Best TWAS P=1.49e-17 · Best GWAS P=2.08e-30 conditioned to 2.14e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | RTKN2 | 0.02 | 0.00 | bslmm | 484 | 0.00 | 3.9e-02 | 7.67 | 8.5 | 1.5e-17 | 0.05 | 0.25 | 0.01 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARID5B | 0.05 | 0.05 | lasso | 2 | 0.04 | 3.7e-05 | 6.74 | -6.5 | 1.1e-10 | -0.54 | 0.71 | 0.11 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ARID5B | 0.05 | 0.00 | blup | 112 | 0.02 | 2.7e-03 | -0.63 | 5.4 | 7.8e-08 | 0.40 | 0.03 | 0.10 | FALSE |