[Hub]/) : Traits : Heel T-Score : ← →

chr2:111,957,073-114,040,741

Best TWAS P=1.99e-16 · Best GWAS P=6.34e-12 conditioned to 0.00363

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FBLN7	0.21	0.09	lasso	18	0.20	2.2e-24	3.9	6.3	2.8e-10	0.25	0.97	0.03	FALSE
2	GTEx	Artery Aorta	MERTK	0.15	0.10	lasso	3	0.08	5.6e-05	6.5	5.6	2.6e-08	0.66	0.10	0.66	FALSE
3	GTEx	Artery Coronary	CHCHD5	0.13	0.03	lasso	4	0.00	2.8e-01	-6.6	5.8	5.4e-09	0.06	0.05	0.63	FALSE
4	GTEx	Artery Tibial	FBLN7	0.48	0.37	enet	7	0.38	3.3e-31	-5.1	-5.9	4.1e-09	-0.22	1.00	0.00	FALSE
5	GTEx	Artery Tibial	TMEM87B	0.12	0.08	lasso	9	0.07	5.5e-06	5.6	5.2	2.0e-07	0.15	0.84	0.15	FALSE
6	GTEx	Brain Cortex	FBLN7	0.25	0.00	lasso	11	0.00	2.6e-01	3.9	6.1	1.4e-09	0.32	0.06	0.10	FALSE
7	GTEx	Cells Transformed fibroblasts	MERTK	0.18	0.04	lasso	9	0.03	3.3e-03	6.5	7.4	1.1e-13	0.60	0.10	0.55	FALSE
8	GTEx	Colon Sigmoid	MERTK	0.47	0.07	lasso	10	0.20	1.9e-07	6.5	8.2	2.0e-16	0.54	0.10	0.86	TRUE
9	GTEx	Esophagus Mucosa	MERTK	0.21	0.05	lasso	6	0.05	1.6e-04	6.5	6.5	9.3e-11	0.68	0.12	0.84	FALSE
10	GTEx	Esophagus Muscularis	MERTK	0.49	0.12	enet	40	0.11	3.4e-07	6.5	6.5	6.5e-11	0.33	0.11	0.85	FALSE
11	GTEx	Lung	MERTK	0.34	0.07	lasso	6	0.05	1.2e-04	6.5	6.4	1.5e-10	0.72	0.10	0.68	FALSE
12	GTEx	Muscle Skeletal	MERTK	0.26	0.05	lasso	7	0.04	4.3e-05	5.0	7.0	3.5e-12	0.32	0.45	0.37	FALSE
13	GTEx	Muscle Skeletal	TMEM87B	0.04	0.01	enet	9	0.01	5.3e-02	-6.7	-5.6	2.0e-08	0.00	0.07	0.80	FALSE
14	GTEx	Pancreas	MERTK	0.31	0.34	enet	13	0.38	3.4e-17	-5.6	-5.6	2.3e-08	-0.02	0.17	0.83	FALSE
15	GTEx	Skin Sun Exposed Lower leg	MERTK	0.33	0.08	enet	48	0.11	3.7e-09	6.5	5.8	6.5e-09	0.05	0.11	0.85	FALSE
16	GTEx	Thyroid	FBLN7	0.50	0.19	lasso	8	0.31	1.5e-24	3.9	-5.8	6.4e-09	-0.27	0.97	0.03	FALSE
17	GTEx	Thyroid	TMEM87B	0.09	0.00	lasso	5	0.01	1.1e-01	-5.7	-7.2	7.5e-13	-0.15	0.08	0.36	FALSE
18	GTEx	Vagina	FBLN7	0.39	0.05	lasso	11	0.07	1.1e-02	5.0	-5.9	3.8e-09	-0.55	0.05	0.50	FALSE
19	METSIM	Adipose	FBLN7	0.14	0.03	enet	20	0.08	4.1e-12	-5.1	-6.2	4.7e-10	-0.40	0.96	0.04	FALSE
20	METSIM	Adipose	TMEM87B	0.05	0.01	bslmm	353	0.03	6.6e-05	-6.6	-7.8	4.4e-15	-0.16	0.07	0.83	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	FBLN7	0.32	0.09	enet	41	0.26	1.3e-32	-5.7	5.9	3.6e-09	0.17	0.92	0.08	FALSE
22	The Cancer Genome Atlas	Glioblastoma Multiforme	MERTK	0.31	0.15	lasso	2	0.15	3.4e-05	4.5	5.7	1.6e-08	0.52	0.04	0.22	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MERTK	0.27	0.02	blup	114	0.05	1.3e-03	6.5	7.1	1.5e-12	0.74	0.04	0.34	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	MERTK	0.18	0.19	lasso	3	0.19	9.5e-20	-5.6	-5.7	1.0e-08	-0.05	0.17	0.83	FALSE