Best TWAS P=1.99e-11 · Best GWAS P=1.2e-15 conditioned to 1.72e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | DCPS | 0.09 | 0.04 | lasso | 3 | 0.05 | 8.8e-05 | 4.52 | -5.6 | 1.8e-08 | -0.26 | 0.53 | 0.21 | FALSE |
| 2 | GTEx | Spleen | RP11-680F20.12 | 0.38 | 0.00 | lasso | 6 | 0.00 | 2.4e-01 | 0.96 | 5.1 | 2.8e-07 | 0.38 | 0.05 | 0.39 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DCPS | 0.08 | 0.03 | enet | 10 | 0.04 | 2.9e-09 | 4.52 | -5.6 | 2.0e-08 | -0.28 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ST3GAL4 | 0.08 | 0.04 | lasso | 4 | 0.05 | 3.5e-06 | 6.89 | 6.7 | 2.0e-11 | 0.51 | 0.20 | 0.66 | TRUE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | DCPS | 0.13 | 0.05 | blup | 80 | 0.08 | 3.8e-04 | 3.43 | -6.3 | 3.1e-10 | -0.51 | 0.05 | 0.13 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ST3GAL4 | 0.11 | 0.05 | enet | 13 | 0.07 | 2.9e-08 | 6.89 | 5.7 | 1.3e-08 | 0.54 | 0.04 | 0.95 | FALSE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | DCPS | 0.12 | 0.02 | blup | 80 | 0.05 | 2.2e-04 | 4.62 | -5.9 | 3.9e-09 | -0.40 | 0.68 | 0.05 | FALSE |
| 8 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DCPS | 0.26 | 0.07 | lasso | 6 | 0.12 | 4.5e-05 | 4.66 | -5.4 | 5.4e-08 | -0.30 | 0.18 | 0.27 | FALSE |