[Hub]/) : Traits : Systolic Blood Pressure :

chr2:41,877,732-44,242,779

Best TWAS P=9.94e-14 · Best GWAS P=7.76e-15 conditioned to 0.000202

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Putamen basal ganglia HAAO 0.18 0.28 lasso 2 0.25 1.2e-06 4.86 -5.4 7.2e-08 0.03 0.21 0.19 FALSE
2 GTEx Colon Sigmoid HAAO 0.19 0.02 enet 23 0.06 4.5e-03 -4.97 -6.3 2.9e-10 0.03 0.26 0.04 TRUE
3 GTEx Nerve Tibial OXER1 0.31 0.03 lasso 8 0.05 3.5e-04 5.28 -5.4 7.2e-08 -0.02 0.26 0.67 FALSE
4 GTEx Spleen FTOP1 0.27 -0.01 lasso 13 0.01 2.2e-01 4.23 7.4 9.9e-14 -0.01 0.09 0.11 TRUE
5 GTEx Stomach AC010883.5 0.16 0.07 lasso 6 0.07 2.4e-04 5.57 -5.3 9.1e-08 0.45 0.28 0.17 TRUE
6 GTEx Vagina ZFP36L2 0.32 0.08 enet 27 0.14 4.7e-04 -7.21 5.5 4.7e-08 -0.44 0.05 0.39 FALSE
7 NTR Blood COX7A2L 0.02 0.00 blup 513 0.01 5.2e-03 -2.02 5.8 7.5e-09 0.01 0.06 0.02 FALSE
8 ROSMAP Brain Pre-frontal Cortex KCNG3 0.08 0.01 bslmm 506 0.02 4.6e-04 -0.94 -5.3 1.3e-07 -0.02 0.12 0.08 TRUE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HAAO 0.04 0.05 lasso 4 0.05 2.7e-06 4.65 -5.1 3.1e-07 0.01 0.09 0.90 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PLEKHH2 0.07 0.00 blup 127 0.03 3.2e-04 -3.31 -6.6 3.8e-11 0.35 0.12 0.13 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma PLEKHH2 0.09 0.01 blup 127 0.05 1.1e-05 1.75 -5.4 7.0e-08 0.08 0.05 0.21 FALSE