TWAS hub - SIDT2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0680	0.0210	6.8e-06	0.064	0.050	0.045	0.050	0.050	3.3e-08	1.0e-06	3.4e-06	1.0e-06	8.8e-07
2	GTEx	Lung	0.0759	0.0306	1.3e-03	0.077	NA	0.063	NA	0.068	1.6e-06	NA	1.4e-05	NA	6.8e-06
3	GTEx	Pancreas	0.1690	0.0610	2.3e-03	0.122	NA	0.065	NA	0.085	8.1e-06	NA	1.1e-03	NA	1.9e-04
4	GTEx	Skin Not Sun Exposed Suprapubic	0.1910	0.0950	7.6e-03	0.007	NA	0.009	NA	0.015	1.3e-01	NA	9.4e-02	NA	5.1e-02
5	GTEx	Skin Sun Exposed Lower leg	0.1090	0.0460	2.4e-03	-0.001	NA	0.006	NA	0.003	4.5e-01	NA	9.0e-02	NA	1.5e-01
6	GTEx	Testis	0.2310	0.0720	2.5e-05	0.011	NA	0.054	NA	0.048	1.1e-01	NA	2.0e-03	NA	3.4e-03
7	GTEx	Thyroid	0.0560	0.0270	8.7e-03	0.019	NA	0.002	NA	0.024	1.2e-02	NA	2.0e-01	NA	5.8e-03
8	GTEx	Whole Blood	0.1810	0.0570	3.9e-05	0.056	NA	0.023	NA	0.037	7.3e-06	NA	2.8e-03	NA	2.3e-04
9	METSIM	Adipose	0.0852	0.0230	4.9e-08	0.068	0.057	0.050	0.062	0.068	2.4e-10	6.6e-09	5.7e-08	1.4e-09	2.3e-10
10	NTR	Blood	0.1173	0.0209	0.0e+00	0.149	0.130	0.145	0.148	0.151	8.7e-46	1.4e-39	2.7e-44	2.7e-45	2.4e-46
11	ROSMAP	Brain Pre-frontal Cortex	0.1049	0.0251	8.2e-12	0.155	0.084	0.141	0.130	0.148	2.0e-19	5.4e-11	1.0e-17	2.0e-16	1.3e-18
12	YFS	Blood	0.4004	0.0324	0.0e+00	0.404	0.428	0.455	0.428	0.441	2.9e-144	3.0e-155	1.3e-168	1.3e-155	1.1e-161
13	TCGA	Colon Adenocarcinoma	0.1090	0.0800	5.6e-03	0.002	0.049	0.048	NA	0.003	2.5e-01	8.2e-04	9.1e-04	NA	2.0e-01
14	TCGA	Brain Lower Grade Glioma	0.0811	0.0365	3.6e-05	0.012	0.050	0.041	NA	0.035	1.4e-02	2.4e-06	1.7e-05	NA	6.4e-05
15	TCGA	Lung Adenocarcinoma	0.0159	0.0099	9.7e-03	0.014	0.007	0.006	NA	0.006	8.5e-03	4.6e-02	6.2e-02	NA	5.5e-02
16	TCGA	Pheochromocytoma and Paraganglioma	0.1550	0.0660	4.8e-03	0.078	0.017	0.038	NA	0.036	5.3e-04	6.8e-02	1.2e-02	NA	1.5e-02
17	TCGA	Prostate Adenocarcinoma	0.0308	0.0159	2.7e-04	0.029	0.032	0.015	NA	0.022	4.5e-04	2.4e-04	1.0e-02	NA	2.1e-03
18	TCGA	Thyroid Carcinoma	0.0350	0.0200	5.8e-03	0.010	0.019	0.004	NA	0.011	3.1e-02	4.9e-03	1.1e-01	NA	2.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Triglycerides	39.0	63.9	132.2	-9.1	-6.5	-7.1	5.0	-5.6	6.2	-8.7	-7.8	-8.8	-7.4	-6.0	-8.5	-11.2	-11.5	-10.2	-6.3	-8.5	-5.2
High cholesterol (Self-reported)	13.3	23.5	45.3	-6.0	-3.4	-4.9	1.2	-6.0	2.1	-4.6	-5.5	-5.9	-4.6	-2.8	-4.6	-6.3	-6.7	-5.4	-5.9	-3.9	-2.8
Cholesterol lowering medication	10.3	15.1	26.0	-5.1	-3.5	-3.9	2.5	-3.3	1.3	-4.3	-4.4	-4.6	-4.0	-3.2	-4.0	-4.7	-4.6	-4.9	-3.2	-3.9	-2.5
LDL Cholesterol	8.6	13.5	25.6	-4.1	-2.5	-3.6	2.2	-2.8	3.0	-3.6	-4.0	-4.3	-3.5	-2.4	-3.9	-5.1	-5.0	-4.5	-3.6	-3.6	-3.0
Medication: Cholesterol lowering	8.1	12.6	23.6	-4.3	-2.8	-3.9	1.4	-2.7	2.2	-3.0	-4.3	-4.6	-3.7	-2.5	-3.6	-4.4	-4.9	-4.0	-3.8	-3.2	-2.5
Cardiovascular Disease	8.0	26.3	44.9	-6.7	-4.7	-6.1	2.0	-2.6	2.3	-4.0	-6.4	-6.3	-5.8	-4.3	-5.4	-6.4	-6.0	-5.9	-4.1	-5.2	-4.6
HDL Cholesterol	7.0	11.6	33.7	-3.9	-3.1	-5.0	2.5	-3.2	1.7	-3.2	-4.5	-5.8	-4.1	-3.1	-5.0	-1.7	1.1	-1.5	-3.2	-2.0	-1.6
Medication: Atorvastatin	7.0	8.7	17.2	-3.6	-2.1	-2.9	2.4	-3.3	1.2	-2.8	-3.3	-3.6	-2.9	-1.9	-2.5	-3.7	-4.1	-3.5	-3.3	-2.4	-1.6
Serious illness, injury or assault of a close relative in last 2 years	6.9	8.0	13.8	-3.3	-3.7	-3.5	2.0	1.7	1.3	-0.9	-3.6	-3.0	-3.7	-3.6	-3.1	-1.7	-1.6	-2.9	0.2	-3.4	-3.6
Medication: Simvastatin	6.5	9.5	18.0	-4.0	-2.4	-3.4	0.8	-2.2	1.8	-2.3	-3.7	-3.6	-3.2	-2.1	-3.0	-4.1	-4.2	-3.5	-3.3	-2.9	-2.6
Medication for cholesterol, blood pressure or diabetes	6.5	10.8	20.1	4.0	3.0	3.6	-2.1	2.4	-2.4	3.5	3.8	4.5	3.7	2.8	3.3	3.6	3.5	3.7	2.9	3.1	1.9
Medication: Gliclazide	5.8	6.5	11.7	-2.9	-2.7	-3.4	2.4	1.8	2.3	-1.2	-3.1	-2.8	-3.0	-2.6	-2.9	-1.9	-1.9	-2.7	-0.3	-2.9	-3.2
Alzheimer’s Disease (including proxy)	5.7	8.3	13.6	-3.6	-3.3	-3.1	2.8	-0.3	1.6	-2.4	-3.2	-3.0	-3.4	-3.2	-3.2	-2.3	-2.2	-3.6	-0.3	-3.7	-3.2
Medication for cholesterol	5.5	8.3	15.5	3.9	3.2	3.4	-1.6	0.1	-2.3	2.2	3.4	3.1	3.4	3.0	3.0	3.3	2.6	3.5	1.0	3.4	2.8
Illnesses of mother	5.3	6.5	10.6	3.3	2.6	3.1	-2.1	0.9	-0.9	1.6	3.2	2.8	3.1	2.5	2.9	2.8	2.6	2.9	1.5	2.8	2.6
Blood Platelet Count	5.0	58.5	102.0	10.1	8.7	9.3	-6.2	-0.4	-6.3	5.8	9.7	9.8	9.4	8.3	8.0	6.2	4.6	8.2	2.2	8.5	7.9
Alzheimer’s Disease (in mother)	4.8	5.6	8.8	-2.9	-2.6	-2.5	1.8	-1.0	1.1	-2.0	-2.7	-2.7	-2.7	-2.4	-2.9	-2.2	-2.5	-3.0	-1.0	-2.8	-2.3
Alcohol intake versus 10 years previously	4.8	7.2	12.9	3.4	3.2	3.4	-1.5	-0.4	-2.0	2.1	3.5	3.2	3.3	2.9	3.6	2.4	1.4	2.7	0.9	2.9	2.7
Systolic Blood Pressure	4.7	23.4	39.6	-6.3	-4.3	-5.4	2.1	-2.9	4.1	-4.9	-5.8	-5.4	-5.4	-3.8	-5.4	-5.4	-5.4	-5.3	-4.5	-4.7	-4.2
High blood pressure (mother)	4.7	6.6	10.9	-3.3	-2.8	-3.3	2.0	-0.0	0.5	-2.2	-3.1	-2.5	-3.2	-2.8	-2.9	-2.5	-2.6	-2.9	-1.0	-3.0	-2.6
Birth weight of first child	4.7	8.6	16.1	3.6	3.1	4.0	-2.4	0.1	-1.9	1.6	4.0	3.8	3.8	3.0	3.4	2.2	1.7	2.9	1.3	3.0	3.5
Ever taken oral contraceptive pill	4.6	5.1	10.5	-2.7	-1.9	-2.2	2.8	1.1	1.5	-1.0	-2.4	-1.6	-2.4	-2.1	-2.0	-2.1	-3.0	-3.1	0.3	-2.8	-3.2
Medication: Blood pressure	4.3	7.6	12.7	-3.4	-3.0	-3.3	2.1	-0.7	2.2	-2.4	-3.3	-3.6	-3.4	-2.8	-2.9	-2.6	-2.5	-3.2	-1.3	-2.9	-2.1
Rheumatoid Arthritis	4.1	5.7	8.9	3.0	2.6	2.6	-2.9	0.7	-2.3	2.5	2.5	2.9	2.7	2.6	2.4	1.6	2.0	2.6	1.1	2.6	1.8
Medication: Metformin	4.1	5.7	10.8	-2.7	-3.1	-3.0	1.8	0.2	1.5	-1.8	-3.1	-3.2	-3.2	-3.1	-3.3	-1.2	-0.9	-2.5	-0.0	-2.4	-2.1
High blood pressure	3.7	10.4	18.1	-4.2	-3.3	-4.2	1.2	-0.9	2.0	-2.2	-4.2	-3.8	-4.0	-3.1	-3.7	-3.6	-2.9	-3.4	-2.2	-3.4	-3.1
Qualifications: None of the above	3.7	7.9	29.3	2.7	1.1	2.8	-0.3	0.9	1.2	0.7	3.2	2.3	2.5	1.2	3.5	4.6	5.4	2.8	3.5	2.3	3.3
Bipolar Disorder (2011)	3.6	3.5	7.6	-1.6	-1.2	-2.7	0.2	-0.9	0.4	0.1	-2.2	-1.9	-1.9	-1.1	-2.5	-2.6	-2.3	-1.0	-2.7	-1.4	-2.8
Vascular/heart problems diagnosed by doctor	3.4	9.3	16.8	4.1	2.8	3.8	-0.8	1.5	-1.6	2.1	3.9	3.6	3.6	2.6	3.4	3.6	3.3	3.3	2.7	3.1	2.8
Diabetes (self-reported)	3.3	5.1	9.3	-2.6	-2.6	-3.0	1.7	-0.0	1.9	-1.1	-2.9	-2.9	-2.9	-2.5	-3.1	-1.7	-1.4	-2.4	-0.6	-2.3	-2.3
Hypertension (Self-reported)	3.3	9.2	15.7	-4.0	-3.3	-3.9	1.3	0.2	2.1	-1.9	-3.9	-3.4	-3.8	-3.1	-3.4	-3.3	-2.6	-3.2	-1.5	-3.3	-3.2
Lung FVC	3.0	15.3	31.7	4.6	4.8	5.0	-2.9	-0.2	-3.7	3.7	4.9	5.6	5.0	4.7	5.0	2.5	0.9	3.6	1.0	3.9	2.9
Type 2 Diabetes (T2D) (2018)	2.9	5.4	9.4	-2.8	-3.1	-2.9	1.3	0.2	1.5	-1.8	-2.9	-2.9	-3.0	-3.0	-3.0	-1.3	-1.0	-2.6	0.2	-2.5	-2.1
Pain type(s) experienced in last month: Hip pain	2.9	3.6	6.7	2.0	1.2	1.8	-1.1	1.4	0.2	1.8	2.3	1.9	1.9	1.1	2.6	2.5	2.6	2.2	2.0	1.9	2.0
Hayfever/allergic rhinitis (self-reported)	2.8	3.7	6.9	-1.1	-2.6	-1.5	2.1	2.2	2.3	-2.3	-1.3	-1.1	-1.8	-2.6	-1.4	-1.3	0.4	-2.2	2.4	-2.6	-1.3
Diabetes diagnosed by doctor	2.7	4.4	7.7	-2.4	-2.3	-2.7	1.5	-0.4	2.1	-1.2	-2.7	-2.7	-2.7	-2.3	-2.8	-1.6	-1.5	-2.2	-0.7	-2.0	-2.0
Medication: Omeprazole (e.g. Zanprol)	2.7	3.3	7.8	-1.4	-2.8	-1.4	2.3	2.2	1.9	-2.1	-1.4	-2.2	-1.9	-2.7	-1.0	1.0	1.4	-1.2	2.2	-1.5	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.4	7.9	2.1	1.5	2.3	-0.5	-1.6	-0.8	0.4	2.2	1.4	2.0	1.4	2.8	2.0	2.4	1.8	1.1	2.0	2.7
Qualifications: nursing, teaching	2.6	4.1	7.5	-2.2	-1.9	-2.5	1.8	-0.1	-0.1	-0.8	-2.7	-2.2	-2.5	-2.0	-2.4	-1.9	-2.3	-2.2	-0.8	-2.1	-2.7
Guilty feelings	2.6	3.9	7.4	1.8	2.2	1.6	-2.5	-2.0	-2.5	0.5	1.6	1.0	1.9	2.0	2.0	1.8	1.6	2.5	-1.5	2.5	2.7
Medication: Bendroflumethiazide	2.6	4.0	6.9	-2.6	-2.1	-2.4	0.2	-1.2	1.3	-1.6	-2.6	-2.3	-2.4	-1.9	-2.5	-1.9	-1.7	-2.1	-1.5	-2.1	-1.7
Hypothyroidism (self reported)	2.5	5.7	26.3	-1.0	1.7	-1.2	-2.5	-2.4	-2.0	1.6	-1.4	0.2	-0.1	2.1	-1.1	-3.6	-5.1	-1.0	-4.7	0.1	-2.9
Time employed in main current job	2.5	2.9	7.5	-1.9	-2.5	-1.8	1.8	1.2	1.8	-1.9	-1.3	-1.6	-2.0	-2.7	-1.3	-0.3	0.3	-1.7	1.5	-2.1	-0.8
Mother’s age at death	2.5	3.1	8.5	-1.7	-0.8	-1.9	0.8	-0.8	1.0	0.1	-2.3	-1.6	-1.5	-0.6	-2.4	-2.9	-2.5	-1.6	-2.4	-1.5	-2.4
Blood Eosinophil Count	2.4	18.5	88.9	3.2	-1.5	2.6	3.0	9.1	2.0	0.9	3.2	3.3	1.4	-2.1	3.1	6.2	6.4	2.0	9.4	0.6	2.3
Medication: Blood pressure	2.4	4.5	8.2	-2.9	-2.0	-2.4	-0.1	-0.5	2.0	-2.0	-2.5	-2.1	-2.3	-1.9	-2.4	-2.7	-2.2	-2.4	-1.7	-2.3	-1.9
Illnesses of father: High blood pressure	2.4	2.9	7.7	-1.8	-2.0	-1.9	2.2	-0.4	2.8	-1.8	-1.8	-2.2	-2.0	-2.0	-1.4	-1.1	-0.1	-1.6	0.2	-1.7	-0.8
Coronary Artery Disease (CAD)	2.3	2.8	10.4	-1.2	0.1	-0.8	0.8	-2.9	-0.1	-1.2	-1.4	-1.4	-0.8	-0.1	-1.0	-2.9	-3.1	-1.4	-3.2	-1.0	-0.6
Diabetes (father)	2.3	2.8	4.6	-2.1	-1.9	-1.9	2.1	0.2	0.6	-1.2	-1.8	-1.7	-1.9	-1.9	-2.1	-1.4	-1.4	-2.0	0.1	-2.0	-1.6
Had major operations	2.3	2.7	6.1	1.9	1.6	1.9	-1.3	-1.8	-0.2	-0.1	1.7	0.9	1.6	1.6	2.0	1.7	1.2	2.1	-0.4	2.3	2.5
Waist Hip Ratio (WHR)	2.2	9.8	20.1	-3.4	-4.2	-3.8	2.6	2.1	4.5	-3.5	-2.9	-3.9	-3.7	-4.3	-3.4	-0.2	1.5	-2.5	1.5	-3.1	-1.4
Stomach or abdominal pain in last month	2.2	2.8	6.2	2.1	0.8	1.7	-0.4	0.7	-2.0	0.9	1.8	1.3	1.5	0.8	1.8	2.4	2.5	2.1	1.7	1.8	1.9
Migraine (self-reported)	2.2	2.7	7.9	1.6	2.0	1.3	-2.8	1.1	-2.4	1.6	1.3	1.8	1.6	2.0	1.6	1.4	0.3	1.9	-0.7	1.8	0.6
Ever smoked	2.2	3.9	8.4	2.3	1.7	2.3	-1.2	0.1	-1.3	0.3	2.1	1.6	2.0	1.6	2.4	2.9	2.4	2.5	0.5	2.5	2.7
Breast Cancer	2.1	5.0	21.3	-1.9	0.2	-1.7	-0.5	-4.4	-0.5	-1.7	-2.5	-2.7	-1.5	0.3	-2.0	-2.9	-2.5	-1.6	-4.6	-0.8	-1.1
Past tobacco smoking	2.1	3.8	7.7	-2.2	-1.9	-2.3	1.5	0.5	1.4	-0.5	-2.1	-1.7	-2.1	-1.8	-2.3	-2.4	-1.8	-2.5	0.1	-2.6	-2.8
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.5	7.7	1.9	1.7	2.2	-1.2	-2.2	-2.0	0.3	2.1	1.2	2.1	1.8	2.2	2.3	1.5	1.7	0.4	2.2	2.8
Qualifications: A levels/AS levels or equivalent	2.1	4.6	10.8	-2.2	-0.9	-2.3	1.1	-1.6	-0.4	-1.8	-2.9	-2.4	-2.1	-0.9	-2.5	-3.1	-3.3	-2.1	-2.9	-1.5	-1.9
High blood pressure (siblings)	2.1	3.0	5.3	-2.3	-2.0	-1.9	0.7	-0.9	0.6	-1.3	-1.8	-2.1	-2.0	-1.8	-2.0	-2.2	-1.3	-2.2	-0.6	-2.2	-1.7
Loneliness, isolation	2.1	3.0	6.6	2.1	1.3	1.9	-1.5	-0.2	-0.8	1.0	2.0	1.5	1.8	1.3	2.2	1.9	2.6	2.1	0.9	1.9	2.1
Osteoarthritis (self-reported)	2.1	2.7	6.4	1.9	1.1	1.9	-0.8	0.3	0.0	-0.1	2.0	1.5	1.8	1.1	1.8	2.5	2.4	1.5	1.6	1.7	2.4
Average weekly champagne plus white wine intake	2.1	2.9	8.0	-1.8	-1.0	-1.6	-0.3	-0.7	-1.3	-1.0	-2.1	-1.7	-1.6	-0.7	-2.1	-2.0	-2.8	-1.8	-2.3	-1.5	-2.3
Ovarian Cancer	2.0	2.7	14.3	-1.0	-2.3	-1.3	0.8	-0.5	1.0	-3.8	-1.4	-2.6	-1.7	-2.2	-1.6	0.5	1.7	-0.7	-0.0	-1.1	1.0
Type 2 Diabetes (T2D) (2012)	2.0	2.3	4.1	-1.7	-1.5	-1.6	1.0	-0.5	-0.5	-0.9	-1.9	-1.9	-1.7	-1.3	-1.6	-1.8	-1.7	-2.0	-0.1	-1.7	-2.0
Ulcerative Colitis	2.0	2.9	9.0	1.7	1.0	1.4	-1.5	0.8	-0.4	2.0	1.5	1.3	1.4	1.0	1.8	3.0	2.8	2.2	1.9	1.8	1.2
Happiness	2.0	2.4	4.0	1.6	1.8	1.9	-0.9	-2.0	-1.9	0.2	1.4	1.1	1.7	1.8	1.4	1.8	1.0	1.6	-0.5	1.9	1.9
Leg fat percentage (right)	2.0	7.2	26.0	2.0	-0.4	2.4	0.4	2.6	2.1	-0.7	2.8	1.7	1.5	-0.6	3.2	4.6	5.0	1.6	5.1	1.1	3.1
Medication: Ramipril	1.9	2.5	8.1	-2.0	-1.2	-1.4	0.9	-1.1	0.1	-0.7	-1.7	-1.5	-1.4	-1.0	-1.5	-2.3	-2.8	-2.0	-1.7	-1.6	-1.2
Alcohol drinker status: Previous	1.9	2.2	4.4	1.9	1.2	1.9	-1.8	-0.2	-0.7	0.2	1.8	1.4	1.6	1.1	1.4	1.5	2.1	1.7	1.1	1.5	1.9
Smoking Status	1.8	4.3	14.9	2.0	0.6	2.2	-0.3	1.4	0.7	-0.3	2.3	1.6	1.8	0.7	2.2	3.9	3.2	2.1	2.1	2.0	3.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	12.4	0.2	-1.5	-0.2	0.8	1.6	1.5	-1.8	-0.1	-1.0	-0.5	-1.3	-0.1	2.5	3.5	0.6	1.8	0.2	1.7
Leg fat percentage (left)	1.8	6.5	24.0	1.7	-0.4	2.2	0.4	2.6	2.4	-0.9	2.6	1.6	1.3	-0.7	3.0	4.3	4.6	1.4	4.9	1.0	3.0
Pain experienced in last month	1.8	3.0	6.1	-2.2	-1.1	-1.8	0.9	-1.5	0.5	-2.3	-2.0	-1.8	-1.7	-0.9	-2.2	-1.9	-2.5	-1.9	-2.1	-1.4	-1.1
Medication for hormone replacement therapy	1.7	1.9	4.8	-1.4	-1.8	-1.2	2.2	1.6	1.8	-0.8	-1.2	-1.3	-1.5	-1.9	-1.3	-0.2	0.8	-1.1	1.2	-1.4	-0.7
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	17.4	-1.0	1.2	-1.1	-1.3	-1.7	-1.0	0.7	-1.2	-0.0	-0.2	1.5	-0.8	-3.0	-4.2	-1.2	-3.5	-0.2	-2.3
Forced vital capacity (FVC), Best measure	1.7	6.2	14.9	2.6	3.5	2.7	-2.7	0.7	-2.5	3.5	2.6	3.9	2.9	3.2	2.9	1.1	-0.7	1.8	0.7	2.1	0.0
Illnesses of father: Heart disease	1.7	2.4	12.8	0.8	1.6	1.4	-2.2	-3.6	-0.5	-0.8	0.8	0.5	1.3	1.8	0.7	-0.9	-1.4	0.1	-2.5	1.0	1.8
Back pain experienced in last month	1.7	2.4	7.0	1.5	1.7	1.5	-0.7	0.8	-0.4	2.6	1.8	2.1	1.8	1.5	2.1	1.6	1.5	1.6	1.1	1.5	0.6
Myopia	1.7	2.5	5.7	-1.8	-2.1	-1.5	1.7	0.4	2.4	-1.9	-1.3	-2.0	-1.9	-2.2	-1.3	-0.3	0.4	-1.4	1.1	-1.7	-0.8
Major Depression (MDD)	1.6	1.9	8.2	0.5	-1.1	0.2	1.6	1.6	1.2	-1.4	-0.3	-1.2	-0.8	-1.6	0.3	2.1	2.9	0.8	1.9	0.1	1.3
Neuroticism	1.6	3.9	16.1	2.0	0.9	1.7	-1.0	-0.7	-0.9	-0.3	1.8	0.8	1.6	1.0	1.8	3.3	4.0	2.7	0.8	2.2	3.2
Hayfever, allergic rhinitis or eczema	1.6	3.4	8.2	-1.2	-2.3	-0.8	2.7	1.8	1.9	-1.8	-0.7	-0.7	-1.4	-2.5	-1.1	-1.5	-0.3	-2.5	2.9	-2.7	-1.2
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	11.4	-0.7	0.7	-1.0	-1.5	-2.9	-0.6	0.4	-1.3	-1.1	-0.6	0.6	-1.2	-1.2	-1.6	-0.3	-3.4	0.2	-0.5
Forced vital capacity (FVC)	1.6	6.1	13.0	2.6	3.5	2.7	-2.9	0.0	-3.6	3.2	2.3	3.6	2.8	3.3	2.4	0.5	-1.5	1.7	-0.3	2.1	0.2
Neuroticism score	1.6	3.3	8.5	2.1	1.4	1.8	-1.8	-1.3	-1.6	0.3	1.7	1.1	1.7	1.4	1.8	2.5	2.6	2.3	0.0	2.1	2.9
Medication: Amlodipine	1.6	2.2	4.8	-1.7	-1.3	-2.1	-0.0	-0.0	0.9	-0.1	-1.8	-1.8	-1.8	-1.2	-2.0	-1.1	-2.2	-1.5	-1.1	-1.3	-1.9
Body fat percentage	1.6	6.3	27.6	2.0	-0.1	2.0	0.4	3.6	1.9	0.8	2.7	2.2	1.5	-0.4	3.1	3.7	4.0	1.4	5.2	0.8	1.8
Age at first live birth	1.6	2.9	5.2	-2.0	-1.7	-1.8	1.2	-0.7	1.4	-2.2	-1.7	-1.6	-1.8	-1.8	-1.9	-1.7	-1.9	-2.3	-0.2	-2.0	-1.4
Pulse wave peak to peak time	1.6	1.8	3.5	-1.8	-1.6	-1.2	1.7	-1.0	0.6	-1.5	-1.4	-1.6	-1.6	-1.6	-1.9	-0.6	-0.7	-1.5	-0.8	-1.5	-0.5
Chronotype (morning person)	1.5	3.4	6.5	1.6	2.3	2.2	-2.5	1.2	-1.7	1.7	1.9	2.3	2.0	2.0	2.5	2.1	0.4	1.5	1.0	1.8	0.7
Number of treatments/medications taken	1.5	2.6	5.3	-2.2	-2.3	-2.0	0.7	0.2	1.0	-1.6	-2.0	-2.1	-2.1	-2.1	-1.4	-1.1	-0.9	-1.8	-0.4	-1.9	-1.1
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	3.6	1.6	0.4	1.3	0.6	0.8	-1.1	1.0	1.4	1.2	1.2	0.6	1.7	1.8	1.9	1.6	1.1	1.4	1.8
Pulse wave Arterial Stiffness index	1.5	1.8	3.3	1.7	1.6	1.2	-1.7	1.0	-0.6	1.6	1.3	1.7	1.6	1.6	1.8	0.5	0.5	1.4	0.8	1.4	0.3
Leg fat mass (right)	1.5	5.9	28.1	1.9	-0.4	2.2	0.3	3.4	1.4	0.3	2.5	1.8	1.3	-0.6	3.0	3.8	3.9	1.3	5.3	0.9	2.0
Age at last live birth	1.5	2.1	4.6	-1.6	-1.6	-1.6	0.8	-0.5	1.2	-2.2	-1.3	-1.5	-1.6	-1.5	-1.5	-1.5	-1.6	-1.9	-0.2	-1.8	-1.2
Arm fat percentage (left)	1.5	6.1	29.6	1.9	-0.2	1.9	0.4	4.2	1.6	1.3	2.5	2.5	1.4	-0.5	3.2	3.3	3.5	1.2	5.4	0.5	1.1
Ulcerative Colitis (UC)	1.4	2.6	8.7	1.2	0.4	1.0	-0.5	2.7	0.1	2.7	1.4	1.9	0.9	0.4	1.8	2.1	1.8	1.3	3.0	0.8	-0.5
Arm fat percentage (right)	1.4	5.7	27.6	1.8	-0.3	1.8	0.3	4.1	1.4	0.9	2.4	2.2	1.3	-0.6	2.9	3.3	3.6	1.1	5.2	0.5	1.3
Knee pain experienced in last month	1.4	2.2	8.6	1.3	-0.0	0.8	-0.5	2.3	0.7	1.8	1.2	1.1	0.8	-0.2	1.2	2.6	2.2	1.2	2.9	0.6	0.3
Smoking status: Previous	1.4	2.2	3.7	1.7	1.6	1.8	-1.5	-0.3	-0.7	0.9	1.6	1.6	1.7	1.6	1.7	1.6	1.0	1.8	-0.3	1.9	1.7
Commuting to job workplace: Walk	1.4	1.5	4.4	-1.2	-1.1	-1.2	0.6	-0.8	0.1	-1.3	-1.2	-1.2	-1.1	-1.0	-1.6	-2.1	-1.5	-1.2	-1.3	-1.2	-0.7
Irritability	1.4	2.3	5.3	1.7	1.1	1.9	-0.2	-0.0	0.1	-0.1	2.0	1.6	1.6	0.9	1.9	2.2	2.3	1.5	1.2	1.6	2.1
Leg fat mass (left)	1.4	5.5	26.4	1.7	-0.4	2.0	0.3	3.4	1.5	0.2	2.3	1.7	1.2	-0.7	2.8	3.7	3.7	1.2	5.1	0.8	2.0
HbA1C	1.3	1.4	3.1	-1.0	-1.2	-1.4	0.4	0.8	1.8	-1.3	-1.2	-1.1	-1.3	-1.4	-1.3	-0.8	-0.9	-1.5	0.4	-1.5	-1.2
Lung FEV1/FVC ratio	1.3	6.5	15.9	-2.3	-3.7	-2.4	4.0	1.4	3.0	-3.5	-2.3	-3.2	-2.8	-3.7	-2.1	-0.6	0.7	-1.9	1.4	-2.3	-0.2
Systolic blood pressure, automated reading	1.3	3.6	5.9	-2.4	-1.7	-2.0	1.1	-0.9	2.4	-1.7	-2.2	-1.7	-2.0	-1.4	-2.1	-2.2	-2.4	-2.0	-1.7	-1.8	-1.9
Pack years adult smoking proportion	1.3	2.0	8.4	-0.5	-1.8	-0.5	1.9	1.2	1.5	-0.8	-0.4	-0.9	-1.0	-2.0	0.2	1.4	2.4	-0.4	2.9	-1.0	-0.4
Trunk fat percentage	1.3	5.3	24.3	1.9	0.0	1.9	0.4	3.6	1.5	1.2	2.5	2.4	1.5	-0.2	3.1	3.1	3.3	1.2	4.9	0.7	1.3
Average weekly fortified wine intake	1.3	1.6	3.3	-1.5	-1.8	-1.4	1.3	0.7	-0.6	-1.4	-1.6	-1.7	-1.6	-1.7	-1.3	-0.2	0.0	-1.0	-0.1	-1.2	-0.9
Waist circumference	1.3	4.6	23.6	-0.4	-2.6	-0.3	2.0	3.7	2.7	-1.0	0.2	-0.6	-1.0	-2.8	0.5	2.3	3.1	-0.7	4.9	-1.2	0.4
Illnesses of siblings	1.3	1.8	3.5	1.6	1.5	1.3	-0.5	1.0	-0.4	1.5	1.2	1.9	1.5	1.3	1.5	1.5	1.3	1.6	1.0	1.5	0.7
Alcohol intake frequency.	1.3	2.9	5.0	2.1	1.2	1.9	-1.1	1.3	-1.0	2.0	2.2	2.1	1.7	1.1	2.0	2.2	1.5	1.7	2.1	1.4	1.3
Family relationship satisfaction	1.3	1.6	5.4	1.5	1.5	1.5	-0.6	-1.1	-2.3	0.6	1.4	1.1	1.5	1.5	1.1	0.7	0.2	1.3	-0.6	1.5	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	4.8	2.0	1.9	2.1	-1.5	0.2	-1.1	1.1	2.2	2.2	2.1	1.8	2.0	1.4	0.7	1.5	1.0	1.6	1.4
Allergy or Eczema	1.2	3.2	12.4	-0.5	-2.5	-0.5	2.4	2.0	2.1	-2.3	-0.3	-0.6	-1.2	-2.6	-0.7	-0.1	1.5	-1.7	3.5	-2.1	-0.2
Diabetes (mother)	1.2	1.5	4.1	-1.3	-2.0	-1.2	1.3	0.5	1.0	-1.3	-1.2	-1.5	-1.5	-1.9	-1.1	-0.2	0.1	-1.4	0.8	-1.3	-0.4
Current tobacco smoking	1.2	2.0	9.2	0.9	-0.4	1.0	1.1	0.8	0.5	-1.2	1.1	0.2	0.6	-0.4	1.1	2.6	3.0	1.1	2.2	0.7	2.2
Serious illness, injury or assault to yourself	1.2	1.4	4.6	0.9	1.4	1.3	-1.7	-2.1	0.1	0.3	1.3	1.1	1.4	1.5	1.2	0.5	0.5	0.7	-0.2	1.3	1.2
Alcohol usually taken with meals	1.2	2.0	5.8	-1.3	-0.2	-1.5	-0.1	0.1	-0.5	-0.0	-1.7	-1.3	-1.2	-0.2	-1.5	-2.3	-2.3	-1.4	-1.8	-1.2	-2.4
Medication: Lansoprazole	1.2	1.4	6.9	0.2	-0.9	0.2	0.5	-0.1	0.2	-2.6	-0.1	-1.2	-0.4	-1.1	0.3	1.8	2.5	0.3	0.8	0.2	1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	5.6	0.9	1.4	1.0	-1.0	-1.3	-2.4	-0.4	0.9	0.2	1.0	1.4	0.2	0.7	1.0	1.4	-0.8	1.6	1.7
Number of self-reported non-cancer illnesses	1.2	2.1	4.5	-1.9	-1.9	-2.1	0.6	0.6	1.1	-1.0	-1.8	-1.9	-1.9	-1.8	-1.2	-0.8	-0.7	-1.5	-0.4	-1.6	-1.2
Age started oral contraceptive pill	1.2	1.5	5.6	-0.3	0.6	-0.5	-0.9	-0.8	-0.8	1.8	-0.6	0.4	0.0	0.8	-0.9	-2.3	-2.4	-0.5	-2.0	-0.4	-1.7
Bipolar Disorder (2018)	1.1	1.8	4.2	-1.3	-1.1	-2.1	0.0	0.5	0.6	-0.2	-1.8	-1.7	-1.7	-1.1	-1.5	-1.6	-1.2	-1.2	-1.0	-1.3	-2.0
Depression (Nagel 2018)	1.1	1.7	3.3	1.7	1.1	1.3	-0.9	-1.1	-1.0	1.0	1.1	0.8	1.3	1.2	1.7	1.3	1.6	1.8	-0.1	1.7	1.6
Blood White Count	1.1	8.1	31.7	3.0	0.3	2.4	-0.3	3.1	-0.8	-0.2	2.6	1.3	1.8	-0.0	2.4	4.9	5.6	3.1	3.9	2.2	4.1
Frequency of depressed mood in last 2 weeks	1.1	1.6	4.8	1.6	0.6	1.0	-0.7	-1.1	-1.5	0.8	0.8	0.3	0.8	0.6	1.4	1.6	2.2	1.8	0.4	1.5	1.7
Trunk fat mass	1.1	4.7	24.8	1.7	-0.2	1.6	0.4	3.9	1.3	1.2	2.1	2.1	1.2	-0.4	2.8	2.8	2.8	0.8	5.0	0.4	0.7
Worrier / anxious feelings	1.1	2.0	4.7	0.8	1.4	0.9	-2.1	-2.2	-1.4	0.5	0.8	0.1	1.0	1.2	0.9	1.8	1.4	1.5	-1.6	1.7	2.1
Health satisfaction	1.1	1.5	4.3	-1.5	-0.6	-1.4	1.1	-1.2	-0.1	0.2	-1.5	-1.0	-1.2	-0.7	-0.9	-1.2	-2.1	-1.5	-0.8	-0.9	-1.8
Emphysema/chronic bronchitis	1.1	1.2	3.6	1.1	1.1	0.9	-0.5	-1.3	-1.9	-0.2	0.8	0.5	1.0	1.1	1.0	1.2	0.7	1.3	-1.1	1.4	1.3
Whole body fat mass	1.1	4.4	24.8	1.5	-0.5	1.5	0.6	3.8	1.6	0.9	2.0	1.8	1.0	-0.7	2.5	2.8	2.8	0.7	5.0	0.2	0.9
Medication: Lisinopril	1.1	1.4	4.1	-0.8	-1.8	-0.6	1.2	0.3	1.9	-2.0	-0.7	-1.0	-1.2	-1.8	-0.9	0.1	0.6	-1.2	1.5	-1.1	0.4
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.4	1.0	1.4	1.4	-1.2	-1.2	-1.4	0.0	0.9	0.9	1.2	1.5	1.5	0.5	-0.4	0.8	-1.5	1.3	1.6
Pack years of smoking	1.1	1.7	6.2	-0.6	-1.7	-0.6	1.9	0.9	1.5	-0.7	-0.6	-0.9	-1.1	-1.9	0.1	1.4	2.1	-0.4	2.5	-0.9	-0.5
Irritable Bowel Disease (IBD)	1.0	2.3	8.6	1.3	0.3	1.2	-0.9	2.2	0.4	1.8	1.4	1.7	0.9	0.4	1.7	2.5	2.0	1.1	2.9	0.9	0.0
Heel T-Score	1.0	8.2	15.1	-3.1	-3.8	-3.2	3.0	2.7	3.0	-2.0	-2.8	-2.7	-3.5	-3.9	-3.3	-1.8	-1.0	-2.7	0.6	-3.6	-2.5
Relative age of first facial hair	1.0	2.0	3.6	1.5	1.7	1.9	-1.2	-1.3	-1.3	0.3	1.8	1.6	1.7	1.5	1.4	1.2	0.8	1.3	0.1	1.5	1.8
Medication: Atenolol	1.0	1.2	4.5	-1.1	-0.3	-0.8	-0.6	-1.0	-0.5	-1.4	-1.1	-1.2	-0.8	-0.1	-1.2	-1.5	-1.9	-1.1	-2.1	-0.6	-0.2
Body mass index (BMI)	1.0	4.5	23.6	1.5	-0.7	1.6	0.5	3.4	1.0	0.0	1.9	1.3	0.8	-1.1	2.4	3.1	3.5	0.9	4.9	0.4	1.7
Arm fat mass (right)	1.0	4.1	23.7	1.4	-0.6	1.5	0.4	3.9	1.0	0.9	1.8	1.7	0.9	-0.8	2.4	2.6	2.8	0.7	4.9	0.2	0.8
Number of children fathered	1.0	1.1	7.2	-0.7	0.0	-0.2	-0.3	-2.1	1.4	-1.0	-0.3	-0.1	-0.2	0.3	-0.5	-1.3	-2.7	-1.1	-1.3	-0.4	-0.1
Medication: Allopurinol	1.0	1.3	4.8	1.3	1.0	1.3	-0.9	-1.0	-2.2	0.6	1.2	0.6	1.2	1.1	1.0	0.5	0.3	1.2	-0.7	1.2	1.6
Chest pain or discomfort	1.0	1.5	4.4	1.4	0.6	1.2	0.6	0.6	0.0	0.7	1.2	1.0	1.0	0.5	1.4	2.0	2.1	1.4	1.1	1.2	1.6
Neuroticism (Nagel 2018)	0.9	2.0	8.0	1.2	0.5	1.0	-1.2	-0.8	-0.1	0.1	1.2	0.5	1.0	0.5	1.4	2.8	2.7	1.8	0.5	1.5	2.3
Body Mass Index (BMI) (2010)	0.9	1.3	3.0	-1.1	-1.4	-0.4	1.6	1.1	1.5	-1.0	-0.7	-0.6	-1.1	-1.5	-0.6	-0.3	-0.8	-1.7	1.1	-1.6	-0.8
Primary Biliary Cirrhosis	0.9	1.2	2.6	1.1	1.4	1.6	-0.6	-0.5	-1.2	0.9	1.3	1.5	1.5	1.5	1.3	0.6	-0.1	0.8	0.0	1.3	0.9
Chronic bronchitis/emphysema (father)	0.9	1.1	2.9	1.0	0.9	1.1	-0.1	0.7	-1.4	1.7	1.1	1.4	1.1	1.0	1.4	1.0	0.8	1.0	0.5	1.0	0.4
Hair/balding pattern: Pattern 2	0.9	1.2	2.8	-1.2	-1.1	-1.0	1.4	1.7	1.6	-0.8	-0.5	-0.4	-1.0	-1.4	-0.5	0.1	-0.8	-1.1	1.1	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	9.8	1.8	2.3	1.9	-1.7	0.7	-3.1	1.9	1.6	2.5	1.9	2.0	1.6	0.2	-1.2	1.0	0.2	1.2	0.1
Mouth/teeth dental problems: Dentures	0.9	1.5	6.7	0.9	-0.2	1.2	0.3	1.1	0.6	-0.3	1.3	0.7	0.9	0.1	1.4	2.6	1.9	1.1	1.7	0.9	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	7.6	1.8	2.2	1.9	-1.6	1.3	-1.9	2.0	1.9	2.8	2.0	1.9	2.3	0.7	-0.3	1.1	1.3	1.2	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	4.2	1.1	0.9	0.7	-1.2	0.0	-0.3	1.5	0.9	0.4	0.9	0.8	0.8	2.0	1.7	2.0	-0.4	1.8	1.2
Neck or shoulder pain in last month	0.9	1.3	2.4	-1.0	-1.3	-1.5	0.9	1.4	1.1	-0.2	-1.3	-1.2	-1.4	-1.4	-0.7	-0.3	0.0	-1.1	1.3	-1.2	-1.6
Medication: Omeprazole	0.9	1.1	3.2	-0.6	-1.6	-0.4	1.2	1.2	1.0	-1.1	-0.4	-1.2	-0.9	-1.5	-0.3	0.9	1.3	-0.3	1.8	-0.5	0.4
Smoking status: Current	0.9	1.5	6.3	0.8	-0.0	1.0	0.6	0.2	0.4	-1.1	1.0	0.2	0.7	0.0	1.0	2.3	2.5	1.1	1.5	0.9	2.2
Arm fat mass (left)	0.9	3.8	22.8	1.3	-0.6	1.3	0.4	3.7	1.1	0.8	1.7	1.6	0.8	-0.9	2.4	2.3	2.5	0.5	4.8	0.1	0.7
Commuting to job workplace: Cycle	0.9	1.1	4.9	0.4	1.1	0.5	-1.2	-2.2	-0.8	-1.8	0.2	-0.2	0.5	0.9	0.3	0.2	-0.2	0.8	-1.8	1.2	1.3
Basal cell carcinoma (self-reported)	0.9	1.1	4.8	-1.1	-0.4	-0.6	0.2	-0.1	1.3	-0.4	-0.9	-0.3	-0.7	-0.3	-1.0	-1.1	-2.2	-1.4	-0.5	-1.2	-1.7
Depressed Affect (Nagel 2018)	0.8	1.7	6.7	1.1	0.5	1.3	-1.4	-0.2	0.1	0.2	1.4	0.7	1.1	0.5	1.5	2.6	2.0	1.5	1.0	1.3	2.1
Worry (Nagel 2018)	0.8	1.8	7.3	1.2	0.7	0.8	-0.9	-1.4	0.0	0.2	1.1	0.4	1.0	0.7	0.8	2.3	2.7	1.8	-0.0	1.5	2.1
Fasting Glucose	0.8	0.9	3.2	-1.0	-0.9	-0.7	0.2	0.7	1.3	-0.1	-0.6	-0.4	-0.7	-0.8	-0.1	-1.0	-1.8	-1.5	0.5	-1.4	-1.4
BMI	0.8	4.9	29.4	1.1	-1.6	1.1	0.9	4.3	0.4	-0.1	1.4	0.7	0.2	-1.9	2.0	3.4	3.3	0.7	5.4	0.0	1.2
Fed-up feelings	0.8	1.4	4.4	1.2	0.7	1.5	-0.6	-1.4	-0.8	-1.1	1.4	0.9	1.1	0.6	1.5	1.5	1.0	0.8	0.9	1.0	2.1
Heart attack	0.8	1.0	2.4	0.7	1.1	1.1	-1.0	-1.1	-1.1	-0.5	0.7	0.5	1.0	1.1	1.2	0.5	-0.3	0.6	-1.5	1.1	1.5
Allergy	0.8	1.9	7.2	0.5	1.7	0.5	-2.6	-1.6	-1.6	0.4	0.2	0.1	0.8	1.8	0.6	0.6	-0.3	1.5	-2.7	1.8	1.0
Asthma	0.8	1.6	7.6	-0.6	-1.6	-0.6	2.2	0.7	2.8	0.1	-0.2	-0.6	-0.8	-1.6	-0.6	0.9	1.6	-0.5	2.1	-0.9	-0.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	5.2	-0.1	0.5	-0.4	-1.8	-0.2	-2.3	0.3	-0.9	-0.5	-0.2	0.6	-0.6	-1.5	-2.1	-0.0	-2.2	0.2	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	3.5	-1.0	-0.6	-0.7	0.8	-1.9	-0.2	-0.5	-1.0	-1.2	-1.0	-0.8	-0.6	-0.5	-0.9	-0.9	-1.4	-0.7	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	5.2	-0.0	-0.8	-0.6	0.8	2.3	-0.2	1.3	-0.0	0.2	-0.4	-1.0	0.0	0.7	1.0	0.0	2.2	-0.6	-0.9
Intelligence (Savage-Jansen 2018)	0.7	2.0	11.4	-0.4	1.0	0.2	-0.4	-3.4	-2.1	-1.4	-0.4	-0.7	0.3	1.2	-0.4	-1.6	-1.7	-0.2	-2.8	0.8	1.1
Blood Red Count	0.7	6.5	13.8	3.7	2.4	3.1	-1.7	-0.8	-2.0	1.7	3.2	2.2	3.0	2.4	3.0	1.9	2.5	3.1	0.9	2.8	3.4
Average weekly spirits intake	0.7	0.8	1.9	-1.0	-1.0	-1.1	0.1	0.9	-0.8	-0.0	-1.3	-0.9	-1.1	-1.0	-0.8	-0.5	-0.9	-1.0	-0.1	-0.9	-1.4
Age when periods started (menarche)	0.7	1.8	4.1	1.1	1.8	1.5	-1.3	-2.0	0.8	-0.5	1.5	1.4	1.6	1.8	1.2	1.2	0.3	0.8	-0.4	1.4	1.7
Qualifications: CSEs or equivalent	0.7	0.9	5.9	0.7	-1.0	0.1	0.3	0.7	-0.1	-0.7	0.0	-0.4	-0.3	-1.1	0.2	1.4	2.4	0.7	1.5	-0.1	1.0
Medication: Levothyroxine sodium	0.7	1.1	6.4	-0.4	0.9	-0.3	-1.3	-1.0	-0.5	0.2	-0.5	0.3	0.1	1.2	0.0	-1.5	-2.5	-0.5	-2.0	0.2	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	4.0	0.8	0.7	1.1	-0.4	-2.0	-0.2	-0.1	1.0	0.6	0.9	0.7	1.6	1.5	1.0	0.8	0.0	1.1	1.8
Financial difficulties in last 2 years	0.7	1.0	3.8	0.9	0.8	1.3	0.4	-0.9	-0.6	-0.6	1.2	0.8	1.1	0.7	1.1	1.1	0.7	0.8	0.0	1.0	1.9
Father’s age at death	0.7	0.9	2.8	1.0	1.7	0.6	-0.6	-0.3	-1.2	1.6	0.5	0.5	1.0	1.6	0.5	-0.2	-0.5	0.9	-0.9	1.1	-0.2
Falls in the last year	0.7	0.9	3.4	1.0	0.5	0.9	-0.8	0.2	0.4	0.7	0.9	0.8	0.9	0.5	1.2	1.8	1.3	1.0	0.9	1.1	1.2
Pulse rate	0.7	1.2	2.0	1.4	0.7	0.8	-1.1	1.1	0.4	1.2	1.0	1.4	1.0	0.8	1.3	1.3	1.2	1.4	0.9	1.1	0.7
Length of working week for main job	0.7	0.8	3.5	0.5	0.1	0.8	0.6	0.7	-1.2	-0.5	0.8	0.1	0.4	-0.2	0.8	1.1	1.9	0.7	1.6	0.5	1.0
Hair/balding pattern: Pattern 4	0.7	1.7	11.4	-0.4	0.5	-0.3	-1.2	-3.4	-0.3	-0.4	-0.7	-1.1	-0.1	0.8	-0.7	-2.2	-1.1	-0.1	-2.9	0.3	0.5
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.3	1.1	0.4	0.8	-0.2	1.5	-0.8	1.8	0.9	1.0	0.8	0.5	1.1	0.0	1.3	1.0	1.1	0.6	0.3
Wheeze or whistling in the chest in last year	0.7	1.3	6.5	0.7	-0.6	0.5	1.1	0.1	1.3	-0.8	0.9	0.1	0.2	-0.7	1.0	1.9	2.6	0.7	1.4	0.4	1.7
Mean time to correctly identify matches	0.7	1.4	3.6	1.1	0.6	0.9	-0.6	1.0	0.8	1.4	1.4	1.1	1.2	0.9	1.2	1.7	1.9	1.3	1.1	1.0	0.7
Number of full sisters	0.7	0.8	3.2	-1.0	-0.9	-0.8	1.4	-0.5	1.8	-0.9	-0.7	-0.8	-0.8	-0.7	-0.5	-0.6	-0.7	-1.2	0.1	-0.8	-0.6
Leg pain on walking	0.7	0.9	1.8	0.9	1.1	1.2	-0.7	-0.6	0.6	0.9	1.3	1.1	1.3	1.2	1.3	-0.2	0.2	0.7	-0.4	1.0	1.3
Mood swings	0.7	1.2	5.0	0.9	0.1	1.1	-0.8	1.0	-0.5	-0.3	1.0	0.8	0.7	-0.0	1.8	2.2	1.6	0.7	1.7	0.5	1.2
Asthma (self-reported)	0.7	1.3	5.8	-0.6	-1.5	-0.6	2.2	0.5	2.4	-0.2	-0.3	-0.7	-0.8	-1.5	-0.6	0.7	1.4	-0.5	1.8	-0.8	-0.1
Number of operations (self-reported)	0.7	1.0	2.9	1.3	0.7	1.3	-0.5	-0.2	-0.6	0.5	1.1	0.8	1.0	0.6	1.7	1.2	0.7	1.3	0.2	1.3	1.4
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.1	1.0	0.9	0.6	-0.7	-1.4	-0.7	0.4	0.5	0.1	0.7	0.9	0.3	0.6	0.6	1.4	-0.8	1.4	1.3
Supplements: Zinc	0.6	0.7	2.2	-0.4	0.1	-0.8	-0.0	0.3	-0.3	1.4	-0.8	-0.1	-0.4	0.0	-0.9	-1.5	-1.3	-0.4	-0.8	-0.4	-1.5
Hand grip strength (right)	0.6	1.6	5.0	1.2	1.6	1.7	-0.9	-1.2	-2.2	-0.1	1.4	1.5	1.4	1.5	1.3	-0.3	-1.5	0.1	0.1	0.8	0.7
Had menopause	0.6	0.8	3.4	0.6	0.9	0.4	-1.3	-0.0	-0.5	1.9	0.6	1.0	0.8	1.2	-0.1	-1.4	-0.4	0.5	-1.1	0.5	-0.3
Weight	0.6	2.9	21.2	1.0	-0.7	1.0	0.7	3.8	0.7	1.1	1.2	1.2	0.4	-1.0	1.8	1.8	1.6	0.0	4.6	-0.3	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	3.5	0.9	0.6	0.8	-0.4	-0.1	-0.9	0.2	0.8	0.7	0.7	0.6	0.9	1.3	1.9	0.9	0.8	1.0	1.0
Prospective memory result	0.6	0.7	4.3	0.0	-0.2	-0.4	-0.0	2.1	-0.3	1.7	0.0	0.9	-0.1	-0.2	0.6	-0.5	-0.3	-0.4	1.0	-0.7	-1.7
Breastfed as a baby	0.6	0.7	2.3	0.6	1.0	0.4	-1.5	0.1	-1.4	1.2	0.2	0.6	0.6	1.1	-0.0	-1.2	-0.7	0.3	-0.3	0.4	-1.0
Tense / ‘highly strung’	0.6	0.9	3.2	1.1	0.5	0.8	-0.6	-0.0	0.3	0.1	1.0	0.8	0.9	0.5	0.9	1.4	1.8	1.3	0.7	1.1	1.5
Blood clot in the leg (DVT)	0.6	0.7	2.0	0.9	0.8	0.7	-0.3	1.1	-0.8	1.3	0.7	0.8	0.7	0.7	1.2	1.4	0.4	0.8	0.8	0.9	0.0
Qualifications: College or University degree	0.6	2.0	6.9	-0.9	0.2	-0.6	0.1	-2.5	-1.9	-0.6	-1.2	-0.6	-0.5	0.3	-1.5	-2.2	-2.4	-1.0	-2.6	-0.5	-1.0
Supplements: Vitamin C	0.6	0.7	1.7	-0.7	-0.6	-1.0	0.9	-0.0	-0.1	0.8	-0.9	-0.5	-0.8	-0.5	-0.9	-1.2	-1.3	-0.8	-0.7	-0.7	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	4.5	-1.2	-0.4	-1.1	0.5	-0.9	-0.6	-0.7	-1.2	-0.9	-1.0	-0.5	-1.3	-2.1	-1.9	-1.2	-0.9	-1.2	-1.4
Average weekly red wine intake	0.6	0.9	4.9	-0.2	0.6	-0.0	-0.5	-1.8	-0.8	-1.0	-0.5	-0.7	0.0	0.7	-0.0	-1.0	-1.9	-0.6	-2.2	0.2	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.8	0.8	0.4	0.7	-0.5	-0.6	-2.0	0.8	0.7	0.5	0.7	0.7	0.7	1.0	1.4	1.5	-0.4	1.2	1.1
Eye problems/disorders: Glaucoma	0.6	0.7	2.6	0.6	0.2	0.8	0.0	1.0	0.6	0.6	0.6	0.4	0.6	0.3	0.9	1.6	1.5	0.9	0.5	0.9	0.9
Average weekly beer plus cider intake	0.6	0.8	3.1	0.5	0.2	0.7	-0.3	0.2	1.8	0.0	1.0	0.6	0.6	0.1	1.0	0.9	1.5	0.8	1.6	0.7	1.2
Age at First Birth	0.5	0.7	4.0	-0.4	-0.1	-0.6	-0.2	-1.9	0.3	-0.6	-0.6	-0.3	-0.1	0.4	-1.0	-0.8	-1.3	-0.3	-2.0	0.1	-0.2
Mean Putamen Volume	0.5	0.6	2.4	-0.6	-0.7	-0.6	1.2	1.6	1.1	0.5	-0.5	-0.3	-0.7	-0.8	-0.4	-0.8	0.1	-0.2	0.7	-0.6	-0.8
Lupus	0.5	0.8	6.0	-0.2	0.8	0.1	-1.7	-2.4	-0.5	-0.3	-0.1	-0.3	0.2	0.9	0.3	0.3	-0.6	0.3	-1.2	0.8	0.6
Hair Pigment	0.5	14.3	21.1	-4.5	-4.4	-4.5	4.1	1.0	3.5	-3.0	-4.5	-4.2	-4.6	-4.5	-4.0	-2.9	-2.4	-4.2	0.1	-4.3	-3.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.1	-0.5	0.3	-0.7	-0.6	-0.7	-0.9	1.4	-0.8	-0.1	-0.3	0.4	-0.3	-0.7	-1.4	-0.2	-1.2	0.0	-1.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.9	-0.6	-0.6	-0.4	1.0	-0.3	1.7	-0.8	-0.7	-0.6	-0.7	-0.7	-0.7	-0.2	0.5	-0.5	0.6	-0.5	-0.3
Medication: Co-codamol	0.5	0.6	1.7	0.6	1.1	0.8	-1.2	-0.0	-1.2	0.9	0.6	0.7	0.9	1.0	1.3	0.5	0.1	0.2	0.1	0.7	-0.0
Sitting height	0.5	3.4	15.1	-1.4	-0.4	-1.8	0.5	-0.1	-0.6	1.1	-1.9	-1.1	-1.4	-0.4	-1.8	-3.0	-3.9	-1.9	-0.8	-1.7	-3.5
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	2.4	-0.5	-1.1	-0.7	1.6	-0.4	0.1	-1.0	-0.8	-1.2	-1.0	-1.0	-0.8	-0.3	-0.6	-0.6	-0.7	-0.5	0.1
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.6	0.3	-0.4	0.3	-0.2	1.4	-0.7	0.5	0.5	0.3	0.2	-0.3	0.6	1.2	1.5	0.4	1.6	0.1	0.2
Worry too long after embarrassment	0.5	0.8	2.5	0.5	0.8	0.4	-1.3	-1.6	-1.5	1.2	-0.0	-0.0	0.5	1.0	0.4	0.6	0.2	0.9	-1.5	1.0	0.5
Shortness of breath walking on level ground	0.5	0.6	1.4	-1.0	-1.2	-0.6	0.6	0.4	-0.4	-1.0	-0.9	-1.0	-1.0	-1.2	-0.5	-0.2	-0.2	-0.7	-0.2	-0.8	-0.1
Medication for pain relief, constipation, heartburn	0.5	0.9	4.3	-0.1	1.1	0.5	-0.7	-2.0	-0.6	0.3	0.2	0.3	0.5	1.1	-0.1	-1.0	-2.1	-0.1	-1.6	0.3	-0.4
Medication: Ibuprofen	0.5	0.6	3.8	0.7	0.5	0.6	-0.4	-0.6	-0.2	-0.0	0.7	0.6	0.6	0.5	1.0	0.9	1.9	0.8	0.5	0.8	0.9
Heart disease (mother)	0.5	0.7	2.6	-1.2	-0.7	-0.5	0.6	0.0	-0.0	0.3	-0.8	-0.8	-0.9	-0.8	-0.1	-0.5	-1.6	-1.2	0.2	-0.9	-1.2
Comparative height size at age 10	0.5	2.6	14.9	1.7	1.3	0.9	-0.3	3.1	-1.8	3.9	0.9	2.0	1.2	1.3	0.8	0.4	-0.2	1.4	1.1	1.0	-1.2
Suffer from ‘nerves’	0.5	0.8	5.2	1.0	-0.1	0.3	-0.1	-0.2	-0.8	0.1	0.4	-0.1	0.3	-0.2	-0.0	1.3	2.3	1.5	0.8	0.8	1.4
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.9	-0.6	-0.8	-0.4	0.6	0.1	0.9	-1.4	-0.7	-1.2	-0.7	-0.9	-0.1	1.1	1.0	-0.4	0.5	-0.1	0.7
Friendships satisfaction	0.5	0.6	1.7	0.8	0.6	1.3	-0.2	-0.8	-1.0	-0.3	0.9	0.6	0.8	0.6	0.8	1.0	0.4	0.3	0.4	0.7	1.1
Breast cancer (self-reported)	0.5	0.6	2.4	0.3	0.8	0.3	-0.7	0.4	0.1	1.5	0.3	1.1	0.6	0.9	0.6	-1.4	-0.9	0.1	-0.6	-0.0	-0.6
Financial situation satisfaction	0.5	0.6	1.9	0.4	0.6	0.9	0.1	-1.2	-0.4	-1.0	0.9	0.3	0.8	0.6	1.0	1.0	0.3	0.1	0.0	0.7	1.4
Diastolic blood pressure, automated reading	0.5	1.7	4.2	-1.1	-1.4	-1.6	1.0	-0.0	0.6	-0.4	-1.6	-1.5	-1.6	-1.3	-1.4	-2.0	-1.6	-1.0	-0.7	-1.2	-1.6
Bipolar Disorder or Schizophrenia	0.4	1.1	5.0	-0.7	-1.3	-1.3	0.3	2.2	0.7	0.0	-0.9	-0.6	-1.2	-1.4	-0.5	-0.4	0.2	-0.5	1.0	-1.0	-1.5
Schizophrenia (2018)	0.4	0.9	5.9	0.1	-0.8	0.0	0.4	2.4	0.4	0.2	0.3	0.6	-0.2	-0.9	0.5	0.8	1.2	0.4	2.1	-0.3	-0.3
Schizophrenia vs Biploar Disorder	0.4	0.6	3.1	0.0	-0.2	0.7	1.8	-0.2	0.4	-0.7	0.5	-0.1	0.2	-0.3	0.3	1.2	1.1	0.2	1.0	0.1	1.3
Crohns Disease (2017)	0.4	0.8	3.0	0.8	0.2	1.2	-1.0	0.1	0.7	0.1	1.0	1.0	0.7	0.4	0.9	1.7	1.0	0.3	1.7	0.7	0.7
Reaction Time	0.4	0.8	2.5	0.9	0.5	0.7	-0.6	0.8	0.6	0.8	0.9	0.8	0.9	0.7	1.1	1.6	1.4	1.1	0.8	0.9	0.7
Respiratory disease	0.4	1.0	3.1	1.2	0.2	1.0	0.2	0.1	0.5	0.8	1.0	0.6	0.8	0.2	1.0	1.6	1.8	1.1	1.5	0.8	1.2
Hand grip strength (left)	0.4	1.1	2.6	1.1	0.9	1.6	-1.1	-1.6	-1.4	-0.4	1.3	1.0	1.1	0.9	1.3	0.4	-0.4	0.2	0.9	0.8	1.1
Sensitivity / hurt feelings	0.4	0.6	2.5	-0.5	-0.6	-0.5	0.5	-0.6	0.4	-1.6	-0.7	-1.2	-0.7	-0.7	-0.2	1.3	1.2	0.1	-0.4	0.2	1.0
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.1	-0.5	-0.1	-0.7	0.0	1.5	-0.1	1.4	-0.3	0.2	-0.1	0.1	-0.5	-0.9	-0.3	0.1	-0.6	-0.3	-1.2
Severe depression (siblings)	0.4	0.4	2.9	-0.4	0.2	-0.1	0.4	-0.3	-0.5	1.0	-0.2	0.1	0.0	0.3	-0.1	-1.1	-1.7	-0.7	-0.5	-0.2	-0.9
Townsend deprivation index at recruitment	0.4	0.6	1.4	0.7	0.2	0.8	0.4	-1.1	0.9	-0.3	0.8	0.7	0.6	0.2	1.1	0.8	1.2	0.4	0.5	0.5	1.2
Leg predicted mass (left)	0.4	1.9	12.2	0.4	-0.6	0.4	0.3	3.5	-0.6	1.9	0.3	0.9	-0.0	-0.8	0.9	0.5	-0.2	-0.4	3.3	-0.6	-1.5
Number of incorrect matches in round	0.4	0.7	4.4	-0.2	-0.5	-0.7	1.3	2.1	1.1	1.8	-0.1	0.1	-0.3	-0.5	-0.3	-0.3	-0.2	-0.1	0.5	-0.6	-0.9
Hearing difficulty/problems with background noise	0.4	0.6	2.8	-0.6	-0.0	-0.2	0.5	-1.7	1.6	-1.1	-0.5	-0.9	-0.2	0.0	-0.4	1.1	0.3	-0.0	-0.3	0.4	0.6
Mouth/teeth dental problems	0.4	0.6	1.7	-0.4	0.3	-0.5	-0.0	-1.2	1.1	-0.8	-0.6	-0.3	-0.4	-0.0	-1.0	-1.1	-1.3	-0.8	-0.9	-0.5	-0.5
Fluid intelligence score	0.4	0.9	3.9	-0.8	-0.4	-0.2	-0.1	-2.0	0.6	-2.0	-0.8	-1.2	-0.5	-0.3	-0.8	-0.5	-1.0	-0.8	-1.0	-0.3	0.6
Hip circumference	0.4	1.8	12.6	0.7	-0.7	0.8	0.8	2.7	0.7	0.9	0.9	1.0	0.3	-0.9	1.5	1.5	1.2	-0.0	3.5	-0.2	-0.1
Hair/balding pattern: Pattern 3	0.4	0.5	2.2	-0.9	-0.5	-0.8	-0.0	-1.1	-0.4	-0.2	-1.1	-1.1	-0.8	-0.3	-0.8	0.2	-0.2	-0.2	-1.5	-0.3	-0.4
Number of live births	0.4	0.5	2.1	0.1	-0.0	0.1	-1.3	-0.7	0.6	-0.4	0.4	-0.4	0.2	0.2	0.3	1.2	1.5	0.5	-0.2	0.7	1.2
Noisy workplace	0.4	0.5	2.1	0.7	0.7	0.6	-1.5	0.8	-0.1	1.0	0.7	1.0	0.7	0.7	0.3	0.4	0.3	0.5	0.3	0.4	-0.2
Lung cancer (father)	0.4	0.5	1.8	-0.2	-0.7	-0.1	0.7	1.1	1.3	-1.0	0.2	-0.1	-0.3	-0.8	-0.4	0.1	0.6	-0.3	1.4	-0.5	0.2
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.5	-0.3	-0.7	-0.5	0.5	0.6	1.2	-0.8	-0.6	-0.9	-0.6	-0.6	-0.8	-1.0	-1.0	-0.8	-0.2	-0.6	-0.4
Glaucoma (self-reported)	0.4	0.5	2.6	0.3	-0.4	0.4	0.6	0.8	0.9	-0.3	0.4	0.1	0.2	-0.3	0.6	1.3	1.6	0.4	0.7	0.4	1.0
Birth weight	0.4	0.9	3.1	0.4	1.0	0.7	-0.6	-1.8	-0.9	0.8	0.6	0.7	0.9	1.2	0.3	-1.4	-1.6	-0.5	-0.7	0.2	-0.5
Exposure to tobacco smoke outside home	0.4	0.5	2.6	-0.2	-1.0	-0.4	0.5	0.7	0.5	-0.5	-0.5	-0.7	-0.7	-1.1	-0.1	0.8	1.6	0.1	1.1	-0.1	0.2
Number of full brothers	0.4	0.5	3.0	-0.1	0.3	-0.1	-0.7	-1.7	-1.3	-0.3	-0.4	-0.8	-0.1	0.4	-0.6	-0.4	-0.5	0.2	-1.5	0.4	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.0	0.6	0.6	0.6	0.2	-0.4	-1.4	1.2	0.5	0.5	0.7	0.7	0.9	0.4	0.7	0.9	-0.6	0.7	0.8
Angina (self-reported)	0.4	0.5	1.1	0.1	0.7	0.7	-1.1	-0.8	1.1	-0.6	0.7	0.7	0.7	0.8	1.0	0.0	-0.5	-0.2	-0.6	0.2	0.5
Pulse rate, automated reading	0.4	1.4	5.8	-0.5	-1.5	-0.5	1.6	1.7	2.3	-0.6	0.1	0.2	-0.6	-1.4	0.2	0.6	0.6	-0.8	2.4	-1.1	-0.5
Overall health rating	0.4	0.9	3.8	-0.9	-0.5	-0.7	-0.1	-1.9	1.8	-1.6	-0.5	-1.4	-0.6	-0.6	-0.4	0.7	1.0	-0.6	-0.4	-0.2	0.8
Ever had bowel cancer screening	0.4	0.5	3.3	-0.1	-0.9	-0.7	0.7	0.2	1.8	-0.5	-0.6	-1.0	-0.6	-0.7	-0.1	-0.2	1.2	0.2	-0.2	-0.1	0.1
Eye problems/disorders: Cataract	0.4	0.5	2.8	-1.0	-0.4	-0.7	0.2	0.0	0.2	0.4	-0.8	-0.1	-0.6	-0.4	-0.3	-0.1	-1.7	-1.1	-0.7	-0.7	-1.0
Miserableness	0.4	0.7	2.4	0.6	0.3	0.9	-0.9	-0.1	0.3	0.1	1.0	0.5	0.7	0.3	1.3	1.6	1.2	0.5	1.1	0.6	1.1
Alcohol drinker status: Never	0.4	0.5	1.2	0.0	-1.1	-0.6	1.1	1.0	-0.2	0.9	-0.3	-0.2	-0.7	-0.9	0.0	-0.5	-0.3	-0.3	0.8	-0.6	-0.9
Fractured/broken bones in last 5 years	0.4	0.5	1.5	-0.7	-0.6	-0.6	0.4	-0.7	1.2	-1.0	-0.5	-0.5	-0.5	-0.5	-0.8	-1.1	-0.4	-0.8	-0.6	-0.6	0.2
Ever depressed for a whole week	0.4	0.4	2.6	0.4	-0.3	0.0	-0.0	-0.1	-1.1	-0.8	-0.3	-0.7	-0.2	-0.2	-0.1	1.6	0.8	0.6	-0.6	0.6	1.0
Unable to work because of sickness or disability	0.4	0.6	2.5	0.6	0.7	0.2	-1.2	-0.4	-1.6	1.1	0.0	0.2	0.4	0.5	0.7	0.3	1.0	1.0	-0.5	0.9	0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.6	0.6	0.8	0.3	-0.3	0.7	-0.6	1.3	0.4	0.5	0.5	0.7	0.9	1.2	0.1	0.6	0.3	0.8	-0.2
Heart disease (siblings)	0.4	0.5	2.7	-0.6	0.1	-0.2	-0.7	-1.7	0.5	-0.6	-0.0	-1.0	-0.0	0.4	-0.1	-0.5	-0.9	-0.4	-1.3	-0.0	0.5
Alzheimer’s Disease (in father)	0.3	0.4	1.3	-0.6	-0.5	-0.4	1.2	0.4	0.1	0.4	-0.5	-0.3	-0.5	-0.6	-0.4	-0.6	-0.0	-0.7	0.5	-1.0	-1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	4.8	-0.6	-0.2	-0.1	0.5	-2.2	0.3	-2.0	-0.6	-1.0	-0.4	-0.2	-0.5	-0.6	-0.5	-0.6	-1.2	-0.0	1.0
Prostate Cancer	0.3	0.4	1.3	0.7	-0.1	0.1	-0.7	1.0	-1.0	0.4	0.4	0.3	0.2	-0.1	0.5	1.1	0.8	0.6	1.1	0.3	0.1
Schizophrenia (2014)	0.3	0.7	5.8	0.3	-0.7	-0.2	0.7	2.4	-0.2	1.0	0.2	0.3	-0.2	-0.6	0.5	0.5	0.9	0.4	1.4	-0.2	-0.5
Height	0.3	5.6	26.8	-1.1	-0.2	-1.7	1.2	3.2	0.8	2.9	-1.3	0.6	-1.0	-0.4	-1.4	-3.9	-4.3	-2.3	0.6	-2.3	-5.2
Hearing difficulty/problems: Yes	0.3	0.5	3.2	0.1	0.7	0.1	-0.9	-1.8	0.1	-0.4	-0.3	-0.9	0.2	0.7	-0.3	0.3	0.3	0.5	-1.0	0.8	0.5
Ever had hysterectomy (womb removed)	0.3	0.3	1.8	0.3	-0.2	0.2	0.2	1.4	0.2	1.2	0.5	0.5	0.3	0.1	0.5	0.0	0.2	0.1	0.7	-0.0	-0.5
Angina	0.3	0.4	1.0	0.0	0.7	0.6	-0.9	-0.7	1.0	-0.5	0.6	0.7	0.6	0.7	0.9	-0.2	-0.6	-0.2	-0.6	0.2	0.5
Leg fat-free mass (left)	0.3	1.8	11.7	0.5	-0.5	0.4	0.3	3.4	-0.6	1.9	0.3	1.0	0.0	-0.7	1.0	0.5	-0.2	-0.4	3.3	-0.5	-1.4
Maternal smoking around birth	0.3	0.5	2.9	-0.0	-0.7	0.1	0.5	0.3	0.7	-0.6	0.2	-0.4	-0.2	-0.8	0.2	0.9	1.7	0.3	1.1	-0.1	0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.4	0.3	0.4	0.4	-0.4	-0.8	-1.2	0.5	0.4	0.3	0.4	0.5	0.3	-0.7	-0.8	0.0	-0.6	0.3	0.3
Supplements: Glucosamine	0.3	0.4	1.9	0.3	-0.6	0.3	-0.6	1.2	1.4	-0.1	0.6	0.5	0.2	-0.5	0.1	0.4	0.6	-0.2	1.3	-0.4	0.4
Nervous feelings	0.3	0.6	4.7	-0.2	0.1	-0.4	-0.7	-2.2	-0.1	-0.0	-0.2	-0.7	-0.1	0.1	-0.5	0.6	1.0	0.7	-1.3	0.7	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.9	-0.4	-0.8	-0.4	1.4	0.6	1.7	-1.0	-0.3	-0.2	-0.5	-0.8	-0.3	-0.7	-1.0	-0.8	0.2	-0.6	-0.0
Pain all over the body in last month	0.3	0.3	2.4	0.4	0.5	0.4	-0.3	-0.6	-1.5	0.3	0.3	0.1	0.4	0.7	0.0	-0.5	-0.3	0.3	-0.9	0.5	0.4
Standing height	0.3	3.3	17.6	-0.9	0.1	-1.2	0.3	0.9	-0.7	2.4	-1.3	0.1	-0.8	0.2	-1.2	-2.8	-4.2	-1.7	-0.4	-1.4	-3.9
Loud music exposure frequency	0.3	0.3	1.5	0.3	0.1	0.6	-0.9	-1.2	-0.7	0.3	0.2	0.1	0.4	0.5	0.5	-0.4	-0.6	0.1	-0.7	0.7	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.0	0.9	0.7	0.7	-0.3	-0.0	-0.3	-0.3	0.7	0.3	0.7	0.5	0.7	0.1	0.6	0.5	0.5	0.6	1.0
Leg fat-free mass (right)	0.3	1.7	11.6	0.2	-0.7	0.2	0.2	3.4	-0.6	1.8	0.1	0.8	-0.2	-0.9	0.6	0.1	-0.6	-0.7	3.1	-0.8	-1.7
Long-standing illness, disability or infirmity	0.3	0.5	2.8	-0.8	-0.4	-0.7	-0.7	-1.7	-0.1	-0.5	-0.7	-1.1	-0.5	-0.3	-0.6	-0.4	-0.3	-0.2	-1.4	0.1	0.4
Osteoporosis (self-reported)	0.3	0.4	1.4	-0.5	-0.0	-0.4	0.2	0.9	-0.3	-0.2	-0.4	-0.1	-0.3	-0.0	-0.7	-0.9	-1.2	-0.8	-0.8	-0.6	-0.8
Leg predicted mass (right)	0.3	1.7	11.3	0.1	-0.7	0.2	0.2	3.4	-0.5	1.7	0.1	0.8	-0.2	-0.9	0.7	0.1	-0.7	-0.7	3.0	-0.8	-1.7
Risk taking	0.3	0.5	5.4	-0.1	0.4	0.0	-0.5	0.1	-2.3	0.3	-0.2	-0.0	0.2	0.6	0.4	-0.8	-0.6	0.2	-1.0	0.5	-0.1
Supplements: Calcium	0.3	0.3	2.5	0.2	0.3	0.1	0.1	0.0	0.2	0.3	0.1	0.4	0.2	0.3	-0.3	-1.6	-1.4	-0.4	-0.8	-0.1	-0.3
Crohns Disease (2012)	0.2	0.3	2.1	0.3	0.1	0.7	-1.0	-1.5	0.5	-0.3	0.4	0.4	0.3	0.3	0.2	0.1	-0.1	-0.2	0.3	0.3	0.6
Neuroticism (2016)	0.2	0.3	2.4	0.2	-0.6	-0.2	-0.0	0.2	-0.3	0.6	-0.2	-0.3	-0.3	-0.6	0.1	1.0	1.6	0.4	0.6	0.1	0.2
Impedance of leg (right)	0.2	0.8	5.4	0.0	0.5	0.2	0.1	-2.3	0.8	-1.3	0.3	-0.3	0.3	0.6	-0.1	0.4	0.8	0.4	-1.3	0.6	1.3
Taking other prescription medications	0.2	0.3	1.8	0.4	0.4	0.3	-0.7	-0.0	-0.2	0.0	0.2	0.1	0.3	0.3	0.6	1.4	0.1	0.4	-0.4	0.7	0.9
Multivitamins +/- minerals	0.2	0.2	2.1	0.1	0.0	0.2	-0.0	-1.5	0.2	-0.6	0.1	-0.3	0.1	0.2	-0.3	-0.2	0.1	0.3	-0.7	0.3	0.8
Impedance of leg (left)	0.2	0.8	5.1	-0.3	0.3	-0.1	0.1	-2.3	1.2	-1.6	-0.0	-0.6	-0.0	0.3	-0.5	0.0	0.4	0.1	-1.5	0.3	1.1
Had other major operations	0.2	0.3	1.4	0.0	-0.1	0.4	0.0	0.2	0.1	1.2	0.4	0.5	0.3	-0.1	0.8	0.2	0.5	-0.1	1.2	-0.0	-0.3
Trunk fat-free mass	0.2	0.9	3.3	-0.3	-0.8	-0.4	0.3	1.6	-0.8	0.9	-0.7	-0.3	-0.7	-0.9	-0.4	-0.8	-1.6	-1.1	1.3	-1.0	-1.8
Depression (self-reported)	0.2	0.2	0.5	0.0	-0.2	-0.1	-0.1	-0.3	-0.7	0.6	-0.3	-0.5	-0.1	-0.0	-0.5	0.6	0.5	0.7	-0.6	0.6	0.4
Impedance of arm (left)	0.2	0.7	4.7	0.2	1.1	-0.1	-0.4	0.5	-0.0	2.2	0.4	1.5	0.6	1.1	0.5	-0.6	-0.6	0.3	-0.4	0.1	-1.3
Trunk predicted mass	0.2	1.0	3.6	-0.3	-0.8	-0.4	0.3	1.6	-0.8	1.0	-0.7	-0.3	-0.8	-0.9	-0.5	-0.9	-1.6	-1.1	1.2	-1.0	-1.9
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.5	-0.5	-0.3	0.8	-0.0	0.4	-0.5	-0.5	-0.7	-0.5	-0.6	-0.6	0.3	0.3	-0.4	0.2	-0.2	-0.0
Peak expiratory flow (PEF)	0.2	0.5	1.4	0.8	0.3	1.2	-0.0	0.4	-0.5	-1.1	1.0	0.5	0.7	0.0	0.9	0.5	0.4	0.3	1.2	0.2	1.1
Pulse wave reflection index	0.2	0.2	2.8	0.1	-0.0	-0.2	-0.0	1.7	0.5	-0.4	-0.0	-0.1	0.0	-0.2	-0.2	-0.5	0.2	-0.2	0.7	-0.3	-0.1
Headache pain in last month	0.2	0.3	1.6	0.8	-0.4	0.1	0.5	1.0	0.3	0.5	0.3	0.3	-0.1	-0.5	0.2	0.3	0.9	0.3	1.3	-0.0	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	0.1	0.4	0.3	-0.0	-0.1	-1.1	0.7	-0.1	0.2	0.3	0.6	0.2	-0.4	-0.4	0.2	-0.4	0.2	-0.4
Eye problems/disorders: None of the above	0.2	0.2	1.1	0.3	0.2	0.2	-0.4	-0.8	0.3	-1.0	0.2	-0.2	0.1	0.2	-0.3	-1.0	0.3	0.3	-0.4	0.0	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.6	-0.4	0.1	-0.2	0.2	-1.2	0.1	0.2	-0.3	-0.1	-0.1	0.3	0.0	-0.9	-0.2	-0.1	-0.8	0.0	-0.5
Medication: Seretide 50 evohaler	0.2	0.2	1.1	-0.4	-0.3	-0.5	0.6	0.3	1.1	-0.1	-0.1	-0.1	-0.1	-0.0	-0.1	0.3	-0.1	-0.5	-0.0	-0.5	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	2.8	0.4	-0.1	0.2	-0.7	1.7	0.4	-0.4	0.3	0.2	0.1	-0.2	0.1	0.3	0.1	0.2	0.8	0.1	0.2
Medication: Aspirin	0.2	0.2	0.9	-0.3	-0.2	-0.4	-0.8	-0.0	0.3	-0.8	-0.6	-0.7	-0.3	-0.2	0.1	-0.6	0.1	-0.2	-0.9	-0.1	0.5
Illnesses of siblings: Diabetes	0.2	0.2	0.4	-0.6	-0.5	-0.2	0.5	0.5	0.3	-0.4	-0.4	-0.5	-0.5	-0.6	-0.5	0.4	0.2	-0.6	0.3	-0.4	-0.3
Whole body fat-free mass	0.2	1.0	5.7	0.0	-0.6	0.0	0.2	2.4	-0.8	1.3	-0.2	0.2	-0.4	-0.8	0.2	-0.2	-0.9	-0.7	2.1	-0.7	-1.6
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	-0.1	0.6	0.5	-0.9	-0.8	-1.1	0.3	0.2	0.3	0.3	0.7	0.4	-0.2	-0.7	-0.3	-0.6	0.2	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.2	0.8	-0.3	-0.1	-0.9	-0.7	0.5	0.2	0.1	-0.5	-0.5	-0.4	-0.1	-0.8	0.3	0.3	0.2	-0.3	0.1	-0.6
Whole body water mass	0.2	1.0	5.5	0.0	-0.6	0.0	0.2	2.4	-0.7	1.3	-0.2	0.2	-0.4	-0.8	0.2	-0.2	-0.8	-0.7	2.2	-0.7	-1.6
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.7	-0.2	-0.2	-0.3	0.2	1.3	-0.3	0.7	0.1	0.2	0.0	-0.2	-0.2	-0.9	-0.5	-0.2	0.1	-0.6	-0.7
Medication: Paracetamol	0.2	0.4	1.5	0.7	0.0	0.0	0.1	1.2	0.6	0.3	0.6	0.7	0.4	0.1	0.5	0.5	1.2	0.6	0.7	0.2	0.3
Basal metabolic rate	0.2	1.3	8.6	0.3	-0.7	0.3	0.3	2.8	-0.4	1.3	0.1	0.5	-0.2	-0.9	0.6	0.3	-0.3	-0.6	2.9	-0.7	-1.3
Vitamin and mineral supplements	0.1	0.2	1.6	0.0	0.5	0.2	-0.6	0.0	-1.2	-0.4	0.1	0.4	0.2	0.3	0.4	0.3	0.0	0.1	-0.2	0.2	0.1
Relative age voice broke	0.1	0.1	0.6	0.1	0.2	0.2	0.3	-0.8	0.1	-0.4	0.2	0.3	0.1	0.0	-0.5	-0.1	-0.7	-0.3	-0.1	-0.2	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.3	0.2	0.1	0.1	0.5	0.7	1.0	0.6	0.4	0.6	0.3	0.0	0.2	-0.7	-1.1	-0.0	0.2	-0.0	-0.1
Impedance of arm (right)	0.1	0.4	2.5	0.1	0.7	-0.3	-0.3	0.7	-0.3	1.6	0.0	0.9	0.3	0.7	0.1	-0.6	-0.5	0.2	-0.4	-0.0	-1.2
Medication: Paracetamol	0.1	0.2	1.5	0.4	-0.3	-0.5	-0.2	1.2	0.3	0.7	0.0	0.3	-0.1	-0.2	0.1	-0.2	0.5	0.2	0.4	-0.2	-0.4
Gout (self-reported)	0.1	0.2	0.7	0.0	-0.4	-0.1	0.7	-0.5	-0.8	-0.3	0.1	-0.6	-0.1	-0.3	-0.1	-0.1	-0.1	0.0	-0.6	-0.1	0.7
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.3	-0.5	-0.5	-0.6	0.4	0.1	0.5	-0.1	-0.5	-0.1	-0.4	-0.4	-0.5	-0.0	-0.5	-0.6	-0.2	-0.5	-0.5
Arm fat-free mass (right)	0.1	0.5	4.0	0.4	-0.4	0.5	-0.0	1.6	-0.5	0.7	0.3	0.3	0.0	-0.6	0.6	0.6	-0.0	-0.2	2.0	-0.2	-0.4
Comparative body size at age 10	0.1	0.2	1.7	0.1	-0.1	0.4	1.3	-0.1	0.2	-0.5	0.2	0.0	0.1	-0.2	-0.3	0.5	0.4	0.0	0.8	-0.0	0.3
Arm predicted mass (right)	0.1	0.6	4.5	0.3	-0.5	0.4	0.1	1.8	-0.2	0.8	0.2	0.3	-0.1	-0.7	0.5	0.3	-0.3	-0.3	2.1	-0.3	-0.6
Mineral and other dietary supplements	0.1	0.2	0.6	-0.5	-0.1	-0.3	0.3	-0.6	0.5	-0.8	-0.7	-0.7	-0.5	-0.2	-0.3	0.6	0.3	-0.2	0.0	0.0	-0.0
Medication: Aspirin	0.1	0.2	1.0	-0.2	0.1	-0.2	-1.0	0.1	-0.2	-0.5	-0.4	-0.4	-0.1	0.1	0.1	-0.3	0.1	-0.1	-0.9	0.1	0.4
Wears glasses or contact lenses	0.1	0.1	0.7	-0.0	-0.2	-0.2	0.0	0.0	0.8	0.3	0.2	0.2	0.1	-0.1	-0.0	0.6	0.7	0.2	0.4	-0.0	-0.2
Hearing aid user	0.1	0.1	0.8	0.1	0.2	0.1	0.2	-0.9	0.6	-0.4	-0.0	-0.2	0.1	-0.0	0.2	0.2	0.5	-0.1	0.6	-0.0	0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.6	0.3	0.6	0.3	-0.8	0.1	-0.0	0.4	0.2	0.3	0.4	0.6	0.5	0.0	-0.4	0.1	-0.1	0.3	-0.3
Commuting to job workplace: Public transport	0.1	0.1	0.3	0.4	0.2	0.3	-0.1	0.5	0.6	0.4	0.3	0.4	0.3	0.2	0.6	0.2	-0.0	0.2	0.4	0.0	-0.2
Arm fat-free mass (left)	0.1	0.5	3.8	0.2	-0.7	0.3	0.1	1.6	-0.4	0.4	0.1	-0.1	-0.2	-0.8	0.4	0.3	-0.2	-0.4	1.9	-0.3	-0.5
Impedance of whole body	0.1	0.3	1.4	-0.2	0.7	-0.3	-0.2	-0.9	0.6	0.5	0.1	0.5	0.3	0.8	-0.0	-0.6	-0.5	0.0	-1.2	0.1	-0.4
Arm predicted mass (left)	0.1	0.5	3.7	0.4	-0.5	0.5	0.1	1.6	-0.7	0.5	0.2	0.0	-0.1	-0.7	0.5	0.5	0.2	-0.1	1.9	-0.1	-0.2
Tanning	0.0	0.6	2.0	-0.4	-0.1	0.2	0.4	1.1	-0.8	0.9	0.3	0.9	0.1	0.1	0.5	-0.2	-0.8	-0.8	1.4	-0.7	-1.4

Hub : Genes

SIDT2

Models

Trait associations