[Hub]/) : Traits : Prostate Cancer : ← →

chr3:127,074,386-128,821,807

Best TWAS P=8.71e-15 · Best GWAS P=6.94e-14 conditioned to 0.679

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Esophagus Muscularis	EEFSEC	0.07	0.08	lasso	5	0.07	4.4e-05	7.78	-7.8	8.7e-15	-0.95	0.01	0.98	TRUE
9	GTEx	Nerve Tibial	EEFSEC	0.07	0.06	lasso	2	0.06	4.5e-05	7.76	-7.7	1.1e-14	-0.94	0.01	0.99	FALSE
5	GTEx	Cells Transformed fibroblasts	EEFSEC	0.08	0.08	lasso	2	0.06	2.4e-05	7.62	-7.7	1.9e-14	-0.94	0.01	0.98	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	EEFSEC	0.07	0.05	blup	115	0.07	1.6e-08	7.79	-7.3	2.4e-13	-0.88	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	EEFSEC	0.08	0.03	blup	116	0.04	1.8e-04	5.72	-6.8	8.8e-12	-0.77	0.08	0.90	FALSE
3	GTEx	Adipose Subcutaneous	EEFSEC	0.07	0.03	enet	12	0.06	2.4e-05	7.78	-6.7	2.0e-11	-0.78	0.02	0.98	FALSE
8	GTEx	Muscle Skeletal	EEFSEC	0.05	0.01	lasso	5	0.02	4.3e-03	4.50	-6.7	2.4e-11	-0.86	0.04	0.94	FALSE
1	CommonMind	Brain Pre-frontal Cortex	EEFSEC	0.07	0.04	blup	496	0.04	1.2e-05	6.78	-6.7	3.0e-11	-0.72	0.04	0.96	FALSE
11	The Cancer Genome Atlas	Glioblastoma Multiforme	EEFSEC	0.09	0.07	lasso	10	0.05	1.7e-02	5.72	-6.4	1.5e-10	-0.65	0.09	0.25	FALSE
10	GTEx	Testis	RUVBL1	0.31	0.30	lasso	12	0.30	1.2e-13	5.62	5.8	6.2e-09	0.54	0.98	0.02	FALSE
6	GTEx	Cells Transformed fibroblasts	RUVBL1	0.07	0.04	lasso	3	0.02	2.5e-02	5.82	5.8	7.1e-09	0.52	0.72	0.20	FALSE
4	GTEx	Cells Transformed fibroblasts	SEC61A1	0.13	0.18	lasso	2	0.17	1.0e-12	5.36	5.2	1.8e-07	0.66	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RUVBL1	0.04	0.00	bslmm	434	0.03	3.6e-04	-0.78	-5.2	2.0e-07	-0.52	0.09	0.14	FALSE