# | panel | tissue | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | BSLMM R2 | LASSO R2 | eQTL P | BLUP P | ENET P | BSLMM P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | 0.1652 | 0.0816 | 5.0e-04 | 0.101 | NA | 0.091 | NA | 0.107 | 1.7e-04 | NA | 3.7e-04 | NA | 1.2e-04 |
2 | GTEx | Artery Aorta | 0.0880 | 0.0500 | 9.4e-03 | -0.003 | NA | -0.005 | NA | -0.003 | 5.1e-01 | NA | 9.1e-01 | NA | 5.4e-01 |
3 | GTEx | Esophagus Muscularis | 0.1070 | 0.0370 | 3.2e-06 | 0.135 | NA | 0.128 | NA | 0.128 | 1.4e-08 | NA | 3.4e-08 | NA | 3.6e-08 |
4 | GTEx | Muscle Skeletal | 0.0554 | 0.0215 | 4.1e-06 | 0.074 | NA | 0.061 | NA | 0.072 | 9.3e-08 | NA | 1.2e-06 | NA | 1.4e-07 |
5 | GTEx | Nerve Tibial | 0.0766 | 0.0291 | 5.8e-06 | 0.095 | NA | 0.089 | NA | 0.089 | 2.9e-07 | NA | 7.6e-07 | NA | 7.7e-07 |
6 | GTEx | Skin Sun Exposed Lower leg | 0.0630 | 0.0250 | 1.6e-05 | 0.096 | NA | 0.081 | NA | 0.083 | 2.6e-08 | NA | 2.9e-07 | NA | 2.4e-07 |
7 | ROSMAP | Brain Pre-frontal Cortex | 0.0377 | 0.0171 | 2.0e-04 | 0.041 | 0.032 | 0.026 | 0.031 | 0.029 | 4.7e-06 | 4.9e-05 | 2.4e-04 | 6.4e-05 | 1.1e-04 |
8 | TCGA | Kidney Renal Clear Cell Carcinoma | 0.0489 | 0.0253 | 1.5e-06 | 0.062 | 0.037 | 0.044 | NA | 0.053 | 1.6e-07 | 4.8e-05 | 9.7e-06 | NA | 1.2e-06 |
9 | TCGA | Thyroid Carcinoma | 0.0910 | 0.0590 | 1.8e-04 | 0.046 | 0.036 | 0.024 | NA | 0.036 | 2.7e-05 | 1.9e-04 | 1.8e-03 | NA | 1.9e-04 |
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Sitting height | 31.7 | 225.3 | 396.0 | -18.0 | -10.5 | -14.4 | -14.0 | -14.3 | -13.2 | -9.6 | -19.9 | 18.0 |
Trunk predicted mass | 30.0 | 171.4 | 269.0 | -15.0 | -10.6 | -13.5 | -12.8 | -13.4 | -12.8 | -9.9 | -16.4 | 12.2 |
Trunk fat-free mass | 29.5 | 169.4 | 265.7 | -15.0 | -10.5 | -13.4 | -12.7 | -13.3 | -12.7 | -9.8 | -16.3 | 12.2 |
Arm fat-free mass (right) | 28.1 | 144.1 | 213.2 | -13.8 | -9.7 | -12.7 | -11.9 | -12.5 | -12.0 | -9.8 | -14.6 | 9.9 |
Arm predicted mass (right) | 27.7 | 141.5 | 209.8 | -13.7 | -9.7 | -12.6 | -11.7 | -12.3 | -11.9 | -9.8 | -14.5 | 10.0 |
Whole body fat-free mass | 27.7 | 158.0 | 243.4 | -14.4 | -10.3 | -13.2 | -12.4 | -12.9 | -12.4 | -9.5 | -15.6 | 11.3 |
Whole body water mass | 27.7 | 158.0 | 240.2 | -14.3 | -10.3 | -13.3 | -12.4 | -13.0 | -12.5 | -9.6 | -15.5 | 11.1 |
Height | 26.9 | 517.8 | 846.8 | -26.3 | -19.7 | -22.6 | -21.7 | -22.6 | -21.3 | -14.2 | -29.1 | 24.2 |
Standing height | 25.7 | 255.2 | 430.8 | -18.7 | -13.2 | -15.8 | -14.7 | -15.5 | -14.6 | -9.9 | -20.8 | 18.0 |
Arm predicted mass (left) | 25.7 | 130.8 | 196.0 | -13.3 | -9.0 | -12.2 | -11.4 | -11.8 | -11.3 | -9.0 | -14.0 | 9.8 |
Arm fat-free mass (left) | 25.4 | 129.1 | 193.6 | -13.2 | -9.0 | -12.1 | -11.2 | -11.7 | -11.3 | -9.0 | -13.9 | 9.8 |
Basal metabolic rate | 24.7 | 136.6 | 204.5 | -13.3 | -9.5 | -12.6 | -11.7 | -12.1 | -11.6 | -8.9 | -14.3 | 10.1 |
Leg predicted mass (right) | 24.1 | 128.4 | 190.4 | -12.8 | -9.7 | -12.2 | -11.4 | -11.8 | -11.4 | -8.3 | -13.8 | 9.6 |
Leg fat-free mass (right) | 24.0 | 128.3 | 190.4 | -12.8 | -9.6 | -12.2 | -11.4 | -11.8 | -11.4 | -8.3 | -13.8 | 9.6 |
Leg fat-free mass (left) | 22.4 | 118.8 | 176.9 | -12.2 | -9.0 | -11.9 | -11.0 | -11.3 | -10.9 | -8.0 | -13.3 | 9.4 |
Leg predicted mass (left) | 22.3 | 118.4 | 176.9 | -12.2 | -9.0 | -11.8 | -11.0 | -11.3 | -10.9 | -7.9 | -13.3 | 9.4 |
Comparative height size at age 10 | 17.4 | 96.0 | 153.8 | -10.8 | -8.7 | -10.5 | -9.8 | -9.8 | -9.3 | -5.2 | -12.4 | 10.2 |
Weight | 13.0 | 63.8 | 87.9 | -8.9 | -6.3 | -9.3 | -8.4 | -8.4 | -8.1 | -6.4 | -9.4 | 6.1 |
Hand grip strength (right) | 9.6 | 26.2 | 49.1 | -6.2 | -3.3 | -4.9 | -4.6 | -4.9 | -4.4 | -2.6 | -7.0 | 6.5 |
Forced expiratory volume in 1-second (FEV1), predicted | 9.6 | 20.0 | 34.4 | -5.0 | -3.9 | -4.3 | -4.2 | -4.3 | -4.1 | -2.3 | -5.9 | 5.3 |
Lung FVC | 8.2 | 41.8 | 72.1 | 8.4 | 2.2 | 5.6 | 6.3 | 6.1 | 5.5 | 4.6 | 8.5 | -8.3 |
Impedance of leg (right) | 7.5 | 36.2 | 46.5 | 6.6 | 5.5 | 6.5 | 6.2 | 6.6 | 6.6 | 5.0 | 6.8 | -3.5 |
Hip circumference | 7.1 | 30.7 | 45.4 | -6.0 | -3.9 | -6.7 | -6.0 | -5.9 | -5.7 | -4.8 | -6.3 | 3.9 |
Peak expiratory flow (PEF) | 7.1 | 16.4 | 25.9 | -4.5 | -3.9 | -4.1 | -4.0 | -3.9 | -3.6 | -2.3 | -5.1 | 4.4 |
Impedance of leg (left) | 6.8 | 32.9 | 43.8 | 6.1 | 5.1 | 6.3 | 5.9 | 6.2 | 6.2 | 4.7 | 6.6 | -3.9 |
Intelligence (Savage-Jansen 2018) | 6.4 | 19.6 | 29.2 | -4.5 | -3.2 | -4.3 | -4.8 | -4.6 | -4.1 | -5.0 | -5.4 | 3.6 |
Tanning | 6.3 | 76.4 | 153.8 | -12.4 | -3.2 | -2.0 | -8.6 | -9.0 | -9.0 | -8.8 | -11.2 | 9.0 |
Mean time to correctly identify matches | 6.1 | 11.7 | 16.4 | 3.6 | 3.5 | 3.2 | 3.2 | 3.6 | 3.3 | 3.6 | 4.1 | -2.5 |
Fluid intelligence score | 5.7 | 11.8 | 16.4 | -3.3 | -2.4 | -3.5 | -4.0 | -3.7 | -3.4 | -4.0 | -3.8 | 2.3 |
Impedance of whole body | 5.7 | 29.1 | 36.0 | 5.9 | 4.2 | 5.8 | 5.6 | 6.0 | 6.0 | 5.7 | 5.9 | -2.6 |
Qualifications: CSEs or equivalent | 5.4 | 7.1 | 11.5 | 3.4 | 1.5 | 2.8 | 2.5 | 2.5 | 2.4 | 2.9 | 3.0 | -2.6 |
Impedance of arm (right) | 5.4 | 25.2 | 39.6 | 5.5 | 3.6 | 5.2 | 5.1 | 5.5 | 5.7 | 6.3 | 5.1 | -1.6 |
Myopia | 5.4 | 7.9 | 15.0 | -3.6 | -1.8 | -2.3 | -2.4 | -2.6 | -2.2 | -2.7 | -3.9 | 3.2 |
LDL Cholesterol | 5.1 | 8.0 | 10.9 | 2.4 | 2.6 | 3.2 | 3.3 | 3.1 | 3.0 | 3.0 | 3.0 | -1.7 |
Knee pain experienced in last month | 5.1 | 7.9 | 17.6 | 3.3 | 1.4 | 1.8 | 2.4 | 2.6 | 2.3 | 1.9 | 4.0 | -4.2 |
Ovarian Cancer | 5.0 | 6.6 | 9.1 | 3.0 | 2.9 | 2.9 | 2.6 | 2.9 | 2.9 | 2.2 | 2.0 | 0.5 |
HDL Cholesterol | 5.0 | 8.4 | 12.0 | 2.8 | 2.3 | 3.5 | 3.4 | 3.1 | 3.1 | 2.9 | 3.2 | -1.1 |
Time employed in main current job | 5.0 | 5.8 | 8.1 | 2.4 | 2.9 | 2.5 | 2.5 | 2.7 | 2.8 | 2.6 | 2.1 | 0.3 |
Waist circumference | 4.8 | 17.4 | 28.5 | -4.2 | -3.7 | -5.3 | -4.7 | -4.5 | -4.5 | -4.3 | -3.9 | 0.8 |
Medication: Ventolin 100micrograms inhaler | 4.7 | 6.1 | 9.3 | -3.0 | -2.7 | -2.9 | -2.5 | -2.5 | -2.4 | -2.5 | -2.2 | 0.7 |
Respiratory disease | 4.6 | 10.1 | 14.6 | -3.7 | -3.4 | -3.8 | -3.2 | -3.4 | -3.5 | -3.2 | -2.8 | 0.3 |
Ulcerative Colitis | 4.5 | 6.5 | 9.1 | -2.8 | -2.6 | -2.3 | -2.9 | -3.0 | -3.0 | -2.0 | -2.5 | 1.0 |
Verbal and Numeric Reasoning (VNR) | 4.4 | 10.5 | 14.4 | -3.5 | -2.0 | -3.4 | -3.5 | -3.4 | -3.2 | -3.8 | -3.6 | 2.4 |
Hand grip strength (left) | 4.4 | 11.7 | 29.7 | -4.1 | -1.5 | -3.1 | -2.6 | -2.8 | -2.5 | -0.8 | -5.0 | 5.5 |
Breast Cancer | 4.3 | 10.5 | 17.0 | 2.8 | 3.7 | 4.1 | 3.6 | 3.7 | 3.9 | 2.7 | 2.3 | 1.0 |
Number of incorrect matches in round | 4.3 | 7.1 | 8.7 | 2.8 | 2.4 | 2.8 | 2.8 | 2.9 | 2.7 | 3.0 | 2.8 | -1.4 |
Forced expiratory volume in 1-second (FEV1) | 4.3 | 14.5 | 25.5 | -3.3 | -5.0 | -4.0 | -3.6 | -3.8 | -3.7 | -3.1 | -4.4 | 2.8 |
Reaction Time | 4.2 | 8.0 | 12.8 | 3.4 | 2.6 | 2.4 | 2.4 | 2.8 | 2.7 | 2.9 | 3.6 | -2.4 |
Commuting to job workplace: Walk | 4.2 | 4.6 | 6.7 | -2.5 | -1.9 | -1.7 | -1.6 | -2.2 | -2.1 | -2.1 | -2.6 | 2.3 |
Medication: Simvastatin | 4.1 | 6.1 | 9.1 | 2.0 | 2.9 | 2.7 | 2.7 | 2.8 | 3.0 | 2.9 | 1.5 | 0.9 |
Impedance of arm (left) | 4.1 | 18.9 | 28.4 | 5.0 | 2.8 | 4.5 | 4.4 | 4.8 | 4.9 | 5.3 | 4.5 | -1.4 |
Alcohol intake versus 10 years previously | 4.0 | 6.0 | 8.3 | -2.2 | -2.8 | -2.6 | -2.7 | -2.8 | -2.9 | -2.3 | -2.5 | 0.2 |
Forced expiratory volume in 1-second (FEV1), Best measure | 4.0 | 12.7 | 22.4 | -3.2 | -4.7 | -3.6 | -3.2 | -3.5 | -3.5 | -2.8 | -4.3 | 2.7 |
Length of working week for main job | 3.9 | 4.3 | 6.9 | -2.3 | -1.5 | -2.0 | -2.1 | -2.1 | -1.9 | -2.2 | -2.6 | 1.8 |
Type 2 Diabetes (T2D) (2012) | 3.8 | 4.4 | 6.2 | -2.5 | -1.1 | -2.2 | -2.1 | -2.0 | -2.5 | -2.4 | -2.1 | 1.5 |
Mood swings | 3.8 | 6.9 | 11.4 | -2.2 | -2.9 | -3.4 | -2.7 | -2.8 | -2.8 | -3.3 | -1.8 | -0.4 |
High cholesterol (Self-reported) | 3.8 | 6.8 | 12.0 | 2.5 | 3.5 | 2.8 | 2.6 | 2.9 | 3.1 | 2.4 | 2.1 | -0.2 |
Trunk fat mass | 3.7 | 15.7 | 28.1 | -4.2 | -3.1 | -5.3 | -4.5 | -4.2 | -4.1 | -3.2 | -4.2 | 1.9 |
Asthma | 3.7 | 7.4 | 9.7 | -3.1 | -2.8 | -3.1 | -2.9 | -2.9 | -2.9 | -2.7 | -2.5 | 0.9 |
Asthma (self-reported) | 3.7 | 7.4 | 9.4 | -2.9 | -3.0 | -3.1 | -3.0 | -3.0 | -2.9 | -2.7 | -2.4 | 0.6 |
Alzheimer’s Disease (including proxy) | 3.6 | 5.2 | 9.4 | 3.1 | 1.9 | 2.3 | 2.4 | 2.4 | 2.1 | 2.0 | 2.5 | -1.5 |
Breast cancer (self-reported) | 3.3 | 3.9 | 6.0 | -2.0 | -2.2 | -2.5 | -1.9 | -2.1 | -2.3 | -2.3 | -1.4 | -0.2 |
Hair Pigment | 3.2 | 90.0 | 158.8 | 12.6 | 3.1 | 2.7 | 10.1 | 9.9 | 9.7 | 10.1 | 12.5 | -9.0 |
Alcohol usually taken with meals | 3.2 | 5.2 | 16.1 | -2.0 | -0.6 | -1.8 | -1.7 | -1.6 | -1.3 | -2.7 | -2.9 | 4.0 |
Coronary Artery Disease (CAD) | 3.1 | 3.7 | 7.0 | -1.5 | -1.5 | -2.6 | -2.4 | -2.3 | -2.2 | -2.0 | -1.4 | -0.1 |
Illnesses of mother | 3.1 | 3.9 | 7.3 | -1.9 | -2.7 | -1.6 | -2.0 | -2.2 | -2.3 | -1.7 | -1.9 | 0.6 |
Forced vital capacity (FVC), Best measure | 3.0 | 10.9 | 20.1 | -3.0 | -4.5 | -3.5 | -2.8 | -3.1 | -3.1 | -2.2 | -4.1 | 2.9 |
Migraine (self-reported) | 3.0 | 3.8 | 9.0 | -1.5 | -1.8 | -2.2 | -2.0 | -2.0 | -1.9 | -3.0 | -1.7 | 0.4 |
Chest pain or discomfort | 3.0 | 4.3 | 7.1 | -2.7 | -1.4 | -2.2 | -2.3 | -2.0 | -1.8 | -2.3 | -2.2 | 1.4 |
Arm fat mass (left) | 3.0 | 12.2 | 22.0 | -3.5 | -2.6 | -4.7 | -4.1 | -3.8 | -3.8 | -3.4 | -3.3 | 0.7 |
Qualifications: O levels/GCSEs or equivalent | 2.9 | 4.7 | 8.1 | -2.1 | -1.9 | -2.8 | -2.2 | -2.4 | -2.4 | -1.7 | -2.3 | 1.1 |
Wheeze or whistling in the chest in last year | 2.9 | 5.2 | 6.9 | -2.6 | -2.3 | -2.4 | -2.3 | -2.5 | -2.4 | -2.5 | -2.4 | 0.9 |
Forced vital capacity (FVC) | 2.8 | 10.9 | 20.3 | -2.8 | -4.5 | -3.5 | -2.9 | -3.2 | -3.1 | -2.2 | -4.0 | 2.8 |
Diabetes (self-reported) | 2.8 | 4.4 | 7.1 | -1.8 | -1.7 | -2.0 | -2.4 | -2.2 | -1.9 | -2.2 | -2.7 | 1.7 |
Whole body fat mass | 2.8 | 11.7 | 21.8 | -3.6 | -2.4 | -4.7 | -3.9 | -3.6 | -3.6 | -3.1 | -3.5 | 1.3 |
Alzheimer’s Disease (in mother) | 2.7 | 3.2 | 4.5 | 1.8 | 2.1 | 1.6 | 2.1 | 2.1 | 2.0 | 1.7 | 1.6 | 0.1 |
Neuroticism score | 2.7 | 5.7 | 10.2 | -2.2 | -2.8 | -3.2 | -2.3 | -2.3 | -2.4 | -3.0 | -1.7 | -0.2 |
Number of live births | 2.7 | 3.8 | 7.7 | 2.2 | 1.3 | 2.0 | 1.6 | 1.7 | 1.5 | 2.0 | 2.1 | -2.8 |
Guilty feelings | 2.7 | 4.0 | 8.8 | -1.5 | -3.0 | -2.2 | -1.6 | -2.0 | -2.2 | -2.6 | -1.4 | -0.4 |
Deep venous thrombosis (DVT) (self-reported) | 2.7 | 3.5 | 8.4 | -2.9 | -1.8 | -1.8 | -1.5 | -2.0 | -2.2 | -1.2 | -1.8 | 1.0 |
Diabetes diagnosed by doctor | 2.6 | 4.2 | 6.0 | -1.9 | -1.8 | -2.2 | -2.3 | -2.2 | -1.9 | -2.3 | -2.4 | 1.0 |
Rheumatoid Arthritis | 2.5 | 3.5 | 12.2 | -1.5 | -3.5 | -1.3 | -1.5 | -2.1 | -2.2 | -1.0 | -1.7 | -0.5 |
Arm fat mass (right) | 2.5 | 10.1 | 19.8 | -3.2 | -2.2 | -4.5 | -3.8 | -3.5 | -3.5 | -2.9 | -3.0 | 0.5 |
Alzheimer’s Disease (in father) | 2.4 | 2.6 | 6.4 | 2.5 | 0.9 | 1.8 | 1.0 | 1.2 | 1.0 | 1.3 | 1.8 | -2.2 |
Lung FEV1/FVC ratio | 2.4 | 12.4 | 19.3 | -3.7 | -3.4 | -3.0 | -3.6 | -3.8 | -3.6 | -2.9 | -4.4 | 2.9 |
Neuroticism | 2.4 | 5.7 | 12.1 | -2.4 | -2.3 | -3.5 | -2.4 | -2.3 | -2.4 | -2.9 | -1.7 | 0.3 |
Medication: Metformin | 2.4 | 3.3 | 5.1 | -1.9 | -1.3 | -1.9 | -1.9 | -1.8 | -1.7 | -2.2 | -2.2 | 1.2 |
Frequency of tiredness / lethargy in last 2 weeks | 2.4 | 3.8 | 9.8 | -1.9 | -1.3 | -3.1 | -2.1 | -1.8 | -1.9 | -2.5 | -1.3 | -0.1 |
Shortness of breath walking on level ground | 2.4 | 2.8 | 5.7 | -1.0 | -2.0 | -2.2 | -1.5 | -1.5 | -1.8 | -1.5 | 0.1 | -2.4 |
Triglycerides | 2.3 | 3.8 | 6.3 | 1.9 | 2.5 | 2.0 | 1.9 | 2.1 | 2.1 | 2.3 | 1.5 | -0.1 |
Qualifications: College or University degree | 2.3 | 7.4 | 22.0 | -3.3 | -0.2 | -1.9 | -2.1 | -2.1 | -1.7 | -1.8 | -3.9 | 4.7 |
Depression (Nagel 2018) | 2.2 | 3.4 | 5.2 | -2.3 | -1.6 | -2.2 | -1.8 | -1.6 | -1.4 | -2.0 | -1.8 | 1.6 |
Eye problems/disorders: Diabetes related eye disease | 2.2 | 2.4 | 4.3 | -1.3 | -1.7 | -1.4 | -1.3 | -1.4 | -1.2 | -1.9 | -2.1 | 1.2 |
Relative age voice broke | 2.2 | 3.3 | 6.4 | 1.8 | 1.0 | 1.9 | 2.5 | 1.9 | 1.6 | 1.1 | 2.3 | -1.8 |
Blood clot in the leg (DVT) | 2.2 | 2.9 | 6.5 | -2.5 | -1.6 | -1.6 | -1.3 | -1.8 | -2.1 | -1.2 | -1.6 | 0.8 |
Medication: Aspirin | 2.1 | 2.8 | 7.2 | 1.5 | 2.7 | 1.1 | 1.3 | 1.9 | 2.0 | 1.3 | 1.7 | -0.6 |
Mother’s age at death | 2.1 | 2.6 | 5.0 | 1.1 | 2.2 | 1.5 | 1.9 | 1.8 | 1.8 | 1.6 | 1.2 | 0.7 |
Other serious medical condition/disability diagnosed by doctor | 2.0 | 2.5 | 9.5 | -0.4 | -2.4 | -1.6 | -1.0 | -1.2 | -1.4 | -0.3 | 0.4 | -3.1 |
Fed-up feelings | 2.0 | 3.6 | 8.0 | -1.6 | -1.5 | -2.4 | -2.2 | -1.9 | -1.9 | -2.8 | -1.3 | -0.4 |
Frequency of tenseness / restlessness in last 2 weeks | 2.0 | 3.1 | 7.5 | -0.4 | -2.0 | -2.7 | -1.9 | -1.6 | -1.6 | -2.2 | -0.6 | -1.5 |
Had menopause | 2.0 | 2.5 | 3.7 | -1.9 | -1.5 | -1.8 | -1.7 | -1.8 | -1.7 | -1.3 | -1.7 | 0.5 |
Commuting to job workplace: Public transport | 2.0 | 2.4 | 3.6 | -1.9 | -1.5 | -1.2 | -1.5 | -1.6 | -1.5 | -1.2 | -1.6 | 1.8 |
Headache pain in last month | 1.9 | 3.3 | 5.8 | -1.8 | -2.0 | -1.6 | -1.4 | -1.7 | -1.7 | -2.4 | -1.8 | 1.7 |
Tinnitus: Yes, now most or all of the time | 1.9 | 2.2 | 3.9 | -1.6 | -0.9 | -1.8 | -1.6 | -1.4 | -1.1 | -1.2 | -2.0 | 1.3 |
Chronotype (morning person) | 1.8 | 4.2 | 8.7 | -2.9 | -2.2 | -2.3 | -1.8 | -2.1 | -2.3 | -1.1 | -1.7 | 1.0 |
Exposure to tobacco smoke outside home | 1.8 | 2.4 | 4.8 | -0.7 | -2.2 | -1.8 | -1.7 | -1.7 | -1.5 | -1.8 | -1.3 | -0.2 |
Financial situation satisfaction | 1.8 | 2.2 | 6.2 | -0.8 | -2.5 | -1.2 | -1.5 | -1.6 | -1.7 | -1.4 | -0.8 | -0.8 |
Basal cell carcinoma (self-reported) | 1.8 | 2.1 | 4.3 | 1.7 | 1.8 | 0.7 | 1.1 | 1.5 | 1.6 | 2.1 | 1.4 | 0.1 |
Ulcerative Colitis (UC) | 1.7 | 3.2 | 4.4 | -2.1 | -1.6 | -1.6 | -1.9 | -2.1 | -2.1 | -1.5 | -2.0 | 0.6 |
Leg fat percentage (right) | 1.7 | 6.2 | 16.8 | 2.8 | 2.8 | 1.1 | 1.5 | 2.0 | 1.8 | 0.2 | 3.6 | -4.1 |
Wears glasses or contact lenses | 1.7 | 2.0 | 4.5 | -2.1 | -0.7 | -1.6 | -1.0 | -1.2 | -1.1 | -1.2 | -1.9 | 1.2 |
Medication: Blood pressure | 1.7 | 3.2 | 7.1 | -2.0 | -1.6 | -2.0 | -1.6 | -1.7 | -1.8 | -2.7 | -1.4 | 1.0 |
Average weekly beer plus cider intake | 1.7 | 2.5 | 8.1 | 2.0 | 0.1 | 1.5 | 1.1 | 1.0 | 0.8 | 1.3 | 1.9 | -2.8 |
Irritability | 1.7 | 2.9 | 6.8 | -1.8 | -1.4 | -1.8 | -1.2 | -1.4 | -1.3 | -2.6 | -2.0 | 1.3 |
Leg fat mass (left) | 1.7 | 6.5 | 13.4 | -2.5 | -1.3 | -3.7 | -3.0 | -2.7 | -2.7 | -3.0 | -2.1 | -0.1 |
Diabetes (father) | 1.6 | 2.0 | 4.1 | -1.3 | -0.9 | -1.2 | -2.0 | -1.8 | -1.6 | -1.1 | -1.7 | 0.4 |
Qualifications: None of the above | 1.6 | 3.4 | 11.3 | 1.9 | 0.3 | 1.7 | 1.4 | 1.3 | 1.0 | 1.0 | 2.7 | -3.4 |
Medication: Cholesterol lowering | 1.6 | 2.5 | 3.7 | 1.8 | 1.6 | 1.7 | 1.5 | 1.7 | 1.8 | 1.9 | 1.3 | -0.4 |
Seen doctor (GP) for nerves, anxiety, tension or depression | 1.6 | 2.5 | 4.9 | -1.5 | -1.2 | -2.2 | -1.9 | -1.6 | -1.4 | -1.8 | -1.5 | 0.6 |
Health satisfaction | 1.6 | 2.1 | 3.9 | -1.7 | -1.3 | -2.0 | -1.6 | -1.4 | -1.5 | -1.7 | -0.9 | -0.4 |
Illnesses of siblings: Diabetes | 1.6 | 2.0 | 4.4 | -0.8 | -0.7 | -2.1 | -1.6 | -1.5 | -1.5 | -1.5 | -0.6 | -1.6 |
Ever taken oral contraceptive pill | 1.6 | 1.8 | 2.5 | 1.6 | 1.4 | 1.1 | 1.6 | 1.5 | 1.4 | 1.0 | 1.4 | -1.0 |
Eye problems/disorders: Glaucoma | 1.6 | 1.9 | 3.0 | 1.2 | 1.4 | 1.7 | 1.3 | 1.7 | 1.7 | 1.1 | 1.2 | 0.6 |
Blood Platelet Count | 1.5 | 17.5 | 28.5 | -5.2 | -3.0 | -4.1 | -4.3 | -4.5 | -4.4 | -5.3 | -4.0 | 0.9 |
Hypothyroidism/myxoedema (self-reported) | 1.5 | 2.8 | 4.3 | -1.4 | -1.8 | -2.1 | -1.9 | -1.9 | -2.0 | -1.2 | -0.5 | -1.7 |
Number of children fathered | 1.5 | 1.7 | 2.9 | 0.8 | 1.6 | 1.1 | 1.5 | 1.6 | 1.7 | 1.2 | 0.4 | 1.3 |
Frequency of depressed mood in last 2 weeks | 1.4 | 2.0 | 4.2 | -1.0 | -1.7 | -2.0 | -1.5 | -1.3 | -1.3 | -1.8 | -1.1 | 0.2 |
Ever had hysterectomy (womb removed) | 1.4 | 1.6 | 2.5 | 1.6 | 0.9 | 1.2 | 1.4 | 1.3 | 1.3 | 1.2 | 1.2 | -1.2 |
Hair/balding pattern: Pattern 4 | 1.4 | 3.4 | 11.2 | 0.8 | 3.4 | 1.4 | 1.8 | 2.0 | 2.0 | 2.1 | 1.0 | 0.4 |
Back pain experienced in last month | 1.4 | 2.1 | 7.3 | 1.3 | -0.3 | 1.7 | 1.5 | 1.3 | 1.2 | 2.7 | 1.0 | -0.8 |
Supplements: Zinc | 1.3 | 1.4 | 2.2 | -1.5 | -0.5 | -1.0 | -1.4 | -1.3 | -1.2 | -0.6 | -1.4 | 1.3 |
Pulse rate | 1.3 | 2.2 | 8.7 | 1.7 | -1.1 | 0.6 | 0.5 | 0.5 | 0.2 | 1.3 | 2.1 | -3.0 |
Qualifications: A levels/AS levels or equivalent | 1.3 | 2.9 | 7.7 | -1.4 | -0.4 | -1.7 | -1.5 | -1.5 | -1.4 | -1.2 | -2.3 | 2.8 |
Medication: Lansoprazole | 1.3 | 1.5 | 4.6 | 0.9 | 0.1 | 0.9 | 1.3 | 1.0 | 0.8 | 0.8 | 1.7 | -2.1 |
Medication: Seretide 50 evohaler | 1.3 | 1.5 | 3.7 | -1.9 | -1.0 | -1.2 | -1.4 | -1.4 | -1.3 | -0.9 | -0.8 | 0.6 |
Medication: Aspirin | 1.3 | 1.7 | 4.1 | 1.2 | 2.0 | 0.7 | 0.9 | 1.5 | 1.6 | 1.0 | 1.5 | -0.6 |
Leg fat percentage (left) | 1.3 | 4.7 | 17.3 | 2.1 | 2.3 | 0.6 | 1.0 | 1.5 | 1.3 | -0.2 | 3.2 | -4.2 |
Neuroticism (Nagel 2018) | 1.2 | 2.8 | 5.6 | -1.7 | -1.7 | -2.4 | -1.4 | -1.4 | -1.5 | -2.3 | -1.2 | 0.6 |
Worry (Nagel 2018) | 1.2 | 2.5 | 5.2 | -2.1 | -1.4 | -2.3 | -1.2 | -1.2 | -1.3 | -1.6 | -1.3 | 1.3 |
Maternal smoking around birth | 1.2 | 1.7 | 5.6 | 0.1 | -2.4 | -1.1 | -0.9 | -1.0 | -1.1 | -1.0 | 0.1 | -2.1 |
Diverticular disease/diverticulitis (self-reported) | 1.2 | 1.5 | 7.1 | 0.7 | 0.1 | -0.3 | 0.8 | 0.8 | 0.4 | 0.2 | 2.0 | -2.7 |
Nervous feelings | 1.2 | 2.3 | 4.0 | -1.5 | -1.9 | -1.9 | -1.2 | -1.4 | -1.6 | -2.0 | -0.9 | -0.3 |
Worrier / anxious feelings | 1.2 | 2.2 | 4.2 | -1.8 | -1.7 | -2.0 | -1.2 | -1.3 | -1.2 | -1.5 | -1.4 | 0.9 |
Leg fat mass (right) | 1.2 | 4.5 | 10.3 | -1.9 | -0.8 | -3.2 | -2.6 | -2.2 | -2.3 | -2.5 | -1.7 | -0.2 |
Hearing aid user | 1.2 | 1.3 | 2.7 | 0.5 | 1.1 | 0.9 | 1.6 | 1.3 | 1.3 | 1.6 | 1.0 | 0.3 |
Unable to work because of sickness or disability | 1.2 | 1.6 | 9.5 | 1.4 | -0.6 | 0.0 | 0.4 | 0.2 | 0.0 | 0.6 | 1.3 | -3.1 |
Depressed Affect (Nagel 2018) | 1.1 | 2.2 | 4.3 | -1.7 | -1.3 | -2.0 | -1.6 | -1.4 | -1.4 | -2.1 | -1.0 | 0.1 |
Blood Red Count | 1.1 | 10.2 | 23.3 | 2.8 | 4.8 | 2.4 | 2.8 | 3.5 | 3.8 | 3.6 | 2.7 | 0.1 |
Hypothyroidism (self reported) | 1.1 | 2.4 | 5.2 | -0.8 | -1.8 | -1.6 | -1.6 | -1.7 | -1.9 | -0.9 | -0.2 | -2.3 |
Type 2 Diabetes (T2D) (2018) | 1.1 | 2.1 | 4.5 | -1.5 | -0.7 | -1.2 | -1.3 | -1.3 | -0.9 | -1.8 | -2.1 | 1.6 |
Medication: Atenolol | 1.1 | 1.3 | 2.1 | -1.4 | -0.7 | -1.1 | -1.0 | -1.1 | -1.2 | -1.3 | -1.4 | 1.0 |
Ever unenthusiastic/disinterested for a whole week | 1.1 | 1.3 | 3.5 | -0.8 | -1.4 | -1.9 | -1.2 | -1.2 | -1.2 | -0.5 | -0.6 | -1.0 |
Financial difficulties in last 2 years | 1.1 | 1.5 | 3.2 | -0.7 | -1.8 | -1.2 | -1.5 | -1.3 | -1.4 | -1.3 | -0.5 | -0.7 |
Medication: Ibuprofen (e.g. Nurofen) | 1.1 | 1.4 | 2.9 | 0.7 | 1.2 | 0.9 | 1.3 | 1.4 | 1.5 | 0.9 | 0.5 | 1.7 |
Tense / ‘highly strung’ | 1.1 | 1.8 | 4.2 | -1.2 | -1.9 | -2.0 | -1.3 | -1.2 | -1.3 | -1.4 | -0.8 | 0.1 |
Mouth/teeth dental problems: Bleeding gums | 1.1 | 1.4 | 4.3 | 2.1 | 0.9 | 0.2 | 0.7 | 1.0 | 0.9 | 0.4 | 1.7 | -1.6 |
High blood pressure (siblings) | 1.1 | 1.6 | 6.4 | -0.9 | -0.2 | -1.4 | -1.2 | -1.3 | -1.3 | -2.5 | -0.8 | 0.1 |
Seen a psychiatrist for nerves, anxiety, tension or depression | 1.1 | 1.4 | 2.0 | -0.6 | -1.4 | -1.3 | -1.4 | -1.2 | -1.1 | -1.2 | -1.4 | 0.7 |
Miserableness | 1.1 | 2.0 | 3.3 | -0.7 | -1.8 | -1.6 | -1.8 | -1.5 | -1.5 | -1.3 | -0.9 | -1.0 |
Medication: Bendroflumethiazide | 1.1 | 1.6 | 3.5 | -1.2 | -1.4 | -1.4 | -1.2 | -1.3 | -1.4 | -1.9 | -0.7 | 0.4 |
Commuting to job workplace: Cycle | 1.1 | 1.3 | 2.8 | -1.4 | -1.1 | -1.1 | -1.0 | -0.9 | -0.8 | -0.4 | -1.3 | 1.7 |
Blood Eosinophil Count | 1.0 | 7.6 | 16.1 | -2.2 | -1.9 | -3.2 | -4.0 | -3.2 | -2.9 | -2.7 | -2.8 | -0.3 |
Pack years adult smoking proportion | 1.0 | 1.5 | 2.5 | -0.9 | -1.5 | -1.6 | -1.5 | -1.4 | -1.4 | -0.6 | -1.0 | -0.5 |
Townsend deprivation index at recruitment | 1.0 | 1.4 | 6.6 | 0.6 | -1.9 | -0.3 | -0.2 | -0.6 | -0.9 | -0.7 | 0.8 | -2.6 |
Taking other prescription medications | 1.0 | 1.6 | 3.2 | -1.3 | -1.5 | -1.8 | -1.2 | -1.2 | -1.3 | -1.1 | -0.4 | -1.0 |
Chronic bronchitis/emphysema (father) | 1.0 | 1.1 | 2.7 | 1.6 | 0.0 | 1.2 | 0.3 | 0.5 | 0.6 | 1.4 | 0.9 | -1.5 |
Mouth/teeth dental problems | 1.0 | 1.5 | 2.6 | -1.6 | -0.8 | -1.0 | -1.0 | -1.2 | -1.2 | -1.3 | -1.5 | 1.3 |
Happiness | 1.0 | 1.2 | 2.3 | -1.0 | -0.4 | -1.4 | -1.2 | -0.9 | -0.7 | -1.5 | -1.2 | 1.1 |
Birth weight of first child | 1.0 | 1.9 | 4.3 | 1.8 | 0.1 | 1.0 | 1.5 | 1.4 | 1.2 | 2.1 | 1.6 | -0.6 |
Family relationship satisfaction | 1.0 | 1.2 | 1.8 | -1.4 | -0.4 | -1.3 | -1.3 | -1.2 | -1.1 | -1.2 | -1.1 | 0.5 |
Number of self-reported non-cancer illnesses | 1.0 | 1.7 | 6.5 | -0.1 | -1.6 | -1.5 | -1.1 | -0.9 | -1.2 | -0.6 | 0.4 | -2.6 |
Cholesterol lowering medication | 1.0 | 1.5 | 3.2 | 0.8 | 1.8 | 1.2 | 1.3 | 1.5 | 1.5 | 0.6 | 0.9 | 0.9 |
Bipolar Disorder (2011) | 0.9 | 0.9 | 3.8 | -0.6 | 1.7 | 0.3 | 0.3 | 0.4 | 0.5 | 0.7 | 0.2 | 1.9 |
BMI | 0.9 | 5.4 | 10.0 | -1.5 | -0.8 | -3.2 | -3.0 | -2.5 | -2.5 | -2.9 | -1.3 | -1.9 |
Number of treatments/medications taken | 0.9 | 1.6 | 3.8 | -0.2 | -1.5 | -1.8 | -1.2 | -1.0 | -1.1 | -0.9 | 0.2 | -2.0 |
Relative age of first facial hair | 0.9 | 1.9 | 4.0 | 1.6 | -0.2 | 1.5 | 1.7 | 1.1 | 0.8 | 0.8 | 1.9 | -2.0 |
Average weekly fortified wine intake | 0.9 | 1.1 | 1.8 | 1.0 | 1.2 | 1.0 | 1.1 | 1.2 | 1.2 | 1.3 | 0.5 | 0.5 |
Frequency of unenthusiasm / disinterest in last 2 weeks | 0.9 | 1.2 | 2.8 | -1.0 | -1.2 | -1.7 | -1.0 | -0.9 | -0.9 | -1.3 | -0.7 | 0.1 |
Multivitamins +/- minerals | 0.9 | 1.2 | 4.1 | -2.0 | -0.5 | -1.4 | -1.0 | -1.0 | -1.0 | -0.4 | -1.1 | 0.2 |
Medication: Levothyroxine sodium | 0.9 | 1.6 | 2.7 | -1.3 | -1.5 | -1.7 | -1.3 | -1.4 | -1.5 | -0.8 | -0.3 | -1.0 |
Allergy | 0.9 | 2.1 | 5.0 | 2.2 | 0.7 | 1.2 | 1.1 | 1.2 | 1.1 | 0.9 | 1.9 | -1.8 |
Medication: Ramipril | 0.9 | 1.2 | 4.6 | -0.9 | -0.5 | -0.6 | -0.6 | -0.5 | -0.2 | -1.1 | -1.6 | 2.1 |
Exposure to tobacco smoke at home | 0.9 | 1.0 | 1.7 | -0.7 | -1.3 | -1.1 | -1.3 | -1.0 | -1.0 | -0.9 | -0.3 | -0.9 |
Number of full sisters | 0.9 | 1.0 | 7.0 | 1.0 | 0.0 | -0.3 | -0.3 | -0.1 | -0.1 | -0.2 | 1.1 | -2.6 |
Handedness (chirality/laterality): Left-handed | 0.9 | 1.0 | 2.4 | 0.5 | 0.7 | 0.8 | 1.6 | 1.2 | 1.1 | 1.2 | 0.9 | 0.4 |
Mouth/teeth dental problems: Mouth ulcers | 0.9 | 1.4 | 2.8 | 1.7 | 0.8 | 0.9 | 1.1 | 1.5 | 1.6 | 0.4 | 1.4 | -0.1 |
Osteoarthritis (self-reported) | 0.9 | 1.2 | 2.8 | 1.4 | 0.7 | 0.6 | 0.8 | 1.1 | 1.0 | 0.2 | 1.7 | -1.4 |
Medication: Lisinopril | 0.9 | 1.1 | 3.2 | -0.8 | -0.8 | -1.4 | -1.1 | -1.0 | -1.1 | -1.8 | -0.6 | -0.4 |
Bipolar Disorder (2018) | 0.8 | 1.2 | 2.6 | -0.6 | 0.5 | -1.6 | -1.6 | -1.1 | -1.3 | -1.4 | -0.0 | -0.3 |
Irritable Bowel Disease (IBD) | 0.8 | 1.9 | 2.8 | -1.7 | -1.4 | -1.2 | -1.4 | -1.6 | -1.6 | -1.1 | -1.7 | 0.6 |
Sensitivity / hurt feelings | 0.8 | 1.4 | 5.6 | 0.8 | -0.5 | 0.2 | 1.2 | 0.9 | 0.5 | 0.7 | 1.6 | -2.4 |
Past tobacco smoking | 0.8 | 1.4 | 2.9 | -1.4 | 0.8 | -1.1 | -1.4 | -1.0 | -0.7 | -0.5 | -1.7 | 1.7 |
Hayfever/allergic rhinitis (self-reported) | 0.8 | 1.1 | 3.6 | -1.9 | -0.5 | -0.3 | -0.7 | -1.0 | -1.0 | -0.5 | -1.5 | 1.0 |
Noisy workplace | 0.8 | 0.9 | 4.6 | 1.1 | -0.5 | -0.0 | 0.4 | 0.2 | -0.1 | 0.6 | 1.4 | -2.1 |
Suffer from ‘nerves’ | 0.8 | 1.3 | 2.3 | -1.2 | -1.0 | -1.4 | -1.1 | -1.0 | -0.9 | -1.5 | -0.9 | 0.9 |
Average weekly red wine intake | 0.8 | 1.2 | 6.9 | -0.9 | 0.4 | -0.3 | -0.0 | -0.1 | 0.1 | 0.1 | -1.6 | 2.6 |
Age started oral contraceptive pill | 0.8 | 1.0 | 3.4 | -1.5 | -0.8 | -0.6 | -0.0 | -0.6 | -0.6 | -0.6 | -1.3 | 1.8 |
Neuroticism (2016) | 0.7 | 1.1 | 2.8 | -0.7 | -1.1 | -1.7 | -1.3 | -0.8 | -0.8 | -1.2 | -0.5 | -0.5 |
Diabetes (mother) | 0.7 | 0.9 | 3.0 | -0.8 | 0.2 | -1.7 | -1.4 | -0.9 | -0.8 | -0.1 | -0.8 | 0.0 |
Supplements: Glucosamine | 0.7 | 0.9 | 2.1 | 0.9 | 1.4 | 0.6 | 1.2 | 1.2 | 1.0 | 0.5 | 1.0 | -0.2 |
Body mass index (BMI) | 0.7 | 3.0 | 6.4 | -0.8 | -0.5 | -2.5 | -2.1 | -1.7 | -1.8 | -2.2 | -0.3 | -2.0 |
Emphysema/chronic bronchitis | 0.7 | 0.8 | 1.6 | 1.0 | 0.2 | 0.8 | 1.2 | 0.9 | 0.8 | 0.5 | 0.9 | -1.2 |
Overall health rating | 0.7 | 1.5 | 5.4 | -0.6 | -0.8 | -1.5 | -1.2 | -0.9 | -1.0 | -1.0 | 0.3 | -2.3 |
Qualifications: NVQ or HND or HNC or equivalent | 0.7 | 0.9 | 1.9 | 1.4 | 0.1 | 0.6 | 0.7 | 0.8 | 0.9 | 1.3 | 0.9 | -0.9 |
Smoking status: Previous | 0.7 | 1.1 | 2.5 | 1.2 | -0.3 | 1.0 | 1.4 | 1.1 | 0.8 | 0.5 | 1.6 | -0.9 |
Osteoporosis (self-reported) | 0.7 | 0.8 | 4.8 | 0.7 | -0.8 | -0.1 | -0.1 | -0.1 | -0.3 | 0.4 | 1.1 | -2.2 |
Medication: Gliclazide | 0.7 | 0.7 | 1.6 | -0.4 | -0.3 | -0.9 | -1.3 | -1.1 | -1.0 | -0.8 | -1.1 | 0.4 |
Pain experienced in last month | 0.7 | 1.1 | 2.6 | -1.3 | -0.1 | -0.5 | -0.8 | -0.9 | -0.9 | -1.2 | -1.4 | 1.6 |
Pack years of smoking | 0.7 | 1.0 | 2.0 | -0.9 | -1.1 | -1.4 | -1.3 | -1.1 | -1.1 | -0.2 | -0.9 | -0.3 |
Lupus | 0.6 | 0.9 | 5.5 | -0.8 | -0.3 | -0.2 | -0.1 | -0.3 | -0.3 | 0.2 | -1.4 | 2.3 |
Average weekly spirits intake | 0.6 | 0.8 | 2.1 | 1.0 | 0.4 | 0.3 | 0.7 | 0.7 | 0.5 | 0.8 | 1.2 | -1.4 |
Age when periods started (menarche) | 0.6 | 1.4 | 6.1 | -1.5 | -1.0 | 0.7 | 0.5 | -0.4 | -0.4 | -0.4 | -1.5 | 2.5 |
Tinnitus: Yes, but not now, but have in the past | 0.6 | 0.7 | 2.1 | 0.5 | 0.4 | 0.5 | 0.9 | 1.0 | 0.9 | 1.4 | 0.8 | -0.2 |
Illnesses of siblings | 0.6 | 0.9 | 2.6 | -0.1 | -0.0 | 1.4 | 0.8 | 0.7 | 0.7 | 1.6 | -0.3 | 1.2 |
Pulse wave reflection index | 0.6 | 0.7 | 2.2 | -1.5 | 0.3 | -0.7 | -0.7 | -0.7 | -0.8 | -0.8 | -1.0 | 0.4 |
Chronic bronchitis/emphysema (mother) | 0.6 | 0.7 | 1.5 | 0.6 | 0.3 | 1.0 | 1.2 | 1.1 | 1.1 | 0.4 | 0.8 | -0.2 |
Medication: Ibuprofen | 0.6 | 0.7 | 2.2 | 0.5 | 0.9 | 0.6 | 0.8 | 0.9 | 1.0 | 0.6 | 0.2 | 1.5 |
Reproduciblity of spirometry measurement using ERS/ATS criteria | 0.6 | 0.7 | 1.4 | 0.3 | 0.8 | 1.1 | 0.9 | 0.8 | 0.7 | 1.2 | 0.9 | -0.6 |
Pulse rate, automated reading | 0.6 | 2.0 | 9.3 | 1.1 | -1.5 | 0.0 | 0.3 | 0.2 | -0.0 | 1.1 | 1.9 | -3.0 |
Age at last live birth | 0.6 | 0.9 | 2.5 | -1.0 | -0.1 | -0.3 | -0.6 | -0.7 | -0.6 | -0.8 | -1.6 | 1.6 |
Illness, injury, bereavement, stress in last 2 years | 0.6 | 0.8 | 2.4 | 0.7 | 1.5 | 1.2 | 0.7 | 0.8 | 0.9 | 0.6 | 0.3 | -0.4 |
Loneliness, isolation | 0.6 | 0.8 | 2.7 | 0.3 | -1.0 | -1.1 | -0.8 | -0.4 | -0.7 | -0.7 | 0.6 | -1.6 |
Long-standing illness, disability or infirmity | 0.6 | 1.0 | 1.5 | -1.2 | -1.1 | -1.2 | -0.7 | -1.0 | -1.1 | -1.0 | -0.7 | -0.4 |
Eye problems/disorders: Cataract | 0.6 | 0.7 | 1.6 | -0.7 | -0.4 | -0.5 | -0.9 | -0.7 | -0.7 | -1.3 | -0.7 | 1.1 |
Number of operations (self-reported) | 0.6 | 0.9 | 4.1 | 0.8 | -0.1 | 0.1 | 0.7 | 0.6 | 0.4 | 0.0 | 1.6 | -2.0 |
Ever had prostate specific antigen (PSA) test | 0.6 | 0.7 | 4.2 | -0.6 | 0.2 | -0.5 | -0.4 | -0.2 | -0.0 | -0.6 | -0.7 | 2.0 |
Ever depressed for a whole week | 0.6 | 0.7 | 2.5 | 0.7 | 0.2 | 0.0 | 0.5 | 0.6 | 0.4 | 1.1 | 1.2 | -1.6 |
Medication: Omeprazole (e.g. Zanprol) | 0.6 | 0.7 | 1.5 | 0.7 | 1.1 | 0.7 | 0.7 | 1.0 | 1.2 | 0.7 | 0.8 | 0.0 |
Heart disease (siblings) | 0.6 | 0.8 | 2.9 | 0.3 | -0.9 | -1.4 | -0.6 | -0.5 | -0.6 | -0.5 | 0.2 | -1.7 |
Prostate Cancer | 0.5 | 0.7 | 1.6 | 0.9 | -0.4 | 1.0 | 1.0 | 0.7 | 0.7 | 0.1 | 0.9 | -1.3 |
Systolic Blood Pressure | 0.5 | 2.4 | 6.2 | -1.8 | -0.2 | -1.1 | -1.5 | -1.4 | -1.2 | -0.9 | -2.1 | 2.5 |
Medication: Co-codamol | 0.5 | 0.6 | 3.0 | 0.4 | -0.6 | -0.8 | -0.2 | 0.0 | -0.1 | -0.6 | 0.9 | -1.7 |
Heel bone mineral density (BMD) T-score, automated (left) | 0.5 | 1.1 | 4.6 | -1.0 | 2.1 | -1.0 | -1.2 | -0.5 | -0.2 | -0.9 | -0.8 | 0.6 |
Hayfever, allergic rhinitis or eczema | 0.5 | 1.1 | 5.8 | -0.6 | 1.0 | 0.5 | 0.5 | 0.6 | 0.9 | 0.5 | -1.0 | 2.4 |
Heel bone mineral density (BMD) T-score, automated (right) | 0.5 | 1.0 | 3.7 | -1.4 | 1.9 | -1.1 | -1.1 | -0.5 | -0.4 | -0.5 | -0.6 | 0.4 |
Hair/balding pattern: Pattern 3 | 0.5 | 0.7 | 2.5 | -0.8 | 1.0 | 0.2 | -0.2 | -0.2 | 0.1 | 0.4 | -1.3 | 1.6 |
Medication for cholesterol, blood pressure or diabetes | 0.5 | 0.9 | 2.3 | -1.5 | -0.7 | -0.9 | -0.7 | -0.8 | -1.0 | -0.9 | -0.8 | 0.9 |
Number of full brothers | 0.5 | 0.7 | 2.0 | -1.1 | -1.4 | -0.5 | -0.8 | -0.8 | -0.9 | -0.0 | -0.4 | -0.5 |
Angina (self-reported) | 0.5 | 0.6 | 1.8 | -1.3 | 0.1 | -1.1 | -0.6 | -0.5 | -0.5 | -1.2 | -0.6 | 0.2 |
Heart disease (mother) | 0.5 | 0.6 | 1.1 | 1.1 | 1.0 | 0.2 | 0.6 | 0.9 | 0.9 | 0.3 | 0.9 | -0.3 |
Commuting to job workplace: Car/motor vehicle | 0.5 | 0.5 | 2.7 | 0.8 | 0.5 | 0.3 | 0.2 | 0.5 | 0.4 | 0.6 | 0.6 | -1.6 |
Mineral and other dietary supplements | 0.5 | 0.7 | 1.3 | -0.5 | -0.8 | -0.3 | -1.1 | -1.1 | -1.0 | -0.8 | -1.0 | 0.3 |
Smoking status: Current | 0.5 | 0.7 | 2.7 | 0.1 | -1.6 | -0.3 | -0.4 | -0.6 | -0.7 | -0.0 | 0.3 | -1.6 |
Average weekly champagne plus white wine intake | 0.5 | 0.7 | 1.8 | -0.7 | -0.7 | -0.8 | -0.8 | -0.8 | -0.8 | -0.9 | -0.8 | 1.3 |
Supplements: Fish oil (including cod liver oil) | 0.5 | 0.6 | 1.3 | 0.4 | 1.1 | 0.7 | 0.9 | 1.0 | 0.9 | 0.4 | 0.7 | -0.0 |
Diastolic blood pressure, automated reading | 0.5 | 1.5 | 4.3 | 0.1 | -1.0 | -2.1 | -1.6 | -1.1 | -1.1 | -1.3 | 0.1 | -1.3 |
Vascular/heart problems diagnosed by doctor | 0.5 | 1.3 | 3.8 | -0.0 | 0.8 | 1.5 | 1.1 | 0.8 | 0.9 | 1.9 | -0.2 | 1.5 |
Bipolar Disorder or Schizophrenia | 0.4 | 1.1 | 2.4 | -0.9 | 0.5 | -1.3 | -1.5 | -1.2 | -1.3 | -1.0 | -0.4 | -0.5 |
Schizophrenia vs Biploar Disorder | 0.4 | 0.5 | 3.0 | 0.1 | -0.9 | 0.5 | 0.4 | 0.2 | -0.1 | 0.5 | 0.5 | -1.7 |
Major Depression (MDD) | 0.4 | 0.5 | 2.0 | -0.4 | -0.3 | -0.9 | -0.4 | -0.3 | -0.5 | -0.8 | 0.8 | -1.4 |
Body Mass Index (BMI) (2010) | 0.4 | 0.5 | 2.1 | 1.4 | 1.1 | 0.3 | 0.2 | 0.7 | 0.8 | 0.6 | 0.3 | 0.1 |
Waist Hip Ratio (WHR) | 0.4 | 1.8 | 9.4 | 1.0 | -1.1 | 0.7 | 0.9 | 0.6 | 0.4 | -0.4 | 1.7 | -3.1 |
Allergy or Eczema | 0.4 | 1.0 | 5.8 | -1.2 | 0.6 | -0.3 | -0.2 | -0.0 | 0.3 | -0.2 | -1.2 | 2.4 |
Severe depression (siblings) | 0.4 | 0.4 | 1.9 | -0.5 | -0.2 | -0.8 | -0.4 | -0.4 | -0.5 | -0.4 | -0.2 | -1.4 |
Current tobacco smoking | 0.4 | 0.7 | 2.8 | 0.2 | -1.6 | -0.3 | -0.5 | -0.5 | -0.7 | 0.1 | 0.4 | -1.7 |
Stomach or abdominal pain in last month | 0.4 | 0.5 | 2.7 | 0.6 | 0.4 | -0.1 | 0.0 | 0.2 | 0.2 | 0.2 | 1.0 | -1.6 |
Arm fat percentage (right) | 0.4 | 1.6 | 8.7 | 1.2 | 0.7 | -0.8 | -0.3 | 0.3 | 0.1 | -0.2 | 1.7 | -3.0 |
Prospective memory result | 0.4 | 0.4 | 1.7 | -0.1 | -0.4 | 0.5 | 0.6 | 0.2 | -0.0 | 1.3 | 0.7 | -1.0 |
Breastfed as a baby | 0.4 | 0.6 | 1.9 | -0.6 | -1.4 | -0.1 | -0.2 | -0.6 | -0.4 | -0.8 | -1.0 | 0.8 |
Loud music exposure frequency | 0.4 | 0.4 | 1.2 | 0.5 | -0.3 | 0.1 | 0.5 | 0.5 | 0.5 | 1.0 | 0.5 | -1.1 |
Age at first live birth | 0.4 | 0.7 | 3.5 | -0.2 | 0.9 | 0.3 | 0.5 | 0.3 | 0.4 | -0.2 | -1.0 | 1.9 |
Medication: Omeprazole | 0.4 | 0.4 | 1.0 | 0.3 | 0.9 | 0.5 | 0.7 | 0.8 | 1.0 | 0.4 | 0.7 | 0.1 |
Illnesses of father: Heart disease | 0.4 | 0.6 | 1.9 | 0.7 | 1.4 | -0.0 | 0.2 | 0.9 | 1.0 | 0.5 | 0.9 | 0.0 |
Arm fat percentage (left) | 0.4 | 1.7 | 9.6 | 1.1 | 0.4 | -1.0 | -0.5 | 0.0 | -0.2 | -0.5 | 1.6 | -3.1 |
Medication for cholesterol | 0.4 | 0.6 | 2.3 | 0.9 | 0.4 | 1.2 | 0.5 | 0.5 | 0.6 | 1.5 | 0.2 | -0.3 |
Illnesses of father: None of the above (group 1) | 0.4 | 0.5 | 1.6 | 0.3 | 0.2 | 1.1 | 1.2 | 0.7 | 0.6 | 0.7 | 0.2 | 0.4 |
Alcohol drinker status: Never | 0.4 | 0.5 | 1.3 | 1.0 | 0.1 | 0.4 | 0.4 | 0.4 | 0.4 | 1.0 | 0.5 | -1.1 |
Risk taking | 0.4 | 0.6 | 1.5 | -1.2 | -0.2 | -1.1 | -0.8 | -0.6 | -0.8 | -0.8 | -0.6 | 0.4 |
Age at First Birth | 0.3 | 0.5 | 1.1 | -0.1 | 0.9 | 0.7 | 1.1 | 0.8 | 0.8 | 0.5 | -0.2 | 0.5 |
Fasting Glucose | 0.3 | 0.4 | 1.8 | -0.3 | 0.9 | 0.2 | 0.4 | 0.4 | 0.5 | 0.4 | -0.1 | 1.3 |
Heel T-Score | 0.3 | 2.6 | 19.2 | -0.8 | 4.4 | -1.0 | -0.6 | 0.3 | 0.4 | -1.3 | 0.2 | 0.1 |
Smoking Status | 0.3 | 0.8 | 3.7 | 0.6 | -1.2 | 0.3 | 0.3 | 0.0 | -0.3 | 0.1 | 1.1 | -1.9 |
Ever used hormone-replacement therapy (HRT) | 0.3 | 0.3 | 1.6 | -0.0 | 0.6 | -0.5 | -0.0 | 0.2 | 0.2 | 0.2 | 0.9 | -1.3 |
Systolic blood pressure, automated reading | 0.3 | 0.8 | 3.0 | -1.2 | 1.2 | -0.5 | -0.5 | -0.3 | -0.2 | -0.1 | -0.7 | 1.7 |
Hair/balding pattern: Pattern 2 | 0.3 | 0.3 | 1.1 | 0.8 | -0.0 | -0.1 | 0.1 | 0.2 | 0.0 | -0.5 | 1.0 | -1.0 |
Lung cancer (father) | 0.3 | 0.4 | 2.2 | 0.0 | -0.3 | -0.0 | 0.5 | 0.0 | -0.2 | 1.5 | 0.4 | -0.7 |
Pulse wave Arterial Stiffness index | 0.3 | 0.4 | 0.9 | -1.0 | 0.0 | -1.0 | -0.6 | -0.5 | -0.5 | -0.1 | -0.6 | 0.3 |
Birth weight | 0.3 | 0.6 | 2.7 | -0.4 | -1.6 | -0.2 | 0.0 | -0.5 | -0.6 | 0.8 | -0.8 | 0.7 |
Body fat percentage | 0.3 | 1.3 | 6.7 | 1.0 | 0.9 | -0.7 | -0.1 | 0.4 | 0.3 | -0.1 | 1.6 | -2.6 |
Comparative body size at age 10 | 0.3 | 0.9 | 4.6 | 1.3 | 0.3 | -0.2 | -0.3 | 0.0 | -0.2 | -0.4 | 1.3 | -2.2 |
Worry too long after embarrassment | 0.3 | 0.5 | 1.2 | -0.5 | -0.9 | -1.1 | -0.5 | -0.4 | -0.6 | -1.1 | -0.5 | 0.4 |
Leg pain on walking | 0.3 | 0.3 | 1.5 | -0.1 | -1.2 | -0.7 | -0.4 | -0.4 | -0.5 | -0.6 | 0.2 | -0.3 |
Ever had bowel cancer screening | 0.3 | 0.3 | 1.0 | -0.7 | -0.2 | -1.0 | -0.6 | -0.5 | -0.6 | -0.6 | -0.3 | 0.1 |
Friendships satisfaction | 0.3 | 0.4 | 2.1 | 0.4 | 0.3 | -0.4 | -0.5 | -0.3 | -0.5 | -0.7 | 0.6 | -1.4 |
Pain type(s) experienced in last month: Hip pain | 0.3 | 0.4 | 1.1 | 0.8 | 0.6 | -0.6 | -0.4 | 0.1 | 0.1 | 0.3 | 0.7 | -1.0 |
Fractured/broken bones in last 5 years | 0.3 | 0.4 | 0.8 | 0.8 | 0.4 | 0.6 | 0.6 | 0.8 | 0.9 | 0.9 | 0.4 | 0.5 |
Supplements: Calcium | 0.3 | 0.3 | 0.8 | 0.1 | -0.8 | -0.9 | -0.5 | -0.5 | -0.6 | -0.2 | 0.1 | -0.8 |
Crohns Disease (2012) | 0.2 | 0.3 | 0.7 | -0.8 | -0.1 | -0.6 | -0.3 | -0.2 | -0.1 | -0.1 | -0.7 | 0.8 |
Primary Biliary Cirrhosis | 0.2 | 0.2 | 0.7 | -0.2 | -0.8 | -0.1 | -0.7 | -0.5 | -0.4 | 0.0 | -0.5 | 0.4 |
Angina | 0.2 | 0.3 | 1.1 | -1.0 | 0.3 | -0.8 | -0.2 | -0.2 | -0.1 | -0.8 | -0.3 | 0.1 |
Medication for hormone replacement therapy | 0.2 | 0.3 | 0.7 | 0.1 | 0.4 | 0.3 | 0.5 | 0.5 | 0.4 | 0.6 | 0.9 | -0.6 |
Vitamin and mineral supplements | 0.2 | 0.3 | 1.0 | 0.9 | 0.6 | 1.0 | 0.3 | 0.3 | 0.4 | -0.0 | 0.2 | 0.3 |
Trunk fat percentage | 0.2 | 0.7 | 2.9 | -0.1 | -0.1 | -1.7 | -1.0 | -0.5 | -0.6 | -0.4 | 0.2 | -1.4 |
Bilateral oophorectomy (both ovaries removed) | 0.2 | 0.3 | 1.2 | -0.3 | -0.5 | 0.2 | 0.0 | -0.2 | -0.5 | -0.3 | 0.7 | -1.1 |
High blood pressure | 0.2 | 0.7 | 1.7 | 0.4 | -0.7 | -0.9 | -0.6 | -0.5 | -0.6 | -1.3 | 0.4 | -1.3 |
High blood pressure (mother) | 0.2 | 0.3 | 0.6 | -0.8 | -0.1 | -0.5 | -0.6 | -0.6 | -0.6 | -0.5 | -0.7 | 0.3 |
Heart attack | 0.2 | 0.2 | 0.9 | 0.1 | -0.1 | -0.7 | -0.3 | -0.2 | -0.3 | -0.4 | 0.3 | -1.0 |
Father’s age at death | 0.2 | 0.3 | 0.8 | 0.3 | 0.7 | 0.6 | 0.6 | 0.5 | 0.5 | 0.4 | 0.1 | 0.9 |
Serious illness, injury or assault of a close relative in last 2 years | 0.2 | 0.2 | 1.1 | 0.1 | 0.4 | 0.2 | 0.6 | 0.4 | 0.5 | -0.2 | 0.1 | 1.0 |
Ever highly irritable/argumentative for 2 days | 0.2 | 0.3 | 1.3 | 0.2 | -1.1 | -0.7 | -0.2 | -0.3 | -0.3 | -0.4 | -0.3 | -0.5 |
Medication: Paracetamol | 0.2 | 0.3 | 1.1 | -0.0 | -0.3 | -0.6 | -0.5 | -0.4 | -0.4 | -1.0 | 0.1 | -0.4 |
Glaucoma (self-reported) | 0.2 | 0.2 | 0.9 | -0.0 | 0.5 | 0.6 | 0.2 | 0.4 | 0.5 | -0.1 | 0.1 | 0.9 |
Reason for reducing amount of alcohol drunk: Health precaution | 0.2 | 0.3 | 1.7 | -0.1 | 0.1 | -0.0 | 0.2 | -0.1 | -0.3 | 0.1 | 0.6 | -1.3 |
Eye problems/disorders: None of the above | 0.2 | 0.2 | 0.9 | -0.9 | -0.3 | -0.4 | -0.3 | -0.4 | -0.4 | 0.4 | -0.5 | 0.3 |
Medication for pain relief, constipation, heartburn | 0.2 | 0.3 | 0.8 | -0.6 | -0.6 | 0.0 | -0.5 | -0.8 | -0.9 | 0.1 | -0.8 | 0.0 |
Medication: Allopurinol | 0.2 | 0.2 | 0.7 | 0.9 | 0.3 | 0.4 | 0.3 | 0.4 | 0.4 | 0.3 | 0.3 | -0.8 |
Had major operations | 0.2 | 0.3 | 0.8 | 0.7 | -0.3 | 0.2 | 0.5 | 0.5 | 0.5 | 0.2 | 0.9 | -0.5 |
Hypertension (Self-reported) | 0.2 | 0.5 | 2.0 | 0.8 | -0.4 | -0.6 | -0.2 | -0.1 | -0.2 | -0.8 | 0.7 | -1.4 |
Ever had stillbirth, spontaneous miscarriage or termination | 0.2 | 0.2 | 0.6 | 0.3 | 0.8 | -0.0 | 0.1 | 0.3 | 0.3 | -0.5 | 0.5 | -0.8 |
Forced expiratory volume in 1-second (FEV1), predicted percentage | 0.2 | 0.4 | 0.8 | 0.9 | -0.9 | 0.3 | 0.6 | 0.6 | 0.4 | -0.4 | 0.8 | -0.5 |
Medication: Atorvastatin | 0.2 | 0.2 | 0.6 | 0.5 | 0.1 | 0.2 | 0.2 | 0.3 | 0.3 | 0.5 | 0.8 | -0.7 |
Illnesses of father: High blood pressure | 0.2 | 0.2 | 1.3 | -0.2 | -0.1 | -0.6 | -0.4 | -0.3 | -0.3 | -1.1 | -0.1 | 0.3 |
Ever smoked | 0.2 | 0.4 | 2.2 | -0.1 | -1.5 | -0.1 | 0.1 | -0.2 | -0.4 | -0.3 | 0.2 | -1.0 |
Heart attack/myocardial infarction (self-reported) | 0.2 | 0.2 | 0.9 | -0.0 | -0.4 | -0.7 | -0.3 | -0.4 | -0.5 | -0.4 | 0.1 | -0.9 |
Schizophrenia (2018) | 0.1 | 0.3 | 0.5 | -0.7 | 0.2 | -0.3 | -0.7 | -0.6 | -0.6 | -0.1 | -0.5 | -0.5 |
HbA1C | 0.1 | 0.1 | 0.4 | 0.3 | 0.4 | -0.0 | -0.0 | 0.1 | 0.2 | 0.1 | 0.6 | -0.7 |
Schizophrenia (2014) | 0.1 | 0.3 | 0.5 | -0.6 | 0.2 | -0.4 | -0.7 | -0.7 | -0.7 | -0.4 | -0.6 | -0.1 |
Blood White Count | 0.1 | 1.0 | 3.0 | 0.5 | 1.5 | -0.3 | 0.4 | 0.7 | 0.7 | 1.1 | 1.0 | -1.7 |
Cardiovascular Disease | 0.1 | 0.4 | 1.2 | 1.1 | 0.6 | -0.2 | -0.2 | 0.3 | 0.3 | -0.5 | 0.7 | -1.0 |
Hearing difficulty/problems: Yes | 0.1 | 0.2 | 0.7 | -0.4 | 0.3 | 0.1 | 0.8 | 0.5 | 0.6 | 0.3 | 0.1 | 0.5 |
Serious illness, injury or assault to yourself | 0.1 | 0.2 | 1.3 | 0.3 | -0.3 | -0.1 | 0.1 | 0.1 | 0.0 | -0.1 | 0.3 | -1.1 |
Hearing difficulty/problems with background noise | 0.1 | 0.2 | 0.9 | -0.7 | -0.1 | -0.3 | 0.4 | 0.2 | 0.1 | 0.0 | -0.1 | 1.0 |
Had other major operations | 0.1 | 0.1 | 0.2 | -0.4 | -0.1 | -0.5 | 0.2 | 0.0 | -0.1 | -0.4 | 0.2 | -0.3 |
Pain all over the body in last month | 0.1 | 0.1 | 0.5 | -0.2 | -0.3 | -0.7 | -0.2 | -0.2 | -0.2 | 0.2 | 0.0 | -0.5 |
Mouth/teeth dental problems: Dentures | 0.1 | 0.2 | 0.9 | -0.5 | -0.2 | 0.5 | 0.3 | 0.1 | 0.0 | 1.0 | -0.0 | 0.3 |
Depression (self-reported) | 0.1 | 0.1 | 0.6 | -0.0 | -0.8 | -0.1 | 0.2 | 0.2 | 0.1 | -0.1 | 0.2 | -0.3 |
Gout (self-reported) | 0.1 | 0.1 | 0.2 | 0.4 | 0.0 | 0.4 | 0.4 | 0.4 | 0.3 | 0.3 | 0.3 | -0.3 |
Medication: Amlodipine | 0.1 | 0.2 | 0.6 | 0.8 | -0.4 | 0.2 | 0.2 | 0.4 | 0.4 | 0.6 | 0.4 | -0.2 |
Pulse wave peak to peak time | 0.1 | 0.1 | 0.5 | 0.1 | -0.6 | 0.1 | -0.2 | -0.2 | -0.1 | -0.3 | -0.5 | 0.7 |
Mouth/teeth dental problems: Loose teeth | 0.1 | 0.2 | 0.8 | 0.0 | 0.9 | 0.1 | 0.2 | 0.2 | 0.1 | 0.6 | 0.2 | -0.4 |
Neck or shoulder pain in last month | 0.1 | 0.1 | 0.2 | -0.2 | 0.4 | -0.4 | -0.5 | -0.3 | -0.1 | 0.2 | -0.3 | 0.1 |
Medication: Blood pressure | 0.1 | 0.2 | 1.1 | 1.0 | 0.3 | 0.1 | 0.0 | 0.2 | 0.4 | -0.2 | 0.1 | -0.5 |
Alcohol intake frequency. | 0.1 | 0.3 | 0.6 | 0.2 | -0.4 | -0.8 | -0.4 | -0.4 | -0.4 | -0.7 | 0.0 | -0.8 |
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) | 0.1 | 0.1 | 0.3 | 0.0 | -0.0 | 0.6 | 0.2 | 0.2 | 0.3 | 0.4 | 0.4 | -0.3 |
Qualifications: nursing, teaching | 0.1 | 0.2 | 0.5 | -0.3 | 0.1 | -0.2 | -0.5 | -0.4 | -0.3 | -0.7 | -0.7 | 0.5 |
Medication: Laxatives (e.g. Dulcolax, Senokot) | 0.1 | 0.1 | 0.2 | -0.1 | -0.4 | -0.2 | -0.5 | -0.2 | -0.1 | -0.1 | -0.3 | 0.4 |
Crohns Disease (2017) | 0.0 | 0.1 | 0.1 | -0.1 | 0.1 | 0.3 | 0.3 | 0.2 | 0.3 | 0.4 | -0.2 | 0.0 |
Mean Putamen Volume | 0.0 | 0.1 | 0.2 | -0.4 | 0.4 | 0.2 | -0.0 | -0.1 | 0.0 | 0.2 | -0.1 | 0.2 |
Falls in the last year | 0.0 | 0.1 | 0.2 | 0.1 | -0.0 | -0.4 | -0.0 | -0.0 | -0.1 | -0.5 | 0.2 | -0.2 |
Supplements: Vitamin C | 0.0 | 0.1 | 0.2 | 0.2 | -0.3 | -0.2 | 0.0 | 0.1 | 0.2 | 0.4 | 0.1 | 0.2 |
Medication: Paracetamol | 0.0 | 0.1 | 0.3 | 0.0 | 0.1 | -0.4 | -0.5 | -0.2 | -0.2 | -0.4 | 0.1 | -0.1 |
Alcohol drinker status: Previous | 0.0 | 0.1 | 0.2 | -0.4 | 0.0 | 0.1 | 0.3 | -0.0 | -0.1 | 0.4 | 0.1 | 0.2 |