Best TWAS P=4.96e-08 · Best GWAS P=7.57e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RASIP1 | 0.19 | 0.14 | lasso | 6 | 0.20 | 6.1e-15 | 5.3 | 5.5 | 5.0e-08 | 0.96 | 0.00 | 1.00 | TRUE |
| 2 | METSIM | Adipose | FUT1 | 0.04 | 0.01 | lasso | 6 | 0.02 | 6.9e-04 | -4.4 | -5.3 | 1.1e-07 | -0.66 | 0.02 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NTN5 | 0.02 | 0.01 | enet | 11 | 0.01 | 7.6e-04 | 5.1 | 5.3 | 1.1e-07 | 0.80 | 0.01 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | FUT2 | 0.09 | 0.12 | blup | 52 | 0.12 | 4.2e-14 | 5.1 | -5.3 | 1.0e-07 | -0.92 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FUT2 | 0.08 | 0.12 | lasso | 4 | 0.11 | 2.5e-05 | 5.3 | -5.3 | 9.9e-08 | -1.00 | 0.01 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FUT2 | 0.05 | 0.06 | blup | 52 | 0.06 | 8.6e-07 | 5.3 | -5.5 | 5.0e-08 | -0.93 | 0.01 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FUT2 | 0.14 | 0.16 | lasso | 8 | 0.14 | 4.9e-10 | 5.3 | -5.3 | 1.0e-07 | -0.99 | 0.01 | 0.99 | FALSE |