[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr2:24,324,172-25,837,917

Best TWAS P=4.54e-13 · Best GWAS P=7.57e-11 conditioned to 0.848

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADCY3 0.16 0.12 lasso 10 0.14 3.2e-17 6.4 -7.2 4.5e-13 -0.89 0.01 0.99 TRUE
2 CommonMind Brain Pre-frontal Cortex CENPO 0.07 0.03 bslmm 322 0.03 7.0e-05 4.0 -5.9 4.8e-09 -0.49 0.06 0.90 FALSE
3 GTEx Artery Tibial ADCY3 0.21 0.14 lasso 6 0.15 4.3e-12 4.8 5.6 1.9e-08 0.70 0.97 0.03 FALSE
4 GTEx Artery Tibial RP11-443B20.1 0.17 0.08 enet 40 0.09 8.2e-08 4.8 5.5 4.2e-08 0.59 0.55 0.41 FALSE
5 GTEx Cells EBV-transformed lymphocytes RP11-443B20.1 0.13 0.13 enet 9 0.05 9.2e-03 5.0 -5.8 8.3e-09 -0.93 0.02 0.94 FALSE
6 GTEx Nerve Tibial ADCY3 0.09 0.05 enet 6 0.03 2.2e-03 4.8 -6.5 1.0e-10 -0.92 0.02 0.98 FALSE
7 GTEx Nerve Tibial RP11-443B20.1 0.07 0.03 enet 6 0.02 1.1e-02 4.8 -6.0 1.8e-09 -0.82 0.04 0.95 FALSE
8 GTEx Whole Blood ADCY3 0.23 0.24 enet 24 0.27 5.5e-25 5.2 6.0 2.5e-09 0.87 0.94 0.06 FALSE
9 GTEx Whole Blood RP11-443B20.1 0.21 0.17 enet 32 0.20 1.8e-18 5.0 6.0 2.7e-09 0.87 0.77 0.23 FALSE
10 ROSMAP Brain Pre-frontal Cortex ADCY3 0.17 0.26 enet 32 0.26 6.8e-33 5.2 -5.9 3.9e-09 -0.90 0.86 0.14 FALSE
11 YFS Blood ADCY3 0.07 0.02 bslmm 343 0.04 7.3e-14 6.5 -6.7 1.8e-11 -0.63 0.01 0.99 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma ADCY3 0.05 0.03 blup 81 0.03 5.0e-07 2.5 -5.5 4.2e-08 -0.51 0.40 0.57 FALSE