TWAS hub - HDHD3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0740	0.0280	1.7e-03	0.003	0.012	0.015	0.005	0.002	1.3e-01	1.2e-02	5.2e-03	7.8e-02	1.6e-01
2	GTEx	Artery Aorta	0.3460	0.0660	1.9e-08	0.120	NA	0.275	NA	0.256	4.0e-07	NA	1.7e-15	NA	2.5e-14
3	GTEx	Artery Coronary	0.2620	0.0890	1.6e-03	0.077	NA	0.060	NA	0.102	1.4e-03	NA	4.4e-03	NA	2.6e-04
4	GTEx	Artery Tibial	0.4954	0.0495	0.0e+00	0.252	NA	0.445	NA	0.423	9.4e-20	NA	3.5e-38	NA	8.6e-36
5	GTEx	Cells Transformed fibroblasts	0.1180	0.0450	4.3e-03	0.019	NA	0.028	NA	0.039	1.3e-02	NA	3.4e-03	NA	5.9e-04
6	GTEx	Esophagus Gastroesophageal Junction	0.2650	0.0780	8.6e-04	0.016	NA	0.090	NA	0.035	8.1e-02	NA	3.8e-04	NA	2.1e-02
7	GTEx	Esophagus Muscularis	0.2710	0.0650	5.4e-06	0.246	NA	0.262	NA	0.305	4.4e-15	NA	4.1e-16	NA	6.4e-19
8	GTEx	Heart Atrial Appendage	0.2060	0.0610	9.3e-05	0.148	NA	0.082	NA	0.005	3.5e-07	NA	1.6e-04	NA	1.8e-01
9	GTEx	Heart Left Ventricle	0.2394	0.0612	2.1e-05	0.178	NA	0.113	NA	0.162	9.2e-10	NA	1.3e-06	NA	5.4e-09
10	GTEx	Lung	0.2635	0.0635	6.7e-06	0.095	NA	0.125	NA	0.111	1.1e-07	NA	8.5e-10	NA	8.2e-09
11	GTEx	Muscle Skeletal	0.2044	0.0501	5.5e-07	0.152	NA	0.199	NA	0.194	1.1e-14	NA	3.2e-19	NA	9.3e-19
12	GTEx	Nerve Tibial	0.2591	0.0674	2.3e-05	0.141	NA	0.194	NA	0.194	3.5e-10	NA	9.1e-14	NA	9.3e-14
13	METSIM	Adipose	0.1441	0.0465	3.7e-04	0.009	0.019	0.038	0.036	0.047	1.5e-02	6.5e-04	1.7e-06	3.3e-06	1.4e-07
14	YFS	Blood	0.5192	0.0321	0.0e+00	0.234	0.262	0.310	0.308	0.304	2.1e-75	1.7e-85	4.8e-104	4.9e-103	1.7e-101
15	TCGA	Breast Invasive Carcinoma	0.0678	0.0250	2.1e-06	0.020	0.030	0.028	NA	0.027	4.2e-05	6.0e-07	1.8e-06	NA	2.1e-06
16	TCGA	Glioblastoma Multiforme	0.2130	0.0830	5.2e-03	0.064	0.044	0.051	NA	0.109	5.2e-03	1.8e-02	1.2e-02	NA	3.4e-04
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0608	0.0289	5.0e-03	-0.002	0.014	0.013	NA	0.004	5.5e-01	9.2e-03	1.3e-02	NA	1.1e-01
18	TCGA	Prostate Adenocarcinoma	0.1724	0.0524	1.3e-06	0.085	0.075	0.073	NA	0.086	3.4e-09	3.0e-08	4.8e-08	NA	2.7e-09
19	TCGA	Soft Tissue Sarcoma	0.1100	0.0500	4.2e-03	0.003	0.037	0.041	NA	0.034	2.0e-01	2.8e-03	1.9e-03	NA	4.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Stomach or abdominal pain in last month	4.7	5.8	14.5	-2.5	-2.6	-2.8	-2.4	-2.2	-2.6	-2.7	-0.5	-1.4	-2.3	-2.9	-2.2	-3.1	-3.8	-3.1	0.1	0.5	-3.2	-0.7
Townsend deprivation index at recruitment	3.4	4.8	12.7	-2.2	-1.5	-2.2	-2.1	-2.6	-2.4	-2.4	-0.8	-1.2	-2.9	-2.4	-3.1	-2.7	-3.6	-1.8	0.0	-0.0	-2.7	0.2
Serious illness, injury or assault of a close relative in last 2 years	3.0	3.4	8.4	1.9	2.0	1.2	2.2	2.5	1.3	1.4	2.9	2.6	2.0	1.6	2.0	1.4	2.0	0.8	2.0	-1.2	1.2	1.1
Illnesses of father: Heart disease	3.0	4.1	7.3	2.7	2.5	2.5	2.0	2.1	1.4	2.3	1.7	1.9	1.6	2.5	2.2	2.0	2.6	2.3	1.1	-0.2	2.0	1.0
Ever had hysterectomy (womb removed)	2.6	2.9	6.1	-1.8	-2.2	-1.7	-1.6	-2.1	-1.9	-1.7	-1.0	-0.6	-2.5	-2.0	-2.1	-2.1	-2.3	-1.4	-0.1	0.5	-1.7	-0.6
Eye problems/disorders: Cataract	2.6	3.0	5.5	2.3	2.2	1.8	2.3	1.8	1.7	1.9	1.6	1.9	1.8	1.7	1.8	1.9	1.3	1.2	1.8	0.1	1.3	1.0
Type 2 Diabetes (T2D) (2018)	2.5	4.6	9.1	-1.9	-2.8	-2.2	-2.7	-2.4	-3.0	-2.3	-0.5	-2.4	-3.0	-2.2	-1.9	-1.0	-2.8	-0.7	-1.2	1.3	-2.4	-1.4
Noisy workplace	2.5	3.1	6.7	-2.0	-1.8	-1.5	-2.3	-1.5	-1.7	-1.5	-2.2	-2.6	-1.5	-1.7	-1.9	-2.1	-1.1	-1.7	-2.0	1.0	-1.1	-1.3
Wears glasses or contact lenses	2.4	2.7	6.2	1.2	1.8	1.1	1.9	1.2	1.9	1.4	2.2	1.9	2.4	1.8	2.5	0.9	0.9	0.7	2.0	-1.4	0.6	1.8
Friendships satisfaction	2.3	2.8	8.0	1.1	0.9	2.6	1.1	0.7	2.0	2.1	0.1	0.4	1.9	2.5	1.0	1.9	1.7	2.5	-0.0	0.6	2.8	1.3
Eye problems/disorders: None of the above	2.2	2.6	5.1	-1.9	-1.1	-1.9	-1.5	-2.2	-1.9	-2.3	-1.0	-0.9	-1.7	-1.7	-1.7	-2.2	-1.5	-0.9	-0.2	-1.5	-2.2	0.2
Blood White Count	2.1	15.5	43.0	-4.9	-4.1	-3.2	-5.2	-3.5	-1.9	-3.0	-6.6	-5.5	-3.2	-4.0	-2.6	-0.5	-0.2	-2.2	-6.2	3.3	-1.2	-5.3
Coronary Artery Disease (CAD)	2.0	2.4	5.5	-1.3	-1.6	-2.3	-1.4	-1.4	-1.9	-2.3	-1.4	-0.9	-1.7	-1.9	-1.6	-2.0	-1.8	-1.1	-0.3	-1.2	0.0	-0.2
Illness, injury, bereavement, stress in last 2 years	2.0	2.4	5.5	-2.3	-1.8	-1.4	-2.0	-1.5	-1.3	-1.4	-2.2	-2.1	-1.2	-1.6	-1.2	-0.4	-1.0	-0.8	-2.1	1.3	-0.7	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.9	4.0	9.4	-3.1	-2.2	-2.5	-2.7	-2.0	-1.6	-2.1	-2.7	-1.7	-1.2	-2.6	-1.2	-0.1	-0.5	-1.6	-2.3	1.1	-1.2	-2.6
Commuting to job workplace: Walk	1.9	2.1	11.5	-1.3	-0.6	-1.1	-1.6	-1.1	-0.0	-1.0	-2.9	-1.4	-1.0	-1.2	-0.4	0.2	0.2	-1.5	-2.1	0.7	-0.3	-3.4
Loneliness, isolation	1.8	2.5	4.5	-1.9	-2.1	-1.7	-1.9	-2.1	-1.8	-1.7	-1.3	-1.9	-1.2	-1.7	-0.9	-2.0	-1.9	-1.4	-0.6	0.2	-1.7	0.2
Number of operations (self-reported)	1.8	2.6	6.1	-0.5	-1.8	-1.9	-1.2	-1.5	-1.9	-2.2	-0.1	-0.9	-2.1	-1.8	-1.4	-2.1	-2.5	-2.2	-0.1	-0.4	-2.1	-0.0
Diastolic blood pressure, automated reading	1.8	5.4	13.5	3.7	2.4	2.4	2.6	1.8	0.2	1.9	2.7	2.5	1.6	2.8	2.0	-0.1	1.1	3.0	2.2	-2.9	1.3	3.5
Mouth/teeth dental problems	1.7	2.5	5.6	-1.6	-2.0	-1.5	-1.7	-1.6	-2.4	-1.7	-0.6	-1.0	-2.3	-1.8	-2.2	-1.4	-1.8	-1.2	-0.6	0.5	-1.5	-1.1
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.8	7.3	-1.0	-1.7	-1.3	-1.8	-2.7	-2.0	-1.8	-1.2	-1.6	-2.3	-1.2	-1.5	-2.1	-2.2	-1.4	-0.9	0.8	-1.4	-1.5
Loud music exposure frequency	1.7	1.8	4.8	-1.8	-1.7	-0.9	-2.0	-1.3	0.2	-0.9	-2.2	-1.8	-1.0	-1.0	-1.5	0.2	-0.9	-0.7	-2.2	1.3	0.0	-0.6
Ever had prostate specific antigen (PSA) test	1.7	1.9	5.6	-1.0	-2.4	-1.5	-1.2	-1.7	-1.7	-1.8	-1.1	-1.4	-1.8	-1.7	-1.2	-0.6	-0.8	-1.2	-1.0	1.0	-1.5	0.4
Time employed in main current job	1.6	1.9	6.4	0.7	0.8	1.8	1.0	0.4	1.7	1.7	-0.2	0.4	1.2	1.5	1.2	2.2	2.5	1.0	-0.5	1.4	2.2	-0.1
Number of live births	1.6	2.2	6.5	-1.8	-1.6	-1.4	-1.6	-2.6	-1.1	-1.4	-1.5	-0.6	-1.5	-1.7	-1.8	-1.3	-1.8	-1.6	-0.2	0.8	-1.6	-0.2
Mouth/teeth dental problems: Dentures	1.6	2.7	7.3	2.2	2.0	2.7	1.5	0.6	1.7	1.8	0.3	0.2	1.5	2.6	1.5	0.8	1.4	1.5	0.4	1.6	2.3	1.5
Unable to work because of sickness or disability	1.6	2.1	5.4	-1.6	-1.2	-0.8	-1.5	-1.3	-1.5	-1.1	-0.6	-1.2	-1.9	-1.5	-2.3	-1.6	-1.8	-2.1	-0.8	1.6	-0.8	-0.6
Age when periods started (menarche)	1.5	3.5	8.9	-1.8	-2.5	-1.6	-2.5	-2.0	-1.3	-1.8	-3.0	-2.6	-1.7	-1.8	-1.9	-0.3	-0.2	-0.8	-2.7	1.8	-0.7	-1.6
Pulse rate	1.5	2.5	13.9	-2.2	-0.2	-0.9	-2.2	-1.9	-1.1	-1.3	-1.1	-1.2	-1.4	-1.0	-1.3	-0.6	-0.6	-1.5	-1.4	2.2	-0.3	-3.7
Age at first live birth	1.5	2.6	5.1	-2.1	-1.5	-1.8	-1.9	-2.2	-1.1	-1.8	-1.5	-1.3	-2.3	-2.2	-1.0	-0.6	-1.5	-1.6	-1.4	1.2	-1.2	-1.5
Back pain experienced in last month	1.5	2.3	6.4	1.8	2.5	2.0	2.0	1.7	1.7	1.6	1.6	0.6	1.5	2.4	0.9	-0.1	0.2	0.8	1.0	-0.0	1.4	0.9
Fractured/broken bones in last 5 years	1.5	1.9	5.0	0.7	1.2	2.1	0.7	1.1	2.2	2.1	-0.6	0.2	1.1	1.4	0.5	1.4	1.7	0.5	-1.0	1.9	2.2	-0.4
Systolic Blood Pressure	1.4	6.8	13.7	-2.5	-2.8	-2.9	-2.6	-2.7	-3.7	-2.6	-0.5	-0.9	-3.0	-3.0	-3.1	-3.5	-2.9	-2.4	-0.1	-2.0	-3.6	0.5
Worrier / anxious feelings	1.4	2.6	5.6	1.6	1.8	2.4	1.8	1.1	1.2	1.9	1.2	1.6	1.0	2.3	1.4	1.1	1.1	2.1	1.3	-0.1	1.9	1.6
Lung cancer (father)	1.4	1.6	7.8	0.1	-0.7	0.6	0.3	1.1	1.8	1.2	-0.6	-0.1	1.3	0.3	1.1	2.8	2.0	2.1	-1.0	-0.6	1.6	-0.4
Exposure to tobacco smoke at home	1.4	1.5	3.6	0.7	1.2	1.9	1.1	0.4	1.6	1.8	0.1	0.4	1.5	1.9	1.6	0.9	0.9	1.2	0.1	1.1	1.7	1.0
Pain all over the body in last month	1.3	1.4	7.3	0.8	1.5	1.2	1.4	1.3	-0.0	1.0	2.7	1.3	-0.0	0.7	1.1	-0.8	-1.1	0.4	1.8	-0.8	0.2	1.4
Blood clot in the leg (DVT)	1.3	1.7	6.5	-0.1	0.7	-0.6	0.0	0.4	-1.7	-0.6	2.5	1.3	-0.9	-0.5	-0.6	-1.9	-1.7	-1.0	2.3	-2.2	-1.2	-0.1
Arm fat-free mass (right)	1.3	6.7	15.4	-3.9	-2.8	-2.1	-3.7	-3.8	-2.6	-2.5	-2.3	-2.4	-2.5	-2.2	-3.1	-2.1	-2.0	-1.3	-2.3	0.4	-1.4	-3.1
Chest pain or discomfort	1.3	1.9	4.3	-1.9	-1.1	-1.0	-1.7	-2.1	-1.2	-1.2	-0.7	-1.2	-0.7	-1.4	-1.9	-1.6	-2.0	-1.5	-0.4	0.9	-1.3	-0.7
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	4.6	-0.4	0.4	-0.8	-0.3	0.0	-2.1	-0.9	2.1	0.8	-1.2	-0.8	-0.9	-2.0	-1.7	-1.2	1.8	-1.6	-1.2	-0.6
Arm predicted mass (left)	1.3	6.8	13.5	-3.6	-2.7	-2.1	-3.6	-3.7	-2.7	-2.5	-2.0	-2.3	-2.6	-2.3	-3.2	-2.5	-2.4	-1.6	-2.2	0.4	-1.6	-3.2
Blood Red Count	1.2	11.4	29.1	-2.3	-3.8	-3.8	-4.0	-1.5	-4.1	-3.4	-3.2	-3.8	-3.8	-4.1	-4.3	-2.4	-1.4	-2.3	-3.1	-1.0	-3.2	-5.4
Medication: Simvastatin	1.2	1.7	6.9	-0.0	-1.2	-0.8	-1.3	-0.5	-2.0	-1.2	0.7	-0.4	-2.6	-1.4	-2.4	-0.9	-2.1	-0.9	0.2	0.3	-1.2	-0.6
Age at last live birth	1.2	1.8	3.8	-1.3	-1.1	-1.5	-1.8	-1.8	-1.0	-1.5	-1.2	-1.0	-2.0	-1.9	-1.0	-1.1	-1.3	-1.2	-1.1	0.6	-1.2	-0.7
Guilty feelings	1.2	1.8	5.0	1.1	1.0	1.6	1.7	0.7	1.0	1.6	1.7	1.3	1.4	1.5	1.2	0.4	0.3	1.0	2.2	-1.2	0.8	2.0
Neuroticism (Nagel 2018)	1.1	2.7	4.8	1.4	2.1	2.1	2.2	1.1	1.6	1.8	1.6	1.4	1.9	2.0	1.8	1.4	0.5	1.3	1.8	-0.4	1.5	1.8
Neuroticism (2016)	1.1	1.6	5.5	0.8	1.3	1.1	1.7	0.2	1.1	1.1	0.6	1.5	2.3	1.5	1.8	0.5	1.3	0.6	1.6	-0.6	0.7	1.2
Prospective memory result	1.1	1.3	4.8	-1.8	-0.9	-1.1	-1.0	-2.2	-1.0	-1.4	0.2	-0.2	-0.2	-1.1	-0.7	-1.0	-1.6	-0.7	0.3	-1.3	-1.0	1.5
Arm predicted mass (right)	1.1	5.5	12.9	-3.6	-2.4	-1.8	-3.4	-3.4	-2.4	-2.2	-2.1	-2.3	-2.2	-2.0	-2.9	-1.8	-1.7	-1.0	-2.3	0.3	-1.1	-2.9
Leg fat-free mass (right)	1.1	5.9	14.3	-3.8	-2.3	-2.3	-3.5	-3.6	-2.4	-2.5	-1.8	-2.2	-2.2	-2.4	-2.7	-2.0	-2.1	-2.2	-2.1	0.4	-1.2	-2.2
Osteoarthritis (self-reported)	1.1	1.5	6.3	0.7	1.0	-0.1	-0.3	-0.4	-0.6	-0.3	1.9	0.3	-0.9	-0.7	-1.3	-2.1	-2.1	-0.9	1.4	-2.5	-1.1	0.7
Leg predicted mass (right)	1.1	5.7	14.0	-3.7	-2.2	-2.2	-3.5	-3.6	-2.4	-2.4	-1.7	-2.2	-2.2	-2.3	-2.7	-2.0	-2.1	-2.2	-2.0	0.4	-1.1	-2.1
Supplements: Fish oil (including cod liver oil)	1.1	1.4	4.0	-2.0	-0.4	-0.0	-0.7	-1.5	1.4	0.1	-2.0	-1.8	1.1	-0.4	0.2	1.6	0.6	0.9	-1.8	0.6	1.0	1.4
Medication: Bendroflumethiazide	1.1	1.6	5.7	-2.4	-1.9	-1.3	-1.8	-1.2	-1.7	-1.3	-0.5	-0.7	-1.3	-1.6	-1.7	-0.6	-0.4	-0.3	-0.4	-0.7	-1.1	0.5
Arm fat-free mass (left)	1.1	5.8	12.8	-3.5	-2.4	-2.0	-3.4	-3.6	-2.4	-2.3	-1.8	-2.1	-2.3	-2.1	-2.9	-2.2	-2.2	-1.4	-2.0	0.2	-1.4	-3.0
Irritability	1.1	1.9	5.0	0.7	1.0	1.0	1.7	1.7	1.3	1.5	1.3	1.0	2.2	1.0	2.1	1.8	1.1	1.6	0.9	-0.2	0.9	1.4
Alcohol drinker status: Previous	1.1	1.3	6.5	0.1	0.3	-0.2	0.5	-1.3	-1.0	-0.7	2.4	0.9	-0.1	-0.1	-0.2	-1.5	-1.5	-0.3	2.6	-1.0	-1.1	0.2
Rheumatoid Arthritis	1.0	1.4	3.3	1.4	1.8	1.6	1.6	1.1	0.8	1.4	1.5	1.4	0.8	1.7	0.9	0.2	0.1	0.4	1.5	-0.1	1.1	0.2
Hand grip strength (right)	1.0	2.7	5.7	-2.2	-1.0	-1.9	-2.4	-2.2	-0.6	-2.0	-2.1	-2.1	-1.0	-1.5	-1.0	-1.5	-2.0	-0.1	-1.8	-0.3	-1.6	-1.6
Qualifications: CSEs or equivalent	1.0	1.4	3.7	-0.4	-1.1	-1.6	-1.1	0.1	-1.9	-1.6	-1.1	-0.9	-1.6	-1.7	-0.9	-1.2	-0.3	-1.2	-1.2	0.1	-1.1	-0.8
Nervous feelings	1.0	1.8	5.3	1.2	1.9	2.3	1.4	0.8	0.8	1.8	1.1	1.4	0.9	1.8	0.8	0.3	-0.0	1.0	1.8	0.3	1.4	1.9
Trunk fat-free mass	1.0	5.5	12.7	-3.6	-2.4	-1.8	-3.3	-3.5	-2.2	-2.0	-2.5	-2.0	-2.0	-2.1	-2.8	-1.7	-1.8	-1.3	-2.2	0.7	-1.1	-3.1
Medication: Lansoprazole	1.0	1.2	4.4	1.4	0.4	2.1	0.8	0.4	0.4	1.7	-0.6	0.2	-0.2	1.9	-0.1	0.3	0.4	0.9	-0.2	1.8	1.7	-0.4
Pulse wave Arterial Stiffness index	1.0	1.2	4.5	-1.0	-1.4	-1.1	-1.1	-0.9	-1.3	-1.2	-0.5	-0.9	-0.5	-0.8	-1.3	-0.8	-1.0	-1.2	-0.8	0.3	-1.0	-2.1
Trunk predicted mass	1.0	5.7	13.1	-3.5	-2.5	-1.9	-3.3	-3.6	-2.3	-2.1	-2.5	-2.0	-2.1	-2.1	-2.8	-1.8	-1.9	-1.4	-2.1	0.6	-1.2	-3.1
Number of children fathered	1.0	1.1	2.8	1.3	0.7	1.4	1.1	0.6	1.5	1.7	0.4	0.8	0.8	1.4	1.4	-0.4	0.1	1.4	0.3	-0.8	0.5	1.5
Leg pain on walking	1.0	1.3	4.7	-0.0	-1.0	-0.8	-1.1	-1.2	-1.1	-1.3	-0.0	-0.9	-1.8	-0.8	-1.6	-1.6	-2.2	-0.8	-0.4	-0.1	-1.3	-0.1
Whole body fat-free mass	1.0	5.9	13.8	-3.7	-2.5	-2.0	-3.5	-3.6	-2.4	-2.2	-2.2	-2.2	-2.2	-2.2	-2.8	-1.9	-2.0	-1.6	-2.2	0.5	-1.2	-2.8
Illnesses of father: None of the above (group 1)	1.0	1.3	2.1	-0.8	-1.2	-1.2	-0.6	-1.0	-1.1	-1.4	-1.3	-1.1	-1.3	-1.0	-1.1	-1.1	-1.1	-1.3	-0.8	1.2	-1.0	-1.2
Whole body water mass	1.0	5.9	13.8	-3.7	-2.4	-1.9	-3.5	-3.6	-2.3	-2.2	-2.2	-2.2	-2.2	-2.2	-2.9	-1.8	-2.0	-1.6	-2.3	0.6	-1.1	-2.9
Basal metabolic rate	1.0	5.4	12.2	-3.2	-2.2	-2.0	-3.2	-3.5	-2.6	-2.3	-1.6	-1.9	-2.3	-2.0	-2.9	-2.4	-2.3	-1.7	-1.7	0.0	-1.4	-2.4
Age at First Birth	0.9	1.3	3.1	-1.8	-1.2	-1.5	-1.2	-1.5	-0.8	-1.2	0.2	-0.2	-0.6	-1.4	-1.1	-1.0	-1.7	-0.3	0.2	-1.3	-1.5	0.6
Bipolar Disorder (2011)	0.9	0.9	6.0	0.0	-1.9	0.0	0.0	0.0	-2.3	0.0	-0.2	0.0	-2.5	-1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.9	1.0	4.0	-0.6	-1.2	-0.8	-1.0	-1.1	0.1	-0.5	-2.0	-1.3	-0.4	-0.9	-1.1	-0.3	0.7	-0.9	-1.7	1.2	-0.5	-1.0
Leg fat-free mass (left)	0.9	4.7	10.5	-3.2	-2.0	-1.9	-3.1	-3.2	-2.3	-2.2	-1.4	-1.9	-2.1	-2.0	-2.5	-2.1	-2.0	-2.0	-1.8	0.3	-1.1	-1.9
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	6.4	0.3	0.1	-0.6	0.3	0.1	-0.4	-0.5	1.7	1.2	-0.9	-0.4	-0.2	0.0	-1.1	0.4	1.8	-2.5	-0.9	0.8
Leg predicted mass (left)	0.9	4.7	10.5	-3.2	-2.0	-2.0	-3.1	-3.2	-2.4	-2.2	-1.4	-1.9	-2.1	-2.0	-2.5	-2.1	-2.0	-2.0	-1.7	0.2	-1.2	-1.8
Heart attack	0.9	1.2	4.8	-0.2	-1.1	-1.2	-1.3	-1.0	-2.2	-1.2	-0.1	-0.5	-1.6	-1.4	-0.6	-1.7	-0.6	-0.5	-0.0	-0.9	-1.3	-0.0
Illnesses of siblings	0.9	1.3	5.1	-1.3	-0.8	-1.1	-0.8	-1.0	0.1	-0.8	-2.2	-2.2	0.8	-0.6	0.0	-0.0	0.8	-0.7	-1.9	1.3	-0.4	-1.2
Peak expiratory flow (PEF)	0.9	2.0	9.8	-1.9	-1.5	-1.2	-1.8	-0.9	-0.9	-0.8	-1.5	-0.5	-1.9	-1.7	-1.5	-0.7	-0.6	-0.9	-1.3	0.8	-0.6	-3.1
Medication: Amlodipine	0.9	1.3	4.7	-0.5	-0.8	-1.8	-1.1	-0.6	-1.5	-1.8	0.2	-0.6	-0.9	-1.6	-1.1	-0.9	-0.8	-2.2	-0.4	0.7	-1.4	-0.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.6	0.5	1.1	1.2	0.3	0.8	1.0	1.3	-0.0	-0.0	0.8	1.0	1.0	1.7	1.4	1.6	-0.8	0.4	1.9	-0.7
Number of self-reported non-cancer illnesses	0.9	1.5	4.5	-0.1	-0.3	-0.7	-0.4	-0.6	-1.6	-1.2	1.2	0.3	-1.5	-1.0	-2.1	-1.9	-1.7	-1.5	1.7	-0.8	-1.5	-0.5
Heart attack/myocardial infarction (self-reported)	0.9	1.2	5.2	-0.1	-0.9	-1.1	-1.2	-1.0	-2.3	-1.2	-0.1	-0.5	-1.8	-1.3	-0.6	-1.7	-0.6	-0.4	-0.0	-0.9	-1.3	-0.1
Schizophrenia vs Biploar Disorder	0.8	1.1	3.5	-0.6	-0.6	-1.5	-1.4	-1.1	-0.5	-1.4	-1.5	-0.9	-0.3	-1.7	-0.4	-0.2	-0.2	-1.3	-1.0	-0.4	0.0	-1.9
Neuroticism	0.8	2.0	4.5	1.0	2.1	2.0	1.8	0.9	1.3	1.8	1.2	1.1	1.5	1.9	1.4	1.3	0.3	1.4	1.4	0.5	1.5	1.3
Hearing difficulty/problems: Yes	0.8	1.2	7.8	-0.7	0.4	0.7	-0.1	-0.2	1.5	0.6	-1.8	-0.2	-0.1	0.3	0.8	1.1	1.2	-0.4	-0.9	2.8	1.4	-0.9
Taking other prescription medications	0.8	1.2	3.9	0.2	-0.7	-0.2	-0.0	-0.5	-1.7	-0.6	1.2	0.8	-1.4	-0.4	-1.9	-1.5	-2.0	-0.3	1.8	-0.5	-1.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	4.6	-1.9	-1.2	-1.5	-1.7	-0.6	-0.7	-1.1	-1.9	-1.8	-1.0	-1.5	-0.4	-0.4	-0.2	-1.7	-2.1	1.2	-0.8	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	6.3	-2.0	-0.9	-1.0	-1.7	-0.1	-0.1	-0.6	-2.2	-1.9	-0.7	-1.3	-0.3	0.0	0.2	-1.6	-2.5	2.0	-0.4	-1.7
Happiness	0.8	1.0	3.0	0.4	0.9	1.3	1.2	-0.0	1.0	0.8	1.5	0.6	1.7	1.4	0.4	-0.1	-0.2	0.8	1.4	-0.8	0.7	1.2
Standing height	0.8	8.3	18.9	-4.3	-3.6	-3.0	-4.0	-3.7	-2.2	-2.6	-3.1	-2.3	-2.4	-3.8	-3.0	-1.3	-2.4	-1.4	-1.8	-0.1	-2.2	-3.8
Breastfed as a baby	0.8	1.0	3.3	1.3	0.6	0.9	1.3	0.6	-0.1	0.9	1.8	1.2	1.1	1.5	0.4	0.5	0.7	0.3	1.7	-0.5	0.3	0.6
Leg fat percentage (right)	0.8	3.0	10.7	2.2	0.7	0.3	0.9	0.1	-1.9	-0.6	3.3	1.0	-1.5	1.1	-0.6	-3.2	-2.2	-0.4	2.5	-2.4	-1.5	0.8
Illnesses of siblings: Diabetes	0.8	0.9	4.9	-0.1	-0.0	0.2	0.2	-0.5	0.6	0.5	1.2	1.5	1.0	0.2	0.2	0.6	0.1	1.5	1.7	-2.2	0.1	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.5	0.0	0.8	0.0	1.5	0.6	1.6	0.2	0.9	0.6	0.9	0.7	1.2	-0.6	-0.5	-0.7	1.1	-1.4	-0.6	1.2
Medication: Aspirin	0.8	1.0	4.2	-0.3	-0.9	-0.3	-1.1	-0.7	-0.7	-0.6	-0.4	-0.7	-1.9	-0.7	-2.0	-0.9	-1.0	-0.9	-0.5	0.5	-0.4	-1.7
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.7	-0.6	-1.2	-1.6	-1.2	-0.4	-0.9	-1.3	-1.5	-0.9	-0.5	-1.6	-0.4	0.2	-0.1	-1.0	-0.7	0.3	-0.9	0.3
Risk taking	0.8	1.1	2.4	-1.3	-0.6	-1.3	-1.3	-0.6	-0.4	-0.8	-0.6	-1.2	-0.5	-1.4	-0.7	-0.6	-1.4	-1.5	-1.5	-0.1	-0.9	-1.5
Worry (Nagel 2018)	0.7	1.5	3.5	1.0	1.6	1.9	1.1	0.8	1.0	1.4	1.2	1.0	0.9	1.6	0.8	0.8	-0.1	1.6	1.2	0.0	1.4	1.7
HbA1C	0.7	0.8	2.8	0.5	0.6	1.7	0.4	1.1	0.9	1.5	0.8	0.3	0.0	0.6	-0.1	1.1	1.3	0.8	0.1	0.1	1.6	0.1
Trunk fat percentage	0.7	2.8	11.4	1.3	0.5	-0.1	0.3	-0.5	-1.9	-1.0	3.0	0.5	-1.6	0.5	-1.0	-3.4	-2.4	-0.5	2.0	-2.9	-1.4	1.2
Sitting height	0.7	5.2	14.2	-3.8	-3.0	-2.3	-2.9	-3.2	-2.0	-2.1	-2.1	-1.2	-2.0	-2.7	-2.4	-1.6	-2.1	-1.3	-0.9	-0.4	-2.0	-2.5
Trunk fat mass	0.7	2.9	13.2	0.1	-0.3	-0.6	-0.8	-1.5	-2.4	-1.5	2.0	-0.2	-2.2	-0.2	-1.8	-3.6	-2.9	-1.0	1.3	-2.3	-1.6	0.2
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.9	-0.8	-1.0	-1.6	-0.8	-0.1	-0.0	-1.3	-1.2	-1.0	0.1	-1.3	-0.1	-0.3	-0.1	-1.7	-1.2	-0.3	-1.4	-0.5
Neuroticism score	0.7	1.4	3.1	1.1	1.4	1.8	1.5	1.3	1.0	1.6	1.0	0.8	1.2	1.4	1.5	0.5	0.3	0.7	1.0	0.5	1.2	1.3
Hair/balding pattern: Pattern 3	0.7	1.0	3.4	0.1	1.1	0.5	0.5	0.3	1.8	0.5	-1.0	-0.4	1.6	0.7	1.8	0.8	1.4	0.0	-1.0	0.9	1.1	-0.1
Ever highly irritable/argumentative for 2 days	0.7	0.8	4.3	-0.7	-0.6	-0.2	-0.9	-0.7	-1.3	-0.1	-0.1	-0.7	-0.8	-0.4	-1.1	-1.8	-2.1	0.1	-0.7	-0.3	-0.8	1.0
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.6	0.2	-0.5	-0.5	-0.0	-0.4	-1.2	-0.9	1.3	0.3	-0.6	-0.6	-1.3	-1.6	-1.5	-0.8	1.1	-0.8	-1.3	0.3
Body fat percentage	0.7	2.8	11.4	1.6	0.6	-0.0	0.4	-0.3	-1.9	-1.0	3.0	0.5	-1.7	0.6	-0.8	-3.4	-2.4	-0.6	2.0	-2.7	-1.4	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	4.5	-1.5	-0.7	-0.2	-0.6	-0.7	-0.3	-0.2	-1.6	-1.1	-0.6	-0.5	-0.9	1.3	0.1	-0.4	-1.3	2.1	0.4	-0.7
Family relationship satisfaction	0.7	0.9	3.6	0.5	0.5	1.4	0.7	0.0	0.9	1.1	0.4	-0.2	1.4	1.6	0.8	0.1	0.6	1.9	-0.2	-0.8	1.2	0.5
Medication: Aspirin	0.7	1.0	4.8	-0.4	-0.9	-0.3	-1.1	-0.9	-1.1	-0.7	-0.1	-0.7	-1.8	-0.6	-2.2	-1.0	-1.0	-0.8	-0.2	0.4	-0.5	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.9	0.0	0.5	0.7	-0.1	-0.5	-0.6	0.5	-0.6	0.2	-1.3	0.5	-0.9	-1.3	-0.6	-1.1	-0.1	2.0	0.1	-1.7
Arm fat percentage (left)	0.7	2.6	11.8	1.3	0.6	-0.1	0.4	-0.5	-1.9	-1.0	2.8	0.4	-1.6	0.7	-0.8	-3.4	-2.5	-1.1	1.8	-2.3	-1.3	1.5
Long-standing illness, disability or infirmity	0.7	1.1	4.2	0.0	0.2	-0.4	-0.3	-0.9	-1.7	-1.1	1.0	0.1	-1.4	-0.3	-1.6	-1.3	-2.0	-1.1	1.5	0.3	-0.9	-0.5
Diabetes diagnosed by doctor	0.7	1.1	3.1	-1.2	-1.5	-0.5	-1.4	-1.4	-1.2	-0.9	0.2	-1.3	-1.8	-0.6	-0.7	-0.1	-1.5	0.8	-0.5	0.6	-0.7	-0.6
Mineral and other dietary supplements	0.7	0.9	6.0	1.0	-1.0	-0.5	-0.5	-0.1	-2.5	-0.8	0.0	0.4	-1.3	-0.4	-0.8	-0.8	0.1	-0.8	0.3	0.5	-0.9	-1.8
Pain type(s) experienced in last month: Hip pain	0.7	0.8	2.3	-1.1	-0.7	-0.6	-0.9	-0.8	-1.2	-0.9	-0.0	-1.1	-1.3	-0.5	-1.4	-0.8	-1.5	-0.8	-0.5	0.3	-0.6	-0.8
Medication: Paracetamol	0.7	1.1	4.7	0.6	-0.0	1.0	-0.4	0.2	0.1	0.6	-1.4	-1.4	-0.6	0.7	-0.4	0.4	0.9	-0.5	-1.9	1.4	1.4	-2.2
Leg fat percentage (left)	0.7	2.5	9.1	1.9	0.6	0.2	0.7	-0.2	-1.8	-0.8	3.0	0.7	-1.6	1.0	-0.7	-3.0	-2.2	-0.4	2.1	-2.3	-1.3	0.6
Schizophrenia (2018)	0.6	1.2	6.2	-0.0	0.7	0.2	-0.5	0.3	-0.9	-0.0	-0.0	-0.7	0.6	0.1	0.8	1.7	2.3	-0.8	-0.9	1.7	1.3	-2.5
Alzheimer’s Disease (in father)	0.6	0.6	4.0	-0.4	0.6	0.2	0.5	0.7	1.2	0.6	0.5	0.4	0.7	0.1	0.7	-0.6	-0.7	0.9	0.5	-1.2	-0.5	2.0
Body Mass Index (BMI) (2010)	0.6	0.8	1.8	1.2	1.1	1.0	0.9	0.4	0.5	0.9	1.3	1.0	0.6	0.9	0.2	0.2	-0.2	1.1	1.1	-1.0	0.3	1.1
Crohns Disease (2012)	0.6	0.9	5.4	-0.7	-0.5	-0.7	-0.5	-0.8	0.4	-0.3	-1.3	-1.5	0.8	-0.5	1.1	0.7	0.6	-0.9	-1.3	2.3	-0.2	-0.3
HDL Cholesterol	0.6	1.0	5.0	0.1	1.0	0.1	0.6	-0.2	-0.4	0.1	2.0	1.5	0.4	0.0	0.1	-0.8	-0.3	-0.9	2.2	-1.7	-0.4	0.5
Primary Biliary Cirrhosis	0.6	0.8	4.6	-0.5	0.3	0.9	-0.3	0.2	1.3	0.8	-0.6	-0.8	-0.1	0.5	0.1	0.8	0.7	0.6	-1.3	0.9	1.5	-2.1
Frequency of depressed mood in last 2 weeks	0.6	0.9	4.0	-1.4	-0.8	-0.9	-0.6	-2.0	-0.8	-1.0	0.0	-0.1	-0.6	-0.6	-0.4	-1.2	-1.4	-0.1	0.7	-0.1	-1.4	0.6
Ever used hormone-replacement therapy (HRT)	0.6	0.8	4.2	-0.9	-0.9	-0.6	-0.3	-0.7	-0.4	-0.3	0.5	0.4	-0.8	-0.8	-0.8	-0.9	-2.1	0.1	1.5	-0.5	-1.3	0.6
Systolic blood pressure, automated reading	0.6	1.8	6.6	0.8	-1.4	-0.3	-0.3	-0.9	-2.4	-0.8	0.6	-0.1	-1.4	-0.4	-1.3	-2.6	-1.6	0.2	0.7	-2.1	-1.6	1.8
Medication: Co-codamol	0.6	0.7	3.5	0.9	0.1	0.1	0.7	0.5	-1.1	0.1	1.9	1.1	-1.2	-0.0	-0.5	-0.6	-0.6	-0.3	1.5	-0.2	-0.6	-0.2
Current tobacco smoking	0.6	0.9	2.4	-1.0	-1.5	-1.5	-0.7	-0.4	-1.1	-1.5	-0.8	-0.8	-0.2	-1.4	-0.7	0.4	-0.6	-0.8	-0.4	0.5	-1.5	0.5
Chronic bronchitis/emphysema (father)	0.6	0.7	2.1	1.3	0.7	0.6	0.9	1.2	0.8	0.6	1.4	0.6	0.9	0.7	-0.1	0.4	0.3	0.1	0.8	-0.9	0.7	1.4
Fluid intelligence score	0.6	1.3	5.2	-1.1	-0.5	-1.1	-1.0	-0.9	-0.0	-0.9	-1.6	-0.9	-1.4	-1.2	-0.8	-0.4	-1.1	-0.4	-1.4	1.4	-1.0	-2.3
Weight	0.6	2.9	8.9	-1.4	-1.2	-1.2	-1.8	-2.5	-2.4	-1.8	0.3	-1.0	-2.0	-0.9	-2.1	-3.0	-2.6	-1.3	-0.0	-1.1	-1.5	-1.0
Arm fat percentage (right)	0.6	2.4	10.5	1.6	0.8	0.1	0.5	-0.2	-1.7	-0.7	2.9	0.6	-1.5	0.8	-0.8	-3.2	-2.3	-1.2	1.8	-2.0	-1.1	1.2
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	9.1	-1.6	-1.7	-1.3	-2.0	-1.2	-0.9	-0.9	-1.9	-0.7	-1.4	-1.7	-1.4	-0.6	-0.5	-0.7	-1.2	0.1	-0.7	-3.0
Depression (self-reported)	0.6	0.8	3.3	-0.2	1.2	0.7	0.5	-0.0	1.6	0.9	1.0	0.5	1.1	0.6	0.2	-0.2	-0.7	0.6	0.8	-1.2	0.3	1.8
Illnesses of mother	0.6	0.7	2.8	-0.4	0.1	-1.4	-0.3	0.2	-0.2	-1.4	-0.6	-1.0	0.4	-0.8	1.0	-0.5	-0.8	-1.7	-1.0	-0.1	-1.0	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	10.8	-1.5	-1.8	-1.3	-1.8	-1.2	-1.2	-1.0	-1.9	-0.6	-1.1	-1.5	-0.7	-0.1	0.2	-0.8	-1.4	0.6	-0.1	-3.3
Arm fat mass (right)	0.6	2.3	11.0	0.2	0.0	-0.4	-0.7	-1.5	-2.3	-1.3	2.0	-0.0	-1.9	0.1	-1.7	-3.3	-2.6	-1.2	1.1	-1.6	-1.3	0.1
Birth weight of first child	0.6	1.1	5.9	0.8	0.6	0.2	0.4	0.2	-0.8	0.2	1.9	1.5	-0.0	-0.1	-0.4	-1.0	-0.7	0.1	2.3	-2.4	-0.7	0.5
High blood pressure (siblings)	0.6	0.8	4.4	0.6	0.4	0.2	0.5	0.4	-0.7	-0.1	2.1	1.6	-0.2	0.0	0.2	-0.2	-0.5	-0.2	1.7	-1.3	-0.4	1.6
Forced vital capacity (FVC), Best measure	0.6	2.3	14.0	-1.8	-1.7	-1.3	-2.0	-0.9	-1.0	-1.0	-2.3	-1.0	-0.6	-1.6	-0.6	0.2	0.4	-0.9	-1.8	1.1	0.0	-3.7
Exposure to tobacco smoke outside home	0.6	0.8	3.3	-0.1	-0.3	0.9	-0.8	-0.5	0.3	1.0	-1.4	-1.8	0.6	0.5	-0.3	0.0	-0.2	0.7	-1.8	0.9	1.1	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.1	0.3	1.0	1.2	0.3	1.1	1.4	1.4	0.5	0.4	0.8	0.4	0.4	0.5	0.3	0.7	-0.3	1.3	1.1	-0.9
Migraine (self-reported)	0.6	0.7	2.9	-0.6	1.4	0.6	0.0	0.4	0.7	0.8	-0.7	-0.0	-0.2	0.5	0.8	0.3	0.7	0.0	-0.6	1.7	1.1	-1.7
Whole body fat mass	0.6	2.4	11.5	0.3	-0.2	-0.5	-0.7	-1.5	-2.2	-1.4	1.9	-0.2	-1.9	-0.0	-1.5	-3.4	-2.6	-0.9	1.2	-2.1	-1.4	0.3
Leg fat mass (right)	0.6	2.3	10.4	0.7	-0.1	-0.4	-0.4	-1.2	-2.4	-1.2	2.1	0.1	-2.0	0.1	-1.4	-3.2	-2.4	-1.0	1.3	-1.8	-1.4	-0.0
Comparative height size at age 10	0.6	3.1	8.3	-2.9	-1.9	-1.7	-2.3	-2.4	-0.9	-1.5	-1.4	-1.2	-1.3	-2.3	-2.0	-1.1	-1.9	-0.9	-0.7	-0.6	-1.4	-2.9
Number of full sisters	0.6	0.7	2.2	1.3	0.6	0.1	0.3	0.0	-1.1	-0.6	1.3	0.4	-1.5	-0.1	-0.9	-0.8	-1.1	-0.3	1.3	-0.5	-0.3	-0.3
Had major operations	0.6	0.7	2.5	0.1	-0.2	-0.5	-0.2	-0.5	-0.4	-1.0	0.5	-0.3	-0.6	-0.4	-0.5	-1.6	-1.3	-1.6	0.3	-0.3	-1.1	1.2
Asthma (self-reported)	0.6	1.1	3.5	-0.5	-1.1	-0.2	-0.6	-0.8	-1.0	-0.8	-1.0	-1.6	-1.0	-0.3	-1.2	-1.9	-1.8	-1.1	-0.7	1.4	-0.6	0.5
Mother’s age at death	0.6	0.7	2.9	-0.6	0.5	0.1	0.3	0.1	0.5	0.5	0.9	1.2	1.7	0.2	1.3	0.9	0.8	1.5	0.7	-1.2	0.4	0.6
Age started oral contraceptive pill	0.6	0.7	1.6	-0.9	-0.4	-1.0	-1.0	-0.6	-0.9	-0.7	0.8	-0.1	-1.0	-1.1	-0.4	-1.2	-0.7	-0.9	0.4	-1.1	-1.2	-0.9
Commuting to job workplace: Cycle	0.6	0.8	3.4	0.5	0.4	-0.3	1.0	-0.2	0.4	-0.0	1.1	1.2	1.0	0.5	0.6	-0.1	0.2	-0.3	1.4	-1.9	-0.5	1.6
Cholesterol lowering medication	0.6	0.8	3.1	0.0	-0.8	-0.7	-1.0	-0.5	-0.3	-0.6	-0.5	-0.7	-1.7	-1.1	-1.2	-0.6	-1.0	-1.1	-0.7	0.6	-0.8	-1.8
Alzheimer’s Disease (including proxy)	0.5	0.8	6.0	0.5	1.0	0.5	0.7	0.2	1.3	0.5	0.5	0.9	0.5	0.6	0.8	-1.1	-0.8	0.3	0.6	-0.7	-0.2	2.5
Lupus	0.5	0.8	3.2	0.5	0.3	-1.0	0.4	0.9	1.0	-0.4	0.5	0.8	0.5	-0.6	1.1	1.1	0.7	0.6	0.4	-1.8	-0.4	1.7
Triglycerides	0.5	0.8	2.7	0.9	0.8	0.7	0.6	1.0	0.9	0.9	0.3	0.6	1.2	0.9	1.4	0.4	0.6	1.5	-0.0	-0.3	0.4	1.6
Height	0.5	10.1	28.8	-5.4	-3.9	-3.3	-4.6	-4.0	-2.2	-2.5	-3.6	-2.1	-2.8	-4.5	-3.5	-1.8	-2.9	-1.0	-1.7	-0.6	-2.6	-3.0
Lung FEV1/FVC ratio	0.5	2.5	8.3	-1.0	-2.3	-1.3	-1.1	-1.9	-2.9	-1.5	-1.3	-1.5	-2.5	-1.3	-2.0	-1.5	-1.2	-1.1	-0.6	0.2	-1.3	-0.6
Relative age of first facial hair	0.5	1.1	3.5	0.5	0.3	0.3	1.0	0.7	1.4	0.7	1.0	1.0	1.7	0.7	1.9	1.2	1.1	1.1	1.0	-1.2	0.5	1.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.3	-0.5	-0.6	-0.6	-0.0	-0.8	-1.5	-0.7	0.7	0.7	-1.1	-0.6	-1.1	0.4	-0.6	0.1	1.5	-0.4	-0.7	0.2
Angina	0.5	0.6	3.7	1.7	0.4	1.0	0.2	0.9	-0.6	0.5	0.5	-0.2	-0.3	0.6	-0.9	0.1	0.3	1.9	0.0	-0.0	0.7	0.5
Medication: Metformin	0.5	0.7	4.9	-0.2	0.3	1.1	0.0	0.0	0.6	0.6	0.4	-0.7	0.1	1.2	1.1	1.2	0.4	2.2	-0.5	0.3	1.2	-0.7
Pack years adult smoking proportion	0.5	0.8	2.2	-0.2	-0.9	0.0	-0.0	0.3	0.2	0.4	-1.1	-1.3	1.0	0.0	0.9	1.5	1.3	0.5	-1.1	1.0	0.5	1.3
Impedance of leg (right)	0.5	2.5	9.3	3.1	0.9	0.6	2.2	2.4	0.3	0.8	1.8	1.9	0.5	0.5	1.1	-0.1	0.4	1.5	2.7	-2.4	-0.8	1.1
Maternal smoking around birth	0.5	0.7	2.6	-0.4	-1.0	0.6	-0.6	-0.5	0.6	0.3	-1.1	-1.2	0.7	0.3	-1.0	-0.1	0.1	0.3	-1.6	1.6	0.8	-0.8
Serious illness, injury or assault to yourself	0.5	0.6	2.9	0.8	-0.0	0.7	1.1	0.2	-0.1	0.9	1.4	1.1	-0.5	0.3	-0.0	0.1	-0.2	0.6	1.7	-0.6	-0.2	0.9
Waist circumference	0.5	1.9	8.0	0.1	-0.7	-0.5	-1.0	-1.6	-2.6	-1.5	0.8	-1.1	-2.1	0.1	-1.3	-2.8	-2.2	-0.8	0.1	-0.9	-1.0	-0.3
Had other major operations	0.5	0.6	2.8	-1.0	-0.3	0.1	-0.3	-0.4	-0.2	-0.3	-0.6	-0.6	-1.0	0.2	-0.5	-0.0	-0.7	-1.3	-1.0	1.7	0.6	-1.1
Forced vital capacity (FVC)	0.5	2.1	10.7	-1.9	-1.6	-1.4	-2.1	-1.0	-0.7	-0.9	-2.1	-0.9	-0.9	-1.9	-1.3	-0.1	-0.2	-0.7	-1.5	0.4	-0.6	-3.3
Qualifications: None of the above	0.5	1.1	5.6	0.3	-1.7	-1.2	-0.8	-0.1	-2.4	-1.1	-0.1	-0.8	-1.1	-1.1	-1.2	-0.5	-0.5	-0.7	0.0	-1.2	-1.4	0.7
Medication: Ramipril	0.5	0.7	2.9	1.1	0.4	-0.5	0.0	-0.3	-1.1	-1.1	1.0	0.3	-1.7	-0.3	-0.7	-1.1	-0.9	-0.6	0.7	-0.7	-0.9	-0.1
Impedance of arm (right)	0.5	2.4	7.8	2.6	1.2	0.5	2.1	2.1	0.9	1.0	2.1	1.9	0.7	0.4	1.2	0.0	-0.3	0.2	2.8	-2.0	-0.4	1.9
Father’s age at death	0.5	0.7	2.2	0.0	0.5	0.3	0.9	0.2	1.1	0.6	0.9	0.9	1.5	0.6	1.0	0.7	0.8	0.7	0.9	-0.7	0.3	1.4
Medication: Cholesterol lowering	0.5	0.8	3.5	0.1	-0.5	-0.1	-0.4	-0.1	-1.5	-0.5	1.4	0.2	-1.9	-0.4	-1.4	-0.2	-1.5	0.2	1.0	0.5	-0.6	0.5
Impedance of arm (left)	0.5	2.3	7.4	2.2	1.0	0.1	2.0	1.9	0.7	0.6	1.9	1.7	0.8	0.2	1.4	-0.1	-0.2	0.4	2.7	-2.4	-0.8	2.4
Wheeze or whistling in the chest in last year	0.5	0.8	3.8	0.6	1.3	1.3	0.5	0.4	0.7	0.6	0.5	0.3	0.3	1.1	-0.8	-2.0	-1.5	-0.6	0.7	0.9	0.4	0.3
Pulse wave peak to peak time	0.5	0.6	3.7	0.4	1.0	0.7	0.6	0.4	1.1	0.8	0.2	0.6	0.2	0.5	1.0	0.6	0.6	1.0	0.6	-0.3	0.7	1.9
Qualifications: College or University degree	0.5	1.6	5.8	0.1	1.8	1.2	1.3	1.6	2.4	1.7	0.0	1.1	1.6	1.1	1.4	1.3	0.6	0.5	0.1	0.9	1.4	-1.2
Medication: Blood pressure	0.5	0.9	2.5	-1.0	-0.6	-0.8	-1.1	-0.6	-1.3	-1.3	-0.1	-1.1	-1.4	-0.7	-0.9	-0.6	-0.1	-1.6	-0.9	1.0	-0.4	-1.0
Heart disease (mother)	0.5	0.6	2.4	-0.7	-0.6	-0.6	-0.5	-1.0	-0.6	-0.6	-0.1	0.5	-1.4	-0.6	-1.5	-0.8	-0.6	-0.7	0.6	-0.9	-0.8	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.8	0.2	1.1	1.1	1.0	0.3	1.3	1.1	-0.4	0.6	0.4	0.6	0.7	-0.2	0.1	0.9	0.6	-0.1	0.6	0.9
Mood swings	0.5	1.0	2.5	0.5	0.9	1.0	1.1	0.8	-0.1	0.9	1.4	0.8	1.1	0.8	1.1	1.6	1.0	0.6	1.1	0.7	1.0	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.4	0.2	0.2	-0.0	1.0	-0.1	-1.1	-0.1	1.4	1.1	-0.3	0.1	-0.2	-1.0	-0.8	-1.0	1.5	0.1	-0.4	0.6
Breast cancer (self-reported)	0.5	0.6	1.7	-0.9	-0.1	-0.7	0.1	-0.9	-0.4	-1.0	0.1	0.4	-0.5	-0.5	-0.7	-1.2	-1.0	-1.1	0.6	-1.3	-0.9	-0.8
Medication: Gliclazide	0.5	0.6	2.2	-1.2	-0.7	-0.6	-1.2	-0.7	0.2	-0.5	-0.1	-1.0	-0.7	-0.4	0.2	0.9	-0.2	0.9	-0.9	-0.2	0.0	-1.5
Arm fat mass (left)	0.5	2.2	10.6	0.1	-0.0	-0.5	-0.5	-1.5	-2.2	-1.4	1.8	-0.1	-1.8	0.1	-1.4	-3.2	-2.5	-1.0	1.0	-1.7	-1.3	0.2
Medication: Atorvastatin	0.5	0.7	1.6	0.9	0.4	0.8	0.9	0.5	0.5	0.5	-0.5	0.2	0.4	1.0	1.2	0.6	1.3	0.8	-0.2	1.2	0.8	-1.2
Supplements: Calcium	0.5	0.6	2.7	-1.3	-0.3	-0.7	-0.8	-1.3	0.5	-0.7	-1.6	-1.0	-0.0	-0.5	0.3	0.6	-0.2	-0.1	-0.9	0.4	-0.1	-0.2
Leg fat mass (left)	0.5	2.1	9.2	0.5	-0.0	-0.4	-0.5	-1.2	-2.2	-1.2	2.0	0.0	-1.9	0.2	-1.3	-3.0	-2.4	-0.9	1.2	-1.9	-1.3	0.1
Depressed Affect (Nagel 2018)	0.4	0.9	2.6	0.9	0.9	1.0	1.6	0.5	0.4	0.6	1.0	0.8	1.2	1.2	1.6	1.1	0.6	0.2	1.4	-0.1	0.5	0.9
Intelligence (Savage-Jansen 2018)	0.4	1.1	4.1	-2.0	-0.6	-1.0	-1.1	-0.9	0.8	-0.6	-1.4	-1.3	-1.3	-1.0	-0.0	-0.1	-1.1	-0.6	-1.3	0.8	-0.6	-1.3
Crohns Disease (2017)	0.4	1.0	4.1	-0.7	-1.0	-0.8	-1.0	-1.1	-0.7	-0.7	-1.4	-1.6	-0.0	-0.7	-0.1	-0.5	0.0	-1.1	-1.2	2.0	-0.9	-0.6
Major Depression (MDD)	0.4	0.4	3.1	0.4	0.7	0.4	0.7	0.1	1.1	0.4	0.3	0.6	0.2	0.5	-0.1	-0.0	-0.7	0.6	0.9	-1.8	-0.1	0.1
Schizophrenia (2014)	0.4	1.0	4.0	0.5	0.8	0.1	-0.1	0.3	-0.5	-0.1	0.3	-0.8	1.6	0.2	1.0	1.8	2.0	-0.5	-0.5	1.3	0.9	-1.5
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.9	-1.0	-0.4	-0.3	-0.6	-0.2	0.2	-0.6	-0.6	-1.4	1.0	-0.3	-0.5	1.0	0.7	0.1	-1.2	0.5	0.4	0.3
Cardiovascular Disease	0.4	1.3	3.6	-0.2	-0.4	-1.1	-0.4	-0.1	-1.9	-1.1	0.9	0.1	-1.9	-1.1	-1.6	-1.3	-1.4	-1.8	0.6	-0.0	-1.8	-0.4
Respiratory disease	0.4	0.8	4.2	0.5	-0.3	0.2	0.4	-0.2	-0.7	-0.5	1.0	0.2	-0.7	0.5	-1.5	-2.1	-2.0	-0.4	1.1	-0.4	-0.7	0.6
Chronotype (morning person)	0.4	0.9	4.5	-0.4	-0.1	0.1	-0.4	-0.1	0.1	-0.1	-2.1	-0.9	-1.1	-0.4	0.4	0.4	1.0	-0.8	-1.1	1.9	0.7	-1.5
Average weekly spirits intake	0.4	0.5	1.9	-0.5	-1.1	-0.3	-0.3	0.0	0.7	0.1	-1.2	-1.4	-0.0	-0.6	-0.5	1.3	-0.6	0.7	-1.2	-0.1	0.0	0.4
Fed-up feelings	0.4	0.8	4.6	0.7	0.2	0.5	1.3	0.4	0.7	0.7	0.5	0.6	1.0	0.7	2.1	0.6	0.7	0.8	0.6	-0.5	0.1	1.5
Medication: Levothyroxine sodium	0.4	0.6	3.3	-0.4	-1.0	-0.9	-0.5	-1.4	-0.5	-1.1	-0.4	-0.1	-0.4	-0.8	-0.6	-0.3	-0.6	-0.0	0.2	-1.8	-0.9	-0.1
Impedance of leg (left)	0.4	1.8	6.3	2.5	0.7	0.4	1.8	2.0	0.4	0.5	1.4	1.6	0.4	0.4	0.9	0.2	0.2	1.4	2.3	-2.3	-0.7	0.8
Past tobacco smoking	0.4	0.7	2.8	-1.7	-0.9	-0.6	-1.2	-0.9	0.5	-0.5	-1.1	-0.4	-0.6	-0.4	-0.1	0.3	0.8	-0.2	-1.4	1.4	0.2	-0.7
Alcohol usually taken with meals	0.4	0.7	2.3	0.2	0.9	0.8	0.9	0.4	1.0	0.6	1.5	0.7	1.5	1.0	0.7	-0.0	0.3	0.1	1.0	-0.3	0.7	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.7	-1.3	-0.7	-0.3	-1.0	-0.7	-0.4	-0.3	-1.2	-1.2	-0.3	-0.7	-1.1	0.5	-0.4	0.2	-1.0	1.2	-0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.7	-0.5	1.3	0.9	0.6	0.4	0.6	0.6	1.1	0.4	0.5	1.2	-0.0	-0.4	-0.7	0.1	0.4	-0.1	0.6	0.7
Diabetes (self-reported)	0.4	0.6	2.3	-1.1	-1.3	-0.1	-1.1	-0.9	-0.5	-0.2	0.2	-1.1	-1.1	-0.1	-0.0	0.4	-0.7	1.5	-0.8	0.9	-0.1	-0.6
Alcohol intake versus 10 years previously	0.4	0.6	1.8	-0.6	-1.2	-0.8	-0.3	-0.6	-0.0	-0.6	-1.2	-1.4	0.7	-0.8	0.6	0.9	0.6	0.1	-0.5	-0.2	-0.5	1.0
Falls in the last year	0.4	0.6	1.9	-0.5	-0.6	-0.4	-0.7	-1.0	-0.8	-0.2	-0.5	-0.8	-0.9	-0.6	-0.8	-0.6	-1.4	-0.8	-0.4	1.2	-0.5	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	1.0	6.5	-1.4	-0.1	-1.1	-1.2	0.3	-0.1	-0.9	-0.7	-0.5	-0.6	-1.2	-0.1	0.6	0.5	-0.9	-1.4	0.9	0.1	-2.5
Asthma	0.4	0.7	2.1	-0.5	-0.7	-0.0	-0.4	-0.5	-0.7	-0.5	-0.9	-1.3	-0.8	-0.2	-0.9	-1.4	-1.4	-0.9	-0.6	1.4	-0.4	0.6
Length of working week for main job	0.4	0.5	1.3	1.0	-0.8	-0.3	-0.3	0.6	0.5	-0.1	-0.7	-1.1	-0.4	-0.8	-0.4	-1.1	-0.6	0.1	-1.1	-0.3	-0.8	0.0
Hair/balding pattern: Pattern 4	0.4	1.0	4.7	0.4	-0.1	-0.3	1.0	-0.1	-0.8	-0.7	1.8	1.6	-0.5	0.7	-0.8	-0.9	-0.4	-1.1	2.2	-1.5	-1.0	0.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	3.5	0.1	0.3	-0.7	0.5	0.0	0.6	-0.5	0.4	0.5	1.1	-0.1	0.6	-0.7	0.4	-1.1	0.8	-1.9	-0.8	-0.2
Medication: Paracetamol	0.4	0.7	2.9	0.5	-0.1	0.8	-0.1	0.1	0.0	0.5	-1.2	-1.0	-0.0	0.7	-0.1	0.5	1.2	-0.4	-1.4	0.9	1.1	-1.7
Headache pain in last month	0.4	0.7	3.0	-1.0	0.1	0.6	-0.6	-1.2	-0.8	0.3	-1.3	-0.4	0.4	0.6	-1.1	-1.4	-0.4	-0.5	-0.3	1.7	0.3	-1.0
Comparative body size at age 10	0.4	1.2	4.6	2.1	1.1	0.9	1.8	1.2	0.2	0.5	1.7	1.0	0.5	1.8	0.6	-0.1	0.0	0.4	0.9	0.2	0.3	1.7
Health satisfaction	0.4	0.5	2.7	0.8	0.7	1.0	0.8	-0.6	0.2	-0.1	1.1	0.0	0.7	1.7	-0.3	-0.5	-0.5	0.0	0.9	-0.2	0.7	0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.4	3.6	-0.1	-0.9	-0.3	-0.0	-1.0	-0.2	-0.4	0.2	-0.4	-0.2	-0.1	0.5	-0.3	-0.6	0.3	0.7	-0.8	-0.6	1.9
Emphysema/chronic bronchitis	0.4	0.4	1.6	0.6	0.0	1.0	0.1	1.3	1.0	0.8	0.1	-0.2	-0.0	0.8	-0.6	-0.9	-1.1	0.5	-0.1	-0.2	0.6	-0.3
Angina (self-reported)	0.4	0.5	3.2	1.5	0.3	1.0	0.1	0.6	-0.7	0.4	0.4	-0.3	-0.2	0.5	-0.8	0.0	0.3	1.8	-0.0	0.1	0.7	0.5
Medication: Seretide 50 evohaler	0.4	0.5	1.7	0.4	0.7	1.0	1.2	0.4	-0.2	0.6	0.4	-0.2	1.3	1.0	0.0	0.2	0.7	0.2	0.7	1.0	0.4	1.0
Pulse rate, automated reading	0.4	1.2	9.4	-0.6	-0.5	-0.4	-1.1	-0.8	-1.2	-0.8	-0.6	-0.9	-1.6	-0.4	-0.3	-0.1	-0.2	-0.6	-1.4	1.6	-0.2	-3.1
Smoking status: Previous	0.4	0.6	3.6	1.1	0.6	0.2	0.7	0.3	-0.7	0.1	1.0	0.2	-0.1	-0.1	-0.3	-0.7	-1.0	0.2	1.3	-1.9	-0.5	0.9
Average weekly red wine intake	0.4	0.5	1.7	0.5	0.7	0.6	0.4	1.1	1.3	0.9	-0.1	0.5	0.5	0.4	0.5	1.0	0.8	0.3	-0.6	0.3	0.9	-1.0
Miserableness	0.4	0.8	2.6	0.6	1.0	0.7	1.3	0.6	0.8	0.5	0.5	0.7	1.5	1.0	1.6	0.7	0.7	0.2	0.9	-0.2	0.8	1.0
High cholesterol (Self-reported)	0.4	0.7	2.8	0.1	0.3	0.6	0.7	1.1	0.0	0.5	1.7	1.5	-0.9	0.4	-0.7	-0.2	-0.8	-0.5	1.6	0.3	-0.2	0.3
Medication: Lisinopril	0.4	0.5	1.5	-0.0	1.0	0.6	0.4	0.2	1.2	0.5	-0.7	-0.7	0.4	0.5	0.8	0.9	0.9	-0.2	-1.0	0.9	0.9	-0.6
Illnesses of father: High blood pressure	0.4	0.5	2.0	-1.1	-0.8	-0.4	-1.0	-1.2	-0.7	-0.3	-0.4	-0.1	-0.8	-0.9	-1.4	-0.4	-0.6	-0.0	-0.2	0.5	-0.5	0.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	2.0	-0.3	0.2	0.1	-0.1	-0.7	-0.4	-0.3	-0.5	-0.1	-1.4	-0.1	0.1	-0.9	-1.0	-0.9	-0.2	0.9	0.2	-1.3
Basal cell carcinoma (self-reported)	0.4	0.5	1.5	1.2	0.5	0.7	1.0	-0.2	0.4	0.3	0.9	0.4	0.6	1.2	-0.1	-0.3	0.2	-0.2	0.9	-0.5	0.4	1.0
Heart disease (siblings)	0.4	0.5	2.3	1.0	-0.5	0.1	-0.2	0.3	-1.5	-0.2	0.7	0.5	-1.5	-0.2	-1.1	-0.2	-1.1	0.3	0.5	0.2	-0.3	-0.4
Pack years of smoking	0.4	0.6	2.6	0.1	-0.9	0.1	0.1	0.3	0.1	0.4	-0.8	-1.2	0.8	0.2	0.7	1.3	1.0	0.7	-0.7	0.7	0.3	1.6
Impedance of whole body	0.4	1.9	5.5	2.3	0.7	0.1	1.8	2.1	0.7	0.5	1.5	1.5	0.7	0.0	1.3	0.2	0.3	0.8	2.3	-2.4	-0.8	1.5
Bipolar Disorder or Schizophrenia	0.3	0.7	3.3	-0.1	0.5	0.2	-0.3	-0.2	-0.9	-0.3	0.8	-0.6	0.4	0.5	0.6	1.2	1.2	-0.8	-0.4	1.6	0.9	-1.8
Alzheimer’s Disease (in mother)	0.3	0.3	2.5	0.3	0.6	0.7	0.3	-0.3	0.6	0.2	0.1	0.6	-0.1	0.8	0.2	-1.0	-0.1	0.4	-0.0	0.1	0.4	1.6
Irritable Bowel Disease (IBD)	0.3	0.8	4.1	-0.7	-0.4	-0.5	-0.6	-1.2	-0.0	-0.3	-1.0	-1.1	0.8	-0.2	0.7	0.5	1.1	-1.3	-0.6	2.0	-0.1	-0.9
Ulcerative Colitis (UC)	0.3	0.6	2.4	-0.7	0.3	-0.1	0.1	-1.0	0.2	0.1	0.1	0.3	1.1	0.4	0.7	0.9	1.3	-1.5	0.6	1.5	0.4	-0.8
Breast Cancer	0.3	0.8	2.2	0.4	0.8	1.4	0.6	0.9	1.2	1.5	0.0	0.1	0.5	0.8	0.8	0.6	0.1	1.0	-0.2	1.3	0.9	1.4
Ovarian Cancer	0.3	0.4	1.9	0.5	-0.2	0.1	0.1	0.5	-0.4	-0.0	0.6	-0.3	0.4	0.2	1.0	1.4	0.7	1.0	0.0	-0.8	0.8	-0.3
Blood Platelet Count	0.3	3.1	18.5	2.0	0.9	1.8	1.8	2.7	0.8	1.6	2.4	0.9	1.8	1.9	0.8	0.5	1.4	-0.2	0.4	0.5	1.4	4.3
Hypothyroidism (self reported)	0.3	0.8	3.3	0.2	-1.1	-0.7	-0.7	-0.6	-0.6	-0.6	-0.7	0.2	-1.5	-0.7	-1.8	0.1	-0.5	0.6	-0.1	-1.6	-0.7	-1.1
Number of treatments/medications taken	0.3	0.6	2.1	0.1	0.9	1.0	0.4	-0.4	0.2	0.4	1.5	1.0	-0.4	0.9	-0.8	-0.3	-0.8	-0.5	1.3	1.0	0.6	-0.7
Sensitivity / hurt feelings	0.3	0.5	1.6	0.8	0.7	1.3	1.1	0.7	0.2	1.0	0.2	0.2	0.8	1.0	0.6	0.4	0.4	0.5	0.3	1.2	0.8	0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.6	-0.5	-0.2	0.0	-0.3	0.5	-0.6	0.2	0.3	-0.5	-0.5	0.4	0.1	1.0	0.1	0.5	-0.4	1.1	0.5	-1.3
Medication for hormone replacement therapy	0.3	0.3	2.0	-0.5	-0.3	0.3	0.2	0.0	-0.1	0.2	1.1	0.3	0.2	0.1	-0.3	0.5	-0.3	0.8	1.1	-0.2	0.1	1.4
Vitamin and mineral supplements	0.3	0.5	1.3	1.1	-0.8	0.2	-0.5	0.3	-1.0	-0.2	-0.9	-1.1	-0.4	0.2	0.1	-0.7	0.5	-0.2	-1.1	0.8	-0.0	-0.7
Diabetes (father)	0.3	0.4	1.6	-1.1	-0.5	-0.3	-0.3	0.4	-0.5	-0.4	1.1	0.2	-1.1	-0.4	-0.2	-0.8	-0.6	-0.1	0.2	-0.7	-0.6	1.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	0.5	-0.1	-0.3	-0.0	-0.9	-0.5	-0.9	0.2	-0.0	0.3	0.1	-0.0	-0.7	-0.0	0.4	0.5	-0.7	-0.6	1.0
Supplements: Glucosamine	0.3	0.4	2.2	-1.4	0.9	0.1	-0.4	-0.1	1.5	0.8	0.0	-0.4	0.9	-0.1	-0.3	-0.1	-0.6	-0.2	-0.8	0.5	0.3	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.3	0.6	0.5	0.5	-0.3	-0.2	0.7	0.5	-0.6	-0.1	0.6	0.5	0.4	-0.2	0.2	1.1	-1.1	-0.2	1.1	-0.9
Body mass index (BMI)	0.3	1.3	6.9	0.7	0.4	0.1	-0.0	-0.9	-1.7	-0.8	1.9	0.1	-1.1	0.8	-0.8	-2.6	-1.7	-0.6	0.8	-1.2	-0.7	0.7
Number of incorrect matches in round	0.3	0.6	1.8	0.8	-0.3	0.7	0.5	0.2	1.2	0.6	0.5	-1.3	1.3	1.1	1.1	0.4	0.3	0.4	-0.7	0.1	0.7	0.5
Hearing difficulty/problems with background noise	0.3	0.5	3.7	-0.4	-0.5	0.1	-0.7	-0.8	0.4	-0.2	-1.9	-1.0	-0.3	-0.4	0.1	-0.4	-0.6	-0.2	-1.0	1.3	0.4	-0.5
Allergy	0.3	0.6	3.8	-0.0	0.0	-0.8	0.2	-0.9	0.2	-0.7	-0.3	0.7	0.2	-0.6	1.2	1.9	1.5	0.8	-0.1	-0.2	-0.2	-0.9
Hip circumference	0.3	1.3	4.6	-0.3	-0.5	-0.5	-0.9	-1.5	-2.1	-1.3	0.7	-0.5	-1.6	-0.2	-1.2	-2.1	-1.8	-0.4	0.3	-0.9	-0.9	-0.3
Pulse wave reflection index	0.3	0.4	1.9	0.1	-0.3	-0.5	0.6	1.2	-0.3	0.1	0.4	0.5	1.4	-0.3	1.0	0.7	0.7	0.3	-0.1	-0.7	-0.2	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.2	0.8	0.3	0.0	0.7	0.3	1.3	0.6	-0.5	0.2	1.5	0.3	1.1	-0.1	-0.0	1.0	0.1	-1.2	-0.1	0.5
Glaucoma (self-reported)	0.3	0.4	1.8	-0.1	-1.4	-0.4	-0.5	-0.2	-0.5	-0.3	-0.9	-0.6	-0.8	-0.3	-0.2	0.2	-0.3	0.6	-1.0	0.3	0.1	-1.1
Gout (self-reported)	0.3	0.4	2.7	0.1	-0.3	-0.5	-0.4	0.5	-1.1	-0.7	-0.1	-1.6	0.1	-0.3	-0.3	-0.0	0.1	0.1	-0.9	0.2	-0.2	-0.6
Worry too long after embarrassment	0.3	0.6	1.7	1.0	0.7	0.7	0.9	1.3	0.4	0.7	0.7	0.8	0.5	0.6	0.5	1.0	0.5	0.8	0.9	-0.3	0.4	0.9
Shortness of breath walking on level ground	0.3	0.3	2.1	0.3	0.4	0.8	-0.0	0.0	-0.1	0.7	0.9	0.2	0.3	0.6	-0.8	-0.0	-0.3	-0.2	0.2	1.4	0.6	-0.1
Medication: Ibuprofen	0.3	0.4	1.9	0.3	1.4	0.5	0.4	0.4	1.4	0.4	0.1	0.1	0.8	0.8	0.7	-0.6	-0.2	-0.2	-0.6	-0.4	0.4	-0.2
Alcohol intake frequency.	0.3	0.6	3.0	-0.6	-0.7	-0.7	-0.3	-1.6	-1.7	-1.3	0.6	-0.6	-0.4	-0.4	-0.6	-0.2	-0.3	-0.3	0.6	0.5	-0.7	0.2
Overall health rating	0.3	0.6	2.7	0.2	-0.7	0.3	0.0	-1.2	-1.6	-0.7	0.7	-0.9	-0.3	0.5	-0.8	-0.9	-1.3	-0.2	0.7	0.3	-0.3	0.9
Ever had bowel cancer screening	0.3	0.4	1.9	0.5	-0.3	0.5	0.7	0.1	0.1	0.2	1.4	1.1	-0.3	0.3	-0.6	0.0	-0.1	0.1	1.3	-0.8	-0.1	0.1
Medication for cholesterol	0.3	0.5	1.4	0.4	0.9	0.6	0.4	0.9	0.2	0.9	-0.3	0.1	1.2	0.6	1.2	0.6	1.0	0.8	-0.4	0.2	1.0	0.0
Smoking status: Current	0.3	0.5	1.3	-0.6	-1.2	-1.2	-0.4	-0.1	-0.8	-1.1	-0.4	-0.5	0.1	-1.0	-0.6	0.5	-0.4	-0.7	-0.2	0.3	-1.1	0.6
Average weekly champagne plus white wine intake	0.3	0.4	0.9	0.2	0.5	0.5	0.8	-0.0	0.9	0.6	0.8	0.5	0.9	0.6	0.7	0.1	0.4	-0.6	0.2	0.6	0.4	0.8
Hearing aid user	0.3	0.3	1.0	0.4	1.0	0.6	0.6	1.0	0.9	0.7	0.2	-0.1	-0.3	0.5	0.2	0.1	-0.2	-0.1	-0.2	0.5	0.3	-1.0
Financial situation satisfaction	0.3	0.4	2.0	-0.4	-0.4	-0.1	-0.5	-1.4	0.3	-0.6	0.2	-0.5	0.6	0.1	-0.4	-1.0	-0.3	-0.7	-0.0	-0.8	-0.0	1.2
Alcohol drinker status: Never	0.3	0.3	1.5	0.3	-0.5	-0.1	0.2	-0.4	-0.8	-0.5	0.5	0.2	-0.7	-0.0	-1.2	-0.1	-0.2	-0.4	1.0	-0.5	-0.4	0.8
Ever smoked	0.3	0.5	1.5	1.0	0.4	0.2	0.9	0.9	-0.7	0.2	0.9	0.2	0.3	0.1	-0.0	-0.2	-1.2	0.1	1.1	-1.0	-0.4	0.8
Average weekly beer plus cider intake	0.3	0.5	1.2	-0.6	0.2	0.9	-0.5	-0.5	0.7	0.7	-0.9	-0.7	0.8	0.3	-0.0	1.1	0.5	0.9	-0.9	0.6	1.1	0.6
Pain experienced in last month	0.3	0.5	3.8	-0.1	-0.4	-0.4	0.0	0.6	0.6	0.2	-0.6	0.8	0.4	-0.5	0.0	1.7	2.0	0.1	-0.6	-0.2	0.4	-0.3
Bipolar Disorder (2018)	0.2	0.2	1.6	-0.0	-0.1	0.1	0.1	-0.7	-0.3	-0.4	1.3	-0.1	-0.1	0.7	-0.1	-0.2	-1.0	-0.2	0.5	0.4	-0.2	0.2
Fasting Glucose	0.2	0.3	1.3	0.5	0.4	0.7	0.3	0.1	0.8	0.7	0.3	-0.0	0.1	0.7	0.5	-0.1	0.4	0.3	0.5	-1.2	0.7	-0.0
Ulcerative Colitis	0.2	0.3	1.2	-0.7	0.1	-0.2	-0.1	-1.1	-0.2	-0.4	-0.2	-0.4	0.7	0.4	0.4	0.2	0.7	-0.9	0.2	0.7	-0.0	-0.3
BMI	0.2	1.4	5.4	1.3	0.4	0.2	0.1	-0.3	-2.0	-0.8	2.3	-0.5	-1.4	0.8	-1.1	-2.3	-1.5	-0.0	0.6	-1.1	-0.7	0.2
Allergy or Eczema	0.2	0.5	2.3	-0.0	-0.2	0.6	-0.5	0.9	-0.1	0.5	-0.3	-1.5	-0.6	0.5	-0.8	-0.1	-0.4	-0.2	-1.3	1.5	0.7	0.1
Lung FVC	0.2	0.8	3.7	0.2	-0.6	0.0	-0.3	0.5	0.5	0.5	-1.9	-0.3	0.2	-0.3	0.8	1.5	1.2	0.2	-1.1	1.4	0.8	-1.3
Tanning	0.2	1.9	5.8	1.8	1.3	1.2	1.8	1.4	0.7	1.1	2.4	1.4	0.8	1.2	1.2	-0.0	-0.2	1.3	1.7	-1.7	0.1	2.0
Hand grip strength (left)	0.2	0.5	1.5	-0.8	-0.0	-0.2	-1.2	-0.7	0.3	0.0	-0.5	-0.7	-0.1	-0.1	-0.4	-1.2	-1.2	0.7	-0.6	-0.8	-0.6	-0.7
Supplements: Zinc	0.2	0.3	1.6	-0.3	-0.4	-0.5	-0.5	-0.3	0.8	-0.3	-0.4	-1.0	-0.4	-0.4	-0.3	0.3	-0.1	0.1	-1.2	-0.1	0.3	0.0
Diabetes (mother)	0.2	0.3	0.9	0.9	-0.8	0.2	0.2	0.5	-0.9	0.1	-0.3	0.1	-0.6	0.3	-0.3	0.9	0.5	0.3	0.5	0.7	0.3	0.1
Average weekly fortified wine intake	0.2	0.2	0.9	0.1	0.0	-0.0	0.2	-0.9	0.5	-0.8	-0.9	-0.4	-0.4	0.4	-0.1	-0.1	-0.2	-0.7	-0.4	0.3	0.1	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.1	-0.3	0.3	0.6	0.1	-0.5	-0.0	0.4	0.4	-0.1	0.7	0.8	0.3	-0.2	-0.5	1.0	0.4	-0.8	0.4	0.2
Relative age voice broke	0.2	0.3	1.5	-0.8	-0.0	0.1	-0.2	0.3	1.2	0.4	-0.2	-0.2	0.6	0.0	0.2	1.1	0.8	0.5	-0.5	0.4	0.6	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.2	-0.2	-0.2	0.6	-0.5	0.9	0.3	0.9	-0.4	-1.1	0.1	0.4	-1.0	-0.5	-0.3	-0.4	-1.0	0.7	0.5	0.2
Multivitamins +/- minerals	0.2	0.3	2.2	-1.5	0.2	-0.6	-0.2	-0.6	0.6	-0.2	0.1	-0.3	0.4	-0.8	-0.1	0.3	-0.5	-0.5	-0.0	-0.5	-0.2	0.9
Medication: Atenolol	0.2	0.3	0.9	0.6	0.5	0.7	0.0	0.6	0.1	0.6	0.6	0.6	0.1	0.2	-0.4	0.9	0.4	-0.0	0.2	0.8	1.0	-0.5
High blood pressure (mother)	0.2	0.2	0.6	0.4	0.3	0.8	0.2	-0.5	-0.3	0.6	0.5	0.3	-0.7	0.2	-0.5	-0.6	-0.4	0.5	0.7	0.4	0.5	-0.4
Had menopause	0.2	0.2	0.7	-0.7	-0.5	0.1	-0.3	-0.1	0.3	0.4	0.5	0.2	0.7	-0.1	-0.1	0.2	-0.8	0.5	0.8	-0.6	-0.0	0.4
Financial difficulties in last 2 years	0.2	0.3	1.0	0.4	0.4	0.1	0.4	-0.3	0.4	-0.3	0.2	0.2	0.3	0.5	0.6	-0.9	-0.5	-1.0	0.8	-0.2	-0.2	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.2	0.1	1.1	0.3	0.5	-0.0	1.1	0.1	0.1	0.3	0.6	0.8	0.6	-0.8	-0.6	-0.3	-0.1	-0.4	0.2	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	2.2	-0.8	0.2	0.3	0.1	-0.0	0.1	0.2	-0.5	-0.0	0.3	0.1	-0.1	1.0	0.2	0.3	-0.5	1.5	0.7	0.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	2.2	-0.0	-0.8	-0.7	-0.7	-1.0	-0.9	-0.8	0.1	-0.1	-0.7	-0.7	-0.8	0.1	-0.3	0.2	0.2	-1.5	-0.6	-0.5
Birth weight	0.2	0.4	2.0	-1.0	-0.4	-0.4	-1.0	-0.3	-0.3	0.1	-0.8	-0.8	0.0	-0.6	0.0	0.5	-0.1	-0.2	-0.8	1.4	0.3	0.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.3	-0.2	0.3	0.3	0.1	1.1	0.3	0.8	0.7	0.3	0.5	0.1	-0.5	-0.1	0.4	-0.6	-0.1	-0.1	0.2	0.9
Medication: Allopurinol	0.2	0.3	1.6	0.6	-0.1	0.4	0.4	1.0	-0.5	0.2	-0.1	-1.2	0.4	0.5	0.1	0.0	0.6	0.2	-0.6	0.4	0.3	-0.5
Medication: Omeprazole	0.2	0.2	0.9	-0.3	0.2	0.1	0.4	-0.2	-0.3	-0.1	0.3	0.6	-0.7	-0.0	0.2	-0.6	-1.0	-0.6	0.6	0.4	0.0	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.4	-0.7	-1.2	-0.2	-0.4	-0.6	0.6	-0.0	-0.3	0.1	0.2	-0.2	-0.1	0.7	0.0	0.1	0.2	-0.2	-0.0	1.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.6	0.1	-0.1	-0.4	-0.1	-0.0	-1.0	-0.6	0.7	0.3	-0.3	-0.6	-0.2	-0.3	-0.3	-0.5	0.5	0.1	-0.6	1.3
Supplements: Vitamin C	0.2	0.3	0.9	-0.6	0.7	0.0	0.7	0.3	1.0	0.3	-0.2	0.9	-0.3	-0.1	-0.1	0.6	-0.1	0.6	0.5	-0.1	0.0	-0.8
Qualifications: nursing, teaching	0.2	0.3	1.0	-1.0	0.7	-0.6	-0.1	-0.7	0.7	-0.8	0.4	1.0	-0.2	-0.2	0.4	-0.5	-0.6	-0.9	0.4	-0.2	-0.2	0.0
Osteoporosis (self-reported)	0.2	0.2	1.3	0.4	0.7	0.6	0.1	0.5	1.1	0.8	0.1	-0.3	0.6	0.4	0.3	0.4	0.2	0.4	-0.2	-0.1	0.6	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	3.3	0.2	-0.8	-0.7	-0.5	-0.5	-0.4	-0.6	-0.2	0.3	-1.3	-0.8	-0.4	0.1	0.4	-0.5	-0.1	-0.6	-0.3	-1.8
Ever taken oral contraceptive pill	0.2	0.2	1.1	0.2	0.2	-0.7	-0.2	0.4	-0.1	-0.6	-0.5	-0.2	-0.2	-0.6	0.7	1.1	0.5	-0.5	-0.6	0.2	0.2	-0.6
Commuting to job workplace: Public transport	0.2	0.3	1.3	0.0	0.2	0.6	0.5	0.5	0.8	0.6	-0.2	0.6	0.6	0.6	0.3	0.3	0.5	0.1	0.3	-0.2	0.8	-1.1
Eye problems/disorders: Glaucoma	0.2	0.3	1.5	0.7	-0.5	0.1	0.1	0.6	0.1	0.4	-0.4	0.1	-0.2	-0.0	0.4	0.4	0.1	1.2	-0.4	-1.0	0.3	-0.9
Vascular/heart problems diagnosed by doctor	0.2	0.4	2.8	-0.1	0.6	0.7	0.4	0.4	1.7	0.9	-0.2	0.5	0.8	0.5	0.8	-0.1	-0.6	0.8	-0.0	-0.1	0.6	0.0
Depression (Nagel 2018)	0.1	0.2	1.0	-0.1	0.4	0.3	0.6	0.3	0.4	0.1	0.9	0.8	0.2	0.5	0.2	0.0	-0.3	0.3	1.0	-0.6	-0.0	-0.3
Reaction Time	0.1	0.2	0.8	-0.6	-0.9	-0.7	-0.2	-0.2	-0.5	-0.8	0.0	-0.4	0.4	-0.6	0.2	-0.2	-0.3	-0.0	-0.1	0.1	-0.7	0.7
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.8	-0.3	1.0	-0.0	0.5	0.1	1.4	0.4	-0.1	0.6	0.1	0.2	1.0	0.2	-0.1	-0.1	0.0	0.2	-0.2	-0.6
LDL Cholesterol	0.1	0.2	1.1	-0.2	-0.0	-0.2	-0.9	0.2	-0.1	-0.3	0.5	0.2	0.1	-0.2	-1.0	-0.1	-0.0	0.0	-0.0	-0.9	0.1	-0.6
Blood Eosinophil Count	0.1	0.5	1.6	1.0	0.2	0.3	0.4	0.9	-1.0	-0.1	0.1	-1.0	-1.2	-0.1	-1.1	-0.8	-0.8	-0.5	-0.2	-0.2	-0.4	0.5
Heel T-Score	0.1	1.1	3.3	-1.8	0.1	-1.6	-0.1	-0.6	1.1	-1.4	-1.1	-0.3	-0.2	-1.0	0.7	-1.0	-0.3	-1.8	-0.4	-1.2	-1.2	-0.7
Waist Hip Ratio (WHR)	0.1	0.4	1.5	-0.1	-0.3	-0.2	-0.5	-0.3	-0.8	-0.5	-0.2	-1.2	-1.1	0.2	0.0	-1.0	-0.5	-0.9	-0.9	0.1	-0.0	-0.9
Smoking Status	0.1	0.3	1.4	0.8	0.4	-0.2	0.8	0.9	-0.5	-0.2	0.5	-0.0	0.2	-0.3	0.0	0.5	-0.9	0.2	0.7	-0.6	-0.7	1.2
Hair Pigment	0.1	3.5	12.7	-2.2	-1.9	-2.2	-1.4	-1.4	0.3	-2.1	-3.0	-3.4	1.0	-0.9	0.8	0.3	1.1	-1.8	-3.6	0.3	-0.7	-2.2
Severe depression (siblings)	0.1	0.1	0.5	-0.1	-0.3	-0.2	-0.1	0.6	0.4	0.4	0.1	0.1	0.0	-0.2	-0.4	0.6	-0.3	-0.6	-0.0	0.7	0.4	0.3
High blood pressure	0.1	0.4	1.7	-0.1	-0.4	-0.8	-0.4	-0.6	-1.3	-1.0	0.1	-0.6	-0.5	-0.5	-0.4	-0.2	0.4	-1.2	-0.0	0.1	-0.6	0.3
Hair/balding pattern: Pattern 2	0.1	0.1	0.3	-0.5	0.0	0.0	-0.4	0.0	0.3	0.3	-0.3	0.4	0.5	-0.1	0.0	-0.2	0.5	-0.3	-0.0	-0.1	0.1	0.2
Tense / ‘highly strung’	0.1	0.1	0.6	-0.5	0.0	0.5	-0.4	-0.4	0.8	0.4	-0.3	-0.0	-0.2	-0.1	0.2	0.2	-0.5	-0.2	-0.1	0.6	0.5	-0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.8	-0.4	0.3	0.0	-0.0	-0.0	0.8	0.2	0.9	0.7	0.5	-0.1	-0.0	0.0	0.6	-0.1	0.3	-0.5	0.1	0.1
Number of full brothers	0.1	0.2	0.5	-0.1	-0.6	0.0	-0.6	-0.5	-0.7	-0.1	0.1	-0.4	-0.4	-0.4	-0.4	-0.3	-0.6	0.3	-0.1	-0.5	0.0	-0.4
Medication for pain relief, constipation, heartburn	0.1	0.3	1.5	-0.4	0.2	0.0	0.0	0.3	0.6	0.5	0.5	0.6	0.3	-0.2	0.4	0.6	0.1	1.2	0.5	-0.4	0.1	0.9
Neck or shoulder pain in last month	0.1	0.2	0.8	0.6	-0.0	0.5	-0.1	-0.0	0.5	0.3	-0.7	-0.8	0.3	0.3	0.3	0.1	-0.3	0.1	-0.9	0.3	0.3	-0.3
Mean time to correctly identify matches	0.1	0.3	1.7	0.1	-0.4	0.1	0.5	0.5	0.3	-0.1	0.4	-0.5	1.0	0.1	0.7	0.6	-0.1	0.7	0.1	-0.0	-0.0	1.3
Suffer from ‘nerves’	0.1	0.2	0.9	0.1	0.2	0.0	-0.3	-0.0	-0.7	-0.3	0.5	0.0	0.0	-0.2	0.0	-0.2	-0.9	0.3	0.6	-0.2	-0.6	0.7
Knee pain experienced in last month	0.1	0.2	1.2	-0.1	-0.0	-0.2	-0.2	-0.1	0.4	0.1	-0.1	-0.5	-0.5	-0.5	-0.6	-0.5	-1.1	0.2	0.2	-0.6	-0.8	0.2
Hypertension (Self-reported)	0.1	0.4	1.6	-0.0	-0.5	-0.9	-0.4	-0.5	-1.3	-1.0	-0.0	-0.7	-0.7	-0.6	-0.5	-0.4	0.1	-1.2	-0.1	0.0	-0.8	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	-0.3	-0.0	-0.8	-0.5	-0.3	0.0	-0.3	-0.5	0.2	-0.6	-0.5	-0.1	0.3	-0.7	-0.8	-0.1	-0.6	-0.5	-0.1
Medication: Blood pressure	0.1	0.3	0.7	-0.0	-0.3	-0.6	0.5	-0.6	-0.1	-0.7	0.6	0.3	-0.2	-0.2	-0.5	-0.2	-0.6	-0.7	0.8	-0.5	-0.8	0.5
Ever depressed for a whole week	0.1	0.2	0.9	-0.3	0.2	0.1	-0.1	-0.2	0.1	-0.0	0.1	0.5	-0.4	0.2	-0.4	-0.9	-0.6	-0.4	0.6	-0.5	-0.3	0.3
Myopia	0.1	0.2	0.8	-0.4	0.1	-0.2	-0.4	-0.8	-0.4	-0.6	0.1	0.1	-0.9	-0.2	0.5	-0.3	-0.4	0.7	0.3	-0.6	-0.0	-0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

HDHD3

Models

Trait associations