Hub : Genes

DHODH

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1760 0.0490 2.6e-13 0.128 0.128 0.133 0.131 0.134 2.7e-15 2.4e-15 6.7e-16 1.1e-15 5.7e-16
2 GTEx Adipose Subcutaneous 0.2350 0.0570 5.7e-11 0.180 NA 0.198 NA 0.104 1.2e-14 NA 4.3e-16 NA 8.2e-09
3 GTEx Adipose Visceral Omentum 0.0830 0.0400 6.6e-03 0.009 NA 0.030 NA 0.012 9.9e-02 NA 1.0e-02 NA 7.7e-02
4 GTEx Artery Aorta 0.2130 0.0540 3.1e-09 0.153 NA 0.186 NA 0.177 9.1e-09 NA 1.7e-10 NA 5.1e-10
5 GTEx Artery Tibial 0.3437 0.0643 0.0e+00 0.300 NA 0.255 NA 0.312 7.6e-24 NA 4.9e-20 NA 5.9e-25
6 GTEx Brain Caudate basal ganglia 0.3710 0.1050 3.9e-04 0.054 NA 0.195 NA 0.113 1.2e-02 NA 2.8e-06 NA 4.0e-04
7 GTEx Brain Cerebellar Hemisphere 0.2070 0.0900 6.6e-03 0.174 NA 0.089 NA 0.146 3.1e-05 NA 2.8e-03 NA 1.4e-04
8 GTEx Brain Cerebellum 0.2220 0.0930 4.9e-03 0.020 NA -0.007 NA 0.008 8.5e-02 NA 5.9e-01 NA 1.8e-01
9 GTEx Brain Cortex 0.2090 0.0800 3.7e-03 0.057 NA 0.052 NA 0.035 1.1e-02 NA 1.5e-02 NA 3.9e-02
10 GTEx Brain Frontal Cortex BA9 0.3062 0.0973 1.4e-03 0.019 NA 0.062 NA -0.011 1.0e-01 NA 1.0e-02 NA 8.2e-01
11 GTEx Breast Mammary Tissue 0.0940 0.0420 5.1e-03 0.036 NA 0.039 NA 0.071 5.9e-03 NA 4.4e-03 NA 1.6e-04
12 GTEx Breast Mammary Tissue (Male) 0.0320 0.0646 3.5e-01 -0.002 NA -0.012 NA 0.033 3.7e-01 NA 8.2e-01 NA 5.9e-02
13 GTEx Breast Mammary Tissue (Female) 0.1252 0.0719 3.6e-02 0.044 NA 0.045 NA 0.075 1.9e-02 NA 1.8e-02 NA 2.9e-03
14 GTEx Cells Transformed fibroblasts 0.3340 0.0610 1.2e-14 0.247 NA 0.243 NA 0.252 1.6e-18 NA 3.1e-18 NA 5.8e-19
15 GTEx Colon Sigmoid 0.2410 0.0680 2.7e-06 0.255 NA 0.203 NA 0.209 1.6e-09 NA 1.1e-07 NA 6.5e-08
16 GTEx Colon Transverse 0.2230 0.0670 7.1e-05 0.059 NA 0.057 NA 0.085 9.1e-04 NA 1.1e-03 NA 7.6e-05
17 GTEx Esophagus Gastroesophageal Junction 0.1580 0.0590 6.5e-04 0.135 NA 0.088 NA 0.009 1.4e-05 NA 4.2e-04 NA 1.4e-01
18 GTEx Esophagus Mucosa 0.1450 0.0590 8.8e-04 0.086 NA 0.040 NA 0.075 2.4e-06 NA 1.1e-03 NA 9.6e-06
19 GTEx Esophagus Muscularis 0.2420 0.0580 5.7e-11 0.188 NA 0.246 NA 0.227 1.3e-11 NA 4.4e-15 NA 6.0e-14
20 GTEx Heart Left Ventricle 0.1631 0.0594 6.8e-05 0.129 NA 0.115 NA 0.124 2.4e-07 NA 1.1e-06 NA 3.9e-07
21 GTEx Lung 0.1448 0.0507 8.3e-05 0.102 NA 0.083 NA 0.055 3.2e-08 NA 6.5e-07 NA 4.5e-05
22 GTEx Muscle Skeletal 0.0830 0.0346 2.2e-03 0.035 NA 0.028 NA 0.027 2.0e-04 NA 8.0e-04 NA 1.1e-03
23 GTEx Nerve Tibial 0.3259 0.0740 2.6e-14 0.258 NA 0.248 NA 0.258 2.3e-18 NA 1.4e-17 NA 2.5e-18
24 GTEx Skin Not Sun Exposed Suprapubic 0.1980 0.0720 3.3e-04 0.159 NA 0.136 NA 0.133 4.7e-09 NA 7.1e-08 NA 9.6e-08
25 GTEx Skin Sun Exposed Lower leg 0.1310 0.0380 7.7e-07 0.137 NA 0.095 NA 0.039 2.0e-11 NA 2.7e-08 NA 3.5e-04
26 GTEx Testis 0.2950 0.0720 1.2e-07 0.244 NA 0.186 NA 0.206 3.3e-11 NA 1.2e-08 NA 1.6e-09
27 METSIM Adipose 0.0878 0.0289 3.1e-08 0.045 0.067 0.068 0.070 0.073 2.1e-07 2.4e-10 2.2e-10 1.2e-10 4.8e-11
28 TCGA Breast Invasive Carcinoma 0.0726 0.0276 3.8e-07 0.018 0.017 0.034 NA 0.014 1.0e-04 1.8e-04 1.3e-07 NA 4.5e-04
29 TCGA Head and Neck Squamous Cell Carcinoma 0.1362 0.0419 1.6e-12 0.113 0.125 0.122 NA 0.124 1.1e-12 7.7e-14 1.6e-13 NA 9.7e-14
30 TCGA Kidney Renal Clear Cell Carcinoma 0.1474 0.0434 1.1e-15 0.153 0.127 0.093 NA 0.140 6.4e-17 3.8e-14 1.2e-10 NA 1.5e-15
31 TCGA Kidney Renal Papillary Cell Carcinoma 0.0940 0.0520 6.9e-03 0.008 0.025 0.002 NA 0.008 1.1e-01 1.4e-02 2.4e-01 NA 1.0e-01
32 TCGA Brain Lower Grade Glioma 0.2683 0.0717 2.8e-16 0.136 0.148 0.165 NA 0.138 3.6e-15 1.7e-16 2.7e-18 NA 2.2e-15
33 TCGA Lung Adenocarcinoma 0.0959 0.0438 4.9e-04 0.004 0.027 0.018 NA 0.004 1.1e-01 3.4e-04 3.0e-03 NA 9.5e-02
34 TCGA Lung Squamous Cell Carcinoma 0.0671 0.0282 3.8e-05 0.053 0.043 0.038 NA 0.016 1.2e-06 9.8e-06 3.6e-05 NA 5.8e-03
35 TCGA Prostate Adenocarcinoma 0.1367 0.0449 1.2e-09 0.047 0.095 0.096 NA 0.063 1.0e-05 3.8e-10 3.4e-10 NA 3.7e-07
36 TCGA Soft Tissue Sarcoma 0.1460 0.0590 2.4e-05 0.122 0.069 0.121 NA 0.004 1.0e-07 6.5e-05 1.1e-07 NA 1.7e-01
37 TCGA Stomach Adenocarcinoma 0.0960 0.0470 1.6e-03 0.057 0.050 0.033 NA 0.043 6.2e-05 1.6e-04 1.8e-03 NA 4.4e-04
38 TCGA Testicular Germ Cell Tumors 0.1760 0.0730 4.7e-04 0.006 0.064 0.050 NA 0.011 1.9e-01 2.7e-03 7.2e-03 NA 1.2e-01
39 TCGA Thyroid Carcinoma 0.2170 0.0640 6.5e-12 0.147 0.071 0.146 NA 0.068 3.3e-14 1.8e-07 4.3e-14 NA 3.7e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39
Bipolar Disorder (2018) 1.4 2.3 5.3 -1.0 -1.8 -1.3 -1.1 0.9 0.4 1.5 0.8 -0.5 -0.4 -1.9 -1.2 -1.6 -1.7 -1.0 -2.2 -1.1 -1.3 -1.2 -1.8 -1.6 -1.6 -1.4 -0.8 -1.9 -1.5 -2.3 -2.2 -1.7 -1.4 -1.9 -2.1 -1.1 -1.1 -1.3 -1.9 -1.2 -2.2 -1.6
Bipolar Disorder or Schizophrenia 0.8 2.0 4.8 -1.2 -1.2 -0.9 -1.4 0.7 -2.1 1.4 -0.6 -1.7 -0.7 -2.0 -1.0 -1.9 -1.0 -1.0 -1.9 -1.1 -1.1 -1.8 -1.7 -1.3 -0.8 -1.4 -0.9 -1.5 -1.0 -2.1 -1.5 -2.0 -1.3 -2.0 -2.2 -0.7 -1.0 -0.6 -1.7 -0.8 -2.1 -1.5
Depressed Affect (Nagel 2018) 0.7 1.4 3.6 1.5 1.4 1.3 1.2 -1.7 -1.5 -1.5 0.7 1.0 0.1 -0.1 1.5 0.1 1.2 1.5 0.0 1.5 1.4 0.9 0.8 0.4 1.2 1.2 1.9 1.7 1.4 0.4 0.4 1.6 1.7 0.1 0.5 -0.1 1.5 1.1 0.3 1.4 0.9 1.2
Depression (Nagel 2018) 0.4 0.6 8.0 0.2 0.3 0.2 0.4 -0.5 -2.8 -0.4 1.0 0.1 -0.3 -0.9 0.4 -0.7 0.1 0.2 -1.1 0.3 0.3 -0.4 0.3 -0.3 1.1 0.1 1.1 0.7 0.7 0.2 1.1 1.1 0.6 0.1 0.2 0.5 1.2 1.1 -0.1 1.3 0.7 0.3
Intelligence (Savage-Jansen 2018) 1.6 4.9 17.0 -0.9 -2.7 -2.0 -1.3 1.0 0.8 1.5 -0.6 -1.8 -0.6 -1.3 -1.3 -1.1 -1.8 -0.9 -1.5 -0.9 -1.2 -0.9 -2.2 -1.1 -2.9 -1.0 -2.2 -2.7 -2.1 -2.7 -3.8 -4.0 -2.3 -3.3 -3.0 -2.8 -3.4 -3.2 -1.4 -3.1 -4.1 -1.8
Neuroticism (Nagel 2018) 0.8 1.8 3.7 1.5 1.8 1.1 0.8 -1.6 0.5 -1.8 -0.0 0.4 1.4 0.8 1.5 0.8 1.7 1.5 1.2 1.4 1.5 1.1 1.1 1.2 1.9 1.3 1.4 1.8 1.6 1.2 1.0 1.8 1.6 1.1 1.0 0.3 1.3 1.3 1.0 1.8 1.7 1.5
Schizophrenia (2018) 0.4 0.8 8.9 -0.7 -0.1 -0.2 -0.9 0.2 -3.0 0.5 -1.4 -1.8 -0.7 -1.0 -0.3 -1.1 0.2 -0.5 -0.6 -0.5 -0.4 -1.3 -0.7 -0.4 0.2 -0.6 -0.6 -0.4 -0.1 -0.8 -0.1 -1.1 -0.6 -1.0 -1.1 0.0 -0.4 0.3 -0.6 -0.0 -1.0 -0.6
Schizophrenia vs Biploar Disorder 1.0 1.3 4.0 0.9 1.7 0.2 0.4 -1.0 -1.0 -1.4 -1.6 -0.5 0.8 0.7 1.1 0.4 2.0 0.8 1.4 0.6 1.2 0.1 1.1 1.3 1.2 0.9 0.5 1.4 1.6 1.4 2.0 0.6 0.9 0.5 0.9 1.8 1.1 1.7 0.9 1.6 0.9 1.1
Worry (Nagel 2018) 0.3 0.6 3.8 -0.3 0.5 -0.6 -0.8 0.2 1.9 -0.3 -1.1 -1.2 0.9 0.4 -0.1 0.0 0.8 -0.4 1.0 -0.6 -0.1 -0.5 0.0 0.5 1.1 -0.1 -0.3 0.3 0.2 0.5 1.2 0.6 -0.0 1.0 0.1 0.1 -0.1 0.7 1.0 1.3 1.7 0.3
Alzheimer’s Disease (in mother) 2.7 3.2 6.8 2.0 1.8 1.5 2.0 -1.8 1.8 -1.9 0.7 0.3 2.1 2.5 2.0 2.4 1.8 2.2 2.6 2.2 1.9 2.2 1.8 2.6 1.8 2.1 0.8 1.8 1.8 2.1 1.2 0.8 1.7 1.5 1.9 1.1 0.9 1.0 2.0 0.6 0.7 1.8
Alzheimer’s Disease (in father) 0.1 0.1 0.4 -0.0 0.3 -0.6 0.0 -0.0 -0.3 -0.2 -0.5 -0.1 0.4 0.4 0.1 0.3 0.4 -0.0 0.6 -0.2 0.1 -0.1 -0.1 0.5 0.6 -0.0 -0.2 0.1 0.3 0.6 0.4 0.4 0.1 0.3 0.3 0.6 -0.1 0.5 -0.1 0.3 0.6 0.0
Alzheimer’s Disease (including proxy) 0.6 0.9 4.1 0.5 0.8 1.1 0.7 -0.4 1.1 -0.7 -0.4 -0.3 1.4 2.0 0.6 1.7 0.9 0.8 2.0 0.6 0.6 0.9 0.6 1.6 1.4 0.7 -0.3 0.7 0.7 1.6 0.6 0.3 0.4 1.0 1.1 1.0 -0.0 0.4 0.8 -0.2 0.5 0.7
Crohns Disease (2017) 1.0 2.1 6.0 -2.3 -0.9 -2.4 -2.1 2.4 -0.6 2.2 -1.3 -1.6 -1.3 -0.7 -2.1 -1.1 -1.4 -2.3 0.0 -2.0 -2.1 -1.6 -1.3 -1.0 0.7 -1.9 -1.3 -1.5 -1.7 -0.0 -0.4 -0.2 -1.6 0.6 -0.1 0.1 -0.6 -1.1 -1.4 -1.5 0.3 -1.6
Irritable Bowel Disease (IBD) 1.3 3.0 7.3 -2.6 -1.2 -2.2 -2.4 2.4 -1.4 2.3 -1.7 -2.0 -1.9 -1.8 -2.2 -2.1 -1.5 -2.7 -1.1 -2.5 -2.2 -2.4 -1.6 -1.7 -0.6 -2.3 -1.8 -1.8 -1.8 -1.0 -0.4 -0.6 -1.7 -0.0 -0.7 -0.5 -0.7 -0.8 -2.1 -0.7 -0.4 -1.9
Ulcerative Colitis (UC) 1.1 2.0 5.9 -1.6 -1.2 -1.5 -1.7 1.2 -1.1 1.4 -1.4 -1.6 -1.7 -2.4 -1.3 -2.4 -1.0 -1.9 -1.9 -1.8 -1.3 -2.0 -1.2 -1.7 -1.8 -1.6 -1.6 -1.4 -1.1 -1.4 -0.1 -0.6 -1.0 -0.4 -0.9 -0.7 -0.3 -0.1 -1.7 0.4 -0.7 -1.4
Major Depression (MDD) 0.3 0.3 2.9 0.2 -0.2 -0.4 0.3 -0.3 -0.5 0.1 1.7 -0.0 -0.2 -0.7 0.1 -0.4 -0.4 0.0 -1.3 0.3 0.2 -0.2 -0.1 -0.5 -0.4 -0.1 0.5 -0.1 -0.2 -0.7 -0.1 -0.5 -0.0 -1.3 -0.8 -0.6 -0.0 -0.2 -0.9 0.3 -1.4 -0.3
Reaction Time 1.5 2.8 10.1 -1.3 -1.9 0.7 -1.2 1.0 -0.3 1.4 -0.2 -0.7 -1.0 -1.3 -1.1 -1.1 -1.3 -1.2 -1.6 -1.3 -1.2 -1.2 -1.7 -1.9 -2.5 -1.3 -1.7 -1.8 -1.2 -2.2 -2.0 -2.6 -1.7 -2.6 -2.3 -1.7 -2.4 -1.5 -1.5 -2.1 -3.2 -1.7
Verbal and Numeric Reasoning (VNR) 1.0 2.5 11.1 -0.5 -1.8 -1.2 -1.1 0.8 0.1 0.8 -1.4 -1.0 -0.5 -0.7 -0.9 -0.8 -1.1 -0.3 -0.4 -0.5 -0.8 -0.4 -1.3 -0.6 -1.8 -0.5 -1.4 -1.9 -1.3 -1.6 -3.3 -3.0 -1.6 -1.9 -1.7 -1.7 -2.5 -2.6 -1.1 -2.9 -3.3 -1.0
Breast Cancer 1.3 3.1 9.0 1.7 1.4 -1.4 1.8 -1.7 -0.1 -1.6 1.6 2.1 2.2 1.6 1.7 1.7 1.7 1.7 1.5 1.9 1.7 1.9 1.8 1.9 2.4 2.1 3.0 1.5 1.7 1.7 0.9 1.6 1.9 2.2 2.2 0.2 1.3 1.3 2.6 0.4 1.7 2.0
Ovarian Cancer 0.3 0.4 1.4 0.7 0.2 -0.5 0.5 -0.4 0.1 -0.2 0.5 1.1 0.6 1.0 0.5 1.0 0.4 0.4 1.0 0.5 0.4 0.9 0.7 1.2 0.6 0.6 0.3 0.1 0.3 0.5 -0.5 -0.2 0.5 0.5 0.5 0.1 0.2 -0.2 0.6 -0.5 -0.8 0.7
Prostate Cancer 0.3 0.5 3.1 0.5 0.7 1.0 -0.1 -0.3 1.8 -0.3 -1.0 -0.2 0.9 0.8 0.5 0.5 0.5 0.4 1.3 0.1 0.4 0.5 0.6 1.0 0.2 0.4 -0.4 0.6 0.7 1.0 0.4 0.5 0.5 0.7 0.6 1.3 0.7 0.4 0.4 0.2 0.5 0.6
Age at First Birth 4.3 6.3 13.7 -2.5 -3.2 -2.4 -2.1 2.5 0.1 2.8 -0.0 -1.9 -1.4 -1.1 -2.6 -0.9 -2.6 -2.5 -1.7 -2.3 -2.5 -1.9 -2.7 -1.9 -2.3 -2.3 -2.1 -3.2 -2.8 -2.4 -2.8 -3.6 -3.1 -2.7 -2.8 -2.7 -3.7 -3.3 -1.9 -3.2 -3.3 -2.7
Bipolar Disorder (2011) 1.0 0.9 4.1 -0.7 -1.4 -0.0 -0.6 1.3 -0.4 1.1 0.6 0.7 -0.7 -0.3 -1.2 -0.2 -1.4 -0.5 -1.1 -0.4 -1.0 -0.3 -0.7 -0.9 -0.6 -1.0 -0.9 -1.1 -1.3 -0.8 -1.7 -0.7 -0.9 -0.9 -0.7 0.1 -0.3 -1.5 -1.2 -2.0 -1.4 -0.9
Body Mass Index (BMI) (2010) 4.2 5.8 10.1 2.6 2.8 2.2 3.0 -2.4 0.7 -2.4 2.7 3.2 2.4 2.2 2.5 2.4 2.1 2.5 1.6 2.8 2.5 2.5 2.5 2.2 2.2 2.5 2.7 2.8 2.4 2.6 2.3 2.9 2.8 1.9 2.7 1.4 2.8 2.3 1.5 2.1 1.7 2.3
Coronary Artery Disease (CAD) 3.0 3.6 11.8 2.5 1.4 2.2 2.7 -1.8 0.9 -2.3 3.0 2.5 2.3 2.1 1.8 2.7 1.4 2.8 1.4 2.6 1.8 2.4 1.5 2.1 1.7 2.1 3.4 1.7 1.5 1.8 0.5 0.8 1.6 1.1 1.7 -0.1 0.3 0.9 1.5 0.5 0.4 1.7
Crohns Disease (2012) 0.7 1.2 4.2 -1.6 -0.7 -2.0 -1.2 1.9 -0.5 1.5 0.5 -0.6 -1.2 -0.1 -1.7 -0.2 -1.3 -1.5 -0.0 -1.3 -1.7 -0.9 -1.0 -0.9 0.8 -1.5 -0.6 -1.1 -1.4 -0.0 -0.5 0.2 -1.2 0.3 -0.0 -0.6 -0.6 -1.2 -1.0 -1.2 0.1 -1.3
Mean Putamen Volume 1.1 1.3 3.1 1.0 1.1 1.8 0.9 -1.1 0.8 -1.0 0.2 1.0 0.6 1.5 1.3 1.4 1.0 0.9 1.6 1.0 0.9 1.3 1.4 1.3 0.9 1.4 0.4 1.2 1.2 1.3 0.7 1.1 1.2 1.4 1.4 0.8 0.8 0.9 1.3 0.5 0.9 1.4
Fasting Glucose 0.6 0.7 4.4 -0.6 -1.1 0.2 -1.2 1.1 0.5 0.3 -2.1 -0.9 0.2 -0.1 -0.9 -0.3 -0.5 -0.3 -0.1 -0.8 -0.8 -0.6 -0.4 -0.3 -0.6 -0.8 -1.1 -0.9 -0.8 -0.2 -1.0 -1.2 -1.1 -0.6 -0.7 1.3 -0.7 -1.0 -0.2 -1.2 -0.5 -0.6
HbA1C 0.2 0.3 3.1 0.5 -0.1 0.3 0.0 0.3 1.8 -0.6 0.2 0.9 0.5 -0.2 -0.3 -0.1 -0.1 0.7 -0.1 0.1 -0.2 0.1 -0.4 -0.3 -0.2 -0.2 0.3 -0.1 -0.4 -0.3 -1.3 -0.2 -0.3 -0.5 -0.4 0.4 -0.3 -1.0 -0.4 -0.6 -0.1 -0.2
HDL Cholesterol 0.9 1.4 2.9 1.4 1.7 -0.4 1.2 -1.7 0.8 -1.4 0.2 1.1 1.4 1.0 1.7 0.9 1.7 1.3 1.4 1.2 1.7 1.0 1.3 1.3 0.7 1.6 1.5 1.2 1.5 0.7 0.8 0.4 1.3 0.5 0.8 0.2 0.9 1.6 1.2 1.1 0.4 1.3
LDL Cholesterol 6.2 9.8 32.3 4.5 2.0 3.4 4.7 -4.8 -0.4 -3.7 2.0 5.7 1.4 1.1 4.5 1.9 3.2 4.7 0.3 4.3 4.4 3.8 3.6 1.6 -0.7 4.3 3.3 3.4 3.9 1.6 1.0 1.4 3.7 -0.4 2.1 3.4 2.8 3.2 1.7 1.2 -0.3 3.4
Lupus 0.2 0.2 1.0 0.2 -0.2 -0.4 0.6 -0.2 -0.5 0.2 0.2 0.2 -0.9 -0.3 0.2 -0.1 0.1 -0.1 -0.9 0.2 0.3 0.2 0.6 -0.2 -0.1 0.3 -0.0 0.1 0.1 0.3 0.6 1.0 0.5 0.8 0.9 0.5 0.7 0.3 0.4 0.4 1.0 0.2
Neuroticism (2016) 2.7 3.9 5.9 2.4 2.2 2.4 2.2 -2.1 1.0 -2.4 1.7 1.7 1.6 1.9 2.1 2.0 1.9 2.3 1.6 2.4 2.2 2.2 2.0 1.8 1.9 2.2 1.5 2.3 1.9 1.9 1.4 2.2 2.4 1.8 2.2 0.6 1.9 1.5 1.9 1.6 1.6 2.2
Primary Biliary Cirrhosis 0.2 0.2 2.0 0.3 0.1 -0.3 0.5 0.2 -1.2 -0.1 1.4 0.8 -1.0 0.8 -0.1 0.9 -0.1 -0.0 0.4 0.3 -0.0 0.5 0.3 0.3 0.5 0.1 -0.0 -0.0 -0.2 0.3 -0.1 0.2 0.0 0.2 0.3 -0.5 -0.0 -0.5 0.3 -0.1 -0.5 0.1
Rheumatoid Arthritis 0.6 0.9 2.6 -1.0 -0.4 -0.8 -1.2 0.7 0.6 0.8 -1.4 -1.0 -0.2 -1.0 -0.8 -1.1 -0.1 -1.0 -0.6 -1.1 -0.8 -1.3 -1.0 -1.0 -1.3 -1.0 -0.9 -0.8 -0.3 -0.9 -0.2 -1.5 -1.2 -1.6 -1.6 0.0 -1.1 -0.1 -0.9 -0.4 -1.0 -0.8
Schizophrenia (2014) 0.2 0.4 4.7 -0.3 0.5 -0.0 -0.6 -0.1 -2.2 0.2 -1.2 -1.3 0.4 -0.8 0.1 -1.0 0.9 -0.2 -0.1 -0.3 0.0 -1.0 -0.3 0.2 0.6 -0.3 -0.3 0.0 0.5 -0.3 0.5 -0.5 -0.1 -0.6 -0.7 0.9 0.5 1.0 -0.1 0.7 -0.4 -0.1
Triglycerides 1.7 2.8 9.8 2.4 1.0 2.8 2.5 -1.9 0.4 -2.0 2.0 3.1 1.4 1.4 1.8 1.7 1.1 2.6 0.5 2.5 1.8 2.4 1.6 1.4 0.8 1.8 1.7 1.8 1.5 1.1 0.0 1.3 1.8 0.1 1.3 1.8 1.6 0.6 0.8 0.4 0.1 1.6
Type 2 Diabetes (T2D) (2012) 0.5 0.6 2.7 0.6 0.6 0.4 0.9 -0.6 1.4 -0.5 1.4 0.6 1.6 1.2 0.6 1.4 0.8 0.7 0.9 0.8 0.8 0.8 0.6 1.2 0.9 0.8 0.4 0.3 0.6 0.7 0.2 -0.2 0.3 0.2 0.3 0.0 -0.3 0.4 0.7 0.2 0.1 0.6
Ulcerative Colitis 1.5 2.2 4.6 -1.6 -1.6 -0.8 -1.7 1.4 -1.3 1.5 -0.7 -1.4 -1.6 -2.1 -1.4 -2.1 -1.4 -1.8 -2.1 -1.9 -1.5 -2.0 -1.3 -1.8 -1.7 -1.7 -2.1 -1.6 -1.4 -1.7 -0.3 -1.3 -1.5 -0.9 -1.3 -0.7 -0.9 -0.7 -1.3 -0.2 -1.4 -1.5
Blood Eosinophil Count 0.2 1.3 6.8 1.1 0.9 1.5 1.4 -1.0 -0.7 -0.9 1.8 0.9 0.7 0.8 1.1 1.0 0.9 1.1 0.4 1.1 1.1 0.9 1.5 1.0 0.5 0.9 1.1 1.0 1.1 1.2 1.9 0.3 0.7 0.3 1.1 2.6 0.9 1.2 1.0 1.1 -0.5 1.0
Blood Platelet Count 0.1 1.2 11.3 -1.2 -0.6 1.1 -1.3 1.5 -1.4 0.5 -0.4 -3.4 -1.2 -0.5 -1.3 -0.7 -0.7 -1.2 -0.6 -1.0 -1.3 -1.3 -1.0 -0.3 1.1 -1.3 -1.1 -0.6 -1.0 -0.4 -0.2 -0.1 -1.2 0.1 -0.7 -1.0 -1.1 -1.1 -1.5 0.5 0.4 -1.1
Blood Red Count 1.2 11.6 34.9 4.1 2.3 4.1 3.4 -4.5 4.0 -3.6 -0.8 3.6 3.8 1.2 4.5 1.4 4.7 4.7 1.3 3.1 4.6 3.2 4.0 1.9 -1.8 4.1 3.0 3.1 4.5 2.2 2.9 1.3 3.3 0.9 2.0 5.9 2.9 4.9 4.1 2.4 1.3 4.0
Blood White Count 1.6 12.1 19.8 3.5 4.2 1.4 3.0 -3.0 2.6 -3.5 1.2 2.2 4.0 3.6 3.3 3.4 3.8 3.3 4.2 3.2 3.3 3.4 3.9 4.3 3.5 3.3 2.8 3.8 3.7 4.5 3.6 3.6 3.6 3.9 4.2 4.1 3.7 3.1 3.5 2.9 3.2 3.7
Heel T-Score 0.3 2.7 22.3 0.4 1.2 0.0 -0.6 -0.4 1.8 -0.9 -4.1 -1.4 1.6 0.6 0.7 -0.1 2.0 0.8 1.9 -0.4 0.7 -0.1 1.4 1.1 0.7 0.3 1.1 0.9 1.5 1.8 2.5 0.9 0.5 1.8 1.1 4.7 1.6 2.6 1.4 2.1 2.5 1.5
BMI 2.1 12.1 26.2 4.5 4.0 5.1 4.8 -4.7 -1.4 -3.3 4.7 4.3 2.8 1.6 4.4 2.3 3.3 4.6 1.2 4.9 4.3 4.0 3.4 2.2 1.0 3.9 4.1 3.9 4.1 2.1 2.7 3.0 4.2 0.4 2.4 2.0 4.2 2.9 3.0 3.1 0.4 3.3
Height 0.2 4.4 28.7 -0.8 2.2 -0.4 -0.8 1.1 -5.4 -0.5 -2.8 1.3 -3.9 1.0 -0.6 0.3 0.4 -1.1 1.7 -0.5 -0.7 -0.7 1.0 0.5 4.5 -0.7 0.2 1.9 -0.1 2.0 2.8 4.0 1.3 2.4 2.1 1.1 3.7 1.4 0.7 2.1 4.1 1.0
Waist Hip Ratio (WHR) 0.4 1.9 4.9 1.2 2.1 1.5 1.0 -1.3 1.2 -1.7 0.4 0.7 1.7 0.9 1.4 0.8 1.9 1.2 1.6 1.1 1.4 0.6 1.0 1.4 2.0 1.2 1.7 1.7 1.5 1.2 1.4 1.5 1.3 1.0 1.0 0.9 1.2 1.7 0.3 2.2 1.7 1.2
Systolic Blood Pressure 0.8 3.9 15.6 -1.5 -1.9 -2.9 -1.8 2.0 3.9 2.0 -1.7 -1.3 -0.6 1.0 -1.9 0.6 -1.6 -1.5 1.0 -1.8 -1.9 -0.3 -1.5 -0.6 -1.7 -1.2 -2.8 -2.5 -2.0 -0.9 -3.2 -2.5 -2.0 -0.7 -1.2 -1.5 -2.9 -2.9 -0.7 -4.0 -1.9 -1.3
Smoking Status 1.4 3.3 10.0 2.5 1.8 2.9 2.9 -2.5 -2.5 -1.9 3.2 2.6 0.5 0.6 2.2 1.3 1.1 2.2 0.2 2.7 2.2 2.2 1.5 0.7 0.4 2.1 2.1 1.9 1.6 0.3 0.7 1.5 2.3 -0.3 0.8 -1.3 1.8 0.9 1.3 1.5 -0.1 1.5
Allergy or Eczema 0.1 0.4 1.8 0.2 -0.3 0.2 0.1 -0.2 1.1 0.0 -1.2 -1.3 -0.3 -0.1 0.2 -0.1 -0.1 0.2 -0.0 0.0 0.2 0.0 -0.4 0.2 -1.3 0.1 -0.9 -0.3 -0.0 -0.3 -0.5 -1.3 -0.5 -1.0 -0.6 0.2 -1.0 -0.2 -0.6 -0.7 -1.3 -0.4
Cardiovascular Disease 3.6 11.8 37.0 4.8 3.0 3.6 5.0 -4.8 2.0 -3.7 3.4 6.1 2.3 2.5 4.6 3.2 3.4 4.7 1.9 4.8 4.6 4.8 3.7 2.4 -0.1 4.7 3.4 3.6 3.8 2.3 1.1 1.6 4.2 0.7 2.4 1.0 2.6 2.4 3.4 0.7 -0.5 3.7
Hypothyroidism (self reported) 0.3 0.8 3.3 0.7 0.5 -0.3 0.5 -0.9 0.3 -0.7 0.8 0.4 1.0 -0.2 0.8 -0.1 0.7 0.6 -0.2 0.6 0.8 0.2 1.1 0.4 1.0 0.6 1.2 0.8 1.0 0.6 1.6 1.2 1.0 0.8 0.5 1.3 1.6 1.6 1.2 1.8 1.0 1.0
Respiratory disease 1.2 2.7 9.8 2.1 2.0 3.1 2.2 -2.0 -0.6 -2.0 0.8 1.9 0.1 1.2 2.0 1.4 1.8 2.0 0.8 2.0 2.2 1.7 1.7 1.0 0.3 1.9 1.1 2.1 1.9 1.2 1.6 1.2 1.9 0.3 1.3 1.4 1.9 1.7 1.2 1.5 0.8 1.6
Type 2 Diabetes (T2D) (2018) 2.9 5.5 8.9 2.7 2.9 1.7 2.3 -2.8 2.0 -2.3 1.2 2.9 3.0 2.2 2.8 2.2 2.9 2.8 2.7 2.7 2.7 2.7 2.6 2.6 1.2 2.7 1.8 2.4 2.9 2.2 1.5 1.5 2.6 1.5 2.2 2.2 2.2 2.1 2.1 1.4 0.5 2.7
Lung FEV1/FVC ratio 0.1 0.4 3.6 -0.5 -0.0 -0.2 -0.7 0.4 -0.7 0.3 0.5 -1.8 0.3 -0.6 -0.5 -0.6 -0.5 -0.5 -0.2 -0.1 -0.5 -0.5 -1.0 -0.1 0.9 -0.6 0.3 -0.3 -0.2 -0.4 -0.7 0.1 -0.3 0.2 -0.5 -1.9 -0.5 -0.8 -0.9 0.4 0.0 -0.7
Lung FVC 0.3 1.8 20.6 0.1 0.6 1.2 -1.2 -0.3 2.1 -0.7 -4.5 -1.5 0.8 -0.5 0.4 -1.1 1.1 0.4 1.0 -0.5 0.4 -0.5 0.6 0.6 0.3 0.1 -0.4 0.7 0.8 1.2 2.0 0.5 0.1 0.8 0.3 3.4 0.6 1.5 1.7 1.0 2.0 0.8
Neuroticism 0.5 1.2 5.2 0.9 1.5 1.4 0.5 -1.0 -0.1 -1.2 0.1 0.4 1.0 0.7 1.0 0.5 1.3 0.7 0.9 0.9 0.9 0.6 0.7 0.8 1.6 0.9 1.1 1.5 1.2 0.9 1.0 1.9 1.3 1.3 1.0 -0.0 1.2 1.1 0.8 1.7 2.3 1.1
Chronotype (morning person) 3.4 7.8 23.4 1.5 3.7 0.3 1.3 -0.6 1.6 -2.1 -0.6 3.2 1.0 3.8 1.2 3.1 2.4 1.3 4.8 1.3 1.4 2.2 3.1 3.0 4.4 1.7 1.5 3.0 1.9 4.1 3.0 4.2 2.5 4.3 4.1 2.4 3.5 2.2 2.6 2.0 4.1 2.9
Hair Pigment 0.2 4.6 11.6 3.1 1.4 3.4 3.4 -3.0 -0.7 -2.4 2.1 3.3 0.1 2.2 2.8 2.7 1.7 3.4 1.2 3.3 2.7 3.3 2.0 1.8 -0.1 3.0 1.7 1.9 1.8 0.8 -0.1 0.3 2.2 -0.8 0.8 0.2 0.7 0.6 2.8 -0.4 -1.3 2.2
Tanning 0.2 2.4 11.2 -2.0 -0.6 -3.4 -2.2 2.1 -0.7 1.4 -2.5 -2.3 -0.8 -1.0 -1.9 -1.4 -1.1 -2.3 -0.6 -2.4 -1.9 -2.1 -0.9 -0.8 0.6 -2.1 -1.2 -0.7 -0.9 0.3 1.6 0.6 -1.4 1.0 0.2 1.8 0.3 -0.1 -0.6 0.7 2.1 -1.2
Hand grip strength (left) 0.6 1.7 5.4 -2.1 -0.4 -1.5 -1.9 2.3 -0.1 1.7 -1.5 -1.3 -0.8 0.5 -1.9 -0.1 -1.4 -2.2 0.8 -2.0 -2.1 -1.3 -0.9 -0.5 1.6 -1.7 -1.4 -0.7 -1.6 0.4 0.1 1.1 -1.0 1.2 0.7 -0.2 0.3 -0.7 -0.4 -0.9 1.9 -1.0
Number of treatments/medications taken 4.3 7.8 16.1 3.8 3.1 1.8 4.0 -3.8 1.9 -3.2 3.3 3.0 2.5 2.0 3.6 2.5 2.7 3.6 1.9 3.8 3.6 3.5 2.8 2.5 1.1 3.5 3.3 3.1 3.1 2.2 1.7 2.1 3.3 1.3 2.5 0.9 2.5 2.1 2.0 2.1 0.9 2.8
Average weekly spirits intake 0.4 0.5 2.2 1.0 0.1 0.7 1.3 -1.0 -0.2 -0.7 1.5 1.2 -0.4 -0.1 0.8 0.3 0.2 0.9 -0.8 0.9 1.0 1.0 0.4 -0.4 -1.2 0.9 0.7 0.5 0.5 -0.3 -0.3 0.5 0.8 -0.5 0.3 -0.4 0.6 0.1 0.2 0.1 -0.1 0.4
Sensitivity / hurt feelings 1.4 2.4 6.3 1.5 1.9 0.9 0.8 -0.9 2.3 -1.6 0.5 1.1 2.1 2.3 1.1 2.0 1.4 1.3 2.5 1.2 1.1 1.5 1.6 2.1 2.3 1.3 0.5 1.6 1.2 2.0 1.4 1.5 1.3 1.9 1.8 1.1 1.3 0.7 2.0 1.1 1.5 1.7
Frequency of depressed mood in last 2 weeks 0.5 0.6 3.6 0.6 0.7 0.5 0.9 -0.5 -1.1 -0.6 1.9 1.0 0.3 0.6 0.5 0.7 0.3 0.6 -0.0 0.8 0.4 0.6 0.7 0.4 1.4 0.5 0.7 0.9 0.5 0.8 0.8 1.4 0.9 0.7 1.0 -0.1 1.2 0.4 0.8 0.5 0.6 0.6
Hearing difficulty/problems: Yes 1.5 2.3 8.3 -2.1 -0.6 -1.4 -2.5 1.5 -0.5 1.6 -2.7 -2.9 -0.3 -1.6 -1.5 -2.1 -0.5 -2.0 -0.5 -2.3 -1.6 -2.6 -1.5 -0.9 -0.2 -2.1 -1.2 -1.1 -0.6 -0.7 0.9 -1.1 -1.7 -0.7 -1.5 1.4 -0.7 0.4 -1.1 0.7 0.3 -1.5
Relative age of first facial hair 2.4 5.0 8.5 2.4 2.4 1.6 2.8 -2.6 -1.6 -2.5 1.1 1.6 1.3 1.3 2.6 1.5 2.5 2.5 1.2 2.9 2.6 2.0 2.3 2.3 2.4 2.4 2.5 2.5 2.4 1.9 2.5 2.5 2.6 1.8 2.4 1.6 2.2 2.5 2.1 2.6 2.3 2.2
Other serious medical condition/disability diagnosed by doctor 1.4 1.8 5.7 1.4 1.9 1.3 0.8 -1.8 0.9 -1.5 -0.6 -0.5 1.6 0.0 1.7 -0.1 2.1 1.3 0.9 1.1 1.8 0.6 1.3 1.3 0.8 1.4 1.1 1.6 1.9 1.0 1.6 1.1 1.4 0.7 0.5 1.1 1.5 2.1 0.8 2.4 1.0 1.4
Ever used hormone-replacement therapy (HRT) 0.5 0.6 1.6 0.8 1.3 0.6 0.8 -0.6 0.3 -0.5 1.2 0.3 0.3 1.1 0.7 1.1 0.8 0.6 1.2 0.8 0.7 1.0 1.0 0.9 0.7 0.8 0.4 0.8 0.6 0.9 0.5 0.7 0.8 0.7 0.9 0.3 1.1 0.5 0.5 0.7 0.3 0.9
Ever had hysterectomy (womb removed) 0.5 0.5 3.0 0.8 0.6 1.6 1.3 -0.8 0.0 -0.8 1.7 1.4 -0.2 0.8 0.7 1.0 0.5 0.8 0.3 1.0 0.7 1.0 0.6 0.0 -0.0 0.8 0.7 0.8 0.6 0.2 0.0 0.2 0.6 -0.5 0.1 -0.5 0.1 0.2 0.0 0.2 -0.3 0.6
Systolic blood pressure, automated reading 0.7 2.0 8.5 -1.0 -1.1 -2.0 -1.3 1.3 2.6 1.5 -1.3 -0.9 -0.7 0.9 -1.2 0.6 -0.9 -1.1 1.0 -1.1 -1.4 0.0 -1.0 -0.4 -1.4 -0.8 -2.7 -1.6 -1.2 -0.5 -2.5 -1.5 -1.2 -0.3 -0.6 -1.4 -1.9 -2.3 -0.5 -2.9 -1.2 -0.8
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 1.7 -0.5 -0.5 -0.4 -0.6 0.7 -1.3 0.6 -0.9 -0.2 -1.3 -0.1 -0.6 -0.2 -0.4 -0.4 -0.3 -0.5 -0.6 -0.5 -0.5 -0.6 -0.4 -0.7 -0.4 -0.6 -0.6 -0.7 -1.1 -0.9 -0.6 -1.0 -0.8 -0.2 -0.6 -0.8 -1.0 -1.0 -1.3 -0.5
Angina 3.7 4.8 10.9 2.5 2.5 1.8 2.6 -2.9 0.2 -2.2 0.9 1.8 1.6 0.7 2.8 1.0 2.7 2.6 1.2 2.3 2.9 1.9 2.5 1.8 1.0 2.5 2.3 2.4 3.0 1.7 2.6 1.8 2.7 1.3 1.9 2.6 2.6 3.3 2.0 2.4 1.6 2.4
Medication for hormone replacement therapy 2.6 2.9 5.5 1.9 2.4 0.8 1.8 -2.0 -0.8 -1.6 0.7 1.4 0.6 1.2 1.9 1.3 1.7 1.5 1.9 2.1 1.9 1.9 2.0 1.4 1.4 1.9 2.3 2.0 1.7 1.6 1.5 2.0 2.2 1.4 1.9 0.5 2.3 1.6 1.4 1.7 1.3 1.9
Vitamin and mineral supplements 0.9 1.2 4.0 -1.2 -1.2 -0.6 -1.1 0.9 -1.4 1.2 -0.8 -2.0 -1.6 -1.6 -1.0 -1.5 -0.9 -1.3 -1.4 -1.2 -0.9 -1.4 -1.0 -1.4 -1.5 -1.1 -1.5 -1.1 -0.7 -1.0 -0.1 -0.7 -0.9 -0.6 -1.2 -0.7 -0.6 -0.3 -1.2 0.7 -0.0 -1.1
Supplements: Zinc 0.3 0.4 1.0 -0.8 -0.3 -0.6 -0.6 0.6 0.7 0.3 -0.4 -0.4 -0.0 -0.3 -0.6 -0.4 -0.2 -0.5 -0.5 -0.8 -0.6 -0.8 -0.9 -0.4 -0.5 -0.7 -0.4 -0.4 -0.5 -0.7 -0.6 -0.6 -0.8 -1.0 -0.9 -0.3 -0.9 -0.1 -1.0 -0.9 -0.5 -0.7
Medication: Co-codamol 2.8 3.2 6.9 1.7 2.0 2.6 1.7 -1.4 -0.2 -1.8 1.7 1.8 1.7 1.8 1.6 1.9 1.5 1.8 2.1 1.9 1.5 2.1 1.8 1.9 2.3 1.7 2.0 2.0 1.8 1.9 1.1 2.2 1.9 2.2 2.0 0.8 2.0 1.3 1.6 1.4 1.6 1.9
Medication: Metformin 2.9 4.0 6.2 2.4 2.4 0.7 2.2 -2.2 0.5 -2.0 1.3 2.1 2.0 1.8 2.3 1.9 2.2 2.5 2.2 2.4 2.3 2.2 2.3 2.2 1.6 2.2 2.1 2.1 2.4 2.1 1.9 1.5 2.1 1.2 1.8 2.3 1.9 1.7 2.3 1.6 0.8 2.2
Diabetes (father) 0.1 0.1 1.0 0.1 0.2 -0.0 0.4 -0.3 -0.5 0.3 1.0 -0.1 -0.6 -0.0 0.3 0.1 -0.1 0.0 0.3 0.3 0.3 0.2 0.2 -0.1 -1.0 0.2 -0.1 -0.1 0.2 0.0 0.3 -0.5 0.0 -0.6 -0.1 0.3 -0.1 0.1 0.1 -0.1 -0.9 -0.0
Diabetes (mother) 1.3 1.6 4.5 1.2 2.0 1.2 1.2 -1.1 -0.3 -1.3 -0.1 1.4 0.3 1.6 1.2 1.5 2.1 1.1 2.0 0.9 1.3 1.2 1.3 0.9 0.4 1.1 0.4 1.4 1.7 1.4 1.4 1.1 1.3 0.9 1.1 1.3 1.3 1.5 0.9 1.6 1.1 1.4
Severe depression (siblings) 0.6 0.7 2.4 -0.8 -0.4 -0.9 -1.2 0.9 0.7 1.0 -1.4 -1.5 -0.9 -0.7 -0.9 -0.9 -0.8 -1.1 -0.3 -1.0 -0.8 -0.9 -0.7 -0.4 -0.9 -0.9 -1.5 -0.8 -1.1 -0.6 -0.6 -0.5 -0.9 -0.5 -0.6 -0.2 -0.2 -0.8 -0.9 -0.4 -0.0 -0.8
Pack years adult smoking proportion 0.8 1.2 14.3 0.7 0.6 0.9 1.4 0.0 -0.6 -0.3 3.8 1.8 -0.5 1.9 0.1 2.1 -0.0 0.4 0.8 0.9 0.2 1.3 1.0 0.6 1.7 0.5 0.5 0.6 -0.1 0.9 0.5 1.0 0.7 0.7 1.1 -1.5 0.6 -0.7 1.0 0.3 -0.3 0.6
Impedance of leg (right) 0.4 2.0 14.7 0.3 0.9 0.1 0.5 0.2 3.8 -1.0 0.0 1.0 1.0 3.0 0.3 2.5 1.1 0.2 2.8 0.1 0.3 1.3 1.1 1.7 1.6 0.8 -0.1 0.7 0.4 2.1 0.2 1.4 0.7 2.8 2.1 0.5 0.0 0.3 0.9 -0.2 2.2 1.2
Leg fat-free mass (left) 0.4 2.2 23.4 0.9 1.7 1.0 1.1 -1.3 -4.8 -0.6 0.7 1.6 -0.7 -0.8 1.1 -0.6 0.7 0.8 -0.6 1.3 1.0 0.1 1.1 0.2 1.3 0.5 1.6 1.6 1.3 0.3 2.3 1.9 1.6 -0.4 0.5 1.3 3.2 1.9 0.9 2.4 0.6 0.8
Trunk fat percentage 1.8 7.2 13.8 3.2 3.0 2.6 3.4 -3.2 -0.6 -2.6 3.0 3.4 2.2 1.4 3.1 1.8 2.6 3.2 1.1 3.4 3.1 2.9 2.7 2.1 1.4 2.8 3.2 3.2 3.1 2.3 2.3 3.3 3.4 1.6 2.7 2.0 3.7 2.5 2.1 2.5 1.6 2.6
Hand grip strength (right) 0.4 1.2 4.9 -1.5 0.3 -0.9 -1.6 1.7 0.2 1.1 -1.4 -1.3 -0.6 0.7 -1.3 0.1 -0.8 -1.6 1.2 -1.4 -1.5 -0.9 -0.3 -0.1 2.0 -1.2 -0.9 -0.1 -1.1 0.6 0.6 1.5 -0.3 1.6 0.8 -0.4 0.9 -0.2 0.2 0.2 2.2 -0.3
Townsend deprivation index at recruitment 1.7 2.4 8.3 1.8 1.5 1.3 2.3 -1.8 -0.8 -1.6 2.9 1.7 1.1 1.0 1.6 1.4 1.3 1.6 0.5 1.9 1.7 1.7 1.4 1.0 1.1 1.7 2.5 1.7 1.6 1.2 1.6 1.6 1.8 1.1 1.3 -0.2 1.3 1.2 1.9 1.3 0.8 1.4
Current tobacco smoking 0.7 1.1 9.6 1.4 0.5 1.4 2.0 -1.1 -0.8 -0.9 3.1 1.7 0.3 0.6 0.9 1.1 0.2 1.1 -0.2 1.5 1.1 1.5 0.9 0.2 0.1 1.2 0.8 0.8 0.5 0.2 0.1 1.1 1.2 0.0 0.6 -1.6 0.7 -0.2 0.8 0.7 -0.1 0.8
Average weekly fortified wine intake 0.2 0.3 1.5 0.1 0.4 -0.1 -0.4 -0.3 0.5 0.0 -0.8 -0.6 1.2 -0.4 0.3 -0.6 0.5 0.0 0.2 -0.2 0.3 -0.3 0.5 0.2 0.5 0.2 0.3 0.2 0.4 0.4 0.6 0.2 0.3 0.6 0.4 1.1 0.9 1.0 0.4 0.4 0.7 0.4
Maternal smoking around birth 0.5 0.7 2.1 -0.5 -1.0 0.6 -0.0 0.6 -1.4 0.5 1.3 0.8 -0.9 -0.6 -0.7 -0.3 -0.9 -0.1 -1.3 -0.2 -0.6 -0.4 -0.8 -1.1 -0.2 -0.6 0.4 -0.6 -0.8 -0.9 -1.0 -0.7 -0.6 -1.3 -1.1 -1.3 -0.7 -0.9 -0.8 -1.1 -1.4 -0.8
Fed-up feelings 3.2 5.8 12.7 2.5 3.1 1.8 2.4 -2.4 -0.7 -2.5 1.6 2.3 1.5 1.6 2.4 1.7 2.5 2.4 1.7 2.5 2.3 2.1 2.4 1.9 2.7 2.2 2.4 3.0 2.6 2.3 2.7 3.6 3.0 2.2 2.4 1.3 3.4 2.6 2.5 2.9 3.0 2.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 5.2 0.5 0.7 1.3 0.8 -0.4 -2.3 -0.6 1.4 1.0 0.3 -0.1 0.4 0.1 0.4 0.6 -0.4 0.9 0.4 0.4 0.7 0.1 1.4 0.3 1.1 1.0 0.9 0.7 1.3 1.5 0.9 0.6 0.9 0.5 1.2 0.7 1.1 0.7 1.0 0.5
Relative age voice broke 1.6 2.4 8.5 0.7 1.7 -0.2 0.8 -0.6 0.3 -1.1 0.2 0.9 1.4 0.5 0.8 0.5 1.1 0.6 0.9 0.9 0.8 0.5 1.5 1.6 2.9 0.7 1.3 1.5 1.1 2.0 2.8 2.7 1.4 2.4 2.1 2.0 2.2 1.8 1.6 2.3 2.9 1.3
Taking other prescription medications 1.9 2.9 6.4 1.8 2.0 0.2 1.4 -2.0 1.2 -1.7 0.7 1.0 2.0 0.6 2.0 0.7 2.2 1.5 1.0 1.3 2.0 1.2 2.1 1.5 0.9 1.7 1.4 1.9 2.3 1.6 2.4 1.7 2.0 1.7 1.7 2.0 2.3 2.5 1.8 2.3 1.4 2.0
Age when periods started (menarche) 1.4 3.4 6.0 1.9 1.7 1.3 1.8 -1.8 1.8 -2.3 -0.5 2.4 1.9 2.0 2.0 1.9 2.1 2.0 2.1 1.6 1.9 1.9 1.9 2.3 1.8 2.1 1.2 2.1 2.1 1.9 1.3 1.8 1.9 1.6 2.0 2.1 1.4 2.1 1.5 1.1 1.9 2.2
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 5.7 0.6 1.2 1.6 0.8 -0.8 1.2 -1.0 0.7 0.4 0.5 0.1 0.8 0.2 1.4 0.5 0.3 0.4 1.1 0.5 1.2 0.1 -0.1 0.7 0.1 1.2 1.0 0.8 1.6 1.5 1.1 1.0 0.8 0.6 1.5 1.9 0.1 2.4 1.7 1.0
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 2.9 -0.4 -0.2 -0.7 -0.9 0.4 1.7 0.1 -1.5 -0.5 0.8 0.4 -0.3 0.1 0.2 -0.1 0.6 -0.9 -0.4 -0.5 -0.0 0.1 -0.2 -0.4 0.3 -0.2 -0.2 0.2 0.0 -0.7 -0.6 -0.1 -0.5 1.7 -0.2 0.4 0.1 -0.4 -0.1 0.1
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 4.2 1.0 0.9 0.5 1.1 -1.2 2.1 -0.8 1.4 0.3 1.6 1.5 1.2 1.5 1.4 0.9 1.3 1.0 1.1 1.2 0.9 1.7 0.8 1.3 0.8 0.7 1.1 0.7 0.2 0.1 0.7 0.4 0.5 0.4 -0.1 0.6 0.9 0.6 0.4 1.0
Qualifications: CSEs or equivalent 1.4 1.9 6.6 0.9 1.5 0.2 1.3 -1.1 -0.2 -1.3 1.5 2.6 0.8 0.6 1.1 0.8 1.2 0.7 0.5 0.9 1.2 0.9 1.7 0.6 1.4 1.1 1.8 1.5 1.2 1.2 2.0 2.1 1.6 1.3 1.3 0.7 2.2 2.2 1.2 1.9 1.2 1.4
Serious illness, injury or assault to yourself 1.4 1.7 6.8 -1.2 -1.0 -2.6 -1.2 0.8 -0.7 1.4 -0.4 -0.8 -0.6 -2.2 -1.0 -2.1 -1.2 -1.5 -1.7 -1.4 -1.1 -1.7 -1.4 -1.3 -1.8 -1.3 -0.6 -1.4 -1.0 -1.6 -0.5 -1.2 -1.2 -1.2 -1.5 -0.3 -0.5 -0.4 -1.1 -0.3 -1.2 -1.4
High blood pressure 0.9 2.5 9.5 2.2 1.1 1.7 2.4 -1.8 1.4 -1.1 2.5 3.1 1.3 1.9 1.7 2.3 1.0 2.0 1.3 2.3 1.8 2.7 1.3 1.3 -0.6 2.0 1.0 1.1 1.1 0.8 -0.5 -0.0 1.5 -0.2 1.0 -0.7 0.4 -0.3 1.3 -0.9 -1.5 1.2
Hayfever, allergic rhinitis or eczema 0.1 0.3 3.2 0.1 -0.1 -0.1 -0.2 -0.2 1.4 -0.0 -1.8 -1.0 0.2 0.1 0.3 -0.1 0.1 -0.1 0.3 -0.2 0.2 -0.1 0.1 0.5 -0.8 0.2 -1.2 -0.1 0.2 0.2 0.2 -0.8 -0.2 -0.3 -0.2 0.9 -0.4 0.2 -0.2 -0.2 -0.7 0.0
Multivitamins +/- minerals 0.8 1.0 6.2 1.1 0.7 0.4 1.1 -0.5 1.3 -0.9 1.5 2.5 1.3 1.5 0.5 1.6 0.2 1.1 0.9 1.3 0.6 1.5 0.7 0.9 1.2 0.9 1.6 0.8 0.2 0.7 -0.8 0.4 0.6 0.1 0.8 -0.1 0.3 -0.8 0.7 -1.4 -0.9 0.6
Stomach or abdominal pain in last month 1.4 1.8 7.0 0.8 1.7 -0.0 0.9 -1.2 -1.4 -1.4 -0.7 -0.7 0.6 0.4 1.2 0.4 1.8 0.7 0.7 0.8 1.2 0.2 1.0 1.0 1.6 0.9 0.9 1.4 1.6 1.2 2.5 1.7 1.2 1.4 1.4 1.0 1.5 2.0 1.3 2.7 2.4 1.1
Supplements: Glucosamine 0.5 0.6 2.5 -0.5 -0.3 -1.2 -0.8 0.8 1.5 0.8 -0.8 0.3 -1.0 -0.2 -0.8 -0.4 -0.8 -0.6 0.0 -0.6 -0.8 -0.4 -0.5 -0.7 -0.8 -0.8 -1.6 -0.7 -1.0 -0.5 -0.9 -0.8 -0.6 -0.8 -0.5 -0.0 -0.2 -1.0 -0.6 -1.2 -1.1 -0.6
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 1.5 0.8 0.6 0.3 0.7 -0.9 -1.0 -0.7 -0.7 -0.1 0.3 0.3 0.9 0.3 1.2 1.0 0.3 1.1 1.0 0.6 0.7 0.9 0.9 0.8 0.7 0.8 1.2 0.6 0.8 0.7 0.9 0.8 0.7 0.8 0.7 1.0 0.5 1.1 0.8 0.7
Medication: Atenolol 2.7 3.4 7.4 2.6 1.8 1.6 2.6 -2.7 -0.1 -2.0 0.9 2.4 1.3 1.3 2.6 1.6 2.0 2.7 1.3 2.7 2.7 2.5 1.9 1.6 0.1 2.6 1.8 1.9 2.3 1.4 0.9 0.8 2.2 0.5 1.5 0.9 1.4 1.5 1.8 0.5 0.1 2.0
Medication: Levothyroxine sodium 0.2 0.3 2.3 0.6 0.1 0.4 0.6 -0.5 -0.4 -0.5 1.5 1.1 0.3 -0.3 0.4 -0.0 -0.0 0.5 -0.5 0.6 0.5 0.3 0.7 -0.1 0.5 0.4 1.2 0.3 0.2 -0.1 0.4 0.4 0.6 0.2 -0.0 0.3 1.1 0.8 0.5 0.7 -0.3 0.5
Sitting height 0.2 1.4 14.8 -0.4 1.0 1.0 -0.2 0.1 -3.9 -0.1 -2.1 1.9 -2.1 -0.2 0.0 -0.5 0.5 -0.2 -0.0 -0.2 -0.0 -0.6 0.5 -0.6 0.9 -0.3 0.4 1.1 0.3 0.3 1.5 1.4 0.5 -0.5 0.3 2.1 2.0 1.6 0.6 0.2 1.6 0.4
Chronic bronchitis/emphysema (father) 1.3 1.6 4.3 -1.6 -1.3 -0.9 -1.6 1.8 1.5 1.4 0.1 -0.0 -0.1 -0.4 -1.7 -0.6 -1.3 -1.5 -0.7 -1.9 -1.7 -1.4 -1.3 -1.0 -0.5 -1.7 -2.1 -1.3 -1.5 -0.6 -0.8 -1.1 -1.7 -0.7 -0.9 -0.1 -1.4 -1.0 -1.1 -1.5 -0.9 -1.3
High blood pressure (mother) 0.2 0.3 1.5 0.6 0.3 0.4 0.4 -0.3 0.5 -0.4 0.2 1.1 -0.1 1.2 0.4 1.1 0.1 0.4 0.9 0.8 0.3 1.0 0.6 0.9 0.4 0.7 0.1 0.4 0.1 0.5 -0.6 0.5 0.5 0.5 0.6 -0.6 0.2 -0.6 0.3 -0.4 -0.1 0.6
Body mass index (BMI) 1.6 6.7 13.2 3.3 2.9 3.0 3.5 -3.6 -1.6 -2.3 3.4 3.0 2.2 0.7 3.3 1.4 2.5 3.4 0.6 3.6 3.3 2.7 2.5 1.6 0.5 2.9 3.1 2.9 3.3 1.6 2.5 2.2 3.1 0.2 1.7 1.8 3.2 2.5 2.3 2.7 0.4 2.4
Impedance of leg (left) 0.5 2.4 13.5 0.5 1.2 0.0 0.7 0.0 3.7 -1.3 0.0 1.2 0.9 3.2 0.5 2.8 1.3 0.3 3.0 0.2 0.4 1.4 1.2 1.8 1.8 1.0 0.1 1.0 0.6 2.3 0.3 1.7 0.9 3.0 2.3 0.3 0.2 0.5 1.0 -0.1 2.5 1.3
Leg predicted mass (left) 0.4 2.1 22.8 0.9 1.7 1.0 1.0 -1.2 -4.8 -0.6 0.6 1.7 -0.7 -0.8 1.1 -0.6 0.7 0.8 -0.6 1.3 1.0 0.2 1.0 0.2 1.3 0.5 1.6 1.6 1.2 0.3 2.3 1.9 1.6 -0.4 0.5 1.2 3.1 1.8 0.9 2.3 0.6 0.8
Trunk fat mass 1.5 6.6 15.4 2.9 3.0 2.7 3.1 -2.9 -1.9 -2.3 2.7 3.5 1.5 1.2 2.8 1.6 2.4 2.9 1.0 3.2 2.8 2.5 2.6 1.8 1.6 2.5 3.1 3.1 2.9 2.1 2.5 3.3 3.3 1.2 2.4 2.0 3.9 2.5 2.1 2.6 1.5 2.4
Waist circumference 2.3 8.4 14.4 3.4 3.5 3.3 3.7 -3.5 -1.4 -2.9 3.6 3.8 2.5 1.8 3.4 2.2 3.0 3.4 1.7 3.7 3.4 3.0 2.9 2.3 1.8 3.0 3.6 3.5 3.5 2.3 2.8 2.7 3.4 0.8 2.2 1.9 3.4 2.8 2.3 3.0 0.8 2.8
Number of incorrect matches in round 1.9 3.1 6.9 1.8 1.6 2.1 1.9 -1.9 1.8 -1.7 2.1 0.7 2.6 2.2 2.0 2.2 1.9 2.0 2.0 2.0 1.8 1.9 1.9 2.4 1.9 2.0 1.9 1.6 1.9 2.1 1.2 0.5 1.4 1.4 1.4 1.1 0.5 1.5 1.2 1.2 0.4 1.9
Past tobacco smoking 1.1 1.9 6.9 -2.1 -1.4 -1.8 -1.8 2.6 1.1 1.7 -0.8 -1.1 -0.7 0.7 -2.2 0.2 -1.4 -2.0 0.4 -1.8 -2.2 -1.1 -1.0 -0.1 1.2 -1.7 -1.2 -1.4 -1.7 0.4 -0.9 -0.3 -1.8 0.9 0.2 0.1 -1.7 -1.7 -1.0 -1.8 0.3 -1.2
Alcohol usually taken with meals 0.4 0.6 1.8 0.8 0.7 0.5 0.3 -0.6 1.1 -0.6 -0.1 -0.1 0.7 1.1 0.7 0.9 0.3 0.6 1.3 0.9 0.6 1.0 0.4 1.3 1.0 1.0 0.3 0.6 0.5 0.7 -0.6 0.4 0.6 1.3 0.8 -0.8 -0.0 -0.5 0.9 -0.3 0.6 0.7
Nervous feelings 0.3 0.5 2.3 0.1 0.9 0.4 -0.2 -0.0 1.3 -0.9 -0.1 -0.6 1.2 1.3 0.2 1.0 1.1 0.1 1.4 -0.1 0.1 0.0 0.2 1.0 1.5 0.2 0.1 0.7 0.6 0.6 0.4 0.5 0.2 0.6 0.1 -0.5 -0.1 0.5 0.2 1.0 1.0 0.6
Frequency of tenseness / restlessness in last 2 weeks 2.8 4.4 7.8 2.3 2.1 2.6 2.3 -2.1 -0.4 -2.4 1.2 1.0 1.5 1.8 2.1 1.9 2.1 2.4 1.7 2.6 2.1 2.4 2.1 2.0 2.3 2.2 2.1 2.6 2.2 2.3 1.8 2.8 2.4 2.2 2.6 1.2 2.2 1.4 2.0 1.7 2.3 2.1
Hearing difficulty/problems with background noise 1.1 1.7 7.6 -1.6 0.1 -2.8 -1.9 0.9 -0.9 0.8 -2.2 -2.5 -0.7 -1.7 -1.0 -2.0 -0.0 -1.8 -0.5 -2.0 -1.0 -2.3 -1.3 -1.0 -0.3 -1.6 -0.6 -0.6 -0.3 -0.8 1.0 -0.4 -1.0 -0.6 -1.4 -0.0 -0.1 0.7 -1.1 1.6 0.6 -1.1
Hair/balding pattern: Pattern 2 0.7 0.9 2.9 0.5 0.9 -0.3 0.4 -0.3 -0.1 -0.3 -0.4 0.6 0.3 1.3 0.6 1.0 0.9 0.3 1.5 0.6 0.6 0.9 1.3 1.2 1.4 0.8 0.5 0.7 0.8 1.6 0.8 1.3 1.0 1.7 1.5 1.1 1.4 0.7 0.8 0.4 1.1 1.1
Had menopause 1.5 1.9 3.1 1.5 1.5 0.7 1.4 -1.4 1.1 -1.3 -0.1 0.5 1.4 1.6 1.5 1.5 1.7 1.6 1.8 1.3 1.6 1.6 1.5 1.6 0.7 1.5 1.4 1.4 1.6 1.7 0.9 1.2 1.2 1.1 1.6 1.6 0.8 1.2 1.4 0.7 1.5 1.6
Had other major operations 0.6 0.7 2.9 0.6 1.4 -0.1 0.3 -0.6 0.2 -0.6 -0.4 0.8 0.8 0.3 0.6 0.2 1.1 0.4 0.8 0.2 0.7 0.3 0.9 0.5 0.7 0.5 0.6 1.0 1.1 0.8 1.1 1.3 1.1 0.9 0.8 0.9 1.7 1.4 0.4 1.1 0.9 0.9
Forced vital capacity (FVC) 0.4 1.6 17.5 -1.4 0.6 0.3 -2.0 1.3 0.4 0.4 -4.2 -0.7 -0.7 0.1 -0.9 -0.7 0.3 -1.3 1.3 -1.5 -1.0 -1.4 0.1 0.1 1.6 -1.1 -1.1 0.3 -0.3 1.1 1.7 1.0 -0.5 1.2 0.4 2.5 0.9 1.2 0.2 0.6 2.4 0.1
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 4.5 -0.2 0.2 -0.2 -0.7 0.4 2.0 -0.1 -1.4 -0.2 1.5 0.9 -0.2 0.6 0.4 0.0 1.3 -0.7 -0.2 -0.0 0.4 0.6 0.3 -0.1 0.4 0.1 0.1 0.9 0.3 -0.1 -0.2 0.7 0.1 2.1 0.3 0.6 0.3 -0.2 0.4 0.5
Ever unenthusiastic/disinterested for a whole week 2.4 3.0 11.0 -1.4 -1.8 -0.2 -1.0 1.1 -3.3 1.6 0.0 -1.9 -1.7 -2.0 -1.4 -1.7 -1.6 -1.4 -2.2 -1.3 -1.3 -1.6 -1.8 -1.7 -1.9 -1.5 -0.9 -1.8 -1.5 -2.3 -1.7 -1.8 -1.6 -2.2 -2.3 -2.1 -1.7 -1.3 -2.2 -0.7 -1.8 -1.8
Qualifications: None of the above 3.3 7.0 13.5 2.1 3.1 2.6 2.4 -1.9 -0.1 -2.1 1.6 1.2 2.0 2.5 2.2 2.5 3.0 2.1 2.6 2.2 2.3 2.3 2.9 2.6 2.5 2.1 2.7 2.9 2.7 3.5 3.5 3.7 2.7 3.1 3.3 3.0 3.2 3.0 2.3 2.9 3.4 2.6
Financial difficulties in last 2 years 1.3 1.8 4.7 2.0 0.9 1.5 1.9 -1.9 -0.8 -1.8 2.2 1.9 0.5 -0.5 1.6 0.1 0.9 1.9 -0.8 2.1 1.8 1.3 1.3 0.5 0.6 1.6 1.7 1.4 1.1 0.2 0.7 1.2 1.9 0.3 0.6 -0.4 1.8 1.0 0.8 1.7 -0.2 1.3
Mouth/teeth dental problems 0.3 0.5 5.3 -0.3 -0.7 -2.0 -0.2 -0.1 2.3 0.5 0.5 0.2 0.4 -0.7 -0.0 -0.6 -0.5 -0.5 -0.7 -0.4 -0.2 -0.3 -0.3 -0.5 -0.9 -0.0 -0.1 -0.6 -0.2 -0.8 -0.7 -0.8 -0.3 -0.8 -0.7 -0.6 -0.7 -0.2 -0.2 -0.8 -1.0 -0.3
Heart attack 0.3 0.4 6.6 0.1 -0.3 -0.1 0.6 -0.3 -2.6 0.2 0.8 0.9 -0.4 -0.5 0.2 -0.2 -0.3 0.1 -0.8 0.4 0.2 0.0 -0.2 -0.2 -0.5 0.1 0.3 -0.3 0.1 -0.6 -0.1 -0.5 -0.0 -0.6 -0.3 -0.7 -0.3 0.2 -0.4 -0.3 -1.1 -0.4
Allergy 0.1 0.2 1.2 -0.4 -0.1 -0.5 -0.6 0.4 -1.1 0.2 0.3 -0.3 -0.2 -0.6 -0.4 -0.7 -0.2 -0.2 -0.2 -0.1 -0.4 -0.3 0.0 -0.2 1.1 -0.4 0.8 -0.2 -0.3 -0.0 0.2 0.7 -0.1 0.8 0.2 -0.2 0.3 -0.2 0.4 0.4 0.8 -0.0
Pain all over the body in last month 1.4 1.5 5.5 -1.9 -0.9 -2.4 -1.7 1.7 -1.3 1.2 -1.3 -1.3 -0.6 -1.6 -1.6 -1.7 -0.7 -1.8 -1.1 -2.1 -1.5 -2.1 -1.0 -1.1 -0.0 -1.8 -0.5 -1.1 -0.9 -0.7 0.6 -0.4 -1.2 0.1 -0.6 0.2 -0.4 0.3 -1.0 0.3 0.2 -1.2
Diabetes (self-reported) 1.3 2.0 4.0 1.7 2.0 0.9 1.5 -1.8 0.1 -1.1 0.6 1.4 1.5 1.2 1.8 1.2 2.0 1.6 1.7 1.6 1.8 1.5 1.7 1.5 0.4 1.6 1.0 1.4 2.0 1.3 1.5 0.7 1.6 0.2 1.0 1.8 1.6 1.6 1.3 1.2 -0.1 1.6
Hayfever/allergic rhinitis (self-reported) 1.5 2.0 3.9 -1.8 -1.3 -1.2 -1.7 1.5 0.9 1.7 -0.9 -0.5 -0.9 -1.3 -1.5 -1.4 -1.6 -1.8 -1.1 -2.0 -1.7 -1.7 -1.7 -1.6 -1.0 -1.7 -1.4 -1.5 -1.5 -1.6 -1.2 -1.2 -1.4 -1.4 -1.6 -0.8 -1.0 -0.7 -1.3 -1.4 -1.2 -1.6
Medication: Ramipril 1.5 1.9 4.5 1.7 1.6 1.6 2.0 -1.9 1.9 -1.4 2.1 1.4 1.8 1.1 1.8 1.4 1.7 1.6 1.1 1.8 1.9 1.8 1.1 1.2 0.6 1.9 1.4 1.3 1.5 0.9 0.6 0.6 1.5 0.4 1.0 -0.4 0.6 1.0 1.1 0.6 0.1 1.2
Medication: Simvastatin 7.7 11.3 24.2 4.6 3.2 2.6 4.9 -4.8 1.5 -3.5 3.3 4.4 2.5 2.6 4.6 3.3 3.7 4.5 2.0 4.6 4.5 4.5 3.6 2.9 0.1 4.5 2.9 3.5 4.2 2.6 2.0 1.8 4.0 1.0 2.8 2.2 2.8 2.9 3.4 1.7 0.5 3.7
Fluid intelligence score 1.3 2.7 12.4 -0.8 -1.6 -1.9 -1.4 0.7 -0.1 0.9 -2.1 -1.2 -0.6 -0.8 -0.8 -1.0 -0.8 -0.6 -0.3 -0.9 -0.8 -0.9 -1.5 -0.5 -1.9 -0.8 -1.6 -2.0 -1.1 -1.7 -2.9 -3.3 -1.7 -2.4 -2.2 -1.1 -2.4 -1.8 -1.4 -2.5 -3.5 -1.1
Illnesses of siblings 0.6 0.8 4.2 -0.9 -1.2 -1.1 -1.1 1.0 -1.3 0.6 -0.3 -2.1 -0.2 -1.0 -1.0 -1.0 -1.0 -0.9 -1.2 -0.9 -1.0 -1.2 -0.9 -0.3 0.5 -1.1 -0.5 -1.1 -1.1 -0.5 -0.2 -0.5 -1.0 0.3 -0.4 -0.4 -0.8 -0.7 -0.7 0.3 -0.1 -0.9
Neuroticism score 0.8 1.7 5.0 1.2 1.5 1.3 0.9 -0.9 0.4 -1.5 0.7 0.9 1.5 1.5 1.0 1.4 1.3 1.2 1.4 1.2 1.0 1.2 1.1 1.4 2.0 1.1 1.1 1.6 1.2 1.4 1.1 2.0 1.4 1.6 1.4 0.2 1.2 0.9 1.2 1.4 2.2 1.4
Weight 1.2 5.7 15.3 2.5 3.1 2.4 2.8 -2.7 -3.2 -2.0 2.4 3.3 0.8 0.9 2.5 1.2 2.1 2.4 0.8 2.9 2.5 2.0 2.3 1.3 1.7 2.1 2.9 3.0 2.7 1.7 2.8 3.0 3.0 0.6 1.9 1.8 3.9 2.5 2.0 2.7 1.3 2.1
Impedance of arm (right) 0.1 0.4 2.8 -0.0 -1.0 -0.6 -0.2 0.4 1.7 -0.1 -0.7 0.4 -0.5 0.0 -0.4 -0.0 -0.7 -0.2 -0.3 -0.1 -0.3 0.3 -0.3 -0.1 -0.2 0.0 -0.3 -0.5 -0.9 -0.2 -1.6 0.3 0.0 0.9 0.5 -1.0 -0.5 -1.1 -0.4 -1.4 0.3 -0.3
Arm fat percentage (right) 1.9 7.6 16.4 3.8 2.6 3.1 4.0 -3.9 -1.2 -2.7 3.8 3.5 2.3 0.9 3.5 1.6 2.4 3.8 0.3 4.0 3.6 3.2 2.6 1.8 0.6 3.3 3.5 3.0 3.3 1.6 1.8 2.6 3.5 0.7 2.1 1.4 3.3 2.1 2.4 2.3 0.6 2.6
Trunk fat-free mass 0.3 1.5 24.1 -0.0 1.4 0.7 0.4 -0.3 -4.9 -0.0 0.3 1.1 -1.4 -0.1 0.3 -0.1 0.4 -0.1 -0.1 0.4 0.2 -0.3 0.6 0.0 1.5 -0.1 0.8 1.2 0.7 0.4 2.2 1.6 0.8 -0.4 0.3 0.9 2.3 1.5 0.7 1.9 1.0 0.4
Hip circumference 0.9 3.7 13.5 2.3 2.2 1.7 2.5 -2.4 -1.5 -1.4 3.0 3.7 1.1 0.9 2.2 1.3 1.6 2.1 0.6 2.6 2.1 2.1 1.9 1.1 0.4 1.9 2.5 2.2 2.2 1.3 1.7 1.8 2.3 0.1 1.4 1.1 2.7 1.6 1.7 1.6 -0.0 1.8
Time employed in main current job 0.5 0.5 3.8 0.2 0.7 0.2 0.5 0.1 1.0 -0.1 0.6 0.3 0.9 1.9 0.1 1.8 0.5 0.3 1.7 0.5 0.3 0.8 0.4 0.9 0.6 0.5 0.8 0.2 0.1 1.1 -0.3 -0.7 -0.3 0.2 0.6 0.3 -0.8 -0.4 0.1 -1.2 -0.3 0.3
Alcohol intake versus 10 years previously 2.3 3.4 7.2 1.6 1.7 1.4 1.5 -1.2 1.0 -1.5 0.8 1.4 1.7 2.5 1.5 2.3 1.9 1.8 2.2 1.5 1.5 1.9 2.1 1.9 1.6 1.6 1.6 1.8 1.9 2.7 2.2 1.9 1.7 2.5 2.5 2.3 1.7 1.7 2.4 1.1 1.7 2.0
Father’s age at death 1.2 1.6 7.3 -1.4 -1.3 0.6 -1.7 1.6 -0.4 1.2 -1.6 -1.0 -1.3 -0.8 -1.5 -1.0 -1.5 -1.2 -0.6 -1.3 -1.5 -1.3 -1.5 -0.8 -0.3 -1.4 -2.7 -1.2 -1.5 -1.1 -1.1 -0.9 -1.3 -0.5 -1.1 -1.1 -1.1 -1.4 -1.0 -1.0 -0.4 -1.4
Worrier / anxious feelings 0.3 0.7 3.3 0.3 0.2 0.5 -0.0 0.0 1.8 -0.5 -0.8 -0.6 1.2 1.8 0.2 1.4 0.6 0.5 1.8 0.3 0.1 0.7 0.2 1.4 1.0 0.5 -0.7 0.2 0.3 0.9 -0.6 -0.1 -0.1 1.0 0.7 -0.1 -1.0 -0.5 0.5 -0.8 0.8 0.5
Frequency of tiredness / lethargy in last 2 weeks 2.4 3.9 7.3 1.7 2.5 0.6 1.6 -1.7 -0.4 -1.9 1.4 2.0 1.5 1.3 1.8 1.3 2.2 1.4 1.6 1.6 1.8 1.6 2.2 1.8 2.5 1.7 2.0 2.4 2.4 2.3 2.7 2.7 2.2 2.1 2.2 1.5 2.6 2.2 2.2 2.3 2.1 2.2
Falls in the last year 0.5 0.7 2.4 1.1 0.8 0.0 1.3 -1.4 -0.9 -0.9 1.5 1.1 1.1 -0.4 1.1 -0.0 0.8 1.0 -0.5 0.9 1.1 0.6 0.1 -0.1 -0.8 0.9 1.3 0.6 1.0 -0.5 -0.2 0.3 1.1 -0.4 -0.1 -0.9 0.9 0.9 0.1 0.8 -0.5 0.5
Hair/balding pattern: Pattern 3 0.4 0.6 2.0 -0.7 -0.7 -0.0 -1.0 0.7 -0.2 0.5 -0.4 0.3 -0.4 -1.4 -0.7 -1.4 -0.8 -0.6 -1.2 -1.0 -0.8 -1.1 -0.7 -1.2 -1.0 -1.0 -0.7 -0.5 -0.7 -1.2 -0.2 -0.3 -0.5 -0.8 -0.8 0.1 0.1 -0.1 -0.6 0.0 -0.7 -0.6
Number of live births 0.7 1.0 4.1 -0.3 1.3 0.5 -0.6 0.0 -0.7 -0.0 -1.9 -1.4 -0.6 0.2 0.2 -0.2 1.0 -0.3 1.5 -0.4 0.0 -0.4 0.4 0.5 0.8 -0.2 -0.7 0.7 0.8 1.0 1.8 1.4 0.6 1.4 0.8 1.6 1.4 1.4 0.1 1.9 2.0 0.4
Forced expiratory volume in 1-second (FEV1) 0.6 2.0 19.9 -1.9 0.1 -0.3 -2.7 1.6 -0.2 0.9 -4.5 -1.8 -1.1 -1.0 -1.3 -1.7 -0.2 -1.8 0.5 -2.0 -1.4 -2.0 -0.5 -0.5 1.2 -1.6 -1.2 -0.3 -0.6 0.3 1.3 0.6 -0.9 0.8 -0.3 2.0 0.5 0.8 -0.3 0.7 2.0 -0.5
Pulse rate 0.6 1.0 3.2 -1.4 -0.6 -1.2 -1.6 1.4 -0.8 1.1 -1.2 -1.2 -0.7 -1.1 -1.3 -1.4 -0.7 -1.4 -0.8 -1.6 -1.3 -1.8 -0.7 -0.9 -0.2 -1.5 -1.4 -0.9 -0.9 -0.6 0.6 -0.4 -1.1 -0.2 -0.7 0.5 -0.1 -0.1 -0.1 0.3 -0.2 -0.9
Happiness 0.6 0.8 5.3 1.0 0.9 2.3 0.9 -0.8 -0.1 -1.0 0.6 0.6 0.3 0.7 0.8 0.7 0.5 1.0 0.8 1.3 0.7 1.1 0.6 0.7 1.4 0.8 0.3 1.0 0.5 0.5 0.1 1.3 1.0 0.7 0.7 -0.6 0.8 0.1 0.4 1.0 1.2 0.9
Noisy workplace 0.6 0.7 3.6 0.4 0.9 0.6 0.7 0.0 0.3 -0.3 1.9 1.5 0.7 1.2 0.1 1.2 0.2 0.1 0.8 0.3 0.1 0.7 0.8 0.7 1.5 0.3 0.9 0.8 0.3 1.1 0.8 1.4 0.6 1.0 1.2 0.2 0.9 0.2 0.6 0.5 1.0 0.7
Qualifications: A levels/AS levels or equivalent 1.7 3.7 13.3 -0.7 -2.0 -0.7 -0.8 0.8 -1.8 1.1 -0.8 -0.9 -2.3 -0.9 -1.0 -0.8 -1.6 -0.6 -1.4 -0.4 -0.9 -0.8 -1.9 -1.3 -2.2 -0.8 -1.8 -1.8 -1.4 -2.3 -3.2 -3.4 -1.8 -3.0 -2.6 -3.1 -2.8 -2.8 -1.5 -2.9 -3.6 -1.8
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.3 4.1 -0.8 -1.7 -1.4 -1.0 1.1 0.3 1.2 0.3 -0.6 -0.2 -0.0 -1.1 -0.0 -1.3 -1.1 -0.5 -1.0 -1.2 -0.6 -0.9 -0.1 -0.8 -0.9 -1.3 -1.6 -1.1 -0.9 -1.6 -1.9 -1.4 -1.1 -1.1 -0.8 -1.7 -1.8 -0.6 -1.8 -2.0 -0.9
Mouth/teeth dental problems: Dentures 0.6 0.9 2.5 -1.3 -0.9 -0.5 -1.2 1.5 -1.6 1.2 -1.0 -0.4 -1.1 -0.8 -1.5 -0.9 -0.9 -1.1 -0.7 -1.3 -1.3 -1.1 -1.0 -1.0 -0.6 -1.3 -1.3 -0.9 -1.1 -0.4 -0.6 -0.3 -1.0 0.0 -0.3 -0.2 -0.6 -0.7 -0.7 -1.1 0.1 -1.0
Asthma 0.4 0.8 2.4 1.3 0.7 0.8 1.6 -1.1 -0.3 -1.2 1.1 1.2 0.2 1.0 1.1 1.2 0.8 1.1 0.2 1.0 1.2 1.0 0.9 0.7 -0.4 1.0 0.5 0.9 1.1 0.4 0.6 0.2 1.0 -0.2 0.5 0.6 0.8 0.7 0.4 0.8 -0.4 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 2.7 0.7 0.2 0.5 0.9 -0.6 -0.5 -0.3 1.7 0.3 -0.7 -0.1 0.5 0.2 -0.4 0.6 -0.6 1.2 0.5 0.7 0.4 -0.0 0.2 0.5 0.2 0.5 0.1 -0.0 0.2 0.8 0.7 0.1 0.3 -0.6 0.9 -0.2 0.2 0.5 0.1 0.1
Medication: Cholesterol lowering 7.4 11.5 29.4 4.8 3.0 3.0 5.4 -5.0 1.6 -3.5 4.1 4.9 2.3 2.6 4.7 3.4 3.4 4.6 1.7 4.7 4.6 4.6 3.6 2.6 -0.1 4.6 3.0 3.4 3.9 2.2 1.9 1.5 4.0 0.3 2.5 1.1 2.5 2.6 3.5 1.6 -0.2 3.6
Depression (self-reported) 0.4 0.5 3.5 0.8 0.2 0.4 1.0 -0.8 -0.1 -0.6 1.9 0.6 0.6 0.8 0.7 0.9 0.5 0.8 0.3 0.9 0.6 0.9 -0.1 0.4 0.0 0.8 0.5 0.3 0.6 -0.3 -1.1 -0.3 0.3 -0.7 -0.4 -1.6 -0.9 -0.5 -0.2 -0.3 -0.7 0.2
Medication: Lansoprazole 2.0 2.3 4.5 1.6 1.7 1.9 1.5 -1.2 -0.8 -1.3 1.1 2.0 0.8 1.5 1.3 1.5 1.5 1.7 1.6 1.8 1.4 1.8 1.8 1.5 1.8 1.5 2.1 1.6 1.4 1.6 0.8 1.5 1.7 1.4 1.7 1.3 2.0 1.1 1.3 0.5 0.8 1.7
Prospective memory result 0.4 0.4 3.1 -0.2 0.6 -0.1 -0.4 0.6 0.8 0.2 -0.2 -0.5 1.0 0.3 -0.4 0.1 0.2 -0.4 0.5 -0.4 -0.2 -0.3 0.4 0.4 1.0 -0.4 0.2 0.3 -0.1 1.0 1.2 1.1 0.0 0.9 0.7 1.8 1.1 0.4 0.1 0.8 1.2 0.1
Lung cancer (father) 1.1 1.3 3.4 1.0 1.1 1.0 0.9 -0.7 1.9 -0.9 1.4 1.0 1.5 1.6 0.9 1.5 1.0 0.9 1.2 0.8 0.8 1.1 1.3 1.2 1.4 0.9 1.4 1.1 0.8 1.3 1.2 1.3 1.0 1.1 1.3 1.0 1.2 0.9 1.3 0.8 0.9 1.2
Illnesses of mother 1.1 1.4 4.8 -1.3 -1.5 -1.6 -1.2 1.0 -0.6 1.2 -0.9 -2.2 -0.8 -1.9 -1.2 -1.8 -1.2 -1.2 -1.9 -1.2 -1.1 -1.6 -1.2 -1.3 -0.6 -1.3 -0.5 -1.3 -1.1 -1.2 -0.2 -0.6 -1.1 -0.7 -0.8 -0.3 -0.6 -0.4 -1.3 -0.2 -0.1 -1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 13.7 -1.4 0.1 0.7 -2.0 1.1 -1.0 0.7 -3.7 -1.6 -1.3 -0.7 -0.9 -1.3 -0.1 -1.2 0.5 -1.2 -1.0 -1.5 -0.4 -0.5 0.9 -1.2 -0.9 -0.1 -0.4 0.2 1.0 0.3 -0.7 0.3 -0.5 1.4 0.2 0.6 -0.4 0.6 1.4 -0.4
Pulse wave Arterial Stiffness index 0.7 0.9 2.4 -0.7 -0.7 -1.4 -0.6 0.3 -1.6 0.6 -0.6 -0.9 -1.4 -1.2 -0.5 -1.1 -0.5 -0.8 -1.2 -0.7 -0.5 -1.0 -0.9 -1.1 -1.5 -0.6 -0.7 -0.8 -0.4 -1.3 -0.6 -1.0 -0.7 -1.2 -1.2 -1.2 -0.9 -0.3 -0.9 -0.1 -0.8 -0.8
Impedance of arm (left) 0.1 0.4 4.8 0.2 -0.4 -0.8 -0.1 0.3 2.2 -0.5 -0.6 0.6 0.0 0.3 -0.1 0.1 -0.2 -0.0 0.1 0.1 -0.1 0.4 0.2 0.3 0.6 0.2 0.1 -0.0 -0.5 0.4 -0.9 1.1 0.4 1.7 1.1 -0.2 0.3 -0.5 -0.1 -0.6 1.0 0.2
Arm fat mass (right) 1.9 7.8 15.4 3.5 3.1 3.2 3.7 -3.6 -2.3 -2.6 3.3 3.6 1.8 1.0 3.4 1.6 2.5 3.5 0.7 3.8 3.4 2.9 2.7 1.7 1.1 3.0 3.4 3.3 3.4 1.8 2.6 3.0 3.6 0.7 2.2 1.8 3.9 2.6 2.5 2.9 1.1 2.6
Trunk predicted mass 0.3 1.5 24.3 0.0 1.5 0.7 0.4 -0.3 -4.9 -0.1 0.3 1.0 -1.4 -0.1 0.3 -0.1 0.5 -0.1 -0.1 0.4 0.3 -0.3 0.6 0.0 1.5 -0.1 0.8 1.2 0.7 0.4 2.3 1.6 0.9 -0.4 0.3 0.9 2.4 1.5 0.6 2.0 1.1 0.4
Standing height 0.2 1.9 14.0 -1.2 1.1 -0.5 -1.0 1.4 -3.7 0.3 -1.5 1.2 -2.6 0.7 -1.1 0.1 -0.3 -1.4 0.9 -0.9 -1.1 -1.0 0.2 -0.1 3.0 -1.1 0.2 0.9 -0.7 0.9 1.4 2.4 0.3 1.1 0.9 0.5 2.3 0.8 -0.1 0.8 2.5 0.1
Length of working week for main job 0.6 0.6 2.6 0.1 -0.6 -0.7 0.4 -0.4 -0.1 0.4 0.6 0.0 -0.9 -0.9 0.1 -0.6 -0.5 0.1 -1.5 0.5 0.2 -0.2 -0.6 -0.7 -1.3 0.1 -0.6 -0.5 -0.4 -1.3 -1.0 -1.3 -0.2 -1.6 -1.1 -1.3 -0.7 -0.7 -0.7 -0.8 -1.6 -0.7
Exposure to tobacco smoke at home 0.1 0.1 0.8 -0.1 -0.4 0.9 0.1 0.2 -0.9 0.2 0.3 -0.2 -0.0 -0.4 -0.2 -0.3 -0.1 -0.1 -0.5 -0.1 -0.0 -0.1 0.3 0.0 0.8 -0.1 0.3 -0.1 -0.1 0.3 0.7 0.1 -0.1 0.2 0.0 0.6 0.1 0.3 -0.0 0.4 0.2 0.0
Breastfed as a baby 0.2 0.2 2.5 0.1 0.1 0.5 -0.4 -0.2 1.3 -0.1 -1.6 -0.1 0.3 -0.7 0.1 -0.8 0.0 0.2 -0.2 0.1 0.1 -0.1 -0.3 -0.1 0.2 0.0 0.3 0.2 -0.3 -0.1 -0.3 0.7 0.2 0.3 0.1 -0.0 0.3 -0.0 0.2 -0.2 1.2 -0.1
Tense / ‘highly strung’ 0.4 0.6 4.8 -0.4 0.7 -1.6 -0.3 0.4 -0.0 -0.2 0.1 -0.5 0.5 0.9 -0.3 0.6 0.6 -0.6 0.8 -0.4 -0.3 -0.4 0.1 0.7 2.2 -0.2 -0.1 0.4 0.1 0.9 0.9 1.4 0.4 1.6 1.0 -1.0 0.4 0.5 0.1 1.1 1.8 0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.7 2.4 0.9 0.8 0.4 1.0 -1.0 1.2 -0.8 1.4 0.1 1.0 0.8 0.9 0.9 0.8 1.0 0.3 1.0 0.9 0.6 0.5 0.7 1.2 0.9 1.5 0.8 0.7 0.4 0.6 0.6 0.7 0.2 0.3 -0.6 0.0 0.6 1.0 0.6 0.4 0.7
Hair/balding pattern: Pattern 4 0.1 0.2 2.0 -0.1 -0.4 -1.4 0.1 -0.2 -0.5 0.2 0.4 0.3 -0.6 -0.4 0.0 -0.2 -0.3 -0.3 -0.8 -0.0 0.1 -0.1 -0.3 -0.4 -0.9 0.0 -0.1 -0.3 -0.1 -0.5 -0.1 -0.8 -0.3 -0.9 -0.6 -0.5 -0.6 -0.3 -0.1 -0.3 -0.8 -0.4
Birth weight of first child 1.3 2.4 11.5 1.6 1.4 2.2 2.3 -1.3 -0.4 -1.3 3.4 0.8 1.3 2.3 1.4 2.5 0.8 1.5 1.4 2.1 1.4 2.1 1.3 1.9 2.1 1.7 1.8 1.4 1.2 1.4 0.3 0.9 1.4 1.1 1.5 -1.2 0.5 0.1 0.9 0.5 0.3 1.2
Peak expiratory flow (PEF) 0.3 0.8 9.7 0.1 0.7 0.9 -0.7 -0.5 -1.4 -0.4 -3.1 -0.3 -0.8 -1.1 0.5 -1.4 0.5 0.2 -0.1 0.2 0.3 -0.5 0.1 -0.2 0.5 0.1 0.4 0.7 0.5 0.1 0.8 0.9 0.5 0.2 0.2 1.6 1.3 1.0 0.6 0.7 1.3 0.3
Pulse wave reflection index 2.2 2.8 6.5 -1.2 -1.8 -1.4 -1.2 1.1 -1.5 1.6 -0.2 -0.9 -2.1 -1.5 -1.3 -1.4 -1.7 -1.2 -1.7 -1.1 -1.3 -1.3 -1.6 -1.8 -2.0 -1.3 -1.0 -1.8 -1.6 -2.1 -2.0 -2.3 -1.7 -2.4 -2.1 -2.0 -2.1 -1.9 -1.6 -1.8 -2.5 -1.6
Ever highly irritable/argumentative for 2 days 0.5 0.5 1.8 -0.3 1.0 0.9 -0.4 0.4 1.0 0.0 -0.5 -0.3 1.0 0.7 -0.2 0.4 0.5 -0.4 1.3 -0.8 -0.2 -0.2 0.5 0.2 0.7 -0.3 0.2 0.4 0.2 1.0 1.2 1.3 0.4 1.1 0.6 0.7 1.3 1.1 -0.0 1.2 1.0 0.5
Loud music exposure frequency 0.6 0.6 3.6 0.4 0.9 1.4 0.2 -0.2 0.7 -0.4 1.0 0.7 0.8 -0.1 0.2 -0.1 0.1 0.4 0.0 0.5 0.2 0.4 0.5 -0.1 1.1 0.1 1.3 0.9 0.2 0.6 1.1 1.9 0.8 1.0 0.9 0.4 1.5 0.5 0.8 0.9 1.2 0.4
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 3.4 0.4 -0.6 -0.9 0.5 -0.2 0.6 -0.0 0.4 0.9 0.2 0.6 0.1 0.7 -0.4 0.5 0.1 0.5 0.0 0.6 -0.4 0.2 -0.9 0.3 0.2 -0.5 -0.2 -0.6 -1.7 -1.6 -0.3 -1.1 -0.6 -1.1 -1.2 -1.2 0.2 -1.9 -1.8 -0.2
Mouth/teeth dental problems: Bleeding gums 2.4 3.1 8.1 2.4 2.0 2.9 2.2 -2.2 -1.3 -2.1 0.8 1.0 0.7 1.7 2.2 1.9 1.9 2.3 1.5 2.4 2.3 2.0 1.9 1.8 1.0 2.2 1.4 1.9 2.0 1.4 1.3 0.8 1.9 0.4 1.2 1.0 1.5 1.4 1.7 1.4 0.2 1.9
Blood clot in the leg (DVT) 0.2 0.2 1.5 0.4 0.3 1.2 0.5 -0.2 0.6 -0.4 0.7 1.0 0.4 0.2 0.2 0.3 0.2 0.4 -0.1 0.2 0.3 0.3 0.2 -0.2 -0.2 0.2 0.5 0.5 0.3 0.2 0.1 0.8 0.5 0.2 0.2 -0.1 0.6 0.4 -0.2 0.7 0.5 0.3
Medication: Paracetamol 3.8 6.3 9.4 2.6 2.7 1.8 2.7 -2.4 2.5 -2.6 2.3 2.0 3.1 2.2 2.5 2.4 2.3 2.5 2.0 2.6 2.4 2.6 2.5 2.6 2.1 2.5 2.6 2.8 2.6 2.9 2.6 3.0 2.6 2.7 3.0 2.1 2.6 2.3 2.3 2.3 2.5 2.4
Headache pain in last month 0.2 0.3 2.0 -0.0 0.6 -0.6 -0.0 -0.1 -0.1 -0.3 0.0 -1.4 0.5 0.2 0.1 0.1 0.2 -0.2 0.3 -0.2 0.0 -0.3 -0.0 0.7 0.8 -0.0 -0.0 0.3 0.2 0.1 1.1 0.5 0.1 0.6 0.2 -0.4 0.2 0.6 0.2 1.4 1.1 0.2
Medication for cholesterol, blood pressure or diabetes 2.7 4.5 11.8 -3.1 -1.9 -1.9 -3.4 3.4 -1.3 2.3 -2.3 -3.0 -1.9 -1.2 -3.1 -1.8 -2.3 -3.1 -0.8 -3.0 -3.1 -2.8 -2.0 -1.5 0.8 -3.0 -2.0 -2.1 -2.6 -1.1 -1.0 -0.6 -2.5 0.2 -1.3 -0.8 -1.3 -1.8 -1.9 -0.8 0.6 -2.1
Glaucoma (self-reported) 0.2 0.2 0.7 0.4 -0.2 -0.2 0.7 -0.2 0.7 -0.1 0.8 0.2 0.1 0.7 0.2 0.9 -0.2 0.3 -0.0 0.5 0.2 0.8 0.2 0.4 -0.3 0.4 0.2 0.3 0.0 0.5 -0.1 0.5 0.3 0.4 0.8 -0.3 -0.1 -0.4 0.3 -0.4 0.7 0.2
Gout (self-reported) 0.2 0.3 3.3 0.3 -0.3 0.3 0.4 -0.4 -0.1 0.1 1.3 -0.0 -0.1 -0.4 0.3 -0.1 -0.1 0.1 -0.6 0.3 0.2 0.1 -0.1 -0.4 -1.4 0.1 -0.7 -0.4 0.1 -0.4 -0.2 -1.1 -0.2 -1.0 -0.6 -0.3 -0.5 -0.4 -0.4 0.1 -1.8 -0.3
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 1.5 0.2 -0.1 -0.4 0.3 -0.2 -0.5 -0.2 1.2 0.5 0.4 -0.4 0.1 -0.2 -0.1 0.2 -0.8 0.1 0.2 -0.1 0.5 -0.2 0.7 0.1 1.0 0.1 0.1 -0.2 0.6 0.4 0.3 0.1 -0.1 0.2 0.8 0.8 0.7 0.8 -0.0 0.4
Medication: Amlodipine 0.4 0.5 1.9 -0.5 -0.8 0.2 -0.4 0.5 -0.9 0.5 -0.0 -0.4 -0.8 -1.0 -0.6 -0.8 -0.8 -0.5 -1.1 -0.6 -0.5 -0.5 -0.8 -0.9 -1.4 -0.6 -0.8 -0.6 -0.7 -0.8 -0.8 -0.3 -0.5 -0.6 -0.6 -0.9 -0.2 -0.7 -1.0 -0.5 -0.8 -0.9
Medication: Ventolin 100micrograms inhaler 0.5 0.6 1.8 1.0 0.3 0.3 1.3 -1.1 -1.2 -1.0 0.3 1.1 -0.1 0.3 1.0 0.6 0.7 1.0 -0.5 1.0 1.1 0.7 1.0 0.5 -0.1 0.9 0.8 0.8 0.8 0.4 0.8 0.3 0.8 -0.2 0.7 1.1 0.9 0.9 0.5 0.6 0.1 0.7
Birth weight 0.5 1.0 4.0 1.3 0.8 1.4 1.7 -1.2 -2.0 -0.9 1.7 1.1 -0.4 1.3 1.0 1.6 0.7 1.4 0.6 1.5 1.1 1.2 0.4 0.4 0.3 1.1 0.7 0.5 0.6 -0.3 -0.8 -0.5 0.6 -1.1 -0.3 -1.4 -0.4 -0.3 0.4 -0.1 -1.0 0.6
Chronic bronchitis/emphysema (mother) 0.1 0.2 1.2 -0.1 0.3 0.2 -0.2 -0.0 0.9 -0.2 0.5 0.6 1.1 0.1 0.1 0.0 0.2 -0.1 0.3 -0.4 -0.1 -0.2 0.2 0.3 0.1 -0.2 0.3 0.1 0.4 0.1 0.6 0.1 -0.0 0.1 -0.2 0.6 0.3 0.7 -0.1 1.0 -0.2 0.3
High blood pressure (siblings) 0.3 0.4 2.3 0.0 -0.3 0.2 0.4 0.1 -0.5 0.6 0.6 1.5 -1.2 0.2 -0.1 0.4 -0.5 -0.2 -0.2 0.3 -0.1 0.6 -0.1 -0.7 -1.2 0.1 -0.5 -0.1 -0.2 -0.6 -1.0 -0.2 0.1 -1.0 -0.1 -1.2 -0.3 -1.0 -0.2 -1.5 -1.0 -0.3
Forced vital capacity (FVC), Best measure 0.4 1.3 16.4 -1.2 0.4 1.1 -1.8 1.1 -0.6 0.3 -4.1 -1.0 -1.1 -0.1 -0.7 -0.8 0.3 -0.9 1.0 -1.2 -0.7 -1.2 0.1 -0.0 1.2 -1.0 -0.7 0.3 -0.2 0.9 1.6 0.7 -0.5 0.8 0.0 2.4 0.7 1.2 0.1 0.7 2.0 0.0
Body fat percentage 2.1 8.5 14.3 3.6 3.2 2.9 3.7 -3.5 -0.3 -2.9 3.4 3.6 2.6 1.8 3.4 2.3 2.8 3.6 1.5 3.8 3.4 3.3 3.0 2.4 1.5 3.2 3.4 3.4 3.4 2.5 2.3 3.2 3.6 1.6 2.8 2.0 3.7 2.4 2.5 2.5 1.4 2.9
Leg fat percentage (right) 2.3 8.5 14.2 3.6 3.4 3.0 3.7 -3.5 -0.0 -2.8 3.4 3.3 2.7 2.2 3.4 2.6 3.0 3.6 2.1 3.8 3.4 3.4 3.0 2.5 1.6 3.3 3.2 3.3 3.4 2.6 2.3 2.9 3.4 1.6 2.8 1.9 3.2 2.4 2.7 2.3 1.2 3.0
Arm fat-free mass (right) 0.5 2.6 16.8 0.6 2.3 1.0 0.9 -0.9 -4.1 -0.7 0.5 1.5 -0.5 0.6 0.9 0.5 1.3 0.5 0.8 0.9 0.9 0.2 1.4 0.8 2.2 0.5 1.4 2.0 1.5 1.3 3.1 2.3 1.5 0.4 1.1 1.8 3.1 2.3 1.3 2.7 1.7 1.2
Exposure to tobacco smoke outside home 1.0 1.4 6.1 1.5 0.8 0.6 2.1 -1.5 -1.5 -1.3 2.2 2.5 0.3 0.3 1.3 0.8 1.0 1.5 -0.4 2.0 1.6 1.4 1.1 0.3 0.1 1.5 1.6 1.1 1.2 0.4 0.5 0.3 1.2 -0.4 0.6 -0.2 0.7 0.5 0.9 0.5 -0.4 0.9
Comparative body size at age 10 1.1 3.0 7.2 2.1 1.8 -0.1 2.4 -1.9 1.4 -1.7 2.6 1.8 2.7 1.4 1.9 1.7 1.2 2.0 1.2 2.1 1.9 2.2 1.7 2.1 1.2 1.9 1.9 1.9 1.9 1.7 1.4 1.6 1.9 1.1 1.7 1.2 1.9 1.0 1.4 1.3 0.7 1.6
Number of full brothers 0.2 0.3 2.2 -0.4 0.0 0.2 0.1 0.2 -1.5 0.1 1.0 1.4 -0.5 -0.3 -0.2 -0.2 -0.4 -0.3 -0.4 -0.4 -0.4 -0.2 0.1 -0.5 0.5 -0.3 1.0 0.2 -0.2 -0.3 0.4 0.6 0.2 -0.1 -0.2 -0.1 0.8 0.5 0.2 0.1 0.2 0.0
Worry too long after embarrassment 0.9 1.6 3.1 1.1 1.4 1.5 0.8 -0.9 1.3 -1.4 -0.1 0.5 1.4 1.3 1.0 1.2 1.5 1.3 1.6 1.1 1.2 1.2 1.3 1.5 1.2 1.1 0.6 1.3 1.2 1.4 1.2 1.2 1.0 1.3 1.1 1.6 0.9 1.1 1.3 1.6 1.8 1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 5.2 -1.1 -0.9 -1.2 -1.1 0.7 0.1 1.0 -0.1 -2.3 0.3 -1.4 -0.9 -1.3 -0.6 -1.0 -1.4 -1.2 -0.8 -1.6 -1.3 -0.9 -0.3 -1.2 -0.0 -1.0 -0.6 -1.2 0.0 -0.5 -1.1 -1.1 -1.5 -0.8 -1.0 -0.1 -0.7 0.7 0.0 -1.1
Wheeze or whistling in the chest in last year 1.6 2.9 5.5 1.9 1.9 1.8 2.3 -1.7 -1.6 -1.6 1.7 2.3 0.5 2.0 1.9 2.1 1.7 1.7 1.5 1.8 1.9 2.0 2.0 1.7 0.8 1.9 1.1 1.9 1.7 1.6 1.6 1.4 1.8 0.7 1.8 1.3 1.8 1.4 2.0 1.0 0.7 1.8
Number of children fathered 0.4 0.4 3.6 0.3 0.4 1.1 -0.3 -0.5 -0.7 -0.7 -1.9 -1.1 -0.4 -1.1 0.4 -1.2 0.8 0.5 -0.2 -0.1 0.6 -0.5 -0.2 -0.1 -0.1 0.1 -0.2 0.4 0.5 -0.3 0.1 0.0 0.2 -0.5 -0.5 1.2 0.5 0.9 -0.6 0.9 0.5 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 1.7 0.4 -0.0 1.0 0.1 -0.2 1.3 -0.2 -0.2 -0.4 1.1 0.6 0.4 0.5 0.3 0.5 0.6 0.3 0.4 0.5 0.6 0.9 0.4 0.5 0.0 0.2 0.4 0.8 0.3 -0.0 0.2 0.7 0.4 0.9 -0.0 0.2 0.4 0.1 -0.0 0.5
Age at first live birth 1.4 2.5 8.4 -0.9 -2.2 -0.3 -0.8 0.6 0.4 1.0 0.0 -0.5 -0.6 -0.8 -0.8 -0.6 -1.5 -0.9 -1.3 -0.8 -1.0 -0.4 -1.7 -1.2 -2.4 -0.6 -1.5 -1.7 -1.3 -1.9 -2.9 -2.5 -1.4 -2.0 -2.0 -2.6 -2.7 -2.2 -1.5 -2.4 -2.5 -1.4
Pulse wave peak to peak time 0.9 1.1 3.5 0.7 0.8 1.4 0.6 -0.3 1.3 -0.7 0.5 1.0 1.3 1.4 0.5 1.2 0.6 0.8 1.4 0.8 0.5 1.1 1.1 1.3 1.9 0.7 0.8 1.0 0.5 1.6 0.8 1.3 0.8 1.5 1.4 1.4 1.1 0.5 1.0 0.3 1.2 0.9
Health satisfaction 2.2 2.8 8.7 1.7 2.2 1.3 1.4 -1.8 -0.3 -1.8 0.4 0.8 1.3 0.6 1.8 0.6 2.2 1.6 1.0 1.5 1.9 1.0 1.8 1.3 1.5 1.5 1.3 2.1 2.2 1.4 2.4 1.9 1.9 1.3 1.3 1.7 2.3 2.4 1.5 3.0 1.8 1.9
Shortness of breath walking on level ground 0.6 0.7 2.4 -1.1 -0.1 -0.3 -0.6 1.2 -1.5 1.2 0.6 0.6 -1.5 -0.7 -1.1 -0.7 -0.9 -1.3 -0.7 -0.9 -1.0 -0.9 -0.6 -1.3 -0.5 -1.1 -1.1 -0.5 -0.8 -0.6 0.1 0.3 -0.5 -0.7 -0.3 -0.8 0.5 -0.4 -0.5 -0.2 -0.2 -0.9
Qualifications: College or University degree 0.7 2.3 8.6 -0.2 -1.7 -0.4 -1.0 0.2 0.1 0.4 -1.0 -0.9 -0.8 -1.7 -0.5 -1.6 -1.4 -0.2 -1.7 -0.2 -0.5 -0.9 -1.5 -0.9 -1.3 -0.4 -1.0 -1.5 -1.3 -2.4 -2.8 -2.8 -1.2 -2.2 -2.4 -2.1 -1.9 -2.2 -0.8 -1.8 -2.9 -1.1
Eye problems/disorders: None of the above 1.8 2.1 6.7 -1.4 -1.8 0.3 -1.7 0.9 -1.8 1.4 -2.4 -2.6 -1.1 -2.6 -1.1 -2.6 -1.3 -1.1 -1.7 -1.4 -1.2 -1.8 -1.6 -1.5 -1.4 -1.3 -1.5 -1.5 -1.0 -1.6 -0.7 -1.2 -1.2 -0.7 -1.6 -0.2 -1.0 -0.4 -1.1 -0.3 -0.2 -1.4
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.7 -0.3 -0.4 0.8 -0.2 0.4 0.0 0.2 -0.1 -0.7 -0.5 -0.7 -0.4 -0.6 -0.2 -0.3 -0.7 -0.5 -0.2 -0.5 -0.2 -0.4 -0.4 -0.6 -0.6 -0.4 -0.6 -0.6 0.2 -0.2 -0.3 -0.5 -0.6 -0.5 -0.0 -0.0 -0.7 0.8 -0.7 -0.4
Emphysema/chronic bronchitis 3.0 3.3 9.2 1.5 2.1 3.0 2.1 -1.2 0.1 -1.4 2.1 2.5 1.7 2.7 1.5 2.7 1.6 1.5 2.1 1.9 1.4 2.2 1.7 1.9 1.9 1.6 1.7 2.0 1.6 2.2 1.1 2.2 1.8 1.5 2.4 1.3 1.6 1.1 1.3 0.2 1.8 1.6
Medication for pain relief, constipation, heartburn 1.2 2.1 11.0 -1.8 -1.2 -0.7 -2.2 1.7 -0.5 1.4 -3.3 -1.8 -0.7 -0.5 -1.5 -1.0 -0.5 -1.5 0.2 -2.2 -1.5 -1.8 -1.3 -0.8 -1.1 -1.6 -2.0 -1.6 -1.1 -1.0 -1.2 -2.0 -1.7 -1.2 -1.7 0.1 -1.7 -0.5 -1.2 -1.3 -1.2 -1.0
Neck or shoulder pain in last month 4.1 5.9 18.2 1.7 3.2 0.8 1.5 -2.4 -0.8 -2.5 -0.7 0.9 1.1 0.7 2.3 0.5 3.0 1.6 1.5 1.5 2.4 1.0 2.1 1.6 2.4 1.9 2.2 3.1 2.9 2.2 3.9 3.8 2.8 2.3 2.2 2.5 3.5 3.9 2.4 3.8 4.3 2.3
Medication: Blood pressure 0.2 0.3 2.0 0.5 0.1 -0.1 0.8 -0.8 0.2 0.1 0.5 0.4 -0.1 -0.4 0.6 -0.1 -0.0 0.4 -0.3 0.6 0.5 0.5 -0.3 -0.2 -1.4 0.5 0.2 0.1 0.3 -0.5 -0.4 -0.7 0.3 -1.2 -0.2 -0.6 -0.2 -0.3 -0.1 -0.7 -1.2 -0.3
Angina (self-reported) 4.7 6.2 11.4 2.9 2.8 2.2 2.9 -3.2 0.2 -2.5 1.3 2.1 1.9 1.0 3.1 1.4 2.9 3.0 1.5 2.7 3.2 2.3 2.9 2.1 1.3 2.8 2.7 2.7 3.2 2.1 2.8 2.0 3.0 1.6 2.3 2.8 2.8 3.4 2.4 2.5 1.8 2.8
Migraine (self-reported) 0.3 0.4 1.1 0.7 0.4 1.0 0.7 -0.6 0.9 -1.0 0.4 0.5 1.0 0.5 0.6 0.6 0.4 0.8 0.1 0.7 0.6 0.5 0.3 0.5 0.6 0.6 0.7 0.5 0.3 0.3 0.5 0.6 0.5 0.6 0.5 -0.0 0.3 0.4 0.9 0.7 0.5 0.5
Medication: Ibuprofen 0.2 0.2 1.3 0.3 -0.1 0.2 0.3 -0.2 -0.8 0.1 0.8 0.2 -1.1 -0.7 0.1 -0.5 -0.8 0.2 -0.9 0.9 -0.0 0.2 -0.1 -0.5 -0.0 0.1 -0.3 0.1 -0.4 -0.5 -0.3 0.5 0.3 -0.2 -0.0 -0.9 0.6 -0.6 -0.2 -0.1 -0.2 -0.4
Medication: Allopurinol 0.2 0.3 2.8 0.7 0.2 1.0 0.9 -0.6 0.7 -0.3 1.7 0.3 0.7 0.3 0.6 0.6 0.3 0.5 -0.0 0.9 0.6 0.8 0.5 0.2 -0.4 0.6 -0.1 0.2 0.3 0.3 0.1 -0.3 0.3 -0.1 0.1 0.0 0.2 -0.1 0.1 0.1 -0.9 0.3
Medication: Omeprazole 0.1 0.2 1.2 -0.2 -0.2 -0.0 -0.4 0.2 0.3 0.5 0.1 -1.1 -0.3 -0.3 -0.2 -0.3 -0.4 -0.6 -0.1 -0.2 -0.2 -0.1 -0.1 -0.1 -0.0 -0.2 -0.8 -0.3 -0.2 -0.1 -0.1 0.2 -0.1 0.7 0.0 -1.0 -0.1 -0.3 -0.6 0.6 0.3 -0.2
Medication: Seretide 50 evohaler 0.6 0.7 3.8 0.8 0.7 1.1 1.5 -0.7 -0.1 -0.7 1.8 1.9 0.5 0.5 0.7 0.9 0.5 0.7 -0.1 0.8 0.7 0.9 0.9 0.6 -0.0 0.7 0.4 0.8 0.6 0.7 0.9 1.1 1.0 0.5 1.4 0.6 1.0 0.6 0.6 0.3 0.3 0.6
Mean time to correctly identify matches 2.3 4.4 9.0 -1.8 -2.6 0.4 -1.9 1.7 -0.3 2.0 -0.7 -2.0 -1.3 -2.0 -1.8 -1.9 -1.8 -1.6 -2.2 -2.0 -1.8 -1.8 -2.2 -2.4 -2.9 -1.9 -2.2 -2.3 -1.8 -2.5 -2.4 -2.9 -2.4 -2.6 -2.6 -1.8 -2.9 -2.0 -2.0 -2.2 -3.0 -2.2
Heart disease (mother) 0.3 0.3 2.6 0.4 0.3 0.6 0.6 -0.5 -1.5 -0.5 0.2 1.6 -0.5 -0.3 0.4 -0.1 0.5 0.5 -0.3 0.3 0.5 0.1 -0.1 -0.7 -1.1 0.4 0.3 0.3 0.4 -0.4 -0.0 -0.1 0.3 -0.9 -0.5 -0.6 0.0 0.3 0.3 -0.1 -0.6 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 5.0 6.0 11.2 2.3 3.0 1.0 1.9 -2.5 -0.1 -2.6 -1.0 1.1 1.9 1.8 2.7 1.5 3.2 2.4 2.6 1.9 2.7 1.7 2.7 2.4 2.4 2.5 1.7 2.8 2.9 2.6 3.1 2.5 2.7 2.3 2.6 2.7 3.0 3.3 3.0 3.0 2.9 2.8
Whole body fat mass 1.9 7.8 16.6 3.3 3.3 2.7 3.5 -3.3 -1.8 -2.6 3.0 3.7 1.9 1.5 3.2 1.9 2.6 3.2 1.2 3.5 3.1 2.9 2.8 2.0 1.6 2.8 3.3 3.4 3.2 2.3 2.7 3.4 3.5 1.2 2.6 2.1 4.1 2.6 2.4 2.7 1.5 2.7
Leg fat mass (right) 2.1 8.1 15.3 3.3 3.5 2.9 3.6 -3.4 -1.8 -2.6 3.1 3.6 1.9 1.6 3.3 2.1 2.8 3.4 1.5 3.6 3.2 3.0 2.9 2.2 1.7 2.9 3.3 3.4 3.3 2.4 2.9 3.2 3.5 1.2 2.6 2.2 3.9 2.7 2.8 2.7 1.3 2.8
Arm predicted mass (right) 0.5 2.7 14.4 0.8 2.4 1.0 1.1 -1.0 -3.8 -0.8 0.6 1.4 -0.4 0.7 1.1 0.6 1.4 0.7 0.9 1.1 1.0 0.4 1.5 0.9 2.3 0.6 1.4 2.0 1.6 1.4 3.0 2.4 1.6 0.6 1.2 1.8 3.1 2.3 1.2 2.7 1.8 1.3
Pulse rate, automated reading 0.9 2.9 12.4 -2.2 -0.6 -2.8 -3.1 2.2 0.6 1.7 -3.0 -3.5 -0.5 -1.6 -2.0 -2.3 -0.9 -2.5 -0.5 -2.8 -2.0 -2.7 -1.3 -1.2 -0.6 -2.3 -1.7 -1.5 -1.3 -0.6 0.7 -0.6 -1.6 0.2 -0.9 0.9 -0.1 -0.3 -0.7 0.3 0.0 -1.4
Alcohol intake frequency. 2.9 6.8 17.1 1.3 3.0 0.4 1.3 -0.8 3.7 -2.0 1.2 2.4 3.4 3.3 1.3 2.9 2.5 1.6 3.7 1.4 1.5 1.9 2.6 2.8 4.1 1.5 3.2 2.7 1.9 3.8 3.1 3.2 1.9 3.7 3.2 2.8 2.5 2.6 2.1 2.1 3.4 2.5
Comparative height size at age 10 0.3 1.6 12.9 -1.0 0.8 0.1 -0.8 1.2 -3.6 0.7 0.1 -0.1 -1.8 -0.3 -1.0 -0.6 -0.4 -1.2 0.0 -0.8 -0.9 -1.0 0.3 -0.5 2.3 -1.1 0.3 0.6 -0.5 0.8 1.6 2.5 0.5 1.4 0.8 0.7 2.7 0.9 -0.6 1.6 2.4 -0.1
Number of full sisters 0.9 1.1 3.6 0.8 1.3 0.2 0.8 -0.9 -0.6 -0.9 0.4 1.5 0.5 -0.0 0.9 0.1 1.2 0.6 0.5 0.7 1.0 0.5 1.2 0.6 0.9 0.7 0.6 1.1 1.2 0.9 1.9 1.5 1.2 0.8 0.9 1.3 1.7 1.6 1.1 1.7 1.3 1.0
Suffer from ‘nerves’ 0.3 0.4 1.4 -0.6 -0.9 -0.2 -0.5 0.6 0.6 0.3 -0.0 -1.1 -0.2 -0.3 -0.6 -0.3 -0.6 -0.6 -0.8 -0.7 -0.7 -0.7 -0.9 -0.5 -0.9 -0.6 -0.6 -0.6 -0.8 -0.7 -0.5 -0.4 -0.8 -0.6 -0.7 -1.1 -1.2 -0.6 -0.4 -0.2 0.1 -0.7
Overall health rating 3.9 8.5 20.6 2.6 3.6 2.1 2.7 -2.9 -2.1 -2.9 1.2 1.6 1.8 1.4 3.0 1.5 3.6 2.5 2.0 2.4 3.0 1.8 3.1 2.6 2.8 2.5 3.1 3.5 3.8 3.0 4.5 3.4 3.2 2.4 2.9 3.0 3.6 4.2 2.7 4.4 3.1 3.0
Chest pain or discomfort 4.2 6.0 10.4 2.8 3.2 1.7 2.9 -2.7 -0.8 -2.6 1.6 2.1 1.9 2.9 2.8 3.0 3.1 2.6 3.0 2.9 2.9 2.7 2.6 2.9 2.2 2.9 2.0 2.7 3.0 2.4 1.8 1.8 2.7 1.7 2.2 1.2 2.2 2.2 2.0 2.1 1.3 2.7
Had major operations 1.9 2.2 8.5 -1.5 -1.4 -2.9 -1.5 1.3 -1.4 1.4 -0.9 -1.7 -1.3 -1.8 -1.5 -1.9 -1.2 -1.6 -1.7 -1.8 -1.5 -1.8 -1.9 -1.6 -1.2 -1.5 -0.6 -1.5 -1.3 -1.8 -1.2 -1.0 -1.4 -1.1 -1.4 -1.5 -1.2 -1.1 -1.4 -1.0 -0.4 -1.6
Age at last live birth 0.5 0.8 5.2 0.2 -0.7 0.3 0.5 -0.6 -0.0 0.2 1.4 0.5 -0.1 0.1 0.3 0.3 -0.5 0.1 -0.6 0.5 0.1 0.5 -0.8 -0.4 -1.2 0.4 -0.1 -0.4 -0.3 -0.9 -1.6 -1.2 -0.2 -1.5 -1.0 -2.3 -1.4 -1.1 -0.5 -1.4 -1.7 -0.5
Family relationship satisfaction 0.5 0.6 6.5 0.8 0.8 2.6 0.7 -0.5 0.6 -0.8 0.2 0.4 0.8 0.7 0.6 0.7 0.6 1.0 0.8 1.1 0.7 0.9 0.6 0.7 0.6 0.7 0.1 0.9 0.5 0.7 0.5 0.8 0.6 0.2 0.6 0.3 0.4 0.2 0.7 0.4 0.6 0.7
Leg pain on walking 0.5 0.6 5.8 -0.7 0.2 -0.3 -0.7 0.3 -2.4 0.4 -1.0 0.3 -1.8 -1.1 -0.4 -1.1 -0.1 -0.8 -0.6 -0.7 -0.3 -1.0 -0.3 -1.3 -0.7 -0.7 -0.2 -0.2 -0.1 -0.8 0.4 -0.5 -0.3 -0.9 -1.0 -0.3 0.4 0.4 -0.5 0.5 -0.7 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 2.8 -1.4 -0.7 -1.6 -1.4 1.0 0.1 1.2 -1.1 -0.8 -0.2 -1.5 -1.1 -1.5 -0.5 -1.4 -1.1 -1.5 -1.1 -1.7 -1.0 -1.3 -0.6 -1.3 -0.8 -1.0 -0.8 -1.3 -0.2 -0.9 -1.1 -0.9 -1.1 0.0 -0.6 0.1 -1.3 0.1 0.0 -1.0
Commuting to job workplace: Car/motor vehicle 1.0 1.2 3.7 -1.1 0.0 -1.8 -1.0 0.7 -0.9 0.6 -1.3 -0.8 -0.5 -1.7 -0.7 -1.8 0.5 -0.9 -1.4 -1.5 -0.6 -1.9 -0.3 -1.1 0.3 -1.1 0.4 -0.2 -0.1 -0.4 1.6 0.8 -0.4 -0.0 -0.4 1.9 1.0 1.7 -0.4 1.7 1.7 -0.4
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 2.5 -0.3 0.0 0.0 -0.1 0.4 1.6 0.1 -0.5 0.2 0.1 1.2 -0.3 1.0 -0.0 -0.1 1.0 -0.2 -0.2 0.2 -0.2 0.2 -0.0 0.1 -0.8 -0.1 -0.2 0.5 -0.5 -0.4 -0.4 0.1 0.2 -0.7 -1.2 -0.5 -0.2 -1.2 0.2 -0.2
Medication: Aspirin 0.5 0.7 3.0 0.4 -0.3 -0.7 0.8 -0.7 -1.7 0.1 1.1 1.0 -0.7 -1.0 0.4 -0.6 -0.5 0.3 -1.4 0.7 0.4 0.1 -0.4 -0.7 -1.0 0.4 0.3 -0.2 -0.1 -1.2 -0.9 -1.0 0.1 -1.5 -0.7 -1.4 -0.3 -0.5 -0.7 -0.6 -1.6 -0.5
Supplements: Vitamin C 0.7 0.8 1.7 0.7 1.2 -0.0 0.5 -1.0 0.5 -0.9 0.0 1.2 1.1 0.2 0.9 0.2 1.2 0.5 0.6 0.5 0.8 0.5 0.8 0.7 0.8 0.8 1.0 1.1 1.0 0.7 1.2 1.2 1.0 0.5 0.8 1.0 1.3 1.3 1.1 0.9 1.2 1.0
Knee pain experienced in last month 2.4 3.8 9.2 1.6 2.7 0.2 1.4 -1.5 1.4 -1.6 0.9 1.3 1.7 1.6 1.7 1.5 2.1 1.2 2.1 1.3 1.5 1.4 2.1 2.1 2.0 1.4 1.1 2.2 2.1 2.4 3.0 2.4 2.0 2.0 2.2 2.5 3.0 2.2 2.1 2.6 2.0 1.9
Hypertension (Self-reported) 0.9 2.5 9.1 2.2 1.2 1.9 2.5 -1.9 1.3 -1.2 2.5 3.0 1.2 1.9 1.7 2.3 1.0 2.1 1.3 2.4 1.9 2.8 1.2 1.2 -0.7 2.1 1.2 1.2 1.1 0.8 -0.6 0.1 1.6 -0.3 1.0 -0.9 0.4 -0.4 1.2 -1.0 -1.5 1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 1.7 0.1 0.6 0.9 0.3 0.2 0.2 0.2 0.2 -0.3 0.0 1.3 0.1 1.2 0.3 -0.0 1.3 0.2 0.0 0.5 0.5 0.6 0.8 0.2 -0.1 0.1 0.1 0.7 0.4 0.6 0.3 1.0 1.0 -0.3 0.3 0.1 0.3 0.3 0.8 0.3
Illnesses of father: Heart disease 2.6 3.6 7.6 2.2 2.0 2.8 2.5 -2.0 -0.5 -1.8 1.5 1.4 0.9 2.3 2.1 2.4 1.6 2.2 2.0 2.7 2.2 2.5 1.8 2.1 2.0 2.4 2.2 2.2 1.8 1.7 0.7 1.8 2.2 1.4 1.9 -0.3 1.2 0.8 1.5 0.8 1.5 1.9
Illnesses of siblings: Diabetes 0.3 0.4 1.9 0.7 0.5 0.9 0.6 -0.9 -0.6 -0.2 -0.1 1.1 -0.3 -0.4 0.8 -0.2 0.6 0.5 -0.1 0.6 0.8 0.5 0.6 -0.4 -1.4 0.6 0.3 0.5 0.8 -0.2 0.5 -0.2 0.6 -0.6 -0.3 0.1 0.7 0.7 0.4 0.6 -0.7 0.4
Smoking status: Previous 0.8 1.2 4.0 1.6 1.1 1.4 1.2 -2.0 -0.5 -1.3 0.1 0.6 0.8 -0.4 1.7 -0.2 1.2 1.7 -0.0 1.4 1.7 0.9 0.8 0.4 -0.6 1.3 1.2 1.2 1.4 -0.0 0.8 0.3 1.3 -0.4 -0.0 0.6 1.3 1.6 0.8 1.4 0.2 1.0
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 2.9 -0.0 1.0 0.1 0.2 0.0 -0.9 -0.5 -0.2 1.7 -0.8 0.5 0.1 0.4 0.3 -0.3 0.7 0.0 0.1 0.1 0.6 0.4 1.3 0.1 0.3 0.9 0.1 0.7 1.4 1.5 0.8 0.9 0.9 0.5 1.6 1.1 0.6 1.0 1.5 0.5
Whole body fat-free mass 0.3 1.9 24.4 0.4 1.7 0.7 0.7 -0.7 -4.9 -0.3 0.4 1.3 -1.1 -0.3 0.7 -0.3 0.6 0.3 -0.2 0.8 0.6 -0.1 0.9 0.2 1.6 0.2 1.1 1.5 1.0 0.5 2.5 1.8 1.2 -0.3 0.5 1.2 2.8 1.8 0.8 2.3 1.0 0.7
Leg fat-free mass (right) 0.4 2.0 24.4 0.7 1.6 0.7 0.8 -1.1 -4.9 -0.5 0.2 1.4 -1.0 -1.1 0.9 -0.9 0.5 0.6 -0.7 1.1 0.8 -0.1 0.8 -0.1 1.2 0.3 1.4 1.5 1.1 0.0 2.2 1.8 1.4 -0.5 0.3 1.1 3.0 1.8 0.7 2.3 0.6 0.6
Arm fat percentage (left) 1.9 7.7 15.6 3.7 2.8 2.8 3.8 -3.8 -1.1 -2.7 3.6 3.4 2.4 0.9 3.5 1.5 2.5 3.7 0.4 4.0 3.5 3.1 2.8 1.9 0.8 3.2 3.5 3.1 3.3 1.8 2.2 2.9 3.6 0.9 2.2 1.7 3.6 2.3 2.4 2.6 0.8 2.6
Average weekly red wine intake 2.4 3.5 5.7 -1.5 -2.2 -2.3 -1.8 1.5 -0.3 1.8 -1.4 -1.9 -1.6 -2.1 -1.7 -2.0 -2.2 -1.9 -2.4 -1.7 -1.6 -1.7 -1.7 -1.9 -1.9 -1.6 -2.0 -2.1 -2.0 -2.1 -1.9 -2.0 -1.7 -1.7 -1.8 -2.0 -1.6 -2.2 -1.8 -1.7 -2.3 -1.8
Handedness (chirality/laterality): Left-handed 0.5 0.7 2.1 -1.2 -0.7 -0.4 -1.3 1.2 -1.2 1.1 -1.4 -0.3 -1.1 -0.6 -1.1 -0.9 -0.7 -1.2 -0.4 -1.1 -1.2 -1.1 -0.4 -0.8 0.5 -1.1 -0.8 -0.8 -1.0 -0.6 0.0 -0.1 -0.6 -0.1 -0.5 0.1 0.2 -0.1 -0.2 -0.3 -0.1 -0.5
Mood swings 3.1 5.6 11.0 2.8 2.5 2.5 2.7 -2.5 -0.7 -2.5 2.6 2.2 2.2 1.9 2.5 2.1 2.2 2.7 1.6 2.9 2.4 2.4 2.3 2.3 2.8 2.5 3.3 2.8 2.6 2.2 2.0 2.9 2.9 1.7 2.2 0.8 2.6 1.8 2.4 2.0 2.0 2.5
Loneliness, isolation 0.4 0.6 1.7 0.9 0.9 1.2 0.8 -0.9 0.4 -1.2 0.2 1.0 1.0 0.3 0.8 0.4 0.8 1.2 0.5 1.1 0.9 0.9 0.4 0.4 0.8 0.9 1.3 1.2 0.8 0.6 -0.2 0.8 0.8 0.1 0.5 0.3 0.5 0.5 0.1 -0.2 0.5 0.7
Long-standing illness, disability or infirmity 0.2 0.4 1.7 0.6 0.8 -0.8 0.6 -0.9 0.4 -0.3 0.6 0.1 1.0 -0.6 0.7 -0.4 0.7 0.3 -0.2 0.3 0.8 0.2 0.4 0.0 -0.3 0.5 0.5 0.5 1.0 0.3 1.1 0.5 0.6 0.2 0.4 0.7 0.8 1.0 0.4 1.3 0.3 0.4
Ever had bowel cancer screening 1.5 1.7 5.5 0.6 1.5 -0.2 0.5 -0.7 1.7 -0.8 0.1 -0.3 2.0 1.0 0.8 0.7 1.5 0.6 1.3 0.3 0.8 0.4 1.2 1.6 1.6 0.7 0.9 1.2 1.3 1.5 2.1 1.8 1.0 2.0 1.7 1.9 1.4 1.8 1.5 1.6 2.4 1.2
Diabetes diagnosed by doctor 2.1 3.4 6.0 2.3 2.4 1.1 2.0 -2.4 1.0 -1.8 1.0 2.1 2.1 1.7 2.4 1.8 2.4 2.2 2.1 2.1 2.3 2.0 2.0 2.1 0.7 2.1 1.5 1.9 2.5 1.5 1.6 0.9 2.0 0.6 1.4 1.8 1.7 1.9 1.8 1.6 0.0 2.0
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 5.8 0.2 0.3 -1.4 0.5 -0.5 -0.5 -0.1 1.2 2.4 -0.6 -0.5 0.3 -0.2 -0.3 -0.0 -0.7 0.3 0.1 0.1 0.3 -0.5 -0.1 0.1 0.2 0.4 0.3 -0.4 0.3 0.7 0.7 -0.6 0.2 -0.2 1.2 0.4 0.3 0.1 -0.2 0.2
Friendships satisfaction 0.3 0.3 4.0 0.6 0.8 2.0 0.1 -0.7 -0.1 -0.7 -1.0 0.0 -0.2 -0.1 0.6 -0.2 0.7 0.7 0.5 0.8 0.7 0.3 0.2 0.2 -0.0 0.6 -0.4 0.7 0.4 -0.2 -0.3 0.2 0.5 -0.4 -0.1 -0.4 0.4 0.2 0.0 0.4 0.1 0.4
Qualifications: nursing, teaching 2.9 4.5 14.1 -1.4 -2.3 -1.1 -1.1 1.6 -1.6 1.7 0.3 -0.1 -2.5 -0.6 -1.7 -0.4 -2.4 -1.4 -1.4 -1.1 -1.8 -1.0 -2.1 -1.7 -1.9 -1.4 -1.9 -2.2 -2.1 -2.1 -3.2 -3.4 -2.2 -2.7 -2.4 -3.3 -3.2 -3.4 -1.8 -3.2 -3.7 -2.0
Commuting to job workplace: Walk 1.7 1.9 3.9 -1.6 -1.7 -2.0 -1.4 1.4 0.1 1.4 -0.3 -1.1 -0.7 -0.9 -1.4 -1.0 -1.6 -1.8 -0.8 -1.7 -1.5 -1.2 -1.3 -1.0 -1.3 -1.3 -1.2 -1.7 -1.4 -1.2 -1.6 -1.6 -1.5 -0.9 -1.3 -1.3 -1.6 -1.4 -1.5 -1.6 -1.6 -1.4
Eye problems/disorders: Cataract 2.4 2.8 9.8 1.6 1.8 0.5 2.0 -1.3 2.2 -1.7 2.3 3.1 1.8 2.5 1.4 2.6 1.6 1.5 1.9 1.6 1.4 2.0 1.7 1.7 1.2 1.6 1.7 1.6 1.3 1.7 1.0 1.4 1.5 1.1 1.9 0.6 1.0 0.8 1.7 0.5 0.7 1.6
Mouth/teeth dental problems: Mouth ulcers 1.0 1.5 7.7 1.3 1.4 2.8 1.4 -1.0 -0.3 -1.5 0.6 0.7 0.3 2.1 1.1 2.0 1.3 1.7 1.8 1.6 1.2 1.6 1.0 1.2 0.8 1.2 0.8 1.3 1.1 1.4 0.4 0.9 0.9 1.0 1.1 0.8 0.3 0.4 0.3 1.0 1.0 1.1
Medication for cholesterol 9.7 14.8 25.1 -4.9 -4.0 -3.8 -4.8 4.6 -2.5 4.0 -3.0 -3.6 -3.6 -3.7 -4.6 -4.0 -4.0 -4.7 -3.7 -4.9 -4.7 -5.0 -4.4 -4.1 -2.0 -4.8 -4.1 -4.1 -4.1 -3.7 -2.3 -2.9 -4.3 -2.6 -3.5 -2.3 -3.2 -3.0 -3.5 -2.7 -1.6 -4.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.1 2.5 13.4 -1.9 -1.4 -3.7 -1.7 1.6 -1.3 1.7 -1.0 0.1 -1.3 -2.0 -1.7 -2.0 -1.4 -2.3 -1.9 -2.0 -1.7 -2.0 -1.7 -1.9 -1.0 -1.7 -1.4 -1.4 -1.4 -1.4 -0.8 -0.8 -1.4 -1.2 -1.0 -0.7 -0.9 -1.0 -0.9 -1.6 -0.4 -1.7
Back pain experienced in last month 1.1 1.5 8.3 -0.3 1.3 -0.2 -0.8 0.2 -0.2 -0.3 -1.6 -0.9 0.6 -0.1 0.0 -0.6 1.1 -0.4 1.0 -0.8 -0.0 -0.6 0.7 0.4 1.5 -0.4 -0.0 0.9 0.8 1.0 2.5 2.3 0.6 1.6 0.9 2.3 2.0 2.1 1.0 2.4 2.9 0.8
Mineral and other dietary supplements 0.5 0.7 4.2 -0.0 -0.6 -0.4 0.1 -0.6 -2.1 0.0 0.4 -1.6 -0.4 -1.6 0.3 -1.2 -0.1 0.0 -1.6 -0.0 0.2 -0.7 -0.6 -0.8 -0.9 -0.1 -0.0 -0.3 0.4 -1.1 0.5 -0.4 -0.1 -0.7 -1.2 -0.7 -0.5 0.5 -0.5 2.0 0.0 -0.4
Breast cancer (self-reported) 1.7 2.1 4.8 -1.4 -1.5 0.1 -1.2 1.4 -0.9 1.6 0.5 -0.6 -1.7 -1.6 -1.5 -1.4 -1.5 -1.3 -2.2 -1.2 -1.5 -1.5 -1.5 -2.0 -1.7 -1.6 -1.9 -1.3 -1.4 -1.6 -1.0 -0.9 -1.6 -1.9 -1.4 -0.9 -1.0 -1.2 -1.7 -1.2 -1.4 -1.8
Asthma (self-reported) 0.4 0.8 2.4 1.3 0.6 1.0 1.6 -1.1 -0.5 -1.2 1.1 1.4 0.1 1.1 1.1 1.3 0.7 1.1 0.2 1.1 1.2 1.1 0.9 0.8 -0.3 1.0 0.6 0.9 1.0 0.5 0.5 0.2 0.9 -0.2 0.6 0.7 0.7 0.6 0.4 0.6 -0.4 0.8
Osteoporosis (self-reported) 0.3 0.3 1.8 0.6 0.4 1.2 0.8 -0.3 -1.0 -0.5 0.7 1.4 -0.4 0.6 0.4 0.7 0.3 0.5 0.4 0.5 0.5 0.8 0.5 0.2 -0.1 0.6 0.2 0.4 -0.0 0.1 -0.1 0.6 0.6 0.2 0.4 -0.8 0.3 -0.1 0.9 -0.3 -0.2 0.4
Osteoarthritis (self-reported) 3.3 4.2 8.3 2.6 2.1 1.5 2.1 -2.6 -0.2 -2.4 0.5 1.8 1.8 0.8 2.5 0.9 2.3 2.8 1.0 2.6 2.6 2.0 2.3 1.7 1.4 2.4 2.9 2.4 2.6 1.9 1.8 1.6 2.3 1.1 1.8 2.9 2.5 2.1 2.2 1.7 1.1 2.3
Medication: Aspirin 0.6 0.8 2.7 0.0 -0.6 -0.7 0.1 -0.4 -1.2 0.4 0.1 0.3 -0.7 -1.4 0.1 -1.1 -0.7 0.0 -1.5 0.3 0.0 -0.4 -0.8 -0.9 -1.3 -0.0 0.1 -0.5 -0.4 -1.5 -1.2 -1.3 -0.2 -1.6 -1.1 -1.2 -0.7 -0.7 -1.0 -0.9 -1.6 -0.8
Medication: Gliclazide 1.2 1.4 2.9 1.3 1.3 0.4 1.3 -1.5 0.4 -1.2 0.6 0.7 1.5 0.6 1.5 0.7 1.4 1.2 0.8 1.2 1.4 1.1 1.3 1.2 0.7 1.3 0.9 1.3 1.7 1.1 1.6 1.2 1.4 1.0 1.2 1.0 1.3 1.4 1.1 1.7 1.0 1.2
Illnesses of father: None of the above (group 1) 0.6 0.7 1.7 -0.8 -0.9 -0.8 -1.3 1.0 -0.1 0.6 -0.9 -1.2 -0.3 -1.2 -1.0 -1.2 -0.8 -0.8 -1.0 -1.0 -1.0 -1.3 -0.8 -0.9 -0.3 -1.2 -0.5 -0.9 -1.0 -1.0 -0.5 -0.7 -0.9 -0.4 -1.0 -0.1 -0.2 -0.5 -0.8 0.2 -0.7 -0.8
Smoking status: Current 1.3 2.0 11.1 1.9 1.1 1.7 2.5 -1.6 -0.6 -1.4 3.3 2.1 0.8 1.0 1.4 1.6 0.7 1.6 0.3 1.9 1.6 1.9 1.4 0.7 0.6 1.6 1.3 1.4 1.0 0.7 0.6 1.5 1.7 0.5 1.1 -1.3 1.2 0.3 1.2 1.1 0.3 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.2 10.3 -2.0 -1.1 -0.6 -2.4 1.9 0.6 1.4 -3.2 -2.5 -1.4 -1.1 -1.8 -1.5 -1.1 -1.5 -0.1 -1.9 -1.7 -1.8 -1.6 -1.3 -0.6 -1.8 -1.8 -1.2 -1.3 -0.7 -0.9 -1.0 -1.9 -0.6 -1.5 0.1 -1.7 -1.0 -1.6 -0.9 0.1 -1.4
Whole body water mass 0.3 1.8 25.8 0.3 1.6 0.7 0.6 -0.6 -5.1 -0.2 0.4 1.2 -1.2 -0.5 0.6 -0.4 0.5 0.2 -0.3 0.7 0.5 -0.3 0.7 0.0 1.4 0.1 1.1 1.4 0.9 0.3 2.4 1.7 1.1 -0.5 0.3 1.0 2.7 1.7 0.7 2.2 0.9 0.6
Leg predicted mass (right) 0.4 2.0 25.0 0.7 1.6 0.7 0.8 -1.1 -5.0 -0.5 0.2 1.4 -1.0 -1.1 0.9 -0.9 0.6 0.6 -0.7 1.1 0.8 -0.2 0.8 -0.1 1.2 0.3 1.4 1.5 1.1 0.1 2.2 1.7 1.4 -0.6 0.3 1.1 3.0 1.8 0.7 2.3 0.6 0.6
Arm fat mass (left) 2.1 8.5 17.8 3.6 3.3 3.1 3.8 -3.8 -2.4 -2.7 3.2 3.6 1.9 0.9 3.5 1.5 2.8 3.5 0.7 3.9 3.5 2.9 2.9 1.8 1.2 3.1 3.5 3.4 3.5 1.9 2.9 3.2 3.7 0.8 2.3 2.2 4.2 2.9 2.5 3.2 1.3 2.8
Number of self-reported non-cancer illnesses 3.9 6.7 14.8 3.6 2.6 1.9 3.6 -3.9 2.0 -3.0 2.4 3.1 2.8 1.5 3.6 2.0 2.9 3.3 1.3 3.2 3.6 3.1 2.6 2.1 0.2 3.4 2.7 2.9 3.3 1.7 1.8 1.4 3.2 0.7 1.8 1.2 2.3 2.5 2.4 2.1 0.4 2.8
Average weekly champagne plus white wine intake 0.3 0.4 1.6 -0.3 -0.5 -0.4 0.1 0.1 0.4 0.4 0.9 1.2 -0.5 0.2 -0.2 0.4 -0.3 -0.3 -0.2 -0.1 -0.4 0.1 -0.7 -0.7 -1.0 -0.2 -1.1 -0.4 -0.2 -0.8 -1.1 -0.9 -0.5 -1.1 -0.7 -1.3 -1.0 -0.7 -0.8 -0.8 -0.8 -0.5
Miserableness 0.5 0.8 5.9 0.9 -0.3 1.3 1.1 -1.0 -2.4 -0.4 1.7 1.0 -0.6 -0.5 0.7 -0.0 -0.2 0.9 -1.3 1.3 0.6 0.7 -0.2 -0.6 -0.7 0.7 0.9 0.2 0.3 -0.8 -1.0 -0.0 0.5 -1.2 -0.5 -1.8 -0.2 -0.7 -0.1 -0.4 -1.0 0.0
Guilty feelings 0.6 1.0 3.3 0.7 0.8 1.7 0.2 -0.3 1.7 -0.9 -0.3 0.2 1.1 1.0 0.5 0.8 0.5 0.8 1.3 0.8 0.5 1.0 1.1 1.0 1.6 0.7 0.1 1.0 0.6 1.5 0.7 1.2 0.8 1.8 1.2 0.6 0.8 0.2 0.8 0.9 1.4 1.1
Wears glasses or contact lenses 0.2 0.3 2.2 0.7 0.1 0.5 0.4 -0.5 -0.5 -0.3 0.2 0.4 0.5 0.1 0.4 0.2 0.4 0.7 0.1 0.7 0.5 0.6 -0.0 0.3 -0.1 0.5 0.4 -0.1 0.3 -0.4 -1.5 -0.7 0.1 -0.7 -0.3 -0.8 -0.6 -0.7 -0.2 -0.7 -1.0 0.3
Ever taken oral contraceptive pill 3.0 3.4 6.1 -2.0 -2.0 -1.5 -1.5 1.8 -1.7 2.2 0.9 -0.6 -1.8 -1.6 -2.0 -1.4 -2.4 -2.2 -2.2 -1.9 -2.2 -1.7 -2.0 -2.2 -1.2 -2.0 -2.1 -2.1 -1.9 -2.2 -1.9 -1.2 -1.6 -1.4 -1.8 -2.5 -1.3 -1.9 -2.0 -1.2 -1.6 -2.0
Hearing aid user 0.2 0.2 1.6 0.2 -0.2 0.8 0.2 -0.3 -1.3 -0.2 -0.5 -0.0 -0.6 0.1 0.2 0.1 0.1 0.4 -0.1 0.5 0.2 0.3 -0.2 -0.1 -0.6 0.3 -0.2 0.0 0.1 -0.2 -0.7 -0.5 -0.1 -0.7 -0.3 0.0 -0.6 -0.5 -0.3 -0.9 -0.3 -0.1
Mother’s age at death 0.2 0.2 1.3 0.4 0.1 0.2 -0.1 -0.3 1.0 -0.4 -1.0 -1.2 0.4 0.3 0.3 0.1 0.4 0.7 0.9 0.5 0.4 0.5 0.2 0.7 0.1 0.4 0.0 0.3 0.4 0.5 -0.0 -0.3 -0.1 0.2 -0.0 0.7 -0.6 -0.1 0.6 -0.2 0.4 0.3
Financial situation satisfaction 0.8 1.0 4.8 1.4 0.9 2.2 1.4 -1.2 -0.4 -0.9 1.2 1.4 0.1 1.3 1.2 1.5 0.7 1.3 1.0 1.5 1.0 1.4 0.6 0.7 0.1 1.1 0.3 0.9 0.7 0.3 -0.3 0.5 1.1 -0.2 0.1 -0.9 0.5 0.1 0.1 1.0 -0.1 0.9
Tinnitus: Yes, now most or all of the time 0.4 0.5 2.0 0.6 0.3 1.2 0.1 -0.2 0.4 -0.5 -0.6 -1.0 0.7 0.2 0.3 0.0 0.3 0.4 0.3 0.5 0.4 0.5 0.7 0.8 1.1 0.5 0.7 0.6 0.4 0.8 0.4 1.2 0.8 1.4 1.0 -0.1 0.9 -0.0 0.5 0.4 1.1 0.7
Commuting to job workplace: Public transport 1.0 1.2 5.2 1.2 -0.3 1.2 1.5 -0.9 0.0 -0.6 2.1 1.0 -0.2 1.3 0.8 1.7 -0.4 1.0 0.4 1.5 0.7 1.6 0.1 0.7 -1.0 1.1 -0.3 0.0 0.3 -0.2 -1.4 -1.3 0.3 -0.8 -0.2 -2.3 -1.4 -1.5 0.5 -1.1 -2.2 0.3
Eye problems/disorders: Glaucoma 0.9 1.1 3.4 1.2 0.7 -0.1 1.2 -0.7 1.0 -0.9 0.8 1.4 0.7 1.9 0.8 1.8 0.5 1.2 1.1 1.2 0.8 1.5 1.1 1.2 0.7 1.1 0.7 1.0 0.7 1.3 0.4 1.4 1.1 1.1 1.5 0.6 0.9 0.1 1.3 -0.1 1.1 1.1
Medication: Blood pressure 4.1 7.9 19.4 3.7 2.5 3.6 3.8 -2.9 2.6 -2.7 3.6 3.6 2.8 3.7 3.0 4.0 2.4 3.7 3.0 3.9 3.2 4.4 2.9 2.9 1.1 3.5 2.7 2.6 2.3 2.6 0.4 1.4 2.7 1.4 2.4 0.3 1.3 0.7 2.5 0.3 -0.2 2.9
Pain type(s) experienced in last month: Hip pain 2.1 2.6 7.6 1.0 2.1 0.6 1.0 -0.9 0.8 -1.3 -0.2 1.3 0.8 0.8 1.2 0.7 1.6 0.9 1.5 0.9 1.2 1.0 1.8 1.0 1.6 1.1 1.6 1.8 1.5 2.0 2.7 2.5 1.7 2.2 2.1 2.0 2.6 2.1 1.9 2.1 2.4 1.5
Supplements: Fish oil (including cod liver oil) 0.5 0.6 5.9 -0.7 -0.0 -0.2 -1.0 1.3 2.4 0.7 -0.9 0.6 0.2 0.7 -1.0 0.2 -0.6 -0.8 1.0 -0.8 -0.8 -0.0 -0.2 -0.1 0.0 -0.6 -0.5 -0.4 -1.0 0.6 -0.9 -0.0 -0.6 0.4 0.6 0.2 -0.1 -1.0 -0.1 -2.1 -0.2 -0.3
High cholesterol (Self-reported) 15.4 27.2 49.2 6.7 4.6 5.1 7.0 -6.7 3.6 -5.7 3.8 6.5 4.0 4.4 6.7 5.1 5.9 6.7 3.3 6.3 6.7 6.6 6.1 4.5 1.3 6.7 5.1 5.5 6.2 4.5 3.7 3.6 6.0 2.6 4.5 4.1 4.3 5.0 5.5 3.0 2.2 6.0
Medication: Bendroflumethiazide 1.2 1.7 10.9 1.5 0.9 1.0 1.9 -1.3 3.3 -0.9 2.1 1.5 1.1 1.8 1.2 2.1 0.6 1.5 1.6 1.8 1.3 2.2 0.5 0.9 -0.8 1.5 1.0 0.6 0.4 0.3 -1.0 -0.5 0.7 -0.8 0.2 -1.3 -0.8 -0.6 0.3 -0.8 -1.5 0.6
Medication: Paracetamol 3.2 5.0 8.5 2.2 2.5 1.3 2.5 -2.0 2.6 -2.4 2.1 2.2 2.9 2.2 2.1 2.3 2.1 2.2 2.0 2.3 2.1 2.3 2.1 2.3 2.0 2.2 2.0 2.5 2.3 2.5 2.1 2.6 2.4 2.4 2.7 1.3 2.2 2.0 1.9 1.9 2.2 2.1
Medication: Lisinopril 0.4 0.6 3.3 0.2 -0.2 -0.7 0.3 -0.2 0.2 0.0 0.5 0.1 0.2 0.2 -0.0 0.4 -0.4 0.3 -0.0 0.4 -0.0 0.2 -0.8 0.3 -0.7 0.0 -0.1 -0.3 -0.2 -0.7 -1.4 -1.6 -0.6 -1.3 -0.9 -1.3 -1.4 -1.3 -1.0 -1.0 -1.8 -0.6
Medication: Atorvastatin 1.9 2.4 7.2 2.1 0.6 1.6 2.7 -2.2 2.0 -1.4 2.4 2.7 1.1 1.2 2.0 1.8 1.3 2.2 0.4 2.1 2.1 2.4 1.7 1.0 -0.5 2.3 1.3 1.1 1.5 0.6 0.2 0.2 1.5 -0.2 0.6 -0.1 0.1 0.8 1.8 0.2 -0.5 1.6
Illnesses of father: High blood pressure 0.9 1.1 4.4 -0.4 -1.0 -0.9 -0.5 0.1 -0.6 0.7 -1.3 -0.7 -1.5 -1.0 -0.3 -0.9 -0.7 -0.5 -0.9 -0.4 -0.3 -0.5 -1.0 -0.9 -2.1 -0.3 -1.7 -1.0 -0.6 -1.4 -1.4 -1.5 -0.7 -1.8 -1.4 -1.5 -1.2 -0.9 -1.0 -1.1 -1.6 -0.9
Alcohol drinker status: Never 0.3 0.4 4.9 -0.5 -0.3 -1.4 -0.5 0.8 2.2 0.5 0.3 -0.6 1.0 0.3 -0.6 0.2 -0.2 -0.6 0.3 -0.7 -0.4 -0.2 0.4 0.6 0.4 -0.4 0.4 -0.4 -0.6 0.7 0.3 0.1 -0.5 0.8 0.2 0.7 -0.1 0.0 -0.3 0.1 0.2 0.0
Ever smoked 2.4 4.2 11.8 2.8 2.4 2.2 2.4 -3.4 -0.6 -2.5 1.1 1.4 1.5 -0.1 3.0 0.3 2.4 2.6 0.4 2.4 3.0 1.7 2.0 0.9 -0.2 2.6 2.1 2.3 2.7 0.4 1.9 1.2 2.7 -0.1 0.5 0.6 2.6 2.7 2.0 2.9 0.7 2.2
Basal metabolic rate 0.5 2.6 21.9 1.0 2.1 1.1 1.3 -1.3 -4.7 -0.8 0.9 1.9 -0.6 -0.1 1.2 0.1 1.1 0.9 -0.0 1.4 1.1 0.4 1.3 0.5 1.6 0.7 1.7 1.9 1.5 0.8 2.7 2.2 1.8 -0.1 0.9 1.4 3.3 2.1 1.2 2.5 1.2 1.1
Leg fat percentage (left) 2.4 8.6 13.8 3.5 3.5 2.9 3.7 -3.5 -0.2 -2.9 3.4 3.2 2.6 2.3 3.5 2.6 3.1 3.5 2.1 3.7 3.4 3.3 3.0 2.6 1.8 3.3 3.3 3.4 3.5 2.6 2.4 3.0 3.5 1.6 2.8 1.8 3.3 2.5 2.6 2.5 1.4 3.0
Arm fat-free mass (left) 0.5 2.4 19.7 0.7 2.2 1.1 1.1 -1.0 -4.4 -0.7 0.7 1.6 -0.6 0.3 1.0 0.3 1.2 0.7 0.5 1.1 1.0 0.3 1.3 0.5 1.8 0.6 1.4 1.9 1.5 1.0 2.7 2.2 1.6 0.1 0.9 1.5 3.0 2.1 1.2 2.5 1.5 1.1
Number of operations (self-reported) 0.2 0.3 1.8 -0.3 0.3 -1.2 -0.2 0.1 -0.6 0.0 0.3 -0.6 -0.1 -0.7 -0.2 -0.7 0.1 -0.6 -0.6 -0.6 -0.1 -0.6 0.0 -0.4 0.2 -0.2 0.1 0.2 0.2 0.0 0.8 1.0 0.2 0.7 0.3 -0.4 0.9 0.7 -0.6 1.3 1.1 -0.0
Average weekly beer plus cider intake 0.2 0.2 2.3 0.2 -0.1 0.9 0.7 -0.0 -1.1 -0.2 1.5 1.0 0.2 -0.3 -0.0 -0.0 -0.0 0.2 -0.7 0.1 0.2 0.1 0.1 -0.4 -0.5 -0.1 1.1 0.1 0.0 -0.2 0.3 0.4 0.1 -0.6 -0.1 -0.1 0.3 0.2 -0.3 0.6 -0.4 -0.1
Irritability 1.6 2.7 9.0 1.3 1.9 1.1 1.5 -1.1 -1.1 -1.6 2.0 2.1 2.0 1.4 1.2 1.4 1.3 1.2 1.0 1.3 1.1 1.2 1.3 1.4 2.0 1.1 1.7 1.9 1.5 1.5 1.8 3.0 1.9 1.9 1.9 0.6 2.2 1.5 1.5 2.0 2.5 1.5
Risk taking 0.6 0.8 8.0 0.2 -0.2 0.2 0.6 -0.6 -2.8 0.0 0.3 0.5 -2.1 -1.2 0.3 -0.8 -0.3 0.1 -1.7 0.5 0.4 -0.1 -0.3 -1.5 -0.6 0.2 1.0 0.2 -0.1 -1.1 -0.2 0.9 0.8 -0.6 -0.3 -2.2 0.7 0.2 -0.5 0.5 0.2 -0.3
Ever had prostate specific antigen (PSA) test 3.0 3.4 7.9 -2.5 -1.7 -1.9 -2.8 2.1 0.2 2.4 -2.6 -1.8 -1.0 -2.3 -2.1 -2.6 -1.3 -2.6 -1.5 -2.8 -2.1 -2.4 -1.7 -1.9 -1.3 -2.2 -2.4 -1.9 -1.7 -1.6 -0.9 -1.2 -1.8 -1.0 -1.5 -0.1 -0.9 -0.7 -1.5 -1.5 -0.4 -1.8
Fractured/broken bones in last 5 years 0.2 0.3 2.4 0.2 0.5 0.3 0.6 -0.1 -1.5 -0.3 1.2 1.3 -1.0 0.7 0.1 0.8 0.1 0.0 0.2 0.3 0.1 0.3 0.0 -0.1 0.2 0.2 -0.1 0.3 -0.1 -0.3 -0.2 0.3 0.4 -0.3 -0.0 -1.5 0.4 -0.1 0.2 -0.1 -0.7 0.1
Age started oral contraceptive pill 0.3 0.3 1.7 0.5 -0.1 -0.0 0.7 -0.3 0.0 -0.3 0.8 0.3 0.2 0.8 0.2 0.8 0.2 0.7 0.4 0.6 0.3 0.7 -0.2 0.5 -0.5 0.5 0.0 -0.1 -0.0 0.2 -1.3 -0.8 -0.3 -0.6 -0.1 -0.3 -1.2 -0.9 -0.1 -1.2 -0.4 -0.0
Diastolic blood pressure, automated reading 2.2 6.7 16.6 -1.6 -2.9 -0.4 -1.4 1.6 -3.5 2.6 -0.8 -0.6 -4.1 -1.5 -1.8 -1.3 -2.7 -1.9 -2.5 -1.4 -2.1 -1.1 -2.3 -3.0 -4.1 -1.7 -3.1 -2.7 -2.5 -3.2 -3.5 -3.1 -2.0 -3.5 -2.6 -3.4 -2.4 -3.4 -1.7 -3.7 -4.0 -2.3
Ever depressed for a whole week 1.8 2.3 4.5 -1.5 -1.8 -0.7 -1.2 1.4 -1.7 1.8 0.8 -2.1 -0.9 -1.5 -1.5 -1.4 -1.8 -1.8 -1.9 -1.4 -1.6 -1.6 -1.7 -1.4 -1.0 -1.6 -1.3 -1.7 -1.6 -1.7 -1.2 -1.3 -1.6 -1.3 -1.6 -2.0 -1.4 -1.4 -1.5 -0.6 -1.1 -1.7
Unable to work because of sickness or disability 1.6 2.1 4.9 -1.5 -1.6 -1.7 -1.5 1.5 -0.8 1.1 -0.3 -0.3 -0.7 -2.1 -1.6 -2.0 -1.6 -1.5 -2.2 -1.7 -1.5 -2.0 -1.6 -1.8 -1.0 -1.8 -0.6 -1.3 -1.4 -1.6 -0.6 -1.2 -1.5 -1.6 -1.8 -0.6 -0.9 -1.1 -1.3 -0.7 -1.5 -1.7
Commuting to job workplace: Cycle 0.9 1.1 3.1 -0.8 -1.1 -0.3 -0.5 0.5 1.2 1.0 0.6 0.0 -0.2 -0.2 -0.7 -0.1 -1.4 -0.7 -0.9 -0.5 -0.8 -0.4 -1.2 -0.9 -1.1 -0.7 -0.5 -1.0 -1.2 -1.3 -1.5 -1.6 -1.1 -1.6 -1.5 -1.4 -1.7 -1.2 -0.8 -1.8 -1.6 -1.1
Myopia 0.5 0.8 2.0 1.0 1.0 0.3 0.9 -1.1 0.1 -0.9 0.7 1.4 1.1 0.5 1.1 0.5 0.7 0.9 0.5 1.2 1.0 0.9 0.7 1.0 1.1 1.0 0.6 1.0 1.1 0.6 0.6 1.1 1.2 0.5 0.8 -0.5 1.0 0.6 0.8 0.6 0.4 0.9
Vascular/heart problems diagnosed by doctor 0.7 1.9 7.2 -2.1 -1.0 -1.3 -2.2 1.9 -0.8 1.2 -2.0 -2.7 -1.2 -1.2 -1.7 -1.6 -1.0 -1.9 -0.8 -2.1 -1.8 -2.2 -1.2 -1.1 0.7 -1.9 -1.0 -1.1 -1.2 -0.5 0.2 0.0 -1.5 0.3 -0.8 0.4 -0.6 -0.1 -1.2 0.5 1.4 -1.2
Cholesterol lowering medication 9.0 13.3 23.3 4.6 3.5 3.5 4.5 -4.8 2.0 -3.8 1.2 3.7 2.6 2.8 4.8 3.2 4.5 4.8 2.8 4.5 4.8 4.6 4.2 3.4 0.9 4.8 3.2 4.0 4.5 3.2 2.4 2.7 4.3 2.0 3.1 3.4 3.3 3.6 3.8 2.2 2.1 4.2
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 0.7 -0.0 -0.2 0.4 -0.1 0.2 0.1 0.4 0.3 -0.3 -0.1 0.3 -0.1 0.2 -0.4 -0.3 0.1 0.0 -0.2 0.3 0.2 0.3 0.3 0.0 -0.4 -0.1 -0.1 0.2 -0.4 0.4 0.1 0.8 0.3 -0.6 0.0 -0.4 -0.4 0.1 0.5 0.0
Pain experienced in last month 2.7 4.5 20.8 -0.8 -2.7 0.5 -0.2 1.0 1.1 1.7 2.0 1.1 -0.2 -0.1 -1.2 0.3 -2.4 -0.6 -1.4 -0.2 -1.1 0.3 -1.8 -1.3 -2.7 -0.5 -1.6 -2.2 -2.1 -2.0 -4.5 -3.3 -1.7 -2.5 -2.0 -3.1 -3.3 -3.5 -1.8 -4.6 -3.9 -1.8
Supplements: Calcium 0.2 0.3 1.7 -0.2 -0.3 0.3 -0.3 0.3 -0.5 0.1 -0.4 0.2 -0.5 0.1 -0.3 -0.0 -0.3 0.0 -0.1 -0.1 -0.3 -0.2 -0.6 -0.1 -0.1 -0.2 0.0 -0.3 -0.7 -0.7 -1.3 -0.5 -0.4 -0.7 -0.4 -0.9 -0.6 -0.8 -0.3 -1.2 -0.7 -0.4
Basal cell carcinoma (self-reported) 1.4 1.6 4.6 1.4 1.2 1.2 1.2 -1.3 0.8 -1.3 1.0 1.8 2.1 1.3 1.3 1.4 1.3 1.8 1.3 1.6 1.3 1.6 1.3 1.5 1.3 1.3 1.2 1.2 1.5 1.3 0.4 0.6 1.1 0.6 0.9 1.9 1.0 0.9 1.4 0.0 0.2 1.4
Heart attack/myocardial infarction (self-reported) 0.3 0.4 7.4 0.2 -0.2 -0.1 0.7 -0.5 -2.7 0.1 0.9 0.8 -0.4 -0.6 0.3 -0.3 -0.3 0.2 -0.9 0.5 0.3 0.0 -0.3 -0.3 -0.6 0.1 0.4 -0.2 0.2 -0.7 -0.1 -0.5 0.1 -0.7 -0.3 -0.8 -0.3 0.2 -0.4 -0.2 -1.1 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 1.8 0.3 0.3 1.3 0.3 -0.0 0.6 -0.5 0.4 0.8 0.2 0.1 0.1 0.1 0.2 0.3 -0.1 0.0 0.1 0.1 0.3 -0.3 0.1 0.1 0.3 0.5 0.3 0.3 0.4 1.0 0.5 0.4 0.4 0.1 0.9 0.6 -0.1 0.9 0.9 0.3
Heart disease (siblings) 0.8 1.0 2.6 1.1 1.4 1.3 0.9 -1.1 -0.0 -1.3 -1.0 1.1 0.1 1.1 1.1 0.9 1.6 1.5 1.6 1.0 1.1 1.0 1.1 0.8 0.4 1.1 0.8 1.2 1.3 1.0 0.6 0.4 0.9 0.1 0.3 1.3 0.7 1.1 0.8 0.6 0.4 1.3
Alcohol drinker status: Previous 0.3 0.3 2.5 0.3 0.5 0.6 0.5 -0.0 0.0 -0.3 1.4 1.6 0.6 0.8 0.1 0.9 0.4 0.4 0.5 0.4 0.3 0.6 0.4 0.1 1.0 0.3 0.3 0.5 0.1 0.5 -0.1 0.6 0.3 0.2 0.4 -0.2 0.4 0.1 0.2 -0.2 0.2 0.4
Pack years of smoking 0.6 0.8 11.8 0.4 0.3 1.0 1.1 0.3 -0.7 0.0 3.4 1.4 -0.6 1.7 -0.1 1.9 -0.2 0.2 0.7 0.7 -0.0 1.1 0.6 0.4 1.2 0.2 0.1 0.2 -0.4 0.6 -0.0 0.4 0.3 0.3 0.7 -1.4 0.2 -1.1 0.6 -0.3 -0.8 0.3
Impedance of whole body 0.2 0.9 10.2 0.1 0.1 -0.6 -0.1 0.4 3.2 -0.8 -0.8 0.8 0.3 1.5 -0.1 1.2 0.3 -0.1 1.4 -0.2 -0.1 0.7 0.5 0.8 1.0 0.3 -0.2 0.3 -0.2 1.2 -0.5 1.3 0.4 2.3 1.6 -0.1 0.0 -0.2 0.1 -0.6 1.8 0.5
Leg fat mass (left) 2.2 8.5 15.5 3.4 3.6 3.0 3.6 -3.5 -1.8 -2.7 3.0 3.5 2.0 1.7 3.4 2.1 2.9 3.4 1.6 3.6 3.3 3.0 3.0 2.2 1.8 3.0 3.3 3.5 3.4 2.4 3.0 3.2 3.5 1.3 2.7 2.2 3.9 2.8 2.8 2.9 1.5 2.9
Arm predicted mass (left) 0.4 2.0 19.1 0.6 2.0 0.9 0.9 -0.9 -4.4 -0.6 0.4 1.1 -0.6 0.1 0.9 0.2 1.2 0.6 0.4 0.9 0.9 0.1 1.1 0.4 1.6 0.4 1.3 1.7 1.4 0.8 2.6 1.8 1.3 -0.1 0.7 1.5 2.7 2.1 1.0 2.4 1.3 1.0