Hub : Genes

USP8

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0720	0.0330	3.5e-03	0.004	0.021	0.021	0.024	-0.001	9.5e-02	1.2e-03	1.1e-03	5.0e-04	5.6e-01
2	GTEx	Artery Tibial	0.1397	0.0478	4.2e-04	0.062	NA	0.101	NA	0.114	1.3e-05	NA	2.7e-08	NA	3.2e-09
3	GTEx	Breast Mammary Tissue	0.1470	0.0570	2.8e-03	0.049	NA	0.041	NA	0.091	1.5e-03	NA	3.6e-03	NA	2.2e-05
4	GTEx	Breast Mammary Tissue (Male)	0.0482	0.0686	2.8e-01	-0.011	NA	-0.009	NA	-0.009	7.0e-01	NA	5.6e-01	NA	5.9e-01
5	GTEx	Esophagus Muscularis	0.1350	0.0490	4.1e-04	0.004	NA	0.075	NA	0.046	1.6e-01	NA	2.5e-05	NA	9.1e-04
6	GTEx	Testis	0.1570	0.0660	5.0e-03	0.120	NA	0.090	NA	0.100	5.8e-06	NA	8.1e-05	NA	3.4e-05
7	NTR	Blood	0.0141	0.0068	1.0e-02	0.002	0.004	0.002	0.005	0.002	7.4e-02	1.2e-02	8.6e-02	6.9e-03	6.4e-02
8	YFS	Blood	0.0190	0.0081	3.8e-05	0.005	0.013	0.010	0.013	0.006	6.2e-03	2.4e-05	2.3e-04	2.8e-05	2.8e-03
9	TCGA	Glioblastoma Multiforme	0.3050	0.1000	2.9e-06	0.197	0.209	0.192	NA	0.170	1.3e-06	5.5e-07	1.8e-06	NA	7.2e-06
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0461	0.0270	1.1e-03	0.009	0.021	0.008	NA	0.016	3.2e-02	1.8e-03	4.2e-02	NA	5.1e-03
11	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0750	0.0370	1.0e-03	0.045	0.049	0.048	NA	0.055	1.3e-03	8.3e-04	9.8e-04	NA	4.2e-04
12	TCGA	Brain Lower Grade Glioma	0.0282	0.0163	5.7e-03	0.012	0.004	0.003	NA	0.009	1.4e-02	1.1e-01	1.4e-01	NA	3.2e-02
13	TCGA	Lung Adenocarcinoma	0.0228	0.0120	2.6e-03	0.023	0.019	0.023	NA	0.021	9.8e-04	2.2e-03	9.9e-04	NA	1.3e-03
14	TCGA	Pancreatic Adenocarcinoma	0.0730	0.0410	9.2e-03	0.026	0.005	0.002	NA	0.007	2.7e-02	2.0e-01	2.5e-01	NA	1.5e-01
15	TCGA	Prostate Adenocarcinoma	0.1115	0.0405	8.7e-07	0.043	0.078	0.064	NA	0.054	2.4e-05	1.4e-08	3.1e-07	NA	2.5e-06
16	TCGA	Thyroid Carcinoma	0.0980	0.0390	3.2e-07	0.070	0.073	0.052	NA	0.050	2.4e-07	1.2e-07	8.2e-06	NA	1.2e-05
17	TCGA	Uterine Corpus Endometrial Carcinoma	0.1600	0.0770	6.2e-03	0.132	0.071	0.040	NA	0.101	1.7e-04	5.0e-03	2.9e-02	NA	9.2e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.5	0.8	3.5	-1.9	0.2	-1.8	-1.9	0.9	-0.0	-0.3	-0.3	-0.2	-0.6	-0.4	-0.5	-0.7	-0.7	0.4	-0.9	-0.3
Bipolar Disorder or Schizophrenia	0.3	0.6	4.1	0.0	1.0	-1.2	-1.0	2.0	-0.4	0.4	-0.4	0.4	0.6	0.3	0.3	0.2	0.1	1.4	0.4	0.5
Depressed Affect (Nagel 2018)	0.6	1.2	3.5	-1.4	0.4	-0.6	0.3	0.9	1.0	0.5	0.0	-1.7	-1.0	-1.6	-1.9	-1.6	-1.4	-0.5	-1.1	-0.8
Depression (Nagel 2018)	0.3	0.5	1.5	-0.7	-0.5	-1.2	-0.8	-1.0	-0.2	0.6	-0.9	0.3	0.8	-0.1	-0.1	0.9	1.1	-0.5	-0.4	-0.1
Intelligence (Savage-Jansen 2018)	1.0	3.0	13.8	-0.0	-1.1	-1.7	-2.5	-0.7	-0.2	0.6	-3.7	2.7	1.3	0.9	1.3	2.5	3.0	-0.3	-0.7	-0.0
Neuroticism (Nagel 2018)	0.5	1.2	2.7	-1.6	-0.4	-0.8	-0.5	0.7	1.5	-0.3	0.3	-0.9	-0.9	-1.6	-1.5	-1.6	-1.4	0.2	-1.2	-1.4
Schizophrenia (2018)	0.4	0.9	3.5	1.6	1.1	-0.1	0.2	1.9	-0.5	0.8	-0.3	0.8	1.1	0.8	0.7	0.9	0.8	1.1	1.1	0.8
Schizophrenia vs Biploar Disorder	0.2	0.3	1.1	-0.2	-0.8	-0.7	-0.1	-0.4	0.7	0.3	-0.4	-0.5	0.2	-0.4	-0.2	0.6	0.8	-1.0	-0.3	-0.3
Worry (Nagel 2018)	0.5	1.0	2.7	-1.2	-0.3	0.2	-0.3	-0.7	0.9	-0.3	1.3	-1.2	-0.8	-1.3	-1.1	-1.5	-1.6	1.1	-0.7	-1.1
Alzheimer’s Disease (in mother)	1.7	2.0	3.6	1.5	-0.0	-0.7	-1.2	-1.8	-1.5	-0.6	-1.2	1.5	1.8	1.8	1.8	1.9	1.8	0.8	1.0	1.3
Alzheimer’s Disease (in father)	1.6	1.7	12.2	-0.1	-1.4	-2.4	-1.9	-3.5	-0.3	-1.3	-1.1	0.3	0.5	0.6	0.9	0.6	0.4	0.5	-0.2	-0.0
Alzheimer’s Disease (including proxy)	3.9	5.6	17.7	1.2	-1.9	-3.2	-3.4	-4.2	-1.3	-1.8	-2.8	2.4	2.2	2.1	2.7	2.7	2.7	0.3	0.1	0.8
Crohns Disease (2017)	0.4	0.9	5.1	-0.8	-0.5	-0.3	0.0	1.5	0.8	-0.0	-0.6	-0.4	-0.4	-1.3	-1.4	-0.5	-0.1	-2.3	-1.1	-1.0
Irritable Bowel Disease (IBD)	0.8	2.0	8.7	-0.6	-1.4	-0.9	-0.2	0.7	1.6	0.0	-1.3	-1.2	-1.3	-2.0	-1.9	-0.8	-0.4	-2.9	-1.5	-1.6
Ulcerative Colitis (UC)	1.3	2.4	8.1	0.1	-1.9	-1.2	-0.4	-0.3	2.0	0.3	-1.2	-1.8	-2.0	-2.2	-2.0	-0.9	-0.5	-2.9	-1.4	-1.9
Major Depression (MDD)	0.3	0.4	1.3	-0.7	0.3	-0.0	-0.6	0.9	0.3	0.7	0.0	-1.0	0.3	0.2	0.0	-1.0	-1.0	1.1	0.3	0.4
Reaction Time	1.3	2.4	7.8	-1.1	-1.8	-1.1	-1.9	-1.4	1.6	-2.8	0.9	-1.2	-2.2	-1.8	-1.3	-0.9	-0.8	-0.1	-1.0	-2.1
Verbal and Numeric Reasoning (VNR)	0.9	2.1	8.8	0.2	-0.6	-1.9	-1.6	-0.0	-0.5	-0.0	-3.0	2.8	1.2	1.3	1.7	1.6	2.0	0.0	-0.1	0.3
Breast Cancer	0.3	0.7	5.0	-1.0	-0.0	0.2	0.1	-2.2	-0.8	0.2	0.4	1.4	1.1	0.5	0.6	0.9	1.0	-0.1	0.1	0.1
Ovarian Cancer	1.5	1.9	4.4	-1.1	1.5	2.0	0.6	0.5	-1.8	0.6	2.0	0.8	1.4	1.5	1.2	0.9	0.5	2.1	1.6	1.6
Prostate Cancer	1.3	1.8	5.5	0.4	-0.3	-1.4	-1.1	-1.9	-1.2	0.3	-1.1	0.8	1.7	1.4	1.4	2.2	2.3	-0.0	0.5	1.3
Age at First Birth	0.2	0.3	1.4	-0.3	-0.1	1.0	-0.7	-1.1	0.3	-1.2	0.2	0.1	0.3	0.3	0.4	0.4	0.5	0.8	0.1	-0.1
Bipolar Disorder (2011)	0.4	0.4	1.3	-0.6	0.2	-1.1	-1.1	0.1	-0.6	0.0	-0.6	0.8	0.1	0.4	0.6	0.5	0.3	1.1	0.6	0.3
Body Mass Index (BMI) (2010)	0.3	0.4	1.9	0.7	0.6	1.4	0.9	1.2	-0.3	-0.2	0.6	-0.4	0.5	0.2	-0.1	0.2	0.2	-0.3	0.1	0.5
Coronary Artery Disease (CAD)	1.0	1.2	4.3	-0.3	-1.0	0.2	0.2	-1.0	1.0	-1.2	1.3	-2.1	-0.7	-1.3	-1.6	-0.6	-0.4	-1.8	-1.1	-1.2
Crohns Disease (2012)	0.4	0.7	2.3	-0.7	0.5	0.1	0.7	1.5	0.3	-0.0	0.3	-1.1	-0.1	-1.0	-1.4	-0.8	-0.6	-1.4	-0.8	-0.1
Mean Putamen Volume	0.5	0.6	2.2	-0.3	-0.3	0.5	0.0	-0.9	0.7	0.6	-0.1	-1.5	-0.7	-1.1	-1.3	-0.7	-0.6	-0.9	-0.7	-0.6
Fasting Glucose	0.4	0.4	2.5	0.6	0.3	-0.3	0.2	1.6	-0.4	1.2	-1.0	0.7	0.1	0.1	-0.0	-0.3	-0.3	0.3	0.9	0.3
HbA1C	1.2	1.4	3.5	-0.7	-1.4	-0.9	-0.6	-0.0	1.8	-0.6	0.2	-1.9	-1.2	-0.9	-0.6	-1.3	-1.1	-1.5	-1.4	-1.8
HDL Cholesterol	0.9	1.5	6.1	1.1	-0.1	-0.0	-0.0	-0.1	-0.9	0.9	-0.8	1.9	1.5	1.4	1.5	2.4	2.5	-0.2	0.5	1.0
LDL Cholesterol	1.5	2.4	5.5	-0.5	-1.3	0.4	0.2	-0.5	2.2	-0.9	0.6	-1.5	-2.3	-2.2	-2.0	-1.9	-1.9	-0.8	-1.5	-2.3
Lupus	0.7	1.1	6.6	-2.6	-0.5	-0.2	-1.3	0.3	1.0	0.0	-1.0	-0.8	-0.8	-1.2	-1.1	-1.1	-0.9	-0.4	-0.7	-1.2
Neuroticism (2016)	0.2	0.3	2.1	0.3	0.4	0.3	0.2	-1.5	-0.3	-1.1	0.6	0.1	-0.3	-0.3	-0.3	-0.4	-0.4	0.7	0.6	0.1
Primary Biliary Cirrhosis	0.4	0.5	2.4	0.4	-0.8	-1.1	-0.7	-1.6	-0.3	-0.1	-0.1	-0.8	0.4	-0.1	-0.3	1.0	1.2	-0.8	-0.1	0.3
Rheumatoid Arthritis	0.8	1.0	4.0	2.0	-1.3	-0.3	-0.2	-0.1	-0.1	0.8	-1.2	1.5	0.5	0.5	0.9	1.5	1.8	-0.7	-0.3	-0.2
Schizophrenia (2014)	0.2	0.5	3.5	0.4	0.2	-1.3	-1.1	1.9	0.2	0.4	-0.8	0.2	0.1	-0.1	-0.0	0.0	0.1	0.7	0.1	-0.1
Triglycerides	0.1	0.2	1.3	-0.5	0.4	-0.5	-0.0	-0.2	-0.1	-1.1	-0.1	-0.1	-0.1	-0.2	0.0	-0.3	-0.6	-0.2	-0.2	-0.2
Type 2 Diabetes (T2D) (2012)	3.5	4.1	8.6	2.0	2.3	1.8	1.8	0.5	-2.9	0.2	0.9	1.5	2.7	2.0	1.7	2.6	2.6	1.1	2.1	2.9
Ulcerative Colitis	0.8	1.1	3.0	0.8	-1.2	-1.1	-0.1	-0.3	1.3	-0.1	-1.0	-1.7	-0.8	-1.4	-1.4	-0.6	-0.4	-1.5	-1.3	-1.1
Blood Eosinophil Count	0.8	6.2	14.0	-0.4	-3.7	-3.3	-3.0	-3.4	2.8	-3.0	-3.1	-0.2	-1.9	-2.1	-1.4	-0.6	0.2	-2.9	-2.6	-3.0
Blood Platelet Count	0.5	6.2	37.0	-6.1	-0.9	-3.4	-4.2	-2.5	0.1	-2.8	-1.5	2.8	1.8	0.7	1.7	1.5	1.9	1.5	0.4	-0.5
Blood Red Count	0.2	2.3	11.7	-3.4	-0.6	-1.4	-0.4	-2.3	-0.2	-1.9	1.8	-3.2	-0.1	-0.8	-1.1	0.0	-0.2	-0.5	-0.1	0.2
Blood White Count	2.8	21.0	65.8	-0.7	-5.8	-7.0	-7.8	-7.7	1.9	-2.2	-8.1	4.1	0.7	0.5	2.0	3.7	4.9	-2.4	-2.7	-2.6
Heel T-Score	1.9	15.0	33.8	-4.5	-4.7	-4.4	-5.5	-0.6	5.2	0.3	-3.5	-4.0	-2.4	-3.8	-3.5	-1.0	0.1	-4.9	-5.8	-4.3
BMI	0.1	0.8	3.8	0.7	1.3	0.3	1.1	1.9	-0.3	-0.0	-0.3	-0.1	-0.4	-0.2	-0.6	-1.6	-1.7	-0.6	0.0	0.4
Height	1.2	22.7	45.3	-6.0	-2.2	1.2	-2.8	2.0	6.3	0.9	3.4	-4.7	-6.2	-6.3	-5.9	-6.5	-6.7	0.0	-4.8	-5.7
Waist Hip Ratio (WHR)	1.4	6.1	12.8	-1.6	-2.9	-2.1	-2.6	-3.2	2.6	-0.2	-1.2	-2.4	-3.6	-2.7	-2.5	-2.6	-2.4	-1.3	-2.7	-3.0
Systolic Blood Pressure	4.3	21.4	54.0	5.0	0.6	0.7	0.5	-2.4	-4.6	4.3	-2.9	6.0	6.0	5.9	6.2	7.2	7.3	2.2	3.3	4.2
Smoking Status	1.8	4.3	9.4	-2.7	-0.8	-1.7	-0.6	-0.1	3.0	0.1	0.3	-2.7	-2.1	-2.6	-2.5	-3.0	-3.1	-0.1	-2.0	-2.3
Allergy or Eczema	0.2	0.6	2.6	0.0	-1.1	-0.8	-1.6	-1.1	0.7	-0.9	-1.0	0.8	-0.1	-0.2	0.1	0.0	0.2	0.0	-0.5	-1.0
Cardiovascular Disease	1.4	4.5	13.6	3.7	-0.2	-1.5	0.0	-1.4	-2.0	2.0	-2.2	2.6	2.1	2.6	2.9	2.6	2.7	0.8	1.7	1.6
Hypothyroidism (self reported)	0.2	0.5	2.2	-1.5	0.0	-0.1	-1.3	0.0	-0.2	0.2	-0.8	-1.1	0.2	-0.4	-0.6	-0.3	-0.3	-0.9	-1.1	-0.1
Respiratory disease	0.8	1.8	7.2	2.7	0.6	0.7	1.5	0.4	-1.2	-0.5	0.8	1.0	1.9	1.5	1.4	1.6	1.4	0.8	1.2	1.4
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.5	1.2	1.3	1.1	0.3	1.3	-1.1	1.9	-1.7	0.9	1.2	1.1	1.0	0.9	0.9	0.8	0.8	0.9
Lung FEV1/FVC ratio	2.1	10.7	46.9	-0.9	-3.6	-4.7	-4.6	-5.9	1.9	3.1	-6.8	1.7	-0.6	-0.3	0.8	2.5	3.1	-0.8	-2.4	-1.9
Lung FVC	0.6	3.0	7.9	-2.8	-0.8	-0.4	-0.5	0.7	2.0	-0.8	2.5	-2.0	-2.1	-1.4	-1.4	-2.6	-2.8	-0.0	-1.3	-1.5
Neuroticism	0.3	0.8	2.3	-1.0	-0.1	0.1	-0.3	0.7	1.1	-0.6	0.7	-0.5	-0.8	-1.5	-1.3	-1.3	-1.2	0.6	-0.7	-1.2
Chronotype (morning person)	0.4	1.0	3.0	1.1	0.3	1.4	0.9	-1.1	-1.0	1.7	0.4	0.1	0.9	0.8	0.9	0.8	0.6	1.0	1.4	0.9
Hair Pigment	0.0	0.7	4.2	-0.6	-0.6	-1.7	-1.2	-1.0	0.2	-2.0	-0.8	0.6	0.1	-0.1	0.2	0.3	0.4	0.4	-0.4	-0.4
Tanning	0.2	2.2	6.4	-2.4	-1.2	-0.8	0.0	0.6	1.7	2.5	-0.3	-2.0	-1.4	-1.5	-1.7	-1.1	-1.0	-1.4	-1.7	-1.3
Hand grip strength (left)	3.1	8.1	14.9	2.4	3.8	3.1	3.8	2.7	-3.2	2.1	2.3	1.7	3.0	3.4	2.6	1.4	0.7	3.0	2.9	3.9
Number of treatments/medications taken	1.1	2.1	5.2	0.8	-0.7	0.3	0.9	1.2	1.2	-1.7	0.7	-1.9	-1.3	-2.2	-2.3	-1.4	-1.1	-2.1	-1.1	-1.6
Average weekly spirits intake	0.3	0.4	1.3	-0.8	0.9	0.7	-0.1	1.1	-0.1	-0.4	0.5	-0.9	0.3	-0.2	-0.4	-0.8	-0.8	0.6	0.2	0.2
Sensitivity / hurt feelings	0.6	1.0	10.6	-1.2	0.7	0.2	-0.6	3.3	0.2	-1.1	0.3	1.1	0.5	0.1	0.3	-0.4	-0.3	0.6	0.3	-0.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.3	-0.3	0.0	-0.0	0.3	-0.2	0.5	1.1	-0.1	-1.0	-0.2	-1.0	-1.1	-0.2	-0.1	-0.8	-0.8	-0.4
Hearing difficulty/problems: Yes	1.0	1.6	4.5	-1.3	-1.4	-0.6	-1.1	0.8	2.1	1.7	-1.1	-0.0	-0.6	-1.4	-0.8	-0.0	0.3	-1.2	-2.0	-2.1
Relative age of first facial hair	0.2	0.3	1.5	-0.7	-0.6	0.4	-0.2	-1.1	0.1	1.2	-0.4	0.2	-0.3	0.2	0.5	-0.2	-0.3	0.8	0.6	-0.5
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	6.6	-0.9	-1.3	-0.2	-1.2	0.8	2.0	-0.9	-1.1	-1.5	-2.1	-2.6	-2.4	-1.1	-0.7	-2.3	-2.2	-2.5
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.3	-1.2	-0.2	-0.5	0.2	1.3	1.1	0.3	-0.2	-1.3	-0.8	-1.2	-1.2	-2.1	-2.0	-1.1	-0.6	-0.9
Ever had hysterectomy (womb removed)	0.5	0.6	3.0	0.4	-0.4	-0.1	0.0	-1.7	0.8	-0.6	-0.3	-0.1	-1.0	-0.8	-0.6	-1.0	-1.1	0.2	-0.3	-0.9
Systolic blood pressure, automated reading	3.5	10.1	20.6	3.5	1.2	1.3	1.0	-1.3	-3.5	2.5	-1.5	3.8	4.4	4.2	4.1	4.5	4.5	1.6	2.6	3.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	1.6	-0.1	0.1	0.4	0.4	0.1	-0.1	1.3	0.0	-0.6	-0.1	-0.2	-0.4	-0.6	-0.4	-1.2	0.1	0.1
Angina	2.8	3.7	8.1	0.9	2.2	1.8	1.0	1.5	-2.4	0.8	-0.4	1.8	2.9	2.2	2.1	2.4	2.1	1.7	2.3	2.2
Medication for hormone replacement therapy	0.6	0.6	1.7	0.8	-0.7	-1.3	0.6	0.6	0.4	1.1	-1.3	-0.2	-0.9	-0.6	-0.5	-1.0	-0.9	-0.6	-0.4	-0.7
Vitamin and mineral supplements	0.6	0.9	3.5	0.4	-0.6	-1.6	-0.6	-1.4	0.2	1.9	-1.8	0.5	-0.5	0.4	0.5	-0.4	-0.3	-0.6	-0.9	-0.4
Supplements: Zinc	1.0	1.1	6.4	-0.2	1.2	1.7	1.3	2.5	-0.1	-1.0	2.0	0.3	-0.0	-0.2	-0.4	-0.1	-0.2	0.6	0.4	0.3
Medication: Co-codamol	3.1	3.6	11.6	1.6	0.7	0.0	-0.2	-0.1	-1.7	-0.7	-0.1	3.4	2.1	2.5	2.9	2.6	2.5	2.2	2.1	1.5
Medication: Metformin	0.3	0.5	3.0	0.4	0.6	0.1	0.9	1.7	-0.6	0.0	-0.2	-0.1	0.3	0.6	0.6	-0.3	-0.4	0.7	1.1	0.4
Diabetes (father)	1.0	1.2	6.3	0.1	0.9	1.3	1.6	2.5	-0.6	1.3	1.2	0.2	-0.3	0.3	0.2	-1.3	-1.5	0.1	1.2	0.5
Diabetes (mother)	0.7	0.9	3.1	0.3	1.5	1.7	1.4	1.8	-0.9	0.3	0.6	-0.1	0.5	0.5	0.3	-0.3	-0.5	0.8	1.1	0.9
Severe depression (siblings)	0.2	0.3	1.0	-0.3	-0.5	-0.3	-0.7	0.7	0.5	0.4	-1.0	0.1	-0.2	-0.3	-0.2	-0.3	-0.2	-1.0	-0.5	-0.4
Pack years adult smoking proportion	1.8	2.7	7.3	-1.2	-0.9	-0.5	-0.0	-1.6	1.8	-1.2	1.6	-2.1	-2.1	-1.8	-1.7	-2.6	-2.7	-1.1	-1.1	-1.6
Impedance of leg (right)	1.6	7.9	24.5	-2.1	-5.0	-3.6	-3.4	-3.5	3.5	-1.6	-0.6	-1.7	-2.4	-2.8	-2.0	0.5	1.0	-2.1	-3.6	-3.8
Leg fat-free mass (left)	0.6	3.4	12.7	-1.2	1.1	1.7	1.2	2.1	1.2	1.0	1.8	-2.0	-2.0	-1.7	-2.1	-3.3	-3.6	-0.1	-1.1	-0.8
Trunk fat percentage	0.8	3.3	7.4	-0.6	-0.7	-0.3	0.2	1.0	1.8	-0.6	0.4	-2.7	-2.2	-2.5	-2.6	-2.7	-2.6	-1.9	-1.9	-1.8
Hand grip strength (right)	1.3	3.5	7.9	1.9	2.4	1.9	2.8	2.5	-1.9	0.7	2.1	0.8	1.8	2.0	1.6	0.7	0.1	2.0	1.6	2.4
Townsend deprivation index at recruitment	2.1	3.0	6.7	-1.6	-0.6	-0.1	0.5	0.2	1.8	0.2	1.0	-2.4	-2.4	-2.4	-2.6	-2.6	-2.3	-0.9	-1.5	-2.0
Current tobacco smoking	1.1	1.8	4.5	-0.8	0.3	0.7	1.2	0.6	1.5	0.7	0.7	-2.1	-1.3	-1.8	-2.0	-2.1	-2.1	-0.2	-1.0	-1.1
Average weekly fortified wine intake	2.0	2.4	5.6	-1.9	-0.6	-1.0	-0.9	0.8	1.8	-1.6	1.0	-1.5	-1.6	-1.7	-1.7	-2.4	-2.3	-0.8	-1.6	-1.6
Maternal smoking around birth	1.4	2.1	6.2	0.2	2.1	2.2	2.5	0.8	-1.0	2.4	2.0	-1.3	0.1	0.3	-0.6	-1.3	-1.5	-0.1	0.8	1.4
Fed-up feelings	0.8	1.4	3.9	-1.0	0.4	-0.7	1.1	1.1	1.1	0.9	0.0	-1.9	-1.2	-1.4	-1.7	-2.0	-1.9	-0.2	-0.5	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.4	-1.2	-0.7	-0.7	-0.9	-1.2	0.2	-0.1	0.1	-0.2	0.4	-0.5	-0.3	0.7	0.8	-0.2	-0.6	-0.5
Relative age voice broke	0.4	0.6	3.8	0.4	0.2	1.1	-0.2	-0.1	-0.5	0.8	0.1	0.0	0.4	0.7	0.5	1.0	0.8	1.9	0.9	0.3
Taking other prescription medications	0.8	1.2	5.3	0.7	0.7	1.3	0.9	2.3	0.2	-2.1	1.5	-0.9	-0.3	-0.8	-1.0	-0.8	-0.7	-1.3	0.1	-0.3
Age when periods started (menarche)	0.5	1.3	5.6	-1.8	-1.2	-1.7	-2.4	-0.4	0.8	-0.6	-0.7	-0.0	-0.8	-1.0	-0.9	0.6	1.0	-1.0	-1.4	-0.8
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	4.5	-0.8	0.1	0.6	0.3	-0.9	1.2	0.7	-0.0	-1.1	-1.4	-1.0	-1.0	-2.1	-2.1	-0.2	-0.5	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	2.6	6.0	11.7	-2.1	-2.3	-1.7	-2.1	0.7	3.3	1.1	-1.7	-2.6	-2.2	-3.3	-3.2	-1.8	-1.1	-3.4	-3.3	-3.1
Tinnitus: Yes, but not now, but have in the past	1.3	1.3	4.1	0.4	2.0	1.4	1.7	1.6	-1.4	-0.1	1.6	0.1	0.7	0.5	0.2	0.3	-0.0	1.4	1.4	1.1
Qualifications: CSEs or equivalent	0.8	1.0	8.7	1.2	-0.4	-2.0	-0.1	-2.9	0.3	0.5	-0.9	-0.5	-0.5	-0.0	0.0	-0.8	-0.8	-0.0	-0.3	-0.2
Serious illness, injury or assault to yourself	0.3	0.4	2.2	-0.1	-0.4	0.6	-0.8	0.2	0.8	0.0	-1.5	0.4	-0.5	-0.5	-0.2	-0.3	-0.1	-0.1	-0.6	-1.0
High blood pressure	1.5	4.3	17.9	4.2	0.5	0.0	1.0	0.1	-2.1	0.7	-1.7	3.2	2.1	2.2	2.5	2.5	2.6	0.2	2.0	1.6
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.0	1.0	-1.3	-0.6	-1.4	-0.9	0.7	-0.0	-1.2	1.1	-0.4	-0.1	0.3	0.3	0.5	0.1	-0.5	-0.9
Multivitamins +/- minerals	2.5	3.2	7.9	0.8	1.4	2.0	0.7	0.8	-1.9	-0.5	0.7	1.8	2.4	1.8	1.8	2.8	2.6	1.7	2.3	1.8
Stomach or abdominal pain in last month	0.8	1.0	3.1	-0.3	-0.8	-1.2	-0.3	0.3	1.1	0.1	0.7	-0.8	-1.8	-1.0	-0.9	-1.4	-1.4	-0.3	-1.3	-1.2
Supplements: Glucosamine	3.6	4.8	8.8	-2.1	-1.4	-0.5	-1.2	1.7	3.0	-1.6	0.8	-2.4	-2.5	-2.7	-2.6	-2.7	-2.5	-2.1	-2.6	-2.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.0	0.1	-0.2	-0.2	-0.2	1.3	1.3	-1.3	0.8	-0.2	-1.4	-0.9	-0.7	-1.4	-1.4	-0.6	-0.5	-1.1
Medication: Atenolol	1.9	2.4	7.0	2.6	-0.3	-0.0	-0.3	-0.9	-1.1	0.6	-2.1	2.4	1.6	1.4	1.7	2.4	2.4	0.2	0.8	0.9
Medication: Levothyroxine sodium	0.1	0.2	0.7	-0.6	0.5	0.1	-0.3	0.3	-0.6	-0.3	-0.6	-0.5	0.8	0.1	-0.0	-0.0	0.0	-0.6	-0.2	0.4
Sitting height	0.2	1.2	7.2	-0.1	0.8	1.5	0.3	2.1	1.0	2.7	0.7	-0.0	-0.2	-0.3	-0.5	-1.2	-1.3	0.2	-1.1	-0.2
Chronic bronchitis/emphysema (father)	1.8	2.1	7.9	-0.2	-1.8	-0.4	-0.7	-1.3	1.7	-1.2	-0.6	-1.3	-1.4	-1.9	-1.7	-1.2	-0.9	-2.8	-1.6	-1.7
High blood pressure (mother)	1.2	1.7	6.2	2.5	-0.7	-0.2	1.1	1.1	1.5	0.2	-0.5	0.7	-2.2	-1.3	-1.0	-1.0	-0.9	-1.8	-1.3	-1.6
Body mass index (BMI)	0.4	1.5	4.7	1.0	1.4	1.0	1.9	1.9	-0.1	-0.1	0.4	-1.0	-0.9	-0.8	-1.2	-2.1	-2.2	-1.2	-0.1	0.2
Impedance of leg (left)	1.0	5.0	14.7	-1.8	-3.8	-2.8	-2.5	-2.8	2.7	-1.1	-0.3	-1.8	-1.9	-2.4	-1.8	0.4	0.8	-1.8	-2.9	-2.9
Leg predicted mass (left)	0.7	3.4	12.7	-1.1	1.1	1.6	1.2	2.2	1.2	0.9	1.8	-2.0	-2.0	-1.7	-2.2	-3.4	-3.6	-0.2	-1.1	-0.8
Trunk fat mass	0.9	4.1	10.8	-0.9	-0.3	0.2	0.3	1.5	1.9	-0.2	0.7	-2.8	-2.5	-2.6	-2.9	-3.3	-3.3	-1.7	-2.0	-1.9
Waist circumference	0.7	2.7	8.8	-0.3	-0.2	-0.1	0.3	0.4	1.6	-0.1	-0.2	-2.1	-2.3	-2.1	-2.2	-3.0	-2.9	-1.2	-1.6	-1.5
Number of incorrect matches in round	0.5	0.9	2.6	-1.0	-0.3	0.6	-0.3	-0.2	1.2	0.8	0.3	-1.6	-1.1	-1.1	-1.2	-1.3	-1.2	-0.7	-0.8	-0.9
Past tobacco smoking	0.9	1.6	7.9	2.8	0.6	2.1	1.5	-0.5	-1.6	-0.6	0.7	0.2	0.8	0.6	0.1	1.5	1.6	-1.2	0.5	1.3
Alcohol usually taken with meals	1.0	1.5	4.0	0.1	-0.9	-1.9	-2.0	-1.6	-0.6	-0.7	-1.7	1.1	1.5	0.8	1.0	1.8	1.8	0.0	-0.4	0.4
Nervous feelings	0.6	1.1	4.4	-0.4	0.1	-0.1	0.1	0.4	1.0	-1.2	1.0	-0.5	-1.1	-1.2	-0.9	-2.0	-2.1	0.9	-0.5	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.9	1.4	0.6	0.3	1.2	-0.1	0.3	-0.2	0.4	-0.2	-0.3	-0.7	-0.8	-0.2	-0.0	-0.7	-0.4	-0.1
Hearing difficulty/problems with background noise	1.0	1.6	11.2	-1.4	0.0	0.7	0.3	3.4	1.6	1.9	0.0	0.5	-1.0	-1.0	-0.5	-0.9	-0.8	-0.2	-0.8	-1.6
Hair/balding pattern: Pattern 2	0.4	0.5	2.3	0.1	-0.7	-1.5	-0.8	-0.9	0.1	-1.0	-0.3	1.0	0.1	-0.0	0.3	0.6	0.7	-0.8	0.4	-0.2
Had menopause	0.4	0.5	2.0	0.1	-0.1	0.1	0.1	0.5	0.8	-1.4	-0.1	-0.3	-0.8	-0.8	-0.6	-1.2	-1.2	-0.7	-0.3	-0.9
Had other major operations	0.5	0.6	5.2	0.3	0.3	0.5	-0.0	1.0	-0.2	2.3	-0.9	1.0	0.1	0.8	0.9	-0.1	-0.1	0.5	0.4	0.2
Forced vital capacity (FVC)	0.6	2.3	6.0	-2.2	-1.1	-0.3	-0.8	-0.2	1.9	0.1	1.9	-1.2	-2.4	-1.5	-1.3	-2.0	-2.1	0.4	-1.1	-1.7
Heel bone mineral density (BMD) T-score, automated (right)	2.6	6.1	13.4	-2.0	-2.4	-1.6	-2.4	0.3	3.4	0.3	-1.9	-2.0	-2.3	-3.3	-3.1	-1.8	-1.0	-3.7	-3.3	-3.3
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	5.5	0.1	0.9	1.9	2.3	1.8	0.3	-0.0	1.9	-1.1	-1.3	-1.3	-1.6	-1.3	-1.3	-0.5	0.0	-0.4
Qualifications: None of the above	1.1	2.4	5.0	-0.6	0.0	0.4	1.7	1.6	0.7	-2.1	1.5	-1.3	-1.4	-1.9	-2.1	-2.2	-2.0	-2.2	-0.3	-1.1
Financial difficulties in last 2 years	0.7	0.9	7.0	-1.3	-0.3	-0.2	0.2	0.2	0.9	2.6	-0.7	-0.3	-0.7	-0.9	-0.7	-0.7	-0.4	-1.1	-0.5	-1.0
Mouth/teeth dental problems	1.0	1.5	4.6	0.4	0.7	-0.4	-0.4	-1.1	-1.5	0.1	-0.4	0.3	2.2	1.8	1.5	1.9	1.9	0.6	0.5	1.8
Heart attack	0.4	0.5	1.7	-1.2	-0.1	-0.5	-1.3	-1.0	0.1	-0.9	-0.3	0.6	0.6	0.3	0.4	0.8	0.8	0.8	-0.1	-0.1
Allergy	0.3	0.7	3.3	-1.8	0.1	-0.9	0.0	-0.1	0.4	0.4	0.0	-1.2	-0.9	-0.7	-0.9	-1.1	-1.1	-0.8	-0.6	-0.1
Pain all over the body in last month	1.2	1.3	3.1	0.0	-0.6	0.6	0.5	0.2	1.4	0.7	0.9	-1.5	-1.3	-1.6	-1.7	-1.4	-1.2	-1.5	-1.4	-1.1
Diabetes (self-reported)	0.8	1.3	2.9	0.9	1.1	0.9	0.4	1.7	-1.3	0.6	-1.1	1.3	1.4	1.5	1.5	0.7	0.7	0.8	1.2	1.0
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	0.5	-0.3	0.3	-0.3	0.4	0.1	0.4	-0.5	0.6	0.3	0.1	0.3	0.5	0.5	-0.2	0.3	-0.1
Medication: Ramipril	0.9	1.1	4.3	1.6	-0.8	-0.7	-0.7	0.2	-0.4	1.0	-1.6	1.2	0.6	0.5	0.9	1.9	2.1	-0.1	0.2	-0.3
Medication: Simvastatin	1.3	2.0	6.8	0.8	1.1	0.3	0.4	-0.2	-2.0	0.9	-0.5	0.4	2.6	1.7	1.5	2.1	1.9	0.7	1.6	1.8
Fluid intelligence score	0.6	1.3	4.8	0.8	-0.4	-0.7	-1.5	-0.3	-0.2	-0.1	-2.1	2.2	0.9	0.7	0.8	1.6	2.0	-0.7	-0.5	0.2
Illnesses of siblings	0.7	0.9	2.6	-1.5	-0.5	-0.3	-0.2	0.7	1.1	0.4	0.3	-1.6	-0.8	-1.1	-1.4	-0.4	-0.4	-1.4	-1.6	-0.5
Neuroticism score	0.2	0.4	1.7	-0.9	0.3	-0.4	0.2	1.1	0.5	-0.6	0.4	-0.1	-0.2	-0.5	-0.3	-0.9	-1.0	1.3	-0.1	-0.6
Weight	0.9	4.4	14.1	-1.2	0.4	1.0	0.8	1.9	1.9	0.2	1.4	-2.6	-2.7	-2.5	-2.8	-3.7	-3.8	-1.2	-1.7	-1.5
Impedance of arm (right)	0.8	3.9	11.3	-2.0	-3.2	-2.8	-3.4	-3.2	2.2	-1.5	-0.9	-1.3	-1.0	-1.3	-0.8	0.3	0.5	-0.1	-1.9	-2.2
Arm fat percentage (right)	0.3	1.2	4.3	0.0	0.2	0.3	0.7	0.6	0.7	-0.3	0.1	-1.8	-1.4	-1.3	-1.5	-2.1	-2.1	-1.1	-0.8	-0.7
Trunk fat-free mass	0.5	2.8	8.6	-1.4	0.9	2.0	0.8	1.4	1.4	1.2	2.2	-1.5	-1.9	-1.6	-1.9	-2.7	-2.9	0.3	-1.1	-0.9
Hip circumference	0.4	1.9	6.5	0.1	1.7	1.8	1.9	2.5	0.7	0.3	1.2	-1.3	-0.7	-1.1	-1.5	-2.0	-2.1	-0.2	-0.5	-0.1
Time employed in main current job	1.1	1.2	4.8	0.2	0.6	-0.3	0.1	0.4	-1.2	-0.3	0.6	2.2	1.2	1.6	1.9	1.0	0.9	0.9	1.2	1.3
Alcohol intake versus 10 years previously	1.5	2.2	4.5	2.0	2.0	0.6	1.8	0.1	-1.9	0.8	-0.4	1.6	1.5	1.7	1.5	1.1	0.9	1.1	2.1	1.9
Father’s age at death	0.5	0.7	2.9	0.2	-1.2	-0.7	-1.7	-0.1	0.6	-0.9	-0.7	-0.3	-0.0	-0.2	0.0	0.9	1.1	-0.3	-1.5	-0.6
Worrier / anxious feelings	0.3	0.7	2.5	-1.1	-0.1	0.3	-0.1	0.4	0.7	-1.1	1.2	-0.2	-0.5	-0.8	-0.5	-0.9	-1.1	1.6	-0.0	-0.8
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	6.9	-0.4	-1.6	-1.0	-0.4	0.2	2.3	-0.1	-0.8	-1.6	-2.5	-2.6	-2.3	-2.0	-1.6	-2.0	-2.2	-2.5
Falls in the last year	0.4	0.6	1.8	0.6	0.1	-0.8	-0.4	0.7	-0.3	0.7	-0.5	0.9	0.8	0.9	1.1	0.8	0.7	1.3	0.8	0.6
Hair/balding pattern: Pattern 3	0.2	0.3	1.8	-0.4	0.4	0.1	0.3	-0.3	0.3	0.5	0.1	-1.3	0.7	-0.4	-0.7	0.5	0.5	0.4	-0.6	0.1
Number of live births	0.5	0.7	2.4	0.2	0.3	0.7	1.6	0.4	0.6	0.0	1.0	-0.3	-1.2	-1.1	-1.1	-1.2	-1.2	0.0	0.3	-0.6
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	6.9	-2.3	-2.3	-2.1	-2.1	-1.4	2.4	0.5	-0.1	-0.5	-2.6	-1.4	-1.0	-1.3	-1.2	-0.2	-1.9	-2.2
Pulse rate	1.7	2.8	6.2	-0.5	-2.5	-2.3	-1.6	-1.5	2.1	-0.5	-1.1	-0.7	-1.6	-1.8	-1.3	-0.8	-0.5	-2.4	-2.4	-2.2
Happiness	0.3	0.3	1.6	0.2	0.7	0.6	0.7	1.3	-0.2	-0.4	0.6	-0.4	-0.0	-0.6	-0.8	0.1	0.0	-0.5	-0.6	-0.0
Noisy workplace	1.8	2.3	5.0	-1.2	-0.7	-0.9	-1.4	0.3	1.4	-0.1	-1.2	-2.1	-2.0	-1.8	-1.8	-2.2	-2.1	-1.4	-1.5	-1.4
Qualifications: A levels/AS levels or equivalent	1.2	2.6	7.5	0.8	-1.2	-1.3	-1.6	-0.6	-0.2	0.8	-2.5	2.4	1.7	1.6	2.0	2.6	2.7	0.8	0.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	3.2	1.1	0.2	-0.9	0.1	-0.8	-0.8	1.8	-1.1	1.0	0.2	0.9	1.2	0.1	-0.1	1.5	1.7	0.7
Mouth/teeth dental problems: Dentures	1.0	1.6	4.6	0.2	0.9	1.8	1.7	1.7	0.0	-0.2	2.2	-0.9	-0.9	-0.4	-0.5	-1.7	-2.1	1.4	1.1	0.1
Asthma	0.8	1.6	6.6	2.6	0.5	0.8	1.5	1.0	-1.1	-1.3	0.6	1.5	1.5	1.1	1.2	1.3	1.2	0.6	1.3	0.8
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.2	6.2	-0.3	-1.4	-1.2	0.5	-0.7	1.3	-0.3	-0.2	-1.2	-2.0	-2.1	-2.2	-1.7	-1.4	-2.5	-1.6	-1.8
Medication: Cholesterol lowering	1.5	2.3	6.7	1.8	1.9	2.6	2.5	1.3	-1.6	2.3	0.5	-0.5	1.5	0.4	-0.0	1.4	1.2	-0.5	1.1	1.4
Depression (self-reported)	2.0	2.5	6.5	1.4	1.2	0.6	1.1	0.8	-1.9	1.3	-0.1	1.7	2.5	2.1	2.0	1.6	1.5	0.4	2.0	2.0
Medication: Lansoprazole	1.2	1.3	6.2	2.5	1.1	1.1	1.6	0.5	-1.9	-0.4	1.1	-0.3	0.8	1.0	0.5	0.6	0.4	0.5	1.1	1.6
Prospective memory result	0.2	0.3	1.9	-0.6	-0.9	-0.3	-1.1	-1.4	0.2	0.0	0.2	-0.1	0.4	-0.0	0.1	0.3	0.4	-0.3	-0.2	-0.1
Lung cancer (father)	0.4	0.5	1.1	-0.3	-0.1	0.8	0.3	-0.9	0.8	-1.0	0.6	-0.3	-0.8	-0.7	-0.8	-1.0	-0.8	0.0	-0.6	-0.7
Illnesses of mother	1.0	1.2	3.7	-1.5	1.3	0.5	0.2	-1.2	-1.3	0.7	0.0	-0.6	1.8	1.2	0.8	0.5	0.2	1.9	1.2	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.0	8.9	-2.7	-2.8	-2.5	-2.8	-1.4	2.8	0.3	-0.7	-0.3	-3.0	-1.7	-1.0	-1.5	-1.4	0.1	-2.2	-2.7
Pulse wave Arterial Stiffness index	1.7	2.0	5.5	0.6	-1.9	-0.2	-1.2	-1.6	1.7	-0.5	-1.2	-0.3	-1.7	-1.5	-1.2	-0.6	-0.1	-2.2	-2.3	-2.1
Impedance of arm (left)	0.6	2.9	8.8	-1.3	-3.0	-2.7	-2.8	-2.3	1.8	-1.5	-0.8	-1.4	-1.0	-1.3	-0.9	-0.1	0.1	-0.2	-1.5	-2.1
Arm fat mass (right)	0.4	1.8	6.6	-0.3	0.5	0.9	0.9	1.1	1.0	0.1	0.7	-1.8	-1.6	-1.5	-1.8	-2.5	-2.6	-1.0	-0.9	-0.8
Trunk predicted mass	0.5	2.8	8.8	-1.5	0.8	1.9	0.7	1.3	1.4	1.2	2.2	-1.5	-2.0	-1.6	-1.9	-2.8	-3.0	0.3	-1.1	-0.9
Standing height	1.0	10.4	21.8	-4.7	-2.2	0.3	-2.2	0.1	4.5	0.4	2.6	-3.7	-4.0	-4.1	-3.9	-3.7	-3.8	0.0	-3.7	-3.8
Length of working week for main job	0.6	0.7	4.5	-0.2	-1.1	-0.8	-0.5	-2.1	0.6	0.6	-0.8	1.2	-0.9	-0.3	0.1	-0.1	0.1	-0.7	-0.3	-0.7
Exposure to tobacco smoke at home	0.2	0.3	0.8	-0.5	0.4	-0.6	-0.2	-0.3	-0.3	0.0	0.6	0.4	-0.3	0.2	0.4	-0.7	-0.9	0.8	0.8	0.2
Breastfed as a baby	2.7	3.4	16.2	-2.0	-1.8	-4.0	-3.4	-0.3	2.1	0.7	-3.2	-0.1	-0.8	-0.9	-0.5	-0.1	0.2	-0.2	-1.9	-1.6
Tense / ‘highly strung’	0.7	1.1	6.1	-1.9	0.7	0.6	1.0	-0.5	-0.3	-0.3	2.5	-1.9	0.0	-0.5	-0.8	-0.7	-1.0	0.9	-0.1	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	7.2	1.5	0.8	-0.2	0.1	-0.9	-1.9	0.6	-1.2	2.5	2.7	2.4	2.5	1.8	1.9	1.7	2.2	1.9
Hair/balding pattern: Pattern 4	0.4	0.9	3.0	1.6	-0.1	-0.2	-0.4	1.3	-1.1	-0.0	-0.6	1.7	0.9	1.1	1.3	1.1	1.0	0.1	0.4	0.6
Birth weight of first child	0.6	1.0	5.6	-1.2	1.1	0.5	0.2	0.6	-0.3	0.9	0.4	-0.5	-0.9	0.2	-0.0	-2.1	-2.4	1.2	0.9	0.3
Peak expiratory flow (PEF)	0.6	1.4	3.8	-1.9	-1.1	-1.3	-1.2	-0.3	1.5	0.1	-0.2	-0.2	-1.5	-1.1	-0.9	-1.1	-1.1	-0.5	-1.9	-1.4
Pulse wave reflection index	0.6	0.7	2.4	0.7	-1.2	0.4	-0.3	-0.7	1.2	1.0	-0.6	-0.1	-1.4	-0.9	-0.6	0.0	0.3	-0.3	-1.1	-1.6
Ever highly irritable/argumentative for 2 days	0.4	0.4	2.4	0.5	0.1	-0.1	0.7	0.6	0.1	-0.5	1.5	-0.8	-0.7	-0.3	-0.3	-0.9	-1.0	-0.2	-0.1	-0.2
Loud music exposure frequency	0.6	0.6	1.9	-0.0	-0.2	-0.8	-0.8	0.1	0.5	-1.2	0.2	-1.2	-0.8	-0.7	-1.1	-0.5	-0.3	-1.2	-1.4	-0.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.7	0.5	-0.6	-1.0	-0.5	-0.2	0.4	1.0	-1.1	1.1	0.4	0.3	0.5	1.2	1.3	-0.5	-0.4	-0.1
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	4.4	-1.0	-1.4	-1.1	-1.5	0.9	1.8	0.2	-1.6	0.4	-1.4	-1.6	-1.1	-1.0	-0.6	-1.4	-1.5	-2.1
Blood clot in the leg (DVT)	1.6	2.1	4.7	1.3	0.3	-0.1	-1.4	-0.6	-1.6	0.5	-1.7	1.2	2.1	1.9	1.9	2.2	2.2	0.9	0.9	1.5
Medication: Paracetamol	2.1	3.5	8.0	-2.7	-0.8	-1.6	-0.5	1.0	1.9	-0.4	0.0	-2.3	-1.8	-2.3	-2.3	-2.8	-2.8	-1.0	-2.0	-2.0
Headache pain in last month	0.5	0.8	1.6	1.0	-1.0	-0.9	0.0	-0.5	1.2	-0.3	-0.7	0.0	-1.1	-1.2	-1.0	-0.7	-0.3	-1.1	-0.9	-1.3
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	9.2	-3.0	-1.0	-1.5	-1.9	-1.4	1.2	-1.4	0.0	-1.0	-1.2	-0.9	-0.9	-1.6	-1.5	-0.0	-1.0	-0.9
Glaucoma (self-reported)	0.4	0.5	2.7	0.2	-0.8	-0.5	-0.5	-1.6	0.5	1.2	-0.7	0.9	-0.4	0.2	0.7	0.3	0.5	0.6	0.2	-0.5
Gout (self-reported)	0.8	1.0	5.3	1.6	-0.1	-0.5	-0.6	-1.9	-0.3	0.1	-2.3	0.8	0.7	0.7	0.8	1.2	1.3	-0.3	-0.2	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.6	-0.9	1.2	0.7	0.1	0.5	-1.3	0.9	-0.1	-0.9	1.0	0.1	-0.3	-0.1	-0.2	-0.3	-0.1	0.9
Medication: Amlodipine	1.1	1.6	4.2	1.2	-1.5	-1.8	-2.0	-1.5	-0.1	-1.3	-1.2	1.3	0.8	0.7	1.1	1.5	1.9	-0.5	-0.2	-0.2
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.6	1.6	0.5	0.5	0.3	0.8	-1.5	-0.8	0.0	0.9	1.4	1.1	1.1	1.1	1.0	0.2	1.4	0.9
Birth weight	1.1	2.4	6.6	-1.5	-0.3	-0.4	-1.5	1.2	1.6	-1.5	-0.0	-1.5	-1.7	-1.8	-2.0	-2.6	-2.4	-1.3	-1.6	-1.4
Chronic bronchitis/emphysema (mother)	1.6	1.8	6.5	-0.2	1.1	2.0	1.5	0.7	0.5	-1.1	2.5	-1.7	-1.1	-1.1	-1.6	-1.8	-1.9	-0.2	-0.3	-0.3
High blood pressure (siblings)	0.5	0.7	3.3	1.4	-0.5	-0.5	-0.6	-0.6	-0.4	-1.1	-0.3	1.8	0.2	0.7	1.2	0.5	0.6	0.4	1.2	-0.1
Forced vital capacity (FVC), Best measure	0.7	2.4	6.8	-2.3	-1.5	-0.7	-1.1	0.2	2.1	0.3	1.3	-0.7	-2.6	-1.5	-1.1	-1.9	-2.1	1.0	-1.1	-2.0
Body fat percentage	0.8	3.0	6.8	-0.4	-0.5	-0.2	0.5	0.9	1.5	-0.5	0.3	-2.6	-2.2	-2.4	-2.6	-2.6	-2.5	-2.0	-1.7	-1.6
Leg fat percentage (right)	1.0	3.5	9.6	-0.4	-1.1	-0.8	0.2	0.4	1.8	-1.0	-0.1	-2.4	-2.5	-2.7	-2.8	-2.0	-1.7	-3.1	-2.3	-2.1
Arm fat-free mass (right)	0.7	3.5	10.1	-1.0	1.3	2.2	1.8	2.1	1.0	1.3	2.6	-1.9	-2.0	-1.7	-2.2	-2.9	-3.2	-0.1	-0.8	-0.7
Exposure to tobacco smoke outside home	0.5	0.7	3.6	-0.3	0.8	0.3	0.3	-0.4	-0.1	0.2	1.0	-1.9	-0.3	-0.3	-0.7	-1.5	-1.7	0.3	0.1	0.4
Comparative body size at age 10	0.4	1.2	4.0	-0.1	1.4	1.0	0.5	0.2	-1.3	-2.0	2.0	-0.5	0.3	0.5	0.0	-1.3	-1.4	1.1	1.0	1.1
Number of full brothers	0.2	0.2	1.8	-0.5	0.4	-0.3	-0.4	1.3	-0.1	0.4	-0.5	0.5	0.2	0.3	0.2	0.1	0.0	0.4	0.2	0.2
Worry too long after embarrassment	0.4	0.6	3.6	-0.5	0.9	-0.2	0.2	1.9	-0.3	-1.0	0.1	1.1	0.8	0.4	0.6	-0.2	-0.3	1.2	0.6	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.4	2.1	0.7	0.8	0.3	0.2	-0.9	0.5	-0.7	1.9	2.0	1.6	1.8	1.5	1.6	1.2	1.5	1.2
Wheeze or whistling in the chest in last year	1.0	1.8	8.4	1.2	1.4	1.5	2.5	1.1	-0.9	-2.4	2.9	-0.9	0.5	0.0	-0.3	-0.3	-0.6	0.0	0.4	0.7
Number of children fathered	0.6	0.7	3.0	0.5	-1.2	-0.1	-0.4	-0.6	1.1	1.7	-1.2	0.4	-0.1	-0.2	-0.1	0.7	0.9	-1.0	-1.1	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.4	0.8	0.1	-0.1	0.2	-0.8	-0.1	1.2	-0.4	0.0	0.7	0.8	0.9	0.5	0.4	1.1	0.5	0.4
Age at first live birth	0.6	1.1	2.7	1.1	0.9	0.7	0.3	0.8	-1.3	-0.9	0.3	1.1	1.0	1.1	1.1	1.6	1.4	1.1	1.0	1.2
Pulse wave peak to peak time	1.5	1.8	4.9	-0.9	1.8	0.2	1.2	1.6	-1.5	0.4	1.4	0.2	1.4	1.3	0.9	0.3	-0.2	2.2	2.2	1.9
Health satisfaction	3.1	4.0	9.7	-0.3	-2.1	-0.7	-0.3	-0.2	2.4	0.1	-0.5	-2.1	-2.4	-2.7	-2.6	-2.1	-1.7	-2.8	-3.1	-2.7
Shortness of breath walking on level ground	1.6	1.9	4.4	-0.3	-1.1	-1.2	-0.3	-0.4	1.2	-1.1	-0.6	-2.1	-1.5	-2.0	-2.0	-1.6	-1.5	-1.7	-1.5	-1.6
Qualifications: College or University degree	0.6	1.8	3.7	0.5	0.8	-0.0	-0.5	1.6	-1.4	0.3	-1.4	1.9	1.5	1.8	1.7	1.5	1.5	1.8	1.3	1.4
Eye problems/disorders: None of the above	0.6	0.6	3.6	0.3	-1.0	-0.6	-1.0	-0.6	0.7	0.4	-1.9	0.7	-0.2	-0.2	0.1	0.5	0.8	-1.2	-0.8	-0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.2	-0.4	0.9	-0.0	1.0	0.2	0.3	-1.1	0.7	0.2	-0.9	-0.6	-0.6	-1.4	-1.5	0.4	-0.2	-0.4
Emphysema/chronic bronchitis	0.8	0.9	2.1	1.2	-0.1	-0.6	0.1	-0.7	-0.5	-0.9	-0.0	1.3	1.3	1.3	1.5	1.2	1.1	0.9	0.8	0.4
Medication for pain relief, constipation, heartburn	0.8	1.3	2.8	1.3	0.3	0.2	-0.6	-1.3	-1.3	0.0	-0.1	1.2	1.3	1.7	1.7	1.5	1.4	0.8	1.2	1.5
Neck or shoulder pain in last month	0.5	0.7	2.1	0.1	0.1	-0.1	0.3	1.0	0.5	0.8	-0.7	-0.5	-1.1	-0.9	-0.9	-1.4	-1.4	-1.0	-0.6	-0.7
Medication: Blood pressure	1.7	3.0	12.1	3.5	1.1	1.3	2.1	1.7	-1.8	1.3	-0.7	2.4	1.5	1.6	1.8	1.9	1.8	0.1	1.4	1.3
Angina (self-reported)	2.6	3.4	7.9	0.7	2.0	1.6	0.7	1.5	-2.3	0.5	-0.4	1.8	2.8	2.1	2.0	2.5	2.3	1.5	2.1	2.1
Migraine (self-reported)	0.5	0.6	3.2	-0.1	-0.4	-1.3	-0.4	0.7	0.4	1.7	-1.8	0.0	0.2	-0.3	-0.1	0.4	0.4	-0.2	-0.4	-0.5
Medication: Ibuprofen	2.9	3.4	7.3	-0.4	-1.5	-1.7	0.5	-0.7	1.7	-0.6	-0.4	-1.5	-2.7	-2.5	-2.6	-2.6	-2.3	-2.5	-1.8	-2.2
Medication: Allopurinol	1.6	2.1	7.5	2.7	0.9	0.6	0.4	-1.6	-1.6	0.4	-1.4	1.3	1.8	1.8	1.7	1.6	1.5	0.5	1.2	1.6
Medication: Omeprazole	0.7	0.8	1.9	0.6	1.1	1.2	0.7	0.9	-1.0	-0.9	0.7	0.5	1.1	0.8	0.7	1.0	1.0	0.6	1.4	0.9
Medication: Seretide 50 evohaler	2.4	2.8	7.4	0.7	2.3	0.7	1.3	0.3	-2.5	-0.4	0.8	0.2	2.1	2.1	1.6	0.3	-0.2	2.7	2.7	2.4
Mean time to correctly identify matches	0.8	1.5	8.2	-0.9	-1.2	-1.1	-2.3	-1.2	0.9	-2.9	0.7	-0.4	-1.5	-1.0	-0.5	-0.4	-0.4	0.3	-0.4	-1.5
Heart disease (mother)	0.4	0.5	3.1	1.2	-0.1	0.1	-0.3	1.8	0.2	0.2	-0.6	0.6	0.6	0.4	0.6	0.9	0.9	0.0	-0.3	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.7	1.6	0.5	0.9	1.6	0.8	-0.1	0.2	-0.3	0.7	0.3	0.2	0.2	-0.1	-0.1	0.8	0.7	0.2
Whole body fat mass	0.9	3.9	10.4	-0.9	-0.3	0.2	0.5	1.4	1.9	-0.1	0.6	-2.7	-2.6	-2.6	-2.9	-3.2	-3.2	-1.8	-1.9	-1.8
Leg fat mass (right)	1.1	4.4	9.7	-0.9	-0.5	-0.1	0.5	1.3	2.1	-0.3	0.4	-2.7	-2.8	-2.9	-3.1	-3.1	-3.0	-2.4	-2.4	-2.1
Arm predicted mass (right)	0.7	3.5	10.3	-1.3	1.0	2.0	1.3	1.9	1.3	1.4	2.3	-1.9	-2.1	-1.9	-2.3	-3.0	-3.2	-0.4	-1.2	-0.9
Pulse rate, automated reading	0.7	2.4	5.1	-1.1	-1.1	-1.9	-0.6	-1.1	1.1	-0.3	0.1	-2.0	-1.7	-1.8	-1.8	-2.3	-2.1	-1.9	-1.7	-1.4
Alcohol intake frequency.	0.2	0.4	1.4	-0.7	0.2	-0.3	0.6	1.2	-0.5	-1.1	0.8	0.1	-0.5	-0.0	0.0	-1.0	-0.9	0.3	0.9	-0.1
Comparative height size at age 10	0.7	3.6	10.4	-2.0	0.0	0.9	-0.0	0.8	1.7	-1.2	3.2	-3.0	-2.0	-2.1	-2.5	-2.5	-2.8	0.4	-1.4	-1.2
Number of full sisters	0.5	0.7	3.5	-0.4	0.6	0.7	0.3	1.9	0.5	-0.0	0.3	-0.5	-0.8	-0.7	-0.8	-1.3	-1.3	-0.1	-0.7	-0.4
Suffer from ‘nerves’	0.3	0.5	4.5	0.2	0.2	-0.4	-0.1	-0.8	-0.4	-0.1	0.1	1.0	0.6	0.8	1.0	0.4	0.2	2.1	0.8	0.2
Overall health rating	3.5	7.6	15.5	-0.4	-1.1	-0.9	0.9	-0.1	3.0	-2.3	0.4	-3.1	-3.8	-3.9	-3.9	-3.8	-3.4	-3.6	-2.7	-3.2
Chest pain or discomfort	0.3	0.5	2.2	0.6	0.2	-0.1	1.5	0.2	0.3	-1.1	1.3	-0.5	-0.3	-0.8	-0.8	-0.2	-0.3	-0.3	-0.2	-0.6
Had major operations	0.7	0.9	3.7	1.1	0.8	0.3	0.2	1.9	-0.5	1.5	-1.5	0.6	1.2	0.3	0.3	0.8	0.9	-0.6	0.2	0.6
Age at last live birth	0.6	0.8	2.6	0.2	0.8	0.3	-0.2	-0.2	-1.3	-0.5	0.3	0.9	0.9	0.9	0.9	1.6	1.4	0.9	1.0	1.1
Family relationship satisfaction	1.0	1.3	3.0	-1.7	0.4	-0.6	-0.8	1.2	0.4	-1.5	1.0	-1.7	-0.9	-1.1	-1.5	-1.4	-1.5	-0.1	-1.0	-0.4
Leg pain on walking	5.9	7.4	14.6	-2.0	-1.8	-2.1	-1.2	0.3	3.0	-1.4	-0.2	-3.6	-3.5	-3.6	-3.6	-3.8	-3.5	-2.2	-3.1	-3.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.2	1.0	0.3	-0.0	0.7	-1.5	-0.2	1.8	-0.6	0.6	0.3	0.9	0.9	0.4	0.3	0.4	0.4	0.6
Commuting to job workplace: Car/motor vehicle	1.5	1.7	4.2	-0.2	-0.9	-0.8	-0.1	0.8	1.4	-1.1	-0.0	-0.8	-1.9	-1.5	-1.5	-1.9	-1.7	-2.1	-1.2	-1.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.8	0.2	-0.2	0.3	-0.2	-0.2	0.6	-1.7	0.8	-0.3	-0.4	-0.4	-0.4	-0.4	-0.3	-0.4	-0.9	-0.5
Medication: Aspirin	0.5	0.7	2.1	0.5	0.5	0.6	-0.1	-0.2	-0.9	0.2	-0.1	0.9	1.1	1.0	1.0	1.5	1.3	1.0	0.8	0.7
Supplements: Vitamin C	5.4	6.3	12.8	-2.4	-0.5	-0.7	0.2	2.4	2.4	-3.6	2.8	-3.6	-2.5	-3.1	-3.5	-3.2	-3.1	-1.8	-1.8	-1.6
Knee pain experienced in last month	7.0	10.9	22.0	-0.8	-2.7	-1.0	-0.8	0.7	4.0	-2.4	0.6	-4.1	-4.2	-4.7	-4.6	-3.8	-3.3	-4.2	-4.0	-4.1
Hypertension (Self-reported)	1.9	5.2	20.5	4.5	0.5	-0.0	0.8	-0.4	-2.4	0.6	-1.9	3.3	2.5	2.7	3.0	2.7	2.8	0.6	2.2	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	2.4	1.0	1.2	0.9	1.3	0.9	-1.5	0.3	0.7	0.6	0.9	1.5	1.2	0.4	0.1	1.5	0.9	1.5
Illnesses of father: Heart disease	0.6	0.9	4.3	-1.3	0.8	2.1	0.1	1.1	-0.0	0.4	1.8	-1.2	0.1	-0.6	-1.0	-0.5	-0.6	0.1	-0.0	-0.0
Illnesses of siblings: Diabetes	1.4	1.8	7.0	2.6	1.3	1.3	1.4	-0.1	-1.3	0.1	0.6	0.9	1.4	1.4	1.2	0.7	0.7	1.6	1.9	1.4
Smoking status: Previous	0.6	0.9	4.6	-2.1	-0.7	-1.7	-1.6	0.0	1.3	0.6	-0.9	0.3	-0.1	-0.0	0.4	-0.6	-0.5	0.7	-0.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.0	0.6	0.9	0.8	1.4	0.5	-0.8	0.8	0.8	-0.4	-0.1	-0.3	-0.6	-0.2	-0.3	0.2	0.4	0.4
Whole body fat-free mass	0.6	3.2	10.5	-1.2	1.3	2.2	1.3	2.0	1.1	1.3	2.2	-1.8	-1.8	-1.5	-2.0	-3.0	-3.2	0.2	-0.9	-0.6
Leg fat-free mass (right)	0.7	3.5	12.3	-0.8	1.9	2.3	1.7	2.6	0.6	1.2	2.1	-1.9	-1.5	-1.2	-1.9	-3.2	-3.5	0.3	-0.5	-0.2
Arm fat percentage (left)	0.3	1.4	4.9	0.5	0.3	0.2	1.0	0.9	0.5	-0.3	-0.0	-1.8	-1.3	-1.2	-1.5	-2.2	-2.2	-1.1	-0.6	-0.6
Average weekly red wine intake	1.1	1.6	3.2	0.9	1.1	1.1	1.0	0.5	-1.7	1.7	0.6	1.0	1.3	1.6	1.4	1.0	0.7	1.3	1.6	1.8
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.0	-0.9	-1.0	-0.6	-1.0	0.7	0.5	0.2	0.4	-0.4	0.2	0.1	0.2	-0.1	0.0	-0.5	-0.9	-0.3
Mood swings	1.1	2.1	4.2	-1.6	0.1	0.2	0.5	1.8	1.8	0.1	0.5	-1.3	-1.6	-2.0	-2.1	-1.9	-1.6	-1.2	-1.6	-1.6
Loneliness, isolation	0.3	0.5	1.6	0.6	0.7	0.1	0.8	0.6	-0.2	-1.1	0.1	-0.6	-0.6	-0.9	-1.3	-0.8	-0.8	-0.7	-0.2	-0.0
Long-standing illness, disability or infirmity	1.5	2.2	6.4	0.8	-1.3	0.4	0.2	1.4	2.0	-0.8	-0.2	-0.8	-2.4	-2.2	-1.8	-1.3	-1.0	-1.7	-1.4	-2.5
Ever had bowel cancer screening	1.5	1.7	3.4	-0.9	-1.4	-0.5	-0.9	1.0	1.4	-1.9	-0.0	-1.4	-1.5	-1.8	-1.6	-1.6	-1.5	-0.8	-0.8	-1.6
Diabetes diagnosed by doctor	0.4	0.7	4.4	0.5	0.8	0.5	0.3	2.1	-0.9	0.3	-1.2	0.9	0.8	0.9	0.9	0.6	0.6	0.2	0.8	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	-0.2	0.4	0.1	-0.6	0.7	-0.1	-0.4	-0.0	0.4	0.1	0.2	0.2	0.0	0.0	0.2	0.1	0.1
Friendships satisfaction	0.3	0.3	1.4	-0.6	0.6	0.0	0.2	-0.2	0.2	0.1	0.5	-0.4	-0.7	-0.6	-0.8	-1.1	-1.2	-0.1	-0.6	-0.1
Qualifications: nursing, teaching	0.4	0.6	3.9	-1.3	-0.7	-1.2	-2.0	-1.0	0.5	-0.7	-0.5	0.3	0.3	0.2	0.4	0.4	0.5	0.4	-0.6	-0.3
Commuting to job workplace: Walk	0.5	0.5	5.0	-2.2	-0.1	0.3	-0.2	-0.8	0.4	0.2	1.0	0.0	-0.4	-0.5	-0.2	-0.8	-0.7	0.3	0.0	-0.7
Eye problems/disorders: Cataract	0.1	0.1	0.4	-0.0	0.6	0.1	0.4	-0.1	-0.4	0.1	0.6	-0.7	0.1	-0.0	-0.3	-0.5	-0.6	0.1	0.2	0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.9	0.6	-0.2	-0.8	-0.1	0.0	-0.7	1.4	-1.3	1.4	0.6	0.5	0.8	0.3	0.4	-0.3	0.9	0.2
Medication for cholesterol	1.1	1.6	7.5	0.8	1.9	2.7	1.9	0.7	-0.5	0.6	2.6	-0.8	-0.2	0.1	-0.4	-0.8	-1.1	0.5	0.6	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.2	4.2	0.3	1.4	1.0	0.5	0.7	-1.0	1.4	-0.9	1.4	0.9	1.2	1.2	-0.3	-0.5	2.1	1.5	1.0
Back pain experienced in last month	1.0	1.5	5.2	0.3	-0.0	-0.4	0.9	0.3	0.9	-1.3	0.8	-0.9	-1.8	-1.6	-1.5	-2.2	-2.3	-0.6	-0.7	-1.0
Mineral and other dietary supplements	1.3	1.8	5.2	1.6	0.0	-1.5	0.1	-2.3	-1.0	2.3	-2.1	1.4	0.7	1.6	1.6	0.5	0.4	0.7	0.3	1.1
Breast cancer (self-reported)	0.4	0.5	1.9	-0.4	1.1	0.4	0.1	1.4	-0.9	-1.0	0.1	0.5	-0.1	0.6	0.5	-0.8	-1.2	0.1	0.6	0.7
Asthma (self-reported)	1.1	2.2	8.5	2.9	0.8	1.0	1.8	0.9	-1.3	-1.0	0.7	1.8	1.8	1.4	1.6	1.5	1.4	1.0	1.6	1.1
Osteoporosis (self-reported)	0.3	0.4	3.4	-0.4	0.5	0.1	-0.2	1.9	-0.3	-0.3	-0.1	-0.0	0.0	-0.0	-0.1	-0.6	-0.6	0.1	1.0	0.0
Osteoarthritis (self-reported)	3.1	4.0	8.8	-1.3	-2.0	-1.3	-1.2	-0.4	2.3	-2.4	-0.1	-1.7	-3.0	-2.9	-2.6	-1.9	-1.7	-1.6	-2.1	-2.9
Medication: Aspirin	0.8	1.0	1.8	0.7	0.9	0.7	0.3	-0.2	-1.3	0.4	-0.2	1.0	1.3	1.2	1.2	1.4	1.2	1.4	1.2	1.0
Medication: Gliclazide	3.2	3.6	7.5	2.1	2.2	2.3	1.6	1.6	-2.6	1.1	0.4	1.2	2.0	2.3	2.1	1.0	0.7	1.6	2.7	2.6
Illnesses of father: None of the above (group 1)	0.4	0.5	3.5	0.2	-0.9	-1.9	-0.5	-0.8	0.2	0.2	-1.0	0.6	-0.4	0.2	0.4	0.6	0.6	-0.3	-0.5	-0.3
Smoking status: Current	1.0	1.5	3.5	-0.7	-0.1	0.3	0.8	0.0	1.7	0.6	0.4	-1.9	-1.3	-1.8	-1.9	-1.8	-1.8	-0.1	-1.1	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.2	5.1	-1.0	-1.5	-1.2	-2.3	-0.8	1.2	-0.3	-1.3	0.4	-1.3	-0.7	-0.3	-0.5	-0.4	-0.7	-1.1	-1.2
Whole body water mass	0.6	3.2	10.4	-1.3	1.2	2.1	1.2	1.8	1.2	1.3	2.2	-1.8	-1.8	-1.6	-2.0	-3.0	-3.2	0.2	-1.0	-0.7
Leg predicted mass (right)	0.6	3.4	12.1	-0.8	1.9	2.3	1.7	2.5	0.6	1.2	2.0	-1.8	-1.5	-1.2	-1.8	-3.2	-3.5	0.3	-0.5	-0.2
Arm fat mass (left)	0.6	2.3	8.6	-0.2	0.5	0.8	1.0	1.3	1.0	-0.1	0.7	-1.9	-1.8	-1.7	-2.0	-2.9	-2.9	-1.0	-1.0	-0.9
Number of self-reported non-cancer illnesses	0.4	0.7	5.7	2.4	-0.6	0.2	0.1	1.4	-0.1	-0.1	-1.1	0.7	0.1	-0.1	0.3	0.7	0.8	-0.3	0.1	-0.5
Average weekly champagne plus white wine intake	1.0	1.4	3.7	0.6	0.4	0.7	-0.0	-1.3	-1.9	0.3	-0.0	0.2	1.8	1.6	1.3	1.3	1.1	1.7	1.1	1.8
Miserableness	0.2	0.4	1.5	0.4	1.0	-0.0	0.8	0.7	0.1	-0.2	-0.1	-0.4	-0.3	-0.6	-0.7	-1.2	-1.2	0.4	0.2	-0.2
Guilty feelings	0.3	0.4	1.6	1.1	-0.3	0.1	0.6	0.9	0.9	-1.3	0.3	0.3	-0.9	-0.4	-0.1	-0.4	-0.3	0.7	-0.0	-0.8
Wears glasses or contact lenses	0.5	0.6	2.7	0.9	-0.6	0.3	-0.1	-0.5	-0.1	-0.7	-0.7	1.6	0.4	0.4	0.7	1.1	1.3	-0.4	0.7	-0.1
Ever taken oral contraceptive pill	1.2	1.3	5.7	-0.6	1.8	0.8	2.4	0.7	-1.2	1.2	2.0	-0.7	0.3	0.6	0.0	-0.2	-0.7	0.6	0.9	1.4
Hearing aid user	1.8	2.0	3.7	-1.4	-0.7	0.3	-0.6	0.4	1.7	1.1	-0.6	-1.5	-1.8	-1.9	-1.8	-1.7	-1.5	-1.7	-1.9	-1.7
Mother’s age at death	0.7	0.9	2.3	-1.4	0.5	0.2	-0.8	0.1	-0.7	1.4	-0.2	1.2	0.8	0.9	1.1	1.2	0.9	1.5	0.7	0.8
Financial situation satisfaction	0.4	0.5	1.8	-0.8	1.3	0.4	1.0	0.3	-0.6	0.5	0.3	-0.6	0.0	-0.0	-0.3	-0.9	-1.2	-0.2	0.1	0.7
Tinnitus: Yes, now most or all of the time	1.2	1.4	4.8	-2.2	-1.7	-1.0	-2.1	0.2	1.7	0.8	-0.4	0.4	-0.2	-0.5	0.0	0.6	0.9	-0.7	-1.6	-1.3
Commuting to job workplace: Public transport	0.2	0.2	0.7	0.2	-0.4	0.1	-0.4	-0.8	-0.2	-0.5	-0.0	0.8	0.2	0.4	0.5	0.6	0.6	0.7	0.1	-0.1
Eye problems/disorders: Glaucoma	0.3	0.3	2.6	0.4	-0.5	-0.1	-0.1	-0.9	0.5	1.6	-0.2	0.7	-0.4	-0.0	0.3	0.4	0.5	0.3	0.1	-0.4
Medication: Blood pressure	1.0	2.0	5.8	0.6	-1.0	-1.0	-1.8	-0.8	-0.5	-0.2	-2.3	2.4	1.2	1.3	1.9	2.0	2.3	0.6	0.5	0.1
Pain type(s) experienced in last month: Hip pain	3.1	3.8	7.5	-2.0	-0.9	-1.7	-1.4	1.9	1.9	-1.0	-0.8	-2.2	-2.1	-2.5	-2.5	-2.7	-2.6	-1.7	-2.3	-1.9
Supplements: Fish oil (including cod liver oil)	0.8	1.0	5.1	-0.9	0.1	1.4	0.4	1.3	0.3	-1.8	2.2	-0.8	-0.5	-1.1	-1.1	-0.3	-0.3	-0.5	0.3	-0.4
High cholesterol (Self-reported)	0.6	1.1	3.0	1.7	0.5	1.0	0.9	-0.6	-1.1	1.4	-0.2	-0.2	1.5	0.8	0.6	1.7	1.6	-0.2	0.7	1.2
Medication: Bendroflumethiazide	0.9	1.4	3.7	1.4	0.5	0.2	0.3	1.3	-1.1	0.3	-0.7	1.8	1.2	1.6	1.9	1.2	1.1	1.0	1.2	1.0
Medication: Paracetamol	1.8	2.8	8.2	-1.6	-0.8	-1.7	-0.2	0.7	1.8	-0.4	-0.4	-1.8	-1.8	-2.0	-1.8	-2.9	-2.7	-1.0	-1.8	-2.0
Medication: Lisinopril	1.0	1.3	4.0	1.1	0.3	0.2	0.0	0.1	-0.9	1.2	-1.3	1.8	1.1	1.7	2.0	1.1	1.1	1.1	1.0	0.7
Medication: Atorvastatin	0.4	0.5	2.1	1.2	0.3	1.5	1.2	0.1	0.0	0.9	0.8	-0.3	-0.6	-0.7	-0.9	-0.2	-0.2	-0.7	-0.0	0.0
Illnesses of father: High blood pressure	0.6	0.7	4.3	0.1	0.6	0.4	-0.2	1.0	-0.8	2.1	-1.6	0.7	1.0	0.7	0.5	0.2	0.3	-0.3	0.7	0.8
Alcohol drinker status: Never	1.1	1.3	3.0	-1.1	-0.6	0.2	0.4	1.2	0.9	-1.5	1.2	-1.3	-1.6	-1.5	-1.7	-1.2	-1.1	-0.5	-1.0	-1.1
Ever smoked	0.8	1.4	7.4	-2.7	-0.3	-1.8	-0.9	0.7	1.4	1.2	-0.5	-0.4	-0.6	-0.6	-0.2	-1.4	-1.5	1.5	-0.5	-1.1
Basal metabolic rate	0.7	3.6	12.1	-1.3	1.0	1.9	1.1	1.9	1.4	1.0	2.1	-2.1	-2.1	-1.9	-2.3	-3.3	-3.5	-0.2	-1.2	-1.0
Leg fat percentage (left)	0.8	2.8	7.1	-0.2	-0.2	-0.1	1.1	1.1	1.1	-0.7	0.4	-2.4	-2.1	-2.3	-2.6	-2.2	-2.0	-2.7	-1.6	-1.3
Arm fat-free mass (left)	0.7	3.6	10.2	-1.4	0.7	1.7	0.9	1.5	1.7	1.1	1.9	-2.0	-2.3	-2.1	-2.5	-3.1	-3.2	-0.7	-1.6	-1.2
Number of operations (self-reported)	0.8	1.2	6.1	0.5	-0.7	-0.4	-1.1	1.0	0.8	2.5	-2.5	0.2	-0.4	-0.7	-0.4	-0.2	0.1	-1.6	-0.9	-1.0
Average weekly beer plus cider intake	0.6	0.8	2.6	0.7	1.2	1.3	1.3	1.6	-0.4	1.3	1.3	-0.9	0.5	-0.1	-0.4	0.2	0.0	0.7	0.4	0.6
Irritability	0.1	0.2	0.5	-0.7	-0.7	0.1	0.2	-0.2	0.7	0.2	0.6	-0.0	-0.4	-0.4	-0.1	0.2	0.3	-0.2	-0.3	-0.6
Risk taking	1.3	1.9	4.6	0.2	0.9	0.6	0.8	1.2	-1.1	1.5	-0.0	1.1	2.2	1.9	1.8	1.9	1.7	1.5	0.9	1.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	4.7	1.0	1.1	1.1	0.5	2.2	-0.3	-0.2	-0.1	0.8	0.0	0.1	-0.2	0.5	0.5	0.0	0.2	0.4
Fractured/broken bones in last 5 years	3.0	3.9	13.3	3.6	1.2	-0.3	1.3	-1.0	-2.3	1.7	-1.2	1.9	2.1	2.7	2.6	1.8	1.4	1.7	2.0	2.3
Age started oral contraceptive pill	1.2	1.5	4.2	0.3	2.1	1.8	0.7	0.5	-1.7	-0.3	1.3	-0.2	1.2	1.4	1.0	0.0	-0.3	0.9	1.7	1.9
Diastolic blood pressure, automated reading	0.4	1.4	4.5	1.1	-1.6	-1.9	-0.7	-2.1	0.1	1.1	-2.0	0.7	0.5	0.6	0.7	1.1	1.3	-1.0	-0.7	-0.0
Ever depressed for a whole week	0.9	1.1	2.7	-1.3	0.0	0.3	0.6	0.3	1.0	-0.5	1.4	-1.2	-1.3	-1.3	-1.4	-1.6	-1.6	-0.2	-0.4	-0.7
Unable to work because of sickness or disability	1.0	1.3	6.8	1.4	1.5	1.8	2.6	1.1	-0.9	1.3	0.4	-0.1	0.2	0.2	-0.1	-0.3	-0.5	0.4	1.4	0.8
Commuting to job workplace: Cycle	0.3	0.4	1.6	-1.3	0.3	0.2	0.1	0.8	0.3	0.5	0.4	-0.5	-0.7	-0.5	-0.6	-0.6	-0.6	1.2	0.3	-0.5
Myopia	0.1	0.2	1.1	-0.2	-0.2	0.7	0.9	0.4	-0.3	-0.1	1.1	0.6	0.0	0.2	0.3	0.2	0.3	-0.0	0.5	-0.1
Vascular/heart problems diagnosed by doctor	1.9	5.2	16.3	-4.0	-0.9	-0.4	-1.1	0.1	2.4	-0.6	1.3	-3.5	-2.6	-2.6	-2.8	-3.0	-3.1	-1.2	-2.3	-1.9
Cholesterol lowering medication	0.4	0.6	2.4	-0.6	-0.8	-1.0	-1.6	-1.3	0.4	-1.1	-0.9	-0.4	0.6	0.0	0.2	0.6	0.6	0.2	-0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	5.9	1.2	1.7	2.4	1.6	1.3	-1.4	-0.2	1.2	1.0	1.6	1.4	1.2	1.1	1.1	1.4	2.0	1.5
Pain experienced in last month	5.0	8.4	16.0	0.2	2.3	1.8	0.8	-0.7	-3.6	0.6	0.2	2.7	3.9	4.0	3.9	3.8	3.3	3.8	3.7	3.5
Supplements: Calcium	0.4	0.5	2.2	-1.4	-0.2	0.6	-0.5	0.8	0.0	-1.5	0.6	0.0	0.3	-0.4	-0.2	0.9	1.0	-0.3	0.4	-0.3
Basal cell carcinoma (self-reported)	1.3	1.5	3.9	-2.0	0.9	1.5	-0.1	0.8	0.7	0.5	1.5	-1.9	-1.3	-1.4	-1.7	-1.3	-1.4	-0.1	-0.9	-0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.4	-1.1	-0.2	-0.6	-1.2	-1.1	0.2	-0.9	-0.3	0.6	0.5	0.2	0.3	0.8	0.9	0.7	-0.1	-0.2
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	6.0	1.5	0.9	0.3	-1.1	-0.3	-2.1	0.6	-1.4	1.2	2.5	2.3	2.2	2.3	2.2	1.2	1.3	2.1
Heart disease (siblings)	0.9	1.1	2.6	0.0	0.6	0.8	0.5	-1.3	-1.4	1.1	-0.6	1.4	1.1	1.3	1.5	0.2	0.1	1.4	1.6	0.9
Alcohol drinker status: Previous	0.7	0.7	2.7	-1.6	-0.9	-1.2	-0.6	-0.7	0.4	-1.5	0.9	-0.8	-0.4	-0.2	-0.0	-1.1	-1.2	0.1	0.2	-0.5
Pack years of smoking	1.2	1.8	5.4	-1.2	-0.9	-0.5	-0.2	-1.9	1.5	-0.8	1.2	-1.6	-1.7	-1.2	-1.1	-2.3	-2.3	-0.7	-0.5	-1.3
Impedance of whole body	0.8	4.3	13.1	-1.6	-3.6	-2.8	-2.7	-2.8	2.4	-1.3	-0.4	-1.9	-1.6	-2.1	-1.6	0.1	0.4	-1.1	-2.3	-2.6
Leg fat mass (left)	1.0	3.8	9.7	-0.8	0.2	0.6	1.1	1.7	1.5	-0.2	0.8	-2.7	-2.4	-2.5	-2.9	-3.1	-3.1	-2.0	-1.8	-1.5
Arm predicted mass (left)	0.8	3.9	10.7	-1.5	0.9	1.9	1.2	1.6	1.7	1.0	2.2	-2.1	-2.4	-2.2	-2.6	-3.1	-3.3	-0.6	-1.6	-1.2