[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr15:50,147,368-51,678,028

Best TWAS P=1.57e-13 · Best GWAS P=4.29e-14 conditioned to 0.0349

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere TRPM7 0.28 0.06 enet 17 0.03 7.0e-02 7.4 6.5 5.7e-11 0.92 0.02 0.91 FALSE
2 GTEx Brain Cerebellum TRPM7 0.17 0.14 lasso 3 0.13 1.3e-04 7.3 7.1 9.8e-13 0.91 0.02 0.94 FALSE
3 GTEx Muscle Skeletal TRPM7 0.08 0.05 lasso 7 0.07 4.4e-07 7.3 6.3 3.0e-10 0.82 0.03 0.97 FALSE
4 The Cancer Genome Atlas Esophageal Carcinoma TRPM7 0.19 0.02 enet 14 0.06 7.3e-03 -7.1 -5.8 6.4e-09 -0.62 0.07 0.45 FALSE
5 The Cancer Genome Atlas Glioblastoma Multiforme USP8 0.31 0.20 blup 58 0.21 5.5e-07 -6.0 6.0 2.2e-09 0.67 0.10 0.78 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma USP8 0.05 0.01 blup 59 0.02 1.8e-03 -3.5 6.0 2.3e-09 0.65 0.02 0.80 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma USP8 0.07 0.05 lasso 3 0.06 4.2e-04 -4.1 5.9 4.3e-09 0.54 0.14 0.42 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma TRPM7 0.03 0.04 lasso 1 0.03 9.2e-05 -7.1 -7.1 1.7e-12 -0.82 0.10 0.86 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma USP8 0.03 0.01 lasso 4 0.01 3.2e-02 -6.3 6.2 7.8e-10 0.60 0.06 0.17 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma USP8 0.02 0.02 enet 4 0.02 9.9e-04 -6.8 7.2 4.1e-13 0.83 0.01 0.95 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma USP8 0.07 0.03 lasso 5 0.01 1.5e-01 7.3 7.3 2.0e-13 0.88 0.01 0.76 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma TRPM7 0.03 0.03 lasso 2 0.03 3.4e-04 7.4 -7.4 1.6e-13 -0.90 0.02 0.96 TRUE