole week	0.0	0.0	0.2	0.3	-0.4	0.1	-0.1	-0.1	0.3	0.3	-0.0	-0.3	0.3	0.1	-0.1	-0.3	-0.0	0.1	-0.1	0.0	0.0
Unable to work because of sickness or disability	0.2	0.2	0.7	-0.1	0.8	0.0	0.5	0.6	0.0	-0.1	0.8	0.6	0.5	0.4	0.6	0.5	0.4	-0.5	0.5	-0.4	0.3
Commuting to job workplace: Cycle	0.2	0.2	0.7	-0.7	0.5	0.2	0.3	-0.0	0.4	-0.9	0.2	0.6	0.1	0.6	-0.0	0.5	0.1	-0.7	0.0	-0.2	-0.5
Myopia	0.1	0.2	1.3	0.2	-0.7	0.4	0.0	0.1	0.5	0.3	-1.1	-0.3	-0.3	-0.8	0.1	-0.1	0.3	0.5	0.1	-0.2	0.4
Vascular/heart problems diagnosed by doctor	2.3	6.1	21.3	3.9	-0.4	-0.7	-2.6	-1.5	-0.9	4.0	-1.2	-1.0	-1.0	-4.6	-1.5	-3.2	-1.8	4.4	-1.5	2.4	1.0
Cholesterol lowering medication	2.1	3.1	10.0	-3.2	1.6	2.2	-1.1	-1.6	-0.7	-2.9	-1.7	-0.7	-1.8	1.1	-1.6	1.5	-1.5	-0.8	-1.7	0.6	-2.6
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.2	-1.5	0.9	0.5	0.0	-0.4	0.5	-1.5	1.4	0.4	-0.1	1.1	-0.4	1.1	-0.0	-1.0	-0.4	-0.3	-1.1
Pain experienced in last month	0.6	1.0	7.4	-0.9	-0.2	-1.0	0.5	0.0	2.7	-0.9	0.8	0.2	-0.2	0.7	0.0	0.9	0.7	-0.8	0.0	-2.1	-0.4
Supplements: Calcium	0.6	0.6	2.0	0.7	0.2	-1.4	0.7	0.3	1.2	0.4	1.2	-0.4	1.4	0.4	0.3	1.1	0.6	-0.8	0.4	-0.9	0.2
Basal cell carcinoma (self-reported)	0.7	0.8	1.8	0.3	-1.2	-0.4	-1.1	-1.0	-1.0	0.5	0.4	-0.3	-0.8	-1.3	-1.0	-1.3	-1.0	1.2	-0.8	1.2	-0.3
Heart attack/myocardial infarction (self-reported)	2.0	2.6	7.8	-2.4	-1.1	0.1	2.0	1.3	0.9	-2.4	1.0	0.9	0.5	2.8	1.3	1.4	1.5	-2.7	1.3	-1.6	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.7	1.2	-0.6	-0.5	-0.8	-0.4	-0.1	1.2	-0.5	-0.9	-0.1	-1.2	-0.4	-1.3	-0.4	1.1	-0.4	0.7	0.3
Heart disease (siblings)	1.5	1.8	3.9	0.2	-0.5	0.2	1.9	1.9	1.0	0.2	-0.1	1.2	1.5	1.3	1.9	0.2	2.0	-1.4	1.9	-1.4	1.6
Alcohol drinker status: Previous	0.2	0.3	1.3	-0.5	-0.7	-0.5	0.1	0.3	1.1	-0.3	1.1	-0.2	-0.2	0.1	0.3	-0.0	0.5	-0.2	0.3	-0.7	0.2
Pack years of smoking	0.2	0.3	2.4	0.6	0.5	0.3	-0.2	-0.2	1.6	0.7	0.8	0.8	-0.0	-0.3	-0.2	-0.1	0.2	0.5	-0.1	-0.7	0.2
Impedance of whole body	0.2	0.8	8.4	1.0	-0.6	-0.8	-0.1	-0.1	0.7	0.9	2.9	-0.8	-0.0	-0.4	-0.1	0.5	0.2	0.6	-0.1	-1.0	0.4
Leg fat mass (left)	0.5	1.9	11.7	-1.1	3.4	1.8	-1.0	-1.2	-0.3	-1.1	-2.2	1.2	-0.5	0.3	-1.1	0.6	-1.1	-0.1	-1.2	0.8	-1.5
Arm predicted mass (left)	0.4	2.0	14.2	-0.8	3.8	1.7	-1.0	-1.3	1.9	-0.9	-1.7	0.9	-0.5	0.3	-1.3	0.6	-0.7	-0.2	-1.4	-0.1	-1.7