[Hub]/) : Traits : Heel T-Score :

chr20:39,114,404-40,683,594

Best TWAS P=1.96e-43 · Best GWAS P=2.59e-55 conditioned to 6.38e-14

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RP3-511B24.6 0.21 0.00 lasso 5 0.00 2.5e-01 -8.9 10.1 7.6e-24 -0.61 0.06 0.12 FALSE
2 GTEx Skin Sun Exposed Lower leg LPIN3 0.12 0.01 lasso 5 0.02 3.5e-03 1.0 7.6 3.6e-14 -0.35 0.74 0.03 FALSE
3 GTEx Thyroid LPIN3 0.29 0.08 lasso 10 0.04 3.3e-04 -14.2 12.0 5.0e-33 -0.76 0.95 0.01 FALSE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EMILIN3 0.08 0.06 lasso 5 0.08 2.7e-09 -6.7 -9.1 8.2e-20 0.59 0.95 0.05 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZHX3 0.04 0.02 lasso 2 0.02 2.4e-03 -14.2 -13.8 2.0e-43 0.84 0.03 0.23 TRUE
6 The Cancer Genome Atlas Pancreatic Adenocarcinoma LPIN3 0.10 0.02 lasso 5 0.07 6.1e-04 -9.0 -7.0 2.3e-12 0.41 0.02 0.17 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma PLCG1 0.03 0.00 blup 35 0.02 3.5e-03 -7.1 9.2 2.9e-20 -0.63 0.02 0.56 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma ZHX3 0.05 0.06 lasso 2 0.05 2.6e-06 -7.0 6.3 2.2e-10 -0.53 0.91 0.03 FALSE