Best TWAS P=1.31e-07 · Best GWAS P=4.25e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PSMD5 | 0.23 | 0.22 | lasso | 7 | 0.23 | 2.4e-27 | 4.9 | 5.2 | 2.0e-07 | 0.97 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Muscle Skeletal | PSMD5 | 0.31 | 0.31 | enet | 20 | 0.34 | 6.0e-34 | 5.1 | 5.3 | 1.3e-07 | 0.96 | 0.00 | 0.99 | TRUE |
| 3 | GTEx | Small Intestine Terminal Ileum | PSMD5-AS1 | 0.49 | 0.48 | enet | 14 | 0.41 | 2.5e-10 | 4.8 | 5.2 | 2.2e-07 | 0.97 | 0.00 | 0.99 | FALSE |
| 4 | METSIM | Adipose | PHF19 | 0.07 | 0.01 | bslmm | 374 | 0.01 | 2.3e-02 | 4.8 | -5.2 | 2.2e-07 | -0.64 | 0.02 | 0.94 | FALSE |
| 5 | YFS | Blood | PHF19 | 0.05 | 0.03 | enet | 21 | 0.04 | 2.9e-14 | 4.2 | -5.2 | 1.8e-07 | -0.79 | 0.08 | 0.86 | FALSE |
| 6 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | LOC253039 | 0.24 | 0.26 | lasso | 2 | 0.23 | 5.7e-07 | 5.0 | 5.1 | 2.8e-07 | 0.99 | 0.00 | 0.99 | FALSE |