Hub : Genes

FAHD2CP

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1600	0.0610	5.6e-08	0.080	NA	0.096	NA	0.099	4.4e-07	NA	3.2e-08	NA	1.7e-08
2	GTEx	Adipose Visceral Omentum	0.0860	0.0430	5.3e-04	0.069	NA	0.006	NA	0.062	1.9e-04	NA	1.5e-01	NA	4.0e-04
3	GTEx	Adrenal Gland	0.1062	0.0760	5.1e-03	0.018	NA	0.057	NA	0.006	7.1e-02	NA	4.1e-03	NA	1.8e-01
4	GTEx	Artery Tibial	0.0679	0.0339	3.4e-04	0.060	NA	0.054	NA	0.056	1.8e-05	NA	4.4e-05	NA	3.1e-05
5	GTEx	Colon Transverse	0.0530	0.0320	7.4e-03	0.014	NA	0.028	NA	0.031	6.6e-02	NA	1.7e-02	NA	1.3e-02
6	GTEx	Heart Left Ventricle	0.0975	0.0598	1.5e-03	0.024	NA	0.022	NA	0.032	2.0e-02	NA	2.4e-02	NA	7.5e-03
7	GTEx	Liver	0.1790	0.0820	3.1e-04	0.144	NA	0.129	NA	0.142	8.2e-05	NA	1.9e-04	NA	9.3e-05
8	GTEx	Lung	0.0902	0.0361	6.8e-09	0.105	NA	0.086	NA	0.100	1.9e-08	NA	4.3e-07	NA	4.3e-08
9	GTEx	Muscle Skeletal	0.0721	0.0317	3.2e-08	0.085	NA	0.079	NA	0.081	1.1e-08	NA	3.3e-08	NA	2.5e-08
10	GTEx	Ovary	0.3190	0.1410	4.3e-03	0.050	NA	0.021	NA	0.056	2.3e-02	NA	1.0e-01	NA	1.7e-02
11	GTEx	Pancreas	0.1040	0.0450	7.1e-05	0.147	NA	0.113	NA	0.127	9.2e-07	NA	1.7e-05	NA	5.2e-06
12	GTEx	Spleen	0.1800	0.0720	8.3e-05	0.184	NA	0.132	NA	0.161	1.9e-05	NA	3.0e-04	NA	6.4e-05
13	GTEx	Stomach	0.1010	0.0470	1.6e-04	0.060	NA	0.084	NA	0.080	7.9e-04	NA	7.9e-05	NA	1.2e-04
14	GTEx	Testis	0.1370	0.0460	5.2e-10	0.227	NA	0.208	NA	0.237	1.9e-10	NA	1.3e-09	NA	6.8e-11
15	GTEx	Thyroid	0.1070	0.0410	1.4e-03	0.010	NA	0.043	NA	0.031	5.7e-02	NA	3.0e-04	NA	2.0e-03
16	GTEx	Whole Blood	0.0280	0.0190	9.3e-03	0.012	NA	0.007	NA	0.011	2.3e-02	NA	6.7e-02	NA	3.1e-02
17	ROSMAP	Brain Pre-frontal Cortex	0.0862	0.0326	5.3e-08	0.054	0.058	0.057	0.057	0.060	1.5e-07	6e-08	7.7e-08	7.5e-08	3.7e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	1.8	2.9	8.0	-1.6	-1.9	-0.7	-1.6	-2.8	-2.1	-1.1	-1.9	-1.6	0.0	-1.6	-1.7	-2.1	-1.6	-2.1	-1.4	1.4
Bipolar Disorder or Schizophrenia	2.7	6.7	20.0	-2.0	-3.3	-0.6	-2.5	-4.5	-3.8	-1.9	-3.0	-2.5	0.0	-2.4	-2.6	-2.0	-2.5	-3.1	-1.9	1.4
Depressed Affect (Nagel 2018)	0.1	0.2	0.9	0.6	0.5	-0.2	0.6	0.7	0.8	-0.1	0.2	0.2	-0.4	0.1	0.4	0.2	0.5	0.1	0.4	-0.9
Depression (Nagel 2018)	0.5	0.7	2.8	-1.0	-0.6	-0.3	-0.4	-0.6	-0.3	-0.6	-0.9	-1.1	-0.5	-0.9	-0.9	-0.9	-0.9	-1.7	-0.8	-0.0
Intelligence (Savage-Jansen 2018)	0.7	2.1	4.3	-1.2	-1.5	0.5	-1.5	-1.5	-1.3	-1.8	-1.6	-1.8	-0.5	-1.9	-2.1	-1.0	-1.7	0.4	-1.9	0.7
Neuroticism (Nagel 2018)	0.1	0.2	1.1	0.0	0.6	-1.1	0.7	0.5	0.6	0.1	0.4	0.1	-0.2	0.0	0.2	0.2	0.4	-0.6	-0.2	-0.8
Schizophrenia (2018)	1.9	3.9	12.0	-1.3	-2.7	-0.2	-1.9	-3.5	-3.2	-1.5	-2.4	-1.9	0.0	-1.8	-2.0	-0.9	-2.0	-2.3	-1.3	0.7
Schizophrenia vs Biploar Disorder	0.4	0.5	2.2	-0.8	-0.1	-1.5	-0.4	0.5	0.2	-0.7	-0.6	-0.3	0.0	-0.2	-0.2	0.4	-0.4	1.4	-0.5	1.2
Worry (Nagel 2018)	0.2	0.5	1.8	0.4	1.2	0.0	1.0	0.9	1.4	0.7	0.9	0.4	0.8	0.3	0.4	0.4	0.7	-0.2	-0.1	-0.8
Alzheimer’s Disease (in mother)	2.6	3.0	9.2	1.5	2.1	1.5	2.0	2.3	1.9	1.5	1.8	1.2	3.0	1.2	1.4	1.2	1.7	1.9	0.8	-1.3
Alzheimer’s Disease (in father)	2.6	2.8	4.1	-1.8	-1.9	0.7	-2.0	-1.8	-1.9	-1.7	-1.8	-1.7	-1.4	-1.6	-1.9	-1.8	-1.9	0.6	-1.6	1.5
Alzheimer’s Disease (including proxy)	0.3	0.4	2.1	0.2	0.3	1.5	0.3	0.4	0.2	0.5	0.5	0.0	1.5	0.1	0.4	-0.0	0.3	0.8	0.2	-0.6
Crohns Disease (2017)	0.7	1.6	5.2	-0.8	-1.3	-0.2	-0.5	0.0	-1.7	-1.9	-1.2	-1.6	0.1	-1.6	-1.7	-2.3	-1.3	-0.6	-1.4	0.1
Irritable Bowel Disease (IBD)	0.3	0.7	2.5	1.0	0.8	0.7	1.2	1.6	0.4	0.2	0.6	0.5	1.4	0.5	0.2	-0.7	0.6	0.2	0.5	-1.3
Ulcerative Colitis (UC)	2.2	4.1	6.5	2.2	2.5	1.2	2.3	2.2	2.5	2.0	2.0	2.1	2.4	2.0	1.8	1.4	2.2	0.7	1.9	-2.1
Major Depression (MDD)	1.4	1.7	12.7	-0.7	-1.1	-1.6	-1.8	-3.6	-0.5	-0.7	-1.2	-0.9	0.0	-1.0	-1.2	-0.5	-1.1	-0.3	-0.9	1.1
Reaction Time	2.1	4.0	8.2	-2.0	-1.9	0.0	-1.4	-1.4	-2.9	-2.3	-2.1	-2.3	-1.1	-2.3	-2.1	-2.1	-2.0	0.7	-2.3	2.5
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.4	-0.9	-0.5	0.2	-0.7	-1.1	-0.2	-0.4	-0.6	-0.7	0.5	-0.7	-1.2	0.1	-0.6	0.1	-1.2	0.6
Breast Cancer	0.2	0.5	4.4	0.7	0.2	-0.0	-0.5	-0.9	0.1	-0.2	-0.0	0.2	0.1	0.2	0.4	1.4	0.3	2.1	0.4	0.8
Ovarian Cancer	2.5	3.3	5.3	-1.7	-1.8	-0.9	-1.8	-1.8	-1.5	-2.0	-2.1	-2.3	-0.8	-2.2	-2.2	-1.8	-2.3	0.3	-1.9	2.2
Prostate Cancer	1.8	2.5	4.5	1.9	1.7	1.2	2.1	1.5	1.3	1.5	1.6	1.8	1.4	1.8	1.7	0.8	1.9	-0.7	1.9	-1.4
Age at First Birth	2.9	4.2	6.2	2.1	2.3	1.9	1.9	2.3	2.1	2.0	2.2	2.3	0.0	2.3	2.5	1.7	2.5	1.6	2.4	-1.6
Bipolar Disorder (2011)	0.6	0.6	4.0	-0.0	-1.0	-0.2	-0.3	-1.2	-1.1	-0.5	-0.6	-0.4	0.0	-0.4	-0.4	-0.6	-0.3	-2.0	-0.1	-0.4
Body Mass Index (BMI) (2010)	1.4	1.9	2.7	-1.4	-1.5	-0.9	-1.6	-1.4	-1.5	-1.3	-1.5	-1.5	0.0	-1.4	-1.3	-1.6	-1.6	-0.5	-1.3	1.6
Coronary Artery Disease (CAD)	1.0	1.2	2.9	-0.7	-1.7	-0.0	-1.4	-0.7	-1.5	-1.3	-1.5	-0.7	0.0	-0.8	-1.5	-1.2	-1.3	0.2	-0.6	0.8
Crohns Disease (2012)	1.9	3.1	6.1	-2.2	-1.5	-2.2	-0.8	-0.4	-1.6	-2.5	-1.8	-2.1	0.0	-2.1	-2.0	-2.1	-1.7	-0.3	-2.4	1.0
Mean Putamen Volume	0.2	0.2	1.1	0.3	0.3	0.9	0.5	0.4	0.0	0.4	0.4	0.2	0.0	0.2	0.2	0.3	0.3	-0.6	0.0	-1.0
Fasting Glucose	0.3	0.4	2.8	0.7	0.3	1.7	0.3	0.1	0.3	0.5	0.7	0.4	0.0	0.4	0.3	0.7	0.3	0.5	0.6	-0.8
HbA1C	1.0	1.1	2.2	1.3	1.1	0.3	1.2	1.3	1.1	1.2	1.0	1.5	0.0	1.3	0.9	0.3	1.2	-0.6	0.6	-1.5
HDL Cholesterol	0.2	0.3	0.7	0.2	0.3	-0.4	0.1	0.8	0.7	0.6	0.2	0.7	0.0	0.7	0.4	0.6	0.3	0.8	0.5	-0.2
LDL Cholesterol	0.2	0.3	1.2	-0.3	-0.3	1.1	-0.0	0.1	0.3	-0.2	-0.5	-0.3	0.0	-0.5	-0.7	-0.4	-0.4	-1.1	-0.0	-0.7
Lupus	0.4	0.6	3.2	0.1	0.7	1.2	1.0	-1.0	-0.7	0.5	0.4	0.3	0.4	0.2	-0.0	1.8	0.8	-0.3	0.1	-0.7
Neuroticism (2016)	0.1	0.2	0.6	-0.4	-0.0	-0.4	-0.2	-0.3	0.4	-0.8	-0.5	-0.5	0.0	-0.7	-0.3	-0.1	-0.3	0.7	-0.3	0.2
Primary Biliary Cirrhosis	0.1	0.1	0.7	0.5	-0.2	0.1	0.1	0.2	-0.6	0.4	0.6	0.5	0.0	0.3	0.2	-0.2	0.3	0.8	-0.2	0.4
Rheumatoid Arthritis	0.2	0.3	1.7	-0.2	0.7	-0.6	0.6	0.1	1.3	0.1	0.3	0.1	0.0	0.1	0.2	-0.1	0.3	-1.3	-0.3	-0.5
Schizophrenia (2014)	1.4	3.2	10.0	-1.3	-2.2	-0.1	-1.8	-3.2	-2.7	-1.5	-2.2	-1.9	0.0	-1.7	-1.6	-1.4	-1.7	-1.8	-0.9	1.5
Triglycerides	0.3	0.5	1.0	0.6	0.5	0.6	0.9	0.7	0.4	0.8	0.8	0.7	0.0	0.8	0.9	0.8	0.6	-1.0	0.9	-1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	2.6	0.2	-0.3	-0.2	-0.2	0.5	-1.0	-1.1	-0.1	-0.4	0.0	-0.1	0.0	0.1	-0.1	1.6	-0.1	0.6
Ulcerative Colitis	1.8	2.6	4.2	1.9	1.8	0.9	1.9	1.9	1.5	2.1	1.7	1.9	0.0	1.9	1.7	1.1	1.8	0.5	2.0	-1.4
Blood Eosinophil Count	34.0	262.2	501.8	16.1	20.1	6.0	14.1	12.9	22.4	18.7	18.4	17.5	15.8	17.6	17.7	16.3	18.3	8.2	15.2	-11.2
Blood Platelet Count	0.0	0.2	1.1	0.1	0.5	-0.0	-0.2	-0.6	0.8	0.3	0.2	0.2	0.2	0.1	0.1	-0.1	0.3	1.0	-0.5	0.1
Blood Red Count	0.1	0.7	1.6	-0.1	-1.1	0.2	-1.2	-0.5	-1.1	-1.3	-1.0	-0.9	0.1	-0.9	-0.9	0.1	-1.1	0.7	-0.0	0.9
Blood White Count	0.1	1.1	2.2	-1.0	-0.8	-1.5	-1.5	-1.3	0.5	-1.0	-1.0	-1.4	0.0	-1.3	-0.7	-1.0	-1.3	-0.4	-0.8	1.2
Heel T-Score	2.8	22.0	30.1	5.3	5.3	1.0	4.8	4.3	5.1	4.8	5.4	5.4	4.8	5.5	5.4	4.3	5.4	0.8	5.0	-3.4
BMI	1.4	8.3	14.7	-2.9	-2.9	-2.4	-3.8	-2.2	-2.0	-3.3	-3.3	-3.0	-3.7	-2.8	-2.2	-2.3	-3.2	1.8	-2.2	3.8
Height	0.2	3.3	17.6	-0.8	-2.7	-0.5	-1.7	-1.9	-4.2	-1.0	-1.8	-1.5	-1.5	-1.4	-1.5	-1.6	-1.9	-0.4	-0.9	1.9
Waist Hip Ratio (WHR)	0.4	1.8	4.1	1.0	1.8	0.4	0.7	0.5	1.6	1.6	2.0	1.4	1.3	1.4	1.7	1.3	1.8	0.6	0.6	-1.0
Systolic Blood Pressure	0.2	0.8	4.1	0.2	-0.3	0.4	0.4	2.0	-1.3	-1.3	0.1	-0.0	1.7	-0.0	0.1	0.3	-0.2	1.6	0.7	-0.0
Smoking Status	0.3	0.6	1.2	-1.1	-0.3	-0.9	-0.6	-0.9	0.4	-0.5	-0.9	-0.8	-1.1	-0.9	-0.9	-0.6	-0.9	-0.8	-0.6	-0.1
Allergy or Eczema	2.1	5.6	13.5	-2.4	-1.5	-1.9	-3.0	-0.9	0.2	-3.1	-2.1	-2.4	-1.4	-2.3	-2.2	-1.8	-2.2	3.7	-2.9	3.5
Cardiovascular Disease	2.3	7.6	15.5	2.5	2.9	1.5	2.5	3.9	2.8	2.4	2.7	3.0	2.1	3.1	3.2	3.2	2.7	1.5	3.3	-2.4
Hypothyroidism (self reported)	0.3	0.8	1.7	0.3	1.0	0.4	0.8	1.2	0.8	0.8	0.8	0.9	0.1	1.0	1.1	0.5	1.2	1.0	1.3	-0.5
Respiratory disease	0.1	0.3	3.1	0.1	0.1	-0.3	-0.6	0.2	0.8	-0.4	0.2	0.2	0.2	0.1	-0.1	0.1	0.0	1.8	-0.4	0.4
Type 2 Diabetes (T2D) (2018)	0.3	0.6	3.1	0.3	0.0	1.6	-0.0	1.8	0.5	-0.4	-0.1	0.3	-0.5	0.3	0.0	-0.6	-0.0	1.3	0.6	-0.7
Lung FEV1/FVC ratio	0.2	0.9	6.4	0.3	0.3	0.4	1.1	1.2	0.2	-0.2	0.2	0.3	-0.6	0.2	0.3	-0.9	0.3	-2.5	0.7	-1.9
Lung FVC	0.4	2.2	6.0	1.5	1.7	2.4	2.2	1.2	0.7	1.1	1.3	0.8	1.6	0.7	0.7	1.8	1.6	0.4	1.0	-2.3
Neuroticism	0.3	0.8	2.9	-1.0	-0.6	-1.7	-0.8	-0.9	-0.4	-1.1	-0.5	-1.0	-0.7	-1.1	-0.8	-1.0	-0.6	-0.1	-1.4	0.3
Chronotype (morning person)	2.1	4.9	15.5	1.9	2.3	1.7	3.1	3.9	1.4	1.3	2.3	2.1	1.4	2.0	2.4	1.6	2.5	0.6	2.6	-2.0
Hair Pigment	0.1	2.9	4.1	-1.6	-1.9	-1.6	-1.7	-1.8	-1.4	-1.6	-1.8	-1.7	-1.8	-1.6	-1.6	-1.9	-1.8	-0.8	-1.5	2.0
Tanning	0.0	0.4	1.9	-0.3	-0.4	0.8	-0.0	-0.2	-0.9	-0.3	-0.5	-0.2	-1.4	-0.2	-0.3	-0.7	-0.3	-0.7	-0.4	-0.8
Hand grip strength (left)	0.3	0.9	2.2	1.2	0.7	0.7	1.0	1.0	0.9	1.3	0.6	0.9	0.7	1.0	1.1	0.7	0.8	-0.0	1.5	-0.7
Number of treatments/medications taken	0.1	0.2	0.8	-0.4	0.2	0.6	-0.3	0.9	0.7	-0.4	0.0	-0.3	-0.1	-0.2	0.1	-0.2	-0.1	0.7	-0.4	-0.2
Average weekly spirits intake	1.7	2.1	4.5	-1.8	-0.9	-0.0	-2.1	-1.4	0.1	-1.2	-1.3	-1.3	-2.1	-1.2	-1.2	-1.7	-1.3	0.6	-2.0	1.9
Sensitivity / hurt feelings	0.9	1.5	2.6	-1.6	-1.2	-1.3	-0.7	-1.0	-1.6	-1.5	-1.1	-1.4	-1.5	-1.4	-1.1	-1.2	-1.0	-0.7	-1.4	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.1	-0.8	-0.6	0.2	-0.7	-0.9	-0.3	-0.6	-1.0	-1.0	-0.5	-1.0	-1.0	-0.5	-1.1	-0.9	-0.7	0.5
Hearing difficulty/problems: Yes	0.2	0.3	1.9	-0.0	1.0	-0.4	0.4	0.7	1.4	-0.4	0.2	0.1	0.4	0.0	0.1	-0.2	0.2	0.9	0.3	0.3
Relative age of first facial hair	0.3	0.7	2.2	0.5	1.5	1.2	1.5	0.4	1.1	0.5	0.6	0.4	1.2	0.3	0.3	0.5	0.8	0.0	0.7	-0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.1	-0.1	-0.4	0.1	-1.1	-0.6	-0.1	-0.5	-0.2	-0.5	0.0	-0.4	0.1	-0.9	-0.4	0.0	-0.0	0.4
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.6	1.0	1.0	1.6	0.7	0.4	1.0	0.6	0.8	0.9	0.6	0.9	1.0	0.9	1.0	0.2	1.1	-0.9
Ever had hysterectomy (womb removed)	0.2	0.2	2.3	0.1	0.2	1.5	-0.0	0.5	0.1	-0.3	0.2	0.2	0.7	0.2	0.0	-0.5	0.1	0.5	0.0	-0.4
Systolic blood pressure, automated reading	0.3	0.9	2.7	0.1	-1.0	0.2	-0.7	1.6	-1.5	-1.5	-0.0	-0.2	1.5	-0.1	-0.0	-0.8	-0.5	1.6	0.3	0.9
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	1.0	0.2	-0.6	0.0	-0.3	-0.3	-1.0	-0.2	-0.2	-0.1	-0.2	-0.2	-0.2	0.2	-0.3	-0.1	-0.2	-0.2
Angina	1.0	1.4	5.0	-1.6	-1.1	-2.2	-0.6	-0.4	-1.6	-1.4	-0.8	-1.0	-0.3	-1.0	-0.9	-1.4	-1.0	-0.7	-1.3	0.8
Medication for hormone replacement therapy	0.4	0.4	3.7	-0.5	-0.1	1.9	-0.3	-0.2	0.1	-0.7	-0.5	-0.6	-0.7	-0.7	-0.5	-0.6	-0.4	0.3	-0.4	-0.0
Vitamin and mineral supplements	4.9	6.6	12.8	2.9	2.4	-0.2	2.1	2.4	2.0	2.7	3.0	3.1	2.5	3.2	3.6	2.6	2.8	1.1	3.3	-1.6
Supplements: Zinc	4.5	4.9	11.0	-2.4	-2.1	-1.4	-1.7	-2.4	-1.8	-1.7	-2.1	-2.1	-2.7	-2.1	-2.2	-3.1	-2.1	-3.3	-2.2	1.1
Medication: Co-codamol	0.7	0.8	1.7	1.0	1.0	-0.5	1.3	0.9	0.3	0.9	0.9	0.7	1.1	0.8	1.2	0.8	1.0	0.1	1.2	-0.8
Medication: Metformin	0.5	0.7	4.9	0.6	0.5	1.0	-0.4	1.8	1.2	-0.3	0.3	0.4	0.2	0.5	0.4	-0.2	0.2	2.2	0.1	-0.1
Diabetes (father)	0.2	0.2	1.5	0.5	0.2	-0.4	0.5	0.0	0.4	0.5	0.4	0.4	0.8	0.4	0.1	0.4	0.3	-1.2	-0.1	-0.5
Diabetes (mother)	0.3	0.3	1.0	-0.9	0.2	-0.6	-0.4	-0.2	0.0	-0.6	-0.3	-0.7	-0.1	-0.7	-0.5	-1.0	-0.5	-0.5	-0.7	0.8
Severe depression (siblings)	0.1	0.2	1.0	-0.1	0.2	-0.2	-0.1	-0.4	0.3	-0.6	-0.0	-0.4	0.3	-0.3	-0.1	-1.0	-0.1	-0.8	-0.0	0.3
Pack years adult smoking proportion	0.1	0.1	0.9	0.3	-0.2	0.1	0.5	0.6	-0.9	-0.1	0.0	-0.1	0.4	-0.1	0.1	-0.2	-0.0	0.0	0.2	-0.0
Impedance of leg (right)	2.4	11.7	18.1	3.1	3.9	1.6	3.6	3.0	3.5	4.2	3.9	4.1	3.4	4.0	3.5	3.5	3.9	0.8	3.1	-3.0
Leg fat-free mass (left)	1.4	7.4	12.4	-2.3	-3.2	-2.0	-3.3	-2.4	-2.8	-2.8	-3.1	-2.7	-2.9	-2.6	-2.2	-3.3	-3.1	0.3	-2.1	3.5
Trunk fat percentage	0.3	1.3	3.3	-0.9	-1.3	-0.5	-1.8	-0.3	-0.8	-1.4	-1.2	-0.9	-1.0	-0.8	-0.5	-1.6	-1.2	1.2	-0.4	1.8
Hand grip strength (right)	0.3	0.9	2.1	0.9	0.9	0.8	1.1	1.4	1.3	1.1	0.6	0.8	0.1	0.8	1.1	0.9	0.9	0.2	1.5	-0.9
Townsend deprivation index at recruitment	0.6	0.9	2.3	-0.9	-0.7	-0.8	-1.1	-1.5	-0.6	-0.3	-0.9	-0.9	-0.3	-0.9	-1.0	-1.3	-1.1	-1.0	-1.1	1.2
Current tobacco smoking	2.0	3.2	6.4	-1.9	-1.5	-2.1	-1.6	-2.5	-1.0	-1.3	-1.8	-1.8	-1.3	-1.8	-2.1	-1.9	-1.9	-2.3	-1.8	1.1
Average weekly fortified wine intake	1.1	1.3	4.5	-0.8	-1.1	0.3	-1.0	-2.1	-1.2	-0.5	-0.7	-0.9	-1.1	-0.8	-0.9	-1.9	-0.9	-1.6	-1.0	0.4
Maternal smoking around birth	0.5	0.7	2.8	0.1	1.0	-1.1	0.0	0.9	1.7	0.1	0.7	0.6	0.3	0.7	0.9	0.7	0.6	1.6	0.2	0.0
Fed-up feelings	0.3	0.5	2.5	-0.1	-0.4	-1.1	-0.8	-1.0	0.1	-0.4	-0.8	-0.5	-1.6	-0.4	-0.5	-0.4	-0.5	-0.4	-0.4	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.7	-0.6	0.1	-0.8	0.0	0.2	0.5	-0.1	-0.1	-0.2	0.3	-0.2	-0.4	-0.6	-0.2	-0.8	-0.6	-0.1
Relative age voice broke	0.1	0.1	0.8	-0.1	0.2	0.9	0.2	-0.5	-0.0	0.1	-0.3	0.0	-0.1	0.1	-0.1	-0.6	0.0	-0.2	0.2	0.6
Taking other prescription medications	0.1	0.1	0.8	-0.1	0.0	0.1	-0.2	0.5	0.2	-0.6	0.1	-0.2	0.2	-0.2	-0.0	-0.1	-0.1	0.2	0.2	-0.9
Age when periods started (menarche)	0.1	0.3	3.5	-0.2	-0.1	-1.9	-0.3	0.5	-0.2	0.3	0.2	0.5	-0.3	0.4	0.3	0.5	0.0	-0.2	0.2	0.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.5	0.8	0.9	0.4	0.9	-0.2	0.8	0.9	0.7	0.6	1.3	0.6	0.3	0.2	0.6	-1.9	0.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.0	12.3	2.0	3.1	1.2	2.4	1.5	3.5	2.9	2.8	2.7	1.8	2.7	2.8	2.2	2.8	-0.8	2.7	-2.2
Tinnitus: Yes, but not now, but have in the past	2.3	2.5	6.7	-1.5	-1.9	-0.6	-1.8	-2.6	-1.9	-0.3	-1.7	-1.2	-1.1	-1.2	-1.7	-1.5	-1.9	-1.8	-1.4	1.5
Qualifications: CSEs or equivalent	0.3	0.3	3.5	-0.0	-0.4	-1.9	-0.2	-0.6	-0.0	-0.0	-0.4	-0.2	0.4	-0.1	-0.3	-0.3	-0.5	-1.0	0.3	0.2
Serious illness, injury or assault to yourself	4.2	5.1	9.7	-2.5	-2.1	-1.8	-1.7	-3.1	-2.5	-2.4	-2.3	-3.0	-1.6	-3.0	-2.5	-1.1	-2.4	-1.2	-2.6	1.4
High blood pressure	2.4	6.6	12.5	2.4	2.7	1.0	1.8	3.5	2.7	1.8	2.8	2.7	3.1	2.8	3.0	2.5	2.6	2.8	2.6	-1.9
Hayfever, allergic rhinitis or eczema	1.4	3.1	10.2	-1.6	-1.1	-1.1	-2.1	-0.2	0.3	-2.4	-1.6	-1.8	-1.1	-1.7	-1.5	-1.3	-1.7	3.2	-2.0	2.5
Multivitamins +/- minerals	2.5	3.2	5.4	-2.2	-1.8	-0.1	-1.7	-1.8	-1.2	-1.6	-2.1	-2.0	-2.2	-2.1	-2.2	-1.8	-1.9	-1.2	-2.3	1.1
Stomach or abdominal pain in last month	1.6	1.9	3.6	1.1	1.9	-0.2	1.6	1.3	1.9	1.6	1.6	1.5	1.7	1.5	1.4	1.4	1.5	0.1	0.9	-1.2
Supplements: Glucosamine	0.8	1.0	2.4	0.7	1.4	0.2	1.0	-0.0	1.6	1.4	1.2	0.7	1.2	0.7	0.9	1.4	1.1	-0.4	0.9	-0.9
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.5	-0.1	0.4	-0.4	0.7	0.6	-0.1	-0.2	0.2	-0.0	0.4	-0.1	0.1	0.5	0.2	-0.4	0.2	-0.6
Medication: Atenolol	0.2	0.2	1.1	-0.4	-0.2	0.4	-0.4	0.1	-0.2	-0.7	-0.6	-0.5	-0.4	-0.4	-0.3	0.2	-0.4	1.1	-0.3	0.7
Medication: Levothyroxine sodium	0.2	0.4	1.6	-0.5	-0.7	-0.9	-0.8	0.2	-0.7	-0.0	-0.3	-0.0	-0.9	0.1	0.2	-0.4	-0.3	0.9	0.3	1.3
Sitting height	0.0	0.1	0.4	-0.0	-0.1	0.3	0.3	0.2	-0.6	0.5	-0.2	-0.1	-0.1	-0.1	0.1	-0.1	-0.1	0.1	0.3	0.2
Chronic bronchitis/emphysema (father)	2.0	2.3	9.1	-1.6	-1.3	-3.0	-1.7	-2.0	-0.8	-1.0	-1.1	-1.0	-1.2	-1.0	-1.2	-1.9	-1.3	-1.1	-1.4	1.7
High blood pressure (mother)	0.2	0.3	1.1	0.4	-0.5	-0.1	0.3	0.2	-1.0	-0.4	-0.2	-0.3	0.0	-0.3	-0.2	-1.1	-0.2	-0.9	0.4	-0.9
Body mass index (BMI)	1.2	5.3	10.0	-2.0	-2.4	-1.6	-3.1	-1.6	-1.7	-2.9	-2.6	-2.5	-2.1	-2.3	-1.8	-2.9	-2.6	1.1	-1.7	3.2
Impedance of leg (left)	2.4	11.6	17.6	2.9	3.8	1.6	4.0	3.2	3.2	4.2	3.8	4.0	3.3	3.9	3.5	3.6	3.9	0.3	3.1	-3.1
Leg predicted mass (left)	1.4	7.2	12.0	-2.2	-3.2	-2.0	-3.3	-2.4	-2.8	-2.8	-3.0	-2.7	-2.9	-2.5	-2.2	-3.2	-3.0	0.3	-2.1	3.5
Trunk fat mass	0.5	2.3	6.1	-1.2	-1.8	-1.0	-2.2	-0.7	-1.2	-1.8	-1.6	-1.4	-1.4	-1.2	-0.9	-2.1	-1.7	1.3	-0.8	2.5
Waist circumference	1.2	4.3	11.2	-1.8	-2.0	-2.1	-2.9	-1.6	-1.4	-2.2	-2.0	-1.9	-1.6	-1.7	-1.4	-3.0	-2.2	0.8	-1.7	3.4
Number of incorrect matches in round	0.1	0.2	0.6	0.2	0.3	-0.6	-0.1	0.3	0.7	0.3	0.4	0.5	0.2	0.5	0.6	-0.4	0.4	0.3	0.6	0.8
Past tobacco smoking	0.1	0.3	1.2	0.7	-0.2	-0.3	0.4	0.2	-0.6	0.4	0.6	0.5	1.1	0.6	0.5	0.1	0.4	-0.4	0.5	-0.1
Alcohol usually taken with meals	1.0	1.7	4.2	-1.3	-1.8	-0.3	-1.0	-0.2	-2.0	-1.2	-1.4	-1.1	-1.5	-1.0	-0.9	-1.7	-1.4	-0.9	-1.0	1.6
Nervous feelings	2.1	3.9	6.8	2.1	2.4	2.2	2.2	2.6	2.0	1.9	2.1	1.8	2.3	1.7	1.7	1.5	2.1	1.6	1.7	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.9	-0.0	-0.2	1.4	-0.4	-0.2	0.3	-0.2	-0.6	-0.4	-0.3	-0.4	-0.4	-0.6	-0.5	-0.1	0.2	0.3
Hearing difficulty/problems with background noise	0.7	1.1	2.9	-1.0	-0.7	0.2	-1.2	-1.2	-0.3	-1.1	-1.3	-0.9	-1.4	-0.9	-1.0	-1.7	-1.1	0.0	-0.5	1.4
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	0.5	0.7	-0.6	0.8	0.6	1.1	0.8	0.6	0.7	0.5	0.6	0.3	0.4	0.6	-1.4	0.5	-1.3
Had menopause	0.9	1.1	8.8	-0.1	-1.1	3.0	-0.8	-0.4	-1.5	-1.0	-0.9	-0.7	-0.8	-0.8	-1.1	-0.3	-0.7	0.7	-0.6	-0.1
Had other major operations	0.2	0.2	0.6	0.0	-0.6	-0.3	-0.7	-0.8	-0.8	-0.5	-0.5	-0.1	-0.6	-0.1	-0.3	-0.4	-0.2	0.8	-0.3	0.5
Forced vital capacity (FVC)	0.2	0.9	2.6	0.8	0.7	0.7	1.2	0.8	0.3	1.6	1.0	1.1	0.4	1.1	1.0	1.0	1.1	0.0	1.2	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.6	11.0	1.8	2.6	0.5	1.8	1.2	3.3	2.5	2.5	2.5	1.7	2.5	2.5	1.9	2.5	-0.5	2.3	-1.7
Ever unenthusiastic/disinterested for a whole week	7.2	8.8	15.5	-2.3	-3.1	0.2	-2.3	-3.9	-3.2	-2.4	-3.5	-3.1	-3.1	-3.1	-3.5	-3.6	-3.2	-3.4	-2.3	2.0
Qualifications: None of the above	2.3	5.0	8.8	2.2	2.4	0.4	1.8	1.9	2.7	2.3	2.6	2.6	1.5	2.8	3.0	1.6	2.6	-0.2	2.8	-2.1
Financial difficulties in last 2 years	0.4	0.5	2.0	-0.7	-0.6	-0.3	-0.5	-0.7	-0.7	-0.5	-0.7	-0.6	-0.8	-0.5	-0.2	-1.4	-0.6	-1.1	-0.3	0.7
Mouth/teeth dental problems	2.4	3.7	6.4	-1.9	-2.5	-0.6	-2.1	-1.9	-2.3	-2.0	-2.0	-1.9	-2.4	-1.9	-2.4	-1.5	-2.1	-0.5	-2.2	1.1
Heart attack	0.2	0.3	1.2	-0.4	0.6	-0.6	0.8	1.1	0.3	0.2	0.5	0.2	0.5	0.2	0.5	-0.5	0.4	-0.1	-0.2	0.0
Allergy	0.9	2.2	4.8	1.4	1.2	1.0	1.9	0.3	-0.1	2.2	1.5	1.4	1.2	1.3	1.2	1.4	1.5	-2.2	1.5	-2.0
Pain all over the body in last month	0.6	0.6	3.1	0.5	1.0	0.8	0.5	1.3	1.0	-0.4	0.6	0.4	0.0	0.4	1.0	0.1	0.8	1.8	0.6	-0.3
Diabetes (self-reported)	1.4	2.2	6.2	1.8	1.0	2.4	0.4	2.5	1.4	0.8	1.2	1.6	0.9	1.6	1.3	0.1	1.1	2.3	1.6	-1.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	4.4	-0.8	-0.6	-2.1	-0.8	0.1	-0.2	-0.4	-0.1	-0.4	0.5	-0.4	-0.4	-0.4	-0.7	0.2	-0.8	0.9
Medication: Ramipril	5.0	6.4	10.6	2.6	3.1	1.1	2.6	3.3	2.9	1.9	2.9	2.5	3.1	2.5	2.8	1.9	2.8	1.9	2.1	-2.0
Medication: Simvastatin	2.8	4.1	6.7	1.9	2.0	2.2	1.6	2.6	1.4	2.1	2.3	2.4	1.8	2.5	2.5	1.5	2.2	0.2	2.3	-1.7
Fluid intelligence score	0.1	0.2	1.0	0.4	-0.1	0.4	-0.1	-0.1	0.0	0.3	0.4	0.4	1.0	0.4	0.0	0.6	0.2	0.8	0.1	-0.1
Illnesses of siblings	0.4	0.6	3.6	-0.7	-0.6	-1.5	-0.4	0.4	-0.4	-0.7	-0.7	-0.2	-1.9	-0.2	-0.2	-0.6	-0.4	0.7	-0.7	0.6
Neuroticism score	0.8	1.7	3.2	-1.5	-0.8	-1.6	-1.2	-1.1	-0.3	-1.5	-1.1	-1.7	-1.1	-1.7	-1.4	-1.8	-1.2	-0.5	-1.8	0.9
Weight	1.0	4.8	9.9	-1.9	-2.4	-1.8	-2.8	-1.6	-1.9	-2.4	-2.5	-2.2	-2.1	-2.0	-1.7	-3.0	-2.5	0.6	-1.5	3.1
Impedance of arm (right)	0.5	2.5	5.2	1.2	1.3	1.8	1.9	2.3	1.2	1.5	1.6	1.8	1.5	1.6	1.1	1.7	1.6	0.2	1.0	-2.2
Arm fat percentage (right)	0.8	3.0	6.4	-1.6	-1.9	-0.9	-2.3	-0.6	-1.2	-2.5	-1.9	-1.9	-1.2	-1.7	-1.3	-2.2	-2.0	1.5	-1.4	2.3
Trunk fat-free mass	0.7	4.0	8.6	-1.6	-2.2	-1.6	-2.2	-1.7	-2.2	-1.9	-2.2	-2.1	-1.8	-1.9	-1.6	-2.6	-2.2	0.2	-1.4	2.9
Hip circumference	2.3	9.9	17.3	-3.0	-3.5	-2.7	-3.5	-2.3	-2.9	-3.5	-3.6	-3.2	-3.0	-3.0	-2.8	-4.2	-3.6	-0.4	-2.4	3.9
Time employed in main current job	0.4	0.4	5.0	-0.5	0.1	-0.2	-0.4	0.2	-0.3	-0.3	0.1	0.0	-0.4	0.1	0.2	0.6	0.2	2.2	-0.1	1.2
Alcohol intake versus 10 years previously	0.4	0.5	3.2	0.0	0.3	-1.8	-0.2	0.4	0.5	0.5	0.2	0.3	0.8	0.3	0.2	0.2	0.1	1.7	-0.3	1.1
Father’s age at death	0.6	0.8	1.9	0.9	1.2	1.4	0.7	0.6	1.3	0.9	0.7	1.0	0.0	1.0	0.8	0.5	0.9	0.6	0.9	-0.2
Worrier / anxious feelings	0.9	1.7	3.2	-1.4	-1.0	-1.3	-1.2	-0.8	-0.3	-1.4	-1.3	-1.6	-1.4	-1.6	-1.3	-1.8	-1.3	-0.4	-1.7	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	1.9	-1.1	-0.7	-1.1	-1.1	-1.2	-0.1	-1.0	-1.0	-1.4	-1.0	-1.4	-0.9	-1.3	-1.1	-0.8	-1.1	0.9
Falls in the last year	0.3	0.4	2.0	-0.7	-0.2	-0.5	-1.0	0.0	0.2	-0.4	-0.3	-0.4	0.0	-0.3	-0.0	-0.6	-0.4	1.4	-0.6	1.3
Hair/balding pattern: Pattern 3	1.4	2.1	4.8	1.9	0.5	0.9	0.3	1.1	0.4	2.0	1.8	2.1	1.4	2.2	2.1	0.8	1.4	1.0	1.8	-0.4
Number of live births	0.2	0.3	1.3	0.5	-0.6	0.7	-0.9	-0.7	-0.1	-0.6	-0.4	-0.2	-0.3	-0.1	-0.1	-1.1	-0.4	-0.5	0.1	-0.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	2.6	0.9	0.9	0.6	1.6	1.5	0.4	1.4	1.0	1.2	0.2	1.1	1.1	1.0	1.2	-0.2	1.4	-1.6
Pulse rate	3.7	6.2	9.2	2.6	2.8	1.4	2.9	2.3	2.3	2.8	2.6	2.6	2.7	2.5	2.2	3.0	2.8	1.4	2.1	-2.4
Happiness	1.1	1.4	3.9	-0.6	-0.5	0.7	-0.7	-1.0	-0.7	-1.8	-1.2	-1.9	-0.6	-2.0	-1.5	-1.5	-1.3	-0.2	-1.1	0.2
Noisy workplace	0.2	0.3	1.0	0.4	-0.2	-0.2	-0.4	-1.0	-0.1	0.5	-0.1	0.3	0.3	0.4	0.2	-0.2	-0.2	-1.0	0.9	0.8
Qualifications: A levels/AS levels or equivalent	0.2	0.4	3.9	0.3	-0.1	1.2	0.1	-0.2	-0.8	-0.3	-0.1	-0.2	0.2	-0.4	-0.6	0.7	0.1	2.0	-0.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	4.5	0.3	0.2	1.0	0.2	-0.9	0.5	1.0	0.8	0.6	0.5	0.7	0.5	-0.1	0.6	-2.1	0.4	-1.1
Mouth/teeth dental problems: Dentures	3.4	5.7	8.9	2.5	2.7	1.2	2.2	1.2	2.7	3.0	2.8	2.6	2.8	2.7	2.8	1.5	2.7	-1.0	2.6	-2.1
Asthma	0.4	0.7	1.9	-0.7	-0.7	-0.1	-1.4	-0.6	0.2	-1.3	-0.6	-0.7	-0.1	-0.7	-0.8	-0.8	-0.8	1.4	-1.1	0.8
Medication: Ibuprofen (e.g. Nurofen)	3.8	4.8	7.3	-2.7	-2.4	-0.5	-1.9	-2.1	-2.4	-2.1	-2.6	-2.5	-2.5	-2.5	-2.6	-1.8	-2.5	-1.1	-2.5	1.4
Medication: Cholesterol lowering	1.3	2.0	5.0	0.7	1.8	1.3	1.0	2.2	2.2	1.3	1.5	1.5	0.8	1.5	1.5	0.9	1.4	1.5	1.0	-1.1
Depression (self-reported)	0.3	0.4	1.6	-0.1	-0.2	1.3	-0.4	-0.4	0.2	-0.7	-0.9	-0.8	-1.0	-0.7	-0.5	-0.5	-0.6	0.7	0.4	0.4
Medication: Lansoprazole	2.3	2.6	5.2	1.4	1.5	1.2	1.6	-0.0	1.4	1.9	1.9	1.7	1.6	1.8	1.6	1.7	1.9	-0.8	1.8	-2.3
Prospective memory result	0.3	0.3	1.6	-0.2	-0.3	1.1	-0.6	-0.5	-0.3	-0.5	-0.5	-0.5	-1.3	-0.4	-0.5	-0.2	-0.5	-0.2	-0.3	0.4
Lung cancer (father)	0.3	0.3	1.5	0.3	0.8	0.3	0.7	-0.5	0.2	0.5	0.4	0.2	1.1	0.2	-0.0	1.2	0.5	0.5	0.5	-0.4
Illnesses of mother	2.4	3.0	6.9	-1.8	-1.6	-1.5	-2.1	-2.0	-1.1	-1.6	-2.1	-1.5	-2.6	-1.5	-1.6	-1.1	-1.8	0.5	-1.6	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	3.7	1.2	0.8	1.9	1.4	0.9	0.2	1.4	0.8	1.1	0.7	1.1	0.8	1.0	1.0	-0.2	1.4	-1.4
Pulse wave Arterial Stiffness index	0.2	0.2	1.8	0.0	0.4	0.2	-0.0	0.7	0.6	0.0	0.0	0.3	-0.5	0.3	0.2	0.5	0.3	1.3	-0.1	-0.0
Impedance of arm (left)	0.7	3.1	7.2	1.4	1.4	2.0	2.1	2.2	1.3	1.8	1.9	2.0	1.6	1.9	1.4	1.4	1.9	-0.2	1.4	-2.7
Arm fat mass (right)	1.0	4.2	8.6	-1.8	-2.3	-1.6	-2.8	-1.1	-1.4	-2.6	-2.2	-2.1	-1.9	-1.9	-1.4	-2.7	-2.3	1.3	-1.5	2.9
Trunk predicted mass	0.7	4.2	9.2	-1.7	-2.2	-1.7	-2.3	-1.7	-2.3	-1.9	-2.3	-2.1	-1.9	-2.0	-1.6	-2.7	-2.3	0.2	-1.5	3.0
Standing height	0.0	0.2	0.7	-0.2	-0.3	-0.6	0.1	0.0	-0.8	0.8	-0.2	0.2	-0.5	0.1	-0.0	-0.7	-0.2	-0.9	0.1	0.3
Length of working week for main job	0.4	0.4	1.1	-0.8	-0.6	-1.0	-0.7	-0.6	0.5	-0.3	-1.0	-0.5	-1.1	-0.4	-0.6	-0.2	-0.7	-0.1	-0.2	1.0
Exposure to tobacco smoke at home	0.8	0.9	1.9	-0.1	1.3	-1.2	1.4	1.3	1.1	0.9	0.8	1.1	-0.3	1.0	0.8	-0.1	1.0	-1.3	0.6	-0.6
Breastfed as a baby	1.0	1.3	2.9	-1.1	-1.2	-0.7	-1.0	-1.2	-1.6	-1.2	-1.0	-1.3	-0.2	-1.3	-1.3	-0.5	-1.0	0.8	-1.7	1.1
Tense / ‘highly strung’	0.6	1.0	2.9	0.8	1.3	0.6	1.1	0.7	1.2	0.9	1.2	0.7	1.7	0.7	0.7	1.2	1.0	0.2	0.3	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	6.7	-0.8	-1.0	0.1	-1.4	-2.6	-0.1	-0.6	-1.4	-1.1	-2.0	-1.1	-1.1	-1.5	-1.2	-1.7	-0.8	0.8
Hair/balding pattern: Pattern 4	0.4	0.9	2.0	-1.1	-0.6	-1.4	-0.5	-0.5	-0.8	-1.0	-0.7	-0.9	-1.3	-0.9	-0.6	-0.2	-0.6	1.3	-1.3	1.1
Birth weight of first child	0.1	0.2	0.6	-0.2	0.4	0.6	0.6	-0.8	-0.2	0.1	0.1	-0.2	0.6	-0.2	-0.4	0.0	0.3	-0.6	0.3	0.1
Peak expiratory flow (PEF)	2.2	5.0	10.0	1.8	2.5	0.8	3.2	2.9	1.8	2.6	2.2	2.2	0.9	2.2	2.5	1.8	2.6	-0.5	2.6	-3.0
Pulse wave reflection index	0.2	0.2	1.3	-0.1	0.8	-0.6	0.4	-0.1	1.1	0.5	0.2	0.3	-0.2	0.3	0.4	0.8	0.3	-0.1	0.2	-0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.0	-0.4	-0.6	-1.0	-0.7	-0.1	0.1	-0.4	-0.7	-0.2	-0.9	-0.1	-0.2	-1.4	-0.6	-0.5	-0.1	0.9
Loud music exposure frequency	3.5	3.8	6.2	-2.5	-2.4	-0.2	-1.9	-1.7	-2.4	-1.8	-2.5	-2.2	-2.0	-2.0	-1.6	-1.9	-2.5	-0.7	-1.3	2.0
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	4.8	-1.2	-2.0	0.4	-1.9	-2.2	-2.1	-1.2	-1.9	-1.3	-1.4	-1.4	-2.0	-1.2	-1.7	0.6	-1.4	1.6
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.5	1.1	1.1	-0.5	0.7	1.9	0.9	0.9	1.0	1.5	0.9	1.5	1.4	0.2	1.0	2.1	1.2	0.6
Blood clot in the leg (DVT)	0.4	0.5	1.6	0.9	0.5	1.3	0.3	0.5	0.6	0.2	0.6	0.5	0.7	0.6	0.8	-0.4	0.5	-0.8	1.2	-1.1
Medication: Paracetamol	0.6	1.0	3.0	-0.9	-1.2	0.0	-1.3	-1.7	-0.8	-0.5	-0.9	-0.8	-1.1	-0.8	-0.8	-1.4	-0.9	-0.4	-1.0	1.1
Headache pain in last month	0.5	0.8	1.8	-1.1	-0.9	-1.3	-0.5	-1.0	-1.3	-0.8	-0.7	-1.0	-0.3	-1.1	-1.2	0.1	-0.8	-0.3	-1.0	0.8
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	6.0	-1.4	-1.8	-1.0	-1.0	-2.2	-2.4	-1.8	-1.9	-2.0	-1.7	-2.1	-2.1	-1.4	-1.7	-1.1	-1.6	1.3
Glaucoma (self-reported)	0.6	0.7	2.2	-0.5	-0.3	-0.5	-0.0	0.9	-1.3	-1.4	-0.4	-1.0	1.1	-1.0	-0.1	-0.6	-0.6	1.5	-0.6	0.7
Gout (self-reported)	0.1	0.2	0.5	0.0	-0.5	-0.4	-0.4	-0.1	-0.6	-0.6	-0.5	-0.3	-0.2	-0.2	-0.4	-0.7	-0.5	0.2	-0.1	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	2.2	0.4	0.6	0.5	0.7	1.0	0.4	1.2	0.7	1.0	-0.1	1.1	1.2	0.4	1.0	0.5	1.5	-0.4
Medication: Amlodipine	1.1	1.6	3.2	1.2	1.7	0.5	0.8	1.5	1.5	0.9	1.5	1.1	1.8	1.1	1.5	1.3	1.3	1.5	0.8	-0.8
Medication: Ventolin 100micrograms inhaler	1.7	2.2	5.9	-1.9	-0.8	-2.4	-1.1	-0.7	-0.5	-2.4	-1.1	-1.9	-1.0	-1.9	-1.4	-0.2	-1.3	1.4	-1.9	0.6
Birth weight	0.1	0.2	1.6	-0.2	0.2	-0.7	0.7	-0.0	-0.1	0.2	0.3	0.1	-0.1	-0.0	-0.3	0.2	0.2	-1.1	-0.1	-1.3
Chronic bronchitis/emphysema (mother)	2.5	2.9	5.4	1.9	1.5	1.0	1.0	1.6	1.5	2.2	2.0	2.1	1.5	2.2	2.3	1.1	1.9	0.9	2.1	-0.8
High blood pressure (siblings)	0.7	0.9	2.8	1.1	1.1	1.1	0.4	0.5	1.4	1.1	0.9	0.8	1.7	0.8	0.8	0.9	0.8	0.9	1.1	-0.2
Forced vital capacity (FVC), Best measure	0.4	1.4	4.3	1.2	0.8	2.1	1.3	0.5	0.2	1.8	1.0	1.2	1.0	1.2	0.9	1.4	1.1	-0.1	1.4	-1.3
Body fat percentage	0.3	1.1	3.0	-0.8	-1.1	-0.6	-1.6	-0.2	-0.5	-1.4	-1.0	-0.9	-0.7	-0.7	-0.3	-1.4	-1.1	1.5	-0.4	1.7
Leg fat percentage (right)	0.1	0.5	2.2	-0.3	-0.4	-0.4	-1.2	0.0	0.2	-0.8	-0.5	-0.3	-0.3	-0.1	0.2	-1.0	-0.5	1.5	0.2	1.4
Arm fat-free mass (right)	0.9	4.8	10.7	-1.9	-2.3	-2.3	-2.5	-2.0	-2.2	-2.1	-2.4	-2.2	-2.3	-2.1	-1.6	-2.6	-2.3	0.3	-1.6	3.3
Exposure to tobacco smoke outside home	0.1	0.1	0.6	-0.3	0.4	-0.8	0.3	0.4	0.2	0.0	0.1	0.0	-0.1	-0.1	-0.4	0.0	0.0	0.1	-0.2	0.1
Comparative body size at age 10	6.3	17.3	25.8	-3.9	-5.1	-1.2	-4.5	-4.7	-4.6	-4.3	-4.8	-4.5	-4.5	-4.4	-4.4	-4.2	-4.8	-2.9	-3.1	3.2
Number of full brothers	0.8	1.0	2.1	0.9	1.1	-0.2	0.7	0.6	1.1	1.4	1.2	1.4	0.5	1.4	1.1	-0.2	1.1	-1.5	1.0	-0.8
Worry too long after embarrassment	0.2	0.4	1.9	-0.5	0.8	-1.4	0.6	0.3	1.2	-0.4	0.4	-0.4	-0.2	-0.4	0.3	-0.4	0.4	-0.6	-0.4	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	4.8	0.1	0.1	0.0	-0.9	-2.2	0.8	0.7	-0.1	0.2	-1.3	0.3	0.1	0.8	-0.0	-0.7	0.3	0.5
Wheeze or whistling in the chest in last year	0.4	0.6	1.3	-0.4	-0.5	-0.3	-1.1	-0.6	0.6	-1.2	-1.0	-0.9	-0.8	-0.8	-0.7	-1.1	-0.9	1.0	-0.6	0.7
Number of children fathered	0.3	0.4	1.7	-0.2	0.4	0.1	1.2	0.5	0.6	0.2	0.1	0.0	-0.4	0.0	0.1	0.3	0.3	-1.3	0.3	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.4	-0.6	0.2	0.0	0.4	0.2	-0.1	0.2	-0.1	-0.2	-0.7	-0.2	-0.0	-0.0	0.0	0.1	-0.4	0.2
Age at first live birth	0.5	0.8	2.5	-1.4	-1.0	-1.6	-0.3	-0.5	-1.2	-0.1	-0.6	-0.8	-1.1	-0.8	-0.9	-0.2	-0.7	-0.7	-1.3	0.7
Pulse wave peak to peak time	0.2	0.3	2.3	-0.1	-0.5	-0.3	-0.1	-0.8	-0.8	0.0	-0.1	-0.3	0.3	-0.3	-0.2	-0.7	-0.4	-1.5	0.1	0.2
Health satisfaction	3.6	4.7	7.2	-1.8	-2.4	0.4	-2.2	-2.7	-2.1	-2.2	-2.6	-2.4	-2.2	-2.4	-2.4	-2.3	-2.5	-1.4	-1.8	1.8
Shortness of breath walking on level ground	0.5	0.6	2.5	0.3	-0.7	1.6	-1.3	-1.5	-0.3	-0.3	-0.8	-0.6	-0.9	-0.6	-0.6	-0.3	-0.8	0.3	-0.3	0.8
Qualifications: College or University degree	0.2	0.7	1.6	-0.9	-0.7	0.3	-0.4	-1.0	-1.0	-0.4	-0.8	-1.0	-0.6	-1.1	-1.2	-0.5	-0.7	-0.0	-1.3	0.9
Eye problems/disorders: None of the above	0.5	0.6	1.3	0.9	0.9	0.1	0.8	0.1	1.1	1.1	0.9	1.0	0.9	0.9	0.5	0.0	1.0	0.0	0.7	-0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	-0.6	-0.2	0.7	-0.2	-0.1	-0.4	-0.7	-0.5	-0.7	-0.3	-0.8	-0.4	-0.1	-0.5	0.6	0.1	0.1
Emphysema/chronic bronchitis	0.4	0.4	1.7	-1.0	-0.4	-0.9	-0.4	0.1	-0.3	-0.6	-0.5	-0.4	-1.3	-0.5	-0.4	0.2	-0.2	1.0	-0.9	0.5
Medication for pain relief, constipation, heartburn	1.6	2.7	5.4	2.3	1.7	0.7	1.5	1.4	1.6	1.5	1.7	2.0	1.8	1.9	1.7	1.8	1.8	1.3	1.9	-0.8
Neck or shoulder pain in last month	0.8	1.1	2.9	-1.3	-0.4	-1.5	-0.6	-0.5	0.1	-1.7	-1.2	-1.5	-1.2	-1.5	-1.2	-0.6	-1.2	-0.9	-0.6	0.2
Medication: Blood pressure	0.8	1.4	5.6	0.9	1.0	0.6	0.3	1.7	1.2	0.5	1.2	1.1	1.6	1.1	1.3	1.2	0.9	2.4	0.6	-0.2
Angina (self-reported)	1.2	1.6	5.2	-1.7	-1.3	-2.3	-0.7	-0.7	-1.8	-1.3	-0.9	-1.1	-0.6	-1.0	-1.0	-1.5	-1.1	-1.2	-1.3	0.8
Migraine (self-reported)	3.5	4.4	7.3	-2.0	-2.2	-1.0	-1.4	-2.5	-2.0	-2.0	-2.4	-2.5	-1.7	-2.5	-2.7	-1.9	-2.2	-2.6	-2.0	0.9
Medication: Ibuprofen	5.5	6.5	11.4	-3.0	-3.0	-1.3	-2.7	-2.5	-2.8	-2.3	-3.0	-2.6	-3.4	-2.6	-2.8	-2.0	-2.8	-0.6	-2.6	2.2
Medication: Allopurinol	0.4	0.6	1.3	-0.3	-0.7	0.1	-0.8	-0.4	-0.8	-1.1	-0.9	-0.9	-0.1	-0.9	-1.0	-0.7	-0.9	0.8	-0.9	0.6
Medication: Omeprazole	0.6	0.8	2.5	-0.3	-1.1	0.6	-0.7	-1.6	-1.5	-0.8	-0.9	-1.0	-0.4	-0.9	-0.9	-0.1	-1.0	-0.8	-0.0	-0.3
Medication: Seretide 50 evohaler	0.2	0.3	2.7	0.1	-0.0	-0.1	-0.6	-0.4	0.2	0.1	0.0	-0.0	0.7	-0.0	0.0	0.7	-0.0	1.6	-0.5	0.5
Mean time to correctly identify matches	1.0	2.0	4.5	-1.3	-1.0	1.1	-0.7	-1.0	-2.1	-1.8	-1.4	-1.7	-0.4	-1.7	-1.6	-1.9	-1.3	0.3	-1.6	1.6
Heart disease (mother)	0.7	0.8	2.2	0.5	0.5	-0.4	1.0	0.6	-0.3	0.8	1.2	0.8	1.4	0.8	0.8	1.1	0.9	-1.0	0.7	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.1	-1.3	-1.0	-0.5	-1.2	-1.2	-0.9	-0.8	-1.1	-1.0	-0.7	-1.0	-1.3	-1.0	-1.1	-0.1	-1.4	1.4
Whole body fat mass	0.6	2.5	6.5	-1.3	-1.6	-1.0	-2.3	-0.8	-1.0	-1.9	-1.7	-1.4	-1.4	-1.2	-0.9	-2.1	-1.7	1.5	-0.9	2.5
Leg fat mass (right)	0.5	1.9	6.4	-1.1	-1.3	-1.1	-2.1	-0.7	-0.7	-1.6	-1.4	-1.2	-1.1	-1.0	-0.7	-1.8	-1.4	1.6	-0.8	2.5
Arm predicted mass (right)	0.8	3.9	9.2	-1.6	-2.1	-2.1	-2.3	-1.8	-2.1	-1.9	-2.2	-2.0	-2.0	-1.8	-1.4	-2.4	-2.1	0.4	-1.3	3.0
Pulse rate, automated reading	4.4	14.1	21.6	3.5	4.7	1.6	4.1	4.0	4.5	4.4	4.2	3.9	3.9	3.8	3.8	3.2	4.2	0.9	3.6	-3.3
Alcohol intake frequency.	1.5	3.4	5.7	-1.6	-2.3	-1.1	-2.2	-2.4	-2.1	-1.9	-2.2	-1.9	-1.2	-1.8	-2.0	-1.5	-2.1	0.0	-1.4	2.1
Comparative height size at age 10	0.2	1.2	3.4	-0.8	-1.3	-0.2	-1.3	-0.9	-1.8	-0.8	-1.2	-0.9	-1.3	-1.1	-1.2	-1.3	-1.2	0.6	-1.2	0.8
Number of full sisters	0.7	0.9	3.5	-0.6	-1.3	-0.4	-1.9	-1.5	-1.2	-0.4	-0.9	-0.7	-1.0	-0.7	-0.7	-0.8	-1.2	-0.4	-0.2	0.8
Suffer from ‘nerves’	0.3	0.5	1.8	0.2	1.3	0.3	1.2	0.7	1.3	0.0	0.4	-0.2	0.8	-0.2	-0.1	0.1	0.4	-1.0	-0.0	-1.0
Overall health rating	0.3	0.7	2.1	-0.6	-0.8	-0.2	-1.3	-1.5	-0.7	-1.1	-0.8	-1.2	-0.5	-1.0	-0.4	-0.5	-0.8	0.2	-0.6	0.9
Chest pain or discomfort	0.6	0.8	1.6	0.3	0.9	-1.2	0.2	0.4	1.2	1.2	1.0	0.9	1.2	1.0	1.2	0.9	0.8	0.7	0.6	0.1
Had major operations	3.1	3.6	5.8	1.7	1.8	1.3	1.9	1.5	1.7	2.4	2.0	2.2	1.2	2.3	2.1	2.1	2.2	-0.7	2.2	-2.0
Age at last live birth	1.5	2.2	4.0	-1.8	-1.7	-1.4	-1.4	-1.2	-1.5	-0.8	-1.6	-1.3	-2.0	-1.4	-1.6	-1.3	-1.4	-0.9	-1.8	1.5
Family relationship satisfaction	3.3	4.0	6.4	-1.8	-1.9	-0.5	-2.3	-2.3	-1.3	-2.3	-2.3	-2.3	-1.6	-2.2	-2.2	-2.5	-2.4	-0.1	-2.0	2.0
Leg pain on walking	0.3	0.4	2.1	0.1	0.2	1.5	0.4	-1.0	-0.4	-0.2	-0.5	-0.9	0.3	-0.9	-0.6	0.1	-0.3	-0.9	-0.3	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	5.9	-1.5	-1.8	-1.4	-2.0	-1.0	-1.2	-1.4	-1.7	-1.1	-1.7	-1.1	-1.4	-0.8	-1.7	1.6	-1.1	2.4
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.7	-0.2	0.0	-0.4	0.6	1.3	-0.0	0.3	-0.1	0.3	-0.6	0.3	0.1	0.2	0.1	-0.2	0.2	-0.9
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.8	0.4	-0.1	0.7	-0.1	0.9	0.1	0.4	0.0	0.4	0.1	0.3	-0.0	0.3	-0.0	0.8	-0.0	-0.2
Medication: Aspirin	0.3	0.4	1.4	-0.9	-0.3	-0.1	-0.5	1.2	-0.4	-0.8	0.0	-0.6	-0.5	-0.6	-0.1	-0.9	-0.3	0.4	-0.9	-0.1
Supplements: Vitamin C	3.4	4.0	7.7	-2.4	-1.9	0.8	-1.5	-1.1	-2.0	-2.3	-2.0	-2.3	-2.2	-2.4	-2.5	-2.3	-1.9	-0.1	-2.8	1.5
Knee pain experienced in last month	1.0	1.6	3.3	1.1	1.1	-0.7	0.8	0.9	1.0	1.6	1.4	1.5	1.0	1.7	1.7	1.3	1.3	-0.1	1.8	-0.8
Hypertension (Self-reported)	1.8	5.1	11.6	2.1	2.2	1.0	1.3	3.4	2.2	1.4	2.4	2.3	2.7	2.4	2.7	2.1	2.1	3.2	2.3	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	3.0	-0.9	-0.8	-0.9	-0.3	-1.7	-1.1	-0.4	-0.3	-0.7	0.3	-0.7	-0.7	-0.0	-0.6	-1.6	-0.6	0.2
Illnesses of father: Heart disease	1.3	1.8	3.4	-1.6	-1.2	-0.8	-0.5	-1.0	-1.4	-1.4	-1.3	-1.8	-1.2	-1.8	-1.5	-1.0	-1.4	-1.4	-1.8	0.4
Illnesses of siblings: Diabetes	1.0	1.2	2.9	1.7	0.8	1.0	0.8	0.4	0.4	1.3	1.3	1.4	1.1	1.3	1.0	-0.3	1.1	-1.2	1.2	-1.3
Smoking status: Previous	0.1	0.2	0.8	-0.2	0.0	0.8	-0.0	0.3	0.1	-0.2	-0.3	-0.2	-0.8	-0.2	-0.1	0.3	-0.1	0.9	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.9	6.5	-2.2	-1.7	-2.4	-1.4	-0.9	-0.8	-1.5	-1.7	-1.7	-1.6	-1.7	-1.6	-2.5	-1.9	-1.3	-1.7	1.3
Whole body fat-free mass	1.0	5.8	11.4	-2.0	-2.7	-2.0	-2.8	-2.1	-2.6	-2.4	-2.7	-2.5	-2.4	-2.3	-2.0	-3.0	-2.7	0.2	-1.8	3.4
Leg fat-free mass (right)	1.5	7.8	11.4	-2.4	-3.3	-2.1	-3.2	-2.3	-3.1	-3.0	-3.2	-2.9	-3.0	-2.8	-2.4	-3.3	-3.2	-0.1	-2.2	3.4
Arm fat percentage (left)	0.7	3.0	6.2	-1.6	-1.9	-0.8	-2.4	-0.6	-1.1	-2.5	-1.9	-1.8	-1.4	-1.6	-1.2	-2.3	-1.9	1.6	-1.2	2.2
Average weekly red wine intake	1.4	2.0	3.6	1.3	1.1	1.6	1.3	1.8	1.0	1.8	1.4	1.8	0.6	1.9	1.8	0.6	1.5	-0.4	1.7	-1.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.9	-0.7	-0.5	0.0	-0.2	0.3	-0.8	-0.4	-0.4	-0.4	-1.0	-0.4	-0.2	-0.9	-0.4	-0.5	-0.4	0.9
Mood swings	0.7	1.2	2.3	-1.1	-0.8	-1.3	-0.7	-1.3	-0.5	-1.2	-1.0	-1.3	-1.5	-1.3	-0.9	-1.5	-0.9	-1.0	-1.0	0.7
Loneliness, isolation	0.1	0.1	0.6	-0.1	0.1	0.1	-0.2	-0.4	0.3	-0.2	-0.1	-0.2	-0.4	-0.3	-0.1	0.1	-0.0	0.8	-0.1	0.5
Long-standing illness, disability or infirmity	0.5	0.8	2.5	-1.0	-0.7	0.1	-1.6	-0.7	-0.0	-1.1	-0.9	-1.0	-0.9	-1.0	-0.6	-1.1	-1.1	-0.3	-0.8	0.4
Ever had bowel cancer screening	0.4	0.5	2.4	0.1	-0.9	0.3	-0.7	-1.4	-1.6	-0.3	-0.5	-0.2	-0.9	-0.2	-0.3	-0.2	-0.3	-0.4	-0.2	0.6
Diabetes diagnosed by doctor	0.9	1.4	5.7	1.2	0.9	1.8	0.2	2.4	1.6	0.5	0.9	1.2	0.2	1.1	0.9	0.1	0.8	1.8	1.1	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.4	-0.2	-0.2	-0.1	-0.6	-1.0	-0.4	0.4	-0.5	0.0	0.0	0.1	-0.2	-0.7	-0.4	-0.3	0.0	1.2
Friendships satisfaction	3.6	4.5	8.2	-1.5	-2.7	-0.8	-2.3	-2.1	-2.9	-2.1	-2.4	-2.0	-1.5	-2.0	-2.2	-2.6	-2.5	-1.1	-2.0	2.2
Qualifications: nursing, teaching	4.3	6.6	10.0	-2.5	-2.6	0.1	-1.9	-3.0	-2.6	-2.6	-2.8	-3.1	-2.2	-3.2	-3.0	-3.1	-2.7	-1.8	-3.0	1.4
Commuting to job workplace: Walk	0.8	0.9	4.1	0.1	-1.1	1.4	-0.6	-0.3	-2.0	-1.3	-0.9	-0.6	0.0	-0.7	-1.1	-0.7	-0.7	1.1	-0.4	0.8
Eye problems/disorders: Cataract	0.1	0.1	0.4	-0.5	-0.0	0.2	0.2	0.3	-0.3	-0.4	0.2	-0.3	-0.1	-0.4	-0.1	0.1	0.0	-0.1	-0.6	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	3.5	-0.4	0.7	-0.8	0.4	0.6	0.9	-0.7	-0.4	-0.5	0.1	-0.4	-0.0	0.9	-0.1	1.9	-0.1	1.1
Medication for cholesterol	0.6	0.8	2.1	-0.5	-1.2	-1.3	-0.9	-1.5	-1.1	-0.3	-0.8	-0.6	-0.6	-0.7	-1.2	-0.7	-0.9	0.1	-1.2	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.6	4.1	1.5	1.1	-0.6	0.6	0.8	1.5	1.4	1.3	1.7	0.6	1.9	1.7	-0.3	1.2	-0.9	2.0	-0.5
Back pain experienced in last month	0.3	0.4	1.7	0.3	0.5	-0.0	0.5	0.1	0.6	0.7	0.5	0.2	1.3	0.3	0.7	0.8	0.4	-0.7	0.8	-0.7
Mineral and other dietary supplements	0.8	1.0	2.7	1.3	0.5	0.9	0.5	1.6	0.1	0.8	0.9	1.2	0.7	1.3	1.3	0.3	0.9	1.6	1.1	0.1
Breast cancer (self-reported)	0.2	0.2	0.9	0.2	0.0	-0.9	-0.2	-0.3	0.1	0.8	0.3	0.4	0.0	0.5	0.3	0.2	0.2	-0.9	-0.1	-0.3
Asthma (self-reported)	0.6	1.1	3.2	-1.0	-0.9	-0.6	-1.7	-0.8	0.1	-1.5	-0.7	-0.9	-0.2	-0.9	-1.0	-0.8	-1.0	1.8	-1.3	1.2
Osteoporosis (self-reported)	1.1	1.3	3.6	1.1	1.2	1.8	1.8	1.9	0.7	-0.1	1.0	0.6	1.0	0.5	0.7	0.2	1.2	-0.4	1.1	-1.9
Osteoarthritis (self-reported)	1.1	1.5	5.4	1.0	1.3	0.6	1.0	0.0	1.3	1.0	1.4	1.0	0.8	0.9	1.1	2.0	1.3	-0.7	1.1	-2.3
Medication: Aspirin	0.3	0.4	1.2	-1.0	-0.5	-0.1	-0.7	1.1	-0.4	-0.8	-0.1	-0.6	-0.7	-0.6	-0.1	-0.8	-0.4	0.6	-0.9	0.1
Medication: Gliclazide	0.2	0.2	1.9	0.7	0.3	1.4	0.2	0.3	0.0	0.0	0.1	0.2	0.2	0.1	-0.1	0.0	0.2	0.4	0.3	-0.5
Illnesses of father: None of the above (group 1)	1.2	1.5	3.0	1.2	1.4	1.0	1.3	1.2	0.9	1.2	1.1	1.3	0.5	1.3	1.3	1.7	1.4	0.7	1.6	-1.1
Smoking status: Current	1.7	2.7	5.5	-1.8	-1.3	-1.8	-1.5	-2.3	-0.7	-1.2	-1.7	-1.7	-1.2	-1.7	-2.0	-1.8	-1.8	-2.0	-1.7	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	6.9	1.4	1.2	2.6	1.7	1.0	1.1	1.6	0.9	1.0	1.2	1.0	0.8	1.6	1.2	-0.4	1.3	-2.0
Whole body water mass	1.0	6.0	11.6	-2.0	-2.8	-2.0	-2.8	-2.1	-2.6	-2.5	-2.7	-2.5	-2.5	-2.4	-2.0	-3.0	-2.7	0.2	-1.8	3.4
Leg predicted mass (right)	1.5	7.9	11.8	-2.4	-3.3	-2.2	-3.2	-2.3	-3.1	-3.0	-3.2	-2.9	-3.0	-2.8	-2.4	-3.4	-3.2	-0.1	-2.2	3.4
Arm fat mass (left)	1.1	4.6	9.2	-1.9	-2.4	-1.4	-3.0	-1.2	-1.6	-2.6	-2.3	-2.1	-2.1	-1.9	-1.5	-2.8	-2.3	1.4	-1.5	3.0
Number of self-reported non-cancer illnesses	0.6	1.1	2.7	1.1	1.0	1.0	0.1	1.6	1.5	0.4	0.9	0.9	1.5	1.0	1.1	0.2	0.6	0.5	1.6	-1.1
Average weekly champagne plus white wine intake	3.1	4.2	8.1	-1.8	-2.2	-1.1	-1.3	-1.7	-2.9	-2.3	-2.2	-2.4	-1.2	-2.5	-2.5	-2.5	-2.2	-1.4	-2.3	1.4
Miserableness	0.7	1.1	4.6	-0.7	-1.3	-1.0	-1.0	-0.3	-0.8	-1.3	-1.3	-0.9	-2.1	-0.9	-0.8	-1.5	-1.1	-0.5	-0.6	0.1
Guilty feelings	1.9	2.9	4.0	-1.5	-2.0	-1.9	-1.9	-1.7	-1.6	-1.6	-1.7	-1.8	-1.5	-1.8	-1.8	-1.6	-1.8	-0.8	-1.8	1.6
Wears glasses or contact lenses	1.7	2.0	5.1	0.9	1.1	1.1	1.9	2.3	-0.0	1.6	1.6	1.6	0.9	1.5	1.4	1.3	1.5	-0.3	1.0	-2.1
Ever taken oral contraceptive pill	1.2	1.4	3.7	-1.4	-0.8	-1.9	-0.9	-1.1	-0.0	-0.9	-1.3	-1.0	-1.5	-0.9	-1.1	-1.3	-1.1	-0.6	-1.5	1.4
Hearing aid user	1.1	1.3	5.2	0.8	1.6	1.2	0.8	0.8	1.7	0.8	1.2	0.9	2.3	0.9	0.7	0.7	1.0	1.2	0.4	-0.5
Mother’s age at death	0.5	0.6	1.2	0.5	1.0	1.1	0.8	0.8	0.7	0.8	0.7	0.7	0.2	0.7	0.9	1.1	0.7	0.1	1.0	-0.8
Financial situation satisfaction	0.7	0.9	3.2	-0.6	-0.9	-0.4	-1.6	-1.8	-0.0	-0.2	-1.0	-0.4	-1.5	-0.4	-0.7	-0.7	-0.9	-0.8	-0.4	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.7	-0.9	-0.8	-0.5	-1.1	-0.6	-0.4	-1.0	-1.2	-1.0	-0.7	-0.9	-0.9	-1.1	-1.1	0.5	-0.6	1.6
Commuting to job workplace: Public transport	1.8	2.1	6.1	1.9	1.7	1.1	1.4	0.7	1.2	1.6	1.8	1.6	2.5	1.6	1.4	0.4	1.6	0.2	1.3	-0.7
Eye problems/disorders: Glaucoma	0.3	0.3	1.5	-0.2	-0.4	-0.7	0.3	0.5	-1.2	-0.9	-0.3	-0.6	1.0	-0.6	-0.1	-0.5	-0.4	-0.4	-0.2	0.2
Medication: Blood pressure	1.9	3.6	5.9	1.9	2.0	0.7	1.5	2.4	1.8	1.4	2.1	2.0	1.9	2.1	2.4	2.2	2.1	0.9	2.4	-1.4
Pain type(s) experienced in last month: Hip pain	1.1	1.3	3.3	-0.8	-0.7	-1.3	-1.7	-1.2	-0.2	-1.4	-1.1	-1.4	-0.1	-1.3	-0.7	-1.3	-1.3	0.5	-0.9	1.8
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.9	-0.9	-0.6	-0.6	-0.8	-1.7	-0.1	-0.3	-0.7	-0.8	-0.6	-0.8	-0.9	-0.4	-0.8	-1.4	-0.9	0.2
High cholesterol (Self-reported)	3.7	6.5	10.0	2.3	2.6	3.0	1.6	2.9	2.9	2.9	2.6	3.2	1.5	3.1	2.7	2.2	2.6	1.4	3.0	-1.7
Medication: Bendroflumethiazide	0.9	1.4	4.3	0.5	1.2	0.4	0.2	1.6	2.1	1.1	1.2	1.3	1.1	1.4	1.6	1.1	1.1	1.3	0.8	-0.3
Medication: Paracetamol	0.9	1.4	3.6	-0.8	-1.7	-0.2	-1.9	-1.9	-1.1	-0.5	-1.1	-0.7	-1.9	-0.7	-0.8	-1.3	-1.1	-0.2	-0.8	1.2
Medication: Lisinopril	0.2	0.3	1.1	0.5	-0.1	0.6	0.0	1.1	-0.4	0.0	0.6	0.5	0.9	0.6	0.7	0.1	0.4	0.3	0.7	-0.4
Medication: Atorvastatin	0.6	0.7	6.2	0.2	0.7	0.3	0.3	1.5	1.0	0.2	0.5	0.3	0.7	0.3	0.4	0.6	0.4	2.5	0.5	-0.3
Illnesses of father: High blood pressure	1.7	2.1	4.5	1.3	1.6	-0.2	1.1	1.3	2.1	1.0	1.7	1.3	2.0	1.3	1.4	1.8	1.6	1.8	0.8	-1.0
Alcohol drinker status: Never	0.6	0.7	1.6	-0.6	-0.8	-0.3	-0.6	-1.1	-1.1	-0.9	-0.8	-0.9	-0.9	-0.9	-0.9	-0.9	-0.8	-1.3	-0.4	0.4
Ever smoked	0.2	0.3	0.9	-0.8	0.4	-0.5	-0.2	-0.2	0.9	-0.3	-0.5	-0.6	-0.8	-0.7	-0.6	-0.2	-0.5	0.1	-0.9	0.1
Basal metabolic rate	1.0	5.4	10.8	-1.9	-2.6	-2.0	-2.8	-1.9	-2.4	-2.3	-2.6	-2.3	-2.3	-2.2	-1.8	-3.0	-2.6	0.3	-1.6	3.3
Leg fat percentage (left)	0.1	0.5	2.0	-0.5	-0.5	-0.4	-1.1	0.0	0.0	-0.9	-0.7	-0.5	-0.5	-0.3	-0.0	-1.1	-0.6	1.1	0.0	1.4
Arm fat-free mass (left)	1.1	5.5	11.0	-2.0	-2.5	-2.5	-2.6	-2.1	-2.4	-2.2	-2.5	-2.4	-2.4	-2.2	-1.7	-2.9	-2.5	-0.2	-1.7	3.3
Number of operations (self-reported)	0.7	1.1	2.2	0.7	1.0	1.0	0.8	0.7	0.8	1.2	1.2	1.3	0.5	1.3	1.5	0.9	1.2	-0.2	1.1	-1.3
Average weekly beer plus cider intake	1.0	1.4	3.1	0.7	1.6	0.8	0.8	1.3	1.8	1.2	1.1	1.3	1.4	1.3	1.0	0.9	1.1	1.7	0.8	-0.2
Irritability	0.8	1.3	4.4	-0.9	-0.9	-1.5	-0.7	-0.8	-0.4	-1.3	-0.7	-1.0	-0.3	-1.1	-1.2	-2.1	-1.0	-2.0	-1.3	0.3
Risk taking	0.2	0.3	2.1	-0.1	-0.0	0.6	-0.5	0.3	0.2	0.5	-0.3	0.4	-0.5	0.5	0.0	-0.6	-0.1	1.1	0.2	1.5
Ever had prostate specific antigen (PSA) test	0.3	0.3	3.2	-0.3	0.1	-0.3	0.4	-0.2	-0.1	0.7	0.4	0.2	-0.4	0.4	0.5	-0.5	0.3	-1.8	0.1	-0.6
Fractured/broken bones in last 5 years	0.7	0.8	2.1	1.1	1.0	-0.2	0.7	0.3	1.0	1.0	0.8	1.0	1.2	1.0	0.9	1.4	0.9	-0.2	1.0	-0.8
Age started oral contraceptive pill	0.8	1.1	2.6	-0.6	-0.9	0.3	-0.4	-0.9	-1.1	-1.6	-1.1	-1.3	-1.0	-1.5	-1.6	-0.8	-0.9	-0.9	-0.9	0.0
Diastolic blood pressure, automated reading	11.9	37.0	49.0	6.5	6.5	2.7	5.7	6.7	6.0	6.1	7.0	6.7	6.9	6.8	6.9	5.7	6.7	3.0	6.7	-4.5
Ever depressed for a whole week	2.8	3.5	5.8	-1.6	-2.2	0.2	-1.9	-2.4	-1.7	-1.8	-2.2	-2.0	-1.5	-2.0	-2.0	-2.1	-2.1	-0.5	-1.8	2.0
Unable to work because of sickness or disability	0.3	0.3	1.6	0.3	0.3	1.3	0.4	0.5	0.1	0.7	0.4	0.9	0.3	0.8	0.4	-0.8	0.5	-0.3	0.3	-0.1
Commuting to job workplace: Cycle	1.6	2.0	5.3	-1.1	-2.0	-0.6	-1.9	-2.3	-1.7	-0.8	-1.4	-1.1	-1.8	-1.1	-1.3	-0.7	-1.5	-0.6	-1.1	1.3
Myopia	3.4	4.9	8.3	-2.1	-2.9	-1.9	-2.5	-1.8	-2.9	-2.5	-2.5	-2.3	-2.3	-2.2	-2.0	-2.2	-2.5	-0.3	-1.8	1.7
Vascular/heart problems diagnosed by doctor	1.6	4.3	11.7	-1.8	-2.0	-0.5	-1.5	-3.4	-1.9	-1.2	-2.2	-2.1	-2.7	-2.2	-2.3	-1.8	-1.9	-2.4	-2.0	1.5
Cholesterol lowering medication	0.1	0.2	0.6	0.4	-0.1	0.7	-0.4	0.1	-0.1	0.4	0.4	0.5	0.5	0.6	0.4	-0.4	0.1	-0.6	0.6	0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.6	-0.1	-1.0	0.7	-0.5	-1.6	-1.2	-0.4	-0.8	-0.6	-0.5	-0.6	-0.8	0.4	-0.8	-1.1	0.1	-0.9
Pain experienced in last month	0.8	1.3	2.7	-0.5	-1.6	1.0	-1.4	-1.1	-1.4	-0.5	-1.5	-0.5	-1.3	-0.6	-1.1	-1.4	-1.2	0.5	-1.0	1.6
Supplements: Calcium	0.6	0.6	1.9	-0.5	-0.1	1.1	-0.2	-1.4	-0.2	-0.7	-0.5	-1.0	-0.5	-1.1	-1.3	-0.4	-0.5	-1.0	-0.9	-0.2
Basal cell carcinoma (self-reported)	3.4	4.1	7.9	-1.6	-2.5	-1.8	-2.2	-2.1	-2.8	-2.0	-2.1	-1.7	-2.3	-1.7	-1.9	-2.1	-2.2	-1.2	-1.3	2.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.1	-0.5	0.6	-0.9	0.8	1.1	0.3	0.1	0.5	0.0	0.6	0.1	0.5	-0.5	0.4	-0.0	-0.4	0.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.8	0.9	0.7	1.4	0.4	0.6	0.8	0.2	0.7	0.5	0.6	0.6	0.8	-0.4	0.6	-0.5	1.3	-1.2
Heart disease (siblings)	2.0	2.4	4.6	-1.4	-1.4	0.2	-1.4	-1.6	-1.5	-2.1	-1.6	-2.0	-0.4	-1.9	-1.5	-1.9	-1.7	-0.1	-1.5	1.9
Alcohol drinker status: Previous	0.2	0.2	1.2	0.3	-0.1	0.3	0.2	-0.0	-0.1	0.8	0.1	0.6	-0.2	0.7	0.5	0.1	0.3	0.2	0.8	1.1
Pack years of smoking	0.3	0.4	1.3	0.8	0.4	0.5	1.1	1.1	-0.5	0.4	0.6	0.4	0.8	0.4	0.6	0.3	0.6	0.3	0.7	-0.6
Impedance of whole body	1.6	8.2	11.8	2.5	3.0	2.1	3.4	3.0	2.6	3.4	3.2	3.3	2.5	3.2	2.7	3.0	3.2	-0.2	2.6	-3.4
Leg fat mass (left)	0.5	2.0	6.3	-1.2	-1.4	-1.2	-2.0	-0.7	-0.8	-1.6	-1.5	-1.3	-1.3	-1.1	-0.7	-1.8	-1.5	1.4	-0.8	2.5
Arm predicted mass (left)	0.9	4.8	9.7	-1.9	-2.3	-2.5	-2.4	-1.9	-2.3	-2.1	-2.4	-2.2	-2.2	-2.1	-1.6	-2.7	-2.3	-0.1	-1.5	3.1