[Hub]/) : Traits : Prostate Cancer :

chr3:127,074,386-128,821,807

Best TWAS P=8.71e-15 · Best GWAS P=6.94e-14 conditioned to 0.679

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EEFSEC 0.07 0.04 blup 496 0.04 1.2e-05 6.78 -6.7 3.0e-11 -0.72 0.04 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex RUVBL1 0.04 0.00 bslmm 434 0.03 3.6e-04 -0.78 -5.2 2.0e-07 -0.52 0.09 0.14 FALSE
3 GTEx Adipose Subcutaneous EEFSEC 0.07 0.03 enet 12 0.06 2.4e-05 7.78 -6.7 2.0e-11 -0.78 0.02 0.98 FALSE
4 GTEx Cells Transformed fibroblasts SEC61A1 0.13 0.18 lasso 2 0.17 1.0e-12 5.36 5.2 1.8e-07 0.66 1.00 0.00 FALSE
5 GTEx Cells Transformed fibroblasts EEFSEC 0.08 0.08 lasso 2 0.06 2.4e-05 7.62 -7.7 1.9e-14 -0.94 0.01 0.98 FALSE
6 GTEx Cells Transformed fibroblasts RUVBL1 0.07 0.04 lasso 3 0.02 2.5e-02 5.82 5.8 7.1e-09 0.52 0.72 0.20 FALSE
7 GTEx Esophagus Muscularis EEFSEC 0.07 0.08 lasso 5 0.07 4.4e-05 7.78 -7.8 8.7e-15 -0.95 0.01 0.98 TRUE
8 GTEx Muscle Skeletal EEFSEC 0.05 0.01 lasso 5 0.02 4.3e-03 4.50 -6.7 2.4e-11 -0.86 0.04 0.94 FALSE
9 GTEx Nerve Tibial EEFSEC 0.07 0.06 lasso 2 0.06 4.5e-05 7.76 -7.7 1.1e-14 -0.94 0.01 0.99 FALSE
10 GTEx Testis RUVBL1 0.31 0.30 lasso 12 0.30 1.2e-13 5.62 5.8 6.2e-09 0.54 0.98 0.02 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme EEFSEC 0.09 0.07 lasso 10 0.05 1.7e-02 5.72 -6.4 1.5e-10 -0.65 0.09 0.25 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma EEFSEC 0.07 0.05 blup 115 0.07 1.6e-08 7.79 -7.3 2.4e-13 -0.88 0.01 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma EEFSEC 0.08 0.03 blup 116 0.04 1.8e-04 5.72 -6.8 8.8e-12 -0.77 0.08 0.90 FALSE