TWAS hub - CHCHD5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2060	0.0440	5.0e-11	0.170	0.130	0.166	0.169	0.169	3.9e-20	1.6e-15	9.4e-20	4.3e-20	4.1e-20
2	GTEx	Artery Aorta	0.1370	0.0590	5.5e-03	0.154	NA	0.105	NA	0.144	7.3e-09	NA	2.2e-06	NA	2.5e-08
3	GTEx	Artery Coronary	0.1310	0.0600	7.0e-03	0.031	NA	0.000	NA	0.001	3.1e-02	NA	3.1e-01	NA	2.8e-01
4	GTEx	Artery Tibial	0.1234	0.0419	6.4e-05	0.083	NA	0.048	NA	0.054	4.9e-07	NA	1.2e-04	NA	4.4e-05
5	GTEx	Brain Cerebellum	0.3020	0.0920	2.2e-05	0.048	NA	0.131	NA	0.126	1.5e-02	NA	1.1e-04	NA	1.5e-04
6	GTEx	Breast Mammary Tissue	0.1230	0.0530	7.8e-03	0.150	NA	0.077	NA	0.134	4.1e-08	NA	8.6e-05	NA	2.2e-07
7	GTEx	Breast Mammary Tissue (Male)	0.0624	0.0764	2.5e-01	0.002	NA	-0.012	NA	-0.011	2.9e-01	NA	8.3e-01	NA	6.9e-01
8	GTEx	Esophagus Mucosa	0.3190	0.0630	1.5e-08	0.162	NA	0.183	NA	0.191	5.4e-11	NA	2.7e-12	NA	7.3e-13
9	GTEx	Lung	0.0971	0.0478	7.6e-03	0.016	NA	0.001	NA	0.007	2.1e-02	NA	2.7e-01	NA	9.0e-02
10	GTEx	Nerve Tibial	0.1964	0.0594	9.1e-05	0.134	NA	0.124	NA	0.126	9.7e-10	NA	4.3e-09	NA	3.3e-09
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1880	0.0710	1.9e-03	0.111	NA	0.074	NA	0.092	1.2e-06	NA	6.8e-05	NA	9.3e-06
12	GTEx	Skin Sun Exposed Lower leg	0.1240	0.0440	2.8e-04	0.089	NA	0.061	NA	0.068	8.6e-08	NA	8.0e-06	NA	2.5e-06
13	GTEx	Testis	0.3230	0.0920	1.3e-03	0.141	NA	0.177	NA	0.188	8.2e-07	NA	2.7e-08	NA	9.4e-09
14	GTEx	Thyroid	0.1300	0.0400	4.2e-05	0.113	NA	0.088	NA	0.094	5.5e-09	NA	2.9e-07	NA	1.1e-07
15	YFS	Blood	0.0429	0.0123	2.2e-16	0.048	0.063	0.068	0.064	0.068	2.3e-15	8.0e-20	2.7e-21	3.4e-20	3.1e-21
16	TCGA	Cervical Squamous Cell Carcinoma	0.1260	0.0600	2.4e-03	-0.004	0.052	0.052	NA	0.024	6.3e-01	1.5e-03	1.4e-03	NA	2.3e-02
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.0407	0.0218	3.1e-03	0.007	0.020	0.025	NA	0.019	5.0e-02	2.4e-03	7.1e-04	NA	2.7e-03
18	TCGA	Brain Lower Grade Glioma	0.0931	0.0373	1.7e-08	0.029	0.082	0.068	NA	0.062	2.8e-04	1.4e-09	3.1e-08	NA	1.5e-07
19	TCGA	Thyroid Carcinoma	0.1290	0.0550	1.1e-06	0.021	0.068	0.044	NA	0.043	3.3e-03	3.5e-07	3.7e-05	NA	4.4e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Smoking status: Previous	7.6	11.4	15.2	-3.7	-3.9	-0.4	-3.6	-3.7	-3.8	-3.8	-3.3	-3.4	-3.6	-3.4	-3.9	-2.9	-3.5	3.7	-2.2	-3.6	-3.4	-2.4
Past tobacco smoking	6.4	11.8	17.2	3.8	3.9	0.4	3.7	4.2	3.8	3.9	3.1	3.4	3.7	3.5	3.9	2.9	3.4	-3.7	2.6	3.5	3.5	2.5
Age started oral contraceptive pill	6.0	7.6	16.7	2.6	2.5	0.4	2.7	3.3	2.5	2.4	2.3	2.3	2.6	2.2	2.6	3.0	2.1	-1.9	3.8	3.3	4.1	3.4
Smoking Status	5.7	13.6	20.3	-4.0	-4.3	0.3	-3.8	-4.5	-4.1	-4.3	-3.0	-3.2	-3.8	-3.9	-4.2	-3.9	-3.9	3.9	-2.5	-3.9	-3.4	-2.9
Seen doctor (GP) for nerves, anxiety, tension or depression	5.1	7.9	13.9	-3.0	-2.7	1.4	-3.0	-3.3	-2.9	-2.8	-2.7	-3.0	-3.1	-2.4	-2.8	-3.7	-2.3	1.3	-2.6	-3.1	-3.4	-2.6
Pack years adult smoking proportion	4.8	7.3	14.6	-3.1	-2.9	-0.8	-3.2	-2.1	-3.0	-2.9	-2.8	-3.3	-3.1	-3.8	-3.0	-3.0	-2.7	2.6	-1.4	-2.1	-2.1	-1.5
Ever smoked	4.5	7.9	15.5	-2.9	-3.0	-0.2	-2.8	-3.9	-2.9	-2.9	-2.2	-2.3	-2.9	-2.7	-3.0	-2.4	-2.6	2.8	-2.5	-3.5	-3.4	-2.6
Pack years of smoking	4.1	6.0	12.6	-2.8	-2.7	-0.5	-2.9	-1.9	-2.8	-2.7	-2.4	-2.9	-2.8	-3.5	-2.7	-2.6	-2.5	2.6	-1.1	-1.9	-1.7	-1.2
Mouth/teeth dental problems: Loose teeth	3.9	4.7	9.1	-2.1	-2.0	0.3	-2.2	-1.4	-2.1	-1.9	-1.8	-1.8	-2.2	-2.1	-2.1	-3.0	-1.7	0.5	-2.9	-3.0	-3.0	-2.6
Number of children fathered	3.8	4.3	5.9	-2.2	-2.2	-2.1	-2.3	-1.6	-2.2	-2.2	-2.4	-2.1	-2.2	-1.9	-2.2	-2.3	-2.3	2.4	-0.8	-1.8	-1.6	-1.7
Primary Biliary Cirrhosis	3.6	5.1	8.5	-2.6	-2.4	-0.2	-2.7	-1.6	-2.5	-2.4	-2.7	-2.4	-2.7	-2.0	-2.5	-2.5	-2.4	2.9	-1.9	-1.7	-1.6	-1.7
Hair/balding pattern: Pattern 2	3.4	4.3	6.7	-2.3	-2.4	-1.2	-2.3	-0.6	-2.4	-2.5	-2.1	-1.8	-2.2	-2.5	-2.4	-2.0	-2.6	2.4	-1.8	-1.8	-1.1	-1.9
Shortness of breath walking on level ground	3.4	4.1	7.6	-2.0	-2.0	-0.4	-2.0	-1.4	-2.0	-1.9	-2.1	-1.7	-1.9	-2.5	-2.1	-2.2	-2.0	0.8	-2.7	-1.9	-2.5	-2.8
Ever highly irritable/argumentative for 2 days	3.1	3.7	13.5	-2.0	-1.9	1.3	-2.0	-3.7	-2.0	-2.0	-1.3	-1.9	-2.1	-2.0	-1.9	-1.6	-1.4	1.6	-1.8	-1.3	-2.3	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.3	7.7	1.8	1.9	-0.6	1.7	1.2	1.9	1.7	1.7	1.3	1.7	1.5	1.9	2.1	1.8	-0.6	2.3	2.0	2.8	2.6
Hair/balding pattern: Pattern 3	2.9	4.4	7.6	2.4	2.3	1.8	2.5	0.2	2.3	2.4	2.5	2.8	2.5	2.6	2.4	2.1	2.5	-1.4	1.7	0.8	1.1	1.5
Blood clot in the leg (DVT)	2.7	3.5	11.0	-1.8	-2.1	0.3	-1.6	0.1	-2.0	-1.9	-1.3	-1.3	-1.5	-2.2	-2.0	-3.2	-2.2	-0.1	-3.3	-0.8	-1.5	-2.5
Age at last live birth	2.7	3.9	11.7	1.6	1.8	0.1	1.4	3.4	1.7	1.8	1.6	1.1	1.4	1.1	1.8	1.9	1.3	-0.9	3.0	2.5	3.3	2.3
Diabetes (mother)	2.6	3.3	7.5	2.0	2.1	-0.6	2.0	1.0	2.1	2.1	1.8	1.5	1.9	2.0	2.2	1.7	2.0	-1.4	2.7	1.0	1.6	1.7
Qualifications: A levels/AS levels or equivalent	2.5	5.5	8.8	2.5	2.4	0.2	2.5	1.3	2.4	2.3	2.3	2.0	2.5	2.8	2.4	2.5	2.4	-1.9	2.9	2.3	2.5	3.0
Leg pain on walking	2.5	3.2	5.7	2.0	2.2	1.9	2.0	0.3	2.2	2.3	2.3	1.7	2.0	2.0	2.1	0.8	2.4	-1.8	1.1	0.4	0.7	1.1
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.2	8.1	-2.5	-2.5	-0.7	-2.5	-2.3	-2.5	-2.5	-2.9	-2.4	-2.5	-2.7	-2.5	-1.9	-2.1	1.8	-1.8	-1.9	-2.8	-1.6
Medication: Bendroflumethiazide	2.5	3.8	10.9	-2.1	-2.1	-0.3	-2.0	-2.1	-2.1	-2.2	-1.9	-1.7	-2.1	-2.3	-2.1	-1.7	-2.1	3.3	-0.8	-1.8	-1.4	-1.3
Medication: Lisinopril	2.5	3.2	7.9	-1.4	-1.2	1.2	-1.4	-2.5	-1.3	-1.1	-1.5	-0.8	-1.5	-1.6	-1.2	-2.0	-1.0	1.4	-2.6	-2.7	-2.8	-2.5
Major Depression (MDD)	2.4	2.9	5.1	-1.8	-1.7	-0.2	-1.7	-1.1	-1.7	-1.3	-2.0	-1.6	-1.8	-1.4	-1.4	-2.3	-1.6	1.0	-2.0	-2.0	-2.0	-2.3
Irritable Bowel Disease (IBD)	2.3	5.5	9.1	-2.8	-2.6	-1.5	-2.9	-0.5	-2.7	-2.4	-2.7	-3.0	-2.8	-2.3	-2.6	-2.6	-2.7	2.5	-2.1	-0.7	-0.9	-1.7
Ulcerative Colitis (UC)	2.3	4.3	7.1	-2.6	-2.3	-0.6	-2.7	0.2	-2.4	-2.0	-2.6	-2.5	-2.6	-1.7	-2.4	-2.5	-2.3	1.3	-2.0	-0.7	-1.4	-1.7
Blood White Count	2.3	17.2	76.6	-4.1	-3.9	-8.8	-4.7	-0.3	-4.0	-3.7	-5.5	-5.7	-4.2	-4.7	-4.0	-3.4	-3.6	1.7	-2.9	-1.3	-2.7	-2.0
Maternal smoking around birth	2.3	3.4	5.9	-2.0	-1.9	-1.3	-2.1	-2.1	-1.9	-1.9	-2.1	-2.1	-2.0	-2.0	-2.0	-1.7	-1.8	2.4	-1.5	-0.9	-1.1	-0.7
Had major operations	2.3	2.7	8.8	-1.5	-1.5	0.1	-1.5	-3.0	-1.5	-1.4	-0.9	-1.1	-1.5	-1.0	-1.4	-1.7	-1.2	1.5	-1.8	-2.2	-2.5	-1.9
Average weekly beer plus cider intake	2.3	3.4	10.4	-1.7	-1.8	-0.1	-1.7	-2.3	-1.8	-1.7	-1.6	-1.1	-1.7	-1.2	-1.8	-2.0	-1.4	1.3	-1.7	-3.2	-2.5	-2.3
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	8.9	-1.7	-2.0	0.1	-1.5	0.2	-1.9	-1.7	-1.3	-1.3	-1.5	-2.1	-1.9	-2.9	-2.0	-0.2	-3.0	-0.6	-1.4	-2.2
Eye problems/disorders: None of the above	2.2	2.6	4.9	1.8	1.7	0.3	1.9	1.5	1.8	1.6	1.7	1.3	1.9	1.4	1.7	1.3	1.4	-2.2	0.9	2.2	1.7	1.1
Alcohol drinker status: Never	2.2	2.6	3.6	1.8	1.8	-0.0	1.8	1.6	1.9	1.9	1.8	1.7	1.9	1.9	1.9	1.3	1.7	-0.9	1.7	0.9	1.7	1.5
Mean Putamen Volume	2.1	2.5	4.5	1.8	2.0	1.4	1.8	0.5	2.0	2.0	1.5	1.6	1.7	1.6	2.0	1.4	2.1	-1.0	1.4	0.2	1.0	1.1
Blood Red Count	2.1	20.6	30.9	-5.0	-4.7	-4.9	-5.3	-3.0	-4.8	-4.5	-4.8	-5.6	-5.1	-4.8	-4.8	-4.1	-4.9	4.0	-3.8	-2.6	-4.0	-4.4
Ever taken oral contraceptive pill	2.1	2.3	4.5	1.7	1.7	0.2	1.6	0.6	1.7	1.7	1.4	1.6	1.6	1.8	1.7	1.7	2.1	-2.0	0.4	1.1	0.5	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.5	9.5	-1.8	-1.8	1.4	-1.7	-3.1	-1.8	-1.8	-1.3	-1.4	-1.8	-1.6	-1.8	-0.4	-1.3	0.9	-1.4	-0.3	-1.9	-0.2
Breast Cancer	1.9	4.5	8.5	2.1	2.4	1.0	2.0	1.3	2.4	2.6	2.1	2.0	2.0	2.9	2.3	2.5	2.5	-1.4	1.6	1.9	2.0	2.4
Other serious medical condition/disability diagnosed by doctor	1.9	2.5	5.2	-1.5	-1.6	-0.1	-1.4	-2.3	-1.6	-1.7	-1.8	-1.4	-1.5	-1.4	-1.5	-0.8	-1.3	1.8	-1.2	-2.1	-2.2	-1.2
Medication: Ramipril	1.9	2.4	11.2	-1.4	-1.4	-1.8	-1.4	-3.3	-1.4	-1.6	-1.7	-1.3	-1.4	-1.7	-1.5	-0.3	-1.2	2.0	-0.8	-0.8	-1.5	-0.5
Birth weight of first child	1.9	3.4	9.4	1.8	1.9	3.1	1.9	1.9	1.9	1.8	2.0	2.3	1.8	2.2	1.9	1.5	1.8	-1.2	1.5	0.5	1.6	1.2
Alcohol intake frequency.	1.9	4.4	8.8	2.3	2.5	1.6	2.3	1.8	2.5	2.8	1.9	2.2	2.3	3.0	2.5	1.8	2.3	-1.9	1.9	0.4	1.3	1.0
Number of full brothers	1.8	2.2	6.2	1.6	1.4	2.5	1.7	1.4	1.5	1.6	1.8	2.0	1.7	1.7	1.4	-0.2	1.3	-1.9	0.8	0.2	0.9	0.3
Alzheimer’s Disease (in father)	1.7	1.8	3.0	-1.7	-1.7	0.1	-1.7	-1.1	-1.7	-1.6	-1.3	-1.6	-1.7	-1.5	-1.7	-1.1	-1.6	0.2	-1.3	-0.1	-1.0	-0.7
Schizophrenia (2014)	1.7	3.8	5.8	-2.3	-2.4	2.3	-2.1	-1.9	-2.2	-2.0	-2.2	-1.8	-2.3	-1.3	-2.4	-2.2	-2.0	1.6	-1.5	-1.0	-1.6	-0.8
Impedance of leg (right)	1.7	8.2	17.2	-3.5	-3.3	-1.4	-3.5	-1.9	-3.4	-3.3	-3.5	-4.2	-3.6	-2.8	-3.4	-2.6	-3.0	2.1	-1.9	-1.2	-2.0	-1.2
Qualifications: None of the above	1.7	3.7	8.8	-1.7	-1.7	-1.1	-1.7	-1.4	-1.6	-1.4	-1.7	-1.1	-1.6	-1.8	-1.7	-2.5	-1.6	2.1	-1.9	-3.0	-2.7	-2.8
Qualifications: O levels/GCSEs or equivalent	1.7	2.6	6.6	1.6	1.4	-0.6	1.7	0.9	1.4	1.0	1.2	1.1	1.6	1.3	1.5	2.3	1.4	-1.6	1.8	2.6	1.9	2.5
Schizophrenia vs Biploar Disorder	1.6	2.1	6.1	-1.5	-1.5	1.8	-1.3	-1.2	-1.3	-1.3	-1.2	-0.7	-1.4	-0.5	-1.5	-1.4	-1.4	2.0	-1.2	-2.5	-1.4	-1.4
Mouth/teeth dental problems: Bleeding gums	1.6	2.0	9.0	-1.4	-1.3	0.4	-1.3	-0.9	-1.4	-1.3	-1.1	-0.9	-1.3	-0.7	-1.4	-1.4	-1.3	0.4	-3.0	-0.9	-2.0	-2.3
Birth weight	1.6	3.5	23.8	1.6	1.6	4.9	1.8	1.7	1.6	1.5	1.7	2.6	1.6	2.0	1.6	0.8	1.4	-2.3	0.1	0.3	0.4	0.0
Health satisfaction	1.6	2.1	3.2	-1.4	-1.3	-1.3	-1.6	-1.5	-1.4	-1.4	-1.6	-1.7	-1.5	-1.3	-1.4	-1.6	-1.4	1.3	-1.0	-1.5	-1.3	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	2.0	4.9	-1.5	-1.8	-0.2	-1.3	-0.9	-1.7	-1.9	-1.4	-1.4	-1.4	-2.2	-1.8	0.2	-1.8	1.9	-0.5	1.0	0.1	0.5
Handedness (chirality/laterality): Left-handed	1.6	1.9	3.6	1.6	1.8	0.6	1.5	-0.7	1.7	1.6	1.8	1.5	1.5	1.9	1.7	1.3	1.9	-1.2	0.7	-0.3	-0.4	0.5
Cardiovascular Disease	1.5	5.0	22.8	-1.8	-1.9	-2.0	-1.8	-4.8	-1.9	-2.0	-2.1	-2.2	-1.7	-2.2	-1.9	-1.2	-1.4	2.4	-0.7	-2.6	-3.2	-1.7
Hayfever, allergic rhinitis or eczema	1.5	3.3	9.3	-2.3	-2.0	-0.2	-2.3	1.2	-2.1	-2.0	-3.0	-2.1	-2.4	-2.2	-2.1	-1.1	-1.9	1.0	-0.5	-0.8	-1.3	-0.7
Headache pain in last month	1.5	2.6	6.1	1.8	1.6	2.5	1.9	-0.5	1.8	1.6	1.5	2.2	1.9	1.5	1.7	1.7	1.9	-1.6	0.8	0.7	0.0	0.9
Average weekly red wine intake	1.5	2.2	8.5	-1.7	-1.6	-1.6	-1.7	-0.6	-1.7	-1.8	-1.5	-1.4	-1.8	-1.7	-1.6	-0.1	-1.8	2.9	0.3	-0.0	0.2	0.1
Mother’s age at death	1.5	1.9	4.5	1.3	1.4	-0.2	1.3	2.1	1.4	1.6	1.6	1.0	1.3	1.1	1.3	0.6	1.1	-1.3	1.2	1.6	2.0	1.2
Heart disease (siblings)	1.5	1.8	3.5	-1.3	-1.6	-1.2	-1.3	-1.8	-1.5	-1.7	-1.2	-1.7	-1.2	-1.9	-1.7	-0.7	-1.5	1.0	-1.0	-0.2	-0.9	-0.5
Crohns Disease (2017)	1.4	3.0	6.6	-1.9	-1.8	-1.7	-2.0	-1.0	-1.8	-1.8	-1.6	-2.3	-1.9	-2.0	-1.9	-1.8	-1.9	2.6	-1.4	-0.6	-0.4	-1.1
Number of treatments/medications taken	1.4	2.6	7.1	-1.8	-1.5	-0.1	-1.9	-2.7	-1.6	-1.5	-1.8	-1.7	-1.9	-1.4	-1.6	-1.0	-1.4	1.6	-1.1	-1.2	-2.0	-1.3
Impedance of leg (left)	1.4	6.6	14.0	-3.1	-2.9	-1.4	-3.2	-1.5	-3.0	-2.9	-3.3	-3.7	-3.3	-2.4	-3.1	-2.5	-2.7	1.5	-2.0	-1.0	-1.8	-1.1
Falls in the last year	1.4	1.9	4.5	1.4	1.5	2.1	1.4	-1.5	1.5	1.6	1.6	1.6	1.4	1.8	1.5	0.8	1.5	-1.8	0.3	0.3	-0.1	-0.1
Depression (self-reported)	1.4	1.7	5.1	-1.2	-1.1	0.8	-1.2	-1.5	-1.2	-1.2	-0.7	-1.3	-1.2	-0.7	-1.2	-1.6	-1.0	-0.2	-2.3	-1.1	-1.9	-1.9
Leg fat percentage (right)	1.4	5.2	9.4	-2.1	-2.3	-0.5	-2.0	-2.9	-2.2	-2.2	-2.4	-2.4	-1.9	-2.0	-2.3	-2.8	-2.2	2.6	-1.7	-3.1	-2.1	-2.4
Heel T-Score	1.3	10.2	34.0	3.0	3.0	5.8	3.4	2.8	2.9	2.8	3.1	4.4	3.2	4.2	3.1	2.9	2.6	-2.1	2.3	2.3	2.8	1.8
Medication: Co-codamol	1.3	1.5	4.3	1.0	1.0	2.1	1.1	-1.6	1.0	0.9	1.2	1.5	1.1	1.2	1.0	2.0	1.6	0.0	0.7	-0.4	-0.7	1.3
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.6	1.2	1.7	0.7	1.0	-0.9	1.5	1.8	1.0	1.0	1.0	1.9	1.5	0.7	1.8	-1.8	-0.1	0.3	-0.4	0.2
Systolic Blood Pressure	1.2	5.9	18.4	-2.0	-1.9	-4.3	-2.3	-2.9	-2.0	-1.9	-2.7	-2.9	-2.1	-3.1	-2.0	-1.9	-1.6	2.4	-1.7	-2.2	-2.8	-1.9
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.9	1.3	1.3	1.5	1.4	0.3	1.3	1.3	1.0	1.7	1.4	1.2	1.3	1.2	1.2	-0.9	0.6	0.6	0.6	0.4
Mouth/teeth dental problems	1.2	1.9	8.6	0.7	0.7	-1.2	0.6	1.6	0.7	0.7	0.6	0.1	0.6	0.2	0.7	0.9	0.6	0.9	2.9	1.6	2.6	2.8
Lung cancer (father)	1.2	1.5	6.8	-0.6	-0.8	0.9	-0.5	-2.4	-0.7	-0.7	-1.0	-0.4	-0.6	-0.8	-0.8	-0.7	-0.4	-1.5	-1.8	-0.7	-2.6	-1.6
Medication: Ventolin 100micrograms inhaler	1.2	1.6	4.2	1.0	0.8	-0.9	1.1	1.9	0.9	0.6	0.6	0.6	1.1	0.4	0.9	2.0	0.6	0.2	1.9	1.8	2.0	1.9
Pulse wave peak to peak time	1.2	1.4	3.4	1.1	1.3	1.8	1.2	1.1	1.2	1.2	1.3	1.6	1.2	1.7	1.3	1.2	0.9	-0.2	0.9	0.7	1.0	0.5
Medication: Allopurinol	1.2	1.6	3.6	-1.1	-1.4	-1.0	-1.0	-1.8	-1.3	-1.5	-1.4	-0.7	-1.0	-1.9	-1.3	-0.7	-1.3	1.6	-1.1	-1.0	-1.2	-1.1
Breast cancer (self-reported)	1.2	1.5	3.5	1.1	1.2	0.2	1.1	1.0	1.2	1.1	1.6	1.3	1.0	1.0	1.3	1.3	0.9	-0.0	1.9	1.4	1.7	1.3
Diastolic blood pressure, automated reading	1.2	3.7	11.4	-1.1	-1.1	-3.4	-1.3	-2.6	-1.1	-1.2	-1.1	-2.1	-1.1	-2.2	-1.1	-2.1	-0.9	1.1	-1.9	-2.9	-2.8	-2.4
Cholesterol lowering medication	1.2	1.8	3.0	-1.4	-1.3	0.7	-1.4	-1.4	-1.4	-1.3	-1.7	-1.7	-1.4	-1.5	-1.4	-1.2	-1.4	-0.0	-1.2	-0.7	-1.4	-1.6
Bipolar Disorder or Schizophrenia	1.1	2.6	4.7	-2.0	-2.2	0.5	-1.9	-1.6	-2.0	-1.9	-2.2	-2.0	-1.9	-1.5	-2.1	-1.3	-1.9	1.2	-0.7	0.3	-0.9	0.0
Age at First Birth	1.1	1.7	6.1	0.5	0.5	-2.2	0.4	0.8	0.4	0.1	0.5	0.2	0.4	0.0	0.5	2.5	0.4	0.8	1.5	2.4	2.1	2.3
Coronary Artery Disease (CAD)	1.1	1.3	5.7	-0.8	-1.2	-0.1	-0.8	-1.0	-1.0	-0.8	-0.9	-0.9	-0.7	-0.5	-0.7	-1.5	-1.4	1.3	-0.1	-2.4	-0.9	-1.7
Current tobacco smoking	1.1	1.8	3.3	-1.4	-1.5	0.8	-1.2	-1.8	-1.4	-1.5	-0.9	-0.8	-1.3	-1.4	-1.5	-1.7	-1.4	1.3	-1.3	-1.4	-1.1	-1.3
Serious illness, injury or assault to yourself	1.1	1.3	3.0	-0.8	-1.1	-1.7	-0.8	-1.4	-1.0	-1.0	-0.6	-1.1	-0.8	-1.3	-1.1	-1.2	-1.0	1.2	-1.0	-1.6	-1.2	-1.4
Pulse wave reflection index	1.1	1.4	3.1	-1.3	-1.4	-1.4	-1.3	-1.1	-1.3	-1.4	-1.2	-1.8	-1.2	-1.5	-1.4	-0.9	-1.1	0.9	-0.3	-0.2	-0.8	-0.2
Gout (self-reported)	1.1	1.5	3.3	-1.0	-1.3	-1.4	-1.0	-1.3	-1.2	-1.3	-1.0	-0.8	-1.0	-1.8	-1.2	-1.1	-1.1	1.8	-1.0	-1.5	-1.1	-0.9
Family relationship satisfaction	1.1	1.3	5.6	0.8	1.0	2.4	0.9	2.0	1.0	1.1	0.8	0.9	0.9	1.2	1.0	0.1	1.0	-1.4	0.5	0.7	1.4	0.7
Medication for cholesterol	1.1	1.7	4.2	1.2	1.2	0.9	1.2	2.1	1.2	1.2	1.8	1.7	1.2	1.1	1.3	1.1	1.1	-0.1	1.4	0.8	2.0	1.4
Leg fat percentage (left)	1.1	4.0	8.2	-1.7	-1.9	-0.5	-1.6	-2.6	-1.8	-1.8	-2.1	-2.0	-1.5	-1.6	-1.9	-2.8	-1.8	2.1	-1.9	-2.9	-2.0	-2.4
Schizophrenia (2018)	1.0	2.0	3.2	-1.6	-1.8	1.4	-1.5	-1.5	-1.6	-1.6	-1.7	-1.4	-1.5	-1.2	-1.7	-1.5	-1.5	1.1	-1.2	-0.6	-1.2	-0.5
Ovarian Cancer	1.0	1.3	6.1	1.1	1.1	2.5	1.2	0.4	1.1	1.1	1.0	1.4	1.0	0.9	1.1	-0.2	1.2	-1.4	-0.7	-0.8	-0.4	-0.8
Ulcerative Colitis	1.0	1.4	3.1	-1.5	-1.4	-0.2	-1.6	-0.1	-1.4	-1.2	-1.5	-1.8	-1.5	-0.8	-1.4	-1.2	-1.6	1.3	-0.8	0.3	-0.2	-0.8
Stomach or abdominal pain in last month	1.0	1.2	2.8	1.2	1.0	1.7	1.3	0.9	1.0	0.9	1.3	1.7	1.2	1.1	1.1	0.6	1.0	-1.7	-1.0	0.3	-0.3	-0.4
Age at first live birth	1.0	1.7	10.5	0.4	0.5	-1.4	0.2	3.2	0.5	0.5	0.2	-0.0	0.2	0.0	0.5	1.0	0.2	-0.1	2.3	1.7	2.5	1.9
Overall health rating	1.0	2.0	6.2	-1.3	-1.3	0.1	-1.3	-2.5	-1.3	-1.2	-1.2	-1.2	-1.2	-1.3	-1.3	-1.6	-1.1	1.1	-0.9	-2.0	-1.9	-1.7
Hypertension (Self-reported)	1.0	2.9	15.3	-1.4	-1.4	-0.5	-1.5	-3.9	-1.4	-1.6	-1.5	-1.7	-1.4	-1.7	-1.5	-0.6	-1.1	2.7	-0.2	-1.6	-2.2	-0.8
Number of self-reported non-cancer illnesses	1.0	1.7	4.8	-1.1	-1.2	-1.4	-1.2	-2.2	-1.1	-1.1	-1.5	-1.5	-1.1	-1.4	-1.1	-1.0	-1.0	1.6	0.1	-1.7	-1.5	-0.7
Medication: Blood pressure	1.0	1.9	6.1	-1.2	-1.2	-1.3	-1.3	-2.5	-1.2	-1.2	-1.9	-1.8	-1.2	-1.3	-1.2	-1.0	-0.9	1.1	-0.5	-1.5	-1.9	-0.7
Ever had prostate specific antigen (PSA) test	1.0	1.2	5.8	-0.9	-1.2	-1.0	-0.7	-0.8	-1.0	-1.2	-0.6	-0.7	-0.7	-1.8	-1.1	0.3	-1.3	2.4	0.8	0.7	0.6	0.8
Worry (Nagel 2018)	0.9	1.9	6.1	-1.0	-1.1	0.4	-1.0	-1.8	-1.1	-1.1	-1.3	-1.3	-1.0	-1.2	-1.1	-1.7	-1.0	0.9	-1.0	-2.5	-2.0	-1.9
Allergy or Eczema	0.9	2.3	7.8	-1.9	-1.7	0.5	-1.9	1.1	-1.8	-1.6	-2.8	-1.7	-1.9	-1.8	-1.7	-0.6	-1.4	0.6	-0.5	-0.6	-1.4	-0.4
Average weekly spirits intake	0.9	1.1	6.0	-0.9	-0.7	0.1	-1.0	-0.8	-0.8	-0.8	-0.8	-0.4	-0.8	-0.4	-0.7	-0.8	-0.7	0.5	-2.4	-1.0	-1.7	-1.8
Severe depression (siblings)	0.9	1.0	4.2	0.9	0.9	2.1	1.0	-1.2	0.9	0.9	1.3	0.8	0.9	1.2	0.8	0.0	1.0	-1.6	-0.7	0.1	-0.5	-0.3
Average weekly fortified wine intake	0.9	1.0	2.7	-1.2	-0.9	0.6	-1.3	-0.2	-1.0	-0.8	-1.1	-0.9	-1.3	-0.8	-1.0	-1.0	-0.9	1.6	-0.7	-1.3	-0.8	-0.8
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.5	0.7	0.3	-1.6	0.8	0.0	0.5	0.1	1.2	0.6	0.8	0.3	0.4	1.5	0.3	0.6	1.7	1.9	1.3	1.8
Medication: Atenolol	0.9	1.1	4.2	0.8	1.1	-0.0	0.6	-1.0	0.9	0.9	0.6	0.6	0.8	0.9	0.9	1.9	1.4	0.2	1.6	1.0	0.7	2.0
Financial difficulties in last 2 years	0.9	1.2	2.2	1.4	1.2	1.1	1.5	-0.7	1.2	1.1	1.3	1.2	1.4	1.0	1.2	0.9	1.4	-1.2	0.4	0.4	-0.0	0.7
Breastfed as a baby	0.9	1.1	4.8	0.9	0.8	-1.0	0.9	2.2	0.8	0.6	1.1	0.7	0.9	0.1	0.8	0.9	0.8	-1.0	-0.2	1.8	1.2	1.2
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	4.5	-1.2	-0.9	-1.8	-1.4	-2.1	-1.0	-0.8	-1.2	-1.8	-1.4	-1.0	-1.0	-1.5	-0.7	0.5	-1.9	-0.4	-1.6	-0.9
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.2	1.1	1.3	0.1	0.9	0.3	1.2	1.1	1.4	0.8	0.9	1.0	1.2	0.8	1.4	-1.2	0.7	1.5	0.6	1.1
Qualifications: College or University degree	0.9	2.7	9.3	1.6	1.3	-0.2	1.6	2.3	1.4	1.2	1.5	1.0	1.7	0.8	1.4	1.6	0.9	-1.1	1.8	2.6	3.0	1.9
Eye problems/disorders: Cataract	0.9	1.1	2.5	-1.2	-1.0	-0.2	-1.3	-1.2	-1.1	-1.0	-0.8	-0.6	-1.3	-0.6	-1.0	-1.0	-0.8	1.0	-1.6	-0.6	-1.4	-1.0
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.5	1.1	1.2	-1.1	1.0	1.4	1.2	1.3	1.2	1.0	1.1	1.3	1.2	0.5	1.0	-1.6	0.7	0.7	0.8	0.4
Hypothyroidism (self reported)	0.8	1.8	5.6	-1.1	-0.9	-1.4	-1.4	-2.4	-1.0	-0.7	-1.1	-1.8	-1.3	-0.9	-1.0	-1.7	-0.7	0.2	-2.0	-0.6	-1.8	-1.1
Ever used hormone-replacement therapy (HRT)	0.8	1.0	5.5	-0.7	-0.5	0.4	-0.7	-0.1	-0.5	-0.3	-0.0	-0.3	-0.7	0.1	-0.6	-1.4	-0.6	-1.4	-2.3	-0.0	-1.5	-1.9
Vitamin and mineral supplements	0.8	1.1	5.2	-1.1	-1.1	-0.3	-1.0	-2.3	-1.1	-1.2	-0.7	-0.8	-1.1	-1.3	-1.1	-0.1	-0.9	1.6	-0.9	0.2	-0.8	0.0
High blood pressure	0.8	2.4	15.6	-1.1	-1.1	-0.6	-1.2	-4.0	-1.1	-1.2	-1.2	-1.5	-1.1	-1.5	-1.1	-0.2	-0.7	2.8	0.3	-1.4	-1.8	-0.3
Chronic bronchitis/emphysema (father)	0.8	1.0	2.5	-1.0	-1.2	-0.6	-0.9	-0.8	-1.2	-1.3	-1.2	-1.6	-1.0	-1.5	-1.1	-0.9	-0.9	-0.1	0.3	-0.5	-1.0	0.1
Heart attack	0.8	1.0	8.0	0.3	0.3	-1.8	0.2	-2.8	0.4	0.3	0.5	0.1	0.2	-0.1	0.2	1.5	0.9	1.1	0.8	0.7	-0.4	1.4
Allergy	0.8	1.9	4.9	1.5	1.6	-0.2	1.4	-1.8	1.6	1.4	2.2	1.3	1.5	1.8	1.5	1.5	1.5	0.0	0.5	0.9	1.2	1.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.2	-0.6	-0.4	-1.4	-0.8	1.8	-0.5	-0.6	-1.5	-1.0	-0.7	-0.6	-0.4	0.8	-0.6	0.5	1.4	1.3	1.3	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	4.2	1.1	1.2	0.7	0.9	-0.8	1.1	1.2	0.9	0.7	1.0	1.2	1.2	1.3	1.6	-1.0	2.0	0.5	0.3	1.7
Pulse wave Arterial Stiffness index	0.8	0.9	2.6	-0.9	-1.0	-1.6	-0.9	-1.1	-0.9	-0.9	-1.0	-1.3	-0.9	-1.4	-1.0	-0.9	-0.6	-0.0	-0.7	-0.5	-1.0	-0.3
Exposure to tobacco smoke at home	0.8	0.9	2.6	-0.9	-0.9	-0.2	-0.9	-1.2	-0.9	-0.8	-0.4	-1.1	-0.7	-0.6	-0.9	-1.1	-1.1	0.7	-1.5	-0.6	-1.1	-1.6
Body fat percentage	0.8	3.0	7.6	-1.2	-1.5	0.7	-1.1	-2.8	-1.3	-1.3	-1.6	-1.4	-0.9	-0.9	-1.4	-2.3	-1.3	1.6	-2.4	-2.7	-2.1	-2.4
Migraine (self-reported)	0.8	1.0	5.1	1.0	1.0	2.3	1.1	-0.2	1.0	0.9	0.7	1.1	1.0	1.3	1.0	0.0	1.1	-1.1	0.2	-0.8	-0.6	-0.1
Chest pain or discomfort	0.8	1.2	2.9	1.1	0.9	0.8	1.1	0.3	1.0	0.7	1.2	1.3	1.1	0.5	1.0	1.6	1.2	-1.2	1.3	1.2	0.7	1.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.5	1.1	0.8	1.8	1.3	-1.4	0.9	0.7	0.7	1.6	1.2	1.3	0.9	1.4	1.0	-1.9	-0.8	0.8	-0.7	-0.2
Smoking status: Current	0.8	1.3	2.4	-1.1	-1.2	0.7	-1.0	-1.6	-1.2	-1.3	-0.6	-0.6	-1.0	-1.2	-1.3	-1.3	-1.2	1.4	-1.0	-1.1	-0.7	-1.1
Heart attack/myocardial infarction (self-reported)	0.8	1.1	7.2	0.4	0.4	-2.0	0.2	-2.7	0.4	0.3	0.6	0.1	0.3	-0.2	0.3	1.6	0.9	1.1	0.7	0.9	-0.2	1.4
HbA1C	0.7	0.8	2.9	0.8	0.5	1.0	1.0	1.7	0.8	0.8	0.5	0.9	1.0	0.8	0.8	0.4	0.4	-1.1	0.8	0.8	1.1	0.3
Neuroticism (2016)	0.7	1.0	2.7	1.1	0.9	1.6	1.2	-0.1	1.0	1.0	0.8	1.2	1.2	1.1	1.0	0.5	1.3	-1.3	0.7	-0.3	-0.5	0.6
Height	0.7	12.8	20.2	3.8	3.9	4.5	3.9	0.6	3.9	4.0	4.0	3.5	3.7	3.3	3.9	3.7	4.3	-2.9	2.9	2.9	2.2	4.0
Chronotype (morning person)	0.7	1.7	12.4	-0.9	-0.8	-3.5	-1.1	0.4	-0.9	-1.0	-1.8	-1.7	-0.9	-1.2	-0.9	-0.1	-0.8	1.8	0.6	0.3	0.8	0.6
Hearing difficulty/problems: Yes	0.7	1.0	4.4	-0.8	-0.9	0.4	-0.7	-2.1	-0.9	-1.0	-1.2	-0.9	-0.8	-1.0	-0.9	-0.8	-0.7	1.4	0.3	-1.4	-0.9	-0.1
Trunk fat percentage	0.7	2.7	7.6	-1.1	-1.4	1.3	-0.9	-2.8	-1.2	-1.3	-1.4	-1.3	-0.9	-0.8	-1.3	-2.1	-1.2	1.5	-2.4	-2.4	-2.0	-2.2
Townsend deprivation index at recruitment	0.7	1.0	2.6	1.0	0.8	1.3	1.2	-1.6	0.9	0.7	1.6	1.4	1.1	0.8	0.9	0.4	0.9	0.7	0.5	-1.0	-0.4	0.1
Number of incorrect matches in round	0.7	1.1	4.7	-1.0	-1.1	-1.8	-0.9	-0.6	-1.0	-1.2	-0.6	-1.2	-1.0	-0.8	-1.1	0.1	-1.5	2.2	0.6	0.0	0.7	-0.1
Had other major operations	0.7	0.8	3.0	0.7	0.9	-1.0	0.5	0.5	0.8	0.9	0.4	0.1	0.6	0.7	0.8	1.4	0.7	-0.4	1.2	1.7	1.3	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	4.0	0.5	0.7	-0.2	0.5	-0.4	0.6	0.5	0.9	0.7	0.4	0.6	0.7	1.8	0.9	-0.3	0.1	2.0	0.6	1.5
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.2	-0.9	-1.1	-0.1	-0.8	-1.1	-1.0	-0.9	-0.5	-1.0	-0.7	-0.5	-1.1	-1.5	-1.2	0.9	-0.8	-0.9	-0.4	-1.1
Eye problems/disorders: Glaucoma	0.7	0.8	2.4	-1.0	-0.9	-0.8	-1.0	-0.4	-0.9	-0.8	-0.3	-0.8	-1.0	-0.9	-0.9	-1.0	-0.8	1.3	0.8	-1.5	-0.4	-0.4
Medication: Atorvastatin	0.7	0.9	3.1	-1.0	-0.6	-1.1	-1.2	-1.7	-0.7	-0.5	-0.9	-1.2	-1.1	-0.5	-0.7	-0.8	-0.7	0.9	-1.1	-0.2	-0.6	-0.9
Basal cell carcinoma (self-reported)	0.7	0.9	8.1	0.3	0.2	2.9	0.4	-0.2	0.2	0.2	1.0	0.8	0.3	0.6	0.2	0.2	0.4	0.4	1.3	0.3	1.3	1.5
Bipolar Disorder (2018)	0.6	1.0	1.8	-1.1	-1.2	-1.0	-1.1	-0.7	-1.1	-1.0	-1.3	-1.4	-1.1	-1.0	-1.2	-0.2	-1.1	0.6	0.4	1.3	-0.0	0.7
Reaction Time	0.6	1.1	6.3	-0.5	-0.5	-2.5	-0.7	1.6	-0.5	-0.3	-0.4	-1.2	-0.5	-0.9	-0.5	0.1	-0.8	0.6	1.1	1.4	1.7	1.1
LDL Cholesterol	0.6	1.0	3.5	-1.0	-0.9	-1.9	-1.0	-1.5	-0.9	-1.0	-1.0	-0.9	-1.0	-0.7	-0.8	0.4	-0.6	1.2	0.7	0.6	-0.2	1.0
Rheumatoid Arthritis	0.6	0.8	2.2	-1.0	-1.0	0.3	-0.9	-0.6	-1.0	-0.9	-0.6	-0.7	-0.9	-0.5	-1.0	-1.1	-1.0	0.9	-0.6	-1.5	-0.8	-1.1
Relative age of first facial hair	0.6	1.2	6.1	0.8	0.9	-0.3	0.8	2.5	0.8	0.8	0.4	1.1	0.8	0.8	0.8	0.4	0.7	-2.1	-1.2	1.7	0.9	0.2
Father’s age at death	0.6	0.8	5.8	0.4	0.4	2.4	0.5	1.2	0.3	0.2	1.2	1.2	0.4	0.5	0.4	0.8	0.4	-0.6	-0.2	0.9	0.7	0.7
Worrier / anxious feelings	0.6	1.2	2.5	-1.0	-1.1	-0.9	-1.1	-1.5	-1.1	-1.0	-1.2	-1.1	-1.0	-1.2	-1.1	-0.8	-0.9	0.8	-0.9	-1.1	-1.6	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	13.5	0.9	1.0	3.7	1.0	-1.5	0.9	0.8	1.4	1.4	0.9	1.4	1.0	1.5	1.3	-0.4	-0.6	-0.3	-1.1	0.1
Angina (self-reported)	0.6	0.8	2.2	0.9	0.9	0.1	0.8	-0.7	0.9	0.9	0.9	0.6	0.9	1.1	0.8	0.8	0.9	-1.5	0.1	1.5	0.4	0.4
Leg fat mass (right)	0.6	2.5	7.4	-1.1	-1.3	0.0	-1.0	-2.7	-1.2	-1.2	-1.4	-1.2	-0.9	-1.3	-1.3	-1.8	-1.1	2.1	-1.4	-2.7	-1.9	-1.8
Number of full sisters	0.6	0.7	2.8	-0.8	-0.9	0.2	-0.8	-0.3	-0.8	-0.6	-0.3	-0.4	-0.7	-1.1	-0.9	-1.7	-0.7	0.3	-1.4	-0.8	-0.7	-0.7
Supplements: Vitamin C	0.6	0.7	2.2	0.8	0.7	-1.0	0.8	0.7	0.8	0.9	0.8	0.5	0.8	0.3	0.8	0.4	0.5	-1.5	1.1	1.4	0.8	0.4
Fractured/broken bones in last 5 years	0.6	0.8	2.6	1.0	0.7	-0.1	1.1	0.3	0.8	0.7	1.2	0.6	1.0	0.7	0.8	1.0	0.6	-0.5	1.6	0.8	1.4	1.0
Neuroticism (Nagel 2018)	0.5	1.2	5.4	-0.3	-0.4	2.2	-0.2	-2.3	-0.4	-0.4	-0.5	-0.3	-0.2	-0.3	-0.3	-1.1	-0.2	-0.3	-0.9	-2.0	-1.9	-1.4
Type 2 Diabetes (T2D) (2018)	0.5	1.0	5.2	-0.9	-0.8	-2.3	-1.0	-0.8	-0.8	-0.7	-1.0	-1.4	-0.9	-1.2	-0.8	-0.7	-0.6	0.3	-1.1	-0.2	-0.6	-0.5
Lung FEV1/FVC ratio	0.5	2.6	6.7	1.8	1.8	1.6	1.8	1.5	1.7	1.9	2.2	2.0	1.9	2.6	1.7	0.8	1.4	-1.5	-0.3	0.0	1.1	-0.3
Sensitivity / hurt feelings	0.5	0.9	6.4	0.1	0.0	2.5	0.2	-0.3	0.0	0.2	-0.2	0.4	0.2	0.2	0.1	-1.0	0.0	-0.5	-1.1	-1.4	-1.2	-1.9
Ever had hysterectomy (womb removed)	0.5	0.6	2.5	1.0	0.8	-0.1	1.0	-0.1	0.8	0.7	0.5	0.7	1.0	1.1	0.8	0.8	0.7	-1.6	0.6	0.4	-0.3	0.0
Angina	0.5	0.6	2.6	0.8	0.8	-0.1	0.6	-0.7	0.8	0.8	0.8	0.4	0.8	1.0	0.7	0.6	0.8	-1.6	-0.1	1.5	0.3	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	3.7	-0.0	0.1	1.1	-0.1	-1.3	0.0	0.1	-0.4	-0.2	-0.1	0.2	0.1	-0.8	0.7	-1.5	-0.9	-1.3	-1.9	-0.5
Multivitamins +/- minerals	0.5	0.6	4.6	0.6	0.8	0.9	0.5	2.1	0.7	0.9	0.4	0.4	0.6	1.2	0.7	-0.0	0.5	-1.1	0.3	-0.2	0.5	-0.3
Supplements: Glucosamine	0.5	0.7	1.5	0.7	0.8	1.2	0.7	0.2	0.7	0.6	1.0	1.1	0.7	0.9	0.8	1.2	0.8	-0.3	1.0	0.7	0.3	1.2
Medication: Levothyroxine sodium	0.5	0.9	7.6	-0.6	-0.4	-1.0	-0.7	-2.8	-0.4	-0.4	-0.7	-0.7	-0.7	-0.0	-0.5	-0.4	-0.1	0.3	-1.2	-0.5	-1.8	-0.6
Alcohol usually taken with meals	0.5	0.8	3.0	0.3	0.1	-1.7	0.3	1.2	0.1	0.1	0.4	-0.3	0.3	-0.3	0.1	1.3	-0.2	0.2	1.1	1.6	1.5	1.3
Hearing difficulty/problems with background noise	0.5	0.8	3.3	-0.7	-0.9	1.2	-0.5	-1.6	-0.9	-1.3	-0.7	-0.1	-0.7	-0.7	-0.8	0.2	-1.0	1.8	0.5	-0.7	-0.2	-0.1
Pain all over the body in last month	0.5	0.5	2.8	0.5	0.5	1.7	0.6	-1.2	0.5	0.4	1.1	0.8	0.6	0.5	0.5	0.4	0.7	-0.6	0.2	-0.5	-0.7	-0.2
Diabetes (self-reported)	0.5	0.8	4.7	-0.5	-0.8	-2.2	-0.5	-0.1	-0.7	-0.6	-0.8	-0.9	-0.4	-1.3	-0.7	-0.8	-0.9	0.3	-0.6	-0.8	-0.2	-1.1
Medication: Simvastatin	0.5	0.7	1.8	-1.0	-0.9	0.6	-0.9	-1.1	-1.0	-0.9	-0.8	-0.6	-0.9	-1.3	-1.0	-0.6	-1.0	0.5	-0.3	-0.5	-0.8	-0.9
Pulse rate	0.5	0.8	2.4	1.0	0.9	0.3	1.0	0.7	1.0	1.3	1.2	1.1	1.0	0.6	1.0	-0.5	0.9	-1.6	0.1	-1.0	0.1	-0.5
Exposure to tobacco smoke outside home	0.5	0.7	3.9	-0.3	-0.4	1.2	-0.2	-0.5	-0.3	-0.2	0.1	0.2	-0.2	-0.2	-0.4	-1.4	-0.6	0.3	-2.0	-1.1	-0.6	-1.7
Worry too long after embarrassment	0.5	0.9	2.9	1.1	0.9	1.0	1.3	-0.9	1.0	1.1	0.9	1.1	1.1	0.7	1.0	0.3	1.1	-1.7	0.2	-0.3	-0.5	-0.2
Medication: Blood pressure	0.5	0.8	11.0	-0.3	-0.1	0.1	-0.4	-3.3	-0.2	-0.1	0.1	-0.2	-0.3	-0.6	-0.2	0.5	0.3	1.6	0.2	-0.0	-0.7	0.5
Medication: Omeprazole	0.5	0.6	3.8	-0.0	-0.0	-0.8	-0.1	-1.5	-0.0	-0.2	0.5	-0.2	-0.1	-0.6	-0.0	0.7	0.4	-0.1	0.8	1.5	0.3	2.0
Mean time to correctly identify matches	0.5	0.9	4.1	0.2	0.1	-1.7	0.2	1.2	0.2	0.3	0.6	0.0	0.4	-0.0	0.2	1.1	-0.3	0.4	1.2	1.9	2.0	1.1
Whole body fat mass	0.5	2.0	7.2	-0.7	-0.9	0.7	-0.6	-2.6	-0.8	-0.9	-1.0	-0.8	-0.5	-0.8	-0.9	-1.6	-0.7	1.7	-1.8	-2.7	-1.9	-1.8
Suffer from ‘nerves’	0.5	0.8	4.6	-0.3	-0.6	1.9	-0.1	-1.1	-0.5	-0.6	-0.3	-0.2	-0.1	-0.7	-0.5	-1.3	-0.4	0.7	0.0	-2.1	-1.2	-1.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.5	0.7	0.9	0.1	0.6	0.5	0.9	1.0	0.5	0.2	0.6	1.2	0.8	0.6	0.8	-0.7	0.9	0.8	1.0	0.6
Leg fat-free mass (right)	0.5	2.9	5.9	2.1	2.0	1.8	2.1	-0.4	2.1	2.0	2.1	2.4	2.2	1.5	2.1	1.3	2.2	-0.5	0.6	-0.7	0.0	0.4
Arm fat percentage (left)	0.5	1.8	6.1	-0.6	-1.0	1.3	-0.5	-2.5	-0.9	-0.9	-1.1	-0.7	-0.4	-0.4	-0.9	-1.8	-0.9	0.8	-2.0	-2.1	-1.8	-2.1
Mood swings	0.5	0.9	3.2	-0.9	-0.8	1.5	-0.8	-1.8	-0.9	-0.9	-0.5	-0.7	-0.9	-0.6	-0.8	-1.5	-0.6	0.2	-0.1	-1.1	-1.1	-0.3
Ever had bowel cancer screening	0.5	0.6	2.5	-0.4	-0.4	0.8	-0.3	-0.6	-0.4	-0.4	-0.4	0.1	-0.3	-0.6	-0.3	-1.3	-0.3	0.2	-1.6	-1.1	-1.2	-1.2
Qualifications: nursing, teaching	0.5	0.7	2.8	1.0	0.9	0.3	1.0	0.5	1.0	1.0	1.0	0.7	1.0	1.3	1.0	0.2	0.7	-1.7	-0.1	0.5	0.4	-0.4
Leg predicted mass (right)	0.5	2.9	6.0	2.1	2.0	1.9	2.1	-0.4	2.1	2.0	2.1	2.4	2.1	1.5	2.1	1.3	2.2	-0.6	0.6	-0.6	0.0	0.4
Financial situation satisfaction	0.5	0.6	1.1	-0.8	-0.8	0.1	-0.8	-0.2	-0.8	-0.9	-1.0	-0.9	-0.8	-0.3	-0.9	-0.6	-0.8	1.1	-0.2	-1.1	-0.7	-0.8
Myopia	0.5	0.7	1.6	-0.8	-0.8	-0.3	-0.8	1.1	-0.8	-0.8	-1.1	-0.5	-0.8	-0.9	-0.8	-1.2	-1.1	1.3	-0.1	-0.6	0.8	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	3.6	-0.7	-0.6	-0.4	-0.7	-1.9	-0.7	-0.8	-0.1	-0.6	-0.7	-1.0	-0.6	0.4	-0.2	0.7	0.2	1.2	-0.1	1.5
Pain experienced in last month	0.5	0.9	2.4	-0.9	-0.9	-1.6	-0.9	1.2	-0.9	-0.9	-1.1	-0.4	-0.8	-0.9	-0.9	-0.8	-1.2	0.7	-1.4	-0.5	-0.0	-1.1
Impedance of whole body	0.5	2.3	5.5	-1.8	-1.6	0.7	-1.7	-0.9	-1.7	-1.6	-1.9	-2.3	-1.8	-0.7	-1.7	-1.7	-1.5	0.1	-2.0	-0.5	-1.2	-1.1
Leg fat mass (left)	0.5	2.0	6.7	-0.8	-1.1	-0.0	-0.8	-2.5	-0.9	-1.0	-1.2	-1.0	-0.7	-1.0	-1.0	-1.8	-0.9	1.8	-1.4	-2.6	-1.8	-1.8
Depression (Nagel 2018)	0.4	0.5	4.1	-0.3	-0.2	2.0	-0.2	-0.8	-0.3	-0.2	-0.6	-0.3	-0.3	0.2	-0.2	-0.7	0.1	-1.0	-0.8	-0.9	-1.3	-0.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	5.6	0.3	0.5	-0.7	0.3	2.4	0.5	0.5	0.0	0.0	0.3	0.4	0.4	1.0	0.5	-0.4	1.5	1.9	2.3	2.2
Alzheimer’s Disease (in mother)	0.4	0.4	2.5	0.5	0.7	-0.3	0.5	1.1	0.6	0.7	0.3	0.5	0.5	0.5	0.7	-0.6	0.6	-1.6	-0.6	-0.0	0.0	-0.2
Prostate Cancer	0.4	0.5	1.6	-0.8	-0.7	-0.3	-0.8	1.2	-0.6	-0.6	-0.3	-0.9	-0.8	-0.3	-0.7	-1.0	-0.8	1.0	-0.4	0.2	1.1	0.2
Bipolar Disorder (2011)	0.4	0.4	3.9	-0.1	-0.2	-0.3	-0.1	-0.3	-0.0	0.1	-0.2	-0.6	-0.1	0.1	-0.2	-0.2	-0.2	-1.3	-0.5	2.0	0.6	0.5
Fasting Glucose	0.4	0.5	3.6	0.6	0.4	-1.9	0.6	-0.5	0.6	0.5	0.2	0.4	0.7	-0.1	0.5	0.4	0.6	0.6	0.7	0.1	0.7	0.8
Waist Hip Ratio (WHR)	0.4	1.6	3.4	-1.4	-1.4	-0.4	-1.5	-1.6	-1.4	-1.3	-1.8	-1.8	-1.5	-1.4	-1.3	-0.9	-1.2	0.6	-0.3	-1.3	-1.1	-0.6
Hand grip strength (left)	0.4	1.1	4.3	0.5	0.4	-1.8	0.5	0.4	0.4	0.1	0.7	-0.1	0.5	-0.5	0.4	1.2	0.2	0.5	2.1	1.8	2.0	1.8
Medication for hormone replacement therapy	0.4	0.5	2.0	-0.4	-0.3	0.3	-0.4	-0.9	-0.3	-0.2	-0.0	-0.6	-0.4	0.1	-0.4	-0.8	-0.3	-1.0	-1.3	-0.1	-1.4	-1.2
Relative age voice broke	0.4	0.6	1.9	-0.7	-0.7	-0.9	-0.8	1.4	-0.7	-0.6	-1.1	-0.6	-0.7	-0.8	-0.6	-0.8	-0.8	-0.0	-0.9	0.7	0.3	-0.2
Body mass index (BMI)	0.4	1.6	5.7	-0.8	-1.0	0.0	-0.7	-2.0	-0.9	-0.9	-1.0	-0.6	-0.6	-1.0	-0.9	-1.8	-0.9	1.4	-1.4	-2.4	-1.7	-1.9
Trunk fat mass	0.4	1.7	7.5	-0.5	-0.8	1.2	-0.4	-2.7	-0.7	-0.8	-0.8	-0.6	-0.3	-0.5	-0.7	-1.4	-0.5	1.5	-1.8	-2.4	-1.8	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.4	0.5	0.6	2.1	0.5	0.1	0.5	0.7	0.2	0.2	0.4	0.7	0.6	-0.1	0.9	-1.7	0.2	-0.7	-0.8	-0.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.3	0.5	0.7	1.1	0.4	-0.5	0.6	0.5	0.7	0.2	0.4	0.5	0.7	0.3	0.8	-0.5	1.5	0.4	0.4	1.1
Illnesses of siblings	0.4	0.6	4.0	0.7	0.7	0.4	0.7	2.0	0.7	0.7	-0.0	1.2	0.6	0.5	0.8	0.9	0.6	-0.3	0.7	-0.1	0.7	0.5
Arm fat percentage (right)	0.4	1.5	6.0	-0.3	-0.8	1.6	-0.1	-2.5	-0.6	-0.6	-0.8	-0.4	-0.0	-0.0	-0.7	-1.6	-0.7	0.7	-1.7	-2.1	-1.6	-2.0
Time employed in main current job	0.4	0.4	1.1	-0.7	-0.9	0.5	-0.5	-0.1	-0.8	-0.8	-0.6	-0.3	-0.6	-1.1	-0.9	-0.4	-0.8	-0.0	-0.7	-0.3	-0.6	-0.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	9.5	0.9	1.0	3.1	0.9	-1.2	1.0	0.8	1.2	1.2	0.8	1.3	1.0	1.7	1.4	-0.0	0.3	-0.1	-0.3	1.0
Noisy workplace	0.4	0.5	2.3	0.4	0.4	-1.3	0.3	-1.5	0.4	0.2	0.4	-0.2	0.3	-0.2	0.4	1.1	0.7	0.5	0.6	0.4	-0.3	1.0
Prospective memory result	0.4	0.5	1.3	-0.5	-0.6	-1.1	-0.5	-0.7	-0.5	-0.4	-0.2	-0.8	-0.5	-0.3	-0.6	-1.1	-0.9	1.1	0.5	-0.9	-0.1	-0.9
Hair/balding pattern: Pattern 4	0.4	1.0	3.7	1.0	1.1	-0.8	0.9	0.8	1.1	1.2	0.6	0.1	1.0	0.7	1.1	0.6	1.1	-0.8	1.9	0.3	0.9	1.2
High blood pressure (siblings)	0.4	0.6	4.1	-0.5	-0.4	-0.3	-0.6	-2.0	-0.4	-0.3	0.3	-0.9	-0.6	0.1	-0.5	-0.9	-0.2	-0.5	-1.0	-0.2	-1.2	-0.8
Forced vital capacity (FVC), Best measure	0.4	1.5	11.5	0.8	0.7	3.4	0.9	-1.9	0.7	0.5	1.3	1.2	0.7	0.9	0.8	1.4	1.2	0.1	0.2	-0.7	-1.2	0.5
Emphysema/chronic bronchitis	0.4	0.5	4.3	-0.1	-0.1	0.8	-0.1	0.9	-0.2	-0.1	-0.4	-0.2	-0.1	-0.3	-0.2	0.2	-0.0	1.0	2.1	-0.5	0.7	1.1
Medication: Ibuprofen	0.4	0.5	2.4	-0.4	-0.1	0.5	-0.5	-0.4	-0.2	-0.0	0.0	-0.4	-0.5	0.4	-0.3	-1.5	-0.3	0.3	-1.1	-1.1	-0.6	-1.6
Medication: Seretide 50 evohaler	0.4	0.5	2.6	0.6	0.5	0.1	0.7	1.3	0.6	0.4	0.0	0.9	0.7	0.5	0.5	0.9	0.3	-0.2	1.6	0.2	0.7	0.4
Illnesses of father: Heart disease	0.4	0.5	5.9	-0.1	-0.4	1.4	0.1	-2.4	-0.3	-0.6	0.3	-0.3	0.0	0.1	-0.3	0.1	-0.2	0.6	0.7	-0.4	-0.2	0.5
Illnesses of siblings: Diabetes	0.4	0.5	2.2	0.7	0.7	1.5	0.7	0.6	0.8	1.0	0.7	0.5	0.7	0.7	0.7	-0.3	0.7	-0.9	0.7	0.1	0.4	0.1
Osteoarthritis (self-reported)	0.4	0.5	2.7	-0.4	-0.5	1.1	-0.3	-1.5	-0.4	-0.5	-0.6	0.1	-0.3	-0.2	-0.5	0.1	-0.2	0.3	-1.0	-0.5	-1.7	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.3	-0.8	-0.9	1.6	-0.7	-1.8	-0.8	-0.9	-0.1	-0.3	-0.8	-0.2	-0.8	-0.3	-0.6	0.8	-0.9	-1.1	-1.5	-0.8
Arm fat mass (left)	0.4	1.5	5.9	-0.4	-0.7	1.1	-0.3	-2.4	-0.6	-0.6	-0.7	-0.4	-0.2	-0.4	-0.6	-1.5	-0.5	0.9	-1.8	-2.2	-1.8	-1.9
Miserableness	0.4	0.6	3.4	0.5	0.5	1.8	0.6	-1.0	0.4	0.4	0.8	0.6	0.6	0.0	0.6	-0.3	0.8	-1.5	1.0	-0.5	-0.4	0.4
Illnesses of father: High blood pressure	0.4	0.5	3.1	0.2	0.1	1.1	0.2	-1.2	0.1	0.1	-0.0	-0.0	0.2	0.4	0.1	0.4	0.6	-1.8	-0.8	0.2	-1.6	-0.0
Unable to work because of sickness or disability	0.4	0.6	5.6	-0.4	-0.4	2.4	-0.3	-1.5	-0.4	-0.5	0.6	0.1	-0.5	-0.3	-0.4	0.1	-0.1	0.5	-0.5	-0.3	-0.5	0.3
Commuting to job workplace: Cycle	0.4	0.4	2.5	-0.4	-0.6	-1.6	-0.4	0.2	-0.5	-0.8	-0.3	-0.2	-0.2	-1.0	-0.6	0.2	-0.7	1.1	-0.6	0.6	0.6	0.2
Vascular/heart problems diagnosed by doctor	0.4	1.2	11.8	0.5	0.5	0.5	0.6	3.4	0.5	0.6	0.6	0.9	0.5	0.9	0.6	-0.1	0.1	-1.8	-0.2	1.1	1.6	0.2
Alcohol drinker status: Previous	0.4	0.4	2.8	-0.0	-0.0	1.7	0.0	-1.5	0.0	0.1	0.1	-0.0	0.0	0.3	-0.0	0.2	0.1	-0.4	-0.8	-0.6	-1.0	-0.7
Depressed Affect (Nagel 2018)	0.3	0.7	4.2	-0.4	-0.5	2.0	-0.2	-2.1	-0.5	-0.6	-0.2	-0.3	-0.3	-0.4	-0.4	-1.0	-0.3	0.0	0.4	-1.3	-0.9	-0.3
Alzheimer’s Disease (including proxy)	0.3	0.5	3.1	-0.3	-0.1	0.4	-0.4	0.8	-0.3	-0.2	-0.2	-0.2	-0.3	-0.2	-0.2	-1.0	-0.3	-1.3	-1.8	0.2	-0.5	-1.0
Body Mass Index (BMI) (2010)	0.3	0.4	1.0	0.8	0.8	-0.0	0.8	0.2	0.7	0.8	0.2	1.0	0.7	0.3	0.7	0.8	0.9	0.1	0.5	0.1	-0.0	0.5
BMI	0.3	1.9	7.5	-0.8	-0.9	0.2	-0.8	-2.7	-0.9	-0.9	-0.9	-0.7	-0.7	-0.8	-0.9	-1.5	-0.7	1.8	-0.9	-2.7	-2.2	-1.8
Neuroticism	0.3	0.7	2.8	-0.3	-0.4	1.5	-0.2	-1.5	-0.4	-0.4	-0.2	-0.4	-0.3	-0.4	-0.4	-1.1	-0.3	-0.0	-0.3	-1.7	-1.5	-1.3
Tanning	0.3	3.3	6.4	-2.1	-1.9	0.3	-2.1	-1.5	-2.0	-2.0	-2.5	-1.7	-2.0	-1.9	-2.0	-1.5	-1.6	1.6	-1.1	-1.8	-2.5	-1.2
Frequency of depressed mood in last 2 weeks	0.3	0.4	4.2	-0.0	0.0	2.1	0.0	-1.0	-0.1	0.0	-0.0	-0.0	-0.1	0.5	0.1	-0.5	0.2	-0.7	-0.3	-0.5	-0.6	0.0
Systolic blood pressure, automated reading	0.3	0.9	9.0	-0.2	-0.3	-3.0	-0.3	-0.5	-0.2	-0.2	-0.3	-1.0	-0.2	-1.2	-0.2	-0.9	-0.3	0.5	-0.3	-1.1	-1.0	-1.0
Leg fat-free mass (left)	0.3	1.6	3.2	1.5	1.4	1.6	1.5	-1.0	1.5	1.4	1.6	1.8	1.6	1.0	1.5	0.9	1.7	0.1	0.3	-1.1	-0.4	0.1
Qualifications: CSEs or equivalent	0.3	0.3	2.1	0.3	0.3	0.1	0.2	0.2	0.3	0.3	0.1	0.3	0.3	0.6	0.3	0.0	0.2	-1.4	-0.9	0.1	-0.7	-1.3
Leg predicted mass (left)	0.3	1.7	3.4	1.6	1.5	1.6	1.6	-1.0	1.5	1.4	1.7	1.9	1.6	1.0	1.6	0.9	1.7	0.1	0.3	-1.0	-0.3	0.2
Waist circumference	0.3	0.9	5.1	-0.2	-0.3	0.9	-0.2	-2.2	-0.3	-0.2	-0.4	-0.2	-0.1	-0.3	-0.3	-1.1	-0.1	0.9	-1.0	-2.2	-1.4	-1.2
Forced vital capacity (FVC)	0.3	1.0	7.1	0.3	0.4	2.7	0.3	-1.9	0.3	0.1	0.7	0.6	0.2	0.4	0.3	1.7	0.9	0.9	0.7	-0.2	-0.7	1.3
Neuroticism score	0.3	0.6	2.3	-0.2	-0.2	1.5	-0.2	-1.4	-0.2	-0.1	-0.2	-0.4	-0.2	-0.3	-0.2	-1.1	0.0	-0.6	-0.5	-1.2	-1.5	-1.1
Asthma	0.3	0.6	2.4	0.8	0.7	0.7	0.9	1.6	0.8	0.7	0.7	0.9	0.8	0.3	0.7	-0.1	0.6	-1.0	1.1	-0.1	0.5	0.2
Medication: Lansoprazole	0.3	0.3	2.1	0.1	0.0	1.5	0.3	-1.3	0.0	-0.0	0.1	0.4	0.2	0.0	0.1	0.1	0.2	-0.8	-0.3	0.6	-0.7	0.2
Arm fat mass (right)	0.3	1.3	6.0	-0.2	-0.6	1.2	-0.1	-2.5	-0.4	-0.5	-0.5	-0.2	-0.0	-0.3	-0.5	-1.4	-0.4	0.8	-1.6	-2.2	-1.7	-1.8
Peak expiratory flow (PEF)	0.3	0.7	3.6	0.2	0.2	1.4	0.2	-1.9	0.2	0.2	0.2	0.4	0.2	0.5	0.2	0.0	0.4	-0.5	-1.5	-0.9	-1.8	-0.9
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	4.8	0.4	0.3	0.6	0.5	2.2	0.3	0.3	0.0	0.2	0.4	0.8	0.4	0.1	0.3	-1.5	-0.3	0.3	0.3	0.1
Glaucoma (self-reported)	0.3	0.3	0.9	-0.6	-0.5	-0.5	-0.6	0.0	-0.6	-0.4	-0.2	-0.3	-0.7	-0.3	-0.6	-0.7	-0.6	1.0	0.9	-0.9	0.0	-0.1
Medication: Amlodipine	0.3	0.4	2.4	0.4	0.3	0.1	0.5	-0.6	0.4	0.2	0.8	0.8	0.5	0.3	0.3	1.4	0.3	0.1	0.3	1.5	0.4	0.8
Wheeze or whistling in the chest in last year	0.3	0.6	2.5	-0.1	-0.3	1.3	0.1	-0.2	-0.2	-0.4	-0.4	0.3	-0.0	-0.6	-0.3	-1.0	-0.2	-0.6	-0.6	-1.6	-1.3	-1.6
Medication for pain relief, constipation, heartburn	0.3	0.5	4.3	0.5	0.4	-0.9	0.5	2.1	0.4	0.3	0.0	0.5	0.5	-0.0	0.5	0.7	0.2	-0.8	0.1	1.1	0.9	0.4
Whole body fat-free mass	0.3	1.5	3.2	1.5	1.5	0.7	1.5	-0.8	1.5	1.4	1.6	1.8	1.5	0.6	1.5	1.1	1.7	0.2	0.6	-0.8	-0.3	0.4
Diabetes diagnosed by doctor	0.3	0.5	4.9	0.2	0.2	-2.2	0.1	0.8	0.2	0.2	-0.1	-0.5	0.3	-0.4	0.2	0.4	-0.0	0.0	0.3	0.6	1.2	0.4
Friendships satisfaction	0.3	0.3	3.4	0.2	0.2	1.3	0.2	1.8	0.2	0.1	-0.2	0.2	0.1	0.5	0.3	-0.3	0.0	-0.6	-0.2	-0.1	0.5	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.7	-0.2	0.2	-0.7	-0.3	-1.2	0.1	0.2	-0.0	-0.4	-0.3	0.3	0.1	0.5	0.1	0.6	1.3	0.8	0.5	0.9
Back pain experienced in last month	0.3	0.4	1.0	0.5	0.8	0.9	0.4	0.3	0.6	0.7	0.4	0.2	0.4	0.8	0.7	0.3	0.9	-0.8	0.9	0.7	0.4	1.0
Mineral and other dietary supplements	0.3	0.5	0.9	-0.7	-0.6	0.8	-0.7	-0.6	-0.7	-0.6	-0.6	-0.8	-0.7	-0.7	-0.6	-0.9	-0.6	0.8	-0.7	-0.7	-0.4	-0.7
Asthma (self-reported)	0.3	0.6	2.1	0.8	0.6	0.9	0.9	1.4	0.7	0.7	0.8	1.0	0.8	0.3	0.7	0.0	0.6	-1.1	0.6	0.1	0.3	0.1
Medication: Gliclazide	0.3	0.4	2.3	0.2	0.3	-0.1	0.1	-0.4	0.3	0.3	0.0	-0.2	0.1	-0.1	0.3	1.1	0.5	-0.0	0.9	1.2	0.6	1.5
Illnesses of father: None of the above (group 1)	0.3	0.3	2.4	0.1	0.5	-0.7	-0.1	1.6	0.4	0.7	0.2	0.3	-0.0	0.4	0.4	0.0	0.3	1.0	0.2	0.1	1.0	0.2
Average weekly champagne plus white wine intake	0.3	0.5	2.5	0.3	0.3	0.2	0.3	-0.6	0.3	-0.0	0.6	0.4	0.3	0.6	0.2	1.3	0.5	0.0	0.2	1.6	0.6	1.5
Guilty feelings	0.3	0.5	1.7	0.6	0.7	1.1	0.6	-1.3	0.7	0.8	0.5	0.2	0.5	0.8	0.7	0.6	1.1	-0.9	0.4	-0.3	-0.7	0.3
Hearing aid user	0.3	0.4	1.3	-0.5	-0.6	-1.2	-0.5	0.3	-0.6	-0.9	-0.5	-0.6	-0.4	-0.8	-0.5	0.2	-0.7	0.9	0.3	0.5	0.6	0.3
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.1	0.5	0.6	1.5	0.6	-0.7	0.6	0.6	0.3	0.5	0.5	0.5	0.6	0.3	0.9	-0.6	0.4	0.0	-0.2	0.8
Number of operations (self-reported)	0.3	0.5	5.3	-0.3	-0.2	0.6	-0.2	-2.3	-0.2	-0.1	-0.2	-0.2	-0.3	0.2	-0.2	-0.6	-0.1	0.4	-0.5	-0.8	-1.0	-1.0
Ever depressed for a whole week	0.3	0.3	2.1	0.4	0.5	1.5	0.3	0.3	0.5	0.5	0.5	0.1	0.2	0.6	0.5	-0.7	0.6	-0.5	1.0	-0.3	0.3	0.4
Supplements: Calcium	0.3	0.3	1.5	-0.2	-0.1	-0.2	-0.2	1.2	-0.1	-0.0	-1.0	-0.5	-0.2	-0.2	-0.1	0.2	-0.2	-1.0	-0.3	1.1	0.1	-0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.5	3.6	0.0	-0.0	-0.7	0.1	1.9	-0.0	-0.1	-0.3	-0.2	0.1	-0.0	0.0	-0.2	-0.1	-0.7	-0.1	1.4	1.3	0.8
Crohns Disease (2012)	0.2	0.4	1.1	-0.6	-0.6	-0.8	-0.6	-0.5	-0.5	-0.5	0.1	-0.8	-0.6	-0.6	-0.6	-0.3	-0.6	1.0	-1.0	0.6	-0.1	-0.3
HDL Cholesterol	0.2	0.4	1.6	-0.3	-0.3	-0.1	-0.3	-1.3	-0.3	-0.2	-0.2	-0.1	-0.3	0.2	-0.3	-0.4	-0.3	0.3	-0.8	-1.1	-1.3	-1.1
Lupus	0.2	0.3	3.1	0.1	0.2	1.8	0.1	0.4	0.3	0.6	-0.4	-0.0	0.1	0.6	0.1	-0.4	0.3	-0.4	0.1	-0.4	0.1	0.2
Triglycerides	0.2	0.3	1.9	0.1	0.1	0.5	0.1	-0.4	0.1	-0.0	0.1	0.0	0.1	-0.2	0.0	0.1	0.3	1.1	1.4	-0.5	0.3	0.9
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.6	-0.7	-0.6	-0.0	-0.6	0.5	-0.7	-0.7	-0.8	-0.7	-0.7	-0.8	-0.4	-0.4	-0.5	0.3	-0.0	0.1	-0.2	0.1
Respiratory disease	0.2	0.5	5.4	0.2	0.1	-0.0	0.3	2.3	0.2	0.3	-0.3	0.2	0.2	-0.3	0.1	-0.8	0.0	-0.9	-0.2	-0.7	-0.1	-0.8
Lung FVC	0.2	0.9	3.9	1.0	0.9	2.0	1.1	0.2	0.9	0.8	1.4	1.2	1.1	1.2	0.9	1.1	0.8	0.0	0.6	-0.1	0.4	0.2
Supplements: Zinc	0.2	0.2	1.2	0.0	0.3	0.0	-0.0	0.4	0.2	0.2	-0.4	-0.1	-0.1	0.4	0.2	-0.5	0.2	0.9	1.1	-1.0	0.1	0.3
Medication: Metformin	0.2	0.3	2.8	-0.2	-0.1	-1.7	-0.3	0.6	-0.2	-0.1	-0.5	-0.7	-0.3	-0.6	-0.1	-0.2	-0.3	0.2	0.1	0.3	0.6	0.1
Diabetes (father)	0.2	0.3	1.3	0.1	-0.1	0.8	0.2	-0.8	-0.1	-0.3	0.3	-0.0	0.1	0.1	-0.1	-0.8	0.1	-0.3	-0.6	-1.1	-1.1	-0.8
Hand grip strength (right)	0.2	0.7	3.0	0.6	0.4	-1.1	0.6	0.8	0.4	0.3	0.8	0.3	0.5	-0.5	0.5	0.6	0.3	0.2	1.7	1.0	1.4	1.3
Fed-up feelings	0.2	0.3	3.5	0.1	0.1	0.7	0.1	-1.9	0.1	0.1	0.7	-0.3	0.1	0.0	0.2	-0.4	0.4	0.0	0.4	-0.4	-0.4	0.3
Taking other prescription medications	0.2	0.4	3.6	-0.4	-0.2	0.4	-0.4	-1.9	-0.3	-0.4	-0.2	-0.2	-0.4	-0.1	-0.2	-0.2	-0.1	0.7	-0.3	-0.8	-0.9	-0.5
Age when periods started (menarche)	0.2	0.4	1.9	-0.6	-0.5	-0.3	-0.6	-0.4	-0.5	-0.7	-0.4	-0.4	-0.7	-0.5	-0.5	0.8	-0.6	0.6	0.5	1.4	0.5	1.0
High blood pressure (mother)	0.2	0.3	1.7	-0.4	-0.3	0.3	-0.5	-0.2	-0.4	-0.2	-0.3	-0.5	-0.5	-0.5	-0.4	-0.5	-0.2	-0.4	-1.3	-0.2	-1.0	-0.6
Nervous feelings	0.2	0.3	1.7	-0.4	-0.4	0.5	-0.4	-0.7	-0.4	-0.4	-0.9	-0.9	-0.4	-0.1	-0.4	-1.0	-0.3	0.1	0.2	-1.3	-0.6	-0.5
Had menopause	0.2	0.3	1.9	0.3	0.2	-0.1	0.4	-0.1	0.3	0.3	0.5	0.0	0.4	0.1	0.2	0.2	0.2	-0.2	0.3	1.4	0.9	1.2
Weight	0.2	1.0	5.2	0.1	-0.0	1.1	0.2	-2.3	0.1	-0.0	-0.0	0.2	0.3	-0.2	0.1	-0.8	0.3	1.1	-1.1	-2.3	-1.6	-1.2
Impedance of arm (right)	0.2	0.9	11.4	-0.0	-0.1	3.4	0.1	-0.6	-0.1	0.1	-0.1	-0.4	0.0	1.4	-0.1	-0.4	-0.1	-1.3	-1.2	0.2	-0.3	-0.4
Trunk fat-free mass	0.2	1.3	2.7	1.4	1.3	0.3	1.3	-0.9	1.4	1.2	1.5	1.6	1.4	0.3	1.4	1.2	1.6	0.4	0.8	-0.8	-0.3	0.6
Hip circumference	0.2	1.0	3.9	-0.1	-0.1	1.3	-0.0	-1.9	-0.1	-0.0	-0.1	0.2	0.0	-0.1	-0.1	-1.3	0.2	0.4	-1.8	-2.0	-1.8	-1.5
Number of live births	0.2	0.3	0.8	0.5	0.6	-0.4	0.5	0.2	0.6	0.7	-0.2	0.2	0.4	0.4	0.6	-0.1	0.8	-0.5	-0.5	-0.9	-0.7	-0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	1.8	-0.1	0.0	0.7	-0.1	-0.4	-0.0	0.1	-0.0	-0.0	-0.0	0.0	-0.0	-0.3	-0.0	-0.5	-1.0	-1.0	-1.1	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.6	0.1	0.3	0.4	0.1	0.0	0.2	0.3	0.2	0.2	0.1	0.8	0.2	-1.2	0.1	-0.5	-0.8	-0.9	-0.3	-1.3
Impedance of arm (left)	0.2	0.8	5.8	-0.6	-0.5	2.4	-0.5	-0.6	-0.5	-0.4	-0.6	-1.0	-0.5	0.7	-0.5	-0.6	-0.5	-1.0	-1.8	0.4	-0.6	-0.7
Trunk predicted mass	0.2	1.2	2.6	1.3	1.2	0.3	1.2	-0.8	1.3	1.2	1.4	1.6	1.3	0.2	1.3	1.1	1.6	0.4	0.7	-0.8	-0.4	0.5
Standing height	0.2	2.4	5.4	1.7	1.8	2.3	1.6	-1.0	1.8	1.6	1.9	1.6	1.6	1.3	1.8	1.9	2.3	-0.4	0.4	-0.1	-0.2	1.4
Length of working week for main job	0.2	0.2	2.2	0.1	0.1	0.3	0.2	1.5	0.1	0.1	-0.3	-0.0	0.2	0.1	0.2	-0.1	-0.1	-0.6	0.4	0.4	0.9	0.1
Tense / ‘highly strung’	0.2	0.3	2.2	0.4	0.3	1.5	0.5	-0.2	0.3	0.4	-0.0	0.2	0.5	0.4	0.4	-0.6	0.3	-1.0	0.1	-1.0	-0.5	-0.7
Loud music exposure frequency	0.2	0.2	2.0	0.3	0.3	-0.1	0.3	0.5	0.3	0.2	-0.1	-0.1	0.3	0.1	0.3	0.1	0.5	-1.4	-0.2	0.5	-0.3	0.3
Medication: Paracetamol	0.2	0.3	1.2	0.6	0.7	-0.0	0.5	-1.1	0.7	0.7	0.6	0.2	0.6	0.8	0.6	0.4	0.8	-0.1	0.4	-0.3	-0.4	0.0
Neck or shoulder pain in last month	0.2	0.3	2.6	0.2	0.3	0.4	0.1	-0.6	0.3	0.3	0.4	-0.1	0.1	-0.4	0.3	0.3	0.5	1.6	0.8	-0.5	0.3	0.7
Heart disease (mother)	0.2	0.3	0.8	-0.4	-0.4	-0.0	-0.4	-0.7	-0.4	-0.4	-0.1	-0.7	-0.4	-0.6	-0.4	-0.3	-0.4	0.8	-0.3	-0.9	-0.6	-0.5
Comparative height size at age 10	0.2	1.3	4.6	1.1	1.2	2.1	1.1	-0.9	1.2	1.2	1.6	1.2	1.1	0.7	1.2	1.1	1.5	0.6	0.5	-0.4	0.2	1.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.3	-0.6	-0.3	0.1	-0.6	1.1	-0.4	-0.3	-0.4	-0.3	-0.6	-0.2	-0.3	0.1	-0.5	0.3	0.0	0.7	0.5	-0.1
Medication: Aspirin	0.2	0.2	1.1	-0.3	-0.2	0.8	-0.3	-1.0	-0.2	-0.0	-0.3	-0.4	-0.3	-0.1	-0.3	-0.6	-0.2	0.4	-0.2	-0.7	-0.5	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	2.0	0.1	0.1	-0.2	0.2	-1.4	0.1	-0.0	0.7	0.6	0.2	-0.2	0.1	0.1	0.3	-0.3	-0.3	0.2	-0.7	0.1
Commuting to job workplace: Walk	0.2	0.2	1.0	0.3	0.0	0.8	0.4	-0.7	0.1	-0.0	0.5	0.8	0.3	0.3	0.1	0.3	0.3	-0.1	-0.2	-0.6	-1.0	-0.0
Osteoporosis (self-reported)	0.2	0.2	0.9	0.3	0.2	-1.0	0.3	0.9	0.3	0.4	-0.2	0.2	0.4	0.3	0.3	-0.4	0.1	-0.8	0.1	-0.3	0.4	-0.3
Medication: Aspirin	0.2	0.3	1.3	-0.4	-0.3	0.4	-0.4	-1.2	-0.3	-0.1	-0.6	-0.6	-0.4	-0.2	-0.4	-0.5	-0.2	0.2	-0.5	-0.5	-0.8	-0.5
Whole body water mass	0.2	1.3	3.0	1.4	1.4	0.7	1.4	-0.8	1.4	1.3	1.5	1.7	1.4	0.5	1.4	1.1	1.6	0.3	0.5	-0.9	-0.3	0.4
Basal metabolic rate	0.2	0.9	1.8	1.1	1.0	0.7	1.0	-1.3	1.0	0.9	1.1	1.3	1.1	0.2	1.1	0.5	1.3	0.6	0.2	-1.4	-0.7	-0.0
Irritability	0.2	0.3	2.1	0.2	0.1	0.4	0.2	-1.4	0.1	-0.0	0.3	0.5	0.2	0.4	0.1	0.1	0.3	-0.3	-0.5	-0.6	-1.1	-0.5
Blood Eosinophil Count	0.1	0.6	3.5	0.6	0.5	-0.1	0.6	0.3	0.6	0.7	0.2	0.1	0.6	0.1	0.6	0.3	0.7	-0.8	1.6	0.9	1.2	1.9
Blood Platelet Count	0.1	1.5	8.1	0.2	0.1	2.4	0.4	2.9	0.2	0.3	-0.3	0.8	0.3	1.0	0.1	-1.1	-0.2	-2.5	-1.8	1.0	0.5	-0.8
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	1.5	-0.1	-0.3	-1.2	-0.1	0.2	-0.3	-0.2	-0.3	-0.4	-0.1	-0.4	-0.2	0.2	-0.2	0.2	0.3	-0.1	-0.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	2.0	-0.0	-0.3	0.5	0.1	-0.2	-0.2	-0.2	-0.4	0.5	0.1	0.1	-0.2	-0.2	-0.3	0.3	0.4	-1.4	-0.5	-0.7
Sitting height	0.1	0.9	2.7	1.3	1.2	0.3	1.1	-0.8	1.2	1.1	1.1	0.7	1.2	0.5	1.3	0.2	1.6	-0.5	-0.4	-1.1	-0.6	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	2.8	-0.2	-0.5	1.7	0.0	0.5	-0.4	-0.3	-0.3	0.3	-0.0	-0.0	-0.3	-0.3	-0.6	0.4	0.6	-0.5	0.2	-0.3
Fluid intelligence score	0.1	0.2	2.3	-0.0	0.1	0.5	0.0	1.5	-0.0	-0.0	-0.4	0.3	-0.0	0.0	0.1	-0.2	0.0	-0.4	-0.1	0.6	0.8	0.5
Alcohol intake versus 10 years previously	0.1	0.2	0.9	0.1	-0.1	0.5	0.2	0.3	-0.0	-0.2	0.6	0.5	0.3	0.1	-0.1	0.0	-0.1	0.8	1.0	-0.5	0.2	0.4
Happiness	0.1	0.2	0.5	0.5	0.4	0.6	0.5	0.4	0.4	0.4	0.2	0.5	0.5	0.6	0.4	-0.2	0.1	-0.0	0.1	-0.4	0.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.8	-0.3	-0.1	0.0	-0.3	-0.1	-0.2	-0.2	-0.0	-0.3	-0.3	-0.1	-0.2	0.4	0.1	0.6	0.0	0.7	0.1	0.9
Medication: Cholesterol lowering	0.1	0.1	0.7	-0.2	-0.0	-0.5	-0.3	-0.5	-0.1	0.1	0.1	0.3	-0.3	-0.3	-0.0	-0.1	-0.2	0.8	0.7	-0.2	0.2	-0.1
Illnesses of mother	0.1	0.1	0.4	0.2	0.0	0.2	0.2	0.5	0.1	0.0	-0.3	0.4	0.3	0.3	0.1	0.5	0.1	0.1	0.3	0.2	0.6	0.6
Arm fat-free mass (right)	0.1	0.4	2.0	0.3	0.3	-1.0	0.2	-1.1	0.3	0.2	0.3	0.5	0.2	-0.8	0.3	0.3	0.6	1.4	0.1	-1.2	-0.7	0.1
Comparative body size at age 10	0.1	0.3	1.1	-0.1	0.0	0.6	-0.1	-0.4	0.0	-0.0	0.6	0.4	-0.1	0.0	-0.0	1.0	0.1	1.0	0.6	0.9	0.6	1.1
Arm predicted mass (right)	0.1	0.4	1.8	0.1	0.1	-0.8	0.0	-1.1	0.1	0.0	0.3	0.4	0.1	-0.9	0.2	0.1	0.4	1.3	-0.3	-1.2	-1.0	-0.2
Pulse rate, automated reading	0.1	0.4	1.5	0.6	0.4	-1.2	0.6	0.6	0.5	0.7	0.7	0.1	0.7	0.2	0.5	-0.8	0.1	-0.8	0.4	-1.0	0.2	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	1.3	-0.3	-0.2	1.1	-0.2	-0.6	-0.3	-0.2	-0.2	0.1	-0.3	-0.3	-0.2	0.1	0.1	-0.4	0.0	0.1	-0.3	0.4
Knee pain experienced in last month	0.1	0.2	1.1	0.2	0.3	0.1	0.1	-0.7	0.3	0.5	0.5	-0.3	0.1	0.5	0.3	-1.1	0.4	0.1	0.7	-0.6	0.0	0.3
Long-standing illness, disability or infirmity	0.1	0.1	1.2	0.3	0.3	0.2	0.3	-1.1	0.3	0.2	0.2	0.3	0.3	0.4	0.3	0.2	0.2	0.2	0.2	-0.2	-0.2	-0.3
Wears glasses or contact lenses	0.1	0.1	0.5	0.1	-0.2	0.0	0.2	0.3	-0.1	-0.3	-0.1	0.2	0.3	-0.4	-0.1	0.4	-0.3	0.7	0.7	0.0	0.6	0.4
Commuting to job workplace: Public transport	0.1	0.1	0.3	0.3	0.0	-0.5	0.3	-0.4	0.1	-0.0	0.4	0.5	0.4	0.3	0.1	0.2	-0.1	-0.2	0.6	-0.1	0.1	-0.2
High cholesterol (Self-reported)	0.1	0.3	0.8	-0.5	-0.4	0.6	-0.5	-0.9	-0.4	-0.4	-0.5	-0.6	-0.5	-0.6	-0.4	-0.1	-0.6	0.8	0.5	0.1	0.3	-0.2
Medication: Paracetamol	0.1	0.2	1.8	-0.3	-0.2	-0.0	-0.4	-1.4	-0.2	-0.2	-0.2	-0.3	-0.2	0.1	-0.3	0.2	0.1	0.6	-0.2	-0.7	-1.0	-0.3
Arm fat-free mass (left)	0.1	0.7	2.1	0.8	0.7	0.3	0.7	-1.3	0.8	0.7	1.0	1.1	0.7	-0.1	0.8	0.4	1.0	0.9	0.1	-1.5	-0.7	-0.1
Risk taking	0.1	0.1	0.7	-0.2	-0.1	0.8	-0.2	-0.6	-0.2	-0.3	-0.1	-0.1	-0.3	0.2	-0.2	0.1	-0.0	0.2	-0.1	0.1	0.2	0.6
Arm predicted mass (left)	0.1	0.6	1.8	0.9	0.9	-0.1	0.8	-0.9	0.9	0.8	1.0	1.1	0.9	-0.0	0.9	0.3	1.1	0.8	0.4	-1.4	-0.5	0.0
Hair Pigment	0.0	1.4	3.5	-1.4	-1.3	-0.6	-1.4	-0.1	-1.4	-1.4	-1.9	-0.8	-1.5	-1.3	-1.4	-0.8	-1.1	1.4	-0.3	-1.4	-0.8	-0.5
Loneliness, isolation	0.0	0.0	0.2	0.2	0.1	0.1	0.3	-0.0	0.2	0.1	0.0	-0.3	0.3	0.2	0.2	-0.1	0.0	0.2	0.4	0.0	0.1	-0.3

Hub : Genes

CHCHD5

Models

Trait associations