Best TWAS P=6.22e-09 · Best GWAS P=1.41e-06 conditioned to 0.0198
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | LMF1 | 0.36 | 0.23 | enet | 44 | 0.28 | 3.6e-21 | -4.8 | -5.2 | 2.5e-07 | 0.84 | 0.00 | 0.99 | FALSE |
| 2 | YFS | Blood | SOX8 | 0.05 | 0.00 | bslmm | 406 | 0.02 | 5.6e-07 | -4.0 | 5.8 | 6.2e-09 | -0.48 | 0.04 | 0.52 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | LMF1 | 0.10 | 0.02 | blup | 99 | 0.03 | 6.1e-03 | -2.0 | -5.1 | 3.0e-07 | 0.65 | 0.01 | 0.73 | FALSE |