TWAS hub - SPTY2D1-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.135	0.042	9.2e-05	0.122	NA	0.090	NA	0.112	2.1e-09	NA	2.9e-07	NA	9.0e-09
2	GTEx	Colon Transverse	0.305	0.087	5.2e-04	-0.002	NA	0.007	NA	0.030	4.1e-01	NA	1.4e-01	NA	1.4e-02
3	GTEx	Liver	0.370	0.118	5.5e-03	0.013	NA	0.087	NA	0.053	1.4e-01	NA	2.1e-03	NA	1.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
LDL Cholesterol	8.6	13.6	26.8	-5.2	0.3	-3.8
Height	3.4	66.3	151.3	12.3	-0.2	6.9
Medication: Cholesterol lowering	3.4	5.3	10.5	-3.2	-0.0	-2.3
Sensitivity / hurt feelings	3.2	5.5	14.9	-3.9	0.1	-1.3
Commuting to job workplace: Walk	3.2	3.4	6.2	2.5	-1.6	1.2
Breast Cancer	2.9	7.1	19.3	4.4	-1.1	0.9
Pulse wave reflection index	2.7	3.4	6.9	-1.8	-0.2	-2.6
Coronary Artery Disease (CAD)	2.6	3.1	8.9	-3.0	0.7	0.1
Mean Putamen Volume	2.5	2.9	7.0	1.3	-0.1	2.6
Trunk predicted mass	2.5	14.1	32.8	5.7	-0.9	3.0
Standing height	2.5	24.9	50.8	7.1	0.1	4.9
Medication for cholesterol, blood pressure or diabetes	2.5	4.1	7.6	2.8	0.7	2.1
Trunk fat-free mass	2.4	13.7	31.9	5.7	-0.9	2.9
Alcohol drinker status: Never	2.4	2.9	6.5	-0.1	1.5	-2.5
Medication: Metformin	2.3	3.3	6.6	0.8	1.6	2.6
Sitting height	2.3	16.2	40.1	6.3	-0.6	2.9
Mouth/teeth dental problems: Dentures	2.3	3.9	10.3	-3.2	0.3	-1.2
Blood clot in the leg (DVT)	2.3	2.9	5.2	2.3	0.8	1.7
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.4	3.7	1.9	0.2	1.9
Medication: Gliclazide	2.1	2.4	6.7	0.6	-0.3	2.6
Maternal smoking around birth	2.0	2.9	6.9	1.0	0.9	2.6
Medication: Simvastatin	2.0	3.0	6.2	-2.5	0.1	-1.7
Mood swings	2.0	3.6	5.8	-2.4	0.3	-2.2
Deep venous thrombosis (DVT) (self-reported)	2.0	2.5	4.8	2.2	0.9	1.4
Hand grip strength (left)	1.9	5.1	9.4	3.1	0.1	2.4
Ever used hormone-replacement therapy (HRT)	1.9	2.4	4.8	-0.4	2.2	-1.5
Number of incorrect matches in round	1.9	3.2	5.3	1.4	1.5	2.3
Worry too long after embarrassment	1.9	3.1	5.0	-2.2	-0.4	-2.0
Comparative height size at age 10	1.9	10.3	21.5	4.6	-0.8	3.0
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	5.5	0.9	-0.7	2.4
High cholesterol (Self-reported)	1.9	3.4	9.0	-3.0	-0.3	-1.1
Ever had prostate specific antigen (PSA) test	1.9	2.2	5.8	-0.9	2.4	-0.1
Cardiovascular Disease	1.8	6.1	11.0	-3.3	-2.0	-1.8
Systolic blood pressure, automated reading	1.8	5.2	11.2	-2.1	-0.1	-3.4
Medication for hormone replacement therapy	1.8	2.1	3.0	-0.8	1.7	-1.6
Taking other prescription medications	1.8	2.9	4.1	-1.7	-1.3	-2.0
Pulse wave peak to peak time	1.8	2.1	3.1	1.8	0.1	1.8
Mouth/teeth dental problems: Loose teeth	1.8	2.1	5.0	2.2	-0.4	1.1
Whole body fat-free mass	1.8	10.4	26.1	5.1	-0.8	2.1
Whole body water mass	1.8	10.5	26.3	5.1	-0.8	2.2
Financial situation satisfaction	1.8	2.3	5.5	-2.3	0.6	-1.0
Fasting Glucose	1.7	2.1	5.8	-0.2	2.4	-0.6
Townsend deprivation index at recruitment	1.7	2.4	4.2	1.4	2.0	1.0
Exposure to tobacco smoke at home	1.7	1.9	3.6	1.4	-0.3	1.9
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	3.4	0.9	-1.0	1.8
Number of self-reported non-cancer illnesses	1.7	3.0	4.2	-1.9	-1.1	-2.0
Pain type(s) experienced in last month: Hip pain	1.7	2.2	5.2	0.4	1.1	2.3
Financial difficulties in last 2 years	1.6	2.2	5.2	-0.9	2.3	0.6
Neck or shoulder pain in last month	1.6	2.3	5.6	1.1	-0.4	2.4
Eye problems/disorders: Glaucoma	1.6	1.9	3.9	2.0	0.8	1.0
Alzheimer’s Disease (in father)	1.5	1.7	4.8	-0.3	-2.2	-0.4
Age at First Birth	1.5	2.2	2.5	-1.6	-1.4	-1.5
Vitamin and mineral supplements	1.5	2.0	3.5	-1.9	-1.6	-0.3
Medication: Atorvastatin	1.5	1.9	3.6	-1.9	-1.4	-0.4
Basal metabolic rate	1.5	8.4	22.0	4.7	-0.6	1.7
Arm fat-free mass (left)	1.5	7.8	18.9	4.3	-0.5	2.1
Diastolic blood pressure, automated reading	1.5	4.8	12.0	-1.4	-0.5	-3.5
Arm predicted mass (left)	1.5	7.9	19.5	4.4	-0.4	2.0
Hayfever, allergic rhinitis or eczema	1.4	3.0	8.3	-0.7	0.3	-2.9
Medication: Amlodipine	1.4	2.0	3.2	-1.2	1.2	-1.8
Heart disease (mother)	1.4	1.7	4.3	-0.4	2.1	0.8
Depressed Affect (Nagel 2018)	1.3	2.7	5.2	-1.5	-0.9	-2.3
Ovarian Cancer	1.3	1.7	3.4	-1.8	-0.3	-1.3
Triglycerides	1.3	2.0	4.8	-2.2	0.2	-1.1
Chronotype (morning person)	1.3	3.0	5.6	1.0	2.4	1.6
Leg fat-free mass (left)	1.3	6.7	18.2	4.3	-1.1	0.8
Asthma	1.3	2.5	3.3	-1.1	-1.7	-1.8
Glaucoma (self-reported)	1.3	1.5	2.9	1.1	1.7	0.8
Arm predicted mass (right)	1.3	6.8	16.9	4.1	0.0	1.9
Diabetes diagnosed by doctor	1.3	2.2	4.8	0.5	1.2	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	4.1	0.2	-0.7	2.0
Ever taken oral contraceptive pill	1.3	1.5	2.8	-1.7	-0.1	-1.3
Commuting to job workplace: Public transport	1.3	1.6	2.8	1.3	-1.7	-0.6
Neuroticism (2016)	1.2	1.7	2.9	-0.7	1.3	-1.7
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.3	1.8	0.0	0.9
Leg predicted mass (left)	1.2	6.5	18.0	4.2	-1.0	0.8
Falls in the last year	1.2	1.6	3.3	1.8	-0.3	1.2
Medication: Lansoprazole	1.2	1.3	2.5	-1.2	0.3	-1.6
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.5	-0.1	1.3	1.6
Arm fat-free mass (right)	1.2	6.4	16.6	4.1	0.0	1.6
Commuting to job workplace: Car/motor vehicle	1.2	1.4	4.2	-2.0	0.1	0.0
Leg fat-free mass (right)	1.2	6.2	16.5	4.1	-1.2	0.8
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.5	0.3	1.9	-1.1
Age started oral contraceptive pill	1.2	1.5	3.6	-1.9	-0.7	-0.6
Alzheimer’s Disease (in mother)	1.1	1.3	2.4	-1.2	-1.6	0.3
Waist Hip Ratio (WHR)	1.1	4.8	10.6	-3.2	0.7	-1.8
Respiratory disease	1.1	2.4	5.8	-0.9	-0.8	-2.4
Hand grip strength (right)	1.1	2.9	5.7	2.4	0.7	1.6
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	2.7	-1.0	-1.7	-1.2
Body fat percentage	1.1	4.4	9.2	-1.6	1.2	-3.0
Eye problems/disorders: None of the above	1.1	1.3	1.9	-1.4	-1.2	0.7
Migraine (self-reported)	1.1	1.3	2.6	-1.6	1.0	0.6
Family relationship satisfaction	1.1	1.3	3.8	0.3	1.9	0.2
Arm fat percentage (left)	1.1	4.5	11.3	-1.2	0.9	-3.4
Eye problems/disorders: Cataract	1.1	1.2	3.0	1.7	0.3	-0.8
Mineral and other dietary supplements	1.1	1.5	4.2	-0.5	-2.0	0.3
Leg predicted mass (right)	1.1	6.1	16.3	4.0	-1.2	0.8
Leg fat percentage (left)	1.1	3.9	7.4	-1.9	0.9	-2.7
Unable to work because of sickness or disability	1.1	1.5	2.2	-1.5	0.4	-1.4
Neuroticism (Nagel 2018)	1.0	2.3	3.9	-1.7	-0.0	-2.0
Severe depression (siblings)	1.0	1.1	2.2	-1.5	0.6	0.9
Trunk fat percentage	1.0	4.2	8.8	-1.4	1.3	-3.0
Fed-up feelings	1.0	1.7	4.7	-0.2	0.7	-2.2
Neuroticism score	1.0	2.0	4.0	-2.0	-0.2	-1.4
Had major operations	1.0	1.2	1.7	-1.3	-1.3	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.9	1.7	-0.8	-0.1
Back pain experienced in last month	1.0	1.4	2.3	0.9	1.1	1.5
Tinnitus: Yes, now most or all of the time	1.0	1.1	1.5	0.8	1.2	-1.1
Risk taking	1.0	1.5	2.9	1.3	0.3	1.7
Fractured/broken bones in last 5 years	1.0	1.3	2.5	1.0	-1.6	-0.7
Alzheimer’s Disease (including proxy)	0.9	1.3	2.4	-1.0	-1.6	-0.8
Number of treatments/medications taken	0.9	1.7	4.2	-0.8	0.2	-2.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	1.9	-0.5	1.4	-0.9
Had menopause	0.9	1.2	3.2	0.2	1.8	-0.5
Diabetes (self-reported)	0.9	1.4	2.1	-0.0	1.4	1.4
Prospective memory result	0.9	1.1	1.7	-1.3	0.9	-1.0
Pulse wave Arterial Stiffness index	0.9	1.0	1.8	-1.0	-0.4	-1.3
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.6	-1.3	0.8	-1.0
Qualifications: College or University degree	0.9	2.7	4.7	1.7	-2.2	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.0	-1.1	-0.3	-1.4
Leg pain on walking	0.9	1.1	2.8	0.5	0.5	-1.7
Asthma (self-reported)	0.9	1.9	2.7	-1.0	-1.4	-1.6
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	1.4	1.2	-1.2	-0.7
Heart disease (siblings)	0.9	1.1	3.1	-1.8	0.4	-0.1
Bipolar Disorder (2018)	0.8	1.3	2.0	0.8	-1.2	1.4
Neuroticism	0.8	1.9	3.0	-1.7	-0.8	-1.4
Average weekly spirits intake	0.8	0.9	2.5	1.6	0.5	-0.2
Multivitamins +/- minerals	0.8	1.0	1.7	0.3	1.3	-1.1
Qualifications: None of the above	0.8	1.6	4.2	0.6	2.0	0.5
Arm fat percentage (right)	0.8	3.1	8.5	-0.9	0.4	-2.9
Breastfed as a baby	0.8	1.0	1.9	0.9	-0.6	1.4
Leg fat percentage (right)	0.8	2.8	5.5	-1.4	0.9	-2.3
Medication: Blood pressure	0.8	1.3	2.1	-1.4	-0.5	-1.3
Illnesses of father: Heart disease	0.8	1.1	2.5	-0.9	0.0	-1.6
Medication for cholesterol	0.8	1.2	2.2	1.5	-0.4	1.1
Breast cancer (self-reported)	0.8	1.0	1.4	-1.2	-1.2	-0.4
Cholesterol lowering medication	0.8	1.1	1.8	-1.3	-1.0	-0.9
Pain experienced in last month	0.8	1.3	1.8	-1.3	-0.6	-1.3
Alcohol drinker status: Previous	0.8	0.9	2.3	-0.5	-0.5	1.5
Schizophrenia vs Biploar Disorder	0.7	0.9	2.0	-0.5	0.7	-1.4
Body Mass Index (BMI) (2010)	0.7	0.9	1.7	1.1	1.3	-0.1
Blood Red Count	0.7	7.1	10.8	-3.3	-0.4	-3.2
Type 2 Diabetes (T2D) (2018)	0.7	1.4	3.7	-0.0	1.9	0.7
Qualifications: CSEs or equivalent	0.7	1.0	2.7	0.3	0.2	1.7
Allergy	0.7	1.6	4.7	0.4	0.2	2.2
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.4	1.2	-0.7	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.3	-1.1	-1.1	-0.1
Age at first live birth	0.7	1.2	2.0	-1.4	-0.3	-1.2
Number of full sisters	0.7	0.8	1.2	0.3	-1.1	1.1
Medication: Bendroflumethiazide	0.7	1.0	2.3	0.5	-0.7	-1.5
Depression (Nagel 2018)	0.6	0.9	1.2	1.1	0.9	0.7
Worry (Nagel 2018)	0.6	1.3	2.5	-1.6	0.0	-1.2
Primary Biliary Cirrhosis	0.6	0.9	2.2	1.5	-0.1	0.8
Blood White Count	0.6	4.6	11.2	-1.3	-0.9	-3.3
Systolic Blood Pressure	0.6	2.8	4.7	-2.2	-0.6	-1.8
Lung FEV1/FVC ratio	0.6	3.0	5.9	1.5	-0.9	2.4
Ever had hysterectomy (womb removed)	0.6	0.7	1.5	-0.6	-0.5	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.8	-0.1	-1.2	1.7
Mouth/teeth dental problems	0.6	0.9	1.5	0.7	-1.2	-0.8
Weight	0.6	3.2	9.4	3.1	0.4	-0.0
Lung cancer (father)	0.6	0.7	1.7	0.1	1.3	-0.6
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.3	-0.6	0.8	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	0.8	-0.8	-0.9	0.8
Medication: Omeprazole	0.6	0.7	1.2	1.1	-0.9	-0.0
Smoking status: Current	0.6	0.9	2.1	0.7	-0.3	1.4
Miserableness	0.6	1.1	2.2	-0.6	-1.5	-0.8
Mother’s age at death	0.6	0.8	2.2	-1.5	-0.1	0.4
Commuting to job workplace: Cycle	0.6	0.8	1.8	1.4	-0.0	0.7
Vascular/heart problems diagnosed by doctor	0.6	1.7	3.1	1.8	1.1	0.9
Bipolar Disorder or Schizophrenia	0.5	1.3	1.9	-0.4	-1.4	1.4
Reaction Time	0.5	0.9	1.9	-0.7	0.6	1.4
Prostate Cancer	0.5	0.7	2.1	-0.2	-1.5	0.1
HDL Cholesterol	0.5	0.8	1.2	-1.1	-0.1	-1.1
Lupus	0.5	0.7	1.4	0.3	0.7	1.2
Smoking Status	0.5	1.3	1.6	0.8	-1.3	1.3
Supplements: Zinc	0.5	0.6	1.5	1.2	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	2.3	0.3	-1.5	1.1
High blood pressure (mother)	0.5	0.7	1.0	-0.2	-1.0	-1.0
Body mass index (BMI)	0.5	2.0	6.0	-0.3	0.2	-2.4
Impedance of leg (left)	0.5	2.6	4.9	-2.2	1.5	0.8
Hair/balding pattern: Pattern 2	0.5	0.7	1.2	1.1	0.1	-0.9
Forced vital capacity (FVC)	0.5	2.0	3.2	1.8	1.2	1.2
Worrier / anxious feelings	0.5	1.0	2.9	-1.7	0.2	-0.3
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.7	0.5	-0.5	-1.6
Depression (self-reported)	0.5	0.6	1.5	-1.2	0.5	-0.3
Illnesses of mother	0.5	0.6	1.7	1.3	-0.3	0.4
Loud music exposure frequency	0.5	0.6	1.3	-0.5	1.1	-0.4
Gout (self-reported)	0.5	0.6	1.0	-1.0	0.6	-0.7
Forced vital capacity (FVC), Best measure	0.5	1.7	2.5	1.0	1.3	1.6
Exposure to tobacco smoke outside home	0.5	0.7	1.5	0.5	0.5	1.2
Medication: Allopurinol	0.5	0.7	1.0	-0.5	0.9	-1.0
Medication: Seretide 50 evohaler	0.5	0.5	0.7	-0.9	-0.6	-0.7
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.5	0.2	-1.2	-0.6
Average weekly red wine intake	0.5	0.7	1.1	0.9	1.0	-0.3
Friendships satisfaction	0.5	0.7	1.0	1.0	0.9	-0.3
Osteoarthritis (self-reported)	0.5	0.7	1.7	-0.6	1.3	-0.1
Medication: Aspirin	0.5	0.6	1.3	0.0	1.2	-0.7
Schizophrenia (2018)	0.4	0.8	1.4	-1.2	-0.7	0.7
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.4	-0.5	-1.2	-1.1
Medication: Co-codamol	0.4	0.5	0.9	0.7	0.3	0.9
Impedance of leg (right)	0.4	1.9	2.2	-1.5	1.5	1.2
Age when periods started (menarche)	0.4	0.8	1.4	1.0	-0.5	1.2
Serious illness, injury or assault to yourself	0.4	0.5	1.2	1.1	-0.1	-0.5
High blood pressure	0.4	1.1	2.0	-1.4	-0.9	-0.7
Supplements: Glucosamine	0.4	0.5	1.5	-1.2	-0.2	0.0
Trunk fat mass	0.4	1.7	4.3	0.2	0.9	-2.1
Had other major operations	0.4	0.5	1.1	0.4	-0.6	1.0
Hip circumference	0.4	1.7	4.5	2.1	0.7	-0.0
Time employed in main current job	0.4	0.4	0.5	-0.7	-0.7	-0.6
Hair/balding pattern: Pattern 3	0.4	0.6	1.4	-1.2	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	1.8	1.0	1.0	1.4
Happiness	0.4	0.5	0.8	0.9	0.8	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.1	-1.0	0.4	-0.3
Tense / ‘highly strung’	0.4	0.7	1.1	-1.1	-0.3	-0.9
Birth weight of first child	0.4	0.7	1.7	-0.6	1.3	0.5
Birth weight	0.4	0.8	1.4	0.9	0.6	1.2
Whole body fat mass	0.4	1.6	3.6	0.4	1.0	-1.9
Supplements: Vitamin C	0.4	0.5	0.7	0.8	0.9	0.4
Knee pain experienced in last month	0.4	0.7	2.0	0.2	1.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.6	0.3	0.8	1.3
Handedness (chirality/laterality): Left-handed	0.4	0.4	1.2	0.2	-1.1	0.0
Loneliness, isolation	0.4	0.5	1.2	1.1	0.2	0.6
Long-standing illness, disability or infirmity	0.4	0.6	1.7	0.1	-1.3	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.0	0.1	0.9	1.0
Arm fat mass (left)	0.4	1.6	4.2	0.7	0.4	-2.0
Wears glasses or contact lenses	0.4	0.4	1.1	0.1	1.1	0.4
Hearing aid user	0.4	0.4	0.7	0.4	-0.6	-0.9
Medication: Lisinopril	0.4	0.5	0.8	-0.5	0.8	-0.9
Ever smoked	0.4	0.6	1.0	-0.9	-1.0	0.4
Average weekly beer plus cider intake	0.4	0.5	1.1	0.5	-1.0	0.5
Supplements: Calcium	0.4	0.4	1.2	1.1	-0.2	0.2
Basal cell carcinoma (self-reported)	0.4	0.4	0.8	0.9	0.3	0.6
Major Depression (MDD)	0.3	0.4	1.1	1.0	-0.2	0.2
Bipolar Disorder (2011)	0.3	0.3	0.6	0.1	-0.6	-0.8
Crohns Disease (2012)	0.3	0.5	0.8	0.9	0.7	-0.6
Heel T-Score	0.3	2.0	5.6	0.6	0.4	2.4
BMI	0.3	2.0	3.0	0.9	-1.5	-1.7
Allergy or Eczema	0.3	0.8	2.3	-0.2	0.2	-1.5
Lung FVC	0.3	1.7	3.2	-1.8	1.2	-0.8
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.7	0.9	0.3	0.6
Hearing difficulty/problems: Yes	0.3	0.4	0.9	0.7	0.9	-0.1
Relative age of first facial hair	0.3	0.5	0.8	0.9	-0.1	0.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	0.6	-0.8	-0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.0	-1.0	-0.3	0.2
Current tobacco smoking	0.3	0.5	1.1	0.5	-0.5	1.1
Relative age voice broke	0.3	0.4	0.7	0.9	0.1	0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.7	-0.1	-0.8	0.5
Medication: Atenolol	0.3	0.4	0.9	0.5	0.9	-0.1
Medication: Levothyroxine sodium	0.3	0.5	0.9	0.3	-0.7	-0.9
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	-0.1	1.0	-0.1
Past tobacco smoking	0.3	0.5	1.0	0.7	1.0	0.0
Illnesses of siblings	0.3	0.4	0.8	0.9	0.6	-0.4
Alcohol intake versus 10 years previously	0.3	0.5	1.3	0.2	0.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.2	0.2	1.1	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.4	0.7	0.6	1.6
Arm fat mass (right)	0.3	1.3	3.2	0.7	0.3	-1.8
Hair/balding pattern: Pattern 4	0.3	0.7	0.9	-0.9	0.7	0.9
Headache pain in last month	0.3	0.5	0.5	0.7	-0.7	-0.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.0	0.2	-0.9	-1.0
High blood pressure (siblings)	0.3	0.4	1.1	-1.0	-0.2	0.2
Number of children fathered	0.3	0.4	0.4	0.7	-0.5	0.6
Health satisfaction	0.3	0.4	1.2	1.1	-0.2	0.0
Shortness of breath walking on level ground	0.3	0.3	0.9	0.0	0.3	-0.9
Mean time to correctly identify matches	0.3	0.6	0.9	-0.3	1.0	1.0
Leg fat mass (right)	0.3	1.1	2.7	0.4	0.6	-1.6
Chest pain or discomfort	0.3	0.4	1.1	1.0	0.2	-0.4
Hypertension (Self-reported)	0.3	0.9	1.8	-1.3	-0.8	-0.5
Illnesses of siblings: Diabetes	0.3	0.4	1.1	0.1	-0.1	1.0
Qualifications: nursing, teaching	0.3	0.5	1.0	0.4	-1.0	-0.4
Osteoporosis (self-reported)	0.3	0.3	0.7	0.8	-0.1	0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	0.6	0.7	-0.3	0.8
Guilty feelings	0.3	0.5	1.0	0.6	0.4	-1.0
Illnesses of father: High blood pressure	0.3	0.4	0.7	-0.5	-0.6	-0.8
Number of operations (self-reported)	0.3	0.4	0.9	-0.2	-0.9	0.5
Impedance of whole body	0.3	1.7	3.6	-1.9	1.2	0.0
Leg fat mass (left)	0.3	1.1	3.1	0.2	0.5	-1.8
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.8	0.2	-1.4	-0.1
Crohns Disease (2017)	0.2	0.4	1.0	1.0	0.2	0.4
Ulcerative Colitis (UC)	0.2	0.3	0.5	-0.6	-0.7	0.1
Schizophrenia (2014)	0.2	0.4	0.6	-0.4	-0.6	0.8
Ulcerative Colitis	0.2	0.3	0.8	-0.9	-0.3	-0.0
Blood Eosinophil Count	0.2	1.7	4.5	2.1	-0.2	-0.8
Hypothyroidism (self reported)	0.2	0.5	1.1	0.1	-1.0	0.7
Diabetes (father)	0.2	0.3	0.9	0.9	0.1	0.2
Pack years adult smoking proportion	0.2	0.3	0.6	0.8	-0.5	0.3
Average weekly fortified wine intake	0.2	0.2	0.3	-0.5	0.5	0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.2	0.4	-0.3	0.4
Stomach or abdominal pain in last month	0.2	0.2	0.4	0.4	-0.7	0.0
Waist circumference	0.2	0.8	1.3	0.4	0.9	-1.1
Alcohol usually taken with meals	0.2	0.4	0.7	-0.8	0.6	-0.0
Nervous feelings	0.2	0.3	0.6	-0.5	0.8	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.5	-0.7	0.3	-0.5
Hearing difficulty/problems with background noise	0.2	0.4	0.7	0.5	0.8	0.5
Heart attack	0.2	0.3	0.8	-0.9	-0.2	0.1
Fluid intelligence score	0.2	0.5	0.8	0.9	-0.9	0.1
Father’s age at death	0.2	0.3	0.7	-0.2	-0.8	-0.3
Number of live births	0.2	0.3	0.6	0.4	0.3	-0.8
Noisy workplace	0.2	0.2	0.3	-0.4	0.3	-0.6
Impedance of arm (left)	0.2	1.1	1.5	-1.1	1.2	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.7	-0.2	-0.6	0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.8	0.1	0.0	0.9
Wheeze or whistling in the chest in last year	0.2	0.4	1.1	1.1	-0.1	-0.4
Emphysema/chronic bronchitis	0.2	0.2	0.4	0.0	-0.4	-0.7
Alcohol intake frequency.	0.2	0.4	1.3	-0.1	1.1	0.2
Overall health rating	0.2	0.4	0.6	0.8	0.0	0.7
Age at last live birth	0.2	0.4	0.7	0.4	-0.9	0.4
Medication: Aspirin	0.2	0.3	0.6	-0.1	0.4	-0.8
Smoking status: Previous	0.2	0.3	0.5	-0.5	-0.7	-0.5
Ever had bowel cancer screening	0.2	0.2	0.4	0.4	-0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	-0.1	0.7	-0.8
Medication: Blood pressure	0.2	0.4	0.7	-0.7	-0.0	-0.9
Ever depressed for a whole week	0.2	0.3	0.7	-0.9	-0.2	-0.3
Myopia	0.2	0.3	0.5	-0.2	-0.7	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.7	-0.9	-0.4	-0.0
Irritable Bowel Disease (IBD)	0.1	0.1	0.3	-0.2	-0.6	0.1
Rheumatoid Arthritis	0.1	0.1	0.3	0.4	-0.5	-0.1
Blood Platelet Count	0.1	1.2	3.4	-0.4	-0.4	-1.8
Hair Pigment	0.1	2.2	6.0	-0.3	0.7	-2.4
Angina	0.1	0.1	0.2	-0.4	-0.3	-0.0
Diabetes (mother)	0.1	0.2	0.2	0.3	0.4	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.5	0.7	0.3	-0.0
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.5	-0.1	-0.7	-0.2
Pain all over the body in last month	0.1	0.1	0.2	-0.1	-0.5	-0.1
Medication: Ramipril	0.1	0.2	0.5	-0.7	0.2	-0.2
Impedance of arm (right)	0.1	0.3	0.5	-0.7	0.5	0.3
Peak expiratory flow (PEF)	0.1	0.3	0.3	0.6	-0.5	-0.4
Comparative body size at age 10	0.1	0.3	0.7	0.1	0.8	-0.5
Medication: Ibuprofen	0.1	0.1	0.1	-0.4	0.3	-0.1
Pulse rate, automated reading	0.1	0.2	0.3	-0.4	0.3	-0.6
Suffer from ‘nerves’	0.1	0.1	0.2	-0.3	-0.4	-0.4
Average weekly champagne plus white wine intake	0.1	0.1	0.2	0.4	0.1	0.5
Medication: Paracetamol	0.1	0.1	0.1	0.3	0.3	-0.3
Irritability	0.1	0.2	0.3	-0.5	-0.3	0.3
Pack years of smoking	0.1	0.2	0.5	0.7	-0.3	0.3
HbA1C	0.0	0.0	0.1	0.3	0.2	0.0
Tanning	0.0	0.4	0.9	-0.4	0.1	1.0
Pulse rate	0.0	0.0	0.0	-0.1	0.0	0.0
Length of working week for main job	0.0	0.0	0.1	0.2	-0.1	-0.1
Medication: Paracetamol	0.0	0.1	0.2	0.1	0.1	-0.4
Number of full brothers	0.0	0.0	0.1	0.1	-0.2	-0.1
Medication for pain relief, constipation, heartburn	0.0	0.1	0.1	-0.3	-0.4	0.2
Angina (self-reported)	0.0	0.0	0.0	-0.1	-0.2	0.1

Hub : Genes

SPTY2D1-AS1

Models

Trait associations