[Hub]/) : Traits : Systolic Blood Pressure :

chr11:116,352,008-117,800,682

Best TWAS P=3.18e-10 · Best GWAS P=3.08e-11 conditioned to 0.00443

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SIDT2 0.07 0.06 lasso 5 0.05 8.8e-07 5.8 -6.3 3.2e-10 -0.76 0.30 0.70 TRUE
2 GTEx Esophagus Muscularis PCSK7 0.18 0.09 lasso 3 0.10 9.2e-07 5.9 -5.1 2.9e-07 -0.72 0.47 0.52 FALSE
3 GTEx Pancreas SIDT2 0.17 0.12 lasso 3 0.08 1.9e-04 5.9 -5.4 7.5e-08 -0.73 0.23 0.43 FALSE
4 GTEx Testis TAGLN 0.15 0.05 lasso 5 0.04 8.0e-03 5.1 -5.6 2.5e-08 -0.79 0.26 0.30 FALSE
5 GTEx Whole Blood SIDT2 0.18 0.06 lasso 7 0.04 2.3e-04 5.9 -5.8 8.3e-09 -0.73 0.27 0.72 FALSE
6 METSIM Adipose SIDT2 0.09 0.07 lasso 7 0.07 2.3e-10 5.9 -5.4 7.6e-08 -0.67 0.29 0.71 FALSE
7 METSIM Adipose TAGLN 0.04 0.04 lasso 4 0.04 2.8e-06 5.9 -5.3 8.8e-08 -0.73 0.47 0.52 FALSE
8 NTR Blood SIDT2 0.12 0.15 lasso 4 0.15 2.3e-46 5.9 -5.4 7.8e-08 -0.73 0.29 0.71 FALSE
9 YFS Blood SIDT2 0.40 0.40 enet 46 0.46 1.3e-168 5.9 -5.4 6.5e-08 -0.73 0.28 0.72 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma SIDT2 0.11 0.00 blup 46 0.05 8.2e-04 5.9 -5.4 8.0e-08 -0.64 0.01 0.67 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PCSK7 0.04 0.03 lasso 3 0.03 5.6e-04 5.8 5.9 3.7e-09 0.76 0.01 0.99 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma SIDT2 0.08 0.01 blup 46 0.05 2.4e-06 5.1 -5.4 8.3e-08 -0.59 0.07 0.58 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma SIDT2 0.02 0.01 blup 46 0.01 4.6e-02 4.7 -5.3 1.1e-07 -0.76 0.02 0.64 FALSE