Best TWAS P=5.6e-10 · Best GWAS P=3.26e-08 conditioned to 0.585
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | RBM39 | 0.05 | 0.05 | blup | 293 | 0.06 | 2.6e-19 | 5.1 | 6.2 | 5.6e-10 | 0.84 | 0.07 | 0.93 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FER1L4 | 0.05 | 0.06 | lasso | 5 | 0.05 | 1.2e-06 | 5.4 | -5.4 | 6.8e-08 | -0.85 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | NFS1 | 0.11 | 0.00 | blup | 47 | 0.04 | 1.8e-02 | 5.4 | 5.8 | 5.2e-09 | 0.91 | 0.01 | 0.60 | FALSE |