Hub : Genes

STEAP3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0750	0.0230	4.7e-05	0.050	0.039	0.046	0.040	0.058	8.9e-07	1.3e-05	2.2e-06	1.1e-05	1.5e-07
2	GTEx	Adipose Subcutaneous	0.1390	0.0420	1.1e-04	0.098	NA	0.068	NA	0.083	2.2e-08	NA	2.9e-06	NA	2.4e-07
3	GTEx	Adipose Visceral Omentum	0.1720	0.0550	6.3e-04	0.128	NA	0.083	NA	0.124	3.9e-07	NA	4.2e-05	NA	5.7e-07
4	GTEx	Adrenal Gland	0.1724	0.0700	9.0e-03	0.002	NA	-0.008	NA	0.010	2.7e-01	NA	9.3e-01	NA	1.3e-01
5	GTEx	Artery Aorta	0.1560	0.0610	3.0e-03	0.038	NA	0.012	NA	0.035	3.5e-03	NA	6.9e-02	NA	5.2e-03
6	GTEx	Brain Cerebellum	0.4410	0.0980	4.0e-05	0.325	NA	0.278	NA	0.337	2.4e-10	NA	7.6e-09	NA	9.3e-11
7	GTEx	Cells Transformed fibroblasts	0.1540	0.0470	2.9e-04	0.022	NA	0.026	NA	0.036	8.6e-03	NA	4.2e-03	NA	9.7e-04
8	GTEx	Colon Transverse	0.3300	0.0720	8.6e-08	0.298	NA	0.260	NA	0.290	1.1e-14	NA	1.0e-12	NA	3.0e-14
9	GTEx	Esophagus Mucosa	0.1970	0.0450	4.1e-07	0.147	NA	0.134	NA	0.141	4.8e-10	NA	3.0e-09	NA	1.1e-09
10	GTEx	Lung	0.1344	0.0422	2.2e-04	0.000	NA	0.012	NA	-0.001	3.1e-01	NA	3.9e-02	NA	3.8e-01
11	GTEx	Skin Not Sun Exposed Suprapubic	0.2780	0.0630	1.4e-06	0.203	NA	0.203	NA	0.195	2.4e-11	NA	2.2e-11	NA	5.9e-11
12	GTEx	Skin Sun Exposed Lower leg	0.2010	0.0450	1.9e-07	0.146	NA	0.164	NA	0.158	4.2e-12	NA	1.7e-13	NA	5.0e-13
13	GTEx	Whole Blood	0.1120	0.0330	5.6e-05	0.054	NA	0.054	NA	0.062	1.1e-05	NA	1.0e-05	NA	2.4e-06
14	METSIM	Adipose	0.2358	0.0438	0.0e+00	0.131	0.152	0.179	0.179	0.162	4.3e-19	4.1e-22	4.4e-26	4.4e-26	1.7e-23
15	ROSMAP	Brain Pre-frontal Cortex	0.0888	0.0291	1.4e-04	0.035	0.026	0.031	0.025	0.021	2.1e-05	2.4e-04	6.0e-05	3.3e-04	9.1e-04
16	TCGA	Colon Adenocarcinoma	0.0710	0.0380	3.8e-03	0.051	0.031	0.044	NA	0.031	6.5e-04	6.2e-03	1.4e-03	NA	6.5e-03
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.0507	0.0205	1.0e-04	0.038	0.032	0.023	NA	0.037	3.7e-05	1.4e-04	1.1e-03	NA	4.4e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	1.0	1.5	4.4	1.5	0.4	0.7	0.2	2.1	-0.9	0.2	1.9	-1.4	0.1	-0.6	-0.7	1.8	1.4	2.0	1.2	0.7
Bipolar Disorder or Schizophrenia	1.0	2.3	5.4	1.9	1.6	1.7	0.3	2.0	-0.6	-0.3	2.3	-1.3	0.4	-0.4	-1.0	1.8	2.1	2.1	1.2	2.0
Depressed Affect (Nagel 2018)	1.9	4.0	10.2	-2.1	2.1	2.2	-1.2	-2.3	-2.0	-0.9	-2.4	2.3	1.3	1.8	2.3	-1.3	2.4	-3.2	-1.5	1.3
Depression (Nagel 2018)	1.6	2.4	6.6	-1.3	2.3	2.5	-1.0	-1.4	-0.9	0.5	-2.0	1.4	1.0	1.1	1.3	-0.7	2.6	-1.8	-0.7	1.7
Intelligence (Savage-Jansen 2018)	1.3	4.1	11.6	-3.0	-0.5	-0.6	-1.3	-2.1	-2.0	0.7	-3.4	2.3	-3.1	1.9	2.3	-2.2	-0.7	-1.7	-2.4	-0.8
Neuroticism (Nagel 2018)	1.8	4.3	10.0	-2.8	1.0	1.2	-1.2	-2.7	-1.7	-0.0	-2.7	3.2	0.5	2.5	3.1	-1.7	1.8	-2.9	-1.5	0.5
Schizophrenia (2018)	0.6	1.2	4.0	1.1	1.7	1.7	0.2	0.8	-0.1	-0.6	1.5	-0.6	0.4	-0.0	-0.7	0.8	1.6	1.0	0.7	2.0
Schizophrenia vs Biploar Disorder	0.4	0.5	2.2	0.9	0.1	-0.3	-0.1	0.8	0.1	-0.7	1.1	-0.5	1.5	-1.3	-1.1	0.5	0.4	0.1	0.5	0.1
Worry (Nagel 2018)	0.6	1.3	3.6	-1.5	0.2	0.4	-0.5	-1.9	0.4	-0.1	-1.8	1.7	0.5	0.8	1.5	-1.5	0.4	-1.6	-1.1	0.1
Alzheimer’s Disease (in mother)	1.8	2.1	5.1	-1.5	-0.2	-0.4	-2.3	-2.0	-1.6	-0.6	-1.8	2.0	-1.9	0.6	1.0	-1.9	-0.9	-1.1	-1.7	-1.0
Alzheimer’s Disease (in father)	1.6	1.7	4.4	-1.6	0.6	0.7	-2.1	-2.1	-1.1	-1.0	-1.8	0.8	0.2	0.5	0.7	-1.7	-0.5	-2.0	-1.6	0.3
Alzheimer’s Disease (including proxy)	2.5	3.6	8.3	-2.1	0.8	0.8	-2.9	-2.6	-2.1	-0.8	-2.5	2.7	-0.6	1.6	2.1	-2.3	0.2	-2.0	-2.3	-0.2
Crohns Disease (2017)	1.2	2.6	7.5	2.1	0.7	0.1	2.1	2.6	-1.6	1.3	2.2	-1.4	0.4	-0.1	-0.2	2.4	1.0	2.7	1.6	0.7
Irritable Bowel Disease (IBD)	0.4	1.0	2.8	1.5	1.6	1.1	1.1	0.8	-1.7	-1.4	1.1	-0.6	-0.2	0.1	-0.1	0.6	1.1	1.0	-0.3	0.9
Ulcerative Colitis (UC)	0.9	1.6	10.2	0.2	1.6	1.4	-0.1	-0.7	-1.4	-3.2	-0.4	0.8	-1.0	0.7	0.6	-1.1	0.8	-1.1	-2.0	0.7
Major Depression (MDD)	0.4	0.5	1.2	-0.4	0.7	0.8	0.1	0.1	-0.7	-0.7	1.1	0.2	-1.1	0.5	0.6	0.7	0.9	0.1	0.9	1.0
Reaction Time	1.0	1.9	4.5	-1.5	1.0	1.2	-2.0	-2.1	0.1	-1.1	-2.0	1.1	-0.9	0.2	0.5	-2.1	0.3	-1.5	-2.1	0.6
Verbal and Numeric Reasoning (VNR)	0.9	2.2	6.5	-1.9	0.3	0.1	-0.8	-1.9	-1.3	-0.7	-2.1	1.7	-2.5	1.1	1.7	-1.8	-0.4	-0.9	-2.2	-0.3
Breast Cancer	0.9	2.2	5.1	-1.8	-2.0	-2.3	0.1	-1.1	-1.0	0.6	-1.3	1.7	-1.2	1.9	1.5	-0.9	-1.8	-1.3	-0.4	-2.0
Ovarian Cancer	0.4	0.5	1.3	0.2	-0.6	-1.1	-0.2	0.2	-0.8	0.2	0.6	-0.5	-1.0	-0.8	-0.7	-0.1	-1.0	1.0	0.3	-1.2
Prostate Cancer	1.0	1.4	4.3	1.1	1.0	0.6	0.3	1.4	-1.2	1.3	1.5	-0.7	1.3	-0.5	-0.3	1.2	2.1	1.2	1.8	0.7
Age at First Birth	1.2	1.7	5.1	-1.8	-0.4	-0.9	-1.1	-1.6	-1.2	-0.7	-1.4	1.7	-2.3	0.6	0.9	-1.6	-0.4	-2.3	-0.4	-0.8
Bipolar Disorder (2011)	1.8	1.8	3.7	1.9	1.7	1.6	0.7	1.2	1.2	-1.0	1.5	-1.4	0.3	-0.7	-0.7	1.4	1.4	1.9	0.5	1.9
Body Mass Index (BMI) (2010)	0.5	0.7	2.8	0.8	1.1	1.0	-0.4	0.4	0.2	0.6	0.6	-0.4	1.7	-0.3	-0.1	0.7	1.4	-0.2	0.6	1.3
Coronary Artery Disease (CAD)	0.4	0.5	1.7	1.1	0.4	-0.1	-0.5	0.6	-0.8	-0.1	0.4	-0.9	0.2	-1.3	-1.1	0.6	0.2	0.8	0.8	0.1
Crohns Disease (2012)	1.0	1.5	4.5	0.5	-1.0	-1.5	0.8	1.8	-1.4	1.7	1.2	-0.5	-0.3	0.2	0.3	1.5	-0.4	2.1	1.9	-1.1
Mean Putamen Volume	0.5	0.6	3.2	-0.6	0.4	0.2	-0.4	-0.4	-0.3	-1.4	-1.1	0.8	-0.9	-0.0	0.2	-0.8	-0.6	-0.3	-1.8	-0.2
Fasting Glucose	0.6	0.7	3.8	0.8	-0.4	-0.3	-0.8	-0.2	1.9	-0.3	-0.5	-1.0	-0.5	-1.6	-1.2	-0.3	-0.3	-0.3	0.0	-0.0
HbA1C	1.0	1.1	2.8	-1.1	-0.2	-0.2	-1.0	-1.5	-1.7	-1.0	-0.4	1.2	-0.1	0.4	1.0	-1.6	-0.6	-1.6	-1.5	-0.6
HDL Cholesterol	0.2	0.4	1.9	0.1	0.1	0.3	-0.4	0.2	-1.0	0.0	-0.2	0.9	0.7	1.4	0.7	0.3	1.1	-0.1	-0.5	0.4
LDL Cholesterol	0.3	0.5	2.1	-0.9	-1.0	-1.1	0.3	-0.2	-0.5	-0.6	-0.4	0.5	-0.3	0.4	0.5	-0.5	-1.4	0.1	-0.1	-1.2
Lupus	1.2	1.9	4.0	1.2	-1.5	-1.4	1.3	1.2	1.8	1.6	1.8	-1.5	0.0	-1.6	-1.2	1.6	-0.7	0.4	2.0	-0.7
Neuroticism (2016)	0.4	0.6	2.3	-0.6	0.4	0.8	0.5	-1.2	0.7	0.2	-0.9	0.7	0.4	0.4	0.8	0.1	1.4	-1.5	-0.7	0.4
Primary Biliary Cirrhosis	0.7	0.9	2.4	0.7	-1.2	-1.5	1.5	1.4	-0.1	1.5	0.6	-0.6	0.3	-0.6	-0.6	1.0	-0.5	0.2	1.1	-1.3
Rheumatoid Arthritis	0.9	1.2	4.1	0.7	0.2	0.3	1.2	2.0	2.0	1.2	0.7	-1.2	0.6	-0.9	-0.9	1.4	-1.0	0.3	0.9	0.7
Schizophrenia (2014)	0.6	1.3	3.2	1.8	1.2	1.2	-0.3	1.1	-0.2	-0.9	1.8	-0.8	0.5	-0.9	-1.5	0.8	1.6	1.1	0.9	1.4
Triglycerides	0.0	0.1	0.2	-0.2	-0.4	-0.4	-0.4	-0.1	0.3	-0.1	0.0	0.2	0.4	-0.1	0.5	0.2	0.0	-0.1	0.5	-0.1
Type 2 Diabetes (T2D) (2012)	0.9	1.1	2.9	0.9	-1.5	-0.9	1.7	0.9	0.6	0.8	1.4	-0.4	-0.9	-0.6	-0.5	1.3	-0.1	1.5	1.4	-0.7
Ulcerative Colitis	1.1	1.6	3.9	-0.6	0.8	0.8	-1.2	-1.9	-1.3	-1.8	-1.2	1.0	-1.8	0.4	0.6	-1.9	0.4	-2.0	-1.4	0.0
Blood Eosinophil Count	0.3	2.4	3.9	1.7	-1.4	-1.9	2.0	1.9	0.9	1.1	1.9	-1.6	1.4	-0.9	-1.5	1.1	-1.3	1.8	1.5	-1.6
Blood Platelet Count	0.6	6.9	21.4	3.6	0.3	0.3	1.2	2.4	2.1	1.6	3.1	-4.3	-0.2	-4.6	-3.9	2.1	0.3	3.6	2.7	0.7
Blood Red Count	0.1	1.1	2.7	0.6	-1.3	-1.6	0.4	-0.1	1.1	0.4	0.8	-0.8	0.9	-0.9	-1.1	-0.2	-1.4	-1.3	1.6	-1.3
Blood White Count	0.3	2.0	7.3	0.4	-2.2	-2.2	-0.3	-0.5	0.7	-0.1	0.4	-1.0	0.4	-1.3	-1.9	-0.9	-2.5	0.7	1.1	-2.7
Heel T-Score	0.8	6.6	34.8	-2.9	-1.4	-0.6	-2.0	-3.3	-1.3	0.9	-3.0	2.6	-5.9	1.5	1.7	-3.5	0.0	-2.9	-2.3	-1.6
BMI	0.1	0.5	2.0	0.6	0.4	-0.2	-1.4	0.3	-0.7	0.3	0.3	-0.5	0.8	-0.7	-1.0	0.1	1.0	1.1	1.1	0.2
Height	0.1	1.9	6.6	1.9	0.2	0.3	0.2	0.9	2.6	1.1	1.1	-2.1	-0.7	-2.5	-2.2	0.6	-0.5	1.2	0.8	0.2
Waist Hip Ratio (WHR)	0.1	0.2	0.8	0.4	0.5	0.1	-0.5	-0.9	0.3	-0.2	-0.4	0.4	-0.8	-0.3	-0.1	-0.5	0.6	0.5	-0.8	0.3
Systolic Blood Pressure	1.4	7.0	11.6	2.7	-2.1	-2.4	2.6	3.4	2.2	1.7	3.4	-3.3	0.4	-3.3	-3.1	2.3	-1.7	3.3	3.0	-1.9
Smoking Status	0.1	0.3	1.0	-0.0	0.5	0.6	0.7	0.5	-0.2	-1.0	0.0	-0.0	0.9	0.6	0.2	0.2	0.6	0.8	-0.0	0.9
Allergy or Eczema	1.0	2.7	6.4	-2.1	-0.5	-0.2	-2.4	-2.4	-1.8	-1.6	-1.9	1.9	-0.8	1.1	0.7	-2.5	-1.1	-2.3	-1.2	-1.0
Cardiovascular Disease	0.3	1.2	3.1	0.0	-1.7	-1.8	0.5	0.4	0.7	1.5	0.6	-0.5	-0.1	-0.4	-0.2	0.3	-1.8	1.8	1.0	-1.5
Hypothyroidism (self reported)	0.4	0.9	3.6	-0.6	0.8	0.4	-0.8	-1.5	0.5	-1.6	-0.9	0.9	-0.0	0.4	0.1	-0.8	0.6	-1.2	-1.9	0.1
Respiratory disease	0.3	0.7	3.7	0.6	-0.4	-0.9	1.2	0.6	1.1	0.0	0.1	-0.8	1.9	-0.6	-0.7	1.2	-0.4	0.6	0.8	-0.4
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.4	-0.2	-0.3	-0.6	0.3	-0.0	-0.5	-0.0	-0.3	0.5	-1.2	0.0	0.5	-0.1	0.1	-0.3	-0.0	-0.4
Lung FEV1/FVC ratio	0.9	4.6	13.0	-2.5	-2.4	-1.9	-3.6	-2.3	-1.4	-1.0	-2.4	1.8	-3.5	-0.1	0.3	-2.9	-1.3	-1.4	-1.9	-2.4
Lung FVC	0.3	1.4	5.3	0.6	2.3	2.1	1.0	0.6	0.1	-0.1	0.2	-0.1	1.2	0.7	0.4	0.4	2.1	-0.4	-0.1	2.3
Neuroticism	2.0	4.7	10.6	-2.7	1.2	1.6	-1.2	-3.1	-1.2	-0.6	-2.9	3.1	0.5	2.6	3.1	-2.0	1.6	-3.2	-2.0	0.8
Chronotype (morning person)	1.0	2.2	11.0	0.2	3.3	2.9	-1.3	-0.4	-0.1	-0.9	-0.1	0.3	-1.2	0.7	0.6	-0.3	2.1	-0.0	-0.4	3.0
Hair Pigment	0.1	3.6	8.9	-1.8	2.0	1.4	-3.0	-2.2	-1.9	-0.2	-2.2	1.9	-0.7	1.7	1.3	-2.4	2.3	-1.8	-2.6	0.8
Tanning	0.1	0.8	3.4	0.6	0.8	1.1	-0.5	-1.0	-0.1	-1.2	-0.0	-0.0	-1.8	-0.2	-0.2	-1.1	0.6	-1.6	-0.5	1.1
Hand grip strength (left)	0.7	1.8	4.0	-1.2	-0.5	-0.2	-2.0	-1.8	-1.4	-1.3	-1.3	1.7	-0.8	1.2	1.2	-1.9	-0.5	-1.5	-1.8	-0.4
Number of treatments/medications taken	0.2	0.4	1.3	-0.5	0.8	0.2	-1.1	-0.2	-0.6	-0.5	-0.8	0.5	-0.2	0.6	0.4	-0.6	1.2	0.5	-0.4	0.5
Average weekly spirits intake	3.8	4.7	9.2	2.9	0.1	-0.3	2.1	2.4	3.0	1.5	2.5	-2.9	0.9	-2.8	-2.5	2.4	0.2	2.9	2.4	0.7
Sensitivity / hurt feelings	0.3	0.6	2.0	-0.8	-0.1	-0.0	-0.1	-0.3	0.1	1.3	-0.6	0.9	-0.1	1.2	1.3	0.6	1.4	-0.1	0.8	0.5
Frequency of depressed mood in last 2 weeks	1.2	1.6	4.1	-1.2	1.6	1.7	-0.9	-1.1	-0.9	0.2	-1.7	1.4	0.3	1.5	1.6	-0.2	2.0	-1.2	-0.3	1.5
Hearing difficulty/problems: Yes	0.1	0.2	1.3	0.3	-0.2	-0.3	0.3	0.5	-0.6	1.1	0.2	-0.2	0.5	0.2	0.3	0.5	-0.1	-0.1	0.2	-0.4
Relative age of first facial hair	0.4	0.7	2.5	-1.1	-0.3	-0.3	-1.1	-1.0	-0.3	0.6	-1.3	0.9	0.1	0.4	0.5	-0.9	-0.8	-1.1	-1.6	-0.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	4.1	0.9	1.9	1.8	0.2	-0.2	1.0	0.3	-0.5	-1.4	0.1	-0.5	-0.9	0.2	2.0	-0.5	0.2	1.8
Ever used hormone-replacement therapy (HRT)	1.5	2.0	4.8	-1.9	0.2	0.2	-1.1	-1.6	-1.4	-1.0	-1.8	2.2	0.8	2.0	1.9	-1.5	0.4	-1.5	-1.4	-0.2
Ever had hysterectomy (womb removed)	0.9	1.0	3.1	-1.2	0.1	0.1	-0.3	-0.1	-1.8	-0.6	-1.1	1.6	0.2	1.5	1.7	-0.5	-0.3	-1.1	-1.4	-0.6
Systolic blood pressure, automated reading	0.5	1.4	3.0	1.7	-0.1	-0.4	1.3	1.3	0.8	0.5	1.6	-1.6	-0.6	-1.6	-1.6	0.8	0.1	1.7	1.5	-0.2
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.1	-0.6	1.1	0.9	-2.0	-1.3	-0.9	-1.3	-0.6	0.6	-1.5	-0.3	-0.1	-1.4	1.1	-0.5	-0.7	0.6
Angina	0.5	0.7	2.0	0.5	1.4	1.0	1.1	0.7	0.3	0.0	0.4	-0.5	-0.4	0.7	0.2	0.9	1.4	1.2	-0.2	1.2
Medication for hormone replacement therapy	3.4	3.8	10.1	-2.8	0.3	0.7	-1.6	-3.2	-0.9	-0.8	-3.2	2.2	0.2	2.2	2.3	-2.3	0.2	-2.5	-2.2	0.2
Vitamin and mineral supplements	0.7	0.9	4.6	0.9	-0.2	-0.2	1.5	2.1	-0.5	1.2	1.1	-0.6	1.4	0.5	-0.0	1.0	-0.1	0.6	1.3	0.1
Supplements: Zinc	0.5	0.6	2.8	-0.0	-0.4	-0.7	-1.7	-0.4	-0.4	-1.5	0.1	-0.2	-0.6	-0.5	-0.8	-0.9	-0.9	0.1	-0.3	-0.9
Medication: Co-codamol	0.9	1.0	4.4	1.3	0.1	-0.2	0.5	1.4	0.3	-0.4	2.1	-1.2	0.6	-1.0	-1.1	1.2	0.3	0.6	1.6	0.3
Medication: Metformin	0.2	0.3	1.2	0.1	0.8	0.7	-0.6	-0.1	-0.8	-0.0	-0.3	0.3	-0.8	0.3	0.4	0.2	1.1	0.4	-0.0	1.0
Diabetes (father)	0.2	0.2	2.2	-0.1	0.3	0.2	0.4	-0.4	-0.1	0.3	-0.0	0.1	-1.5	0.0	0.1	-0.2	-0.4	-0.9	-0.1	-0.3
Diabetes (mother)	0.4	0.5	1.6	-0.6	-0.2	-0.4	-0.8	-0.3	-1.2	0.0	-0.9	1.2	-0.3	1.0	1.0	-0.5	-0.3	-0.3	-1.3	-0.5
Severe depression (siblings)	1.3	1.5	3.3	1.3	0.9	0.7	-0.1	1.0	1.1	0.7	1.5	-1.7	1.4	-0.6	-1.3	1.3	1.6	1.8	0.9	1.3
Pack years adult smoking proportion	0.7	1.1	3.6	1.9	0.8	0.6	-0.6	-0.1	1.0	-0.3	1.2	-1.4	1.5	-1.5	-1.9	0.1	0.7	0.6	0.5	0.4
Impedance of leg (right)	0.3	1.3	4.9	0.8	-0.8	-0.8	1.4	2.2	0.8	1.5	1.4	-0.9	1.3	0.0	0.1	2.0	-0.6	1.0	1.0	-0.1
Leg fat-free mass (left)	0.1	0.5	2.6	0.0	0.5	0.3	-1.6	-1.1	-1.0	-0.4	-0.8	0.2	-0.3	-0.4	-0.6	-1.2	0.3	-0.3	-0.3	0.0
Trunk fat percentage	0.6	2.4	7.6	1.8	0.0	-0.2	0.8	1.6	0.9	1.3	1.7	-2.1	2.5	-1.3	-1.6	1.8	0.9	1.6	2.8	0.4
Hand grip strength (right)	0.7	1.9	6.2	-0.7	0.1	0.2	-2.5	-1.5	-1.5	-1.8	-1.3	1.4	-0.8	0.1	0.3	-2.3	-0.5	-1.5	-2.2	-0.4
Townsend deprivation index at recruitment	1.7	2.3	10.0	-0.0	3.2	3.1	0.0	-0.5	-0.4	-2.1	-0.8	0.3	0.4	1.4	0.5	-0.5	1.7	0.4	-1.3	2.6
Current tobacco smoking	0.4	0.6	1.9	0.9	0.7	0.6	0.5	1.0	1.0	-1.4	0.9	-1.0	0.5	-0.3	-1.0	0.2	0.2	1.3	0.3	0.4
Average weekly fortified wine intake	1.4	1.7	4.9	-1.4	0.2	0.4	-0.2	-1.7	-1.5	0.6	-1.4	1.9	-1.0	1.7	2.2	-0.8	0.8	-2.2	-0.4	0.3
Maternal smoking around birth	0.2	0.3	0.9	0.3	0.2	-0.0	0.9	-0.2	0.5	-0.9	0.1	-0.5	-0.5	-0.9	-0.9	-0.4	-0.5	0.1	-0.5	-0.1
Fed-up feelings	0.4	0.7	2.5	-0.4	0.9	0.6	-0.4	-0.8	-1.6	-0.3	-0.7	0.8	1.4	0.9	0.8	-0.4	1.0	-1.4	-0.3	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.2	0.0	1.7	1.8	-0.2	-0.5	0.0	-1.3	-0.7	0.4	1.0	0.2	0.1	-0.7	1.1	-0.9	-1.1	1.4
Relative age voice broke	0.7	1.1	3.0	-1.2	-0.4	-0.6	-1.7	-1.1	-1.5	-0.1	-1.0	1.3	-0.7	0.4	0.7	-1.3	-1.0	-1.0	-1.4	-0.9
Taking other prescription medications	0.7	1.1	7.1	0.7	1.6	1.1	0.2	0.9	-0.5	0.6	0.4	-0.3	0.3	-0.1	0.1	1.3	2.7	0.6	0.7	1.8
Age when periods started (menarche)	0.4	1.0	3.3	-0.6	0.4	0.7	-1.4	-1.5	-0.1	-1.3	-1.3	0.7	-1.6	-0.3	0.2	-1.8	0.1	-0.6	-1.3	0.3
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	3.6	0.2	1.9	1.9	0.6	0.8	-1.8	-0.5	-0.1	0.3	-0.1	1.4	0.7	0.1	1.4	0.1	-0.8	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	2.0	0.3	0.4	0.5	-1.1	-0.4	-0.3	0.6	0.3	0.2	-1.0	-0.4	-0.4	-0.5	1.4	0.0	-0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.9	-0.3	0.1	-0.1	-2.0	-0.9	-1.7	-0.9	-0.8	1.2	-0.8	0.7	0.4	-0.8	1.0	0.3	-0.6	-0.1
Qualifications: CSEs or equivalent	0.5	0.7	4.3	0.8	-0.1	-0.1	-0.0	1.0	0.2	2.1	0.8	-0.9	0.2	-0.4	-0.3	1.1	-0.3	1.3	1.0	0.1
Serious illness, injury or assault to yourself	1.2	1.4	4.5	-2.0	0.1	0.1	-0.4	-0.7	-1.4	0.2	-1.7	1.4	-2.1	1.6	1.7	-1.2	0.1	-1.0	-0.0	-0.4
High blood pressure	0.1	0.4	2.0	-0.0	-0.7	-0.6	0.8	0.2	0.3	0.8	0.5	-0.1	0.5	0.3	0.5	0.9	-0.2	0.5	1.4	-0.2
Hayfever, allergic rhinitis or eczema	0.7	1.6	5.5	-1.3	-0.7	-0.6	-2.3	-1.7	-1.5	-0.8	-1.3	1.1	-0.7	0.4	0.2	-2.0	-1.4	-1.6	-0.5	-1.0
Multivitamins +/- minerals	0.8	1.0	3.3	-0.7	0.9	0.8	-1.5	-1.8	-0.4	-1.5	-0.7	1.1	-0.6	0.4	0.7	-0.8	1.3	-0.3	-1.5	0.7
Stomach or abdominal pain in last month	0.4	0.5	3.2	-0.7	0.2	1.1	-0.5	-0.2	0.7	-1.8	-0.5	0.7	0.4	0.8	0.8	-0.5	0.4	-0.5	-0.5	0.3
Supplements: Glucosamine	0.3	0.4	2.2	-0.0	-1.2	-1.5	0.3	-0.0	1.0	0.7	0.5	0.3	0.7	0.0	0.2	0.0	-0.3	-0.1	0.4	-0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.7	-0.3	0.8	1.3	-1.1	-1.1	0.4	0.2	-0.8	-0.1	-0.6	-0.4	-0.1	-0.8	1.1	-0.2	-1.1	0.7
Medication: Atenolol	1.8	2.2	5.1	0.6	-1.8	-2.1	1.3	1.2	1.6	1.1	0.5	-1.8	-0.9	-1.9	-1.8	0.8	-2.3	1.5	0.8	-1.5
Medication: Levothyroxine sodium	0.1	0.1	0.5	0.1	0.1	-0.2	0.1	0.3	0.6	0.2	-0.1	-0.0	0.6	0.0	-0.1	0.5	0.7	-0.1	-0.6	0.1
Sitting height	0.1	0.4	1.8	-0.5	-1.0	-0.7	-0.2	0.1	0.5	1.4	-0.5	0.2	-0.4	-0.2	0.2	0.1	-0.6	-0.8	-0.7	-0.8
Chronic bronchitis/emphysema (father)	0.3	0.3	0.9	-0.4	1.0	0.7	-0.5	-0.4	-0.6	0.2	-0.9	-0.2	-0.4	0.3	0.0	-0.4	0.7	-0.0	-0.9	0.8
High blood pressure (mother)	0.7	0.9	4.2	-0.2	-2.1	-1.9	0.1	0.6	-0.6	1.2	-0.0	0.3	0.3	-0.4	0.1	0.9	-1.0	0.5	0.5	-1.7
Body mass index (BMI)	0.2	0.7	2.7	0.6	0.6	0.2	-1.6	-0.4	-1.0	-0.6	-0.1	-0.4	1.6	-0.9	-1.0	-0.4	1.1	0.1	0.7	0.3
Impedance of leg (left)	0.5	2.7	7.6	1.2	-1.3	-1.3	1.9	2.8	1.6	2.1	2.0	-1.7	1.3	-0.7	-0.6	2.7	-1.0	1.3	1.6	-0.5
Leg predicted mass (left)	0.1	0.6	3.0	-0.0	0.6	0.5	-1.7	-1.2	-1.1	-0.5	-0.8	0.2	-0.3	-0.3	-0.5	-1.3	0.3	-0.3	-0.4	0.1
Trunk fat mass	0.3	1.2	4.5	1.3	-0.0	-0.3	0.1	0.9	0.4	1.1	1.0	-1.5	1.6	-1.1	-1.3	1.1	0.7	1.0	2.1	0.1
Waist circumference	0.2	0.6	2.3	1.0	0.3	-0.0	-1.2	-0.5	0.3	-0.3	0.1	-0.8	0.8	-1.5	-1.5	-0.5	0.5	0.3	0.5	0.0
Number of incorrect matches in round	0.5	0.9	4.4	0.3	1.1	1.1	1.5	0.2	2.1	-1.5	0.1	-0.1	-0.4	0.4	0.2	0.2	0.4	-0.0	-1.5	0.8
Past tobacco smoking	0.4	0.7	2.2	0.7	1.4	1.5	-0.9	-0.2	-0.2	-1.1	0.3	0.1	0.8	0.3	0.2	-0.4	0.2	-1.0	-0.8	1.4
Alcohol usually taken with meals	0.2	0.2	0.8	0.0	-0.4	-0.3	0.9	0.3	0.2	0.2	0.3	0.6	0.1	0.9	0.8	0.5	-0.0	-0.9	0.1	-0.1
Nervous feelings	0.3	0.5	1.7	-1.3	-0.6	-0.4	-0.2	-0.8	0.8	0.3	-1.3	0.8	-0.4	0.7	0.9	-0.9	-0.1	-0.7	-0.7	-0.6
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	9.1	-1.7	1.4	1.2	-1.8	-2.0	-1.6	-1.8	-2.4	2.2	0.2	1.2	1.5	-1.8	1.2	-3.0	-2.2	0.7
Hearing difficulty/problems with background noise	0.6	1.0	3.3	-0.4	1.0	0.7	1.2	-0.1	-0.5	-0.3	0.0	1.0	0.7	1.8	1.7	0.3	1.3	-1.8	0.3	0.4
Hair/balding pattern: Pattern 2	0.3	0.4	1.9	0.4	-0.5	-0.9	-1.0	0.5	-1.2	-0.1	0.7	-0.1	-0.2	-0.1	-0.5	0.0	-0.0	1.4	0.6	-0.5
Had menopause	0.3	0.3	1.5	-0.5	0.0	-0.3	0.0	-0.2	-0.0	0.5	-0.6	0.7	1.2	0.5	0.5	-0.5	0.5	-0.8	-0.9	-0.3
Had other major operations	0.5	0.6	2.5	-0.6	-1.1	-1.0	-0.0	-0.6	-0.9	-0.3	-0.3	0.5	1.6	0.7	0.4	-0.4	-0.6	-0.8	0.1	-1.3
Forced vital capacity (FVC)	0.1	0.3	1.7	-0.6	0.3	0.2	-0.4	-0.1	-0.9	1.3	-0.8	0.1	0.5	0.4	0.5	-0.0	0.1	-0.8	-0.5	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.7	-0.1	-1.3	-1.1	-0.2	-0.5	1.2	1.6	0.0	0.0	-1.4	-0.8	-0.7	-0.4	0.1	-0.4	0.2	-1.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.0	-0.0	1.0	1.0	-0.4	-0.1	0.7	-0.6	-0.1	0.3	0.4	0.6	0.6	0.3	1.0	0.1	0.1	1.0
Qualifications: None of the above	1.0	2.1	4.8	1.7	0.5	0.6	1.6	1.4	2.2	-0.4	1.7	-1.6	1.0	-1.1	-1.3	1.9	1.6	1.9	1.4	1.1
Financial difficulties in last 2 years	0.3	0.4	1.8	0.6	0.2	0.1	-0.8	-0.1	-1.2	-1.3	0.5	-0.4	0.1	-0.8	-0.7	0.3	0.6	0.4	0.2	0.1
Mouth/teeth dental problems	1.4	2.1	6.2	-1.4	1.4	1.6	-0.6	-1.5	-1.2	-1.4	-1.3	1.6	-0.1	2.4	2.5	-0.6	1.0	-1.7	-0.6	1.6
Heart attack	0.6	0.8	2.0	0.4	1.0	0.9	0.7	0.6	0.8	1.2	0.4	-0.9	0.1	0.1	-0.3	1.0	1.4	1.0	1.2	1.3
Allergy	0.3	0.7	2.4	0.7	0.6	1.0	1.0	1.4	0.8	0.7	1.0	-0.5	0.3	0.0	0.2	1.5	1.2	0.9	-0.0	0.9
Pain all over the body in last month	0.8	0.9	3.0	-0.6	1.1	0.9	0.5	-0.4	0.7	-0.1	-1.0	0.8	1.6	0.7	0.9	0.3	1.7	-1.4	-0.1	1.0
Diabetes (self-reported)	0.4	0.5	1.2	0.9	-0.6	-1.0	0.8	0.8	-0.2	0.8	0.8	-0.8	-0.0	-0.9	-0.7	0.9	0.0	0.5	1.1	-0.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.2	-0.5	1.6	1.6	-0.3	-0.0	-0.0	0.1	-0.4	0.6	1.0	1.7	1.2	-0.2	1.8	-0.9	0.6	1.7
Medication: Ramipril	0.9	1.2	5.2	1.0	-0.4	-0.8	1.0	0.9	1.2	-0.3	1.5	-1.2	0.9	-0.9	-0.8	1.4	0.3	1.5	2.3	-0.0
Medication: Simvastatin	2.7	3.9	9.5	1.5	-0.7	-1.3	2.8	2.6	0.9	2.6	2.1	-2.2	-1.1	-1.0	-1.2	2.9	0.1	3.0	3.1	-0.1
Fluid intelligence score	0.3	0.6	2.8	-0.7	0.5	0.4	0.3	-0.8	-0.3	-0.4	-1.1	0.2	-1.7	-0.3	0.1	-0.8	-0.9	-0.7	-1.3	-0.0
Illnesses of siblings	1.0	1.4	4.6	-1.5	-0.4	0.0	-1.2	-0.8	-1.2	-0.3	-1.0	1.7	-2.1	1.1	1.7	-1.3	-0.8	-1.5	-0.6	-0.3
Neuroticism score	1.0	2.0	4.8	-1.8	0.8	1.1	-0.8	-1.9	-0.5	0.1	-2.1	2.1	0.3	1.6	2.2	-1.1	1.3	-2.0	-1.3	0.6
Weight	0.1	0.4	2.3	0.4	0.3	0.0	-1.5	-0.4	-0.7	-0.0	-0.4	-0.3	0.6	-0.7	-0.9	-0.6	0.6	-0.1	0.5	0.1
Impedance of arm (right)	0.7	3.5	10.9	1.8	0.6	0.8	3.3	2.7	2.0	1.0	2.4	-2.1	1.1	-0.1	-0.4	2.8	0.4	2.5	2.0	1.5
Arm fat percentage (right)	0.4	1.4	3.8	1.5	1.0	0.7	0.2	1.1	-0.2	-0.5	1.1	-1.5	1.9	-0.9	-1.2	1.1	1.4	1.3	1.9	1.1
Trunk fat-free mass	0.4	2.4	6.4	-1.3	0.1	-0.1	-2.5	-2.0	-1.9	-0.9	-2.3	1.6	-2.2	0.3	0.4	-2.3	-0.2	-1.6	-1.8	-0.8
Hip circumference	0.2	1.0	3.8	1.3	-0.2	-0.4	-0.5	0.8	0.3	0.1	0.7	-1.4	1.9	-1.5	-1.7	0.3	0.0	0.5	1.3	-0.3
Time employed in main current job	0.5	0.6	2.4	0.8	-0.8	-1.3	-0.3	-0.2	0.2	0.2	0.6	-0.4	1.6	-1.1	-1.0	-0.1	-0.4	0.1	0.8	-1.0
Alcohol intake versus 10 years previously	1.1	1.6	3.2	1.8	1.5	1.4	0.6	1.7	0.0	-1.7	1.6	-1.3	1.1	-0.5	-0.9	1.5	1.1	0.8	0.9	1.8
Father’s age at death	0.8	1.1	4.7	-0.1	-1.9	-1.8	-0.4	0.3	-0.7	1.0	0.1	0.8	-2.2	0.4	0.5	-0.0	-1.1	-0.7	0.2	-1.7
Worrier / anxious feelings	0.4	0.7	5.9	-0.7	-0.9	-0.8	0.1	0.2	0.6	2.4	-0.4	0.8	0.3	0.3	1.2	0.5	-0.1	0.0	0.5	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	3.0	0.1	0.5	0.2	0.5	0.9	-0.6	0.2	0.0	-0.1	1.7	-0.0	0.1	0.9	0.4	-0.7	0.6	0.4
Falls in the last year	0.9	1.2	3.5	-1.9	-0.8	-0.3	0.3	-1.3	-0.2	-0.4	-1.0	1.6	-0.9	1.7	1.6	-1.2	0.2	-1.7	-0.5	-0.8
Hair/balding pattern: Pattern 3	1.6	2.4	8.5	-2.0	0.7	1.0	-0.6	-2.5	0.8	0.4	-2.2	1.7	-1.2	2.0	1.9	-1.1	0.6	-2.9	-0.9	0.8
Number of live births	0.4	0.6	1.5	1.1	0.5	0.6	0.6	0.1	0.6	-0.9	0.7	-1.0	0.8	-1.2	-1.0	0.7	0.6	-0.8	0.2	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	2.1	-0.8	-0.6	-0.6	-1.3	-0.4	-1.0	1.4	-1.0	0.2	-0.3	-0.2	0.1	-0.6	-0.2	-1.1	-0.6	-0.5
Pulse rate	0.3	0.5	1.8	-0.2	-1.3	-1.0	-0.3	0.3	-0.7	0.2	-0.3	0.5	0.4	-0.1	0.4	-0.4	-1.3	0.4	-0.4	-1.2
Happiness	0.3	0.4	1.2	-0.7	0.3	0.4	0.4	-0.5	-1.0	0.6	-0.6	0.7	-0.7	1.1	1.0	0.0	0.6	-0.8	0.2	0.0
Noisy workplace	0.5	0.7	2.0	-1.2	-0.9	-0.8	-0.5	-1.1	-0.3	0.2	-1.4	1.1	-0.4	0.5	0.8	-0.9	-0.1	-1.1	0.4	-0.5
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.6	-1.8	-1.4	-0.7	-0.6	-0.9	-1.9	0.2	-1.6	1.6	-2.1	1.7	1.8	-0.6	-1.1	-0.3	-0.1	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.1	-0.1	1.2	1.5	0.2	0.2	-0.3	1.1	-0.5	0.4	0.7	1.2	0.7	0.4	1.2	0.0	-0.2	1.1
Mouth/teeth dental problems: Dentures	0.7	1.1	2.3	1.2	-0.4	-0.4	1.5	1.1	1.0	1.2	1.1	-1.5	0.4	-1.0	-1.5	1.0	-0.2	1.4	1.1	-0.6
Asthma	0.4	0.8	5.8	0.4	-0.4	-0.8	1.2	0.8	0.7	0.2	0.0	-0.7	2.4	-0.5	-0.6	1.1	-0.3	0.8	1.0	-0.2
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.9	-1.7	-0.0	-0.3	-0.9	-0.5	-1.5	-0.3	-1.6	1.7	-1.6	1.7	1.5	-1.5	0.4	0.4	-1.1	-0.5
Medication: Cholesterol lowering	0.9	1.4	4.4	0.3	0.1	-0.1	2.1	1.3	1.2	2.0	0.5	-1.1	-0.2	0.3	0.3	2.0	0.8	1.2	2.0	0.7
Depression (self-reported)	0.3	0.3	1.5	-0.3	0.9	0.5	1.2	0.2	-0.0	0.6	-0.5	0.3	-0.4	0.8	0.6	0.2	0.0	-0.7	-0.3	0.2
Medication: Lansoprazole	1.8	2.1	7.2	1.4	0.6	0.5	1.7	2.1	0.9	-0.0	1.5	-1.3	2.7	-0.4	-0.8	2.5	1.5	0.6	1.6	1.1
Prospective memory result	0.6	0.7	3.9	-0.2	-0.7	-1.0	2.0	0.6	-0.2	-0.8	0.8	0.1	-1.4	0.6	0.2	0.6	-0.8	0.6	0.5	-1.2
Lung cancer (father)	0.5	0.6	2.0	0.4	-0.4	-0.3	1.1	1.4	0.2	1.0	0.5	-0.4	0.3	0.3	0.2	1.4	0.7	0.7	1.2	0.1
Illnesses of mother	0.6	0.7	2.5	-0.2	1.2	1.6	0.5	-0.3	1.3	1.0	-0.3	-0.3	0.5	0.3	0.3	-0.5	1.0	-1.3	0.1	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	1.2	0.3	0.3	0.1	-0.6	-0.0	-0.3	1.1	-0.2	-0.5	0.0	-0.8	-0.5	-0.1	0.5	-0.2	-0.5	0.3
Pulse wave Arterial Stiffness index	1.4	1.6	8.3	0.9	1.5	1.6	0.1	0.8	-0.5	-0.1	0.7	0.2	2.4	0.5	0.8	1.3	2.9	0.9	0.5	1.7
Impedance of arm (left)	0.5	2.5	9.6	1.0	-0.1	0.2	3.1	2.4	2.2	1.2	1.9	-1.8	0.6	-0.0	-0.2	2.2	-0.4	1.9	1.7	0.6
Arm fat mass (right)	0.2	0.6	1.9	0.8	0.5	0.2	-1.1	0.3	-0.6	-0.3	0.2	-0.9	1.4	-0.9	-1.2	0.1	0.9	0.9	1.2	0.4
Trunk predicted mass	0.4	2.4	6.2	-1.3	0.1	-0.1	-2.5	-2.0	-1.9	-1.0	-2.3	1.5	-2.2	0.3	0.4	-2.3	-0.3	-1.6	-1.9	-0.8
Standing height	0.1	0.9	6.5	-0.6	-0.9	-0.8	-0.3	-0.3	0.6	1.2	-1.0	0.1	-2.5	-0.1	0.0	-0.6	-1.4	-0.5	-0.6	-1.1
Length of working week for main job	2.1	2.3	6.7	1.9	-0.0	-0.0	2.2	1.9	1.0	1.3	2.6	-1.7	1.1	-0.7	-0.9	2.0	0.1	2.2	1.7	0.3
Exposure to tobacco smoke at home	0.7	0.8	2.8	0.2	-1.4	-1.1	1.4	1.4	-0.1	1.1	0.5	0.0	-0.3	0.2	0.2	1.1	-0.2	1.7	0.3	-0.9
Breastfed as a baby	0.3	0.4	2.5	0.3	0.1	0.3	-1.0	-0.4	0.0	-1.6	0.2	-0.0	-1.1	-0.5	-0.6	-0.6	0.3	-0.8	0.3	-0.2
Tense / ‘highly strung’	0.6	1.0	3.0	-1.0	1.0	1.3	0.3	0.2	-0.0	-0.0	-1.2	1.5	-0.1	1.4	1.7	-0.6	1.4	-0.7	-0.8	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	3.4	-1.5	0.9	1.0	-1.4	-1.3	-0.7	-0.7	-1.9	1.5	-0.4	1.6	1.7	-0.9	0.9	-0.9	-1.2	0.9
Hair/balding pattern: Pattern 4	0.2	0.6	1.6	-1.0	0.9	0.7	0.0	-0.5	-1.3	-0.4	-1.1	0.8	0.1	0.8	1.3	-0.3	0.2	-0.5	-0.9	0.7
Birth weight of first child	0.3	0.6	1.8	-0.7	-0.7	-1.1	-1.2	0.1	-1.3	1.3	-0.2	0.1	-1.0	-0.6	-0.1	-0.4	-0.8	0.1	0.1	-0.9
Peak expiratory flow (PEF)	0.3	0.7	2.6	0.1	-1.5	-1.6	-0.1	0.4	-0.3	0.9	0.1	-0.3	0.1	-0.9	-0.6	0.2	-1.3	-0.7	0.7	-1.3
Pulse wave reflection index	0.8	1.0	5.0	-0.1	1.4	1.4	-0.4	0.2	-0.9	-0.2	0.3	0.5	1.0	1.1	1.2	1.0	2.2	0.5	0.3	1.4
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	0.6	-0.9	-0.9	0.0	0.3	0.3	0.3	0.2	-0.3	0.8	-0.3	-0.9	-0.4	-0.7	0.0	0.7	-0.9
Loud music exposure frequency	0.3	0.3	1.3	-0.7	0.5	0.1	0.4	-0.9	0.5	0.6	-1.0	-0.2	0.6	-0.0	-0.1	-0.5	-0.1	-1.1	0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	1.4	-0.3	-0.5	-0.1	-0.8	-0.1	-0.7	-0.3	-0.3	-0.0	0.3	-0.0	0.1	-0.1	-1.2	0.6	-0.5	-0.6
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	4.6	1.3	-2.1	-2.0	-0.7	1.6	0.6	1.1	1.2	-1.2	0.7	-2.1	-1.9	0.2	-1.7	0.7	0.9	-1.6
Blood clot in the leg (DVT)	0.2	0.3	2.6	0.6	-0.0	-0.3	0.2	-0.1	0.3	0.2	0.4	-0.6	1.6	-0.9	-0.6	0.1	0.3	0.5	0.4	0.3
Medication: Paracetamol	0.1	0.2	0.4	-0.4	-0.5	-0.3	-0.7	0.3	0.5	0.6	-0.5	0.4	-0.5	0.1	0.2	-0.3	0.0	0.3	-0.6	-0.3
Headache pain in last month	0.3	0.6	2.7	-0.1	0.8	1.0	-0.1	-0.3	1.5	-0.5	-0.6	-0.2	1.6	-0.0	-0.3	-0.6	0.7	0.2	-0.7	0.8
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.8	0.3	-0.4	0.0	-0.5	0.3	-0.4	-0.7	0.3	0.1	0.9	-0.6	-0.5	-0.3	-0.6	0.1	-0.7	-0.3
Glaucoma (self-reported)	1.4	1.7	3.3	-1.1	1.4	1.6	-0.9	-0.9	-1.6	-1.5	-0.9	1.3	-1.8	1.5	1.6	-0.7	1.8	0.1	-0.7	1.4
Gout (self-reported)	0.5	0.7	2.1	0.2	0.1	0.4	0.1	1.5	-1.3	1.3	0.6	0.6	0.7	1.0	1.2	1.1	-0.1	1.4	-0.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	3.0	-1.1	0.5	0.2	-0.9	-1.4	-0.5	-1.5	-1.2	1.3	-0.8	0.8	0.7	-0.8	0.6	-1.1	-1.7	-0.1
Medication: Amlodipine	0.6	0.9	3.0	-1.5	-0.6	-0.5	-0.2	-0.9	-0.5	1.1	-1.1	1.1	0.7	1.5	1.7	-0.1	0.9	-0.4	0.5	-0.2
Medication: Ventolin 100micrograms inhaler	1.0	1.2	4.0	1.2	0.3	-0.2	1.9	1.6	1.0	0.3	1.2	-1.3	0.7	-0.7	-0.6	2.0	0.8	1.3	1.2	0.4
Birth weight	0.5	1.2	3.1	1.2	0.8	0.8	-1.2	-0.1	1.4	0.5	0.7	-1.3	1.2	-1.6	-1.8	-0.2	1.7	0.5	0.5	0.8
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.9	1.2	0.3	-0.0	1.4	1.5	0.4	0.6	1.5	-1.0	0.7	-0.3	-0.6	1.7	0.1	1.5	1.7	0.3
High blood pressure (siblings)	0.4	0.6	4.9	0.5	-0.1	-0.4	0.5	0.4	0.5	-0.2	0.5	-1.1	2.2	-0.8	-1.3	0.4	-0.0	0.8	0.2	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.2	1.2	0.3	0.4	0.1	0.3	0.4	-0.6	1.1	-0.1	-0.4	0.6	-0.3	-0.2	0.1	0.1	-0.1	-0.5	0.3
Body fat percentage	0.7	2.6	7.6	1.9	0.4	0.0	0.6	1.7	0.6	0.8	1.8	-2.1	2.7	-1.3	-1.7	1.9	1.2	1.7	2.8	0.7
Leg fat percentage (right)	0.5	1.7	8.6	1.6	0.3	-0.1	-0.4	1.3	-0.2	0.1	1.3	-1.4	2.9	-1.1	-1.5	1.2	1.1	1.0	2.1	0.5
Arm fat-free mass (right)	0.3	1.6	6.7	-0.9	-0.4	-0.6	-2.6	-1.8	-1.1	-0.6	-1.7	0.8	-1.1	-0.6	-0.5	-2.1	-0.7	-1.2	-1.5	-1.2
Exposure to tobacco smoke outside home	0.7	1.0	3.2	-0.7	-1.3	-1.0	-1.3	-0.4	-0.7	-1.3	-0.4	1.2	-1.8	1.0	0.7	-1.0	-0.1	0.5	-0.7	-1.3
Comparative body size at age 10	0.2	0.4	1.3	1.0	0.9	0.4	0.5	-0.2	0.2	-1.1	0.7	-0.6	1.1	-0.7	-1.0	0.0	0.3	0.5	-0.0	0.3
Number of full brothers	0.4	0.5	1.7	0.1	-0.9	-0.8	0.3	0.2	0.5	0.9	0.4	-0.6	-0.5	-0.9	-0.8	0.6	0.4	0.0	1.3	-0.8
Worry too long after embarrassment	2.0	3.3	8.4	-2.7	-1.7	-1.5	-0.8	-1.3	-1.4	0.0	-2.1	2.9	-0.3	2.2	2.7	-1.7	-0.9	-1.9	-1.7	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	5.5	0.3	2.3	2.3	0.8	-0.3	0.4	-0.1	-0.0	0.2	1.4	1.6	1.3	0.3	1.8	-0.4	-0.1	2.2
Wheeze or whistling in the chest in last year	0.9	1.5	3.9	1.6	-0.6	-0.8	2.0	1.8	0.8	-0.6	1.5	-1.5	0.6	-1.4	-1.4	1.1	-0.9	1.2	1.2	-0.8
Number of children fathered	1.6	1.7	6.2	-0.5	-2.1	-2.2	0.4	0.1	0.8	2.1	-0.5	-0.1	-1.3	-0.9	-0.7	-0.5	-1.6	-1.1	1.2	-2.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.2	0.5	0.2	0.0	-0.6	-0.1	1.1	-0.1	0.5	-0.4	-0.6	-0.3	-0.3	0.1	0.6	0.0	0.5	0.6
Age at first live birth	2.8	5.0	12.5	-3.3	-1.6	-1.3	-1.7	-2.2	-1.9	1.3	-3.1	2.7	-3.5	2.1	2.4	-2.0	-1.2	-2.3	-1.8	-1.7
Pulse wave peak to peak time	1.5	1.8	9.4	-0.6	-1.6	-1.7	0.1	-0.7	0.9	0.1	-0.6	-0.6	-2.4	-0.9	-1.1	-1.1	-3.1	-0.9	-0.4	-1.7
Health satisfaction	0.4	0.6	1.3	0.7	0.8	0.7	0.7	0.9	-0.0	1.0	0.4	-0.7	0.8	-0.3	-0.1	1.2	1.1	0.1	0.8	0.8
Shortness of breath walking on level ground	0.6	0.7	2.6	1.1	0.5	0.1	-0.3	0.9	0.2	-0.0	0.7	-1.0	1.6	-0.9	-1.1	1.1	1.0	0.2	0.8	0.5
Qualifications: College or University degree	0.8	2.6	6.7	-1.6	0.2	0.1	-2.2	-2.0	-1.5	-1.6	-2.2	1.7	-1.4	0.8	0.9	-2.6	-0.7	-1.8	-2.6	-0.3
Eye problems/disorders: None of the above	1.2	1.4	2.7	1.2	-1.1	-1.2	0.8	0.9	1.7	1.5	1.3	-1.4	0.9	-1.4	-1.5	1.3	-0.7	0.8	1.1	-0.7
Mouth/teeth dental problems: Loose teeth	2.6	3.1	10.4	-1.2	-0.0	0.2	-2.8	-2.1	-0.7	-3.0	-2.1	1.4	0.3	-0.4	-0.3	-3.0	-1.0	-0.7	-3.2	-1.1
Emphysema/chronic bronchitis	0.4	0.4	2.1	-0.5	0.2	0.3	0.3	-0.7	0.2	-1.1	-0.6	0.2	-1.4	0.5	0.5	-0.4	0.0	-1.4	0.1	0.1
Medication for pain relief, constipation, heartburn	0.2	0.4	1.5	0.1	0.2	0.2	0.1	-1.2	0.7	0.9	0.0	-0.2	1.2	-0.2	0.1	0.2	-0.0	-1.2	0.9	0.5
Neck or shoulder pain in last month	0.4	0.6	2.4	0.4	0.3	1.0	0.1	0.5	1.5	1.3	-0.6	-0.6	0.2	-0.0	-0.1	0.8	1.3	-0.4	0.2	1.1
Medication: Blood pressure	0.2	0.3	1.4	0.2	1.2	0.9	0.3	-0.3	0.1	0.5	0.2	-0.4	0.1	0.4	0.2	0.5	0.9	0.2	0.8	1.0
Angina (self-reported)	0.4	0.5	1.8	0.5	1.2	0.9	0.8	0.6	0.3	-0.1	0.4	-0.5	-0.5	0.6	0.1	0.8	1.4	0.9	-0.1	1.1
Migraine (self-reported)	5.1	6.4	15.4	-3.2	0.9	1.5	-2.2	-2.9	-2.3	-0.7	-3.9	3.4	-1.4	2.9	3.0	-3.1	0.4	-3.3	-3.0	0.4
Medication: Ibuprofen	1.7	2.1	5.5	-2.0	0.2	-0.0	-1.4	-1.1	-1.7	-0.6	-2.0	1.9	-2.4	1.7	1.7	-2.0	0.4	0.3	-1.4	-0.5
Medication: Allopurinol	0.2	0.2	0.7	0.2	0.3	0.5	0.7	0.7	-0.2	0.4	-0.1	0.2	0.4	0.3	0.4	0.2	-0.7	0.6	-0.8	0.1
Medication: Omeprazole	0.5	0.6	1.5	-0.5	0.2	0.1	-0.6	-0.1	-1.0	-1.2	-0.7	1.1	-1.0	0.7	0.3	-1.1	-0.5	-0.4	-1.2	-0.5
Medication: Seretide 50 evohaler	1.0	1.1	2.8	1.7	0.3	0.0	0.5	1.5	0.3	-0.6	1.1	-1.3	1.4	-1.6	-1.6	1.2	0.6	0.9	0.8	0.5
Mean time to correctly identify matches	0.9	1.8	3.8	-1.1	1.7	1.6	-1.5	-2.0	1.0	-1.4	-1.6	0.7	-1.0	0.2	0.3	-1.8	1.1	-1.2	-1.7	1.1
Heart disease (mother)	0.6	0.8	3.0	-1.1	-0.5	-0.6	-0.8	-0.8	-1.7	-0.8	-0.9	1.3	-0.5	0.7	1.0	-0.5	-0.2	-1.1	-0.5	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.4	-0.6	0.5	0.4	-1.4	-0.6	-1.5	-1.0	-0.2	0.7	0.2	0.7	0.7	-1.5	-0.6	-0.5	-0.8	0.3
Whole body fat mass	0.3	1.3	3.9	1.4	0.4	0.1	-0.2	0.9	0.1	0.6	0.9	-1.6	1.9	-1.3	-1.5	1.0	1.1	1.2	2.0	0.5
Leg fat mass (right)	0.3	1.2	5.1	1.4	0.5	0.1	-0.8	0.8	-0.2	0.1	0.9	-1.2	2.3	-1.1	-1.5	0.7	1.1	0.9	1.6	0.6
Arm predicted mass (right)	0.3	1.7	7.1	-1.1	-0.4	-0.6	-2.7	-1.8	-1.2	-0.3	-2.0	1.0	-0.9	-0.3	-0.2	-2.1	-0.7	-1.3	-1.4	-1.2
Pulse rate, automated reading	0.7	2.3	5.7	2.4	-0.9	-1.0	-0.2	1.6	0.9	0.1	2.1	-1.6	2.1	-2.3	-1.7	0.7	-0.7	2.4	0.7	-0.9
Alcohol intake frequency.	1.0	2.3	7.6	-1.0	1.3	1.6	-1.0	-1.1	-0.6	-2.8	-1.1	1.2	1.8	2.2	1.6	-1.3	0.9	-1.9	-1.6	1.3
Comparative height size at age 10	0.1	0.7	6.2	-0.6	-0.5	-0.6	-0.7	-0.9	0.2	0.3	-0.9	0.3	-2.5	-0.4	-0.1	-0.9	-0.7	-0.9	-0.1	-0.9
Number of full sisters	1.0	1.2	2.8	-1.7	-0.9	-0.6	-1.5	-1.2	-1.1	0.2	-1.5	1.2	-1.7	0.7	0.5	-1.3	-0.5	-1.3	-0.4	-1.0
Suffer from ‘nerves’	0.7	1.1	3.8	-1.0	1.1	1.4	0.4	-2.0	0.6	-0.8	-1.6	0.9	-0.7	0.5	0.9	-0.8	0.5	-1.7	-0.8	0.7
Overall health rating	0.6	1.3	3.5	1.3	-0.3	-0.7	0.7	1.6	0.9	1.5	0.8	-1.6	1.0	-1.4	-1.4	1.1	0.4	0.6	1.9	-0.3
Chest pain or discomfort	0.3	0.4	1.8	-0.1	-0.7	-0.7	0.4	0.5	0.5	1.2	0.6	-0.4	0.1	0.0	0.0	0.9	0.3	-0.7	1.3	-0.6
Had major operations	0.8	0.9	3.5	0.3	0.8	0.9	-1.0	0.6	-1.7	1.6	-0.2	0.4	0.0	0.7	0.7	0.9	1.9	0.5	0.1	1.1
Age at last live birth	0.6	0.8	4.4	-1.1	-0.4	-0.1	-0.2	-0.7	-1.4	0.8	-0.9	0.8	-2.1	1.0	0.9	-0.3	-0.7	-0.7	-0.6	-0.5
Family relationship satisfaction	0.6	0.8	2.0	-0.8	0.6	0.7	0.4	-1.4	-0.2	-0.6	-1.0	1.2	-0.2	1.4	1.4	-0.7	0.9	-1.1	-0.8	0.4
Leg pain on walking	2.6	3.2	5.8	2.4	0.3	0.2	2.1	2.1	2.0	1.7	1.9	-2.3	1.4	-1.5	-1.6	2.4	1.0	2.3	2.3	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.6	0.9	0.8	1.1	0.6	0.9	0.2	1.2	0.8	-0.9	1.6	-0.5	-0.5	1.0	1.2	0.9	1.1	1.0
Commuting to job workplace: Car/motor vehicle	0.6	0.6	2.2	-0.2	-1.4	-1.4	-1.1	0.1	0.5	1.5	-0.4	-0.2	-0.0	-0.6	-0.4	0.0	-0.7	-0.5	0.6	-1.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.7	-0.0	-0.6	-0.6	0.1	-0.1	0.5	-0.8	0.1	0.2	-0.1	-0.6	-0.4	-0.4	-0.8	0.1	-0.7	-0.6
Medication: Aspirin	1.2	1.6	4.3	1.7	0.1	-0.2	0.8	1.4	0.6	-0.9	1.9	-1.8	-0.4	-1.5	-1.9	1.4	0.1	2.1	1.2	0.3
Supplements: Vitamin C	0.7	0.9	3.0	-1.2	-0.1	-0.2	0.6	-1.4	0.5	-0.7	-1.3	0.6	-1.7	0.4	0.6	-1.0	-1.1	-0.9	-1.0	-0.8
Knee pain experienced in last month	1.7	2.6	10.4	0.5	-3.2	-3.2	-0.7	0.1	1.7	1.9	0.2	-0.6	0.4	-1.8	-1.7	-0.2	-1.1	0.3	1.3	-2.7
Hypertension (Self-reported)	0.1	0.2	0.8	-0.6	-0.4	-0.4	0.2	-0.5	-0.3	0.8	-0.2	0.4	0.1	0.8	0.9	0.3	-0.2	0.1	0.8	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	2.4	0.5	0.2	-0.1	0.8	1.1	-0.3	0.6	0.0	0.6	1.6	0.6	0.2	0.1	0.5	0.2	-0.1	-0.2
Illnesses of father: Heart disease	0.5	0.6	2.3	-0.0	1.5	1.2	0.1	-0.0	-1.0	-1.0	-0.3	0.6	0.0	0.9	0.8	-0.5	0.9	0.8	-0.8	0.7
Illnesses of siblings: Diabetes	0.7	0.9	4.6	1.4	0.4	0.3	2.1	0.6	1.2	-0.1	1.0	-1.2	0.3	-0.6	-0.6	1.4	0.2	0.5	0.5	0.6
Smoking status: Previous	0.4	0.6	2.2	-0.7	-1.4	-1.5	0.7	0.3	-0.2	1.4	-0.2	-0.1	-0.2	-0.5	-0.1	0.6	-0.2	0.7	0.7	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.7	-1.3	0.6	0.6	-0.6	-1.3	-1.5	-0.5	-1.6	1.1	-0.8	0.7	0.9	-1.4	-0.7	-1.3	-1.3	0.0
Whole body fat-free mass	0.2	1.4	4.8	-0.7	0.2	-0.0	-2.2	-1.7	-1.5	-0.7	-1.6	0.9	-1.4	-0.1	-0.1	-1.9	-0.1	-1.1	-1.2	-0.6
Leg fat-free mass (right)	0.1	0.4	2.0	0.2	0.4	0.2	-1.4	-0.9	-0.6	-0.3	-0.5	-0.2	-0.6	-0.6	-0.9	-1.0	0.2	-0.1	-0.1	-0.1
Arm fat percentage (left)	0.3	1.1	3.3	1.2	0.8	0.4	0.0	0.9	-0.1	-0.5	0.9	-1.3	1.8	-0.8	-1.2	0.7	1.2	1.1	1.7	0.8
Average weekly red wine intake	0.5	0.7	2.3	1.1	-0.2	-0.7	0.6	-0.0	0.7	-0.9	0.8	-0.6	-1.5	-1.2	-1.5	-0.3	-0.8	-1.1	-0.2	-0.6
Handedness (chirality/laterality): Left-handed	1.1	1.4	7.1	-0.2	0.7	0.6	1.2	0.0	-1.5	-0.8	0.1	1.3	-1.1	2.7	2.1	0.1	1.5	0.1	0.6	0.6
Mood swings	2.5	4.6	8.9	-2.6	1.7	2.0	-2.0	-2.2	-1.7	-1.0	-2.7	3.0	-0.0	2.5	2.8	-1.9	1.6	-2.7	-2.7	1.2
Loneliness, isolation	1.9	2.6	9.0	-1.8	0.1	0.3	-2.1	-3.0	-0.8	-1.9	-2.1	1.6	-0.1	0.5	0.6	-2.2	0.0	-3.0	-1.4	-0.2
Long-standing illness, disability or infirmity	0.3	0.4	4.3	-0.4	0.4	0.1	-0.2	0.5	-0.7	0.0	-0.8	0.2	-2.1	0.5	0.4	-0.2	0.8	-0.3	-0.3	0.2
Ever had bowel cancer screening	1.5	1.8	5.2	-1.8	-1.7	-1.4	-0.9	-1.4	0.8	0.9	-1.3	1.3	-1.2	0.5	0.9	-1.7	-0.8	-2.3	-0.4	-1.7
Diabetes diagnosed by doctor	0.2	0.3	0.8	0.6	0.0	-0.3	0.7	0.7	-0.5	0.7	0.4	-0.3	-0.7	-0.6	-0.2	0.9	0.6	0.3	0.6	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	9.8	-0.2	1.6	1.3	-1.1	-1.8	0.2	-3.1	-0.5	0.5	0.6	-0.2	-0.1	-1.0	1.4	-1.4	0.0	1.2
Friendships satisfaction	0.8	1.0	5.0	-0.9	-1.1	-0.7	1.1	0.2	-0.6	1.0	-0.4	1.2	0.5	2.2	1.8	0.1	-0.6	-0.2	0.1	-0.9
Qualifications: nursing, teaching	1.1	1.6	4.4	-2.0	-1.6	-1.8	-0.8	-1.1	-0.3	1.1	-1.1	0.9	-2.1	0.5	0.7	-0.9	-0.9	-1.3	-0.3	-2.0
Commuting to job workplace: Walk	0.4	0.5	2.9	0.5	-0.1	-0.2	1.7	1.1	0.6	0.1	0.7	-0.6	-0.3	0.0	-0.1	0.8	0.2	1.2	-0.2	0.2
Eye problems/disorders: Cataract	0.3	0.3	1.7	-0.4	0.1	0.4	0.9	0.9	0.1	-0.4	-0.2	0.0	0.4	1.3	0.8	0.5	-0.1	0.4	-0.2	0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.5	0.9	-0.1	-0.4	0.1	0.8	1.3	0.3	0.8	-0.8	-0.2	-1.2	-1.0	0.5	0.0	1.6	0.2	0.2
Medication for cholesterol	0.2	0.3	1.8	0.6	0.8	0.8	-0.5	-0.2	0.3	-0.4	0.1	0.2	0.1	-0.1	-0.3	-0.4	0.9	-1.4	0.2	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.7	0.8	0.7	0.6	0.0	0.6	-0.1	-0.7	0.7	-0.7	-0.8	-0.3	-0.9	-0.3	0.5	0.2	0.1	0.5
Back pain experienced in last month	0.4	0.6	2.4	0.7	0.2	0.3	0.4	1.6	0.2	0.5	0.4	-0.5	1.4	0.1	-0.3	1.4	1.1	0.3	1.1	0.6
Mineral and other dietary supplements	0.6	0.8	2.9	-0.3	1.4	1.7	0.4	0.8	-0.7	0.8	-0.8	0.1	0.6	1.3	1.0	0.2	0.9	0.1	-0.3	1.4
Breast cancer (self-reported)	1.5	1.8	8.1	-0.7	-2.0	-2.3	-0.2	-0.3	-1.8	-1.0	0.3	1.1	-2.0	0.3	0.8	-0.7	-1.6	-0.4	-0.5	-2.8
Asthma (self-reported)	0.5	1.0	4.8	0.7	-0.3	-0.7	1.2	0.9	0.9	0.3	0.3	-1.0	2.2	-0.8	-0.9	1.2	-0.2	1.2	1.3	-0.1
Osteoporosis (self-reported)	0.7	0.9	2.6	1.0	0.8	0.7	0.6	0.9	0.8	-0.5	0.8	-1.2	1.6	-1.2	-0.8	1.6	0.3	-0.3	0.4	1.3
Osteoarthritis (self-reported)	0.6	0.8	1.9	0.4	1.3	1.4	-0.0	0.2	0.8	0.1	-0.4	-1.2	1.0	-1.3	-1.1	0.5	1.3	-0.1	-0.3	1.4
Medication: Aspirin	0.9	1.2	3.8	1.3	0.1	-0.2	0.7	1.4	0.5	-0.8	1.5	-1.6	-0.4	-1.1	-1.6	1.3	0.0	2.0	1.2	0.4
Medication: Gliclazide	0.4	0.4	2.7	0.2	-0.2	-0.5	0.3	0.6	-1.3	1.6	0.3	-0.5	0.5	-0.5	-0.2	0.8	0.3	0.4	1.0	0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	0.2	-0.5	-0.3	0.2	0.5	0.6	0.0	1.1	-0.5	0.9	-0.3	-0.2	0.7	-0.6	-0.8	1.2	0.1
Smoking status: Current	0.3	0.5	2.5	0.6	1.0	1.0	0.3	0.3	0.8	-1.6	0.4	-0.6	0.4	0.1	-0.5	-0.2	0.6	0.7	0.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.5	-0.3	1.4	1.5	-0.8	-0.4	0.2	1.1	-0.7	0.2	0.1	0.4	0.7	0.2	1.9	-1.0	-0.1	1.7
Whole body water mass	0.3	1.5	5.4	-0.8	0.2	0.0	-2.3	-1.8	-1.6	-0.7	-1.7	1.0	-1.7	-0.1	-0.1	-1.9	-0.1	-1.1	-1.3	-0.6
Leg predicted mass (right)	0.1	0.4	2.0	0.2	0.4	0.1	-1.4	-1.0	-0.6	-0.3	-0.6	-0.2	-0.5	-0.6	-0.9	-1.1	0.1	-0.1	-0.2	-0.2
Arm fat mass (left)	0.1	0.5	1.3	0.7	0.3	-0.0	-0.9	0.2	-0.5	-0.3	0.2	-0.8	1.1	-0.9	-1.1	0.0	0.7	0.6	1.1	0.2
Number of self-reported non-cancer illnesses	0.6	1.1	5.0	0.9	1.5	1.3	0.5	0.8	0.8	-0.0	0.3	-1.2	2.2	-0.3	-0.9	0.9	1.1	0.8	0.5	1.6
Average weekly champagne plus white wine intake	0.8	1.1	2.7	-1.4	-1.3	-0.7	-1.2	-1.6	-0.1	0.0	-1.5	1.1	-0.1	0.9	0.8	-1.2	-1.0	-1.6	-0.1	-0.5
Miserableness	0.8	1.4	4.3	-0.5	2.1	2.0	-0.3	-0.7	-0.9	-0.6	-0.9	0.9	1.6	0.7	1.1	-0.2	1.7	-1.7	-0.3	1.6
Guilty feelings	0.9	1.3	2.9	-1.1	1.3	1.7	0.3	-1.1	0.5	-0.2	-1.3	1.5	0.4	1.4	1.6	-0.3	1.4	-1.2	-1.0	1.3
Wears glasses or contact lenses	0.4	0.4	2.6	-0.4	0.5	0.3	0.9	-0.0	-0.1	0.3	-0.3	0.9	-0.2	1.2	1.6	0.0	1.0	0.1	-0.3	0.3
Ever taken oral contraceptive pill	0.2	0.2	0.9	-0.7	-0.1	0.2	-0.4	-0.5	0.2	0.9	-0.8	0.4	-0.8	-0.0	0.5	-0.0	0.2	-0.0	-0.2	0.7
Hearing aid user	1.0	1.1	2.5	1.6	0.7	0.3	1.5	1.4	-0.2	0.0	1.3	-1.2	1.1	-0.6	-1.0	1.3	0.8	0.1	1.6	0.7
Mother’s age at death	0.9	1.1	4.3	-0.5	0.9	0.9	-0.0	-1.4	-0.0	-1.4	-0.9	1.2	-1.0	1.2	1.1	-0.7	0.5	-2.1	-0.9	0.9
Financial situation satisfaction	0.3	0.4	1.7	0.1	0.2	-0.2	-0.2	-0.4	0.9	-0.7	-0.2	-1.0	-0.8	-1.1	-1.3	-0.7	-0.4	0.3	0.1	-0.2
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.8	-0.1	0.3	0.2	0.4	0.3	-0.5	0.1	-0.3	-0.2	-0.9	0.3	0.3	0.4	0.2	0.3	-0.2	0.5
Commuting to job workplace: Public transport	0.2	0.3	2.2	-0.1	0.5	0.4	0.9	0.1	-0.5	-1.5	0.3	0.2	-0.1	0.6	0.2	-0.2	-0.5	-0.1	0.1	0.2
Eye problems/disorders: Glaucoma	2.3	2.7	6.0	-0.9	2.3	2.3	-1.7	-1.7	-1.8	-2.2	-1.3	1.2	-1.0	1.1	1.3	-1.2	2.4	-1.0	-0.9	2.1
Medication: Blood pressure	0.3	0.6	2.6	0.4	-0.0	-0.2	1.6	0.8	0.8	0.5	0.7	-0.7	0.2	-0.3	-0.2	1.1	-0.5	1.5	0.4	0.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.0	0.2	-0.3	-0.3	1.7	0.8	1.6	1.6	0.4	-0.7	1.5	-0.3	-0.1	1.2	0.0	-0.1	1.1	0.1
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.1	0.4	-1.1	-1.5	0.5	-0.2	1.0	0.0	1.1	-0.5	-0.1	-1.1	-0.8	0.8	-0.8	1.0	0.9	-1.0
High cholesterol (Self-reported)	1.1	2.0	7.2	0.2	-0.8	-0.9	2.2	2.0	0.3	2.7	1.2	-0.8	0.8	0.4	0.4	2.3	0.3	1.4	2.3	-0.0
Medication: Bendroflumethiazide	0.9	1.3	3.4	0.2	-1.4	-1.0	1.5	0.8	1.8	1.6	0.6	-1.5	-0.2	-1.0	-0.9	0.8	-1.7	0.6	1.3	-0.9
Medication: Paracetamol	0.4	0.6	1.6	-1.1	-0.2	-0.2	-1.0	-0.5	-0.1	0.2	-1.3	1.0	-1.2	0.7	0.8	-1.1	0.1	-0.1	-1.1	-0.4
Medication: Lisinopril	0.1	0.2	0.4	0.4	0.6	0.5	-0.6	0.4	0.3	-0.0	0.3	-0.2	-0.1	-0.2	-0.6	-0.2	-0.6	0.6	-0.3	0.4
Medication: Atorvastatin	1.1	1.4	4.6	0.3	2.1	1.9	0.9	0.8	0.4	0.0	0.4	-0.3	2.0	0.9	0.7	0.8	1.7	0.2	0.0	2.1
Illnesses of father: High blood pressure	0.3	0.4	2.1	0.5	-0.2	-0.4	1.3	1.4	0.6	0.5	0.6	0.2	0.2	-0.3	-0.3	0.8	-0.3	0.7	-0.6	-0.2
Alcohol drinker status: Never	2.4	2.9	11.5	-1.9	-0.3	-0.1	-1.8	-1.9	-1.5	-3.4	-1.5	2.3	-0.3	1.4	1.4	-2.6	-0.3	-1.1	-2.2	-0.9
Ever smoked	0.4	0.7	2.7	-0.1	-1.0	-1.0	1.3	0.9	0.6	0.9	0.3	-0.2	-0.9	0.0	-0.1	0.6	0.0	1.6	0.9	-1.0
Basal metabolic rate	0.2	0.9	4.3	-0.4	0.3	0.0	-2.1	-1.3	-1.4	-0.5	-1.3	0.5	-0.9	-0.3	-0.3	-1.5	0.0	-0.7	-0.7	-0.4
Leg fat percentage (left)	0.6	2.1	8.2	1.9	0.0	-0.4	-0.1	1.6	0.1	0.5	1.6	-1.8	2.9	-1.5	-1.9	1.5	0.9	1.1	2.4	0.2
Arm fat-free mass (left)	0.2	1.1	5.6	-0.4	0.1	-0.2	-2.4	-1.5	-1.3	-0.5	-1.5	0.6	-1.0	-0.6	-0.6	-1.6	-0.1	-0.9	-1.1	-0.7
Number of operations (self-reported)	0.3	0.4	1.2	0.7	-0.2	-0.3	1.0	1.0	0.1	0.1	0.4	-0.4	1.1	-0.2	-0.2	1.1	0.8	-0.4	0.7	-0.2
Average weekly beer plus cider intake	0.2	0.3	1.4	1.0	-0.2	-0.3	0.0	0.2	-0.0	-0.0	1.2	-0.7	-0.4	-0.4	-0.5	0.3	-0.5	0.9	-0.6	-0.6
Irritability	0.8	1.3	5.9	-1.7	0.4	0.7	0.5	-0.8	-0.5	0.6	-1.1	1.7	-0.8	2.0	2.4	0.3	1.2	-0.4	-0.1	0.4
Risk taking	0.6	0.8	2.9	-1.2	1.0	1.1	-1.2	-1.5	0.5	-0.1	-1.7	0.5	-0.0	0.4	0.5	-0.9	0.4	-0.6	-1.4	0.4
Ever had prostate specific antigen (PSA) test	0.9	1.0	3.1	0.8	0.8	0.9	-0.1	0.7	0.4	1.8	0.9	-0.4	1.1	0.2	0.1	1.2	1.3	1.3	1.4	1.4
Fractured/broken bones in last 5 years	1.7	2.2	10.5	1.3	1.3	1.2	1.7	1.8	0.8	0.3	1.6	-0.4	3.2	0.5	0.4	2.1	1.9	0.4	0.7	1.6
Age started oral contraceptive pill	0.4	0.5	2.3	0.2	-1.1	-0.9	0.2	0.7	0.5	1.5	0.8	-0.3	-0.2	0.1	-0.0	0.8	-0.6	0.9	0.4	-0.8
Diastolic blood pressure, automated reading	0.5	1.5	4.7	1.4	-1.3	-1.8	0.3	0.7	0.5	0.1	1.2	-1.1	-0.4	-2.2	-1.7	-0.0	-1.1	1.5	1.0	-1.6
Ever depressed for a whole week	0.4	0.4	1.6	0.7	-0.4	-0.8	-0.4	0.0	1.3	-0.4	0.4	-0.8	0.3	-1.0	-1.2	0.3	-0.5	0.6	0.4	-0.5
Unable to work because of sickness or disability	0.5	0.7	4.2	0.3	1.3	1.2	-0.1	-0.8	0.4	-2.1	0.1	-0.0	0.7	0.4	-0.1	-0.4	0.9	-1.0	-0.8	0.7
Commuting to job workplace: Cycle	0.2	0.3	1.2	-0.4	-0.6	-0.3	0.7	-0.9	0.9	-0.5	0.0	-0.0	-0.5	-0.0	0.0	-0.2	-1.1	-0.4	-0.2	-0.5
Myopia	0.2	0.3	1.1	-0.0	-0.3	-0.4	0.4	1.0	-0.8	1.1	0.1	0.1	-0.6	0.3	0.3	0.7	-0.1	0.3	0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.7	-0.8	-0.1	-0.0	-1.4	-1.0	-0.7	-1.2	-1.2	1.0	-0.6	0.1	-0.0	-1.8	-0.6	-1.5	-1.9	-0.5
Cholesterol lowering medication	1.5	2.3	5.5	1.3	1.0	0.4	1.4	2.2	-0.8	1.9	1.7	-1.2	1.1	-0.3	-0.4	2.3	1.8	2.2	1.6	1.5
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.2	-0.8	0.0	-0.1	-1.5	-0.5	-1.2	-1.8	-1.1	1.3	-1.1	0.6	0.2	-1.7	-0.6	-0.6	-1.8	-0.8
Pain experienced in last month	0.9	1.6	7.8	-1.3	-0.6	-1.0	-0.6	-0.9	-2.1	-0.6	-0.3	0.9	-2.8	0.7	1.0	-0.9	-1.9	0.4	-1.2	-1.2
Supplements: Calcium	0.6	0.6	1.5	1.0	-0.6	-0.9	0.7	0.5	0.7	0.0	0.8	-1.0	0.5	-1.1	-1.1	0.5	-0.7	1.2	0.8	-0.6
Basal cell carcinoma (self-reported)	0.8	0.9	3.3	1.1	-0.9	-1.4	-0.4	0.7	0.0	-0.6	0.8	-0.9	0.7	-1.1	-1.8	-0.6	-1.3	1.0	-0.2	-1.2
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.8	0.4	1.0	1.0	0.6	0.4	0.9	1.0	0.3	-0.9	0.0	0.1	-0.2	0.8	1.3	0.9	1.1	1.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	2.1	0.3	-0.3	-0.4	0.1	-0.2	0.2	0.5	0.2	-0.5	1.4	-0.8	-0.5	-0.1	0.4	0.2	0.5	0.2
Heart disease (siblings)	0.6	0.7	1.7	-1.0	0.8	0.4	-0.1	-1.2	-0.8	-0.5	-1.2	1.3	0.5	0.8	0.9	-0.5	1.2	-0.9	-0.7	0.4
Alcohol drinker status: Previous	0.6	0.7	2.1	0.1	0.7	0.4	0.5	0.0	-0.7	-1.4	-0.2	1.0	0.8	1.5	0.9	-0.2	0.9	-0.9	-1.3	0.2
Pack years of smoking	1.0	1.4	4.7	2.2	0.9	0.7	-0.4	0.1	1.2	-0.4	1.4	-1.6	1.5	-1.7	-2.1	0.3	0.9	0.6	0.8	0.7
Impedance of whole body	0.6	3.2	7.9	1.4	-0.8	-0.5	2.8	2.8	2.4	1.9	2.3	-2.1	1.1	-0.6	-0.6	2.7	-0.8	1.7	1.9	0.1
Leg fat mass (left)	0.3	1.3	4.8	1.5	0.4	-0.0	-0.8	0.9	-0.2	0.4	1.0	-1.3	2.2	-1.2	-1.6	0.8	1.1	1.0	1.7	0.5
Arm predicted mass (left)	0.2	1.2	5.1	-0.6	-0.0	-0.4	-2.2	-1.5	-1.5	-0.5	-1.6	0.7	-1.2	-0.5	-0.4	-1.6	-0.2	-1.1	-1.2	-0.9