Hub : Genes

TMEM87B

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2130	0.0490	7.2e-15	0.170	0.144	0.174	0.088	0.088	3.0e-20	4.1e-17	1.1e-20	8.3e-11	8.0e-11
2	GTEx	Adipose Visceral Omentum	0.1380	0.0520	2.8e-04	0.000	NA	0.018	NA	0.019	3.2e-01	NA	3.8e-02	NA	3.6e-02
3	GTEx	Artery Aorta	0.1270	0.0570	9.8e-04	0.001	NA	0.014	NA	0.010	2.8e-01	NA	5.2e-02	NA	8.5e-02
4	GTEx	Artery Tibial	0.1186	0.0443	3.7e-05	0.081	NA	0.060	NA	0.067	6.4e-07	NA	1.8e-05	NA	5.5e-06
5	GTEx	Cells Transformed fibroblasts	0.1450	0.0430	3.4e-09	0.161	NA	0.184	NA	0.166	4.1e-12	NA	9.3e-14	NA	1.9e-12
6	GTEx	Muscle Skeletal	0.0382	0.0193	8.6e-03	0.012	NA	0.008	NA	0.005	2.0e-02	NA	5.3e-02	NA	9.5e-02
7	GTEx	Nerve Tibial	0.1351	0.0415	5.0e-07	0.037	NA	0.069	NA	0.055	1.2e-03	NA	1.3e-05	NA	8.7e-05
8	GTEx	Pancreas	0.2900	0.0830	2.8e-05	0.039	NA	0.069	NA	0.081	9.3e-03	NA	7.2e-04	NA	2.6e-04
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1250	0.0530	1.5e-03	0.080	NA	0.066	NA	0.051	3.8e-05	NA	1.8e-04	NA	8.6e-04
10	GTEx	Thyroid	0.0880	0.0450	7.1e-03	-0.002	NA	-0.001	NA	0.006	5.7e-01	NA	3.9e-01	NA	1.1e-01
11	GTEx	Whole Blood	0.0870	0.0330	4.5e-04	0.012	NA	0.016	NA	0.008	2.5e-02	NA	1.1e-02	NA	5.1e-02
12	METSIM	Adipose	0.0453	0.0254	4.6e-03	0.005	0.020	0.019	0.026	0.013	4.9e-02	4.1e-04	5.3e-04	6.6e-05	3.5e-03
13	ROSMAP	Brain Pre-frontal Cortex	0.1755	0.0456	1.0e-09	0.031	0.096	0.089	0.095	0.088	6.8e-05	2.5e-12	1.8e-11	3.5e-12	2.1e-11
14	TCGA	Bladder Urothelial Carcinoma	0.0670	0.0390	2.8e-03	0.016	0.010	0.014	NA	0.008	1.5e-02	4.6e-02	2.1e-02	NA	6.8e-02
15	TCGA	Breast Invasive Carcinoma	0.0315	0.0183	3.2e-03	0.007	0.006	0.000	NA	0.001	1.2e-02	1.8e-02	2.8e-01	NA	2.0e-01
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0271	0.0144	1.4e-03	0.044	0.021	0.031	NA	0.035	1.1e-05	1.8e-03	1.7e-04	NA	8.0e-05
17	TCGA	Pancreatic Adenocarcinoma	0.0910	0.0480	4.6e-03	0.044	0.074	0.025	NA	0.040	6.1e-03	4.8e-04	3.0e-02	NA	8.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.9	1.4	4.7	-1.9	0.8	-0.8	-1.5	0.3	1.1	1.1	2.0	0.3	1.1	-2.2	0.6	0.5	-0.4	-0.3	-1.7	-0.4
Bipolar Disorder or Schizophrenia	0.6	1.5	4.7	-1.1	1.9	1.4	-2.2	1.8	0.0	-0.2	0.8	-1.4	0.4	-1.3	-1.0	-0.5	1.1	1.5	-0.7	1.1
Depressed Affect (Nagel 2018)	0.7	1.5	5.8	1.1	-0.6	-0.2	1.4	-0.1	-1.5	-1.6	-1.8	-1.7	-1.6	1.0	-2.4	-0.6	0.7	-0.1	1.1	0.5
Depression (Nagel 2018)	0.5	0.8	3.4	0.6	-0.4	-0.1	0.2	-0.3	-0.6	-1.2	-1.3	-0.8	-1.8	0.2	-1.9	-0.4	-0.3	-0.7	0.8	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.9	-0.0	-1.4	-0.4	1.0	-0.7	-0.1	-0.3	-0.4	-0.2	0.2	-0.4	0.2	-1.2	0.6	-0.7	-0.2	0.4
Neuroticism (Nagel 2018)	0.8	1.8	5.2	2.3	1.0	1.1	-0.4	1.2	-0.9	-1.5	-1.3	-1.3	-0.9	0.8	-2.0	0.8	1.0	1.0	1.7	2.1
Schizophrenia (2018)	1.1	2.2	6.3	0.1	1.8	2.5	-1.5	2.1	-0.9	-1.2	-0.5	-2.1	-0.4	0.1	-1.8	-1.0	1.6	2.1	0.5	1.8
Schizophrenia vs Biploar Disorder	2.0	2.7	7.2	1.4	-0.8	0.9	0.8	0.4	-2.0	-2.2	-2.2	-1.8	-2.7	1.9	-2.1	-2.0	0.1	0.0	2.3	0.7
Worry (Nagel 2018)	0.4	0.7	3.1	1.4	1.0	0.8	-1.1	0.9	0.4	-0.6	-0.2	0.2	0.4	0.2	0.5	1.2	0.4	0.9	0.8	1.8
Alzheimer’s Disease (in mother)	0.1	0.2	1.1	0.3	0.1	1.0	0.2	-0.1	-0.0	-0.2	-0.3	-0.1	0.3	-0.4	0.4	0.6	-0.5	-0.2	0.4	0.4
Alzheimer’s Disease (in father)	0.8	0.8	2.0	-0.7	0.7	0.7	-0.2	-0.3	1.4	1.3	1.0	1.2	0.8	-0.7	1.2	1.2	0.0	0.4	-1.3	-0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	1.0	0.1	-0.6	0.8	1.0	-0.8	0.1	-0.4	-0.6	-0.1	-0.1	-0.4	0.6	0.4	-0.5	-0.5	0.2	-0.3
Crohns Disease (2017)	1.9	4.2	10.7	-3.2	1.3	-1.0	-1.6	-1.0	2.8	2.6	2.4	1.9	1.7	-2.2	1.8	-0.3	-1.3	-1.1	-3.3	-2.6
Irritable Bowel Disease (IBD)	1.2	2.8	7.6	-2.8	1.4	-0.5	-1.6	-0.3	2.2	2.3	2.4	1.5	1.4	-1.4	0.7	-0.2	-0.6	-0.4	-2.8	-2.1
Ulcerative Colitis (UC)	0.5	0.9	3.2	-1.5	0.9	0.0	-1.2	0.5	0.9	1.2	1.8	0.6	0.5	-0.6	-0.7	-0.1	0.2	0.4	-1.4	-0.8
Major Depression (MDD)	0.3	0.4	1.3	-0.1	-0.5	-0.2	0.8	-0.1	-0.5	-0.8	-1.1	-1.0	-0.9	-0.2	-0.7	0.3	0.2	-0.2	0.9	0.5
Reaction Time	1.9	3.6	11.8	-0.5	-3.4	-2.7	2.0	-2.9	0.9	-0.4	-0.7	-0.0	0.5	-2.0	3.1	-2.6	-1.2	-2.2	0.1	-0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.4	2.1	-0.7	-1.0	-0.3	0.7	-0.8	0.4	0.0	-0.2	-0.0	-0.6	-0.3	0.1	-1.4	-0.1	-1.1	-0.4	-0.5
Breast Cancer	0.4	1.0	4.9	0.7	0.8	0.6	0.6	0.8	-0.8	1.0	0.7	0.8	-0.1	2.2	-1.1	1.2	1.1	1.8	-0.6	-0.5
Ovarian Cancer	1.4	1.8	4.1	1.6	1.0	0.6	0.2	1.7	-1.5	-2.0	-1.5	-1.8	-0.4	0.6	-0.9	1.2	1.8	1.5	0.6	2.0
Prostate Cancer	1.4	2.0	5.4	-0.0	1.7	2.3	-1.6	2.2	-0.8	0.5	1.6	-0.9	0.7	0.6	-1.2	0.1	1.6	2.1	0.3	1.8
Age at First Birth	0.7	1.0	3.3	-0.6	-1.4	-0.4	-0.1	-1.6	1.1	1.3	0.8	1.8	0.9	-0.4	1.0	-0.1	-0.2	-1.1	-0.8	-0.8
Bipolar Disorder (2011)	0.2	0.2	1.1	0.5	0.1	0.0	-0.3	-0.0	0.3	-0.1	-0.4	0.5	0.3	-0.1	0.2	0.9	0.4	0.1	0.4	1.1
Body Mass Index (BMI) (2010)	0.3	0.4	1.1	-0.5	0.6	-0.0	0.2	0.7	-0.2	0.8	1.0	0.3	0.5	0.3	-0.2	0.6	0.9	0.9	-0.8	-0.9
Coronary Artery Disease (CAD)	0.8	0.9	2.2	-1.3	0.2	-1.2	-0.4	-0.6	1.0	1.0	1.2	1.0	0.3	-1.2	1.0	-0.4	-1.4	-0.5	-1.0	-1.5
Crohns Disease (2012)	0.7	1.1	4.2	-1.7	1.1	-0.4	-1.0	-0.1	1.1	1.4	1.1	0.5	0.6	-0.8	0.5	-0.0	-0.9	-0.0	-2.1	-1.5
Mean Putamen Volume	1.3	1.4	3.8	0.9	1.1	0.8	0.2	1.7	-1.2	-1.1	0.0	-1.8	0.1	0.3	-1.2	-0.9	1.9	1.9	0.4	1.8
Fasting Glucose	1.7	2.0	7.1	-0.9	-0.0	-0.7	-0.8	-1.6	1.7	1.9	0.9	2.7	1.3	-0.7	1.5	1.1	-1.7	-2.0	-1.3	-1.0
HbA1C	0.7	0.8	2.4	1.1	-0.6	-0.2	0.1	0.6	-1.1	-1.5	-0.6	-1.3	-0.7	-0.0	-0.5	-0.5	0.7	0.7	1.5	1.2
HDL Cholesterol	0.2	0.3	1.1	0.1	1.1	0.4	-0.9	0.4	0.2	0.4	0.7	0.5	0.1	0.3	0.1	0.6	0.2	0.9	-0.0	-0.1
LDL Cholesterol	0.6	0.9	4.5	-0.8	-0.3	-0.6	-0.6	-1.6	1.3	1.3	0.6	2.1	0.2	0.1	1.0	0.7	-0.5	-1.3	-0.4	-0.6
Lupus	0.9	1.4	4.7	1.2	-0.6	0.4	0.5	0.1	-0.8	-2.2	-1.5	-2.2	-1.7	0.7	-0.4	-0.8	1.2	1.2	1.2	0.6
Neuroticism (2016)	1.2	1.7	3.8	0.9	-1.6	-0.9	1.1	-0.6	-0.7	-1.8	-1.9	-1.5	-1.8	-0.3	-1.1	-1.6	-1.8	-1.4	1.3	0.1
Primary Biliary Cirrhosis	0.6	0.8	6.9	-0.2	0.8	2.6	-0.3	0.6	0.8	0.1	0.1	-0.7	-1.1	0.7	-0.6	-1.0	0.3	1.1	0.5	-0.1
Rheumatoid Arthritis	0.7	1.0	3.1	-0.1	0.9	0.2	-1.1	1.8	-1.3	-0.8	0.1	-1.8	-0.3	-0.4	-1.5	-1.5	0.2	0.9	0.3	0.7
Schizophrenia (2014)	1.7	3.8	10.6	0.0	1.6	2.7	-1.6	2.7	-1.9	-2.0	-0.7	-2.9	-1.7	0.2	-3.2	-1.8	1.5	2.1	1.1	1.9
Triglycerides	0.4	0.6	1.6	-0.2	1.0	1.2	-1.1	1.3	-0.3	-0.1	0.3	-0.6	-0.3	0.2	-1.2	-1.0	0.1	1.2	0.0	0.5
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.3	0.3	1.5	1.1	-0.5	1.2	-0.8	-0.4	-0.2	-0.7	0.2	0.3	-0.7	-0.3	0.8	1.2	0.8	1.4
Ulcerative Colitis	0.3	0.4	1.3	-1.1	0.7	-0.6	-0.8	0.4	0.5	0.6	1.0	0.4	0.3	-0.6	-0.2	-0.5	0.0	0.5	-0.9	-0.7
Blood Eosinophil Count	0.2	1.3	7.5	-0.7	-0.8	-2.0	1.1	-0.9	-2.7	-0.2	-1.1	-0.4	-0.1	-0.1	-2.2	-0.4	0.5	-0.6	0.4	0.6
Blood Platelet Count	0.5	6.2	18.5	2.4	-1.4	1.2	2.6	0.7	-4.3	-2.6	-3.0	-3.0	-3.2	2.9	-3.0	0.3	2.1	1.9	3.0	0.9
Blood Red Count	1.7	16.8	54.1	-4.8	3.4	1.4	-5.4	-0.7	7.4	5.4	6.0	4.1	4.2	-4.3	2.7	-0.2	-2.6	-1.7	-5.0	-2.3
Blood White Count	4.9	36.5	82.4	-6.6	2.1	-2.5	-6.0	-4.2	8.3	9.1	6.9	8.5	7.2	-5.8	5.6	5.5	-4.2	-4.6	-6.6	-3.5
Heel T-Score	2.1	16.8	61.5	2.0	-3.3	0.9	5.2	1.0	-5.6	-4.2	-3.4	-4.8	-7.2	4.8	-7.8	-1.6	1.6	1.5	3.4	-1.5
BMI	0.3	1.9	8.5	-1.7	2.9	1.8	-2.2	0.6	1.5	1.3	1.6	0.1	0.5	-1.5	-0.2	1.3	-0.3	-0.4	-0.8	-0.4
Height	0.2	4.8	18.2	2.7	-2.1	-0.6	4.3	-0.6	-1.6	-3.9	-4.0	-2.8	-1.6	0.9	-0.1	-0.3	1.5	0.2	1.5	1.4
Waist Hip Ratio (WHR)	0.2	1.0	5.5	-1.7	0.8	-0.2	-1.6	0.2	1.0	0.8	1.4	0.2	0.5	-2.3	0.5	0.0	-0.6	-0.6	-0.9	0.0
Systolic Blood Pressure	3.4	16.9	34.7	-3.8	4.1	-0.1	-5.9	0.2	5.5	5.2	5.1	4.6	5.8	-4.5	4.0	3.7	-1.6	-0.7	-5.3	-0.7
Smoking Status	0.5	1.3	6.2	-0.4	2.5	2.3	-1.3	1.7	0.0	0.4	-0.0	0.1	-0.2	0.3	-1.1	0.7	0.0	1.4	0.5	1.1
Allergy or Eczema	0.5	1.3	4.9	1.1	0.0	-0.5	-0.5	0.6	-2.2	-1.0	-0.9	-0.5	-0.5	1.4	-1.4	-0.7	1.3	1.3	1.5	1.4
Cardiovascular Disease	3.1	10.2	23.3	-3.7	3.5	0.8	-4.8	0.7	4.2	3.9	3.6	3.2	3.8	-4.0	2.0	3.4	-0.4	-0.1	-4.6	-0.4
Hypothyroidism (self reported)	0.3	0.8	3.1	-0.4	1.4	1.2	-1.3	-0.4	1.0	1.5	0.3	0.7	0.6	-0.2	-0.8	1.8	0.3	-0.1	-0.1	0.4
Respiratory disease	0.3	0.6	3.0	0.7	-0.6	-0.3	0.1	0.0	-0.7	-0.5	-0.5	0.0	0.7	-0.1	-0.1	0.1	1.7	0.9	0.6	1.7
Type 2 Diabetes (T2D) (2018)	4.4	8.2	20.5	-3.5	2.7	-0.2	-3.4	0.3	3.2	3.9	4.2	3.0	3.8	-3.3	1.6	1.8	-0.7	-0.4	-4.5	-1.4
Lung FEV1/FVC ratio	0.5	2.3	10.6	0.2	-2.6	-0.8	1.8	-2.3	0.2	-0.2	-0.6	0.5	-2.4	1.2	0.6	0.7	-1.4	-1.7	-0.3	-3.2
Lung FVC	1.0	5.3	10.2	2.3	-2.4	-1.8	2.9	-0.6	-3.1	-3.0	-3.2	-2.6	-3.0	1.8	-2.4	-2.7	-0.6	-0.0	2.5	0.1
Neuroticism	0.3	0.8	2.1	1.3	0.2	1.0	-0.1	0.9	-0.4	-1.1	-0.7	-0.9	-0.9	0.8	-1.5	-0.0	0.5	0.6	0.9	1.3
Chronotype (morning person)	1.9	4.4	11.4	-2.5	1.6	-0.6	-2.4	-1.5	3.4	3.2	2.3	2.6	1.9	-1.7	1.5	0.6	-2.1	-1.9	-1.6	-1.8
Hair Pigment	0.0	0.7	2.1	-1.1	0.9	0.5	-1.0	0.9	-0.1	-0.2	1.1	-0.4	0.7	-1.4	-0.3	-1.1	0.8	0.2	-0.4	1.1
Tanning	0.0	0.5	1.7	0.4	-0.7	-0.4	1.1	-0.6	-0.7	-0.3	-1.2	0.5	-0.9	1.3	-0.8	0.3	-0.6	-0.3	0.8	-0.3
Hand grip strength (left)	0.4	1.1	4.8	-1.0	0.7	0.6	-1.2	0.7	0.1	0.0	0.7	-1.2	1.8	-1.8	0.0	-1.2	0.2	0.0	-0.1	2.2
Number of treatments/medications taken	0.8	1.5	8.6	0.1	1.9	0.8	-1.4	0.9	0.9	0.9	0.8	1.2	1.3	-0.4	1.0	2.9	0.9	0.9	-0.7	0.8
Average weekly spirits intake	0.6	0.7	2.4	0.9	0.5	-0.6	-0.8	-0.7	0.4	-0.0	-0.3	1.1	-0.9	0.8	0.0	0.8	-1.5	-1.5	1.0	-0.5
Sensitivity / hurt feelings	0.9	1.6	5.6	1.8	-1.0	0.6	1.0	0.2	-0.7	-1.8	-1.6	-1.2	-2.4	1.4	-1.8	-0.8	0.4	0.5	1.3	0.1
Frequency of depressed mood in last 2 weeks	0.8	1.1	4.2	1.1	-0.1	0.9	0.3	-0.1	-1.1	-1.2	-1.7	-0.8	-2.0	1.2	-1.9	0.2	0.3	-0.0	1.2	0.5
Hearing difficulty/problems: Yes	1.2	1.9	6.6	0.0	2.4	2.6	-1.8	1.9	0.9	1.1	1.7	0.5	0.8	0.0	-0.8	0.3	0.9	1.8	-1.1	0.7
Relative age of first facial hair	0.8	1.6	6.1	2.4	-0.7	0.0	0.9	-0.1	-1.0	-0.9	-1.7	0.6	-0.4	2.5	0.7	1.3	1.3	1.1	1.5	1.1
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	6.2	0.6	2.5	2.1	-2.0	1.8	0.4	0.6	0.9	-0.1	0.3	0.1	-1.3	2.0	0.8	1.0	-0.1	1.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.9	0.9	0.7	0.0	-0.9	0.5	-0.4	-0.8	0.0	-0.1	-0.5	-0.1	0.2	0.5	0.1	0.2	0.7	0.4
Ever had hysterectomy (womb removed)	0.7	0.8	2.7	0.6	0.7	-0.2	-1.6	1.3	-0.4	-0.6	0.0	-1.3	-0.3	-0.3	-1.3	0.5	0.2	0.0	1.0	1.6
Systolic blood pressure, automated reading	3.1	9.0	20.7	-2.4	3.7	-0.1	-4.5	0.7	4.0	3.6	3.9	3.0	4.6	-3.3	3.1	2.4	-0.8	-0.5	-3.5	0.1
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	9.7	-2.9	-0.4	-0.3	-1.4	-0.4	1.2	0.7	1.9	-0.4	0.8	-3.1	-0.1	-2.3	-1.3	-1.1	-2.0	-0.7
Angina	1.7	2.2	7.2	-0.5	-1.5	-1.9	0.5	-2.7	1.7	0.2	-0.6	2.4	0.4	-0.5	2.4	1.9	-0.8	-1.8	-0.8	-1.1
Medication for hormone replacement therapy	0.4	0.4	1.1	0.7	1.1	1.0	-0.8	0.8	0.7	-0.2	-0.0	-0.9	0.2	-0.1	0.4	0.3	0.3	0.8	0.5	0.7
Vitamin and mineral supplements	0.6	0.9	3.3	0.1	1.8	1.8	-1.3	0.9	-0.0	0.3	-0.1	0.0	-0.4	1.0	-1.3	1.0	0.7	0.6	0.5	0.6
Supplements: Zinc	0.8	0.9	3.4	0.1	1.3	1.6	-1.1	1.9	-0.1	0.3	1.0	-0.9	0.1	-0.1	-1.1	-0.4	0.5	1.2	0.2	0.9
Medication: Co-codamol	1.5	1.7	5.3	1.4	0.3	0.4	0.5	1.4	-1.9	-2.1	-1.1	-2.3	-0.3	0.2	-1.1	-0.1	1.6	1.2	1.2	1.9
Medication: Metformin	2.2	3.2	8.2	-2.8	1.3	-0.3	-2.2	0.3	1.6	2.5	2.9	1.9	2.1	-2.3	0.1	0.5	-0.8	-0.3	-2.8	-0.9
Diabetes (father)	0.9	1.1	5.6	-0.7	2.4	0.0	-2.2	0.9	0.8	0.6	0.7	-0.2	0.3	-0.5	-0.3	1.1	-1.2	0.1	-1.5	-0.4
Diabetes (mother)	0.5	0.6	2.2	-1.4	0.9	-0.1	-1.5	0.7	-0.0	0.6	1.0	-0.3	0.3	-1.0	-1.3	-0.3	-0.3	0.3	-0.7	-0.1
Severe depression (siblings)	0.6	0.6	3.3	-0.6	0.8	1.1	0.1	0.8	-0.4	-0.3	-0.2	-1.0	-1.5	0.1	-1.8	-0.0	-0.1	0.0	-0.8	-0.3
Pack years adult smoking proportion	0.8	1.3	4.9	-1.5	0.3	-0.5	-0.7	-0.7	1.6	0.6	0.6	1.1	1.7	-2.2	1.6	-0.8	-1.0	-1.1	-0.7	0.3
Impedance of leg (right)	0.8	3.8	12.9	-2.1	3.6	1.0	-3.5	2.4	1.3	2.2	3.0	0.2	1.5	-0.7	-1.4	0.1	-0.8	1.5	-2.0	0.3
Leg fat-free mass (left)	0.1	0.5	1.9	0.3	-0.3	0.3	1.3	-1.4	0.6	-0.5	-1.3	-0.1	-0.3	-0.1	0.8	0.8	-0.1	-0.9	0.2	-0.6
Trunk fat percentage	0.6	2.3	14.3	-0.8	3.8	1.7	-2.1	0.9	1.8	1.4	1.5	0.6	-0.3	0.2	-0.3	2.2	-0.8	0.3	-1.0	-1.2
Hand grip strength (right)	0.3	0.7	5.0	-0.5	-0.0	0.7	-0.3	0.7	-0.7	-0.4	0.0	-1.1	1.5	-0.9	-0.1	-0.9	0.7	0.1	0.1	2.2
Townsend deprivation index at recruitment	2.1	3.0	10.6	0.5	1.3	2.4	-0.7	2.7	-1.7	-1.5	-0.7	-3.2	-0.9	-0.1	-2.4	0.1	1.3	1.9	1.4	2.3
Current tobacco smoking	0.5	0.8	2.3	0.5	0.8	1.5	0.2	1.0	-0.3	-0.3	-0.6	0.1	-0.4	1.1	-1.2	0.8	1.3	1.3	0.8	0.9
Average weekly fortified wine intake	0.3	0.3	1.3	0.8	-0.1	-0.9	0.2	-0.5	-0.2	-0.8	-0.5	0.0	-0.3	0.2	1.0	0.5	-0.2	-0.4	1.1	0.3
Maternal smoking around birth	1.1	1.6	3.6	-1.6	1.9	0.7	-1.8	0.4	1.9	1.7	1.7	0.6	1.4	-1.3	0.1	0.3	-0.6	-0.7	-1.8	-0.2
Fed-up feelings	0.1	0.2	1.7	-0.0	0.0	-0.2	0.2	-0.4	0.1	-0.4	-0.7	-0.4	-0.5	0.3	-1.3	0.1	-0.1	-0.2	0.3	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.2	1.1	0.4	0.6	-1.2	-0.4	0.0	0.1	-0.8	0.8	-0.6	0.5	-1.4	1.5	-0.5	-0.3	0.8	0.7
Relative age voice broke	0.4	0.6	1.3	0.7	-0.7	-0.7	0.5	-1.1	0.2	-0.3	-1.0	0.9	-0.8	1.0	1.0	0.8	-0.3	-0.7	1.0	-0.1
Taking other prescription medications	1.2	1.8	4.4	0.7	2.1	1.9	-1.6	2.0	-0.3	-0.1	0.4	-0.2	0.9	-0.0	-0.9	2.0	1.7	1.7	-0.1	2.1
Age when periods started (menarche)	1.0	2.3	6.6	1.9	-1.5	-0.2	1.9	-0.5	-1.9	-2.0	-2.6	-1.0	-1.4	2.0	0.3	-0.1	0.3	-0.2	2.5	1.5
Bilateral oophorectomy (both ovaries removed)	1.7	2.0	8.9	2.1	2.0	1.7	-1.3	1.3	-0.4	-0.0	-0.6	0.2	0.1	1.6	-0.3	3.0	0.7	1.2	1.8	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.6	-0.8	-0.4	-0.5	0.5	-0.0	-0.9	0.0	0.1	-0.7	-1.8	0.1	-1.9	0.1	-0.9	-0.7	0.2	-1.0
Tinnitus: Yes, but not now, but have in the past	3.4	3.6	12.2	2.5	0.8	1.9	0.8	1.8	-2.3	-1.7	-1.3	-1.6	-0.6	2.4	-0.5	1.3	2.8	3.5	1.8	1.8
Qualifications: CSEs or equivalent	0.3	0.5	1.8	-0.3	-0.2	-1.3	-0.3	-1.3	0.1	0.2	-0.0	0.4	-0.4	-0.2	0.2	0.2	-1.1	-1.0	-0.1	-1.1
Serious illness, injury or assault to yourself	2.0	2.5	5.5	-1.8	1.1	-0.8	-1.6	-0.6	2.2	2.2	1.8	1.7	1.5	-1.9	1.2	1.4	-1.2	-1.1	-2.3	-0.9
High blood pressure	1.9	5.4	16.1	-2.6	3.1	0.6	-4.0	1.0	2.8	2.3	3.0	2.0	2.5	-3.1	0.9	2.0	0.1	0.4	-3.2	-0.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.6	-0.0	-0.6	-0.9	-0.3	-0.6	-1.3	-0.1	-0.4	0.5	-0.4	0.8	-1.1	-0.9	0.3	0.0	0.9	0.0
Multivitamins +/- minerals	0.6	0.8	2.7	-0.3	-1.7	-1.6	1.1	-0.7	0.2	-0.5	0.3	-0.1	0.1	-0.7	1.2	-1.1	-1.1	-0.3	-0.6	-1.0
Stomach or abdominal pain in last month	2.5	3.2	12.5	3.5	-1.8	0.6	1.5	-0.0	-1.3	-2.8	-2.6	-0.8	-1.3	1.5	1.0	1.2	1.1	1.0	2.8	1.6
Supplements: Glucosamine	1.7	2.3	9.2	1.5	-1.7	-0.6	3.0	-0.8	-1.9	-1.2	-2.4	-0.3	-1.6	2.5	-0.3	0.7	0.3	-0.6	1.7	-0.1
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	7.3	-0.8	-2.7	-2.3	1.7	-2.2	0.2	0.1	-0.2	0.3	0.1	-0.8	1.3	-1.6	-1.1	-2.1	-0.6	-1.2
Medication: Atenolol	1.4	1.7	5.3	-2.0	-0.7	-1.4	0.1	-1.3	1.6	1.2	1.3	1.4	0.7	-1.6	0.5	0.4	-0.4	-1.2	-2.3	-1.8
Medication: Levothyroxine sodium	0.9	1.5	7.4	0.5	2.0	2.7	-1.6	0.4	0.7	0.8	-0.2	1.0	-0.1	0.9	-0.6	2.5	0.7	0.6	0.6	1.1
Sitting height	0.2	1.5	5.2	-0.9	1.7	0.5	-0.8	-0.4	2.3	1.5	0.4	1.6	1.7	-1.1	1.1	0.8	-1.0	-0.0	-1.6	-0.7
Chronic bronchitis/emphysema (father)	2.0	2.3	6.9	-2.6	1.3	-0.7	-2.1	0.6	1.8	1.6	2.0	0.6	1.8	-1.9	0.0	0.4	-0.7	-0.3	-2.6	-0.7
High blood pressure (mother)	0.7	1.0	2.8	-1.1	-0.6	-1.0	-0.2	-0.9	1.3	0.4	0.3	0.1	-0.8	-1.5	-0.1	-0.7	-1.5	-1.7	-1.2	-1.4
Body mass index (BMI)	0.3	1.2	3.1	-1.3	1.8	0.7	-1.5	-0.5	1.6	1.2	1.1	0.7	0.3	-1.0	0.4	1.4	-0.3	-1.1	-0.9	-0.9
Impedance of leg (left)	0.7	3.4	12.1	-1.9	3.4	1.4	-3.5	2.3	1.1	1.9	2.9	0.2	1.2	-0.6	-1.4	-0.1	-0.9	1.4	-1.8	0.4
Leg predicted mass (left)	0.1	0.5	1.7	0.4	-0.3	0.4	1.2	-1.3	0.6	-0.5	-1.3	-0.1	-0.3	-0.1	0.7	0.9	0.1	-0.9	0.2	-0.5
Trunk fat mass	0.5	2.1	12.2	-1.0	3.5	1.7	-1.8	0.5	2.0	1.4	1.3	0.7	0.1	-0.1	0.1	2.3	-0.6	-0.0	-1.1	-1.1
Waist circumference	0.3	1.1	2.8	-1.4	1.3	-0.1	-0.8	-1.1	1.5	0.8	0.8	0.7	0.0	-1.4	0.8	1.4	-0.7	-1.7	-0.8	-1.2
Number of incorrect matches in round	0.7	1.1	3.8	-0.9	-2.0	-1.7	0.7	-1.3	0.8	0.3	0.7	0.8	0.7	-1.4	0.8	-1.0	-0.1	-1.5	-1.0	-0.1
Past tobacco smoking	0.7	1.3	7.2	1.2	-2.7	-1.4	2.1	-1.2	-0.7	-0.5	-0.3	0.7	-0.4	1.2	0.4	-0.1	1.4	0.3	0.5	-0.9
Alcohol usually taken with meals	1.4	2.3	9.8	-1.1	-0.4	-0.8	-0.4	-0.9	2.1	1.7	1.6	1.6	1.8	-1.1	3.1	-0.3	-1.5	-0.7	-1.9	-1.6
Nervous feelings	0.4	0.8	2.7	1.5	-0.4	0.2	0.4	0.1	-0.3	-1.4	-1.5	-0.8	-0.9	0.2	-0.1	-0.2	0.4	0.2	1.6	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	5.0	1.0	0.4	0.5	-0.4	1.2	-1.3	-1.4	-0.7	-1.7	-1.1	0.2	-2.2	-0.6	-0.5	0.6	0.9	1.1
Hearing difficulty/problems with background noise	0.7	1.2	3.2	1.6	1.0	1.7	-0.3	1.2	-0.9	-0.6	-0.5	-0.3	-1.1	1.8	-1.4	1.1	0.3	0.8	0.9	0.8
Hair/balding pattern: Pattern 2	1.0	1.3	4.1	-0.3	-2.0	-1.3	0.8	-1.8	1.1	0.1	0.0	1.9	-0.4	-0.2	1.9	-0.5	-0.9	-1.3	-0.1	-0.9
Had menopause	0.4	0.5	2.1	0.6	0.5	-0.3	0.3	0.9	-0.9	-0.7	-0.4	-0.3	0.3	0.2	0.2	0.1	1.3	0.7	0.4	1.4
Had other major operations	1.7	2.0	6.8	-1.3	1.9	1.3	-2.6	1.3	1.0	1.4	2.1	1.3	1.6	-1.7	-0.1	1.3	0.3	0.7	-1.4	0.9
Forced vital capacity (FVC)	0.8	2.9	7.4	1.7	-0.3	0.3	1.1	0.4	-2.0	-2.4	-2.7	-2.2	-2.4	1.8	-2.0	-1.7	-0.6	0.8	2.2	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	6.8	-0.9	-0.7	-0.5	1.3	0.3	-1.4	-0.7	-0.1	-1.5	-2.6	0.5	-2.6	-1.3	-0.4	-0.4	0.3	-1.5
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	4.7	0.5	-2.1	-1.6	2.2	-1.3	-0.7	-1.5	-1.7	-0.7	-1.2	-0.6	0.2	-1.6	-0.8	-1.5	1.0	-0.3
Qualifications: None of the above	0.4	0.9	3.3	0.4	1.7	0.2	-1.6	0.3	0.7	0.8	0.8	1.3	1.3	-0.3	1.1	1.8	0.2	0.1	0.2	0.2
Financial difficulties in last 2 years	0.4	0.5	2.5	0.5	1.0	0.7	0.2	0.4	-0.2	0.6	-0.4	-0.5	-0.6	1.1	-1.3	1.6	-0.4	0.4	-0.2	-0.5
Mouth/teeth dental problems	1.2	1.9	7.0	-2.6	-0.8	-0.0	-0.3	-1.3	1.7	1.7	1.6	0.9	0.6	-1.4	0.7	-1.1	-0.6	-0.7	-2.1	-1.9
Heart attack	2.7	3.4	9.1	-1.3	0.9	0.2	-1.8	-0.5	2.6	2.2	1.7	2.7	3.0	-2.0	2.7	1.5	0.1	-0.5	-2.7	0.1
Allergy	0.3	0.6	1.7	-0.7	0.9	1.0	-0.5	0.7	1.3	0.3	0.7	-0.4	0.6	-1.2	1.0	0.7	-0.4	0.1	-1.0	-0.2
Pain all over the body in last month	1.2	1.3	4.6	1.0	0.4	0.1	0.0	1.4	-1.6	-1.4	-0.4	-2.1	-0.7	0.5	-1.8	0.4	1.2	1.1	1.1	1.3
Diabetes (self-reported)	3.5	5.4	14.6	-2.6	1.6	-0.7	-2.2	-0.3	2.3	3.2	3.2	3.1	3.5	-2.4	1.8	2.1	-0.1	-0.4	-3.8	-0.8
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	2.9	-0.1	-0.5	-1.5	-0.6	-1.4	0.6	0.5	0.0	1.7	1.1	-0.1	1.5	-0.3	-0.5	-0.7	0.0	-0.2
Medication: Ramipril	2.2	2.8	9.8	-1.0	0.6	-0.6	-1.4	-1.1	2.0	1.5	1.0	2.4	2.4	-1.6	2.6	3.1	-0.1	-1.2	-1.7	-0.0
Medication: Simvastatin	0.4	0.5	2.0	0.1	-0.1	-0.8	0.5	0.3	-0.3	-0.7	-0.3	0.2	1.1	-0.7	1.1	1.4	1.4	0.2	-0.1	0.9
Fluid intelligence score	0.4	0.9	1.8	0.6	-0.3	1.0	1.3	0.3	-1.2	-1.2	-1.4	-0.8	-1.3	1.1	-1.0	-0.8	0.6	0.2	0.7	0.8
Illnesses of siblings	0.3	0.5	1.6	0.6	-1.0	0.4	0.5	0.2	-0.6	-1.0	-0.6	-1.0	-0.9	0.3	-0.6	-1.3	0.0	0.3	0.9	-0.4
Neuroticism score	0.6	1.3	4.5	2.1	-0.1	1.2	0.4	0.2	-0.3	-1.4	-1.9	-0.8	-1.4	1.4	-1.1	0.3	0.4	0.3	1.6	1.4
Weight	0.2	0.8	3.7	-0.6	1.9	1.2	-0.8	-0.3	1.4	0.6	0.2	0.1	0.3	-0.5	0.4	1.8	-0.1	-0.5	-0.5	-0.4
Impedance of arm (right)	0.6	2.6	9.6	1.9	1.7	0.5	0.2	1.9	-0.8	-0.7	-0.9	-1.0	-3.1	3.0	-2.3	1.1	-0.9	1.8	0.8	-1.2
Arm fat percentage (right)	0.5	2.0	10.4	-0.5	3.2	1.1	-1.8	0.5	1.8	1.4	1.1	0.8	-0.7	0.5	-0.3	2.7	-0.9	-0.1	-0.8	-1.8
Trunk fat-free mass	0.1	0.7	2.0	0.4	-0.7	-0.0	1.1	-1.4	0.5	-0.4	-1.2	0.1	1.1	-0.6	1.4	1.0	0.5	-0.9	0.3	0.7
Hip circumference	0.2	0.7	3.5	-0.5	1.6	0.4	-0.4	-0.6	1.3	0.6	0.2	0.6	-0.0	-0.2	0.5	1.9	-0.3	-0.8	-0.6	-1.0
Time employed in main current job	0.4	0.5	2.0	0.9	0.2	0.8	0.7	0.3	-0.5	-0.2	-0.4	0.2	-0.3	1.4	-0.4	0.4	0.8	1.1	1.0	0.3
Alcohol intake versus 10 years previously	1.1	1.7	7.3	-0.7	-1.9	-1.6	1.2	-1.6	-0.6	-1.0	-0.7	-0.7	-1.2	-1.0	-0.1	-2.7	-1.0	-1.9	0.2	-0.9
Father’s age at death	3.5	4.7	11.0	2.4	-2.6	-0.1	3.2	-0.1	-2.3	-3.3	-3.3	-2.2	-2.2	1.7	-1.3	-2.2	1.1	-0.6	2.9	1.0
Worrier / anxious feelings	0.2	0.4	1.4	0.4	0.5	-0.3	-1.0	-0.4	1.2	0.3	0.1	1.1	0.5	-0.5	0.9	0.8	0.2	-0.6	0.4	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.5	0.8	-0.6	0.0	-0.7	-0.7	-0.2	-0.4	-0.3	-0.2	-1.0	-0.2	-1.2	-0.4	-0.4	-0.4	0.8	0.0
Falls in the last year	1.6	2.2	4.7	1.6	0.6	1.1	0.7	1.1	-2.0	-1.5	-1.6	-1.5	-2.0	1.8	-2.2	0.7	0.7	1.2	2.0	1.1
Hair/balding pattern: Pattern 3	1.3	1.9	8.9	-0.2	-0.6	-0.1	0.7	-0.4	-1.1	-0.7	-1.2	-1.7	-3.0	0.7	-2.8	-1.6	-1.1	-1.2	0.9	-1.7
Number of live births	1.1	1.5	6.9	0.6	2.6	0.7	-2.1	1.9	-0.6	0.3	0.6	-0.9	0.4	0.4	-0.7	1.7	0.2	1.9	0.1	0.9
Forced expiratory volume in 1-second (FEV1)	0.9	3.1	9.0	1.9	-1.1	0.2	1.6	-0.2	-2.0	-2.4	-2.6	-2.0	-3.0	2.0	-2.0	-1.2	-0.7	0.5	2.2	-0.4
Pulse rate	0.2	0.4	1.8	-0.1	0.0	0.3	0.2	0.7	-0.1	0.7	1.2	0.2	0.8	-0.2	0.1	1.0	1.3	0.9	-0.7	0.2
Happiness	0.3	0.4	2.1	0.1	-0.2	-0.5	0.8	-0.2	-0.1	0.3	0.0	0.6	-1.0	0.9	0.0	-0.2	-1.3	0.2	0.2	-1.4
Noisy workplace	0.6	0.8	4.2	0.9	1.2	-0.7	-1.5	0.3	0.4	-0.0	-0.4	0.0	1.5	-1.0	0.1	0.4	0.1	0.0	0.7	2.0
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.7	-1.6	-0.5	-0.4	0.7	0.3	-0.4	0.7	1.1	-0.2	0.2	-1.0	-0.4	-1.7	0.0	0.6	-1.6	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	-1.0	0.6	0.3	-0.9	-0.2	1.4	1.1	1.4	0.9	0.2	-0.3	0.1	0.4	-0.8	-0.2	-1.3	-1.0
Mouth/teeth dental problems: Dentures	0.6	0.9	4.0	1.1	0.6	0.2	0.1	1.3	-0.6	-1.2	-0.7	-0.9	1.0	-0.1	0.4	0.8	1.2	1.2	0.9	2.0
Asthma	0.6	1.3	6.4	1.1	-0.2	0.2	0.3	1.1	-1.6	-1.0	-0.5	-1.0	0.6	0.5	-0.6	-0.2	2.5	1.5	0.6	2.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.0	0.7	-0.7	0.4	1.1	-0.9	0.3	0.2	-1.1	0.1	-1.2	1.4	-0.9	0.8	-0.5	-0.8	0.2	-0.4
Medication: Cholesterol lowering	0.5	0.8	4.3	-0.4	0.1	-0.1	-0.7	-0.4	0.5	1.0	0.8	2.1	1.1	-0.3	1.2	1.7	0.4	-0.4	-0.7	-0.2
Depression (self-reported)	0.2	0.2	1.0	0.5	-0.8	-0.2	0.2	-0.8	0.2	-0.5	-1.0	0.2	0.1	0.1	0.7	0.6	0.0	-0.0	0.1	-0.1
Medication: Lansoprazole	1.5	1.7	3.5	1.3	1.4	0.9	-0.3	1.5	-1.7	-1.3	-1.2	-0.9	-0.5	1.5	-1.3	0.4	1.5	1.9	1.9	1.6
Prospective memory result	0.1	0.2	0.5	0.1	-0.0	0.4	-0.4	-0.2	-0.6	0.3	-0.2	-0.6	0.2	0.4	-0.7	-0.6	-0.2	0.3	0.5	0.4
Lung cancer (father)	1.0	1.1	3.6	1.9	0.8	-0.1	0.2	0.7	-1.1	-0.8	-1.0	-1.1	-0.7	1.1	-1.2	1.1	1.3	1.2	1.2	1.2
Illnesses of mother	0.4	0.5	1.4	1.1	-0.4	-0.6	0.8	-0.1	-0.8	-0.9	-0.8	-0.8	-0.4	1.1	-0.2	-0.3	1.0	0.6	1.2	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	10.8	1.6	-0.7	0.2	1.2	0.1	-1.9	-2.5	-2.5	-2.1	-3.3	1.9	-2.3	-0.9	-1.1	0.4	1.6	-0.6
Pulse wave Arterial Stiffness index	3.6	4.2	10.9	-2.1	2.7	1.1	-3.2	1.4	2.1	2.2	3.1	0.7	3.3	-3.0	0.5	0.6	0.2	0.0	-2.3	1.1
Impedance of arm (left)	0.4	1.9	7.0	1.9	1.8	0.9	0.1	1.7	-0.6	-0.6	-0.8	-0.9	-2.2	2.6	-1.7	1.0	-0.5	1.9	0.9	-0.5
Arm fat mass (right)	0.3	1.3	6.6	-0.5	2.6	1.2	-1.5	-0.0	1.6	1.1	0.7	0.7	-0.3	0.1	-0.1	2.3	-0.5	-0.4	-0.5	-1.2
Trunk predicted mass	0.1	0.7	1.9	0.5	-0.7	0.0	1.1	-1.4	0.5	-0.4	-1.2	0.1	1.1	-0.5	1.4	1.0	0.5	-0.8	0.3	0.8
Standing height	0.1	1.3	3.7	1.8	0.8	1.4	1.3	0.5	-0.4	-1.3	-1.9	-1.2	0.2	1.1	0.0	1.0	0.6	1.3	0.9	1.4
Length of working week for main job	1.4	1.6	4.6	0.6	-1.9	-0.6	2.2	-1.9	-0.2	-0.3	-1.3	0.5	-1.5	1.5	0.6	-0.9	-1.1	-0.7	1.4	-1.6
Exposure to tobacco smoke at home	0.7	0.7	1.9	-0.4	0.3	-0.8	-1.4	-0.9	1.4	0.5	0.2	0.8	0.0	-0.7	1.4	0.2	-1.2	-0.8	-0.7	-1.1
Breastfed as a baby	1.0	1.3	4.2	-0.7	0.3	-0.0	-1.3	0.8	1.6	0.6	1.9	0.1	1.5	-2.1	1.0	-1.5	-0.7	0.0	-1.2	0.1
Tense / ‘highly strung’	1.4	2.3	5.7	2.2	1.3	2.0	-0.5	2.2	-1.2	-1.0	-0.7	-0.9	0.0	1.3	-1.0	1.6	1.1	2.4	1.3	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.4	0.7	0.7	1.8	0.1	0.7	-0.6	-1.2	-1.5	-0.9	-0.8	0.3	-1.2	0.6	0.5	0.3	1.0	2.1
Hair/balding pattern: Pattern 4	0.7	1.7	5.3	-1.0	1.2	0.4	-1.8	0.4	2.0	0.9	1.4	0.9	2.3	-1.7	1.9	0.8	-0.3	-0.1	-1.4	0.3
Birth weight of first child	3.3	6.0	15.6	2.5	-2.5	-0.4	4.0	-0.5	-3.0	-3.1	-3.3	-2.8	-3.3	3.1	-1.9	-1.7	1.0	0.2	3.0	0.1
Peak expiratory flow (PEF)	0.2	0.5	3.1	1.3	0.1	-0.3	0.3	-0.0	-0.5	-0.4	-0.8	0.2	-0.3	1.2	-0.1	1.8	0.3	0.9	0.3	-0.0
Pulse wave reflection index	1.4	1.8	5.7	-1.4	1.3	0.3	-2.3	0.4	1.8	1.0	1.5	0.2	2.1	-2.4	0.8	-0.8	-0.7	-0.2	-1.6	0.5
Ever highly irritable/argumentative for 2 days	1.4	1.7	6.4	0.3	2.1	2.0	-1.9	2.5	-0.4	-0.5	-0.2	-1.4	-0.2	0.3	-1.5	-0.5	0.7	1.9	0.5	1.4
Loud music exposure frequency	0.4	0.4	1.8	-0.6	0.3	-0.3	-0.5	-0.4	0.9	0.8	1.0	0.7	0.8	-0.7	-0.3	0.4	0.3	-0.1	-1.3	-0.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	4.5	-1.7	-0.8	-0.7	0.3	-1.1	1.0	1.5	1.0	1.0	0.1	-0.6	0.4	0.0	-1.6	-1.3	-1.9	-2.1
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	5.3	1.3	0.2	0.1	0.4	-0.1	-1.1	0.2	-0.9	0.7	-1.2	2.3	-0.8	0.8	-0.3	0.1	1.1	-0.4
Blood clot in the leg (DVT)	0.9	1.1	3.3	0.9	-1.2	-0.7	1.8	-1.1	-0.4	-0.6	-1.6	0.0	-1.1	1.8	0.1	-0.4	-1.1	-1.1	1.0	-0.7
Medication: Paracetamol	0.4	0.7	2.3	0.7	-0.7	-0.6	0.8	-1.5	1.0	-0.2	-1.2	0.7	0.4	0.3	1.5	0.5	-0.8	-0.7	0.6	-0.3
Headache pain in last month	1.5	2.6	6.6	1.9	-1.1	0.5	2.3	0.5	-1.6	-2.4	-2.6	-1.7	-1.6	1.3	-1.4	0.1	1.9	1.2	1.7	1.2
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	9.6	1.3	-0.9	0.3	1.4	0.4	-2.0	-1.9	-1.6	-3.1	-2.0	1.4	-2.1	-2.1	0.2	0.4	2.0	1.0
Glaucoma (self-reported)	0.2	0.2	1.9	-0.0	-0.7	-0.3	-0.0	-0.6	-0.2	0.0	0.3	-0.1	-0.2	-0.1	0.1	-0.6	0.3	-1.4	0.8	-0.0
Gout (self-reported)	0.9	1.2	3.0	-1.4	1.5	0.1	-1.7	0.1	0.9	1.3	1.4	1.5	1.3	-1.3	0.6	0.7	-1.2	-0.6	-0.8	0.1
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	3.8	-0.4	1.6	1.2	-1.5	-0.4	1.2	1.7	0.5	1.3	0.9	-0.0	-0.2	1.9	0.0	-0.1	-0.3	0.3
Medication: Amlodipine	0.2	0.2	1.2	-0.2	-0.3	-0.5	0.7	-0.0	-0.9	-0.5	-0.5	0.1	-0.3	0.1	0.3	1.1	0.5	-0.4	-0.1	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.6	2.6	-0.7	0.0	-1.1	-0.3	0.1	-0.1	-0.4	-0.2	-0.5	1.2	-1.3	0.4	-1.6	-0.5	-0.6	-0.2	1.1
Birth weight	4.4	9.6	19.7	3.2	-0.8	1.3	3.0	1.0	-4.3	-4.3	-4.1	-4.2	-4.4	3.3	-3.8	-1.1	1.5	1.8	4.1	0.7
Chronic bronchitis/emphysema (mother)	1.1	1.3	3.8	0.0	2.0	1.5	-1.0	1.9	-0.1	0.9	1.5	0.2	1.3	0.0	-0.9	1.0	0.8	1.5	-0.4	1.2
High blood pressure (siblings)	0.5	0.8	2.5	-1.6	0.5	-1.2	-0.6	-0.0	0.6	1.2	1.0	0.6	0.8	-1.0	0.0	0.6	-1.0	-0.6	-1.3	-0.6
Forced vital capacity (FVC), Best measure	0.8	3.0	7.4	1.2	-0.3	0.1	1.0	0.7	-2.0	-2.6	-2.5	-2.7	-2.7	1.1	-2.6	-1.9	-1.2	0.4	1.4	0.1
Body fat percentage	0.8	3.2	16.8	-1.4	4.1	1.6	-2.6	0.9	2.3	1.9	2.1	0.9	0.3	-0.4	-0.1	2.4	-0.8	0.1	-1.5	-1.3
Leg fat percentage (right)	1.4	5.1	17.4	-3.2	4.2	1.3	-3.6	1.0	2.7	2.7	3.3	0.8	1.4	-2.0	-0.2	1.6	-0.9	-0.2	-2.7	-1.1
Arm fat-free mass (right)	0.2	0.9	4.4	-0.3	0.3	0.9	-0.1	-1.1	1.1	0.5	-0.1	0.6	2.1	-1.1	1.7	0.8	0.6	-0.7	-0.2	1.1
Exposure to tobacco smoke outside home	1.4	1.8	3.7	1.3	1.2	1.8	-0.0	1.4	-1.6	-1.2	-0.5	-1.4	-1.3	1.7	-1.4	0.4	1.1	1.8	1.9	1.4
Comparative body size at age 10	0.2	0.6	3.0	-0.1	0.1	1.5	-0.5	0.9	-0.2	-0.9	-0.1	-1.1	-0.6	-0.3	-0.5	-1.7	0.1	0.4	0.8	0.4
Number of full brothers	2.2	2.8	7.4	2.5	-0.8	0.2	1.5	-0.3	-2.5	-1.8	-2.7	-0.6	-1.9	2.5	-1.2	0.4	0.7	0.5	2.7	0.6
Worry too long after embarrassment	1.9	3.2	8.7	2.9	0.8	2.9	-1.0	1.5	-1.0	-1.8	-1.6	-0.9	-1.2	1.8	-0.8	1.1	1.3	1.3	2.8	2.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	4.2	1.1	0.8	1.5	0.7	1.5	-1.2	-1.4	-1.2	-1.6	-0.9	1.0	-1.0	0.6	1.2	1.3	0.9	2.0
Wheeze or whistling in the chest in last year	1.0	1.9	5.2	0.6	1.1	1.3	0.0	1.9	-1.8	-1.5	-1.0	-2.3	-0.2	0.5	-1.9	0.1	1.0	1.5	1.2	2.2
Number of children fathered	0.9	1.0	4.5	0.2	0.5	-0.2	-0.3	-0.5	1.3	2.1	0.9	1.8	1.5	1.0	1.2	0.9	0.0	0.1	-0.1	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.5	1.1	0.8	0.5	-0.2	1.1	-0.7	0.1	0.2	-0.1	0.3	0.6	-0.8	-0.2	0.7	0.6	0.5	1.2
Age at first live birth	1.9	3.3	14.8	-1.5	-3.0	-0.7	0.9	-2.7	1.2	-0.1	-0.3	0.4	-0.2	-2.1	1.7	-3.9	-1.6	-2.7	-0.9	-1.3
Pulse wave peak to peak time	3.8	4.5	11.2	2.4	-2.5	-1.0	3.3	-1.3	-2.3	-2.4	-3.3	-0.9	-3.3	3.1	-0.6	-0.5	-0.0	0.3	2.5	-0.8
Health satisfaction	0.7	0.9	4.2	-0.3	1.0	0.3	-1.1	-0.5	1.0	1.7	1.0	1.4	0.7	-0.1	0.2	2.0	-0.4	-0.2	0.2	-0.2
Shortness of breath walking on level ground	0.6	0.7	4.5	0.8	0.1	-0.6	0.1	-0.9	-0.1	0.3	-0.7	1.2	0.4	1.1	1.4	2.1	0.4	-0.2	0.8	0.1
Qualifications: College or University degree	0.2	0.5	1.7	0.8	-1.3	0.3	1.1	-0.3	-0.4	-0.5	-0.6	0.2	0.3	0.5	0.7	-0.9	1.1	0.4	0.9	1.0
Eye problems/disorders: None of the above	0.3	0.3	1.0	0.1	0.8	0.5	-0.5	0.7	0.7	0.1	0.6	0.1	0.6	-0.7	0.7	0.1	0.1	1.0	-0.7	0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.7	-0.2	0.4	0.4	-0.2	0.2	0.1	0.7	0.3	-0.1	0.1	0.2	-0.8	0.4	-0.1	-0.2	-0.6	-0.0
Emphysema/chronic bronchitis	0.9	1.0	2.5	-1.3	-0.8	-1.6	0.3	-0.6	-0.1	-0.6	0.4	-0.6	-1.2	-1.4	-0.7	-1.5	-1.5	-0.9	-0.3	-1.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.4	-0.2	0.1	-0.3	-0.5	0.4	-0.2	0.4	0.7	-0.3	0.1	-0.4	-0.2	-0.2	-0.3	-0.1	-0.4	-0.2
Neck or shoulder pain in last month	0.5	0.7	2.8	-0.3	0.9	0.2	-0.4	1.3	0.3	0.1	0.9	-0.4	1.7	-0.8	-0.3	-0.2	0.8	1.1	-0.9	1.1
Medication: Blood pressure	1.4	2.4	6.4	-1.4	1.0	-0.4	-1.2	-0.1	2.1	1.7	1.4	2.5	1.8	-1.6	1.8	2.1	0.1	0.0	-2.5	-0.9
Angina (self-reported)	1.7	2.2	6.9	-0.5	-1.6	-2.1	0.6	-2.6	1.6	0.2	-0.7	2.3	0.2	-0.5	2.3	1.8	-0.9	-1.8	-1.0	-1.2
Migraine (self-reported)	2.1	2.6	8.3	0.9	-0.1	0.8	0.9	1.6	-2.4	-2.0	-1.7	-2.4	-2.3	1.1	-2.9	-0.2	0.8	1.1	1.5	1.3
Medication: Ibuprofen	0.6	0.8	3.2	0.4	-0.8	0.4	0.9	-1.3	0.6	0.5	-0.8	0.7	-1.3	1.8	-0.6	1.0	-0.5	-0.6	-0.1	-0.9
Medication: Allopurinol	0.9	1.1	3.1	-1.1	1.6	0.4	-1.8	0.6	0.9	0.9	1.3	1.2	1.4	-1.0	0.7	1.5	-0.5	0.0	-0.9	0.7
Medication: Omeprazole	0.9	1.1	5.6	-0.8	-0.2	-0.5	-0.2	-0.7	1.0	-0.1	0.5	0.8	2.0	-1.7	2.4	0.1	-0.1	-0.9	-0.7	0.9
Medication: Seretide 50 evohaler	1.0	1.2	4.8	1.1	0.2	0.5	-0.5	0.9	-1.7	-0.9	-0.3	-0.6	0.3	0.8	-0.7	0.6	2.2	1.4	1.4	1.8
Mean time to correctly identify matches	1.5	2.9	9.4	-0.0	-3.1	-2.3	2.8	-2.4	0.3	-0.8	-0.9	-0.2	0.1	-1.3	2.9	-2.0	-0.8	-2.0	0.3	-0.5
Heart disease (mother)	0.3	0.4	1.0	-0.1	-0.6	-0.7	0.0	-0.6	0.9	0.7	-0.0	0.8	0.3	-0.6	0.5	-0.4	-1.0	-0.7	-0.6	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.1	-0.4	1.3	0.4	-1.2	1.3	-0.3	0.3	1.4	0.0	1.0	0.1	0.3	0.5	0.8	1.3	-0.6	0.5
Whole body fat mass	0.6	2.6	12.8	-1.3	3.6	1.7	-2.1	0.4	2.3	1.8	1.6	0.9	0.7	-0.6	0.3	2.4	-0.5	-0.1	-1.4	-1.0
Leg fat mass (right)	1.0	3.7	15.1	-2.4	3.9	1.7	-2.8	0.8	2.4	2.2	2.6	0.6	1.3	-1.6	0.0	1.8	-0.6	-0.1	-2.2	-0.9
Arm predicted mass (right)	0.2	0.8	3.6	-0.3	0.3	0.9	-0.1	-1.0	0.8	0.3	-0.2	0.5	1.9	-1.1	1.6	0.9	0.6	-0.6	-0.2	1.2
Pulse rate, automated reading	0.5	1.5	4.3	-1.0	0.8	-0.3	-1.6	-0.1	1.3	1.6	2.1	1.2	1.5	-1.1	1.6	1.4	-0.6	-0.0	-1.3	-0.7
Alcohol intake frequency.	0.2	0.5	1.6	0.4	-1.1	-0.6	0.6	-0.2	-0.9	-1.2	-0.1	-1.1	-1.2	-0.6	-0.9	-0.7	0.2	0.2	0.4	-0.5
Comparative height size at age 10	0.4	2.1	6.1	1.7	1.4	1.7	0.2	1.6	-1.1	-1.8	-1.3	-2.1	0.2	0.2	-1.3	0.5	1.6	1.5	1.4	2.5
Number of full sisters	0.3	0.4	1.1	-0.5	0.1	-1.1	-0.1	-0.4	0.6	0.4	0.9	0.6	0.5	-0.6	0.5	-0.3	-0.8	-0.9	-0.2	-0.7
Suffer from ‘nerves’	1.0	1.5	3.6	1.5	0.1	1.2	0.5	0.6	-0.8	-1.9	-1.9	-1.4	-1.8	1.6	-0.5	-0.0	0.2	0.8	1.7	1.3
Overall health rating	0.2	0.4	2.0	-0.1	1.1	1.0	-1.2	0.3	0.3	0.2	0.2	-0.1	0.1	-0.5	-0.8	1.4	0.4	0.3	0.1	0.7
Chest pain or discomfort	0.5	0.7	2.7	0.9	-0.4	0.0	-0.5	-0.1	-1.1	-1.6	-1.1	-0.5	-0.0	-0.4	-0.1	-0.2	0.3	-0.1	1.3	1.7
Had major operations	0.8	1.0	2.6	-0.5	1.4	1.6	-1.5	1.0	0.8	0.8	1.4	1.1	0.5	-0.4	0.1	0.3	0.2	1.2	-1.5	0.0
Age at last live birth	2.1	3.1	12.2	-0.3	-3.5	-1.2	2.3	-2.0	-0.7	-1.4	-1.8	-0.9	-1.7	-0.4	0.8	-3.5	-1.6	-1.8	0.4	-1.2
Family relationship satisfaction	1.0	1.3	4.1	0.3	-1.3	-0.4	2.0	0.1	-1.5	-1.4	-1.5	-1.3	-1.6	1.0	-1.4	-1.2	0.5	0.4	0.4	-0.4
Leg pain on walking	1.2	1.5	3.6	1.7	-0.6	-0.2	1.4	0.4	-1.3	-1.9	-1.8	-1.9	-0.2	-0.1	-0.8	0.3	1.5	0.6	1.3	1.8
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	3.3	-0.6	-0.6	0.1	-0.1	0.8	-0.9	-1.1	-0.5	-1.8	-0.4	-0.2	-0.9	-1.0	1.3	1.0	0.1	0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.4	-0.1	-0.6	-1.3	-0.2	-1.1	0.7	-0.5	-0.1	-0.0	-0.2	-0.8	-0.0	-1.6	-0.6	-1.1	-0.0	-0.8
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.9	0.6	-1.2	-0.6	1.2	-0.3	-1.1	-1.4	-1.0	-0.1	-0.9	0.7	0.8	-1.1	0.0	-0.2	1.3	0.2
Medication: Aspirin	0.2	0.3	0.9	-0.5	0.7	-0.4	-0.2	0.2	-0.0	0.3	0.7	0.6	0.5	-0.5	0.6	1.0	0.3	0.7	-0.8	-0.3
Supplements: Vitamin C	0.5	0.5	1.8	-0.6	-1.3	-1.2	0.5	-0.9	0.3	0.4	0.3	0.7	0.8	-0.5	1.3	-0.3	0.3	-0.8	-0.5	-0.1
Knee pain experienced in last month	0.1	0.2	1.0	-0.6	0.0	-0.2	-0.2	-0.7	0.9	-0.0	-0.4	0.5	0.2	-1.0	0.1	-0.0	-0.2	-0.8	0.1	0.3
Hypertension (Self-reported)	1.8	5.0	13.5	-2.6	2.6	0.4	-3.7	0.6	3.0	2.3	2.6	2.5	2.2	-2.8	1.4	2.3	0.0	0.1	-3.2	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.9	0.2	1.1	0.5	-0.5	0.9	-0.4	0.1	0.4	0.3	1.7	-0.3	0.4	1.2	0.5	0.7	0.1	1.3
Illnesses of father: Heart disease	0.4	0.6	1.9	0.5	-0.3	0.5	0.6	0.8	-0.2	-1.4	-1.1	-1.2	-0.4	0.1	0.2	-1.1	0.7	1.0	0.4	1.0
Illnesses of siblings: Diabetes	0.3	0.4	1.2	-0.5	0.1	-0.2	0.3	0.5	-1.1	-0.9	-0.1	-1.0	-1.0	-0.3	-0.8	-0.8	-0.3	0.0	0.2	0.0
Smoking status: Previous	0.7	1.0	4.8	-0.5	2.2	0.8	-1.6	1.2	0.0	-0.2	-0.4	-1.5	-0.1	-0.7	-0.6	-0.1	-1.5	-0.4	0.4	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.9	-0.7	0.9	1.4	-1.2	0.2	0.9	0.5	0.2	0.6	0.5	0.1	-0.4	0.8	0.1	0.3	-0.3	1.0
Whole body fat-free mass	0.1	0.6	2.2	0.4	-0.6	0.2	1.1	-1.5	0.5	-0.5	-1.3	0.1	0.6	-0.5	1.3	0.9	0.3	-0.9	0.3	0.3
Leg fat-free mass (right)	0.1	0.7	2.9	0.8	-0.8	0.5	1.6	-1.4	0.1	-1.0	-1.7	-0.4	-0.6	0.1	0.7	0.5	0.1	-0.9	0.6	-0.4
Arm fat percentage (left)	0.5	2.0	11.2	-0.5	3.3	1.6	-1.9	0.6	1.7	1.3	1.1	0.6	-0.5	0.4	-0.3	2.6	-0.5	0.1	-0.7	-1.3
Average weekly red wine intake	0.4	0.5	2.1	-1.5	-0.5	-0.1	-0.2	-0.7	0.5	0.6	0.5	0.7	0.7	-0.9	1.3	-0.5	-0.4	-0.9	-0.7	-0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.6	0.6	0.3	-0.2	0.2	-0.1	-0.5	-0.4	-0.5	-0.8	-0.2	0.3	-0.1	0.4	0.0	0.4	-0.0	0.1
Mood swings	0.7	1.2	4.5	1.2	-0.6	0.2	0.8	-0.5	-0.8	-1.3	-2.1	-0.8	-1.9	1.4	-1.3	-0.5	0.1	-0.5	1.6	0.1
Loneliness, isolation	0.2	0.3	1.4	0.0	0.5	0.0	-0.9	0.4	0.4	0.3	0.6	-0.1	-0.1	-0.7	-1.2	-0.1	-0.7	-0.2	-0.1	0.5
Long-standing illness, disability or infirmity	1.9	2.9	9.1	0.5	2.2	2.3	-1.4	2.0	0.1	0.7	1.1	0.6	1.6	0.6	-0.2	2.9	3.0	2.5	-0.8	1.7
Ever had bowel cancer screening	1.2	1.4	4.3	1.7	-1.1	-0.6	1.9	-0.8	-0.6	-1.3	-2.1	0.3	-0.8	1.3	0.3	1.7	0.6	-0.8	1.2	0.8
Diabetes diagnosed by doctor	3.6	5.9	17.3	-3.1	1.2	-1.4	-1.8	-0.7	2.6	3.1	3.2	3.0	3.6	-3.0	2.3	1.1	-0.5	-0.7	-4.2	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	3.6	-0.9	-1.2	-1.9	0.7	-1.2	0.4	0.5	0.5	1.2	0.5	-1.2	1.3	0.0	-0.7	-1.5	-0.9	-0.9
Friendships satisfaction	1.4	1.7	4.0	1.1	-1.2	-0.0	1.5	-0.1	-1.1	-1.6	-2.0	-1.2	-1.9	1.4	-0.9	-2.0	-0.7	0.1	1.8	-0.1
Qualifications: nursing, teaching	0.2	0.3	1.4	-0.0	-0.7	-0.1	1.1	-0.4	0.4	0.4	0.0	0.2	0.4	0.1	0.0	0.6	0.6	0.4	-1.2	-0.1
Commuting to job workplace: Walk	0.5	0.5	1.3	0.2	0.0	1.0	0.6	0.7	-0.7	-0.6	-1.0	-0.5	-0.9	1.1	-0.4	0.6	1.1	1.0	0.1	0.7
Eye problems/disorders: Cataract	0.9	1.0	4.6	1.2	-0.6	-0.5	1.5	-0.4	-1.2	0.1	-1.1	0.2	-0.1	2.1	-0.4	1.8	1.0	-0.1	1.1	0.2
Mouth/teeth dental problems: Mouth ulcers	1.4	2.3	6.4	2.5	0.8	0.4	0.3	1.8	-2.2	-1.9	-1.4	-1.3	-1.5	1.7	-1.3	0.5	0.8	1.2	2.1	1.5
Medication for cholesterol	0.8	1.2	4.2	0.6	-1.9	-0.3	2.1	-0.4	-1.2	-0.5	-0.7	-0.0	-1.5	1.6	-0.8	-1.7	-0.6	-0.1	0.6	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.1	0.2	-0.4	0.2	-0.1	-0.4	0.3	0.3	0.1	1.1	0.6	-0.4	0.6	0.7	0.4	-0.5	0.5	0.8
Back pain experienced in last month	0.2	0.4	1.0	0.3	-0.4	0.3	0.8	-0.7	-0.1	-0.5	-0.9	-0.3	-0.9	0.7	-1.0	0.7	0.5	-0.6	0.5	0.3
Mineral and other dietary supplements	0.3	0.4	1.6	-0.8	0.2	0.2	-0.7	-0.3	0.6	-0.1	-0.3	-0.2	-0.8	-0.2	-1.2	-0.9	-0.1	-0.3	-0.5	-1.0
Breast cancer (self-reported)	0.6	0.8	2.5	0.4	-0.7	-0.2	1.0	0.2	-1.6	-0.8	-0.7	-0.4	-1.0	0.8	-1.2	-1.4	-0.9	-0.2	1.2	-0.2
Asthma (self-reported)	0.7	1.3	6.2	1.0	-0.2	0.3	0.2	1.2	-1.5	-1.3	-0.7	-1.1	0.7	0.2	-0.5	-0.2	2.5	1.4	0.5	2.3
Osteoporosis (self-reported)	0.7	0.9	3.9	1.2	0.6	0.8	-0.6	0.9	0.2	0.0	-0.1	-0.1	1.5	-0.3	1.3	1.3	1.0	0.9	0.1	2.0
Osteoarthritis (self-reported)	0.8	1.1	4.0	1.5	0.5	1.5	0.9	0.2	-0.2	-0.4	-1.3	-0.1	0.2	1.5	-0.3	2.0	1.4	0.5	1.1	1.0
Medication: Aspirin	0.5	0.7	1.8	-1.0	0.8	-0.4	-0.6	0.1	0.4	0.8	1.3	1.1	0.9	-1.0	0.6	1.2	0.3	0.5	-1.3	-0.5
Medication: Gliclazide	1.7	2.0	4.3	-0.8	2.1	1.3	-1.7	2.0	0.5	1.3	1.4	0.8	1.9	-0.8	0.1	1.5	1.2	1.4	-1.7	1.4
Illnesses of father: None of the above (group 1)	0.6	0.7	1.4	0.4	-1.0	-0.8	1.0	-1.1	-1.0	-0.2	-0.4	-0.3	-1.2	0.5	-1.0	-0.8	-0.9	-1.1	1.1	-0.6
Smoking status: Current	0.3	0.4	1.4	0.3	0.4	1.2	0.5	0.4	-0.0	-0.1	-0.4	0.6	-0.5	1.1	-0.7	0.5	1.0	1.1	0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.2	5.5	1.6	-1.5	-1.6	2.0	-1.1	-1.6	-1.7	-2.1	-0.7	-2.3	1.5	-1.1	-0.3	-1.1	-1.1	1.8	-0.4
Whole body water mass	0.1	0.7	2.3	0.5	-0.7	0.2	1.3	-1.5	0.5	-0.5	-1.3	0.1	0.6	-0.3	1.4	0.8	0.3	-0.9	0.4	0.3
Leg predicted mass (right)	0.2	0.8	3.2	0.8	-0.9	0.4	1.8	-1.5	0.1	-1.0	-1.8	-0.4	-0.7	0.2	0.6	0.6	0.1	-1.0	0.7	-0.4
Arm fat mass (left)	0.3	1.4	7.8	-0.5	2.8	1.5	-1.5	0.2	1.6	1.1	0.9	0.5	0.0	-0.0	-0.0	2.2	-0.2	-0.1	-0.6	-0.8
Number of self-reported non-cancer illnesses	1.7	2.9	8.3	-0.9	2.1	0.1	-2.2	0.2	1.7	2.5	1.5	2.5	2.6	-1.2	1.2	2.9	-0.3	-0.1	-1.9	0.1
Average weekly champagne plus white wine intake	0.3	0.4	2.2	-0.3	0.7	1.5	-0.5	0.8	0.1	-0.2	0.4	-0.4	-0.8	-0.0	-0.1	-1.3	-0.5	0.3	0.0	-0.0
Miserableness	0.8	1.5	5.6	0.9	-1.4	-0.5	2.1	-1.1	-1.1	-1.3	-2.4	-1.1	-1.4	0.8	-1.5	-0.1	0.5	-0.7	0.8	0.2
Guilty feelings	0.6	0.9	3.1	1.8	1.1	1.2	-1.2	0.7	0.1	-0.3	-0.6	-0.1	-0.3	1.1	-0.9	1.6	0.4	0.5	0.9	1.3
Wears glasses or contact lenses	0.3	0.4	1.3	0.4	0.5	0.6	0.3	0.5	-0.3	-0.6	-0.6	-0.7	0.5	0.1	0.7	-0.9	0.9	0.5	0.5	1.1
Ever taken oral contraceptive pill	1.0	1.1	6.3	0.4	0.4	0.5	-0.6	-0.6	0.8	1.4	0.6	1.6	0.4	1.1	0.5	2.5	1.3	0.8	-0.8	-1.0
Hearing aid user	1.2	1.3	3.9	-0.9	1.2	-0.2	-1.7	0.0	1.4	1.2	2.0	1.8	0.7	-1.1	0.6	-1.1	-1.7	-0.7	-0.6	-0.6
Mother’s age at death	0.3	0.3	0.9	0.8	-0.5	0.6	0.7	-0.0	0.4	-0.2	-0.6	0.5	0.6	0.8	1.0	-0.3	0.7	0.3	0.5	0.7
Financial situation satisfaction	1.1	1.4	6.0	-1.6	-0.4	-0.7	0.0	-0.5	0.6	0.7	1.1	-0.0	-1.4	-0.8	-0.7	-1.3	-2.4	-1.0	-0.9	-2.3
Tinnitus: Yes, now most or all of the time	1.6	1.8	6.4	-0.8	-1.9	-2.0	0.2	-1.8	1.2	-0.2	-0.1	0.6	-0.0	-1.6	0.9	-1.6	-1.8	-2.5	-0.6	-1.4
Commuting to job workplace: Public transport	0.3	0.3	2.1	0.2	-0.7	-0.3	1.5	-0.3	-0.7	0.6	-0.1	0.3	-0.3	0.8	0.0	1.0	0.6	0.2	0.2	-0.3
Eye problems/disorders: Glaucoma	1.1	1.3	4.8	-1.6	-0.6	-0.9	-0.7	-1.2	1.3	0.8	1.2	0.6	0.3	-1.5	0.6	-1.4	-1.0	-2.2	-0.8	-0.9
Medication: Blood pressure	1.8	3.4	11.0	-2.4	2.0	-0.3	-2.6	0.1	2.0	1.9	2.4	1.3	2.2	-3.3	0.5	1.4	-0.4	-0.8	-2.6	-0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.7	0.4	0.1	0.3	0.6	0.5	-0.4	-1.0	-1.1	-0.9	0.1	0.1	-0.2	0.4	1.3	0.5	0.2	0.7
Supplements: Fish oil (including cod liver oil)	0.8	1.0	5.7	-0.2	-0.8	-1.7	0.4	-0.8	0.5	0.5	1.1	1.3	1.2	-0.8	2.4	0.7	-0.4	-0.5	-0.7	-0.2
High cholesterol (Self-reported)	0.3	0.5	1.6	-0.4	0.8	-0.0	-0.5	0.8	-0.2	-1.0	-0.2	-0.6	0.8	-1.0	0.6	-0.0	0.7	0.7	-0.1	1.3
Medication: Bendroflumethiazide	1.5	2.3	8.1	-2.2	2.0	0.8	-2.8	1.6	1.1	1.2	2.3	0.9	0.9	-2.2	-0.5	0.2	-0.8	-0.1	-1.5	-0.6
Medication: Paracetamol	0.5	0.8	3.2	0.7	-1.1	-0.8	1.1	-1.8	0.8	-0.0	-1.4	0.9	0.2	0.7	1.3	0.7	-0.7	-0.8	0.6	-0.6
Medication: Lisinopril	1.1	1.4	4.9	-0.8	2.2	1.1	-0.6	1.8	0.4	1.0	1.0	0.5	0.7	-0.4	-0.4	2.1	0.7	1.6	-1.6	0.1
Medication: Atorvastatin	2.1	2.6	8.8	-0.8	1.9	-0.2	-2.1	-0.2	1.6	2.1	1.6	2.6	1.6	0.1	2.0	3.0	-0.6	0.4	-1.4	-0.9
Illnesses of father: High blood pressure	0.9	1.1	4.9	-0.2	1.3	2.0	-2.2	1.5	0.8	-0.1	0.8	-0.6	0.4	-0.9	-0.7	0.3	0.2	1.3	-0.8	0.5
Alcohol drinker status: Never	1.0	1.2	4.8	0.7	-1.9	-1.5	1.1	-2.2	-0.3	-0.4	-0.8	1.1	-0.7	0.8	0.2	0.0	-0.5	-1.7	0.9	-0.7
Ever smoked	0.9	1.6	7.6	-0.6	2.8	2.1	-2.4	1.8	0.5	0.6	0.6	-0.4	0.8	-0.9	-0.6	0.5	-0.3	0.8	-0.3	1.2
Basal metabolic rate	0.1	0.5	2.0	0.1	-0.1	0.3	0.8	-1.4	0.8	-0.2	-1.0	0.1	0.5	-0.5	1.1	1.0	0.0	-1.1	0.1	-0.0
Leg fat percentage (left)	1.3	4.9	15.4	-3.1	3.9	1.5	-3.5	0.8	2.7	2.6	3.2	0.9	1.1	-2.0	-0.2	1.5	-1.1	-0.5	-2.6	-1.2
Arm fat-free mass (left)	0.1	0.4	1.1	-0.0	-0.2	0.4	0.6	-1.0	0.4	-0.2	-0.8	-0.1	1.0	-0.6	0.9	0.8	0.5	-0.8	0.2	0.6
Number of operations (self-reported)	2.0	3.0	9.8	0.3	3.1	2.0	-2.3	2.5	-0.0	0.6	1.3	0.6	1.5	0.2	-0.7	2.3	1.7	2.4	-0.8	2.1
Average weekly beer plus cider intake	0.4	0.6	3.2	0.2	0.9	0.3	-1.4	0.8	-0.6	0.3	0.3	-0.0	-0.8	0.8	-1.8	0.4	-0.0	0.3	0.9	0.5
Irritability	0.4	0.7	2.2	0.6	1.4	1.3	-1.2	1.0	0.4	0.9	0.6	0.5	0.1	0.7	-1.5	1.2	-0.3	-0.0	0.1	0.1
Risk taking	0.8	1.1	4.1	1.1	0.1	0.7	0.0	0.5	-1.3	-1.3	-1.4	-1.1	-1.1	0.7	-1.5	-0.4	0.3	0.0	2.0	1.6
Ever had prostate specific antigen (PSA) test	0.7	0.8	4.1	-0.5	-1.6	-1.1	2.0	-1.1	0.1	0.2	-0.6	-0.4	0.9	0.2	0.8	-1.0	0.8	-0.7	-0.6	-0.3
Fractured/broken bones in last 5 years	0.5	0.7	2.4	0.9	0.5	1.5	-0.0	1.0	0.1	-0.7	0.1	-0.6	0.9	-0.7	0.8	-0.8	0.5	0.9	0.4	1.6
Age started oral contraceptive pill	1.3	1.7	6.4	0.8	-0.8	0.7	0.9	1.1	-1.6	-1.6	-0.3	-2.1	-0.3	0.1	-1.1	-0.9	2.5	1.3	0.4	2.0
Diastolic blood pressure, automated reading	4.1	12.7	31.6	-2.3	4.7	1.4	-5.5	0.8	5.1	4.4	4.0	3.6	5.6	-3.2	3.7	3.4	-1.3	-0.2	-3.7	0.6
Ever depressed for a whole week	0.6	0.7	2.1	0.7	-1.1	0.2	1.1	-0.3	-0.2	-1.4	-1.2	-0.6	-1.2	-0.1	-0.4	-1.4	-0.2	-0.4	1.0	0.4
Unable to work because of sickness or disability	1.6	2.1	5.5	0.9	1.0	1.4	-0.2	2.3	-1.4	-1.8	-0.6	-2.2	-0.3	0.6	-1.5	-0.9	1.9	2.3	0.8	1.8
Commuting to job workplace: Cycle	1.3	1.6	6.6	-0.7	-0.1	0.4	-0.0	-1.2	1.1	2.1	0.9	2.6	1.2	0.5	1.3	1.8	-1.0	-0.9	-1.3	-1.3
Myopia	0.2	0.3	0.7	0.3	-0.4	0.7	0.8	-0.2	-0.6	-0.7	-0.2	-0.2	-0.4	0.3	0.6	-0.6	0.4	-0.2	0.8	0.5
Vascular/heart problems diagnosed by doctor	1.7	4.7	11.4	2.4	-2.2	0.4	3.2	-0.3	-2.9	-2.2	-2.6	-2.4	-2.5	3.1	-1.5	-2.1	-0.2	0.0	3.4	0.5
Cholesterol lowering medication	0.4	0.6	2.0	0.1	1.0	-0.6	-0.6	0.8	-0.5	-1.2	-0.5	-1.0	0.4	-0.6	0.4	0.8	0.7	0.8	0.5	1.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	3.0	-0.5	0.2	0.4	-0.2	0.4	0.0	-0.8	0.2	-0.3	1.1	-1.0	1.3	-0.4	0.4	-0.0	0.2	1.7
Pain experienced in last month	0.1	0.2	0.9	-0.0	0.1	0.2	-0.6	-0.1	-0.5	0.8	0.6	0.9	-0.1	0.6	0.3	-0.3	-0.4	0.2	0.2	-0.6
Supplements: Calcium	0.9	1.0	3.8	0.8	1.3	1.3	-1.3	1.8	-0.5	-0.5	-0.0	-1.1	0.3	-0.4	-0.5	-0.4	-0.1	1.0	0.8	2.0
Basal cell carcinoma (self-reported)	2.6	3.1	7.1	1.1	-0.7	0.2	1.2	1.3	-2.5	-2.6	-1.1	-2.7	-2.3	1.1	-2.1	-2.7	1.9	1.8	1.3	0.8
Heart attack/myocardial infarction (self-reported)	3.1	4.0	11.7	-1.5	0.6	-0.1	-1.6	-0.8	2.8	2.4	1.8	2.9	3.4	-2.1	3.3	1.5	0.2	-0.5	-3.0	-0.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.6	1.0	-1.3	-0.9	1.9	-1.4	-0.4	-0.5	-1.7	0.0	-1.1	1.8	0.2	-0.3	-1.2	-1.3	1.1	-0.8
Heart disease (siblings)	1.2	1.5	6.1	0.5	0.7	0.6	-0.9	-0.5	1.5	0.4	0.0	1.6	1.9	-0.3	2.5	1.9	0.9	0.3	-0.7	1.7
Alcohol drinker status: Previous	0.6	0.7	2.5	0.0	1.2	1.1	-0.8	1.6	-0.2	-0.4	0.4	-1.3	-0.3	-0.1	-0.7	1.0	0.5	1.6	-0.2	0.5
Pack years of smoking	0.9	1.3	5.8	-1.6	0.3	-0.8	-0.5	-0.6	1.4	0.2	0.6	0.8	1.4	-2.4	1.5	-1.2	-1.3	-1.4	-0.6	0.1
Impedance of whole body	0.3	1.7	7.8	0.0	2.8	1.2	-1.7	2.3	0.3	0.7	1.2	-0.4	-0.6	1.0	-1.8	0.5	-0.8	1.9	-0.6	-0.2
Leg fat mass (left)	0.9	3.4	13.0	-2.4	3.6	1.7	-2.6	0.6	2.4	2.2	2.4	0.8	1.2	-1.6	0.2	1.7	-0.6	-0.3	-2.1	-1.0
Arm predicted mass (left)	0.1	0.5	1.8	-0.2	-0.2	0.3	0.4	-1.3	0.8	0.1	-0.5	0.3	1.2	-0.9	1.2	0.7	0.1	-1.1	-0.1	0.4