[Hub]/) : Traits : LDL Cholesterol :

chr11:125,134,725-126,914,307

Best TWAS P=1.99e-11 · Best GWAS P=1.2e-15 conditioned to 1.72e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts DCPS 0.09 0.04 lasso 3 0.05 8.8e-05 4.52 -5.6 1.8e-08 -0.26 0.53 0.21 FALSE
2 GTEx Spleen RP11-680F20.12 0.38 0.00 lasso 6 0.00 2.4e-01 0.96 5.1 2.8e-07 0.38 0.05 0.39 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma DCPS 0.08 0.03 enet 10 0.04 2.9e-09 4.52 -5.6 2.0e-08 -0.28 1.00 0.00 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma ST3GAL4 0.08 0.04 lasso 4 0.05 3.5e-06 6.89 6.7 2.0e-11 0.51 0.20 0.66 TRUE
5 The Cancer Genome Atlas Pancreatic Adenocarcinoma DCPS 0.13 0.05 blup 80 0.08 3.8e-04 3.43 -6.3 3.1e-10 -0.51 0.05 0.13 TRUE
6 The Cancer Genome Atlas Prostate Adenocarcinoma ST3GAL4 0.11 0.05 enet 13 0.07 2.9e-08 6.89 5.7 1.3e-08 0.54 0.04 0.95 FALSE
7 The Cancer Genome Atlas Stomach Adenocarcinoma DCPS 0.12 0.02 blup 80 0.05 2.2e-04 4.62 -5.9 3.9e-09 -0.40 0.68 0.05 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors DCPS 0.26 0.07 lasso 6 0.12 4.5e-05 4.66 -5.4 5.4e-08 -0.30 0.18 0.27 FALSE