[Hub]/) : Traits : LDL Cholesterol : ←

chr20:39,270,768-40,683,594

Best TWAS P=1.16e-19 · Best GWAS P=3.36e-19 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZHX3	0.05	0.06	lasso	2	0.05	2.6e-06	9.0	-9.1	1.2e-19	-1.00	0.00	1.00	TRUE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZHX3	0.03	0.03	lasso	4	0.02	1.2e-05	8.3	-8.3	1.5e-16	-0.72	0.49	0.48	FALSE
3	GTEx	Artery Tibial	LPIN3	0.17	0.13	lasso	6	0.15	6.5e-12	6.8	8.1	8.1e-16	0.70	0.06	0.94	FALSE
9	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LPIN3	0.10	0.02	lasso	5	0.07	6.1e-04	6.7	7.2	8.6e-13	0.72	0.01	0.70	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	LPIN3	0.11	0.10	lasso	8	0.12	2.5e-15	6.1	7.1	1.2e-12	0.61	0.94	0.06	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	LPIN3	0.03	0.04	lasso	2	0.03	5.5e-04	6.8	7.0	2.0e-12	0.66	0.22	0.11	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PRO0628	0.05	0.01	lasso	2	0.02	4.5e-03	4.3	6.9	4.0e-12	0.66	0.01	0.51	FALSE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLCG1	0.03	0.00	blup	35	0.02	3.5e-03	8.8	-6.9	5.8e-12	-0.88	0.01	0.83	FALSE
2	GTEx	Artery Aorta	LPIN3	0.08	0.08	enet	4	0.08	5.4e-05	6.1	6.7	2.3e-11	0.62	0.30	0.61	FALSE
4	GTEx	Stomach	LPIN3	0.11	0.05	lasso	3	0.05	1.4e-03	6.1	6.4	1.7e-10	0.56	0.08	0.39	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	LPIN3	0.04	0.03	blup	45	0.04	9.3e-05	6.8	5.8	6.1e-09	0.42	0.10	0.12	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LPIN3	0.06	0.01	enet	27	0.03	5.4e-05	6.1	5.3	1.5e-07	0.49	0.44	0.46	FALSE