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chr8:10,265,712-11,891,593

Best TWAS P=2.69e-16 · Best GWAS P=5.2e-18 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
23	METSIM	Adipose	FAM167A	0.08	0.03	lasso	2	0.04	1.2e-06	8.6	8.2	2.7e-16	0.91	0.00	1.00	TRUE
22	METSIM	Adipose	BLK	0.03	0.02	lasso	4	0.02	1.6e-03	8.1	-7.8	6.8e-15	-0.91	0.00	1.00	TRUE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	BLK	0.03	0.01	lasso	3	0.01	2.1e-03	8.2	-7.1	1.8e-12	-0.91	0.01	0.99	TRUE
20	GTEx	Small Intestine Terminal Ileum	AF131215.9	0.14	0.11	enet	16	0.06	1.6e-02	-4.3	5.5	2.9e-08	0.47	0.19	0.12	TRUE
12	GTEx	Cells EBV-transformed lymphocytes	AF131215.2	0.20	0.10	enet	14	0.11	1.5e-04	-4.6	5.5	4.0e-08	0.53	0.82	0.01	TRUE
16	GTEx	Pancreas	AF131215.9	0.25	0.24	enet	14	0.22	1.0e-09	5.0	5.3	9.8e-08	0.50	1.00	0.00	TRUE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BLK	0.04	0.05	enet	6	0.05	7.3e-06	7.8	-8.1	4.1e-16	-0.95	0.00	1.00	FALSE
24	YFS	Blood	BLK	0.10	0.07	bslmm	604	0.08	3.6e-25	7.8	-7.7	1.5e-14	-0.91	0.01	0.99	FALSE
9	GTEx	Artery Coronary	AF131215.2	0.11	0.02	enet	27	0.05	6.5e-03	-4.7	7.1	1.2e-12	0.49	0.20	0.10	FALSE
27	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BLK	0.09	0.04	lasso	2	0.03	9.5e-03	7.8	-6.3	3.8e-10	-0.82	0.01	0.92	FALSE
3	GTEx	Adipose Visceral Omentum	AF131215.9	0.18	0.16	lasso	7	0.16	2.0e-08	5.6	5.7	1.3e-08	0.51	1.00	0.00	FALSE
1	GTEx	Adipose Subcutaneous	AF131215.2	0.24	0.15	lasso	7	0.14	3.5e-11	-5.6	5.6	2.5e-08	0.48	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	BLK	0.07	0.05	blup	115	0.03	2.4e-03	1.7	-5.5	3.0e-08	-0.71	0.25	0.31	FALSE
18	GTEx	Skin Sun Exposed Lower leg	AF131215.2	0.14	0.11	lasso	9	0.16	4.3e-13	-4.7	5.5	3.6e-08	0.50	1.00	0.00	FALSE
13	GTEx	Esophagus Mucosa	AF131215.2	0.15	0.14	enet	15	0.18	4.3e-12	-4.7	5.5	3.8e-08	0.58	1.00	0.00	FALSE
19	GTEx	Small Intestine Terminal Ileum	AF131215.2	0.14	0.07	lasso	3	0.07	1.1e-02	-4.9	5.5	4.1e-08	0.46	0.22	0.09	FALSE
4	GTEx	Adrenal Gland	AF131215.2	0.20	0.16	enet	12	0.13	2.2e-05	5.2	5.4	6.4e-08	0.53	0.96	0.03	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	AMAC1L2	0.10	0.03	enet	5	0.05	1.1e-05	3.5	-5.4	6.9e-08	-0.34	0.02	0.81	FALSE
2	GTEx	Adipose Visceral Omentum	AF131215.2	0.12	0.08	lasso	6	0.06	4.6e-04	5.6	5.4	7.3e-08	0.50	0.87	0.01	FALSE
7	GTEx	Artery Aorta	AF131215.2	0.09	0.09	lasso	7	0.08	2.0e-05	-5.6	5.3	9.3e-08	0.52	0.93	0.01	FALSE
15	GTEx	Pancreas	AF131215.2	0.16	0.16	enet	17	0.15	9.1e-07	-4.4	5.3	9.5e-08	0.52	0.99	0.00	FALSE
11	GTEx	Breast Mammary Tissue (Male)	AF131215.2	0.31	0.08	enet	23	0.03	5.9e-02	-5.6	5.3	1.1e-07	0.41	0.14	0.06	FALSE
8	GTEx	Artery Aorta	AF131215.9	0.13	0.05	lasso	6	0.07	1.3e-04	5.0	5.3	1.4e-07	0.51	0.94	0.01	FALSE
10	GTEx	Breast Mammary Tissue	AF131215.2	0.16	0.15	lasso	6	0.12	1.1e-06	-5.6	5.3	1.4e-07	0.55	0.92	0.01	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.2	0.16	0.11	enet	21	0.20	3.9e-11	-4.7	5.2	1.7e-07	0.52	1.00	0.00	FALSE
21	GTEx	Thyroid	AF131215.9	0.11	0.08	enet	16	0.17	4.7e-13	-4.4	5.2	1.9e-07	0.51	1.00	0.00	FALSE
6	GTEx	Artery Aorta	FDFT1	0.09	0.02	lasso	4	0.03	6.1e-03	6.9	5.2	2.3e-07	0.55	0.25	0.08	FALSE
14	GTEx	Nerve Tibial	AF131215.2	0.19	0.18	lasso	12	0.23	3.5e-16	-4.6	5.2	2.4e-07	0.51	1.00	0.00	FALSE
5	GTEx	Adrenal Gland	AF131215.9	0.18	0.16	lasso	10	0.18	3.5e-07	5.2	5.1	2.7e-07	0.53	0.95	0.02	FALSE