[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr1:23,431,777-24,861,704

Best TWAS P=5.27e-08 · Best GWAS P=3.29e-07 conditioned to 0.0558

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cortex	HMGCL	0.22	0.09	enet	12	0.12	3.2e-04	4.5	5.4	5.3e-08	0.68	0.03	0.82	TRUE
2	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FUCA1	0.20	0.15	blup	35	0.14	1.5e-05	4.6	5.3	1.2e-07	0.46	0.00	0.95	FALSE