TWAS hub - MED21

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue	0.11100	0.0450	8.3e-03	0.069	NA	0.036	NA	0.044	1.9e-04	NA	6.2e-03	NA	2.5e-03
2	GTEx	Breast Mammary Tissue (Male)	0.00273	0.0647	4.9e-01	-0.013	NA	-0.012	NA	0.023	9.4e-01	NA	7.8e-01	NA	9.8e-02
3	GTEx	Breast Mammary Tissue (Female)	0.12734	0.0786	8.8e-02	0.120	NA	0.043	NA	0.080	2.0e-04	NA	2.0e-02	NA	2.2e-03
4	GTEx	Cells Transformed fibroblasts	0.37000	0.0570	7.4e-15	0.172	NA	0.204	NA	0.196	6.9e-13	NA	3.1e-15	NA	1.2e-14
5	GTEx	Colon Sigmoid	0.29700	0.0940	9.9e-04	0.005	NA	0.057	NA	0.020	2.1e-01	NA	4.5e-03	NA	6.4e-02
6	GTEx	Esophagus Mucosa	0.29500	0.0530	3.2e-14	0.296	NA	0.272	NA	0.273	4.5e-20	NA	2.3e-18	NA	2.1e-18
7	GTEx	Esophagus Muscularis	0.10900	0.0450	7.6e-03	-0.002	NA	-0.003	NA	-0.002	4.2e-01	NA	6.1e-01	NA	4.3e-01
8	GTEx	Pancreas	0.14100	0.0570	6.6e-03	0.001	NA	0.004	NA	-0.004	2.8e-01	NA	2.1e-01	NA	4.9e-01
9	GTEx	Skin Not Sun Exposed Suprapubic	0.20200	0.0650	4.4e-04	0.005	NA	0.021	NA	0.013	1.6e-01	NA	2.3e-02	NA	6.1e-02
10	GTEx	Skin Sun Exposed Lower leg	0.15200	0.0400	2.9e-06	0.129	NA	0.108	NA	0.116	7.5e-11	NA	3.3e-09	NA	7.7e-10
11	GTEx	Testis	0.30700	0.0710	1.7e-05	0.088	NA	0.110	NA	0.099	9.7e-05	NA	1.4e-05	NA	3.8e-05
12	METSIM	Adipose	0.07500	0.0214	9.6e-07	0.016	0.021	0.009	0.021	0.012	1.6e-03	3.0e-04	1.6e-02	3.7e-04	5.4e-03
13	ROSMAP	Brain Pre-frontal Cortex	0.07660	0.0254	3.8e-05	-0.002	0.036	0.014	0.035	0.006	7.1e-01	1.6e-05	4.9e-03	2.4e-05	4.7e-02
14	YFS	Blood	0.03510	0.0109	8.1e-07	0.019	0.022	0.024	0.022	0.025	4.2e-07	9.0e-08	1.7e-08	8.2e-08	7.1e-09
15	TCGA	Breast Invasive Carcinoma	0.02980	0.0117	3.1e-05	0.014	0.023	0.023	NA	0.018	6.4e-04	1.2e-05	1.2e-05	NA	1.2e-04
16	TCGA	Cervical Squamous Cell Carcinoma	0.14200	0.0610	1.5e-04	0.045	0.068	0.047	NA	0.067	2.7e-03	3.1e-04	2.3e-03	NA	3.2e-04
17	TCGA	Colon Adenocarcinoma	0.08200	0.0410	4.2e-03	0.002	0.026	0.016	NA	0.015	2.2e-01	1.2e-02	3.9e-02	NA	4.3e-02
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.10620	0.0458	6.9e-06	0.016	0.043	0.031	NA	0.026	5.5e-03	1.3e-05	1.7e-04	NA	5.8e-04
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.03330	0.0179	8.3e-03	0.013	0.011	0.006	NA	0.019	1.3e-02	1.7e-02	6.8e-02	NA	3.0e-03
20	TCGA	Lung Adenocarcinoma	0.09760	0.0467	5.6e-04	0.001	0.017	0.019	NA	0.009	2.5e-01	4.3e-03	2.2e-03	NA	3.0e-02
21	TCGA	Lung Squamous Cell Carcinoma	0.03780	0.0223	7.6e-03	0.036	0.005	0.013	NA	0.027	5.1e-05	8.8e-02	9.9e-03	NA	4.4e-04
22	TCGA	Pheochromocytoma and Paraganglioma	0.20500	0.0930	3.5e-04	0.141	0.093	0.057	NA	0.118	3.0e-06	1.6e-04	2.6e-03	NA	2.0e-05
23	TCGA	Prostate Adenocarcinoma	0.07650	0.0354	2.9e-04	0.034	0.024	0.030	NA	0.034	1.6e-04	1.4e-03	4.0e-04	NA	1.6e-04
24	TCGA	Thyroid Carcinoma	0.09100	0.0380	2.4e-05	0.042	0.052	0.048	NA	0.047	5.2e-05	8.4e-06	1.6e-05	NA	2.0e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Loud music exposure frequency	7.4	8.1	19.1	3.1	2.4	3.1	2.7	3.7	2.2	2.9	2.3	3.1	1.4	3.7	1.7	3.9	4.4	0.7	1.7	-0.1	3.8	1.5	3.4	2.9	3.4	3.8
Medication: Blood pressure	6.1	11.6	22.6	4.1	4.1	4.1	4.1	2.7	2.5	3.3	1.9	4.7	2.2	2.6	2.6	3.0	4.0	2.4	4.0	2.0	4.3	1.3	4.1	4.2	4.8	3.4
Medication: Atenolol	5.8	7.2	15.9	3.4	2.1	3.4	4.0	1.7	2.9	3.3	0.8	2.7	3.3	2.2	1.6	2.3	2.8	3.3	3.1	2.6	2.6	1.1	2.3	3.3	3.7	1.7
Supplements: Vitamin C	5.6	6.6	12.1	-3.3	-2.5	-3.3	-3.2	-2.5	-3.3	-2.7	-1.8	-3.0	-2.3	-3.5	-1.5	-2.2	-2.3	-2.3	-2.8	-1.9	-2.6	0.4	-2.4	-3.1	-3.4	-2.1
Mean Putamen Volume	4.6	5.2	12.5	-2.6	-2.0	-2.6	-1.3	-2.8	-2.4	-3.5	-3.4	-2.3	-0.6	-2.6	-1.1	-2.4	-2.3	0.1	-1.7	-1.1	-2.3	0.8	-3.2	-2.9	-2.7	-2.9
Medication: Ramipril	4.4	5.6	10.3	2.6	2.1	2.6	2.9	2.1	2.1	3.0	2.2	2.7	2.3	2.2	1.2	2.6	3.1	1.7	2.4	1.4	3.2	1.8	2.0	2.8	2.8	2.8
Vascular/heart problems diagnosed by doctor	4.3	11.6	23.1	-3.8	-2.8	-3.8	-4.0	-2.6	-4.8	-3.4	-2.6	-3.8	-3.1	-3.0	-3.1	-4.2	-3.4	-3.5	-3.0	-3.0	-4.6	-0.8	-3.2	-3.6	-3.9	-3.8
High blood pressure	4.2	11.6	27.4	3.8	2.9	3.8	3.8	2.6	5.2	3.4	2.6	3.8	3.4	2.9	3.3	4.2	3.2	3.7	3.1	3.1	4.3	0.3	3.2	3.5	3.9	3.4
Medication: Lisinopril	4.0	5.2	12.3	2.6	3.5	2.6	1.7	2.1	0.9	1.7	1.3	3.4	1.0	1.9	2.6	1.9	2.3	0.1	1.7	2.1	3.0	1.7	2.9	2.9	2.9	2.9
Hypertension (Self-reported)	3.9	10.8	22.5	3.9	3.0	3.9	3.7	2.3	4.7	3.4	2.5	3.9	3.2	2.9	3.2	3.8	3.3	3.4	2.9	2.7	4.2	0.5	3.1	3.6	3.9	3.3
Medication: Aspirin	3.9	5.0	8.9	2.9	2.2	2.9	2.8	2.5	1.4	2.5	0.4	2.8	0.8	2.7	2.5	1.5	2.7	1.0	2.0	1.3	2.9	1.6	2.1	3.0	2.9	2.6
Cardiovascular Disease	3.5	11.6	20.5	3.7	3.9	3.7	3.8	2.7	4.5	3.4	3.4	4.0	2.5	3.6	3.2	4.4	3.4	2.7	2.4	2.6	4.5	0.1	3.3	3.5	3.8	3.8
Mineral and other dietary supplements	3.4	4.6	11.6	2.9	2.3	2.9	2.1	-0.0	2.4	3.4	3.1	2.5	0.6	1.6	2.4	1.8	1.7	0.2	0.8	1.9	2.2	-0.4	2.3	2.7	2.6	2.6
Medication: Bendroflumethiazide	3.4	5.2	8.8	2.4	2.6	2.4	2.9	2.5	2.8	2.3	1.8	2.6	1.9	2.2	2.2	2.2	2.2	1.9	2.6	1.5	3.0	0.0	2.2	2.5	2.6	2.3
Medication: Aspirin	3.2	4.2	7.3	2.6	2.0	2.6	2.6	2.5	1.1	2.4	0.1	2.6	0.7	2.5	1.8	1.3	2.6	0.9	1.9	0.9	2.6	1.5	1.9	2.7	2.7	2.4
Had other major operations	3.0	3.7	13.0	-2.9	-1.2	-2.9	-3.6	-0.8	-1.3	-2.0	-0.4	-2.1	-1.5	-0.9	-0.8	-0.5	-1.9	-1.8	-2.6	-1.2	-1.7	-2.0	-0.9	-3.2	-2.5	-1.3
Supplements: Calcium	2.8	3.1	9.1	-2.5	-1.1	-2.5	-2.8	0.6	-2.2	-1.4	0.4	-1.3	-2.2	-0.1	-2.7	-0.6	-1.1	-2.2	-1.5	-3.0	-0.9	-1.8	-0.7	-2.3	-2.0	-0.4
Systolic Blood Pressure	2.7	13.5	40.3	3.3	2.8	3.3	3.5	3.8	6.3	3.0	3.5	3.4	3.8	4.3	4.3	4.7	2.9	3.8	3.1	4.4	4.6	-0.5	2.9	3.2	3.6	4.1
Taking other prescription medications	2.6	4.1	7.0	2.2	2.0	2.2	1.8	2.3	1.9	2.5	2.1	2.4	1.0	2.6	2.3	2.3	2.6	0.5	1.3	0.4	2.6	0.2	2.1	2.3	2.3	2.5
Financial difficulties in last 2 years	2.5	3.3	9.4	1.9	0.5	1.9	1.9	2.9	3.0	2.2	1.6	1.1	3.1	2.1	-0.9	2.2	1.8	2.8	1.9	0.0	1.1	-0.3	0.5	1.8	1.7	0.5
Medication: Blood pressure	2.4	4.3	10.1	2.3	1.6	2.3	1.9	1.6	2.8	2.8	1.8	2.3	1.4	2.4	2.0	2.3	2.3	0.9	0.9	1.4	3.2	1.0	1.9	2.3	2.2	3.0
Shortness of breath walking on level ground	2.3	2.7	7.2	1.4	1.5	1.4	2.0	1.9	1.7	2.6	1.1	1.1	2.2	2.7	-0.3	1.8	1.9	1.8	2.1	0.7	1.5	0.1	1.5	1.4	1.6	1.6
Nervous feelings	2.2	4.1	12.0	-1.8	-3.5	-1.8	-0.9	-0.9	-2.7	-1.8	-3.0	-2.5	0.1	-2.0	-2.2	-3.1	-1.6	-0.2	-0.4	-1.5	-2.3	1.2	-2.7	-1.7	-2.2	-2.7
Emphysema/chronic bronchitis	2.2	2.5	6.1	-1.4	-0.6	-1.4	-1.8	-1.7	-2.0	-2.5	-0.9	-1.3	-1.8	-2.4	-1.1	-1.8	-1.3	-2.1	-1.7	-1.8	-2.0	-0.5	-0.8	-1.3	-1.6	-1.4
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	10.8	-1.8	-1.0	-1.8	-2.6	0.4	-3.3	-2.4	-0.8	-0.7	-2.3	-2.0	-1.9	-0.8	-1.0	-2.8	-1.7	-1.8	-0.9	-0.4	-0.5	-1.6	-1.3	-0.9
Medication: Amlodipine	2.1	2.9	10.3	1.4	0.7	1.4	1.0	0.6	3.2	2.9	2.1	1.0	1.5	2.9	1.2	3.0	2.0	1.4	0.3	0.7	2.2	0.8	0.2	1.4	1.0	1.7
Illnesses of siblings: Diabetes	2.1	2.5	5.7	-1.0	-1.3	-1.0	-2.3	-0.6	-1.7	-2.0	-0.8	-1.6	-2.3	-1.8	-1.3	-1.6	-1.6	-2.2	-2.4	-0.9	-2.0	-0.7	-1.9	-1.0	-1.6	-1.8
Hearing aid user	2.1	2.3	10.3	-1.7	-0.1	-1.7	-2.5	0.4	-1.9	-1.6	0.6	-0.5	-3.2	-0.4	-1.0	0.0	-0.6	-3.2	-2.6	-1.6	0.3	-0.0	-0.6	-1.4	-1.7	0.6
Supplements: Fish oil (including cod liver oil)	2.1	2.7	11.2	-2.3	-1.9	-2.3	-1.7	0.6	-1.3	-3.4	-1.7	-1.9	-0.1	-2.0	-1.0	-1.0	-1.8	0.4	-0.8	0.1	-1.6	-0.0	-1.9	-2.2	-1.9	-2.0
Maternal smoking around birth	2.0	3.0	10.3	0.9	1.1	0.9	0.7	1.2	3.2	2.0	1.9	0.5	0.9	3.1	1.9	3.2	1.1	2.0	0.5	2.5	2.2	0.2	0.5	0.7	0.9	2.5
Age at first live birth	2.0	3.6	10.3	-1.7	0.9	-1.7	-1.9	-2.3	-2.1	-2.4	-1.6	-0.7	-3.2	-2.5	1.1	-3.2	-2.8	-2.2	-1.6	0.0	-1.8	-2.2	-0.8	-1.4	-1.5	-1.7
Financial situation satisfaction	2.0	2.4	9.9	1.2	1.7	1.2	2.1	0.9	1.8	1.3	0.5	1.2	3.1	1.6	0.4	1.8	1.8	3.0	2.2	0.7	1.4	0.9	0.7	1.1	1.4	0.8
Number of treatments/medications taken	1.9	3.4	7.2	1.9	2.2	1.9	1.9	1.6	2.1	1.9	1.1	2.3	1.4	1.6	2.0	2.2	2.1	1.0	1.6	1.4	2.7	0.9	1.8	2.0	2.2	2.4
Stomach or abdominal pain in last month	1.9	2.3	5.9	-1.9	-1.6	-1.9	-1.7	-0.7	-0.6	-2.4	0.3	-1.6	-0.4	-1.4	-1.6	-0.8	-1.7	-1.2	-1.9	-1.4	-1.5	-1.4	-1.8	-2.0	-2.0	-1.5
Heart attack	1.9	2.5	5.8	1.8	1.4	1.8	1.9	-0.1	0.9	2.1	1.0	1.9	-0.2	1.8	1.5	1.3	1.9	0.5	1.5	1.4	2.3	1.0	1.9	1.8	1.9	2.4
Birth weight of first child	1.9	3.4	13.6	-1.0	-1.7	-1.0	-0.7	-0.9	-3.7	-2.3	-2.2	-1.4	-2.0	-3.2	1.3	-3.0	-1.0	-1.9	-1.4	-2.0	-1.9	1.6	-1.0	-1.1	-1.4	-1.9
Worry too long after embarrassment	1.9	3.2	10.8	-0.8	-1.9	-0.8	-1.2	-0.4	-2.2	-2.8	-1.4	-1.2	-1.9	-3.1	-1.3	-3.3	-2.2	-1.3	-1.3	-1.1	-2.5	-0.9	-1.5	-0.8	-1.2	-2.7
Age at last live birth	1.9	2.8	7.5	-1.5	-0.2	-1.5	-1.5	-2.4	-0.9	-2.4	-1.3	-1.2	-2.2	-2.7	0.4	-2.7	-2.3	-1.3	-1.7	-0.1	-1.7	-1.7	-1.5	-1.4	-1.6	-1.7
Heart attack/myocardial infarction (self-reported)	1.9	2.4	5.5	1.8	1.6	1.8	1.8	0.0	0.9	2.1	1.3	1.9	-0.4	1.9	1.5	1.3	1.7	0.3	1.2	1.6	2.2	0.8	1.9	1.8	1.9	2.4
Coronary Artery Disease (CAD)	1.6	1.9	7.9	1.3	1.8	1.3	1.1	0.1	1.6	1.4	0.6	1.3	0.7	1.0	2.8	1.9	1.1	1.1	0.6	2.0	1.8	0.6	1.0	1.4	1.4	1.7
Systolic blood pressure, automated reading	1.6	4.7	22.8	1.5	0.9	1.5	2.2	1.6	4.8	0.8	1.4	1.6	3.2	1.3	3.9	2.2	0.9	3.2	2.0	3.0	2.2	-1.6	1.2	1.3	1.7	1.3
Qualifications: CSEs or equivalent	1.6	2.1	9.5	-2.1	-3.1	-2.1	-1.4	-0.3	0.8	-1.6	0.1	-2.5	-0.1	-0.5	-1.5	0.7	-0.8	0.3	-1.1	-0.7	-0.5	-0.6	-2.1	-2.1	-2.5	-0.3
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	6.4	-1.8	-1.8	-1.8	-1.4	-1.2	-1.8	-1.8	-2.2	-2.1	-0.0	-1.6	-0.7	-1.7	-1.5	0.4	-0.2	-1.1	-2.3	-0.1	-1.7	-2.1	-2.0	-2.5
Medication for pain relief, constipation, heartburn	1.6	2.7	5.8	-1.1	-1.7	-1.1	-2.2	-1.3	-1.7	-1.9	0.2	-2.1	-2.4	-1.9	-2.1	-1.5	-1.8	-1.9	-2.1	-1.0	-2.1	-0.0	-1.9	-1.2	-2.0	-1.3
Ovarian Cancer	1.5	2.0	10.6	-2.0	-1.9	-2.0	-1.9	0.4	0.2	-1.1	0.0	-1.8	-1.1	0.1	-1.1	0.0	-1.1	-1.0	-1.5	-1.9	-1.2	-3.2	-0.1	-2.0	-1.6	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.4	8.2	-1.6	-1.9	-1.6	-1.1	-1.3	-1.4	-0.7	-1.7	-2.2	1.4	-0.5	-1.6	-1.4	-1.5	0.6	-0.8	-0.5	-1.8	1.4	-2.9	-1.6	-1.9	-2.2
Ulcerative Colitis	1.4	2.0	6.7	1.7	1.0	1.7	1.9	1.6	-0.1	2.6	0.1	1.2	1.8	1.7	0.7	0.8	1.5	1.0	1.7	1.0	1.2	1.9	1.2	1.5	1.6	1.1
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	5.1	-1.1	-1.8	-1.1	-1.2	-0.9	-0.0	-1.8	0.3	-1.1	-1.4	-1.3	0.9	-0.4	-1.7	-1.1	-2.2	0.4	-1.4	-1.6	-1.2	-1.3	-1.0	-1.5
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	6.1	1.4	1.2	1.4	1.4	0.3	0.7	1.8	0.3	0.8	1.6	2.5	-0.5	1.1	0.6	1.8	1.6	1.8	1.0	1.6	0.2	1.5	1.2	1.1
Falls in the last year	1.4	1.9	8.1	0.8	1.9	0.8	2.3	0.9	0.8	0.6	0.4	1.1	2.8	0.4	-1.1	1.4	2.0	2.0	2.4	-0.8	1.3	1.1	0.8	0.9	1.1	0.5
Medication: Lansoprazole	1.4	1.6	4.9	-2.1	-1.3	-2.1	-2.2	-0.3	-0.0	-0.8	0.5	-1.3	-0.9	-0.7	-0.7	-0.0	-1.4	-0.7	-1.9	-0.6	-0.7	-1.5	-1.2	-2.1	-1.8	-0.9
Mother’s age at death	1.4	1.8	5.1	-0.9	-1.5	-0.9	-1.4	-1.4	-1.3	-0.7	-0.5	-1.6	-1.5	-1.5	-1.7	-2.2	-1.7	-0.9	-1.0	-0.7	-2.1	-1.1	-1.3	-0.9	-1.4	-1.6
Number of operations (self-reported)	1.4	2.1	6.7	-1.6	-2.0	-1.6	-2.6	-0.9	-1.6	-1.1	-0.8	-1.9	-1.7	-0.7	-1.2	-1.2	-1.2	-1.6	-1.9	-1.2	-1.5	-0.6	-1.0	-1.7	-1.8	-0.8
Age at First Birth	1.3	1.9	5.2	-0.5	-0.8	-0.5	-0.4	-1.7	-1.9	-2.1	-1.0	-0.8	-1.5	-2.0	0.6	-2.1	-1.2	-1.0	-1.7	-0.9	-1.9	0.5	-1.8	-0.6	-1.0	-2.3
Allergy or Eczema	1.3	3.5	16.2	-1.9	-0.7	-1.9	-2.1	-0.5	-4.0	-2.2	-1.3	-0.7	-1.8	-2.9	-2.8	-1.6	-1.6	-2.9	-1.6	-1.7	-1.8	0.4	-0.7	-1.4	-1.4	-1.6
Sensitivity / hurt feelings	1.3	2.3	8.4	-0.7	-0.7	-0.7	-0.9	-1.1	-1.5	-2.0	-0.7	-1.1	-1.2	-2.9	0.1	-2.7	-1.8	-1.4	-1.5	-1.3	-2.2	-1.2	-1.6	-0.7	-1.1	-2.6
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	10.5	-0.9	0.0	-0.9	-1.1	-0.1	-3.2	-1.2	-0.7	-0.2	-1.4	-1.3	-0.6	-1.4	-0.5	-2.7	-1.1	-2.5	-1.0	0.3	-0.7	-0.6	-0.8	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.4	3.4	-1.2	-1.4	-1.2	-1.0	-1.1	-1.8	-1.0	-1.8	-1.0	-0.4	-1.6	-0.5	-1.1	-1.1	-1.0	-0.4	-1.7	-1.7	-1.5	-0.5	-1.1	-0.8	-1.6
Diastolic blood pressure, automated reading	1.3	3.9	17.8	1.5	1.3	1.5	2.4	1.8	4.2	0.7	1.2	1.8	2.8	1.2	2.7	2.4	1.8	2.8	2.2	0.5	2.4	-1.5	1.4	1.3	1.8	1.6
Schizophrenia vs Biploar Disorder	1.2	1.6	6.7	-1.4	-0.9	-1.4	-1.6	-2.0	-0.8	-1.4	-1.0	-1.6	-0.7	-1.6	-2.6	-1.2	-0.8	-0.4	-0.5	-1.5	-1.3	-0.7	-0.9	-1.3	-1.3	-0.6
Neuroticism	1.2	2.8	10.2	-0.9	-1.4	-0.9	-1.7	-0.1	-2.6	-1.4	-0.9	-1.8	-1.2	-2.1	-1.4	-3.2	-2.0	-1.9	-1.9	-1.0	-2.6	0.4	-1.8	-0.7	-1.5	-2.2
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.7	-1.2	-1.3	-1.2	-0.6	1.5	-1.0	-1.4	-1.4	-1.9	0.7	-0.5	-1.0	-1.5	-0.9	0.2	-0.7	-1.6	-2.0	0.8	-2.0	-1.2	-1.7	-2.2
Vitamin and mineral supplements	1.2	1.7	4.2	1.4	0.8	1.4	1.1	0.8	1.2	1.6	1.6	1.8	-0.1	1.8	0.1	1.2	1.7	-0.1	0.8	0.1	1.6	-0.2	2.0	1.5	1.8	1.8
Supplements: Glucosamine	1.2	1.6	6.3	-1.4	-0.8	-1.4	-0.8	0.3	-2.5	-2.1	-2.4	-1.0	-1.1	-1.2	-0.7	-1.3	-0.2	-1.0	-0.1	-1.9	-0.9	1.4	-0.3	-1.2	-1.2	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	6.7	-1.0	-1.7	-1.0	-0.7	-0.1	-0.9	-0.3	-0.9	-2.0	1.4	-0.0	-1.3	-1.6	-1.7	0.8	-0.5	0.4	-1.7	0.8	-2.6	-1.1	-1.5	-2.0
Suffer from ‘nerves’	1.2	2.0	6.4	-1.0	-0.6	-1.0	0.5	-0.2	-2.3	-1.5	-2.5	-0.9	1.5	-0.9	-1.9	-1.7	-0.1	0.6	1.0	-2.4	-1.7	1.0	-1.2	-0.7	-0.9	-2.5
Osteoarthritis (self-reported)	1.2	1.5	4.1	-1.7	-1.3	-1.7	-0.9	-1.2	-1.4	-1.8	-2.0	-1.6	-0.8	-0.0	-1.0	-0.6	-0.4	-0.2	-0.5	-2.0	-0.8	0.7	-1.4	-1.6	-1.7	-0.7
Commuting to job workplace: Cycle	1.2	1.5	4.5	-1.7	-2.1	-1.7	-1.6	0.7	-0.8	-0.6	0.0	-1.9	-0.8	0.3	-1.4	0.1	-0.3	-0.7	-1.3	-2.0	-0.9	-0.2	-1.5	-1.7	-1.6	-0.6
Waist Hip Ratio (WHR)	1.1	5.1	11.3	1.7	3.1	1.7	2.7	1.4	1.7	1.2	0.1	2.6	1.8	2.2	3.4	3.3	2.6	1.4	2.8	1.5	3.0	0.4	3.2	1.8	2.5	3.1
Chronotype (morning person)	1.1	2.5	5.7	1.6	1.6	1.6	1.2	1.3	1.9	2.4	1.7	1.4	0.9	2.3	2.1	2.1	1.3	1.0	0.6	1.9	1.8	0.4	1.2	1.6	1.6	1.8
Diabetes (father)	1.1	1.3	3.4	0.9	1.0	0.9	0.7	1.0	1.9	-0.4	1.1	1.5	0.1	1.5	1.9	1.7	0.4	0.9	0.5	1.8	1.6	-0.6	1.2	0.8	1.1	1.1
Hayfever, allergic rhinitis or eczema	1.1	2.3	12.7	-1.7	-0.8	-1.7	-1.5	-0.1	-3.6	-2.2	-1.2	-0.8	-0.9	-2.1	-2.3	-1.0	-1.0	-2.1	-0.8	-1.5	-1.4	0.7	-0.3	-1.3	-1.1	-1.1
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.8	-1.6	-1.0	-1.6	-0.9	-0.5	-0.3	-0.9	-1.9	-1.8	1.0	-0.8	-0.2	-0.9	-1.4	0.7	-0.0	0.1	-1.6	-0.6	-1.4	-1.7	-1.4	-1.7
Wheeze or whistling in the chest in last year	1.1	2.0	7.7	1.2	0.9	1.2	1.0	1.3	2.1	0.8	1.7	1.3	1.2	1.9	-0.2	2.8	1.7	1.1	0.9	0.7	1.5	-0.4	2.2	1.1	1.8	1.7
Leg pain on walking	1.1	1.3	7.3	0.4	0.6	0.4	0.7	2.1	0.8	0.3	0.2	0.2	2.0	2.0	-2.7	1.2	1.4	1.7	1.4	-0.5	0.9	0.8	-0.2	0.4	0.4	0.4
Unable to work because of sickness or disability	1.1	1.4	6.2	0.0	0.3	0.0	0.3	-0.3	2.5	0.2	1.2	0.3	1.5	2.4	-1.9	2.1	0.7	1.7	0.8	0.7	1.5	-1.0	-0.1	-0.1	0.4	1.1
Depression (Nagel 2018)	1.0	1.5	4.0	-1.0	-0.7	-1.0	-0.7	0.9	-1.4	-1.1	-1.6	-1.8	0.9	-0.0	-1.5	-1.6	-1.1	0.0	-0.7	-0.7	-2.0	1.0	-2.0	-1.0	-1.4	-1.8
Worry (Nagel 2018)	1.0	2.1	7.0	-1.1	-1.5	-1.1	-0.8	-0.5	-2.6	-1.2	-1.6	-1.1	-0.8	-1.2	-1.8	-2.7	-1.4	-1.2	-1.0	-1.6	-1.7	0.4	-1.7	-1.0	-1.3	-2.1
Alzheimer’s Disease (in father)	1.0	1.0	8.6	-0.9	-0.9	-0.9	-0.9	0.7	-1.4	-1.3	-1.0	-0.5	-0.3	-1.0	-1.5	0.1	0.6	-0.9	-0.5	-2.9	-0.5	-0.2	-0.2	-1.0	-0.5	-0.9
Irritable Bowel Disease (IBD)	1.0	2.4	4.7	2.2	1.7	2.2	1.9	1.2	1.4	1.6	0.8	1.7	1.7	1.3	1.8	1.6	1.5	1.3	1.1	1.7	1.3	0.6	1.6	1.9	2.1	1.1
HbA1C	1.0	1.1	3.4	-1.2	-0.4	-1.2	-1.1	0.8	-0.7	-0.8	-0.3	-0.5	-1.6	0.4	-1.0	-0.8	-1.2	-0.9	-1.4	-1.9	-0.9	-1.6	-0.4	-1.6	-1.1	-1.2
Heel T-Score	1.0	8.1	33.3	2.8	3.8	2.8	2.9	1.0	2.1	4.3	-0.0	3.8	1.5	3.1	5.8	1.9	2.2	1.7	3.1	2.2	3.1	0.1	3.2	3.0	3.5	2.3
Hearing difficulty/problems: Yes	1.0	1.6	4.2	-1.5	-0.6	-1.5	-1.2	-0.4	-1.0	-1.8	-1.4	-0.3	-1.5	-1.8	-0.3	-2.1	-1.7	-1.1	-0.6	-1.3	-1.0	-1.8	-0.7	-1.3	-1.1	-1.3
Supplements: Zinc	1.0	1.1	6.1	-0.8	-0.5	-0.8	-0.4	0.3	-2.0	-1.3	-0.7	-0.8	-0.2	-0.5	-2.2	0.3	0.3	-0.5	-0.6	-2.5	0.1	1.8	-0.8	-1.1	-1.0	-0.1
Pack years adult smoking proportion	1.0	1.5	4.8	0.9	0.0	0.9	0.4	1.4	1.4	1.6	2.2	0.3	-1.1	1.9	1.1	2.1	1.5	-0.4	-1.1	-0.2	1.6	0.5	0.5	0.6	0.5	2.1
Average weekly fortified wine intake	1.0	1.2	5.1	-1.2	-0.9	-1.2	-0.8	-0.0	-1.9	-0.9	-2.3	-1.0	0.1	-1.2	-0.0	-1.8	-0.9	-0.6	-0.1	-0.9	-1.0	0.9	-1.4	-1.0	-1.1	-1.5
Neuroticism score	1.0	2.0	7.8	-0.4	-1.7	-0.4	-0.7	-0.2	-2.3	-1.1	-1.4	-1.6	-0.5	-1.7	-1.2	-2.8	-1.3	-1.1	-1.0	-1.2	-2.3	0.6	-1.7	-0.3	-1.0	-2.3
Mood swings	1.0	1.9	8.2	-0.8	-1.2	-0.8	-1.2	-0.0	-1.0	-0.0	-0.7	-2.4	-0.5	-1.0	-1.0	-1.6	-1.5	-0.7	-1.9	-1.0	-2.2	0.4	-2.9	-0.7	-1.8	-2.0
Medication: Atorvastatin	1.0	1.2	3.8	1.3	1.9	1.3	1.1	0.9	0.6	1.4	1.5	1.6	-0.4	1.3	1.0	0.8	0.8	-0.6	0.2	0.3	1.1	0.1	1.1	1.5	1.5	1.3
Age started oral contraceptive pill	1.0	1.2	3.8	-1.0	-0.8	-1.0	-1.2	-1.9	-1.7	-0.8	-0.9	-0.5	-1.0	-1.9	-0.2	-1.9	-1.7	-0.4	-0.3	1.3	-0.2	0.5	-0.9	-1.0	-1.0	-0.3
Ever depressed for a whole week	1.0	1.3	13.3	-0.2	-1.0	-0.2	-0.1	-1.4	-1.7	0.8	-1.5	-0.9	1.2	0.4	-1.8	-0.4	-0.2	0.6	0.3	1.0	-0.5	3.7	-0.9	-0.1	-0.6	-0.2
Bipolar Disorder or Schizophrenia	0.9	2.2	5.9	-1.5	-1.0	-1.5	-1.8	-0.9	-1.9	-2.4	-0.7	-1.8	-0.4	-2.0	-0.7	-1.1	-1.7	-0.8	-1.6	0.8	-2.0	0.7	-2.2	-1.2	-1.6	-1.8
Primary Biliary Cirrhosis	0.9	1.3	5.5	0.7	1.6	0.7	0.6	0.8	1.3	-0.4	1.6	1.4	-0.2	-0.2	2.2	1.4	-0.2	0.7	0.4	2.3	1.3	-0.5	1.3	0.5	1.1	1.5
Blood White Count	0.9	6.5	24.1	2.1	2.7	2.1	0.8	1.1	4.1	1.6	3.2	2.8	0.6	2.9	2.9	3.3	0.9	1.5	1.3	4.9	3.3	-1.4	2.9	2.2	2.5	3.4
Hypothyroidism (self reported)	0.9	2.0	5.6	-2.4	-1.2	-2.4	-2.0	-0.8	0.3	-1.8	0.5	-1.8	-0.5	-0.7	-0.7	1.1	-1.2	-0.9	-1.7	-1.2	-0.5	-2.3	-1.1	-2.2	-1.9	-0.3
Lung FVC	0.9	4.7	16.6	-2.0	-0.8	-2.0	-2.0	-1.0	-3.7	-3.0	-1.8	-1.3	-1.3	-4.1	-2.2	-3.2	-2.4	-1.5	-1.3	-1.3	-2.3	1.0	-2.3	-1.9	-2.1	-2.8
Alcohol usually taken with meals	0.9	1.4	6.1	-1.0	-0.1	-1.0	-1.3	-0.8	-0.6	-1.1	-0.1	-0.4	-2.4	-1.0	1.2	-1.4	-1.7	-1.3	-1.3	-0.6	-1.3	-2.5	-0.1	-0.7	-0.8	-1.1
Had menopause	0.9	1.2	3.7	-0.8	-1.3	-0.8	-1.1	-1.2	-0.8	-1.0	-0.7	-1.0	-1.0	-1.9	-0.4	-1.9	-1.4	-1.0	-1.3	-0.4	-1.3	-1.0	-1.0	-0.9	-0.9	-1.0
Time employed in main current job	0.9	1.1	4.8	0.4	1.8	0.4	-0.4	-0.2	-1.9	-0.3	0.4	0.7	-1.8	-0.6	-1.3	-1.0	0.5	-2.1	-0.5	-2.2	-0.1	0.0	0.7	0.6	0.5	0.4
Asthma	0.9	1.8	6.3	1.3	2.0	1.3	1.6	2.5	1.1	1.6	0.8	1.5	1.7	1.3	-0.1	1.2	1.3	1.0	1.4	0.1	0.8	-0.6	2.2	1.1	1.7	0.7
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	4.9	-1.7	-0.8	-1.7	-2.2	-0.9	0.2	-1.2	1.6	-1.2	-1.7	-0.4	0.1	1.3	-0.7	-1.8	-2.2	-1.0	0.1	-1.9	-0.4	-1.6	-1.4	0.7
Forced vital capacity (FVC), Best measure	0.9	3.4	12.3	-2.0	-1.2	-2.0	-0.8	-1.6	-3.4	-2.8	-1.8	-1.2	-0.3	-3.5	-0.4	-2.5	-2.0	-0.8	-1.0	-1.4	-1.8	0.8	-1.5	-2.0	-1.9	-2.4
Number of full brothers	0.9	1.1	9.6	0.5	-1.1	0.5	0.0	-0.6	1.8	0.4	1.6	-0.2	0.8	1.1	0.1	1.2	-0.1	1.5	0.4	3.1	0.7	0.6	0.2	0.4	0.3	1.4
Pulse wave peak to peak time	0.9	1.0	2.9	-1.0	-1.3	-1.0	-1.2	0.6	-1.2	-0.8	-0.4	-0.5	-1.0	-0.7	0.0	-1.7	-1.1	-1.3	-1.3	-1.4	-0.7	-0.9	-1.0	-0.7	-1.1	-1.2
Medication: Ibuprofen	0.9	1.1	6.6	0.4	-0.0	0.4	1.7	-1.7	1.7	0.4	-1.0	0.1	1.8	0.3	0.7	0.5	0.8	2.6	1.7	0.6	0.3	-0.2	0.0	0.5	0.5	-0.4
Chest pain or discomfort	0.9	1.2	2.8	-1.6	-1.0	-1.6	-0.3	-0.2	0.4	-1.4	-0.9	-1.5	1.7	-0.5	-1.1	0.1	-1.3	1.2	-0.2	-0.5	-1.2	-1.0	-1.4	-1.4	-1.3	-1.4
Family relationship satisfaction	0.9	1.1	7.5	1.5	0.7	1.5	1.3	1.3	-0.8	0.6	-0.0	0.4	0.8	0.7	-1.1	0.6	1.6	0.8	0.7	-0.3	0.3	2.7	-0.2	1.2	0.9	0.3
Average weekly red wine intake	0.9	1.3	7.3	0.0	0.2	0.0	-0.8	-0.5	-1.9	-0.7	-0.4	-0.1	-2.3	-1.1	-0.4	-2.7	-1.4	-2.0	-1.4	-0.7	-1.3	-0.1	-0.9	0.1	-0.5	-0.8
Asthma (self-reported)	0.9	1.8	5.7	1.3	1.9	1.3	1.8	2.4	1.0	1.6	0.6	1.4	1.7	1.1	-0.3	1.3	1.6	1.1	1.5	-0.2	0.9	-0.2	2.1	1.1	1.6	0.8
Commuting to job workplace: Public transport	0.9	1.1	3.7	1.4	0.6	1.4	0.8	1.1	0.3	1.9	-0.4	1.2	1.3	1.2	1.4	-0.6	0.1	0.6	1.0	1.7	0.2	0.2	0.7	1.1	1.4	-0.3
Pain type(s) experienced in last month: Hip pain	0.9	1.1	5.0	-0.2	-2.2	-0.2	0.3	-0.9	0.7	-0.5	-0.7	-1.4	1.7	0.1	-1.6	-0.6	-0.8	1.5	0.1	0.7	-1.6	-0.1	-1.5	-0.0	-0.5	-1.5
Alcohol drinker status: Never	0.9	1.0	5.6	-0.9	-0.6	-0.9	-0.6	-0.6	-1.1	-0.3	1.0	0.2	-2.4	-1.1	-0.6	-0.3	-0.5	-1.7	-1.5	-1.6	0.9	-1.0	-0.3	-1.2	-1.1	0.8
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	4.8	-0.3	-1.4	-0.3	-1.4	-1.4	0.3	0.0	0.3	-1.1	-2.2	-1.3	-0.4	-1.6	-1.1	-1.6	-1.2	-0.5	-1.0	-1.6	-0.2	-0.5	-0.8	0.4
Pack years of smoking	0.9	1.3	4.5	0.8	-0.3	0.8	0.1	1.1	1.2	1.6	2.0	0.2	-1.5	1.7	0.4	1.8	1.4	-0.8	-1.2	-0.5	1.5	0.6	0.3	0.6	0.3	2.1
Schizophrenia (2018)	0.8	1.6	4.2	-1.0	-1.2	-1.0	-1.5	-1.4	-1.8	-2.0	-0.3	-1.8	-0.6	-1.8	-1.3	-0.5	-0.6	-0.6	-1.2	-0.1	-1.2	1.6	-2.0	-0.6	-1.4	-0.8
Reaction Time	0.8	1.5	4.0	1.2	1.9	1.2	1.4	2.0	1.4	1.8	0.6	1.5	0.6	1.3	0.8	0.6	1.2	0.4	1.3	-0.2	1.1	-0.8	1.5	1.4	1.4	1.0
Number of incorrect matches in round	0.8	1.4	4.6	-1.6	-1.4	-1.6	-0.2	-1.0	-0.9	-0.4	-2.1	-1.3	1.4	-1.0	0.7	-0.9	-1.1	1.0	-0.0	0.8	-0.8	1.3	-1.0	-1.9	-1.2	-1.2
Mouth/teeth dental problems	0.8	1.2	3.9	-1.2	-0.4	-1.2	-0.5	0.6	-0.6	-1.5	-1.9	-0.3	1.5	-0.7	0.8	-1.3	-2.0	0.7	0.3	1.1	-1.2	-0.8	-0.4	-1.3	-0.8	-1.6
Pain all over the body in last month	0.8	0.9	4.6	-1.1	-0.3	-1.1	-0.9	-0.1	-0.9	-1.6	-0.7	-0.4	0.7	0.2	-1.8	0.4	0.1	0.3	-0.5	-2.1	-0.5	0.2	-1.0	-1.2	-0.8	-1.3
Happiness	0.8	1.0	3.2	1.8	1.4	1.8	1.5	-0.2	-0.2	1.3	-0.3	0.6	1.1	0.4	0.2	-0.2	1.1	1.1	0.7	-0.1	0.0	1.4	0.4	1.4	1.2	-0.2
Pulse wave reflection index	0.8	1.0	3.2	1.4	1.8	1.4	1.2	-0.7	-0.6	0.4	0.2	1.0	-0.4	0.1	0.7	0.4	1.0	-0.3	1.1	1.0	0.5	1.2	1.0	1.4	1.5	1.2
Health satisfaction	0.8	1.0	6.7	-0.4	-0.8	-0.4	-0.3	0.4	1.4	0.6	0.6	-1.3	1.1	0.8	-2.6	0.3	-0.3	0.7	-1.0	-1.0	-0.6	-0.3	-2.1	-0.7	-1.3	-0.8
Mean time to correctly identify matches	0.8	1.5	4.4	1.4	2.1	1.4	0.8	1.1	1.5	1.7	1.2	1.7	-0.2	0.9	1.1	0.2	0.6	-0.4	0.7	0.5	1.2	-1.1	1.5	1.7	1.5	1.4
Smoking status: Previous	0.8	1.2	4.1	1.1	0.1	1.1	-0.2	0.2	-0.1	1.4	1.8	1.1	-1.9	0.6	0.2	0.5	1.1	-1.7	-0.7	-1.1	1.2	0.2	1.3	1.1	1.0	2.0
Long-standing illness, disability or infirmity	0.8	1.2	5.9	0.5	0.7	0.5	0.9	1.4	1.6	0.9	1.3	0.5	1.7	2.4	-1.3	1.7	1.1	1.1	0.3	0.4	1.1	0.5	-0.3	0.6	0.6	0.8
Medication for cholesterol	0.8	1.2	2.8	-1.4	-1.7	-1.4	-1.6	-1.2	-1.0	-0.1	-0.4	-1.6	-0.3	-0.0	-1.3	-0.5	-0.8	-0.7	-1.3	-1.1	-1.4	0.2	-1.1	-1.4	-1.5	-1.1
Miserableness	0.8	1.3	4.1	1.9	-0.4	1.9	1.8	1.3	1.3	1.5	0.2	0.3	2.0	0.7	0.6	0.5	0.9	1.6	0.8	0.5	0.0	1.0	-0.3	1.8	1.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.6	-1.2	-0.6	-1.2	-1.7	-0.1	-0.4	-0.8	0.9	-0.8	-1.0	-0.0	0.7	-0.2	-1.4	-1.5	-1.9	-0.5	-0.8	-1.4	-0.5	-1.2	-1.2	-0.5
Alcohol drinker status: Previous	0.8	0.9	3.6	0.3	1.6	0.3	0.8	-0.9	0.7	0.7	1.0	1.3	0.5	0.9	1.9	1.0	0.6	0.1	0.4	1.4	1.5	0.2	0.8	0.4	0.8	1.2
Bipolar Disorder (2018)	0.7	1.1	3.9	-1.2	-0.1	-1.2	-1.1	0.2	-0.8	-1.4	-0.8	-0.6	0.1	-0.9	0.6	-1.1	-2.0	-0.5	-1.0	1.3	-1.6	-0.9	-0.9	-1.1	-0.8	-2.0
Crohns Disease (2017)	0.7	1.5	5.1	1.6	1.4	1.6	1.2	-0.2	2.1	1.0	0.8	1.1	0.7	0.9	2.3	1.4	0.9	1.2	0.2	1.6	1.1	-0.0	0.8	1.3	1.3	0.9
Ulcerative Colitis (UC)	0.7	1.4	3.6	1.5	1.1	1.5	1.7	1.9	0.0	1.5	0.4	1.4	1.5	1.0	0.9	0.5	0.9	0.7	1.2	1.2	0.6	0.8	1.5	1.3	1.7	0.4
Rheumatoid Arthritis	0.7	1.0	3.6	1.2	0.7	1.2	-0.5	-0.5	-0.5	0.8	1.7	0.5	-1.7	0.8	0.5	0.1	0.5	-1.9	-1.5	0.9	0.8	1.1	0.6	1.1	0.6	1.6
Schizophrenia (2014)	0.7	1.5	4.0	-0.8	-0.4	-0.8	-1.6	-0.9	-1.8	-1.9	-0.4	-1.6	-0.6	-2.0	-1.0	-1.4	-0.8	-1.0	-1.5	-0.2	-1.5	1.3	-1.9	-0.6	-1.3	-1.2
Angina	0.7	0.9	3.6	0.2	-0.1	0.2	1.4	-0.2	1.2	1.8	-0.2	0.5	0.8	1.9	0.4	1.4	0.9	1.1	1.2	0.8	1.2	0.2	0.9	0.5	0.6	1.5
Medication: Co-codamol	0.7	0.9	4.7	0.9	-0.0	0.9	-0.1	0.0	2.2	-0.0	1.8	0.6	-0.2	1.1	0.0	1.5	0.4	0.6	-0.0	1.1	1.3	-1.1	0.4	0.6	0.6	1.3
Diabetes (mother)	0.7	1.0	3.2	1.3	1.0	1.3	0.4	0.2	0.8	1.3	0.8	1.1	-0.9	-0.3	1.2	-0.7	0.4	-1.8	-0.5	0.2	0.4	-1.5	1.4	1.1	1.0	1.0
Severe depression (siblings)	0.7	0.8	2.9	-0.4	-1.5	-0.4	-0.4	-0.3	-0.9	-0.8	0.4	-1.5	-0.4	-0.6	-1.7	0.2	-0.0	-0.4	-1.7	-0.8	-1.4	0.9	-1.1	-0.6	-0.9	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	4.5	-0.1	-0.7	-0.1	0.9	-0.0	-0.1	-0.6	-1.7	-1.1	2.1	-0.1	-0.4	-1.1	-0.4	1.4	0.3	-0.6	-1.6	0.8	-1.5	-0.2	-0.6	-1.9
Forced vital capacity (FVC)	0.7	2.6	10.0	-1.3	-0.6	-1.3	-0.6	-1.5	-3.2	-2.6	-1.6	-0.8	-0.5	-3.1	-1.2	-2.4	-1.2	-1.0	-0.5	-1.5	-1.7	1.4	-1.2	-1.2	-1.3	-1.8
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	6.2	0.6	0.1	0.6	1.4	0.1	1.0	0.5	-0.4	-0.4	2.5	1.5	-0.4	1.3	1.4	1.8	0.8	-0.6	0.2	1.9	-1.1	0.5	-0.0	-0.1
Pulse wave Arterial Stiffness index	0.7	0.8	2.0	0.9	1.3	0.9	1.2	-0.6	0.9	0.7	0.3	0.4	0.9	0.6	-0.2	1.4	0.9	1.2	1.2	1.2	0.6	1.0	0.8	0.6	1.0	1.0
Exposure to tobacco smoke at home	0.7	0.8	4.5	-0.4	-0.6	-0.4	-1.1	-2.1	0.5	-0.1	1.1	-1.0	-1.0	-0.7	0.3	0.0	-0.8	-0.5	-1.3	2.1	-0.0	0.3	-0.5	-0.5	-0.7	0.8
Blood clot in the leg (DVT)	0.7	0.8	3.2	-0.2	-1.6	-0.2	-1.1	-1.1	0.5	-0.2	0.4	-1.1	-1.8	-1.3	-0.6	-1.2	-0.7	-1.3	-1.0	-0.6	-0.8	-1.3	-0.3	-0.4	-0.7	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	7.7	-0.2	0.3	-0.2	-0.8	-0.5	-2.8	0.5	-1.2	0.4	-1.4	-0.6	-0.1	-0.7	0.4	-1.3	0.2	-0.9	0.1	0.9	1.3	0.1	0.3	0.3
Qualifications: College or University degree	0.7	2.2	8.9	-1.0	0.7	-1.0	-1.6	-1.2	-3.0	-1.6	-2.2	-0.3	-2.0	-1.9	-0.1	-2.7	-2.0	-2.1	-0.5	-0.3	-1.8	0.1	-0.3	-0.7	-1.0	-1.5
Eye problems/disorders: None of the above	0.7	0.8	3.8	1.1	0.3	1.1	0.9	1.2	1.2	0.9	1.9	0.6	-0.8	0.9	0.3	0.5	0.9	-0.5	-0.4	-0.5	0.8	0.2	0.7	1.0	0.6	1.2
Angina (self-reported)	0.7	0.9	4.0	0.3	0.3	0.3	1.4	-0.1	1.2	2.0	-0.0	0.7	0.7	1.7	0.5	1.4	0.9	0.9	1.0	0.9	1.2	0.2	0.8	0.6	0.7	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.5	0.9	0.3	0.9	1.6	0.3	0.2	1.3	-0.2	0.9	1.2	1.4	0.9	0.7	0.9	1.0	1.4	-0.4	0.7	1.1	0.9	0.9	0.8	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.9	0.5	0.8	0.5	-0.3	-0.9	-0.6	1.3	-0.5	1.0	-1.2	-0.1	1.0	-0.7	0.7	-1.7	0.3	-1.5	0.5	-0.7	1.5	0.8	0.8	0.6
Illnesses of father: None of the above (group 1)	0.7	0.9	3.9	-1.1	-0.6	-1.1	-0.6	-0.1	-1.5	-0.7	-2.0	-0.3	0.6	-0.3	-1.6	-1.5	-0.4	0.3	0.5	-1.2	-0.8	0.6	-0.4	-0.8	-0.7	-1.4
Number of self-reported non-cancer illnesses	0.7	1.2	3.0	1.6	1.2	1.6	1.6	0.5	0.2	1.2	0.7	1.1	0.8	0.4	0.7	1.1	1.7	-0.2	0.4	-0.4	1.0	1.1	1.3	1.7	1.6	1.1
Guilty feelings	0.7	1.0	4.9	1.2	-0.5	1.2	0.7	-0.0	-1.3	0.0	-1.2	-0.5	-0.2	-1.5	1.1	-2.2	-0.2	-0.2	0.5	0.6	-1.5	1.6	-0.2	1.2	0.5	-1.0
Illnesses of father: High blood pressure	0.7	0.8	2.9	0.6	0.9	0.6	0.8	1.6	0.6	-0.2	0.6	0.6	1.7	0.3	1.2	1.6	0.8	0.9	0.6	1.4	1.0	1.0	0.4	0.5	0.6	0.7
Alzheimer’s Disease (including proxy)	0.6	0.8	4.0	-0.6	-0.2	-0.6	-0.1	-0.2	-1.7	-1.8	-2.0	-0.1	0.5	-2.0	-0.5	0.1	0.1	0.1	0.5	-0.9	-1.1	0.3	0.1	-0.6	-0.0	-1.4
Verbal and Numeric Reasoning (VNR)	0.6	1.4	7.5	0.4	-0.5	0.4	1.1	-0.1	-1.3	1.1	-2.7	0.3	1.8	0.6	-0.9	0.2	1.6	1.1	2.2	-1.6	0.1	2.2	0.6	0.6	0.6	-0.3
Hand grip strength (right)	0.6	1.7	4.6	-1.5	-1.3	-1.5	-1.1	-1.0	-0.9	-2.1	-1.7	-1.6	0.1	-1.7	0.5	-1.4	-1.9	0.3	-0.3	0.1	-1.5	-0.2	-1.3	-1.7	-1.6	-1.7
Medication: Levothyroxine sodium	0.6	0.9	4.1	-1.2	-0.7	-1.2	-1.4	-0.8	0.4	-0.7	1.1	-0.4	-1.2	-0.5	0.2	0.9	-0.2	-1.2	-1.2	-1.7	0.3	-2.0	0.0	-1.2	-0.8	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	9.9	1.0	0.5	1.0	0.9	-0.4	1.3	1.0	-0.5	1.0	0.6	1.1	3.2	0.2	0.5	0.9	1.5	1.2	0.6	-1.2	1.7	1.0	1.2	0.2
Fluid intelligence score	0.6	1.3	4.0	1.4	1.1	1.4	1.5	0.2	-0.4	1.5	-1.7	1.2	1.3	0.7	1.3	0.2	1.2	1.1	2.0	-0.2	0.4	1.4	1.1	1.4	1.4	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	5.0	0.2	-0.2	0.2	1.4	-1.3	1.3	0.6	-0.9	-0.2	1.9	0.2	0.8	0.1	0.2	2.2	1.3	0.8	-0.3	-0.3	-0.4	0.2	0.3	-0.8
Depression (self-reported)	0.6	0.7	4.0	0.2	-0.6	0.2	1.0	0.5	-0.1	-0.2	-0.6	-0.4	2.0	0.9	-1.2	0.1	0.1	1.9	0.9	0.3	-0.2	1.4	-1.0	-0.0	-0.0	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	7.5	-1.5	-0.6	-1.5	-0.3	-1.7	-2.3	-2.5	-1.1	-0.5	-0.1	-2.7	-0.1	-1.4	-1.2	-0.4	-0.6	-1.2	-1.0	0.1	-1.0	-1.5	-1.2	-1.7
Tense / ‘highly strung’	0.6	1.0	5.7	-0.1	-1.4	-0.1	-0.6	0.4	-2.1	-0.8	-0.3	-0.9	-0.8	0.9	-1.9	-1.2	0.2	-1.2	-0.4	-0.6	-0.4	2.4	-1.2	0.1	-0.7	0.3
Headache pain in last month	0.6	1.1	4.6	-0.9	-0.4	-0.9	-0.1	-2.1	-1.8	-0.5	-1.2	-0.6	-0.2	-1.0	-0.8	-0.9	0.1	-0.6	-0.8	-2.1	-0.8	0.8	-0.9	-1.1	-0.8	-1.4
Gout (self-reported)	0.6	0.8	4.7	0.5	-1.0	0.5	-0.8	0.3	-0.0	0.1	2.2	-0.1	-1.9	-0.6	-0.3	-0.2	-0.8	-1.8	-1.1	0.4	-0.3	-1.2	-0.1	0.7	0.1	0.7
Medication: Allopurinol	0.6	0.8	5.8	0.8	-0.7	0.8	-0.4	-0.3	1.4	0.6	2.4	0.1	-1.2	0.1	0.8	0.3	-0.8	-0.8	-0.9	1.2	0.1	-1.6	-0.0	0.9	0.2	0.9
Medication: Seretide 50 evohaler	0.6	0.7	2.2	0.9	1.4	0.9	0.6	1.2	1.0	1.2	0.8	1.0	-0.4	0.1	0.5	0.9	0.2	-0.7	-0.0	0.6	0.1	-0.9	1.5	0.8	1.0	0.6
Pulse rate, automated reading	0.6	1.8	9.0	-1.3	-1.1	-1.3	-0.4	-0.8	0.5	-1.6	-1.9	-1.1	1.7	-0.3	-2.0	0.6	0.4	1.6	-0.0	-3.0	-0.7	-0.3	-1.7	-1.7	-1.2	-1.8
Overall health rating	0.6	1.3	3.7	1.3	1.2	1.3	0.9	0.5	1.7	1.3	1.9	1.1	1.3	1.3	0.2	1.8	1.3	0.5	0.1	0.5	1.4	0.7	0.4	1.2	1.2	1.3
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.1	-0.8	-0.9	-0.8	-1.2	1.0	-1.2	0.0	0.5	-0.5	-1.1	-0.2	-0.4	-0.4	-0.6	-1.5	-1.5	-1.1	-0.7	-0.2	-0.4	-0.7	-0.7	-0.7
Ever had bowel cancer screening	0.6	0.7	1.8	0.9	0.6	0.9	0.2	-0.3	1.1	0.6	1.0	0.4	0.8	0.9	0.7	1.2	0.7	0.8	0.5	1.3	1.0	0.7	0.3	0.9	0.8	1.1
Qualifications: nursing, teaching	0.6	0.9	4.5	0.2	0.7	0.2	1.1	-1.4	-1.5	-0.3	-2.1	0.9	1.4	-0.1	0.3	-0.7	0.7	0.9	1.8	-0.4	0.0	1.6	0.5	0.4	0.7	-0.8
Commuting to job workplace: Walk	0.6	0.6	2.4	-1.1	-0.5	-1.1	-0.7	-1.0	-0.8	-0.2	-0.4	-0.3	0.4	-0.8	-0.6	-0.5	-1.5	0.4	0.1	0.3	-0.8	-0.5	-0.6	-1.0	-0.7	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.2	1.0	1.1	1.0	1.6	-0.3	-0.1	0.5	0.5	1.3	-0.7	-0.3	0.9	0.9	1.8	-0.2	1.1	-0.6	1.3	0.5	1.3	1.3	1.4	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.4	0.1	1.1	0.1	0.9	-0.0	1.2	1.1	0.0	0.9	0.7	1.0	1.1	0.6	0.8	0.8	1.1	0.0	1.4	-0.6	1.5	-0.1	0.8	1.0
Medication: Gliclazide	0.6	0.6	2.2	0.7	0.7	0.7	1.1	1.1	0.4	0.8	0.3	0.8	0.2	0.9	-0.2	1.3	1.5	-0.1	0.5	-0.8	0.6	-0.5	0.8	0.9	1.2	0.8
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.8	0.3	0.4	0.3	-0.9	-0.9	-0.0	-0.5	0.4	0.9	-1.2	-0.2	0.6	-1.1	-1.7	-1.3	-1.2	1.7	-0.3	-1.4	0.4	0.1	0.2	-0.2
Neuroticism (Nagel 2018)	0.5	1.1	3.7	-0.3	-1.2	-0.3	-0.8	-0.3	-1.2	-0.6	-0.5	-1.4	-0.7	-1.1	-0.9	-1.7	-1.2	-0.6	-1.4	-0.7	-1.6	0.2	-1.9	-0.4	-0.9	-1.8
Neuroticism (2016)	0.5	0.7	2.2	-0.1	-1.0	-0.1	-1.2	0.4	-0.4	-0.7	0.8	-1.0	-1.0	-1.2	-0.5	-1.0	-1.2	-1.2	-1.5	0.2	-0.9	-0.0	-1.3	-0.3	-0.9	-0.8
Hand grip strength (left)	0.5	1.2	3.5	-1.0	-1.4	-1.0	-1.0	-0.8	-0.8	-1.5	-0.6	-1.6	0.1	-1.4	0.9	-1.0	-1.9	0.0	-0.8	0.6	-1.6	0.0	-1.2	-1.1	-1.4	-1.3
Relative age of first facial hair	0.5	1.0	4.0	-0.7	0.6	-0.7	-0.3	0.4	-1.5	-1.3	-1.1	-0.1	-0.9	-1.6	0.1	-1.6	-0.6	-1.1	-0.6	-2.0	-1.3	-0.7	-0.3	-0.6	-0.5	-1.7
Ever had hysterectomy (womb removed)	0.5	0.6	4.0	0.8	0.4	0.8	0.8	0.4	0.7	0.3	1.2	0.8	-0.5	0.3	0.3	2.0	1.1	0.4	0.4	-0.2	1.1	0.0	0.8	0.6	0.8	0.7
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.9	0.3	0.1	0.3	0.5	0.1	1.2	0.9	1.2	0.0	1.1	0.9	-1.7	1.0	0.5	0.7	0.3	-0.3	0.7	0.2	-0.8	0.3	0.2	0.7
Serious illness, injury or assault to yourself	0.5	0.6	4.0	0.7	-0.3	0.7	0.0	0.5	1.1	0.2	2.0	0.2	0.6	1.8	-0.2	1.1	0.6	0.4	0.0	0.8	0.8	-0.2	0.2	0.5	0.5	1.2
Hair/balding pattern: Pattern 2	0.5	0.6	1.5	-1.1	-1.1	-1.1	-0.7	-0.3	0.1	-0.9	-0.1	-1.2	0.0	0.3	0.1	-0.1	-1.1	0.7	-0.2	0.1	-0.8	-1.1	-1.1	-1.1	-1.1	-0.8
Qualifications: None of the above	0.5	1.1	6.7	-0.4	-1.0	-0.4	-0.5	-0.4	2.6	0.0	1.5	-1.3	0.5	-0.2	0.2	0.9	-1.0	0.7	-1.5	1.8	-0.1	-1.9	-1.4	-0.8	-0.7	0.3
Illnesses of siblings	0.5	0.7	3.8	-0.1	0.2	-0.1	-0.1	1.8	-0.7	1.9	0.3	-0.0	0.0	1.6	-1.3	0.3	0.6	-0.4	0.5	-0.9	0.2	0.6	0.9	0.2	0.1	0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.0	6.4	-1.0	0.1	-1.0	-0.5	-2.5	-1.3	-0.6	-1.5	-0.3	0.8	-1.2	-0.6	-0.8	-0.7	0.5	0.9	-0.2	-1.4	-0.6	-0.1	-0.7	-0.4	-2.0
Prospective memory result	0.5	0.7	2.5	0.1	-1.3	0.1	0.4	1.6	0.9	0.2	-0.9	-1.0	1.1	0.6	0.7	-0.5	-0.4	1.5	0.4	1.2	-0.5	-0.0	-1.4	0.1	-0.3	-0.6
Lung cancer (father)	0.5	0.6	5.4	-0.2	-0.5	-0.2	0.8	-0.3	-1.0	0.2	-0.6	-0.6	1.1	-0.9	-0.1	-0.4	-0.2	0.3	-0.1	-0.2	-0.6	2.3	-1.1	-0.4	-0.6	-0.8
Breastfed as a baby	0.5	0.6	6.5	-0.3	0.2	-0.3	-0.2	-0.8	1.0	-1.2	-0.2	0.6	-0.2	-1.5	0.4	-0.5	-0.6	0.3	0.4	-0.2	0.1	-2.5	0.7	-0.4	0.2	-0.3
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.1	-0.8	-1.4	-0.8	-0.4	-1.1	-0.1	-0.2	-0.3	-1.4	0.7	-0.1	-0.4	-0.3	-1.0	0.5	-0.7	0.9	-1.2	0.2	-1.2	-0.9	-0.7	-0.9
Medication: Paracetamol	0.5	0.9	5.9	-0.1	0.3	-0.1	1.0	-1.0	0.8	1.0	-0.7	0.7	2.4	0.7	-0.4	0.8	1.1	1.7	1.7	0.2	0.9	0.2	0.9	-0.1	0.6	0.2
High blood pressure (siblings)	0.5	0.7	2.0	1.1	-0.0	1.1	1.2	-0.3	1.1	-0.7	0.2	1.0	0.7	-0.5	1.4	0.8	1.3	1.1	1.0	0.1	1.1	0.3	0.3	1.0	1.0	0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	4.6	0.2	-1.3	0.2	0.0	-0.5	0.3	0.1	0.7	-0.9	-0.1	0.8	-2.1	0.4	0.6	-0.1	-0.9	-1.1	0.2	1.5	-1.1	-0.1	-0.5	0.5
Neck or shoulder pain in last month	0.5	0.7	5.3	-0.8	-1.4	-0.8	-0.2	-2.3	0.7	-0.1	-0.4	-0.8	-0.2	-0.5	0.4	-0.2	-0.9	0.5	-1.1	0.9	-0.3	-0.6	-0.9	-0.8	-0.6	-0.5
Heart disease (mother)	0.5	0.6	2.7	0.7	1.1	0.7	0.1	-0.1	1.6	1.6	-0.2	0.1	0.5	0.8	1.3	0.2	-0.1	0.4	0.1	1.5	-0.3	-0.4	0.4	0.9	0.7	0.1
Number of full sisters	0.5	0.6	2.8	0.2	-1.2	0.2	0.4	1.1	1.7	1.1	0.3	-0.4	1.2	0.5	-1.2	1.0	0.7	0.9	0.2	-0.3	0.2	-0.8	0.5	0.0	0.4	0.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.9	0.1	0.8	0.1	-0.2	0.1	-1.3	-0.3	-0.0	0.5	-1.3	0.4	1.0	0.2	0.9	-1.2	0.5	0.1	0.9	1.4	1.2	0.2	0.3	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.5	-1.4	-0.3	-1.4	-0.0	-0.6	-0.6	-0.9	-0.3	-1.4	-0.1	-1.1	-0.4	-0.4	-1.2	-0.5	-1.4	-1.9	-1.3	-1.0	-0.7	-1.7	-1.5	-1.1
Eye problems/disorders: Cataract	0.5	0.6	2.2	-1.3	-0.2	-1.3	-1.5	0.3	-0.7	-0.4	-0.8	-0.6	-0.8	-0.2	0.1	-0.3	-0.5	-1.3	-0.3	-1.0	-0.3	-0.7	0.1	-1.1	-1.0	0.3
Breast cancer (self-reported)	0.5	0.6	2.3	-0.6	-0.8	-0.6	-1.0	0.4	-0.8	0.0	-0.1	-0.6	-1.4	-0.4	-0.3	-1.1	-0.6	-1.5	-0.8	-0.8	-0.9	-1.3	0.2	-0.6	-0.7	-0.5
Eye problems/disorders: Glaucoma	0.5	0.6	3.9	0.1	-0.1	0.1	0.1	-0.3	-1.4	-0.3	-2.0	0.1	0.5	-0.1	-1.4	-0.3	0.6	0.8	1.0	-0.8	-0.4	1.3	-0.2	-0.0	0.4	-0.9
Ever smoked	0.5	0.9	2.7	1.2	-0.4	1.2	0.4	1.1	0.0	1.6	1.0	1.0	-1.0	1.1	1.0	0.6	1.2	-0.8	0.1	-0.4	0.7	-0.3	1.6	1.1	1.3	1.1
Leg fat percentage (left)	0.5	1.6	9.7	1.1	1.0	1.1	0.4	-0.7	3.1	1.9	2.2	1.1	0.4	1.1	0.9	1.7	0.8	0.3	-0.4	0.3	1.2	-2.0	1.0	0.9	1.2	1.1
Irritability	0.5	0.9	4.1	-0.1	-0.1	-0.1	-1.0	0.8	-2.0	0.5	0.6	-0.5	-1.3	0.2	-0.5	-0.9	-0.6	-1.8	-2.0	-1.0	-1.2	0.1	-0.5	-0.2	-0.5	-0.9
Heart disease (siblings)	0.5	0.6	5.1	0.4	-1.3	0.4	0.2	-0.8	1.3	-0.4	-0.3	-0.6	0.7	-1.1	0.7	-0.3	-0.9	0.9	-0.5	2.2	-0.6	-0.4	-0.8	0.1	-0.1	-0.4
Intelligence (Savage-Jansen 2018)	0.4	1.3	4.5	0.7	-0.2	0.7	1.1	-0.1	-1.6	0.7	-2.1	0.9	1.0	0.8	-0.7	-0.3	1.9	0.4	1.9	-2.0	0.4	2.0	1.2	0.6	0.8	0.0
Alzheimer’s Disease (in mother)	0.4	0.5	3.3	-0.5	0.2	-0.5	-0.1	-0.2	-1.6	-1.2	-1.8	0.2	0.2	-1.4	0.1	0.2	-0.3	-0.2	0.7	-0.2	-0.7	0.2	0.6	-0.3	0.1	-0.7
Bipolar Disorder (2011)	0.4	0.4	3.6	-0.5	0.4	-0.5	-0.4	1.9	-1.4	-0.7	-0.5	-0.2	-0.1	-0.0	-0.1	-0.4	-0.4	-0.5	-0.5	-0.0	-0.5	0.9	-0.5	0.0	-0.4	-0.7
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.8	1.1	0.9	1.1	1.0	1.4	0.7	1.1	-0.4	0.2	1.0	0.6	1.1	1.1	0.8	0.7	0.0	0.7	0.4	0.8	-0.8	1.1	0.7	0.2
Lung FEV1/FVC ratio	0.4	1.9	9.4	0.9	0.9	0.9	1.1	-0.8	3.1	0.6	0.0	1.2	1.5	1.6	0.8	0.9	0.7	2.1	2.1	1.2	1.4	-2.5	1.0	1.1	1.5	0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	4.5	0.2	0.5	0.2	-0.2	-1.3	-0.0	0.8	0.2	0.3	-0.8	0.1	2.1	0.8	0.0	-0.1	-0.3	1.4	0.4	0.4	0.7	0.3	0.4	0.6
Medication for hormone replacement therapy	0.4	0.4	2.2	-0.9	-0.5	-0.9	-0.4	-0.1	-0.2	-1.5	0.0	-0.6	-0.9	-0.8	0.6	0.2	-0.9	-0.6	-0.2	0.2	-0.4	-1.0	-0.2	-0.7	-0.7	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	8.0	0.9	0.5	0.9	0.7	-0.2	1.2	0.6	0.1	1.0	0.3	0.6	2.8	0.6	0.3	0.8	1.3	1.2	0.6	-1.2	1.4	1.0	1.1	0.3
Multivitamins +/- minerals	0.4	0.5	3.3	-0.2	-0.2	-0.2	0.4	0.3	1.2	-0.2	-0.7	-0.2	1.8	-0.1	0.5	0.4	-0.6	1.8	0.9	1.0	0.1	-0.6	-0.5	-0.4	-0.2	-0.3
Chronic bronchitis/emphysema (father)	0.4	0.5	4.6	-0.2	-1.4	-0.2	-0.8	-0.8	0.0	0.2	0.3	-0.8	-2.1	-0.1	-0.6	-0.3	-0.2	-0.5	-0.8	-0.8	-0.2	-0.6	-0.6	-0.0	-0.6	0.2
Waist circumference	0.4	1.6	10.4	0.9	1.2	0.9	0.7	-0.2	3.2	1.8	2.3	0.8	1.3	1.4	0.4	1.9	0.8	0.6	-0.3	0.1	1.0	-2.0	0.9	0.5	0.8	0.9
Past tobacco smoking	0.4	0.8	4.1	-0.7	0.5	-0.7	0.5	-0.8	0.0	-0.9	-1.6	-0.4	2.0	-0.8	-0.5	-0.4	-0.6	1.6	0.9	0.8	-0.3	0.7	-1.1	-0.7	-0.7	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.8	0.0	-0.4	0.0	0.7	1.0	0.3	-0.2	-1.4	-0.9	1.9	0.1	-0.3	-0.5	-0.2	1.7	1.0	-0.2	-1.0	0.1	-0.9	0.0	-0.0	-1.4
Diabetes (self-reported)	0.4	0.5	1.6	1.0	0.7	1.0	0.4	1.3	0.6	1.3	0.8	0.3	0.3	1.0	0.3	1.2	0.8	-0.5	-0.6	0.3	0.1	0.0	0.2	1.0	0.9	0.3
Alcohol intake versus 10 years previously	0.4	0.6	2.2	0.6	-0.0	0.6	0.5	-1.1	0.8	1.4	0.9	0.7	0.2	0.8	0.1	1.0	0.4	0.8	0.9	0.7	1.5	0.8	0.0	0.4	0.3	1.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	5.5	-1.0	-0.3	-1.0	-0.2	-1.0	-2.2	-2.3	-1.0	-0.3	-0.2	-2.2	-1.2	-1.2	-0.6	-0.4	-0.1	-1.4	-1.0	0.6	-0.9	-0.9	-0.8	-1.5
Mouth/teeth dental problems: Dentures	0.4	0.7	2.2	1.2	0.7	1.2	0.0	-0.3	0.8	1.5	1.2	0.4	-0.8	0.3	1.0	0.6	0.4	-0.4	-0.4	1.4	0.5	0.6	0.4	1.2	0.8	1.1
Medication: Cholesterol lowering	0.4	0.6	2.5	0.5	1.1	0.5	0.5	0.3	0.3	0.5	1.4	1.0	-0.9	0.1	0.6	0.3	0.2	-1.6	-0.5	0.2	0.7	-0.8	0.7	1.1	0.8	1.0
Length of working week for main job	0.4	0.5	2.9	0.0	-0.8	0.0	-0.4	-0.1	0.9	0.4	1.7	-0.3	-0.3	0.7	-1.6	0.5	0.6	0.2	-0.1	-0.4	1.0	-0.2	-0.6	0.2	-0.3	1.0
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	2.5	0.0	-0.2	0.0	-0.1	-1.3	0.8	0.5	1.4	-0.4	-0.6	0.4	-1.6	1.3	1.1	-0.4	-0.5	-1.1	0.6	-0.1	-0.1	-0.0	-0.1	1.0
Glaucoma (self-reported)	0.4	0.5	4.1	0.4	-0.1	0.4	0.3	0.1	-0.4	0.2	-0.9	0.2	1.0	0.4	-2.0	0.8	0.9	1.4	0.9	-0.4	0.1	0.5	-0.4	0.2	0.6	-0.5
Birth weight	0.4	0.9	12.2	0.9	-0.0	0.9	0.9	0.6	0.1	-0.2	-1.2	0.3	-0.3	-0.4	3.5	-1.5	-0.3	0.3	0.8	0.2	-0.6	-0.4	-0.1	0.8	0.5	-0.7
Number of children fathered	0.4	0.5	1.4	1.2	0.5	1.2	0.7	-0.8	0.7	0.4	1.1	0.8	-0.5	0.4	-0.1	0.2	-0.0	0.0	0.4	0.9	0.4	-0.5	0.7	1.2	0.7	0.5
Migraine (self-reported)	0.4	0.5	2.3	-0.3	0.6	-0.3	-0.3	-1.4	-0.8	0.1	-0.5	0.5	-0.6	0.5	-0.4	0.3	1.2	-1.0	-0.1	-1.5	0.8	0.9	0.5	0.1	0.2	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	3.1	-0.4	-0.2	-0.4	-0.5	-1.8	1.0	0.2	0.8	-0.1	-0.7	0.5	-0.7	1.2	0.3	-0.3	-0.6	-0.1	0.5	-1.1	-0.1	-0.5	-0.1	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	2.2	0.2	0.9	0.2	0.9	-1.3	-0.4	0.2	-0.5	0.3	0.4	-0.8	-0.1	0.4	1.3	0.3	0.5	-1.5	0.5	0.5	0.1	0.4	0.3	0.2
Illnesses of father: Heart disease	0.4	0.5	1.3	0.6	1.2	0.6	0.7	-0.1	0.7	1.0	1.1	0.8	0.3	0.6	1.1	0.9	0.6	-0.2	0.0	0.5	0.7	0.2	0.8	0.7	0.7	0.9
Osteoporosis (self-reported)	0.4	0.5	2.7	-0.8	-0.7	-0.8	-0.9	0.1	0.2	-1.6	-0.2	-0.4	0.1	0.1	0.3	-0.9	-1.1	0.5	0.0	1.1	-0.1	-0.8	-0.2	-0.8	-0.6	0.0
Ever taken oral contraceptive pill	0.4	0.5	2.6	-0.1	0.7	-0.1	0.7	-1.4	1.0	-0.6	-0.7	-0.0	0.7	-0.6	0.9	-0.4	-0.7	0.8	0.6	0.6	-0.3	-1.6	0.0	-0.1	0.2	-0.3
Medication: Paracetamol	0.4	0.7	4.0	-0.0	0.4	-0.0	0.7	-1.6	0.6	0.3	-0.9	0.8	2.0	0.3	-0.7	0.4	1.0	1.4	1.4	-0.3	0.5	-0.1	0.7	-0.1	0.6	-0.3
Myopia	0.4	0.6	3.5	0.2	-0.2	0.2	0.6	-0.7	1.9	0.8	0.0	0.1	0.9	0.7	1.3	0.2	-0.6	1.3	0.6	1.8	-0.1	-1.2	-0.0	0.1	0.2	-0.3
Basal cell carcinoma (self-reported)	0.4	0.5	2.9	-0.3	0.8	-0.3	0.1	1.7	0.0	0.5	0.3	0.5	1.0	1.5	0.5	0.4	0.0	0.2	0.1	1.3	0.6	1.0	0.8	-0.3	0.0	0.5
Body Mass Index (BMI) (2010)	0.3	0.5	2.0	-0.7	0.3	-0.7	-0.3	0.7	1.4	1.0	1.1	0.2	0.8	0.6	-0.0	0.9	-0.1	0.7	-0.3	0.7	1.0	-0.2	-0.3	-0.7	-0.5	0.5
Crohns Disease (2012)	0.3	0.6	3.3	0.3	0.7	0.3	0.9	-0.7	1.4	-0.0	-0.4	0.5	0.9	0.0	1.8	0.3	0.2	1.4	0.7	0.8	0.6	-0.6	0.6	0.2	0.5	-0.1
HDL Cholesterol	0.3	0.4	1.7	-0.2	-1.0	-0.2	-0.3	0.7	-0.5	-1.0	-0.1	-0.7	-0.1	-1.0	0.1	-1.1	-0.6	-0.8	-0.2	-0.6	-1.3	-0.9	0.1	-0.4	-0.5	-0.8
LDL Cholesterol	0.3	0.5	3.7	-0.2	-0.8	-0.2	-0.2	-0.4	-0.2	1.2	0.1	-0.6	0.2	0.5	-1.9	-0.7	-0.2	0.0	-0.7	-0.5	-0.2	0.6	-1.6	-0.2	-0.6	-0.4
Lupus	0.3	0.5	2.0	0.8	-0.2	0.8	0.9	1.2	0.6	0.7	-0.2	-0.4	0.4	1.0	1.4	-0.2	0.4	0.3	0.6	1.0	-0.2	0.6	0.2	1.0	0.6	0.4
Triglycerides	0.3	0.5	2.8	-0.6	0.4	-0.6	-0.7	1.2	0.7	0.1	0.4	0.6	-0.1	1.2	-1.7	0.7	-0.5	-0.2	-0.2	0.2	0.8	-1.1	-0.2	-0.3	-0.1	0.6
Blood Platelet Count	0.3	3.7	15.2	1.3	1.2	1.3	0.3	-0.4	3.3	1.0	3.9	0.7	0.8	2.3	-0.8	3.6	1.5	1.5	0.6	3.0	2.6	0.2	0.6	1.4	1.1	3.4
Blood Red Count	0.3	2.6	21.2	1.0	1.3	1.0	2.4	-0.3	1.3	2.0	0.6	1.4	0.8	0.4	4.6	1.9	1.6	1.1	1.4	0.6	2.1	1.1	1.4	1.0	1.2	1.8
BMI	0.3	1.5	14.4	0.3	-0.5	0.3	0.2	-1.2	3.8	1.2	2.3	-0.7	0.5	0.6	0.8	1.4	0.0	1.0	-1.1	0.7	0.3	-2.6	-0.6	0.2	-0.1	0.3
Smoking Status	0.3	0.8	3.7	0.4	-0.8	0.4	-0.9	1.9	0.4	0.7	1.6	-0.1	-1.8	0.8	0.5	0.4	0.2	-1.5	-1.5	-0.2	0.5	-0.6	0.2	0.3	0.1	1.3
Average weekly spirits intake	0.3	0.3	2.4	0.4	0.2	0.4	-0.0	1.5	0.3	-0.1	-0.1	-0.1	0.0	-1.1	0.3	-0.3	-0.6	0.1	0.3	1.5	-0.4	-0.4	-0.3	0.7	0.4	-0.2
Trunk fat percentage	0.3	1.0	7.1	0.4	0.6	0.4	-0.2	-0.7	2.7	1.1	2.3	0.4	-0.1	0.3	0.5	0.9	-0.3	-0.1	-1.4	0.3	0.3	-2.5	0.5	0.3	0.4	0.3
Current tobacco smoking	0.3	0.4	1.7	0.3	-0.5	0.3	0.2	1.1	1.1	1.0	0.5	-0.3	1.0	1.0	0.3	1.3	0.8	1.0	0.1	0.6	0.4	-0.1	0.3	0.2	0.3	0.4
Relative age voice broke	0.3	0.4	1.8	0.5	0.4	0.5	0.2	-0.4	-1.2	-0.2	0.2	0.8	-1.2	-0.4	0.4	-0.0	0.4	-1.2	-0.2	-1.3	-0.2	-0.3	0.5	0.6	0.5	-0.1
High blood pressure (mother)	0.3	0.5	2.1	1.0	-1.4	1.0	0.1	-0.5	1.2	-0.0	1.5	-0.2	-0.4	0.1	-0.2	0.6	0.7	0.3	-0.1	-0.0	0.3	-0.5	-0.3	0.9	0.4	0.7
Body mass index (BMI)	0.3	1.1	10.6	0.4	-0.0	0.4	0.2	-1.1	3.3	1.3	2.0	-0.2	0.9	0.4	-0.1	1.2	0.2	0.8	-0.8	-0.1	0.4	-2.1	-0.2	0.1	0.1	0.1
Impedance of leg (left)	0.3	1.5	3.5	1.1	1.7	1.1	1.0	1.7	-0.5	0.1	0.4	1.8	-0.1	1.2	1.8	1.5	1.0	-0.4	0.7	1.3	1.1	0.7	1.9	1.5	1.8	1.3
Allergy	0.3	0.6	3.9	0.5	-0.1	0.5	0.6	-0.8	2.0	0.8	-0.2	-0.2	0.5	0.6	1.7	-0.3	-0.3	1.5	0.3	0.9	0.3	-0.8	-1.1	0.3	-0.1	-0.3
Arm fat percentage (right)	0.3	1.1	8.0	0.3	0.3	0.3	-0.3	-0.8	2.8	1.3	2.4	0.2	0.1	0.4	0.1	1.2	0.2	-0.2	-1.4	-0.2	0.7	-2.1	0.4	0.1	0.2	0.6
Hip circumference	0.3	1.5	5.9	-0.4	-0.5	-0.4	-0.9	-1.3	2.3	0.5	2.0	-1.1	0.5	-0.1	-1.7	-0.1	-1.1	-0.0	-2.2	-0.9	-1.2	-2.4	-1.2	-0.7	-1.0	-1.4
Father’s age at death	0.3	0.4	1.8	0.8	0.8	0.8	0.7	0.6	-0.3	-0.3	-0.5	1.0	-0.1	-1.1	1.3	0.1	0.2	0.4	0.6	0.1	0.0	-0.5	0.9	0.7	1.0	-0.2
Worrier / anxious feelings	0.3	0.6	2.8	0.3	-1.5	0.3	0.4	0.2	-1.3	-0.4	-0.9	-0.5	-0.2	-0.3	-0.6	-1.7	-0.5	-0.6	-0.4	-0.2	-1.6	0.6	-0.6	0.4	0.0	-1.4
Hair/balding pattern: Pattern 3	0.3	0.4	2.5	0.2	-0.3	0.2	-0.3	-0.8	-0.3	-0.5	0.1	-0.4	-1.2	-1.6	-0.7	-0.5	-0.2	-1.4	-0.7	-0.3	-0.3	0.4	-0.0	0.2	-0.4	0.5
Number of live births	0.3	0.5	3.1	0.5	-1.4	0.5	0.6	0.8	0.8	-0.4	0.3	-0.5	0.5	-0.3	-1.8	1.0	0.9	0.3	-0.6	-0.7	-0.3	0.8	-0.4	0.3	0.2	0.1
Illnesses of mother	0.3	0.3	0.8	-0.1	0.3	-0.1	0.8	0.6	-0.4	0.1	0.4	0.5	0.8	0.9	-0.9	0.6	0.5	0.0	0.7	-0.9	0.9	-0.3	0.6	-0.2	0.2	0.6
Peak expiratory flow (PEF)	0.3	0.6	2.6	0.5	0.4	0.5	1.3	0.2	-0.1	-0.5	0.1	0.8	0.8	0.5	-0.7	1.5	1.6	1.0	0.9	-1.3	0.9	0.6	0.6	0.4	0.8	0.3
Body fat percentage	0.3	1.3	9.0	0.6	0.7	0.6	0.0	-0.8	3.0	1.5	2.5	0.6	0.2	0.7	0.6	1.3	0.1	0.1	-1.1	0.4	0.6	-2.3	0.6	0.5	0.6	0.6
Leg fat percentage (right)	0.3	1.2	7.0	0.7	0.9	0.7	0.0	-0.6	2.6	1.6	2.0	1.0	0.0	1.2	0.7	1.4	0.6	-0.1	-0.8	-0.1	1.0	-2.0	0.9	0.6	0.9	0.9
Medication: Omeprazole	0.3	0.3	1.5	-0.4	-0.1	-0.4	-1.0	0.3	0.1	-0.0	0.9	-0.2	-0.3	0.8	0.6	0.1	-0.7	-0.8	-1.2	-0.1	-0.2	-0.9	-0.3	-0.3	-0.4	-0.1
Leg fat mass (right)	0.3	1.0	8.2	0.3	0.6	0.3	-0.0	-0.7	2.9	1.4	2.0	0.3	0.8	0.8	-0.0	1.2	0.1	0.4	-0.9	-0.4	0.4	-2.3	0.3	0.0	0.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	3.1	0.5	-0.8	0.5	0.0	-1.1	-0.6	-0.4	0.2	0.0	0.0	-0.1	-1.8	0.4	0.1	0.2	-0.2	0.3	0.1	1.0	-0.7	0.5	0.0	-0.1
Arm fat percentage (left)	0.3	1.0	8.8	0.1	-0.2	0.1	-0.5	-1.1	3.0	1.1	2.2	-0.3	0.2	0.2	-0.1	0.6	-0.3	0.0	-1.5	-0.1	0.2	-2.3	-0.3	-0.2	-0.2	0.1
Diabetes diagnosed by doctor	0.3	0.5	2.1	0.9	0.9	0.9	0.7	0.9	0.7	0.9	0.7	0.5	0.4	1.0	0.9	1.4	0.8	-0.3	-0.3	0.4	0.4	0.1	0.1	1.0	0.9	0.5
Friendships satisfaction	0.3	0.4	1.5	1.0	0.3	1.0	0.7	0.2	-0.4	-0.0	-0.5	-0.4	0.2	-0.7	-1.1	-0.1	0.9	0.5	0.2	-1.2	-0.7	0.6	-0.3	0.6	0.2	-0.7
Back pain experienced in last month	0.3	0.4	1.6	-0.6	-1.3	-0.6	0.4	-0.1	1.3	-0.5	0.4	-0.5	1.1	0.7	0.0	0.6	0.1	0.6	-0.1	-0.4	-0.2	-0.9	-0.7	-0.4	-0.3	-0.3
Smoking status: Current	0.3	0.4	1.2	0.3	-0.2	0.3	0.2	1.1	1.0	0.8	0.6	-0.2	0.8	1.1	0.7	1.0	0.5	0.8	0.0	1.0	0.3	-0.3	0.3	0.2	0.4	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.3	-0.9	-0.7	-0.9	-0.3	-1.8	-1.0	-1.2	-0.8	-0.3	0.6	-1.5	-0.5	-0.2	-0.3	0.9	0.7	0.3	0.4	1.0	-0.6	-0.8	-0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.6	-0.3	0.6	-0.3	0.2	-1.1	0.0	-0.4	0.2	0.2	1.2	-0.9	-0.1	-0.9	-0.7	0.6	0.7	0.8	0.1	0.0	0.0	-0.1	-0.2	-0.3
High cholesterol (Self-reported)	0.3	0.5	2.0	1.0	0.8	1.0	1.4	-0.9	1.2	0.7	0.4	0.6	0.2	0.1	-0.0	0.6	0.7	0.2	0.1	-0.1	0.7	-0.6	-0.1	0.9	0.7	0.6
Average weekly beer plus cider intake	0.3	0.5	3.1	0.4	0.4	0.4	-0.3	0.3	0.7	0.3	1.1	0.5	0.0	0.6	-0.3	1.8	1.0	0.1	-0.0	0.4	1.2	0.7	0.3	0.4	0.6	1.3
Cholesterol lowering medication	0.3	0.4	1.3	1.2	0.5	1.2	0.9	-0.2	0.1	1.0	-0.5	0.8	-0.4	-0.4	-0.4	-0.2	0.8	-0.3	-0.0	-0.3	0.5	0.7	0.1	1.1	0.8	0.5
Leg fat mass (left)	0.3	1.1	8.8	0.4	0.6	0.4	0.1	-0.8	3.0	1.5	2.1	0.3	0.9	0.6	-0.0	1.3	0.2	0.4	-0.8	-0.3	0.4	-2.2	0.4	0.2	0.4	0.3
Depressed Affect (Nagel 2018)	0.2	0.4	1.8	0.6	-0.3	0.6	0.0	1.1	0.5	0.6	0.5	-1.0	0.4	0.9	-0.2	0.4	0.3	0.4	-0.7	0.2	-0.3	1.1	-1.4	0.6	-0.2	-0.1
Major Depression (MDD)	0.2	0.2	0.7	-0.6	-0.2	-0.6	-0.2	0.0	-0.7	0.7	0.4	-0.0	-0.4	0.2	-0.8	0.1	-0.4	-0.3	-0.3	0.1	0.5	0.4	-0.0	-0.6	-0.5	0.7
Fasting Glucose	0.2	0.2	2.9	0.2	-0.2	0.2	-0.1	-1.7	-0.1	0.7	-0.4	-0.1	-0.1	0.3	-0.8	0.0	0.1	0.3	0.3	0.0	0.2	0.7	-0.2	0.1	-0.1	0.3
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.1	-1.0	-0.1	-1.0	-0.4	-1.0	0.0	-0.4	0.2	0.1	1.0	-0.5	-0.8	-0.4	-0.2	0.1	0.1	-0.1	0.1	-0.5	-0.1	-0.6	-0.3	-0.4
Height	0.2	4.0	13.9	-1.7	-1.6	-1.7	-2.0	-0.9	-3.7	-2.0	-1.4	-1.5	-2.2	-1.8	-2.8	-2.3	-1.5	-2.8	-2.1	-3.0	-2.5	-0.1	-0.5	-1.6	-1.6	-2.0
Respiratory disease	0.2	0.5	4.2	0.3	1.3	0.3	-0.0	2.0	-1.1	0.1	-0.2	0.6	-0.0	-0.8	-0.8	-0.2	0.3	-0.5	0.4	-0.6	-0.2	0.1	1.2	0.3	0.5	-0.2
Tanning	0.2	2.2	4.9	1.3	1.9	1.3	1.4	1.6	1.5	1.5	2.1	1.9	0.3	1.6	1.6	1.9	1.5	0.1	0.8	0.8	1.8	-0.3	2.2	1.3	1.6	2.0
Medication: Metformin	0.2	0.3	1.3	0.5	0.5	0.5	0.9	0.7	-0.3	0.4	-1.0	0.2	1.0	-0.0	0.5	0.4	0.5	0.1	0.3	0.3	-0.3	1.2	-0.2	0.7	0.5	-0.3
Impedance of leg (right)	0.2	1.2	3.2	0.8	1.5	0.8	0.5	1.8	-1.1	-0.2	0.1	1.8	-0.7	1.3	1.4	1.0	0.9	-0.9	0.4	0.5	0.9	0.7	1.7	1.2	1.5	1.2
Leg fat-free mass (left)	0.2	1.0	3.8	-0.8	-0.4	-0.8	-0.6	-0.8	0.9	0.1	0.7	-1.2	0.6	-0.5	-1.9	-0.5	-0.8	0.2	-1.1	-1.7	-1.3	-1.6	-1.0	-1.1	-1.1	-1.3
Townsend deprivation index at recruitment	0.2	0.3	1.8	-0.8	-0.8	-0.8	-0.5	0.3	0.5	0.3	0.4	-1.1	0.1	0.1	0.3	1.3	0.0	0.0	-0.3	-0.1	0.1	0.1	-0.4	-0.6	-0.7	0.7
Fed-up feelings	0.2	0.4	1.7	-0.0	-0.2	-0.0	-0.2	1.0	0.3	0.4	0.1	-1.0	0.8	1.0	-0.6	0.1	0.2	0.3	-0.9	-1.1	-0.9	0.3	-1.3	-0.2	-0.4	-1.0
Age when periods started (menarche)	0.2	0.6	1.4	0.7	0.5	0.7	-0.3	0.6	-1.0	-0.7	0.4	0.9	-1.1	0.6	-0.6	0.8	0.7	-1.2	0.0	0.0	0.7	0.7	1.1	0.8	0.9	1.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	2.2	0.3	-0.1	0.3	-0.1	-1.5	0.8	1.2	0.5	-0.2	-0.3	-0.2	-0.2	0.6	-0.0	0.4	-0.1	-0.1	0.2	0.2	-0.7	0.2	-0.3	-0.1
Sitting height	0.2	1.3	4.9	-0.7	0.3	-0.7	-0.8	-0.8	-1.4	-0.1	-0.2	-0.6	-0.2	-0.9	-1.6	-2.2	-2.2	-1.2	-1.5	0.1	-2.2	-0.4	-0.9	-0.8	-0.9	-1.9
Leg predicted mass (left)	0.2	1.0	3.9	-0.8	-0.4	-0.8	-0.5	-0.8	0.9	0.1	0.7	-1.1	0.6	-0.4	-2.0	-0.5	-0.7	0.2	-1.1	-1.7	-1.2	-1.6	-1.0	-1.1	-1.1	-1.2
Trunk fat mass	0.2	0.9	6.7	0.1	0.3	0.1	-0.3	-0.9	2.6	1.0	2.1	0.0	0.2	0.2	-0.0	0.6	-0.5	-0.0	-1.4	-0.1	-0.1	-2.5	0.1	0.0	0.1	-0.2
Hearing difficulty/problems with background noise	0.2	0.3	2.7	-0.1	-0.5	-0.1	0.4	1.6	0.2	0.4	-0.9	0.5	-0.1	-0.0	0.5	-1.1	-0.3	0.5	0.7	-0.4	0.4	-0.6	0.1	0.1	0.1	-0.1
Weight	0.2	0.9	6.2	-0.2	-0.1	-0.2	-0.3	-0.8	1.9	0.7	1.5	-0.5	0.5	-0.1	-1.0	0.0	-0.7	-0.1	-1.4	-1.1	-0.8	-2.5	-0.5	-0.5	-0.4	-1.0
Trunk fat-free mass	0.2	0.9	3.2	-0.7	-0.4	-0.7	-0.3	-0.1	0.0	-0.5	-0.4	-1.0	0.6	-0.8	-1.8	-1.0	-1.0	0.1	-0.5	-1.4	-1.7	-1.2	-0.9	-0.9	-0.8	-1.8
Pulse rate	0.2	0.3	1.5	-0.0	-0.0	-0.0	0.3	1.0	0.9	-0.4	-0.3	-0.0	0.9	-0.1	-1.0	0.5	0.3	1.2	0.4	-0.8	-0.0	-0.3	-0.4	-0.2	-0.1	-0.4
Noisy workplace	0.2	0.2	1.4	-0.3	-0.5	-0.3	-0.3	-0.0	-1.2	-0.0	-0.0	0.4	-0.9	0.5	-0.4	-0.3	-0.2	-0.9	-0.5	0.2	0.5	0.0	0.4	-0.2	0.1	0.4
Arm fat mass (right)	0.2	0.9	7.6	0.2	0.1	0.2	-0.1	-0.9	2.8	1.0	2.0	-0.2	0.7	0.1	-0.2	0.8	-0.2	0.3	-1.2	-0.4	-0.0	-2.3	-0.1	-0.1	-0.1	-0.1
Standing height	0.2	2.3	7.6	-1.3	-0.4	-1.3	-0.9	0.5	-2.2	-1.4	-0.9	-1.0	-0.5	-1.4	-1.9	-2.3	-2.1	-1.4	-1.4	-2.1	-2.8	-1.3	-0.8	-1.2	-1.3	-2.5
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.0	0.3	0.1	0.3	0.3	0.3	0.6	0.9	1.0	-0.0	0.4	0.6	-0.9	0.7	0.2	-0.1	0.3	-0.1	-0.2	-0.9	0.9	0.3	0.4	0.3
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.8	-0.2	0.5	-0.2	-0.2	0.2	0.3	-0.1	-0.1	-0.5	-0.2	-1.3	1.1	-0.3	-0.4	0.3	-0.6	0.6	-0.2	0.6	-0.7	-0.4	-0.3	-0.1
Arm fat-free mass (right)	0.2	0.9	3.0	-0.8	-0.5	-0.8	-0.2	-0.5	1.0	-0.3	0.2	-1.1	1.0	-0.6	-1.1	-0.5	-1.1	0.9	-0.6	-0.8	-1.4	-1.7	-1.2	-0.9	-0.9	-1.7
Exposure to tobacco smoke outside home	0.2	0.3	1.7	-0.4	-0.0	-0.4	-0.3	0.8	0.4	-0.7	0.8	-0.5	0.3	-0.7	0.5	1.3	-0.1	0.2	0.0	1.3	0.1	-0.4	0.7	-0.3	0.0	0.5
Comparative body size at age 10	0.2	0.6	2.7	0.7	0.2	0.7	0.8	-0.6	1.6	1.4	1.0	0.3	0.3	0.9	0.7	1.2	0.9	0.7	0.2	-0.9	0.3	-1.1	0.1	0.4	0.5	-0.1
Whole body fat mass	0.2	1.0	7.7	0.2	0.3	0.2	-0.1	-0.8	2.8	1.1	2.2	-0.1	0.7	0.3	-0.1	1.0	-0.3	0.3	-1.2	0.0	-0.0	-2.2	0.0	0.0	0.1	-0.0
Arm predicted mass (right)	0.2	1.0	3.2	-0.9	-0.4	-0.9	-0.2	-0.6	1.1	-0.5	0.2	-1.1	1.4	-0.8	-1.3	-0.5	-1.3	1.1	-0.5	-0.8	-1.4	-1.7	-1.3	-1.1	-1.0	-1.8
Alcohol intake frequency.	0.2	0.5	3.0	-0.4	-0.1	-0.4	0.1	-0.7	0.6	-0.2	1.7	0.7	-0.5	0.1	0.6	1.4	0.0	0.1	-0.7	0.5	1.5	-0.9	-0.0	-0.8	-0.0	1.0
Knee pain experienced in last month	0.2	0.3	1.7	0.3	0.4	0.3	0.8	-0.3	0.2	0.5	-0.3	0.1	1.3	0.2	-0.7	0.3	0.6	1.1	0.0	-0.8	-0.1	0.7	-0.2	0.0	0.3	-0.7
Whole body fat-free mass	0.2	0.9	3.6	-0.8	-0.4	-0.8	-0.4	-0.4	0.4	-0.2	0.1	-1.1	0.7	-0.7	-1.9	-0.7	-0.9	0.2	-0.7	-1.5	-1.6	-1.5	-0.9	-1.0	-0.9	-1.6
Leg fat-free mass (right)	0.2	1.0	3.3	-0.8	-0.5	-0.8	-0.4	-0.9	1.1	0.2	0.8	-1.3	0.9	-0.5	-1.8	-0.4	-0.9	0.5	-1.0	-1.2	-1.3	-1.5	-1.2	-1.1	-1.2	-1.3
Loneliness, isolation	0.2	0.2	1.0	0.9	-0.4	0.9	0.6	0.3	0.7	0.5	0.4	-0.2	0.1	0.2	0.8	-0.1	0.3	0.2	-0.1	0.1	-0.3	-0.3	-0.0	1.0	0.5	0.1
Whole body water mass	0.2	1.2	3.9	-1.0	-0.6	-1.0	-0.5	-0.7	0.4	-0.5	0.0	-1.2	0.7	-0.8	-2.0	-0.9	-1.2	0.2	-0.9	-1.6	-1.7	-1.6	-1.1	-1.2	-1.1	-1.8
Leg predicted mass (right)	0.2	1.0	3.5	-0.8	-0.4	-0.8	-0.4	-0.9	1.1	0.1	0.7	-1.3	1.0	-0.6	-1.9	-0.4	-1.0	0.5	-1.0	-1.2	-1.3	-1.5	-1.2	-1.1	-1.2	-1.4
Arm fat mass (left)	0.2	1.0	8.8	0.0	-0.1	0.0	-0.2	-1.0	3.0	0.9	1.8	-0.4	0.8	-0.0	-0.3	0.6	-0.3	0.6	-1.0	-0.3	-0.1	-2.4	-0.3	-0.2	-0.2	-0.2
Average weekly champagne plus white wine intake	0.2	0.3	1.5	0.4	-0.0	0.4	0.6	1.2	0.6	-0.3	0.3	-0.1	0.2	0.6	-0.4	-0.1	0.1	0.2	0.2	-0.8	-1.0	-1.0	0.1	0.5	0.3	-0.8
Wears glasses or contact lenses	0.2	0.2	0.6	-0.2	-0.1	-0.2	-0.6	-0.7	0.8	0.5	-0.3	-0.4	0.2	0.2	-0.6	0.4	-0.5	0.3	-0.3	0.3	-0.1	-0.2	-0.5	-0.4	-0.4	-0.4
Basal metabolic rate	0.2	0.9	2.9	-0.7	-0.4	-0.7	-0.3	-0.6	0.9	0.0	0.5	-1.1	0.9	-0.5	-1.7	-0.5	-0.9	0.4	-0.8	-1.4	-1.4	-1.7	-0.9	-0.9	-0.9	-1.5
Risk taking	0.2	0.3	1.1	0.8	-0.4	0.8	0.8	0.4	0.6	-0.1	0.6	0.3	1.1	0.6	0.2	0.6	0.4	0.6	0.8	0.5	0.2	-0.1	0.9	0.6	0.6	0.4
Fractured/broken bones in last 5 years	0.2	0.3	1.0	0.1	-0.4	0.1	-0.2	0.4	0.1	0.5	0.1	-0.8	-1.0	0.9	0.2	0.2	0.2	-0.9	-0.8	-0.9	-0.7	-0.7	-0.1	0.3	-0.1	-0.1
Pain experienced in last month	0.2	0.4	1.7	0.4	0.7	0.4	-0.6	-0.1	-0.6	0.1	0.2	0.5	-1.3	-1.2	1.1	-0.6	-0.4	-1.3	-0.2	0.6	-0.1	-0.4	0.8	0.5	0.3	0.3
Blood Eosinophil Count	0.1	0.5	2.8	-0.0	-0.4	-0.0	-0.4	1.1	1.4	-0.3	1.7	-0.5	0.2	0.2	-0.1	0.4	-1.0	-0.3	-1.0	1.6	-0.2	-1.1	-0.4	-0.1	-0.3	0.2
Hair Pigment	0.1	2.4	8.5	-2.7	-2.1	-2.7	-1.6	-1.9	0.6	-1.8	-0.8	-2.3	0.4	-0.7	-0.3	1.0	-1.2	0.7	-1.5	-0.1	-0.6	-0.7	-1.5	-2.9	-2.4	-0.5
Medication: Simvastatin	0.1	0.1	0.6	0.3	-0.1	0.3	0.1	-0.1	0.5	0.2	-0.4	-0.2	-0.4	-0.1	-0.8	0.2	0.2	-0.4	-0.3	0.6	0.4	0.1	-0.3	0.6	0.1	0.5
Impedance of arm (right)	0.1	0.5	3.1	-0.0	0.4	-0.0	-0.6	1.1	-1.4	-0.2	0.4	0.7	-1.4	0.5	-0.4	0.2	0.2	-1.8	-0.8	-0.2	0.2	0.3	1.3	0.1	0.3	0.9
Impedance of arm (left)	0.1	0.5	2.4	-0.2	-0.0	-0.2	-0.8	0.7	-1.4	-0.7	0.0	-0.1	-1.4	-0.2	-0.2	-0.8	-0.7	-1.5	-1.1	0.2	-0.6	0.1	0.2	-0.0	-0.2	0.0
Trunk predicted mass	0.1	0.8	3.1	-0.6	-0.4	-0.6	-0.2	-0.0	0.1	-0.4	-0.3	-0.9	0.7	-0.7	-1.8	-1.0	-1.0	0.2	-0.5	-1.3	-1.7	-1.2	-0.8	-0.8	-0.7	-1.7
Hair/balding pattern: Pattern 4	0.1	0.3	1.7	0.5	0.8	0.5	0.4	-0.9	0.7	0.5	-0.4	0.7	-0.5	-0.7	1.3	-1.2	-0.0	0.3	0.2	0.1	0.3	-0.4	-0.3	0.5	0.3	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.6	-0.3	0.2	-0.3	-0.9	-1.3	-0.6	-0.6	0.3	-0.0	-0.6	-0.5	-0.0	0.1	-0.5	0.1	-0.1	0.2	0.2	-0.6	-0.5	-0.3	-0.3	-0.3
Comparative height size at age 10	0.1	0.6	2.2	-0.3	-0.0	-0.3	-0.2	-0.2	-0.6	0.2	-0.1	-0.8	0.1	-0.9	-0.0	-1.4	-1.5	-0.8	-1.2	-0.2	-1.5	-0.1	-0.9	-0.3	-0.9	-1.1
Had major operations	0.1	0.1	0.7	0.3	-0.6	0.3	-0.2	-0.2	0.2	-0.0	-0.0	0.0	-0.6	0.5	0.4	-0.2	-0.5	-0.0	-0.1	0.9	-0.0	0.6	-0.1	0.4	-0.2	0.4
Arm fat-free mass (left)	0.1	0.5	2.5	-0.4	0.0	-0.4	0.0	-0.3	0.9	0.1	0.3	-0.6	1.1	-0.5	-1.2	-0.2	-0.5	0.5	-0.4	-1.3	-1.1	-1.6	-0.4	-0.6	-0.4	-1.3
Impedance of whole body	0.1	0.7	1.9	0.6	0.9	0.6	0.2	1.3	-0.8	-0.1	0.7	1.2	-1.0	0.9	1.0	0.5	0.3	-1.1	-0.2	0.9	0.7	0.4	1.4	1.0	1.0	1.2
Arm predicted mass (left)	0.1	0.6	2.0	-0.6	-0.0	-0.6	-0.0	-0.3	0.8	-0.1	0.4	-0.7	1.2	-0.5	-1.2	-0.2	-0.6	0.6	-0.5	-1.3	-1.0	-1.4	-0.6	-0.8	-0.6	-1.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

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Trait associations