[Hub]/) : Traits : Lupus :

chr8:10,265,712-11,891,593

Best TWAS P=2.69e-16 · Best GWAS P=5.2e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous AF131215.2 0.24 0.15 lasso 7 0.14 3.5e-11 -5.6 5.6 2.5e-08 0.48 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum AF131215.2 0.12 0.08 lasso 6 0.06 4.6e-04 5.6 5.4 7.3e-08 0.50 0.87 0.01 FALSE
3 GTEx Adipose Visceral Omentum AF131215.9 0.18 0.16 lasso 7 0.16 2.0e-08 5.6 5.7 1.3e-08 0.51 1.00 0.00 FALSE
4 GTEx Adrenal Gland AF131215.2 0.20 0.16 enet 12 0.13 2.2e-05 5.2 5.4 6.4e-08 0.53 0.96 0.03 FALSE
5 GTEx Adrenal Gland AF131215.9 0.18 0.16 lasso 10 0.18 3.5e-07 5.2 5.1 2.7e-07 0.53 0.95 0.02 FALSE
6 GTEx Artery Aorta FDFT1 0.09 0.02 lasso 4 0.03 6.1e-03 6.9 5.2 2.3e-07 0.55 0.25 0.08 FALSE
7 GTEx Artery Aorta AF131215.2 0.09 0.09 lasso 7 0.08 2.0e-05 -5.6 5.3 9.3e-08 0.52 0.93 0.01 FALSE
8 GTEx Artery Aorta AF131215.9 0.13 0.05 lasso 6 0.07 1.3e-04 5.0 5.3 1.4e-07 0.51 0.94 0.01 FALSE
9 GTEx Artery Coronary AF131215.2 0.11 0.02 enet 27 0.05 6.5e-03 -4.7 7.1 1.2e-12 0.49 0.20 0.10 FALSE
10 GTEx Breast Mammary Tissue AF131215.2 0.16 0.15 lasso 6 0.12 1.1e-06 -5.6 5.3 1.4e-07 0.55 0.92 0.01 FALSE
11 GTEx Breast Mammary Tissue (Male) AF131215.2 0.31 0.08 enet 23 0.03 5.9e-02 -5.6 5.3 1.1e-07 0.41 0.14 0.06 FALSE
12 GTEx Cells EBV-transformed lymphocytes AF131215.2 0.20 0.10 enet 14 0.11 1.5e-04 -4.6 5.5 4.0e-08 0.53 0.82 0.01 TRUE
13 GTEx Esophagus Mucosa AF131215.2 0.15 0.14 enet 15 0.18 4.3e-12 -4.7 5.5 3.8e-08 0.58 1.00 0.00 FALSE
14 GTEx Nerve Tibial AF131215.2 0.19 0.18 lasso 12 0.23 3.5e-16 -4.6 5.2 2.4e-07 0.51 1.00 0.00 FALSE
15 GTEx Pancreas AF131215.2 0.16 0.16 enet 17 0.15 9.1e-07 -4.4 5.3 9.5e-08 0.52 0.99 0.00 FALSE
16 GTEx Pancreas AF131215.9 0.25 0.24 enet 14 0.22 1.0e-09 5.0 5.3 9.8e-08 0.50 1.00 0.00 TRUE
17 GTEx Skin Not Sun Exposed Suprapubic AF131215.2 0.16 0.11 enet 21 0.20 3.9e-11 -4.7 5.2 1.7e-07 0.52 1.00 0.00 FALSE
18 GTEx Skin Sun Exposed Lower leg AF131215.2 0.14 0.11 lasso 9 0.16 4.3e-13 -4.7 5.5 3.6e-08 0.50 1.00 0.00 FALSE
19 GTEx Small Intestine Terminal Ileum AF131215.2 0.14 0.07 lasso 3 0.07 1.1e-02 -4.9 5.5 4.1e-08 0.46 0.22 0.09 FALSE
20 GTEx Small Intestine Terminal Ileum AF131215.9 0.14 0.11 enet 16 0.06 1.6e-02 -4.3 5.5 2.9e-08 0.47 0.19 0.12 TRUE
21 GTEx Thyroid AF131215.9 0.11 0.08 enet 16 0.17 4.7e-13 -4.4 5.2 1.9e-07 0.51 1.00 0.00 FALSE
22 METSIM Adipose BLK 0.03 0.02 lasso 4 0.02 1.6e-03 8.1 -7.8 6.8e-15 -0.91 0.00 1.00 TRUE
23 METSIM Adipose FAM167A 0.08 0.03 lasso 2 0.04 1.2e-06 8.6 8.2 2.7e-16 0.91 0.00 1.00 TRUE
24 YFS Blood BLK 0.10 0.07 bslmm 604 0.08 3.6e-25 7.8 -7.7 1.5e-14 -0.91 0.01 0.99 FALSE
25 The Cancer Genome Atlas Breast Invasive Carcinoma BLK 0.03 0.01 lasso 3 0.01 2.1e-03 8.2 -7.1 1.8e-12 -0.91 0.01 0.99 TRUE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BLK 0.04 0.05 enet 6 0.05 7.3e-06 7.8 -8.1 4.1e-16 -0.95 0.00 1.00 FALSE
27 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma BLK 0.09 0.04 lasso 2 0.03 9.5e-03 7.8 -6.3 3.8e-10 -0.82 0.01 0.92 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma BLK 0.07 0.05 blup 115 0.03 2.4e-03 1.7 -5.5 3.0e-08 -0.71 0.25 0.31 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma AMAC1L2 0.10 0.03 enet 5 0.05 1.1e-05 3.5 -5.4 6.9e-08 -0.34 0.02 0.81 FALSE