TWAS hub - ARV1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1990	0.0340	0.0e+00	0.172	0.176	0.224	0.218	0.235	2.0e-20	6.3e-21	7.6e-27	4.7e-26	3.4e-28
2	GTEx	Adipose Subcutaneous	0.1350	0.0420	1.4e-04	0.048	NA	0.038	NA	0.040	7.8e-05	NA	4.3e-04	NA	2.9e-04
3	GTEx	Adipose Visceral Omentum	0.1680	0.0520	3.9e-04	0.061	NA	0.063	NA	0.089	4.5e-04	NA	3.5e-04	NA	2.4e-05
4	GTEx	Artery Aorta	0.2090	0.0660	5.9e-04	0.082	NA	0.034	NA	0.070	2.9e-05	NA	5.8e-03	NA	1.1e-04
5	GTEx	Artery Coronary	0.1870	0.0680	2.7e-03	0.146	NA	0.029	NA	0.075	1.3e-05	NA	3.7e-02	NA	1.7e-03
6	GTEx	Cells EBV-transformed lymphocytes	0.1890	0.0690	3.9e-03	0.093	NA	0.100	NA	0.120	6.0e-04	NA	3.8e-04	NA	1.0e-04
7	GTEx	Cells Transformed fibroblasts	0.1120	0.0420	3.2e-03	0.065	NA	0.057	NA	0.050	1.3e-05	NA	4.4e-05	NA	1.2e-04
8	GTEx	Colon Transverse	0.3380	0.0730	8.5e-08	0.254	NA	0.284	NA	0.284	1.9e-12	NA	6.1e-14	NA	6.6e-14
9	GTEx	Liver	0.2900	0.1050	7.8e-03	-0.006	NA	-0.009	NA	0.003	5.1e-01	NA	6.9e-01	NA	2.7e-01
10	GTEx	Nerve Tibial	0.1003	0.0390	4.1e-03	0.020	NA	0.020	NA	0.002	1.5e-02	NA	1.3e-02	NA	2.1e-01
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1400	0.0530	4.1e-03	-0.005	NA	-0.004	NA	-0.003	8.7e-01	NA	6.8e-01	NA	5.0e-01
12	YFS	Blood	0.0544	0.0125	3.9e-12	0.053	0.041	0.048	0.047	0.050	7.3e-17	2.3e-13	1.9e-15	5.5e-15	4.8e-16
13	TCGA	Bladder Urothelial Carcinoma	0.1110	0.0520	4.5e-03	-0.003	0.003	0.013	NA	-0.003	7.3e-01	1.5e-01	2.7e-02	NA	6.6e-01
14	TCGA	Breast Invasive Carcinoma	0.0254	0.0135	1.7e-03	0.018	0.012	0.014	NA	0.014	9.0e-05	1.1e-03	6.5e-04	NA	5.5e-04
15	TCGA	Cervical Squamous Cell Carcinoma	0.0610	0.0330	4.1e-03	0.036	0.028	0.027	NA	0.040	6.6e-03	1.5e-02	1.7e-02	NA	4.5e-03
16	TCGA	Colon Adenocarcinoma	0.1480	0.0680	5.9e-03	0.004	0.025	0.000	NA	0.004	1.8e-01	1.3e-02	3.0e-01	NA	1.9e-01
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0854	0.0426	7.5e-03	0.014	-0.001	0.017	NA	0.003	8.4e-03	3.9e-01	4.3e-03	NA	1.2e-01
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0459	0.0246	5.5e-04	0.042	0.020	0.027	NA	0.028	1.5e-05	2.0e-03	4.8e-04	NA	3.7e-04
19	TCGA	Brain Lower Grade Glioma	0.0727	0.0299	4.5e-05	0.048	0.043	0.029	NA	0.047	3.3e-06	1.2e-05	2.4e-04	NA	4.1e-06
20	TCGA	Lung Squamous Cell Carcinoma	0.0380	0.0223	4.3e-03	0.030	0.021	0.033	NA	0.031	2.0e-04	1.6e-03	9.8e-05	NA	1.8e-04
21	TCGA	Ovarian Serous Cystadenocarcinoma	0.0690	0.0420	7.4e-03	0.044	0.004	0.011	NA	0.035	5.8e-04	1.5e-01	5.4e-02	NA	2.0e-03
22	TCGA	Prostate Adenocarcinoma	0.0626	0.0334	8.4e-04	0.033	0.043	0.032	NA	0.040	2.0e-04	2.4e-05	2.7e-04	NA	4.3e-05
23	TCGA	Testicular Germ Cell Tumors	0.2130	0.1230	1.1e-03	-0.008	0.055	0.039	NA	0.007	8.8e-01	5.2e-03	1.6e-02	NA	1.8e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Frequency of depressed mood in last 2 weeks	4.0	5.6	10.2	2.4	2.6	1.6	1.8	1.9	2.7	2.5	1.9	3.0	3.2	2.2	2.4	2.6	2.2	1.1	2.5	2.3	2.4	2.3	2.8	2.3	3.2	1.1
Loneliness, isolation	3.9	5.4	9.7	2.7	2.2	2.6	2.5	2.2	2.4	2.2	1.8	1.8	1.7	2.5	2.5	0.3	2.5	2.8	1.3	2.6	2.2	2.3	3.1	1.8	2.6	3.0
Ever had prostate specific antigen (PSA) test	3.5	4.0	9.3	1.9	2.7	1.6	1.7	0.5	2.5	2.6	1.2	1.9	0.6	1.1	1.3	2.1	2.3	0.4	2.5	2.3	2.9	2.2	1.7	3.0	2.6	0.8
Number of self-reported non-cancer illnesses	3.4	6.0	14.7	1.9	2.9	0.6	2.1	0.1	2.0	2.8	1.0	1.8	0.5	2.8	0.7	3.2	3.3	0.0	3.8	3.2	3.2	3.4	2.0	3.0	3.8	-0.1
Stomach or abdominal pain in last month	3.2	3.9	7.9	2.3	2.2	1.0	2.0	1.4	2.6	1.8	1.3	1.0	1.8	2.2	2.1	1.3	2.3	0.6	1.9	2.8	2.4	2.0	2.3	2.3	2.7	1.3
Medication: Simvastatin	3.2	4.7	10.8	2.5	2.6	0.5	1.9	1.7	2.5	3.3	2.2	1.1	0.7	2.1	1.7	2.3	2.5	0.5	2.7	1.8	2.6	2.5	2.0	2.5	2.9	1.4
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.5	9.0	-2.3	-1.8	-0.2	-2.3	-2.2	-2.2	-1.6	-3.0	-0.5	-0.7	-1.8	-2.4	-1.0	-2.3	-0.7	-1.5	-2.2	-2.1	-1.8	-1.9	-1.8	-2.4	-1.8
Heart disease (mother)	3.1	3.7	8.1	-2.9	-1.8	-2.0	-1.4	-1.9	-2.4	-1.7	-1.9	-1.6	-2.7	-2.3	-2.5	-0.5	-1.8	-2.2	-0.7	-0.7	-1.8	-1.9	-1.8	-1.7	-1.7	-2.4
Birth weight of first child	3.0	5.4	10.6	3.0	2.6	1.2	1.8	2.3	3.1	2.9	2.5	1.7	3.2	2.6	2.7	0.7	2.4	0.8	1.8	2.0	2.7	2.3	1.5	2.8	2.1	2.3
Depression (Nagel 2018)	2.8	4.2	9.4	1.7	2.2	1.8	0.8	1.2	2.3	1.6	1.4	1.8	2.8	2.4	2.8	2.7	1.4	1.6	3.1	1.7	1.6	1.8	2.5	1.6	2.9	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.8	11.9	2.5	3.4	2.1	2.5	2.2	3.3	3.0	3.1	2.0	1.4	1.4	2.1	0.0	2.4	2.4	0.2	0.5	3.2	2.1	3.2	3.5	2.7	1.6
Unable to work because of sickness or disability	2.5	3.2	8.1	1.9	1.9	2.6	-0.4	2.8	2.1	1.2	2.1	2.6	2.8	1.2	1.9	-0.6	1.1	2.6	-0.7	-0.7	1.4	1.0	0.3	1.6	0.7	2.5
Cardiovascular Disease	2.3	7.7	17.5	2.5	3.4	-0.1	3.2	0.1	2.5	4.1	1.7	0.1	-2.4	1.9	-0.0	3.4	3.9	-0.3	3.1	3.0	4.2	3.7	2.5	4.1	3.6	1.1
Average weekly spirits intake	2.3	2.9	14.0	-1.4	-1.5	-1.6	-1.6	-1.5	-2.0	-1.0	-1.6	-3.7	-2.4	-1.3	-2.2	1.5	-1.1	-2.1	0.4	-1.1	-1.4	-0.7	-0.8	-1.4	-1.2	-2.2
High blood pressure	2.3	6.5	13.8	1.9	3.0	0.0	3.2	-0.7	1.9	3.5	0.9	0.6	-2.4	1.9	-0.3	3.4	3.5	-0.7	3.7	2.6	3.5	3.6	2.6	3.4	3.5	-0.0
Hair/balding pattern: Pattern 2	2.3	2.9	6.1	-2.2	-2.2	-1.6	-0.5	-1.8	-2.3	-2.4	-1.6	-0.9	-1.5	-1.2	-1.3	-2.3	-1.6	-1.1	-1.3	-0.3	-2.2	-1.6	-0.3	-2.5	-1.4	-1.9
Had major operations	2.3	2.7	5.9	1.6	1.9	0.2	1.5	0.3	2.1	2.1	1.0	1.7	1.4	1.8	1.7	1.0	2.0	0.2	2.4	1.7	2.2	1.8	1.1	2.2	2.0	0.7
Hypertension (Self-reported)	2.3	6.3	14.0	1.6	2.6	-0.7	3.2	-1.3	1.6	3.5	0.4	0.3	-2.7	1.7	-0.7	3.3	3.4	-1.4	3.7	2.8	3.4	3.5	2.4	3.2	3.3	-0.4
Coronary Artery Disease (CAD)	2.2	2.6	8.0	-1.7	-1.3	-2.2	1.1	-2.6	-1.8	-0.4	-2.2	-1.8	-2.6	-0.5	-2.6	0.9	-0.8	-2.3	0.6	-0.8	-0.5	-0.3	-0.8	-0.7	-0.9	-2.8
Angina	2.2	2.8	7.2	-2.1	-1.6	-1.2	-1.7	-1.3	-1.9	-1.9	-1.8	-1.5	-1.2	-2.0	-1.2	-0.1	-2.1	-1.7	-0.4	-1.2	-2.0	-1.9	-2.7	-1.8	-1.8	-1.1
Eye problems/disorders: Cataract	2.2	2.6	5.5	-1.9	-2.2	-1.0	-1.4	-1.9	-2.3	-1.6	-1.6	-2.1	-1.7	-1.0	-1.9	-1.1	-1.5	-0.8	-1.7	-0.5	-1.9	-1.5	-1.1	-2.1	-1.8	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.7	6.7	1.6	1.5	0.1	0.7	0.8	1.9	2.0	0.9	1.3	1.7	1.8	1.7	2.6	1.6	0.1	2.4	2.3	1.8	1.5	1.8	1.6	2.4	0.9
Prospective memory result	2.1	2.6	5.8	2.3	1.4	0.5	1.4	1.6	1.6	1.9	1.2	-0.4	1.6	1.8	0.9	1.0	2.4	0.7	1.8	1.4	1.9	2.2	1.9	1.4	2.0	1.9
Number of incorrect matches in round	2.0	3.3	8.5	1.9	2.4	0.2	2.0	0.5	2.2	2.5	0.9	1.2	-0.1	1.4	0.5	1.4	2.5	-0.1	2.2	1.3	2.9	2.5	1.4	2.9	2.3	0.6
Primary Biliary Cirrhosis	1.9	2.7	8.5	-1.9	-1.0	-0.2	-1.6	-2.2	-1.8	-1.1	-1.7	-2.9	-2.3	-2.3	-2.2	0.7	-1.6	-1.4	0.4	-1.5	-1.2	-1.3	-1.7	-0.9	-1.3	-1.3
Waist circumference	1.9	6.8	15.7	3.1	3.1	1.9	1.8	1.6	2.7	3.3	2.5	0.9	1.7	3.4	1.8	4.0	3.0	1.2	3.4	1.3	2.9	3.6	2.2	2.7	3.3	1.3
Pain all over the body in last month	1.9	2.1	6.7	1.8	1.1	0.4	1.4	0.9	1.5	1.6	1.1	1.5	1.1	2.6	0.7	1.3	2.2	0.1	1.1	1.7	1.9	1.9	0.3	1.6	1.5	1.2
Glaucoma (self-reported)	1.8	2.1	6.4	2.1	1.2	1.2	1.6	1.8	1.8	1.4	1.5	1.4	2.5	1.1	2.0	-0.2	1.4	1.0	0.3	1.2	1.2	1.4	0.7	1.1	1.1	2.1
Mouth/teeth dental problems: Loose teeth	1.8	2.2	7.4	1.3	1.6	-0.1	1.0	1.6	1.5	1.3	1.9	1.7	2.7	1.6	2.2	2.1	0.6	1.1	1.3	1.2	0.9	1.5	1.0	1.0	1.5	-0.3
Angina (self-reported)	1.8	2.4	6.9	-2.0	-1.5	-0.9	-1.6	-1.2	-1.7	-1.9	-1.7	-1.3	-1.0	-1.9	-1.1	-0.4	-2.0	-1.4	-0.4	-1.0	-1.9	-1.8	-2.6	-1.7	-1.7	-0.8
Alcohol intake frequency.	1.8	4.3	10.8	2.5	1.9	2.6	1.7	2.1	2.2	2.0	2.4	1.1	3.3	2.4	2.5	0.5	2.0	2.5	1.2	1.0	1.7	2.1	2.0	1.4	1.9	2.4
Financial situation satisfaction	1.8	2.3	7.7	2.0	1.4	1.4	0.7	2.8	1.6	0.3	1.9	1.9	1.5	1.4	1.9	0.4	1.3	2.2	0.0	0.5	1.1	1.6	1.6	0.9	1.4	1.2
Type 2 Diabetes (T2D) (2012)	1.7	1.9	8.1	-0.9	-0.8	-1.4	1.9	-2.1	-1.5	-0.6	-0.8	-1.6	-2.8	0.7	-2.1	1.1	0.5	-2.2	1.8	0.1	-0.0	1.5	0.7	-0.6	0.5	-1.1
Medication: Amlodipine	1.7	2.4	9.2	0.7	1.7	-0.8	1.4	-1.1	1.1	1.9	0.1	0.7	-1.2	0.6	-0.6	1.4	2.1	-0.8	2.2	3.0	2.3	2.0	0.8	2.3	2.0	-0.2
Wheeze or whistling in the chest in last year	1.7	3.1	7.7	1.8	2.4	1.1	1.7	0.8	2.1	1.8	1.2	1.9	0.4	1.7	0.7	2.3	2.1	-0.0	2.2	1.9	2.6	1.7	0.6	2.8	2.2	0.8
Mood swings	1.7	3.1	6.7	1.7	2.2	1.0	2.0	0.7	2.2	2.3	0.9	0.4	1.0	1.7	1.4	0.7	2.2	0.9	1.0	2.0	2.5	1.9	2.5	2.5	2.6	1.0
Vascular/heart problems diagnosed by doctor	1.7	4.7	12.0	-1.5	-2.4	0.4	-2.6	0.7	-1.5	-2.9	-0.5	-0.2	2.4	-1.6	0.4	-3.3	-2.8	1.0	-3.5	-2.0	-2.9	-3.0	-1.7	-2.8	-2.9	0.2
Medication: Lansoprazole	1.6	1.8	3.8	1.5	1.3	1.1	1.0	0.6	1.3	1.1	1.0	1.5	1.1	1.6	1.0	1.5	1.6	0.6	1.9	1.5	1.4	1.8	1.3	1.2	1.9	1.1
Trunk predicted mass	1.6	9.0	16.7	3.8	4.0	2.3	3.0	3.0	3.7	4.1	3.5	1.7	1.8	2.2	2.0	3.2	3.4	2.0	1.8	0.9	3.9	3.5	2.8	4.0	3.4	1.5
Pulse rate, automated reading	1.6	5.1	9.6	3.0	2.2	2.3	1.6	2.8	2.7	2.2	2.6	2.5	3.0	3.1	2.5	-0.6	2.4	2.1	-0.0	0.2	2.2	2.3	1.0	2.0	1.7	2.9
Knee pain experienced in last month	1.6	2.5	5.0	2.0	1.4	1.4	2.2	1.5	1.6	2.1	1.7	-0.1	1.2	1.7	0.8	1.1	2.1	0.7	0.7	1.9	2.0	1.9	1.2	1.7	1.6	1.8
Heart attack/myocardial infarction (self-reported)	1.6	2.1	5.0	-1.6	-1.3	-0.5	-1.0	-1.7	-1.7	-1.2	-2.0	-0.7	-1.6	-1.9	-1.7	-1.2	-1.5	-0.7	-0.9	-1.3	-1.4	-1.4	-2.2	-1.2	-1.8	-1.1
Neuroticism (2016)	1.5	2.1	5.6	-2.0	-1.3	-0.7	-1.9	-1.6	-1.4	-0.6	-2.1	-0.1	-1.4	-1.8	-0.5	-1.5	-2.3	-0.7	-0.5	-0.9	-1.8	-2.4	-1.4	-1.3	-1.5	-1.2
Chronic bronchitis/emphysema (father)	1.5	1.7	3.9	1.4	0.9	1.4	1.3	0.9	1.4	0.9	1.6	-0.2	0.7	1.5	1.5	-1.9	1.7	0.8	-0.1	1.9	1.4	1.3	0.8	1.1	1.3	2.0
Weight	1.5	7.4	19.8	3.1	3.4	1.6	2.2	2.3	2.9	3.3	3.1	2.1	1.7	2.8	1.9	4.5	2.9	1.3	2.8	1.2	3.1	3.3	2.6	3.1	3.3	0.8
Trunk fat-free mass	1.5	8.8	16.2	3.7	4.0	2.3	3.0	3.0	3.6	4.0	3.5	1.7	1.8	2.1	2.0	3.2	3.4	2.1	1.7	0.8	3.8	3.5	2.9	3.9	3.4	1.5
Suffer from ‘nerves’	1.5	2.3	9.9	1.3	1.9	0.4	1.5	1.9	2.3	0.6	1.5	3.1	1.6	1.5	2.2	-1.6	0.7	1.1	-0.1	1.1	1.4	0.4	1.2	1.8	1.1	1.2
Leg pain on walking	1.5	1.9	5.3	1.4	1.2	-0.3	1.6	0.8	1.4	1.2	1.5	1.5	1.1	1.2	1.1	0.6	1.7	0.1	1.4	2.3	1.5	1.8	1.7	1.3	1.8	0.9
Illnesses of father: High blood pressure	1.5	1.8	7.8	-1.3	-0.4	-0.9	0.7	-2.1	-1.4	-0.3	-1.5	-0.3	-2.8	-0.6	-2.5	1.8	-0.2	-2.1	0.9	-0.8	-0.2	0.2	-0.6	-0.1	-0.3	-2.5
Arm fat-free mass (left)	1.5	7.8	17.7	3.4	3.7	2.0	2.7	2.8	3.2	3.8	3.3	1.8	1.8	2.0	1.7	4.2	3.1	1.5	2.1	0.7	3.5	3.3	2.4	3.6	3.2	0.9
Arm predicted mass (left)	1.5	7.6	19.3	3.3	3.7	2.0	2.5	2.7	3.2	3.7	3.2	1.7	1.8	1.9	1.7	4.4	3.0	1.5	2.2	0.7	3.5	3.2	2.2	3.6	3.1	0.8
Alcohol intake versus 10 years previously	1.4	2.1	5.4	1.3	1.7	1.5	-0.2	1.6	1.7	1.3	1.5	2.0	2.1	1.9	1.8	-0.4	1.0	2.3	-0.3	-0.2	1.2	1.0	1.9	1.3	1.2	1.0
Noisy workplace	1.4	1.7	5.9	1.4	1.7	1.7	0.6	1.7	1.3	2.4	1.8	0.7	1.2	0.5	1.2	-0.2	1.1	1.9	-0.1	-0.7	1.2	1.7	0.9	1.2	0.9	0.6
Mouth/teeth dental problems: Dentures	1.4	2.4	6.4	1.6	2.3	2.5	0.8	1.8	2.0	1.9	1.8	0.1	1.3	0.9	0.7	1.2	1.4	1.9	0.3	-0.4	2.1	1.3	0.5	2.4	1.1	1.2
Illnesses of mother	1.4	1.8	6.4	1.5	1.2	1.9	1.0	2.2	1.7	0.4	1.3	1.2	2.5	0.8	1.8	0.2	0.4	2.0	-0.4	-1.0	0.8	0.4	-0.0	1.0	0.4	1.9
Length of working week for main job	1.4	1.6	4.5	1.3	1.3	0.6	2.1	0.9	1.6	1.4	1.7	0.7	-0.5	0.6	0.9	0.3	1.3	0.4	0.2	1.5	1.6	1.0	1.0	1.7	1.5	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	5.2	1.3	1.9	1.5	1.8	1.4	1.5	1.5	1.4	1.8	0.8	1.3	0.6	-0.0	1.5	2.0	0.1	1.2	1.8	1.2	2.3	1.8	1.8	0.7
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	3.8	-1.8	-1.6	-1.3	-1.9	-1.4	-1.6	-1.5	-1.1	-0.9	-1.6	-1.3	-0.5	-1.9	-1.9	-0.4	-1.7	-1.5	-1.9	-1.7	-1.0	-1.7	-1.7	-1.2
Number of operations (self-reported)	1.4	2.1	5.5	0.9	2.1	1.9	0.3	0.4	1.5	2.3	0.5	1.6	2.0	1.6	1.0	1.1	1.4	1.0	1.5	1.1	1.8	1.6	1.0	1.9	1.6	-0.1
Number of treatments/medications taken	1.3	2.3	9.8	0.3	1.3	-0.5	1.1	-1.1	0.7	1.1	-0.5	2.3	-0.3	0.9	-0.4	3.0	1.4	-1.2	3.1	2.4	1.6	1.4	0.5	1.5	2.1	-0.8
Ever used hormone-replacement therapy (HRT)	1.3	1.7	5.5	-1.6	-0.8	-1.0	-0.6	-2.0	-1.5	-0.8	-1.7	-0.2	-2.0	-1.7	-2.4	0.5	-0.9	-1.4	0.6	-0.8	-0.8	-0.7	-1.0	-0.6	-0.7	-2.1
Medication for hormone replacement therapy	1.3	1.4	5.5	-1.2	-0.8	-1.0	0.1	-2.1	-1.4	-0.1	-1.9	-0.7	-2.1	-1.6	-2.3	0.9	-0.2	-1.5	0.5	0.3	-0.4	-0.2	0.5	-0.4	-0.2	-1.3
Number of live births	1.3	1.9	8.5	1.0	1.4	-0.0	0.7	-0.0	1.5	1.1	0.6	0.8	0.3	2.1	1.8	1.8	1.2	-0.1	2.9	2.1	1.4	1.4	0.1	1.4	1.9	0.2
Forced expiratory volume in 1-second (FEV1)	1.3	4.2	8.8	2.5	2.3	1.6	1.5	2.4	2.6	2.5	3.0	-0.2	1.5	1.0	1.9	-1.3	2.5	2.4	-1.1	1.1	2.6	2.0	2.4	2.5	2.0	1.8
Loud music exposure frequency	1.3	1.4	10.6	-0.6	-1.2	1.5	-0.6	-0.3	-0.9	-1.6	-0.7	-1.0	-0.5	-0.5	0.1	-3.3	-0.6	1.2	-1.8	0.7	-1.1	-0.7	-0.4	-1.4	-1.1	1.3
Birth weight	1.3	2.9	9.1	2.4	2.1	1.1	2.0	0.9	1.9	3.0	1.2	1.1	0.8	1.0	0.9	0.5	2.0	0.8	2.2	-0.3	2.2	2.2	1.4	2.2	1.8	1.7
Arm predicted mass (right)	1.3	6.6	15.8	3.2	3.4	2.1	2.2	2.9	3.0	3.4	3.2	1.4	1.6	1.9	1.6	4.0	2.8	1.5	2.0	0.4	3.2	3.0	1.9	3.2	2.7	0.9
Ever had bowel cancer screening	1.3	1.6	5.3	1.0	1.2	0.2	1.2	0.3	1.0	1.0	1.1	2.2	0.5	0.7	0.6	2.3	1.2	-0.9	2.0	1.6	1.3	1.4	0.9	1.3	1.7	0.2
Medication for cholesterol	1.3	2.0	7.8	-0.7	-0.9	0.9	-1.5	0.9	-0.7	-1.6	-0.1	0.5	1.3	-1.2	-0.2	-2.8	-1.5	0.9	-2.6	-2.1	-1.4	-1.5	-1.2	-1.1	-2.1	0.5
Whole body water mass	1.3	7.5	15.1	3.3	3.7	2.0	2.6	2.7	3.1	3.8	3.2	1.8	1.4	1.8	1.4	3.9	3.1	1.6	2.0	0.7	3.5	3.3	2.6	3.6	3.2	0.8
Hearing aid user	1.3	1.4	5.6	-1.1	-0.1	0.4	-2.1	0.3	-0.0	-0.5	-0.7	0.9	1.0	-0.3	1.3	-0.5	-2.4	1.3	-1.2	-1.8	-1.4	-2.1	-1.4	-0.7	-1.4	-0.5
Basal metabolic rate	1.3	7.2	15.3	3.2	3.6	2.0	2.4	2.6	3.1	3.6	3.2	1.8	1.5	2.0	1.6	3.9	3.0	1.5	2.0	0.6	3.4	3.2	2.5	3.5	3.1	0.9
Diastolic blood pressure, automated reading	1.3	4.1	8.6	2.4	2.3	0.8	1.5	1.4	2.3	2.5	2.2	2.5	-0.6	2.9	1.9	0.8	2.4	1.0	1.4	2.2	2.4	2.7	2.0	2.3	2.2	1.6
Ovarian Cancer	1.2	1.6	4.7	1.5	0.9	0.9	0.0	2.2	1.4	0.3	1.6	2.0	2.1	0.9	1.7	0.3	0.8	1.8	-0.6	1.6	0.8	0.8	0.8	0.7	0.9	1.4
Had other major operations	1.2	1.4	9.6	0.6	1.7	3.1	-0.4	1.3	1.0	0.8	0.8	1.0	1.5	1.3	0.7	1.0	0.4	2.2	0.3	0.1	0.8	0.9	0.8	1.0	1.0	-0.3
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	2.9	1.4	1.4	0.9	1.4	0.2	1.3	1.7	0.1	1.1	0.5	1.1	0.9	0.8	1.4	1.1	1.6	1.3	1.5	1.4	1.6	1.4	1.5	0.5
Heart attack	1.2	1.5	5.0	-1.3	-1.0	-0.4	-0.9	-1.3	-1.4	-0.9	-1.7	-0.8	-1.3	-1.8	-1.6	-0.9	-1.2	-0.6	-0.8	-1.3	-1.0	-1.2	-2.2	-0.8	-1.6	-1.0
Diabetes (self-reported)	1.2	1.9	5.3	2.0	0.3	0.9	2.2	0.1	0.9	1.0	0.7	0.9	1.4	2.1	1.7	0.3	1.8	0.1	1.6	1.7	0.9	2.1	1.0	0.2	1.3	2.3
Father’s age at death	1.2	1.5	8.1	0.9	1.6	2.9	0.4	1.4	1.3	0.7	1.1	0.9	1.5	1.1	1.1	-0.7	0.5	1.8	0.4	-1.4	1.0	0.6	1.1	1.3	0.8	1.5
Arm fat-free mass (right)	1.2	5.9	14.0	3.0	3.2	2.0	2.1	2.6	2.8	3.3	3.0	1.0	1.6	1.8	1.4	3.7	2.7	1.4	1.8	0.4	3.0	2.9	1.9	3.1	2.6	0.9
Whole body fat-free mass	1.2	7.1	13.8	3.2	3.6	2.1	2.6	2.5	3.0	3.7	3.1	1.6	1.4	1.8	1.4	3.7	3.0	1.6	2.0	0.6	3.4	3.2	2.5	3.5	3.1	0.9
Medication: Blood pressure	1.2	2.2	7.1	0.6	1.4	-0.9	1.6	-1.0	0.8	1.7	0.2	0.8	-1.8	1.3	0.1	2.5	1.6	-1.0	2.7	2.0	1.7	1.7	1.2	1.6	2.1	-0.8
Supplements: Fish oil (including cod liver oil)	1.2	1.5	4.1	-1.5	-1.0	0.3	-2.0	-0.8	-1.3	-1.0	-1.4	0.1	-0.8	-1.7	-0.5	0.2	-2.0	0.2	-0.2	-1.3	-1.7	-1.7	-1.0	-1.4	-1.5	-1.3
Ever depressed for a whole week	1.2	1.5	7.7	-1.4	-1.2	-1.0	-0.2	-2.4	-1.4	-0.3	-2.8	0.2	-1.1	-1.7	-1.5	-0.2	-0.9	-1.1	-0.0	1.3	-0.8	-0.9	-0.4	-0.7	-0.9	-1.4
Blood Red Count	1.1	11.0	62.1	3.3	2.5	1.6	0.6	3.1	3.6	2.1	3.1	4.5	5.7	7.9	5.8	-0.5	1.6	2.7	2.0	2.1	1.6	2.5	1.7	1.5	2.0	3.1
Blood White Count	1.1	8.5	15.0	3.6	3.1	1.4	1.9	1.6	3.9	2.8	2.0	1.9	3.8	3.7	3.8	1.2	3.1	0.5	3.2	3.5	3.2	3.2	2.9	3.0	3.6	2.6
Hearing difficulty/problems: Yes	1.1	1.7	4.3	1.1	1.5	1.1	1.1	0.6	1.2	2.1	0.8	2.0	0.8	1.3	1.2	1.4	1.0	1.9	1.6	1.6	1.1	1.5	0.8	1.2	1.3	0.5
Leg fat-free mass (left)	1.1	5.6	15.9	2.6	3.2	1.6	2.1	2.0	2.4	3.3	2.7	1.8	0.7	1.6	0.7	4.0	2.7	1.0	2.1	0.5	3.1	3.0	2.2	3.1	2.9	0.3
Hand grip strength (right)	1.1	2.9	6.7	2.0	2.0	1.2	1.0	1.4	2.3	2.5	2.6	1.6	1.6	1.3	1.4	0.8	2.0	0.9	-0.3	0.6	2.5	1.5	1.3	2.5	1.8	1.2
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	10.0	-1.0	-0.9	-1.1	-0.7	-1.6	-1.3	-0.2	-0.8	-0.8	-3.2	-1.0	-2.1	0.8	0.1	-1.9	0.3	0.1	-0.2	-0.2	-0.7	-0.4	-0.3	-1.0
Leg predicted mass (left)	1.1	5.8	15.6	2.7	3.3	1.7	2.1	2.1	2.5	3.3	2.8	1.9	0.8	1.6	0.9	4.0	2.7	1.1	2.0	0.4	3.1	2.9	2.3	3.2	2.9	0.3
Illnesses of siblings	1.1	1.5	6.8	1.1	0.4	-0.4	-0.0	2.6	1.4	-0.5	1.8	2.5	2.3	0.2	2.3	0.5	-0.1	0.8	-1.2	-0.6	0.1	-0.5	0.2	0.1	0.1	0.8
Pulse wave Arterial Stiffness index	1.1	1.2	4.0	1.0	1.7	0.9	-0.5	1.2	1.5	0.8	1.2	1.3	1.1	1.2	1.3	0.2	0.5	2.0	0.2	0.9	1.1	0.5	0.9	1.4	0.8	1.4
Neck or shoulder pain in last month	1.1	1.6	3.4	1.1	1.8	1.5	0.4	1.0	1.8	1.3	1.1	1.2	1.0	1.0	1.4	-0.4	1.3	0.8	0.6	1.7	1.7	1.1	1.0	1.8	1.6	0.9
Leg fat mass (right)	1.1	4.2	16.5	2.2	2.4	1.5	1.1	1.5	2.0	2.4	2.2	1.6	1.4	2.5	1.6	4.1	1.9	0.9	2.9	1.1	2.0	2.5	1.5	1.9	2.4	0.5
Number of full sisters	1.1	1.3	5.1	-0.5	-2.1	-2.3	-0.4	-0.3	-1.3	-0.8	-0.9	-0.4	-0.2	-0.7	-0.9	0.1	-0.5	-2.2	-0.1	-0.6	-1.2	-1.0	-1.8	-1.6	-1.5	-0.3
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.4	-1.4	-0.7	-1.1	0.1	-2.0	-1.2	-0.2	-1.8	-1.0	-2.1	-0.7	-1.6	0.2	-0.5	-1.9	0.6	-0.4	-0.5	-0.3	-0.3	-0.5	-0.6	-2.0
Pack years of smoking	1.1	1.6	5.6	-1.2	-1.3	-1.1	-0.6	-1.6	-1.6	-0.9	-1.6	-1.5	-0.9	-1.0	-2.4	0.6	-0.7	-1.9	-0.0	-1.3	-0.9	-0.8	-1.2	-0.9	-1.0	-1.9
Leg fat mass (left)	1.1	4.2	17.0	2.2	2.4	1.7	1.1	1.5	2.0	2.3	2.2	1.4	1.4	2.5	1.6	4.1	1.9	0.9	2.9	0.9	2.0	2.5	1.6	2.0	2.4	0.6
Bipolar Disorder (2011)	1.0	1.0	2.1	-1.3	-0.7	-0.3	-0.9	-1.3	-1.1	-1.2	-1.4	0.9	-0.1	-0.8	-1.0	-0.3	-1.4	-0.2	-0.4	-1.0	-1.1	-1.0	-1.1	-0.7	-1.3	-1.4
HbA1C	1.0	1.1	5.1	-0.8	-1.1	-1.2	-0.2	-0.8	-0.8	-1.1	-1.0	2.3	-0.3	0.2	0.3	0.8	-1.3	-1.4	0.5	-0.3	-1.1	-1.3	-1.6	-1.2	-0.9	-0.9
Respiratory disease	1.0	2.3	6.1	-2.2	-1.9	-1.1	-2.5	-0.9	-1.9	-2.3	-1.4	0.3	-0.8	-0.2	-0.8	-0.4	-1.7	-1.0	-0.8	0.8	-2.0	-2.0	-1.2	-2.0	-1.5	-1.7
Taking other prescription medications	1.0	1.6	6.2	0.7	0.9	-0.5	0.2	-0.4	0.7	1.0	0.2	2.5	0.5	1.5	0.3	1.4	1.7	-0.1	2.2	1.9	1.3	1.6	1.3	1.0	2.0	-0.1
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	6.0	0.5	0.8	1.9	-0.2	1.0	0.7	0.4	1.1	-0.3	-0.7	-0.9	0.3	-2.5	0.5	2.1	-1.7	-0.6	0.6	0.2	0.4	0.7	0.1	1.1
Trunk fat mass	1.0	4.5	16.7	2.3	2.4	1.3	1.1	1.7	2.0	2.0	2.4	2.4	1.3	2.7	1.6	4.1	1.9	0.8	2.7	1.0	2.0	2.6	2.0	1.9	2.6	0.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	5.6	-0.9	-1.0	-0.2	-1.1	0.5	-0.8	-1.4	-0.3	-1.3	0.3	-0.7	-0.3	-1.6	-1.4	0.9	-2.4	-1.7	-1.4	-1.5	-0.4	-1.2	-1.6	-0.6
Fluid intelligence score	1.0	2.0	4.3	-2.1	-1.5	-1.9	-1.0	-1.3	-1.7	-1.6	-1.3	0.1	-0.8	-1.5	-1.4	0.1	-1.7	-1.4	-1.4	-0.1	-1.6	-1.9	-1.3	-1.4	-1.2	-2.0
Time employed in main current job	1.0	1.2	3.6	1.3	1.3	0.4	1.1	0.8	1.5	1.8	1.0	1.9	0.6	1.0	1.2	0.6	0.8	0.9	0.3	0.3	1.3	0.9	0.3	1.5	0.8	1.6
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	10.2	1.1	0.5	0.1	0.4	1.6	1.0	0.6	1.1	2.2	3.2	1.6	1.6	1.7	0.8	0.8	0.5	0.9	0.5	0.8	1.8	0.2	1.2	1.1
Arm fat mass (right)	1.0	4.0	19.8	2.0	2.2	1.0	1.0	1.1	1.9	2.2	1.9	1.9	1.1	2.3	1.3	4.5	1.9	0.3	3.2	1.2	2.0	2.4	1.3	2.0	2.5	0.3
Illnesses of father: None of the above (group 1)	1.0	1.3	7.1	-0.1	-0.3	-0.3	-1.4	1.4	0.3	-1.2	0.2	1.8	2.7	-0.0	1.8	-1.2	-1.2	1.3	-1.4	-0.5	-1.0	-1.2	-0.2	-0.8	-0.7	0.3
Eye problems/disorders: Glaucoma	1.0	1.2	4.0	1.6	1.0	1.0	1.3	1.0	1.2	1.5	0.9	0.3	1.2	0.6	1.1	-0.3	1.2	0.6	0.3	1.1	1.2	1.2	0.6	1.1	0.8	2.0
Cholesterol lowering medication	1.0	1.5	5.2	1.2	1.2	0.1	0.6	0.4	1.2	1.7	1.2	-1.0	0.2	1.1	0.7	2.3	1.6	-0.2	1.5	0.7	1.7	1.2	1.1	1.5	1.9	0.3
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	4.0	0.8	0.8	0.2	0.4	-0.6	0.6	1.5	0.2	0.3	0.4	1.4	-0.1	1.7	1.2	-0.1	2.0	1.6	1.1	1.7	1.4	1.0	1.5	-0.2
BMI	0.9	5.1	23.1	2.3	2.9	1.6	1.0	0.7	2.1	2.7	1.8	0.5	1.1	2.0	1.0	4.8	2.5	0.3	3.9	0.5	2.7	3.1	1.2	2.7	2.8	0.7
Medication: Metformin	0.9	1.2	6.8	-0.3	-1.3	-1.7	0.6	-2.3	-1.0	-0.4	-1.8	-0.2	-0.9	0.1	-1.0	1.1	0.2	-2.6	1.5	0.8	-0.5	0.3	-0.6	-0.9	0.1	-0.3
Hip circumference	0.9	3.8	9.6	2.2	2.4	1.1	0.9	1.9	2.0	2.1	2.3	1.4	1.8	2.5	1.9	3.1	1.9	1.2	2.0	1.0	1.9	2.4	2.1	1.8	2.5	0.1
Depression (self-reported)	0.9	1.0	3.4	-0.2	0.9	-0.2	1.4	-1.0	-0.4	0.6	-0.5	1.3	-1.4	-0.0	-1.8	1.2	0.9	-0.6	1.2	-0.2	1.0	1.2	1.4	0.9	0.7	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	7.7	1.7	2.2	1.0	1.0	2.4	2.2	2.1	2.8	0.2	1.1	0.5	1.3	-1.3	1.8	2.4	-1.7	-0.0	2.2	1.3	2.1	2.3	1.5	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.8	0.7	0.8	1.0	0.9	1.5	0.7	0.2	1.0	1.9	0.7	0.7	0.6	-1.6	0.9	1.8	-1.3	0.7	0.8	0.7	2.2	0.6	0.6	0.3
Whole body fat mass	0.9	3.7	17.1	2.0	2.1	1.2	1.0	1.4	1.8	1.9	2.1	1.8	1.2	2.5	1.4	4.1	1.7	0.6	2.8	0.8	1.7	2.4	1.6	1.7	2.3	0.3
Comparative height size at age 10	0.9	4.7	13.2	2.5	3.2	2.0	1.4	3.6	3.0	1.8	3.6	2.0	0.8	0.9	1.9	0.2	1.8	2.9	-1.1	0.2	2.6	1.5	1.6	2.9	1.8	1.6
Overall health rating	0.9	1.9	4.7	1.6	0.8	1.0	1.4	0.6	0.8	1.1	0.9	0.9	1.7	2.2	0.8	1.8	1.8	0.5	2.2	2.0	1.0	2.1	0.9	0.5	1.7	0.9
Leg fat-free mass (right)	0.9	5.0	14.1	2.6	3.0	1.6	2.2	1.8	2.2	3.0	2.5	1.5	0.8	1.4	0.6	3.8	2.6	1.0	1.9	0.3	2.9	2.9	2.4	2.9	2.7	0.3
Leg predicted mass (right)	0.9	4.9	13.9	2.6	2.9	1.7	2.2	1.9	2.2	2.9	2.5	1.6	0.8	1.4	0.6	3.7	2.5	1.0	1.9	0.3	2.8	2.8	2.3	2.8	2.6	0.3
Guilty feelings	0.9	1.4	4.4	-1.7	-0.9	-0.6	-0.8	-1.3	-0.8	-0.7	-1.3	1.3	0.0	-1.4	-0.3	-0.8	-1.7	-0.9	-0.6	-0.6	-1.1	-2.1	-2.0	-0.7	-1.2	-1.3
Average weekly beer plus cider intake	0.9	1.3	3.1	1.6	1.0	-0.7	0.5	1.5	1.2	1.5	0.7	-0.1	1.6	1.8	-0.1	1.7	1.7	-0.5	-0.0	-0.8	1.6	1.3	0.7	1.4	1.0	-0.2
Pain experienced in last month	0.9	1.5	4.5	-1.3	-1.3	-2.1	-1.3	-0.8	-1.3	-0.7	-0.6	-1.3	-1.8	-1.2	-0.8	-0.4	-1.4	-0.9	-0.6	-1.1	-1.4	-1.4	-1.2	-1.3	-1.5	-0.9
Alzheimer’s Disease (in father)	0.8	0.9	5.4	1.1	0.2	-0.1	0.4	0.4	0.3	0.4	0.6	0.4	-0.7	1.6	0.0	0.4	1.2	0.2	0.9	2.3	0.6	1.3	0.6	0.2	0.7	1.8
Blood Eosinophil Count	0.8	6.3	18.0	3.2	2.7	2.9	0.5	2.7	3.4	1.8	2.7	1.7	2.0	3.0	3.5	-0.7	2.2	2.2	1.0	2.5	2.5	2.2	1.8	2.5	2.3	4.2
Height	0.8	15.9	34.8	4.6	4.5	2.9	4.8	5.9	4.3	3.5	5.6	4.9	3.3	3.4	3.7	0.7	3.8	4.9	-0.1	0.8	3.7	4.1	5.6	3.4	4.0	2.7
Waist Hip Ratio (WHR)	0.8	3.4	8.4	2.7	1.6	1.4	1.7	1.5	1.9	1.8	2.0	-1.0	0.9	2.8	1.6	0.0	2.6	1.5	1.1	0.5	2.0	2.5	1.7	1.5	2.1	2.9
Hypothyroidism (self reported)	0.8	1.8	3.5	-1.4	-1.8	-1.7	-1.0	-1.8	-1.6	-1.9	-1.5	-1.6	-1.1	-1.2	-1.5	0.0	-1.0	-1.5	-0.9	-0.7	-1.2	-1.4	-1.2	-1.3	-1.2	-1.1
Chronotype (morning person)	0.8	1.8	5.4	1.8	2.1	1.2	0.1	1.7	1.9	1.8	1.8	-0.4	1.0	0.1	0.5	1.0	1.3	0.4	0.1	-1.6	2.0	1.1	-0.2	2.3	0.8	0.9
Pack years adult smoking proportion	0.8	1.3	4.2	-1.0	-1.4	-0.9	-0.5	-1.4	-1.5	-0.9	-1.5	-1.4	-0.4	-0.7	-2.0	0.3	-0.6	-1.6	-0.2	-1.1	-0.9	-0.6	-1.0	-1.1	-1.0	-1.6
Maternal smoking around birth	0.8	1.2	6.1	-0.7	-0.5	-1.0	-1.3	-0.7	-0.5	-0.4	-0.9	-2.5	-1.0	-1.1	-1.2	-1.0	-0.5	-0.9	-1.5	-1.4	-0.2	-1.2	-1.8	0.0	-1.1	-0.7
High blood pressure (mother)	0.8	1.1	4.9	-0.6	-0.4	-1.5	0.7	-1.4	-1.1	0.7	-0.6	-0.8	-2.2	-0.2	-1.7	0.1	0.7	-1.5	1.0	1.1	0.1	0.7	0.7	-0.2	0.5	-1.7
Body mass index (BMI)	0.8	3.4	21.5	1.7	1.9	1.1	0.8	0.1	1.3	2.5	1.1	0.5	0.6	1.8	0.5	4.6	1.8	-0.2	3.5	0.8	1.9	2.4	1.0	1.8	2.3	0.0
Nervous feelings	0.8	1.5	7.1	0.4	0.8	1.4	1.0	1.4	1.3	-0.3	0.9	2.7	1.1	0.6	2.5	-1.9	-0.4	2.1	-0.7	0.4	0.1	-0.4	1.0	0.4	0.3	0.9
Standing height	0.8	8.3	24.2	3.3	3.3	0.9	3.0	4.9	3.6	1.8	4.6	3.7	2.5	2.2	3.1	-0.2	2.5	3.3	-1.5	0.8	2.8	2.2	3.7	2.9	2.5	1.8
High blood pressure (siblings)	0.8	1.2	5.8	-1.0	0.0	-0.2	-0.0	-2.1	-0.9	0.6	-1.1	-2.4	-2.4	-0.3	-1.9	-0.1	0.2	-0.8	1.2	0.7	0.2	0.5	-0.2	0.2	0.2	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.6	1.2	1.3	1.0	1.6	0.9	1.3	0.4	1.0	0.4	0.7	1.0	0.5	0.6	1.1	0.0	0.8	0.3	1.3	1.0	0.2	1.4	0.7	1.1
Medication: Blood pressure	0.8	1.4	4.2	0.8	0.8	-0.9	0.8	-0.8	0.6	0.8	-0.3	0.4	-1.3	0.5	-0.6	2.1	1.5	-1.7	1.9	2.0	1.4	1.4	-0.2	1.4	1.2	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.4	1.3	1.3	1.0	0.1	1.5	1.6	0.4	1.1	1.1	0.3	0.3	1.2	-0.1	0.8	1.4	-0.3	0.4	1.2	0.7	-0.1	1.3	0.8	1.2
Commuting to job workplace: Walk	0.8	0.8	3.6	-0.1	-0.9	-0.2	-0.2	0.2	-0.5	-1.8	-0.6	0.7	0.4	0.2	0.1	-1.5	-0.8	0.4	-1.9	-1.6	-1.0	-0.9	-0.4	-1.1	-1.1	-0.0
Arm fat mass (left)	0.8	3.1	21.4	1.6	1.7	0.5	0.8	0.7	1.4	1.9	1.4	1.6	0.8	2.0	0.9	4.6	1.5	-0.2	3.2	0.6	1.5	2.1	1.1	1.4	2.2	-0.2
Wears glasses or contact lenses	0.8	0.9	6.2	0.6	1.5	0.3	0.7	0.4	0.9	0.6	0.1	-0.1	0.5	-0.0	0.7	2.5	0.4	0.4	1.8	0.7	0.8	0.7	0.5	1.0	1.5	-0.8
Medication: Bendroflumethiazide	0.8	1.3	4.0	1.0	1.1	-0.5	1.5	-0.1	1.3	1.5	0.9	0.9	-0.5	1.3	0.8	-0.1	1.5	-0.2	1.0	2.0	1.6	1.5	0.6	1.5	1.2	0.6
Bipolar Disorder (2018)	0.7	1.1	3.2	-1.3	-0.5	-0.0	-0.8	-1.3	-0.8	-1.7	-1.5	-0.5	-1.3	-1.0	-1.4	-0.4	-1.0	-1.2	-0.8	-0.4	-0.6	-1.2	-1.8	-0.2	-1.2	-0.9
Worry (Nagel 2018)	0.7	1.5	8.1	0.7	1.4	0.4	1.0	1.9	1.7	-0.1	1.3	2.9	1.0	0.6	2.2	-1.7	0.1	1.4	-0.8	0.1	0.8	-0.3	0.9	1.2	0.7	0.4
Major Depression (MDD)	0.7	0.9	3.5	-1.1	-0.5	0.0	-0.7	-0.3	-0.9	-0.4	-1.1	-0.6	-1.5	-1.8	-1.1	-0.4	-1.1	0.0	-0.2	-0.9	-1.0	-0.9	-1.9	-0.7	-1.3	-0.0
Body Mass Index (BMI) (2010)	0.7	0.9	3.6	0.9	0.1	-0.6	0.6	-0.3	0.3	1.1	0.1	-0.7	0.2	1.3	0.6	1.7	1.3	-0.7	1.9	0.2	0.6	1.5	1.6	0.2	1.4	-0.4
Ever had hysterectomy (womb removed)	0.7	0.8	2.9	-1.0	-0.5	-0.5	-1.1	-1.5	-0.9	-0.4	-1.1	-1.7	-1.1	-0.5	-1.6	1.0	-0.6	-1.2	0.6	0.6	-0.3	-0.5	-0.6	-0.1	-0.6	-0.2
Fed-up feelings	0.7	1.2	5.3	0.8	0.8	-0.2	0.4	1.2	1.3	0.4	0.8	1.9	1.8	1.1	1.9	-0.1	0.8	0.4	-0.0	2.3	0.8	0.4	1.1	0.7	1.4	0.7
Qualifications: CSEs or equivalent	0.7	0.9	5.9	0.3	-1.5	-0.8	-0.3	-0.6	-0.3	-0.3	-1.0	-2.4	0.6	0.3	0.3	-2.3	0.7	-1.1	-0.6	0.2	-0.3	-0.1	-0.3	-0.9	-0.5	0.6
Medication: Atenolol	0.7	0.8	3.9	-0.5	0.5	-0.7	0.9	-1.2	0.1	0.1	-0.7	-2.0	-1.7	-0.5	-1.0	1.5	0.1	-1.5	0.8	0.3	0.6	-0.1	0.3	0.9	0.6	-1.0
Alcohol usually taken with meals	0.7	1.1	3.6	-1.2	-0.6	1.1	-1.1	-0.3	-0.8	-1.3	-0.5	0.1	-0.9	-1.6	-0.9	-1.9	-1.1	0.3	-1.8	-1.0	-0.8	-1.4	-0.3	-0.6	-1.1	0.3
Forced vital capacity (FVC)	0.7	2.6	5.1	1.8	1.7	1.2	0.8	1.6	2.0	1.9	2.3	-0.3	1.3	0.7	1.6	-1.8	1.9	2.2	-1.4	1.1	2.0	1.3	2.0	1.9	1.5	1.3
Happiness	0.7	0.9	3.0	1.1	1.0	1.0	0.7	1.7	1.0	0.5	0.9	1.7	0.1	0.3	1.1	0.7	0.7	0.8	0.3	0.2	0.7	0.8	1.6	0.6	1.3	0.3
Medication: Paracetamol	0.7	1.2	7.8	0.7	1.0	1.2	-0.1	0.6	1.1	1.1	0.6	0.2	1.0	0.0	0.9	2.8	0.7	0.2	1.7	2.1	1.0	0.6	0.6	1.1	1.4	0.1
Leg fat percentage (right)	0.7	2.6	11.8	1.5	1.6	1.2	0.3	0.9	1.4	1.7	1.6	1.1	1.0	2.5	1.4	3.4	1.3	0.7	2.7	1.2	1.3	1.9	1.1	1.2	2.0	0.4
Number of full brothers	0.7	0.9	3.4	0.6	0.8	0.1	0.7	-0.6	0.3	1.8	-0.3	0.0	-0.0	0.7	-1.0	0.9	1.4	-0.2	0.8	1.1	1.4	1.3	1.3	1.3	1.2	0.3
Pulse wave peak to peak time	0.7	0.8	3.2	-0.7	-1.5	-0.9	0.7	-0.9	-1.2	-0.6	-1.0	-1.0	-0.8	-0.9	-1.0	-0.1	-0.2	-1.8	-0.2	-0.7	-0.8	-0.3	-0.6	-1.2	-0.6	-1.2
Average weekly red wine intake	0.7	1.0	9.1	-0.1	1.1	3.0	-0.2	0.5	0.6	-0.5	0.1	0.7	0.0	0.5	0.8	-1.8	-0.8	2.3	-0.1	-0.2	-0.1	-0.5	0.6	0.4	-0.2	1.1
Asthma (self-reported)	0.7	1.5	4.2	-1.4	-1.6	-1.4	-1.0	-1.0	-1.9	-2.0	-1.4	0.6	-0.9	0.0	-1.2	0.6	-0.8	-1.1	0.1	0.9	-1.5	-0.7	-0.3	-1.8	-0.7	-1.8
Osteoporosis (self-reported)	0.7	0.8	2.0	-0.2	-0.1	-0.2	1.0	-0.9	-0.6	0.1	-0.3	1.4	-1.4	0.1	-1.4	1.4	1.0	-0.9	1.2	0.7	0.5	1.0	1.3	0.1	0.9	-1.3
Medication: Paracetamol	0.7	1.1	7.6	0.3	0.7	0.5	-0.4	-0.7	0.5	0.6	-0.4	-0.7	0.3	-0.2	0.1	2.8	0.6	-0.8	2.3	2.3	0.8	0.6	-0.0	0.9	1.1	-0.5
Medication: Lisinopril	0.7	1.0	3.5	0.4	0.5	-1.8	0.9	-0.9	0.5	0.9	-0.2	1.2	-1.9	0.0	-0.6	0.8	0.9	-1.9	0.7	1.2	1.2	0.4	-0.2	1.2	0.5	0.4
Alcohol drinker status: Never	0.7	0.8	3.8	0.8	0.7	0.4	0.6	0.2	0.7	1.0	0.7	-0.9	1.3	0.6	1.1	1.8	0.4	-0.2	1.9	-0.4	0.4	0.7	1.1	0.4	1.1	-0.1
Leg fat percentage (left)	0.7	2.6	12.4	1.6	1.6	1.7	0.4	0.9	1.4	1.5	1.5	0.8	1.1	2.4	1.4	3.5	1.3	0.8	2.7	1.0	1.2	1.9	1.2	1.1	1.9	0.6
Neuroticism (Nagel 2018)	0.6	1.4	6.3	0.8	1.7	1.1	0.8	0.8	1.8	0.6	0.5	2.5	1.1	0.5	2.0	-0.7	0.5	1.3	0.4	0.7	1.1	0.2	1.7	1.5	1.4	0.5
Allergy or Eczema	0.6	1.6	7.8	0.9	0.4	2.8	-0.0	2.0	0.7	0.5	1.1	1.2	2.2	1.0	1.8	-1.8	0.0	2.5	-1.1	0.1	-0.1	0.0	0.9	-0.2	0.4	0.9
Lung FEV1/FVC ratio	0.6	2.9	5.9	2.0	2.0	0.1	2.1	2.0	1.9	2.4	2.3	0.4	0.1	1.4	0.9	1.3	2.4	0.5	1.0	0.4	2.3	2.1	1.6	2.1	2.0	1.4
Current tobacco smoking	0.6	0.9	4.2	1.2	0.6	0.5	1.3	0.3	0.9	2.0	0.5	0.2	0.9	0.5	0.2	-1.3	1.5	-0.2	-0.1	0.7	1.3	1.3	0.4	1.1	0.5	1.2
Impedance of leg (left)	0.6	3.0	14.4	-0.9	-1.9	-0.6	-1.6	0.9	-0.8	-3.1	0.1	-0.2	1.1	0.1	1.3	-3.8	-1.9	0.9	-2.9	-0.3	-2.3	-2.0	-0.9	-2.4	-2.1	0.7
Arm fat percentage (right)	0.6	2.4	17.1	1.2	1.4	0.6	0.2	0.3	1.1	1.4	1.0	1.8	0.6	1.9	0.9	4.1	1.1	-0.2	3.1	1.1	1.1	1.7	0.9	1.0	2.1	-0.1
Asthma	0.6	1.2	3.7	-1.2	-1.5	-1.3	-1.0	-0.8	-1.7	-1.9	-1.2	1.0	-0.9	0.1	-0.9	0.5	-0.8	-0.8	0.1	1.0	-1.4	-0.7	-0.2	-1.7	-0.6	-1.4
Impedance of arm (left)	0.6	2.9	11.6	-1.5	-2.0	-2.2	-1.8	0.3	-1.2	-3.1	-0.2	1.4	-0.4	-0.1	0.5	-3.4	-1.8	-0.1	-2.5	0.0	-2.1	-2.1	-0.5	-2.3	-1.6	-0.4
Breastfed as a baby	0.6	0.8	2.9	-1.4	-0.3	-1.1	-1.7	-0.2	-0.5	-1.0	-0.1	0.4	-1.0	-0.5	-0.2	0.4	-1.4	-0.2	-0.2	0.8	-0.8	-1.5	-1.3	-0.4	-0.6	-0.9
Peak expiratory flow (PEF)	0.6	1.5	3.8	1.5	1.5	0.7	0.6	1.1	1.6	1.5	1.9	-0.2	0.1	0.6	0.8	0.6	1.6	0.7	0.1	0.9	1.8	1.4	1.2	1.9	1.4	0.8
Gout (self-reported)	0.6	0.9	2.2	0.9	0.8	-0.2	0.3	0.5	1.2	0.6	0.6	1.2	-0.4	1.5	0.9	0.7	1.1	-0.6	0.8	1.4	1.3	0.8	-0.3	1.3	0.8	1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.7	0.4	0.8	0.5	-1.1	0.7	0.8	-0.1	0.5	1.4	1.3	1.6	1.5	1.2	0.0	1.2	0.5	1.0	0.3	0.0	0.6	0.4	0.9	0.0
Forced vital capacity (FVC), Best measure	0.6	2.1	4.8	1.5	1.8	0.7	0.8	1.8	1.9	1.7	2.2	0.1	1.3	0.5	1.3	-1.3	1.4	2.2	-1.6	0.1	1.8	1.0	1.8	1.9	1.2	0.9
Shortness of breath walking on level ground	0.6	0.7	2.0	-1.2	-0.7	-0.7	-1.1	-1.1	-1.2	-0.3	-1.2	1.1	-1.0	-1.2	-1.4	0.0	-0.5	-0.7	0.0	-0.3	-0.6	-0.5	-0.6	-0.6	-0.6	-0.9
Medication: Allopurinol	0.6	0.9	2.3	0.9	1.1	0.1	-0.2	1.0	1.2	0.5	1.1	1.1	-0.0	1.2	0.9	0.6	0.9	0.5	0.4	1.5	1.2	0.8	0.5	1.3	1.0	1.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.5	0.8	0.2	0.2	0.5	-0.1	0.6	1.6	0.3	-1.4	0.3	0.4	0.9	-0.6	1.1	-0.5	1.1	1.3	0.7	1.0	1.3	0.4	0.8	0.9
Arm fat percentage (left)	0.6	2.4	17.6	1.1	1.3	0.4	0.1	0.3	1.0	1.3	1.0	1.7	0.5	2.1	0.8	4.2	1.1	-0.3	3.2	0.8	1.1	1.8	0.8	0.9	1.9	-0.3
Long-standing illness, disability or infirmity	0.6	1.0	3.8	0.7	0.5	0.1	1.2	-0.4	0.3	1.1	0.2	0.9	0.6	1.3	-0.1	1.5	1.2	-0.4	1.9	1.0	0.8	1.5	1.1	0.5	1.5	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.5	-1.0	-0.6	0.3	-1.1	-1.1	-0.8	-0.1	-0.8	-1.5	-0.8	-0.9	-0.5	-0.5	-0.2	0.3	-0.1	1.6	-0.5	0.2	0.9	-0.7	-0.2	-0.5
Medication: Gliclazide	0.6	0.7	2.0	-0.3	-1.3	-0.3	0.2	-1.2	-1.0	-1.1	-1.4	0.1	-0.0	-0.0	-0.2	-0.6	-0.9	-0.5	-0.3	-0.7	-1.3	-0.5	-0.8	-1.4	-1.1	0.4
Commuting to job workplace: Public transport	0.6	0.7	3.5	-0.7	-0.3	-1.0	-0.6	0.5	-0.0	-1.0	0.2	1.1	0.3	-0.8	-0.2	0.5	-1.1	-0.4	-1.0	-1.0	-0.5	-1.4	-1.9	-0.1	-1.0	-0.3
Fractured/broken bones in last 5 years	0.6	0.8	3.3	-0.5	-0.9	-1.1	-1.8	0.3	-0.5	-0.9	-0.2	1.0	0.6	0.2	0.5	-0.5	-1.1	-0.5	-1.1	-0.7	-1.1	-1.1	-1.1	-1.0	-1.1	-0.2
Impedance of whole body	0.6	3.3	12.8	-1.4	-2.1	-1.6	-1.8	0.6	-1.1	-3.5	-0.1	1.0	0.4	-0.1	0.9	-3.6	-2.1	0.3	-2.8	-0.2	-2.5	-2.3	-0.8	-2.6	-1.9	0.0
Depressed Affect (Nagel 2018)	0.5	1.0	4.6	0.6	1.1	1.4	0.1	0.4	1.2	0.6	0.1	1.1	1.2	0.8	1.4	0.2	0.7	1.3	0.7	1.2	0.9	0.4	2.1	0.9	1.4	0.6
Reaction Time	0.5	0.9	3.2	0.8	1.1	-0.3	-0.4	0.5	0.9	1.4	0.5	1.2	-0.6	0.7	0.2	1.8	1.0	-0.1	1.4	0.2	1.2	1.0	1.0	1.2	1.3	0.1
Prostate Cancer	0.5	0.6	1.9	-0.8	-0.0	-1.0	-0.4	0.1	-0.2	-1.1	-0.5	0.9	-1.4	-1.0	-0.3	-1.2	-1.0	-0.1	-1.1	-1.2	-0.5	-1.3	-0.2	-0.1	-0.7	-0.3
Mean Putamen Volume	0.5	0.6	3.0	0.7	0.3	0.2	-0.1	0.7	0.5	0.2	0.6	0.8	0.6	0.9	0.8	0.7	0.7	0.3	0.3	1.4	0.4	0.9	1.7	0.1	1.1	0.4
HDL Cholesterol	0.5	0.8	4.1	-0.4	-0.1	-0.5	2.0	-0.8	-0.5	0.5	-0.5	0.4	-1.6	-0.2	-1.3	1.1	0.7	-1.4	1.0	0.5	0.4	0.7	0.0	0.2	0.5	-1.2
LDL Cholesterol	0.5	0.8	3.4	0.5	0.5	-0.8	0.7	-0.9	0.5	0.8	-0.3	0.7	-1.4	1.0	-0.2	1.1	0.9	-1.1	1.5	1.9	1.0	0.5	-0.0	1.0	0.8	0.3
Ulcerative Colitis	0.5	0.8	3.1	-0.6	-1.0	0.7	-0.7	-0.5	-0.9	-1.4	-0.7	0.2	0.1	0.2	0.8	0.3	-1.6	0.9	0.4	-0.6	-1.8	-0.8	-0.3	-1.8	-0.8	-0.4
Systolic Blood Pressure	0.5	2.3	11.8	0.4	0.5	-1.9	1.7	-1.8	0.2	1.1	0.1	-0.1	-3.4	1.2	-0.8	0.9	1.9	-1.5	1.7	2.9	1.6	1.6	0.8	1.2	1.4	-0.3
Lung FVC	0.5	2.5	6.2	1.8	2.2	1.6	0.5	1.2	2.5	2.0	2.0	0.0	1.4	0.9	2.1	0.2	1.6	1.4	0.8	0.9	2.2	1.3	1.1	2.4	1.9	1.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	4.2	0.2	1.1	1.1	0.8	0.6	0.5	0.9	0.5	2.0	0.5	0.8	0.1	0.4	0.5	1.2	-0.2	0.8	0.7	0.6	0.7	0.8	0.8	0.5
Supplements: Zinc	0.5	0.6	3.6	-0.2	0.9	1.5	0.8	-0.5	-0.2	0.6	0.1	-0.7	-0.5	-0.6	-1.9	-0.0	0.6	0.0	0.4	-1.2	0.9	0.7	0.5	1.0	0.2	-0.6
Diabetes (mother)	0.5	0.7	3.1	-0.6	-1.0	-1.6	-1.8	-0.9	-0.8	-0.3	-0.8	-0.9	-1.0	-0.1	-0.0	0.3	-0.6	-0.8	-0.6	0.6	-0.8	-0.4	0.2	-0.9	-0.3	-0.9
Impedance of leg (right)	0.5	2.4	13.9	-0.9	-1.6	-0.9	-1.6	1.0	-0.5	-2.5	0.3	0.2	0.9	0.3	1.3	-3.7	-1.5	0.8	-2.7	0.1	-1.8	-1.8	-1.0	-1.9	-1.8	0.6
Trunk fat percentage	0.5	2.2	13.1	1.2	1.5	0.7	0.1	1.0	1.1	1.0	1.6	2.0	0.8	2.2	1.0	3.6	1.0	0.2	2.5	0.7	1.0	1.7	1.2	0.9	1.8	-0.0
Hayfever, allergic rhinitis or eczema	0.5	1.0	4.4	0.2	0.5	1.9	-0.4	2.0	0.5	-0.1	0.9	0.6	1.4	0.2	1.1	-1.5	-0.5	2.1	-1.8	-0.4	-0.2	-0.5	0.6	-0.1	0.0	-0.0
Supplements: Glucosamine	0.5	0.6	2.6	-0.8	-0.8	-0.0	0.2	-1.6	-1.2	-0.3	-1.1	0.8	-0.9	-0.4	-0.8	-0.6	-0.9	-0.0	0.7	-0.8	-1.0	-0.3	-0.8	-1.0	-0.7	-0.6
Impedance of arm (right)	0.5	2.3	10.6	-1.5	-1.7	-1.8	-1.0	-0.1	-1.2	-2.8	-0.3	1.7	-0.5	-0.4	0.2	-3.2	-1.5	-0.0	-2.1	0.5	-1.9	-1.7	-0.1	-2.0	-1.2	-0.4
Medication: Cholesterol lowering	0.5	0.8	2.8	0.9	1.1	-0.4	0.6	0.1	1.1	0.9	0.1	1.7	0.0	0.5	0.5	0.6	0.9	-0.4	1.2	1.1	1.2	0.8	-0.1	1.4	0.9	0.8
Lung cancer (father)	0.5	0.6	2.2	-0.9	-0.2	-1.1	-0.3	0.2	-0.3	-0.3	-0.1	0.6	-0.5	-1.0	-0.3	0.1	-1.0	-1.0	-1.2	-0.9	-0.4	-1.1	-1.5	0.0	-0.8	-1.0
Tense / ‘highly strung’	0.5	0.9	2.8	0.4	1.5	0.2	1.2	0.3	1.1	0.8	0.5	1.7	-0.5	0.4	0.1	-0.5	1.0	0.1	-0.0	0.3	1.5	0.7	1.6	1.7	1.3	-0.5
Hair/balding pattern: Pattern 4	0.5	1.1	3.4	1.4	1.3	1.1	0.4	0.3	0.9	0.7	0.5	0.6	1.3	1.2	0.1	0.3	1.4	0.8	1.2	0.5	1.3	1.6	1.8	1.1	1.1	1.0
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.1	-0.5	-1.1	0.8	0.0	0.3	-0.9	-0.7	0.2	-1.4	0.8	-0.2	0.1	-1.3	-0.8	0.9	-1.3	-1.5	-1.2	-0.9	0.3	-1.4	-0.9	-0.2
Body fat percentage	0.5	2.1	13.0	1.3	1.4	0.8	0.1	0.8	1.1	1.1	1.4	1.6	0.9	2.2	1.2	3.6	1.0	0.1	2.7	0.9	0.9	1.7	1.1	0.9	1.8	0.1
Comparative body size at age 10	0.5	1.4	4.1	-1.1	-1.1	0.8	-1.0	-1.9	-1.5	-0.7	-1.7	-1.4	-2.0	-1.5	-1.9	0.0	-1.1	-0.7	0.5	-0.6	-1.0	-0.8	-1.0	-0.9	-1.3	-0.4
Medication: Seretide 50 evohaler	0.5	0.6	1.7	-1.0	-1.0	-0.4	-1.3	-0.6	-0.8	-1.0	-0.6	1.2	-0.9	-0.4	-0.0	0.2	-0.8	-0.6	0.1	0.9	-0.9	-1.0	-0.7	-0.9	-0.3	0.1
Illnesses of father: Heart disease	0.5	0.8	4.1	-0.0	0.2	-0.4	0.8	-0.9	-0.5	1.3	-0.1	-1.3	-1.8	-0.3	-2.0	0.1	0.8	-0.9	0.1	-1.0	0.8	0.9	-0.1	0.7	-0.3	-0.3
Breast cancer (self-reported)	0.5	0.6	2.1	-0.3	0.9	1.0	1.1	-0.3	0.1	0.5	0.6	0.9	-1.5	1.0	-0.2	1.2	0.1	0.6	1.2	0.9	0.3	0.8	0.1	0.5	0.8	-0.6
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.6	1.0	0.1	0.1	1.0	1.2	0.1	0.0	1.0	-1.2	0.5	0.5	-0.0	0.8	1.3	0.1	-0.3	1.2	0.5	1.2	1.2	0.0	1.0	0.6
High cholesterol (Self-reported)	0.5	0.8	3.1	0.6	1.1	0.1	0.0	0.5	1.0	1.4	0.8	-1.0	-0.6	0.1	-0.6	1.0	1.3	-1.0	0.5	0.4	1.7	0.6	0.2	1.8	0.9	0.5
Age started oral contraceptive pill	0.5	0.6	3.9	-0.6	-0.5	-0.7	0.0	-0.0	-0.4	-0.5	0.3	0.3	0.2	-0.4	-0.1	2.0	-0.7	-1.2	1.0	0.0	-0.5	-1.0	-1.8	-0.4	-0.4	-0.7
Alzheimer’s Disease (including proxy)	0.4	0.5	2.9	0.5	0.7	0.1	-1.1	0.5	0.5	0.9	0.4	-0.0	-1.1	0.8	-0.0	1.7	0.5	0.1	1.0	0.7	0.7	0.6	0.0	0.8	0.5	0.5
Irritable Bowel Disease (IBD)	0.4	1.0	2.9	-0.9	-1.2	0.7	-1.1	-1.5	-1.2	-0.8	-0.9	0.6	0.1	0.0	0.2	-0.3	-1.5	-0.1	0.3	-0.9	-1.7	-0.6	-0.8	-1.7	-1.1	-1.2
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.2	-1.5	-0.9	-1.0	-0.7	-0.6	-1.1	-0.7	-0.8	0.6	-0.6	-1.2	-0.8	-1.0	-1.3	0.1	-1.3	0.3	-1.1	-1.4	-0.8	-0.9	-1.0	-1.1
Blood Platelet Count	0.4	4.1	15.8	-2.1	-1.3	-0.6	-1.4	-4.0	-1.7	-0.5	-3.2	-3.4	-3.1	-2.1	-2.6	-0.4	-1.3	-2.8	1.0	-0.4	-0.8	-1.4	-2.8	-0.5	-1.4	-0.6
Hand grip strength (left)	0.4	1.1	2.7	1.4	1.2	0.5	0.8	0.9	1.4	1.5	1.6	0.5	1.0	0.7	0.8	1.0	1.5	0.2	0.1	0.3	1.6	0.9	0.8	1.6	1.2	0.2
Medication: Co-codamol	0.4	0.5	1.5	0.2	0.6	0.7	1.1	-0.3	0.1	1.1	-0.6	1.2	0.7	0.5	-0.5	0.2	0.6	0.8	0.3	-0.1	0.5	0.9	1.1	0.4	0.8	-0.3
Average weekly fortified wine intake	0.4	0.5	2.8	-0.6	-0.2	0.1	-0.0	-0.5	-0.6	-0.5	-0.9	-0.5	-0.6	-0.7	-0.5	-0.9	-0.9	0.5	-0.3	-1.7	-0.8	-0.4	1.0	-0.7	-0.4	-0.2
Age when periods started (menarche)	0.4	0.9	2.2	-1.1	-0.8	-1.4	-0.4	-0.5	-1.1	-1.3	-0.7	-1.5	-0.1	-0.2	-1.1	-1.3	-0.9	-0.9	-0.7	-1.0	-1.0	-0.8	-0.4	-1.0	-1.0	-1.2
Medication: Levothyroxine sodium	0.4	0.7	3.0	-1.0	-0.8	-0.8	-0.9	-1.7	-1.0	-0.7	-1.1	-0.7	-0.8	-0.6	-1.2	0.3	-0.6	-0.8	-0.1	-0.1	-0.6	-0.7	-0.8	-0.6	-0.5	-0.4
Past tobacco smoking	0.4	0.8	2.4	1.0	0.5	1.1	1.2	1.2	0.8	-0.7	0.7	0.9	1.3	1.2	1.3	-0.6	0.5	1.3	-0.3	-0.8	0.3	0.5	1.6	0.1	0.4	0.5
Hearing difficulty/problems with background noise	0.4	0.7	4.9	0.2	0.3	0.6	0.5	-0.2	0.2	0.7	0.4	2.2	0.1	0.8	0.6	0.1	0.7	1.0	1.1	2.2	0.4	0.7	0.4	0.2	0.7	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.4	0.6	1.0	-0.3	0.9	-0.4	0.6	1.1	0.6	2.1	-0.8	0.9	-0.5	-0.6	1.3	-0.2	0.4	1.0	1.3	1.4	1.2	1.3	1.0	0.2
Financial difficulties in last 2 years	0.4	0.5	3.1	0.3	0.6	-1.4	-0.5	1.5	0.4	0.4	0.8	1.8	0.8	0.3	0.5	1.4	-0.1	0.0	-0.0	0.2	0.1	0.3	-0.0	0.3	0.4	-0.6
Mouth/teeth dental problems	0.4	0.5	2.7	0.3	0.3	-1.4	0.1	-0.5	0.2	1.0	-0.1	-0.4	-1.6	0.3	-0.5	0.1	0.9	-1.3	0.6	0.8	0.9	0.4	-0.1	0.8	0.8	0.2
Worrier / anxious feelings	0.4	0.7	5.3	-0.6	-0.5	-0.4	-0.2	0.1	-0.0	-1.5	-0.2	1.0	0.4	-0.3	0.4	-2.3	-0.5	0.0	-1.9	0.7	-0.4	-1.1	-0.9	-0.3	-0.5	-0.1
Pulse wave reflection index	0.4	0.5	2.0	0.3	0.8	-0.3	-1.4	1.3	1.0	-0.3	1.0	0.3	-0.2	0.1	0.9	0.1	-0.2	1.0	-0.5	0.5	0.5	-0.7	-0.1	0.9	0.1	0.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.7	-0.5	-1.0	0.4	-0.2	-1.0	-0.8	-1.6	-0.8	-0.1	0.5	-0.3	0.1	-0.9	-0.6	-0.5	0.1	-0.4	-1.1	-0.2	0.4	-1.3	-0.6	-0.0
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.9	-0.8	-1.0	-1.6	-0.9	-1.7	-0.8	-0.9	-1.2	-0.5	-1.0	-0.5	-1.3	1.1	-0.1	-1.4	-0.0	0.1	-0.2	-0.7	-0.8	-0.3	-0.3	-0.8
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.2	0.6	0.9	-0.5	-0.3	1.1	0.9	0.4	0.7	1.5	1.4	0.8	1.2	0.4	0.1	0.5	0.4	-0.1	0.4	0.2	-0.3	0.6	0.5	-0.1
Age at first live birth	0.4	0.7	3.9	-0.3	-0.7	0.6	-0.6	0.2	-0.3	-1.3	0.3	0.3	0.0	-0.5	0.1	-1.9	-0.6	0.1	-2.0	-1.1	-0.6	-0.8	0.2	-0.6	-1.0	0.1
Health satisfaction	0.4	0.5	1.6	0.7	0.4	0.3	0.7	-0.0	0.5	0.6	0.1	1.0	0.6	0.7	0.3	1.3	0.9	-0.1	1.3	0.9	0.7	1.0	0.4	0.5	0.8	0.0
Emphysema/chronic bronchitis	0.4	0.4	1.6	0.0	1.2	1.2	-0.5	0.5	0.9	0.3	0.3	1.2	0.2	0.1	0.3	0.4	-0.3	0.7	0.2	-0.2	0.7	-0.4	0.2	1.2	0.4	0.5
Medication for pain relief, constipation, heartburn	0.4	0.6	1.4	-0.9	-1.1	-1.2	0.3	-1.1	-1.0	-0.6	-0.7	-0.3	-0.8	-0.2	-0.8	-1.1	-0.5	-0.9	-0.7	-1.0	-0.8	-0.6	-0.3	-0.9	-0.9	-0.3
Medication: Ibuprofen	0.4	0.5	2.2	0.1	0.3	1.1	0.9	-0.2	0.3	0.2	0.1	1.1	-0.1	0.9	0.5	-1.5	0.5	0.5	0.5	1.2	0.3	0.5	0.9	0.2	0.4	0.3
Family relationship satisfaction	0.4	0.5	2.6	0.4	0.6	0.5	0.5	1.6	0.6	0.5	0.9	0.8	0.6	-0.2	0.1	0.8	0.7	0.2	-0.7	-0.5	0.7	0.5	0.7	0.6	1.0	-0.4
Supplements: Vitamin C	0.4	0.4	1.8	0.3	0.6	1.2	-0.6	-0.3	0.3	1.1	0.4	-0.8	-0.0	-0.1	-1.3	0.4	0.7	0.2	-0.4	-0.2	1.1	0.5	0.4	1.2	0.2	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.1	-0.4	-0.7	-1.4	-0.3	-0.0	-0.3	-0.3	-0.0	0.2	1.4	-1.0	-0.4	0.7	-0.3	-1.0	-0.7	0.2	-0.4	-0.8	-0.9	-0.4	-0.3	-0.3
Smoking status: Current	0.4	0.6	3.4	0.9	0.3	-0.2	0.9	-0.2	0.6	1.8	0.1	-0.4	0.6	0.3	-0.1	-1.5	1.3	-0.7	-0.2	0.5	1.1	1.0	0.1	1.0	0.2	0.9
Risk taking	0.4	0.6	1.6	0.2	0.6	0.4	1.3	-0.8	-0.1	1.0	-0.4	-0.9	-1.0	0.4	-0.8	0.3	1.0	-0.3	0.9	0.9	0.8	1.1	0.9	0.7	0.9	-0.3
Myopia	0.4	0.5	2.6	-0.7	-0.3	1.1	-0.1	-0.0	-0.2	-1.3	-0.6	0.5	0.3	-0.5	-0.3	-1.6	-0.8	0.0	-1.1	-1.1	-0.4	-0.9	-0.5	-0.2	-0.7	-0.5
Schizophrenia (2018)	0.3	0.6	4.2	0.4	0.8	1.0	0.2	0.9	0.6	0.8	0.7	2.0	1.0	0.5	0.7	0.2	0.2	1.2	0.4	0.3	0.4	0.3	0.2	0.5	0.6	0.5
Alzheimer’s Disease (in mother)	0.3	0.3	1.9	-0.0	0.5	0.8	-1.1	-0.1	0.1	0.6	-0.2	-0.5	-0.9	-0.1	-0.7	0.8	-0.2	0.4	-0.0	-1.4	0.3	0.0	-0.3	0.7	-0.2	0.2
Crohns Disease (2017)	0.3	0.6	2.2	-1.0	-0.9	0.7	-0.6	-1.3	-1.1	-0.4	-0.6	0.1	-0.0	-0.1	-0.5	-0.6	-0.9	0.1	-0.5	-1.0	-1.1	-0.1	-0.3	-1.1	-0.8	-1.5
Age at First Birth	0.3	0.5	2.6	-0.2	-0.4	-0.3	0.4	0.9	0.1	-0.3	0.9	1.3	0.3	0.2	1.6	-1.0	-0.4	0.4	-0.5	1.4	-0.6	-0.5	-0.5	-0.7	-0.2	0.2
Fasting Glucose	0.3	0.3	1.1	-0.1	0.9	1.1	-0.6	-0.2	0.4	0.7	-0.5	0.4	-0.3	0.1	-0.6	0.9	0.3	0.3	0.8	0.3	0.7	0.3	0.5	1.0	0.7	-0.1
Lupus	0.3	0.5	2.2	0.8	0.1	0.7	0.7	0.7	0.5	0.4	0.6	-0.8	0.4	1.0	-0.2	-0.8	1.0	0.4	-0.9	0.7	0.8	0.4	0.5	0.6	0.2	1.5
Triglycerides	0.3	0.5	1.9	0.5	0.1	0.9	-1.4	0.6	0.5	-0.7	0.4	0.8	1.1	-0.0	0.9	-0.8	-0.2	1.0	-0.8	-0.5	-0.2	-0.4	0.0	-0.1	-0.5	1.3
Heel T-Score	0.3	2.7	9.9	1.8	0.9	0.6	1.3	1.7	2.0	0.9	1.7	1.3	1.8	2.1	3.1	-2.8	1.6	1.1	-0.6	2.0	1.2	0.9	1.5	0.8	1.3	1.5
Smoking Status	0.3	0.7	2.6	-0.1	-0.4	-0.5	0.3	-1.4	-0.3	1.6	-0.8	-1.0	-0.7	-0.6	-1.0	-0.6	0.6	-1.3	0.1	1.2	0.5	0.3	-1.3	0.4	-0.2	-0.0
Sensitivity / hurt feelings	0.3	0.6	2.0	-0.7	-0.2	-1.4	0.1	-1.2	-0.4	-0.6	-1.1	0.6	-1.0	-1.3	-0.9	0.5	-0.6	-1.2	0.3	0.0	-0.2	-0.8	-0.1	0.1	-0.1	-0.6
Systolic blood pressure, automated reading	0.3	1.0	9.4	-0.9	-0.3	-1.3	0.0	-1.9	-0.8	0.4	-0.8	0.3	-3.1	0.2	-1.0	0.1	-0.1	-1.4	0.9	0.9	-0.1	0.1	-0.7	-0.1	-0.2	-1.0
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.2	1.1	0.1	-0.7	0.4	0.7	0.7	-0.1	0.5	0.7	0.9	0.8	1.0	0.3	0.6	-0.5	0.5	-0.1	0.4	0.6	-0.2	0.2	0.1	0.5
Vitamin and mineral supplements	0.3	0.4	2.4	-0.6	0.1	-1.6	0.0	-0.5	-0.3	-0.0	-0.5	0.1	-0.1	-0.2	0.1	1.5	-0.2	-0.7	1.2	0.9	-0.2	-0.0	0.1	-0.2	0.7	-0.9
Diabetes (father)	0.3	0.3	3.2	0.3	-0.9	-0.2	0.6	0.7	-0.4	-0.4	0.1	-1.8	-0.0	0.5	0.3	0.2	0.1	-0.3	-0.4	-0.6	-0.5	-0.0	-0.1	-0.9	-0.5	0.1
Severe depression (siblings)	0.3	0.4	1.3	0.3	0.5	0.1	0.2	-0.3	0.4	0.5	-0.1	0.3	0.6	1.1	-0.2	0.1	0.9	-0.1	1.0	1.0	0.9	0.8	0.6	0.7	0.7	0.1
Townsend deprivation index at recruitment	0.3	0.4	1.4	0.8	-0.6	0.3	-0.1	1.2	0.1	0.2	0.6	0.9	1.1	0.5	0.6	-0.3	0.2	0.0	-1.0	0.2	-0.3	-0.0	-0.4	-0.5	-0.4	0.9
Relative age voice broke	0.3	0.4	2.2	0.3	0.0	-0.3	0.4	0.1	0.7	-0.1	0.4	-0.5	1.5	0.3	1.5	0.9	-0.3	-0.2	0.5	0.3	-0.0	-0.4	1.2	0.1	0.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.3	0.6	0.9	-0.6	0.8	-0.1	0.6	1.1	0.6	1.8	-1.2	0.2	-0.7	-0.9	1.2	-0.3	-0.4	0.1	1.4	0.8	0.2	1.4	0.5	-0.0
Multivitamins +/- minerals	0.3	0.4	1.7	0.7	-0.1	0.9	0.6	0.8	0.4	-0.0	0.6	0.7	0.3	0.5	0.7	-1.3	0.0	0.7	-1.0	-0.8	-0.1	-0.1	0.1	-0.1	-0.6	0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.8	0.0	0.4	1.3	-1.0	0.4	0.1	-0.2	0.4	-0.9	-0.0	0.1	0.3	0.3	-0.7	0.9	0.2	-1.1	-0.4	0.0	-1.3	-0.1	-0.5	-0.3
Sitting height	0.3	2.4	6.8	1.5	2.2	1.1	1.9	2.1	1.9	1.0	2.6	1.7	1.0	0.1	0.9	1.1	1.5	1.3	-0.6	0.6	2.0	1.2	1.8	2.2	1.6	-0.2
Had menopause	0.3	0.4	3.0	-0.2	0.5	0.5	0.9	-0.6	-0.0	0.8	-0.2	0.6	-1.7	0.3	-0.6	-0.4	0.6	-0.0	1.0	1.0	0.6	0.7	-0.4	0.6	0.3	0.1
Neuroticism score	0.3	0.6	3.0	0.3	0.9	0.1	1.1	0.7	1.1	0.1	0.2	1.7	0.5	0.4	1.3	-0.2	0.2	0.7	-0.2	1.0	0.6	-0.2	1.3	0.8	1.0	0.3
Pulse rate	0.3	0.5	2.9	0.7	-0.1	0.5	0.7	0.6	0.5	0.0	0.3	1.7	1.5	1.1	1.4	-0.5	0.6	0.3	0.0	0.6	0.0	0.4	0.1	-0.3	0.5	0.5
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.2	-1.2	-0.6	0.1	-0.5	-0.8	-0.6	0.1	-0.4	0.3	-1.0	-1.3	-0.2	-1.5	-1.2	-0.3	-1.2	0.2	-0.7	-1.4	-0.7	-0.4	-0.9	-0.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.5	-0.5	-0.3	0.5	0.2	-1.1	-0.7	0.1	-0.8	0.1	-1.1	-0.1	-0.8	-0.9	-0.1	-0.2	-0.3	-0.3	-0.3	0.2	1.2	-0.4	0.1	-0.9
Blood clot in the leg (DVT)	0.3	0.3	2.5	0.4	0.6	0.4	-0.5	0.3	0.4	0.8	0.4	0.6	1.0	0.2	0.1	1.6	0.1	0.3	0.8	-0.0	0.3	0.4	-0.7	0.4	0.2	-0.4
Exposure to tobacco smoke outside home	0.3	0.4	1.3	0.2	-0.9	-0.1	0.1	1.0	-0.2	-1.1	0.1	0.4	0.8	0.1	0.7	-0.0	-0.4	-0.1	-0.9	-0.1	-0.8	-0.6	-0.6	-1.0	-0.6	0.8
Medication: Omeprazole	0.3	0.3	1.7	0.0	-0.2	-0.8	-0.3	-0.5	0.0	0.3	-0.3	-0.1	0.8	0.8	0.3	0.8	-0.1	-0.1	1.0	1.3	-0.2	0.4	-0.1	-0.1	0.2	-0.6
Mean time to correctly identify matches	0.3	0.6	2.3	0.1	0.8	-0.7	-0.9	0.1	0.3	1.0	0.0	1.4	-0.8	0.1	-0.5	1.5	0.6	-0.9	1.1	-0.0	0.9	0.5	0.0	0.9	0.9	-0.4
Chest pain or discomfort	0.3	0.4	1.3	0.1	0.6	0.8	-0.5	1.1	0.6	0.1	1.0	0.4	-0.4	-0.6	0.0	0.3	-0.2	0.5	-0.4	0.8	0.4	-0.7	-0.5	0.7	-0.1	1.1
Smoking status: Previous	0.3	0.5	2.1	-0.7	-0.2	-0.1	-1.1	-0.9	-0.7	0.5	-0.4	-0.8	-1.4	-1.1	-1.3	1.0	-0.3	-0.4	0.2	0.5	-0.2	-0.2	-0.9	-0.0	-0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.8	0.7	0.5	0.9	0.5	1.2	0.4	-0.2	1.0	-0.2	0.2	-0.2	0.4	-1.3	0.7	1.4	-1.5	-0.2	0.4	0.5	1.7	0.2	0.4	0.8
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.5	-0.1	-0.7	-0.1	-0.1	0.5	-0.7	-1.2	-0.0	0.8	0.0	0.5	0.2	0.5	-0.4	0.1	0.0	0.6	-0.9	0.0	0.9	-1.1	-0.3	0.1
Diabetes diagnosed by doctor	0.3	0.5	1.4	0.7	-0.9	-0.3	1.1	-1.0	-0.5	-0.0	-0.7	-0.1	0.8	0.7	0.4	-0.1	0.7	-0.7	1.2	0.1	-0.3	1.1	0.0	-1.0	0.1	0.8
Qualifications: nursing, teaching	0.3	0.5	1.3	0.6	0.3	-0.1	1.1	-0.4	0.5	0.9	0.3	0.5	0.7	0.7	0.5	-0.3	0.9	-0.8	1.1	1.1	0.8	0.8	0.1	0.7	0.4	0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.0	-0.2	-0.7	-0.0	-0.6	0.8	-0.2	-1.3	0.4	0.8	1.4	0.3	1.1	-0.5	-0.6	0.9	-0.4	0.5	-1.0	-0.5	0.4	-1.1	-0.2	0.2
Back pain experienced in last month	0.3	0.4	1.9	-0.1	-0.3	1.4	0.6	-1.0	-0.7	-0.2	-0.8	-0.2	0.8	-0.5	-0.5	-0.3	-0.1	0.2	0.1	-0.5	-0.5	0.2	1.1	-0.7	0.1	-0.8
Mineral and other dietary supplements	0.3	0.3	1.0	0.6	0.4	-0.6	0.9	0.4	0.4	0.3	0.2	-0.0	0.7	1.0	0.1	0.2	1.0	-0.1	-0.1	0.2	0.7	1.0	0.9	0.4	0.8	-0.1
Mother’s age at death	0.3	0.3	1.1	-0.2	0.3	0.4	-0.6	0.2	0.5	-0.7	0.4	1.0	1.1	0.8	1.0	0.9	-0.8	0.1	0.3	0.4	-0.2	-0.5	-0.4	0.1	0.2	-0.4
Ever smoked	0.3	0.5	3.8	-0.5	-0.3	-1.4	-0.7	-0.5	-0.2	1.0	-0.2	-0.4	-0.9	-0.2	-0.2	0.4	-0.0	-1.4	0.4	1.9	0.1	-0.2	-1.0	0.2	0.0	0.1
Commuting to job workplace: Cycle	0.3	0.4	1.8	-0.3	-0.0	-0.8	-1.4	-0.7	-0.5	0.7	-0.4	-0.9	-0.4	-0.8	-1.2	1.1	-0.3	-0.2	-0.2	-0.6	-0.1	-0.1	0.3	0.0	-0.1	-0.2
Heart disease (siblings)	0.3	0.4	1.5	0.4	0.0	-0.8	0.6	0.1	0.2	0.3	0.6	-0.7	-0.5	1.2	0.2	0.9	0.7	-0.3	0.8	1.1	0.4	0.9	-0.4	0.1	0.4	0.3
Intelligence (Savage-Jansen 2018)	0.2	0.8	3.9	-1.3	-0.5	-1.4	-0.4	-0.1	-0.9	-0.3	-0.4	0.9	-0.8	-0.9	-0.7	0.6	-0.8	-0.5	-0.4	-0.4	-0.7	-1.1	-1.3	-0.6	-0.6	-2.0
Schizophrenia vs Biploar Disorder	0.2	0.3	1.2	-0.0	0.0	1.0	-0.2	1.0	0.2	0.2	0.5	0.0	1.1	0.2	0.7	0.2	-0.1	1.1	-0.2	0.6	-0.2	-0.2	0.2	-0.2	0.1	0.2
Ulcerative Colitis (UC)	0.2	0.3	1.1	-0.1	-0.5	0.9	-0.6	-1.0	-0.4	-0.4	-0.5	0.7	-0.2	0.5	0.6	-0.1	-0.7	0.1	0.9	-0.0	-0.9	-0.1	-0.1	-0.9	-0.4	-0.1
Breast Cancer	0.2	0.4	2.6	0.3	-0.3	-1.2	0.0	-0.4	-0.2	0.8	-0.1	1.6	-0.6	-0.5	-0.6	-0.7	0.7	-0.7	-0.7	0.5	0.4	0.6	-0.2	0.2	-0.3	0.8
Crohns Disease (2012)	0.2	0.3	1.7	-0.4	0.2	0.9	-0.7	-0.7	-0.2	-0.5	0.1	-0.2	0.6	0.4	0.0	0.5	-0.7	0.8	-0.4	-0.8	-0.4	-0.0	-0.2	-0.2	-0.1	-1.3
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.1	0.8	-0.2	-0.0	0.7	-0.3	-0.0	-0.0	0.3	0.4	0.9	0.7	0.5	0.2	0.9	-0.6	0.6	0.2	0.2	1.1	-0.2	-0.3	0.4	0.9
Relative age of first facial hair	0.2	0.5	1.4	0.9	0.5	-0.5	0.8	0.0	1.0	-0.1	0.4	0.9	0.9	0.4	1.2	0.7	0.4	-0.3	0.8	0.7	0.7	0.3	1.0	0.8	0.9	-0.0
Serious illness, injury or assault to yourself	0.2	0.3	3.5	-0.3	0.5	0.0	0.1	-0.1	-0.0	0.5	0.1	1.9	-0.8	0.1	-0.4	0.4	0.1	0.5	0.2	0.4	0.2	0.3	0.1	0.3	0.3	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.5	-0.3	0.2	0.9	0.2	0.5	0.2	0.3	-0.2	1.2	0.9	0.6	0.3	0.8	-0.1	0.6	-0.1	0.2	-0.0	-0.1	1.1	0.0	0.3	-0.4
Qualifications: None of the above	0.2	0.4	1.4	-0.3	-0.7	0.1	-0.2	-0.8	-0.6	0.2	-1.2	-1.0	0.9	-0.5	-0.8	1.0	-0.1	-0.9	0.6	-0.2	-0.3	-0.1	-0.3	-0.5	-0.1	-0.4
Allergy	0.2	0.5	2.0	0.2	-0.1	-1.1	1.2	-1.2	0.0	0.5	-0.4	-0.9	-0.9	-0.1	-0.6	0.7	0.6	-1.4	0.8	0.0	0.5	0.6	0.0	0.4	0.2	0.4
Falls in the last year	0.2	0.2	0.8	-0.5	0.4	0.5	-0.0	-0.4	-0.1	0.9	0.1	0.8	-0.9	-0.3	-0.7	0.4	0.2	-0.2	-0.0	0.6	0.6	0.3	0.0	0.8	0.4	-0.5
Hair/balding pattern: Pattern 3	0.2	0.3	1.4	-0.4	0.4	0.2	-0.3	-0.2	0.3	0.6	0.0	1.1	-0.8	-0.9	0.1	0.0	-0.4	0.1	-0.1	-0.3	0.2	-0.4	-1.2	0.6	-0.0	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	2.2	0.3	0.6	1.5	0.0	0.5	0.7	-0.2	0.4	0.2	0.6	0.4	0.8	-0.8	0.0	0.8	-0.0	-0.0	0.3	0.0	0.2	0.5	0.1	0.5
Headache pain in last month	0.2	0.3	2.0	0.2	0.4	0.8	-0.1	0.9	0.3	-0.0	0.5	0.3	1.4	0.4	0.7	-0.2	0.3	0.5	-0.1	1.4	0.2	0.3	0.7	0.1	0.5	0.1
Qualifications: College or University degree	0.2	0.5	1.9	-0.9	0.4	-0.5	0.1	0.6	-0.1	0.1	0.9	0.8	-0.9	-1.1	-0.4	-1.2	-0.6	0.4	-1.4	-0.0	-0.1	-0.9	0.1	0.3	-0.2	-0.8
Eye problems/disorders: None of the above	0.2	0.2	1.2	-0.7	0.2	0.1	0.5	-0.4	-0.1	-0.2	-0.0	0.6	-0.7	-0.6	-0.3	0.1	-0.3	-0.2	0.5	-0.7	0.0	-0.3	-0.1	0.2	0.2	-1.1
Migraine (self-reported)	0.2	0.2	1.4	-0.6	-0.4	-0.4	-1.2	-0.6	-0.5	-0.3	0.0	0.1	-0.3	-0.3	-0.3	-0.4	-0.3	-0.0	-0.1	-0.1	-0.3	-0.5	-0.9	-0.3	-0.3	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	2.1	-0.5	-0.4	0.7	-0.3	-0.0	-0.3	-0.5	-0.5	0.3	-0.9	-0.1	-0.2	-0.2	-0.6	-0.2	-0.1	-0.0	-0.4	-0.6	-1.4	-0.3	-0.8	0.6
Age at last live birth	0.2	0.3	1.7	-0.6	-0.5	-0.0	-0.6	0.1	-0.1	-1.3	0.3	0.1	-1.0	-0.3	0.2	-0.1	-0.3	-0.8	-0.5	0.4	-0.2	-0.7	-0.6	-0.2	-0.3	-0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.0	-0.4	-0.6	-0.5	-0.4	-0.6	-0.4	-0.5	-0.5	-1.0	-0.6	-0.6	0.0	0.1	-0.2	-0.8	0.6	-0.7	-0.3	-0.5	-0.4	-0.5	-0.3	-0.0
Medication: Aspirin	0.2	0.3	2.1	-0.3	0.1	-0.4	-0.8	-0.3	-0.5	-0.3	-0.6	-0.3	-1.1	-0.4	-0.8	0.5	-0.2	-0.0	0.4	-1.4	-0.2	-0.0	-0.4	-0.1	-0.3	-0.6
Illnesses of siblings: Diabetes	0.2	0.3	1.3	-0.1	-0.2	1.1	-0.3	-0.3	-0.4	0.3	-0.8	-1.1	0.3	-0.3	-0.8	-1.1	0.3	-0.1	-0.8	0.4	0.1	0.1	-0.4	-0.0	-0.4	-0.1
Osteoarthritis (self-reported)	0.2	0.3	1.1	-0.5	-0.3	0.2	-0.2	-0.8	-0.8	-0.4	-1.1	-0.2	-0.4	-0.1	-0.7	0.8	-0.4	-0.1	0.5	0.2	-0.5	0.0	-0.5	-0.6	-0.0	-0.8
Medication: Aspirin	0.2	0.2	1.4	-0.2	0.2	-0.4	-0.6	-0.3	-0.4	-0.3	-0.5	-0.2	-1.0	-0.3	-1.0	0.3	0.0	0.1	0.3	-1.2	0.0	0.2	-0.4	-0.0	-0.2	-0.3
Average weekly champagne plus white wine intake	0.2	0.3	0.8	0.5	0.5	-0.6	0.2	0.8	0.5	-0.8	0.8	0.3	-0.5	-0.2	-0.1	-0.0	0.8	0.2	-0.3	0.5	0.8	0.5	0.4	0.7	0.9	-0.4
Ever taken oral contraceptive pill	0.2	0.2	2.0	-0.0	0.5	0.2	-0.7	0.1	0.3	0.1	0.1	-0.9	0.0	-0.2	0.1	1.4	-0.3	0.6	0.1	0.7	0.1	0.3	-0.4	0.4	0.2	-0.3
Medication: Atorvastatin	0.2	0.3	2.1	-0.2	-0.6	-0.6	-0.2	-0.3	-0.2	-0.8	-0.3	-1.2	-0.1	0.1	0.1	0.4	-0.1	-0.6	-0.1	0.1	-0.2	-0.5	-1.5	-0.3	-0.2	-0.0
Irritability	0.2	0.3	2.0	-0.1	0.6	0.2	0.6	-0.0	0.4	0.3	-0.2	1.4	-0.8	-0.6	0.4	0.3	0.1	0.8	-0.1	0.1	0.3	0.3	1.3	0.4	0.4	-0.2
Basal cell carcinoma (self-reported)	0.2	0.2	2.1	-0.2	-0.1	-0.4	-0.0	0.3	-0.4	-0.6	0.1	-0.3	-0.4	-0.5	-0.5	-0.3	-0.3	0.1	-0.5	-1.4	-0.3	-0.3	-0.7	-0.3	-0.5	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	3.3	0.1	0.2	-0.1	-0.8	-0.0	0.0	0.4	0.0	0.4	0.6	-0.1	-0.3	1.8	-0.2	-0.2	0.8	-0.3	-0.0	-0.0	-1.0	0.1	-0.1	-0.7
Alcohol drinker status: Previous	0.2	0.2	0.9	0.2	0.6	1.0	0.4	0.3	0.6	0.4	0.5	0.3	0.5	-0.2	-0.3	0.6	0.2	0.3	-0.3	-0.2	0.7	0.0	-0.6	0.9	0.0	0.5
Bipolar Disorder or Schizophrenia	0.1	0.2	1.7	-0.5	0.3	0.8	-0.3	-0.1	-0.0	-0.5	-0.4	1.3	-0.0	-0.3	-0.3	-0.1	-0.5	0.2	-0.2	0.0	-0.1	-0.6	-1.0	0.2	-0.3	-0.2
Rheumatoid Arthritis	0.1	0.2	1.0	-0.2	0.2	0.2	-1.0	0.5	0.3	-0.5	-0.0	-0.3	0.3	0.1	0.7	-0.4	-0.4	0.3	-0.6	0.8	-0.1	-0.6	-0.7	0.1	-0.1	0.2
Schizophrenia (2014)	0.1	0.2	1.1	-0.1	0.6	0.7	0.3	-0.2	0.2	0.3	-0.1	1.1	0.1	0.0	-0.1	0.4	0.0	0.5	0.6	0.2	0.3	0.2	0.4	0.4	0.3	-0.2
Neuroticism	0.1	0.3	1.0	-0.2	0.5	0.4	0.6	0.4	0.5	-0.1	-0.2	1.0	0.2	-0.3	0.9	-0.3	-0.6	0.9	-0.5	0.1	-0.0	-0.7	0.6	0.3	0.2	0.0
Hair Pigment	0.1	1.9	6.2	-1.4	-1.2	0.5	-2.2	-1.2	-1.1	-1.2	-1.9	-0.5	-0.4	-1.0	-0.2	-1.1	-1.9	-0.7	-0.1	-1.8	-1.7	-1.9	-2.5	-1.4	-1.6	-0.7
Tanning	0.1	1.2	6.0	-0.6	-0.3	-2.0	0.7	-0.8	-1.0	0.6	-0.1	-0.5	-1.2	-1.4	-2.2	0.6	0.0	-1.4	-0.4	-2.4	-0.3	-0.5	-0.2	0.0	-0.8	-1.5
Medication: Ramipril	0.1	0.1	1.1	0.2	-0.3	-1.1	-0.3	-0.3	-0.3	-0.1	-0.5	0.2	0.1	-0.5	-0.6	-0.1	0.4	-0.4	0.3	0.0	-0.0	0.5	-0.3	-0.3	-0.3	0.2
Exposure to tobacco smoke at home	0.1	0.1	0.4	0.6	-0.1	0.6	-0.1	-0.0	0.2	-0.4	-0.4	-0.3	0.1	0.7	0.2	0.3	0.1	-0.4	0.5	-0.0	0.0	0.4	-0.4	0.0	-0.1	0.4
Worry too long after embarrassment	0.1	0.2	0.8	-0.3	0.0	0.2	0.9	-0.9	0.1	-0.5	-0.6	0.1	-0.2	-0.8	0.2	0.2	-0.5	0.3	0.5	0.9	-0.2	-0.5	0.1	-0.0	0.3	-0.0
Number of children fathered	0.1	0.1	0.7	-0.4	-0.2	0.4	-0.4	-0.8	-0.3	-0.1	-0.6	-0.1	0.6	0.1	-0.0	0.0	-0.4	0.2	0.2	-0.2	-0.4	-0.3	0.4	-0.4	-0.0	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	2.0	-0.4	-0.0	-0.2	-1.4	0.1	-0.1	-0.3	-0.1	0.1	-0.1	-0.3	-0.0	0.8	-0.5	0.1	-0.1	0.1	-0.2	-0.4	0.2	-0.1	0.2	-0.3
Friendships satisfaction	0.1	0.2	0.7	-0.0	-0.2	-0.1	0.6	0.4	-0.2	0.3	-0.2	-0.2	-0.7	-0.0	-0.2	-0.6	0.4	-0.0	-0.8	0.7	0.1	0.2	0.7	-0.2	0.3	0.1
Miserableness	0.1	0.2	1.8	-0.3	0.3	0.2	-0.5	-0.1	0.1	0.3	-0.4	-0.1	-0.2	-0.2	0.1	0.1	-0.0	0.1	-0.3	0.7	0.1	-0.3	1.4	0.2	0.5	-0.3
Supplements: Calcium	0.1	0.1	0.7	-0.1	-0.1	0.6	-0.3	-0.4	0.0	0.2	0.0	-0.7	0.2	-0.0	-0.5	-0.3	0.4	-0.3	0.1	0.5	0.3	0.0	-0.9	0.3	-0.4	-0.1

Hub : Genes

ARV1

Models

Trait associations