Best TWAS P=5.27e-08 · Best GWAS P=3.29e-07 conditioned to 0.0558
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cortex | HMGCL | 0.22 | 0.09 | enet | 12 | 0.12 | 3.2e-04 | 4.5 | 5.4 | 5.3e-08 | 0.68 | 0.03 | 0.82 | TRUE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | FUCA1 | 0.20 | 0.15 | blup | 35 | 0.14 | 1.5e-05 | 4.6 | 5.3 | 1.2e-07 | 0.46 | 0.00 | 0.95 | FALSE |