Hub : Genes

KCNG3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 ROSMAP Brain Pre-frontal Cortex 0.0767 0.0360 0.0034 0.01 0.020 0.002 0.023 0.004 1.6e-02 0.0011 1.9e-01 0.00046 9.2e-02
2 TCGA Breast Invasive Carcinoma 0.0349 0.0181 0.0018 0.02 0.016 0.019 NA 0.020 4.9e-05 0.0002 5.6e-05 NA 4.8e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.0 0.1 0.1 0.0 -0.4
Bipolar Disorder or Schizophrenia 0.7 1.8 2.2 -1.5 -1.2
Depressed Affect (Nagel 2018) 0.4 0.9 1.2 -0.8 1.1
Depression (Nagel 2018) 1.0 1.4 2.0 -0.9 1.4
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.5 0.7 -0.3
Neuroticism (Nagel 2018) 0.7 1.6 1.7 -1.3 1.2
Schizophrenia (2018) 1.3 2.7 3.8 -2.0 -1.3
Schizophrenia vs Biploar Disorder 5.0 6.6 8.2 -2.9 2.2
Worry (Nagel 2018) 0.3 0.6 1.1 -0.3 1.0
Alzheimer’s Disease (in mother) 0.8 1.0 1.5 -0.7 1.2
Alzheimer’s Disease (in father) 0.2 0.2 0.5 0.1 -0.7
Alzheimer’s Disease (including proxy) 0.3 0.5 0.8 0.4 -0.9
Crohns Disease (2017) 3.4 7.5 15.0 -3.9 0.2
Irritable Bowel Disease (IBD) 1.6 3.7 7.2 -2.7 -0.5
Ulcerative Colitis (UC) 0.2 0.4 0.8 -0.9 -0.2
Major Depression (MDD) 3.5 4.2 6.2 -2.5 1.5
Reaction Time 3.4 6.4 6.8 -2.6 2.5
Verbal and Numeric Reasoning (VNR) 0.3 0.6 0.8 -0.9 -0.7
Breast Cancer 0.4 1.1 1.3 -0.9 -1.2
Ovarian Cancer 0.7 0.9 1.4 -0.6 1.2
Prostate Cancer 3.4 4.8 9.4 -0.5 -3.1
Age at First Birth 0.0 0.0 0.0 0.1 -0.2
Bipolar Disorder (2011) 0.4 0.4 0.8 -0.0 -0.9
Body Mass Index (BMI) (2010) 6.0 8.2 13.8 -1.6 3.7
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.1 -0.1
Crohns Disease (2012) 0.5 0.8 1.6 -1.3 0.2
Mean Putamen Volume 0.3 0.3 0.6 -0.8 -0.1
Fasting Glucose 3.2 3.8 6.4 1.1 -2.5
HbA1C 0.4 0.5 0.7 0.5 -0.8
HDL Cholesterol 0.8 1.3 1.4 1.2 -1.1
LDL Cholesterol 0.4 0.6 0.8 -0.9 0.6
Lupus 0.6 0.9 1.6 -1.3 -0.4
Neuroticism (2016) 0.4 0.6 1.2 -0.3 1.1
Primary Biliary Cirrhosis 2.8 4.0 4.6 2.1 -1.9
Rheumatoid Arthritis 1.6 2.3 2.5 1.4 -1.6
Schizophrenia (2014) 1.4 3.1 3.3 -1.8 -1.7
Triglycerides 1.1 1.8 3.0 -0.7 1.7
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.3 0.4 0.6
Ulcerative Colitis 0.3 0.5 0.9 -0.3 -0.9
Blood Eosinophil Count 1.1 8.7 16.8 -4.1 0.7
Blood Platelet Count 0.6 6.4 9.9 3.1 1.7
Blood Red Count 0.3 3.1 4.4 -2.1 1.4
Blood White Count 0.4 2.7 2.9 -1.7 -1.6
Heel T-Score 0.4 3.5 7.1 -2.7 -0.0
BMI 1.4 8.2 16.3 0.2 4.0
Height 0.6 12.3 24.6 5.0 -0.2
Waist Hip Ratio (WHR) 1.7 7.8 14.1 -3.8 1.2
Systolic Blood Pressure 4.1 20.3 27.9 -5.3 -3.6
Smoking Status 0.8 2.0 3.6 0.6 -1.9
Allergy or Eczema 1.3 3.4 6.0 0.9 -2.4
Cardiovascular Disease 2.3 7.5 14.4 -3.8 -0.8
Hypothyroidism (self reported) 0.4 0.9 1.3 1.1 -0.7
Respiratory disease 0.0 0.0 0.0 0.2 -0.1
Type 2 Diabetes (T2D) (2018) 1.8 3.4 4.8 -1.4 2.2
Lung FEV1/FVC ratio 5.8 29.4 33.5 5.0 -5.8
Lung FVC 0.2 0.8 1.5 1.2 0.2
Neuroticism 0.4 1.1 1.9 -0.5 1.4
Chronotype (morning person) 0.4 0.9 1.7 0.1 -1.3
Hair Pigment 0.1 2.9 4.8 2.2 -0.9
Tanning 0.4 5.1 10.2 -0.2 -3.2
Hand grip strength (left) 2.4 6.4 8.4 2.9 -2.1
Number of treatments/medications taken 0.1 0.2 0.3 0.5 -0.4
Average weekly spirits intake 5.9 7.4 9.9 2.2 -3.1
Sensitivity / hurt feelings 0.1 0.2 0.5 -0.7 0.2
Frequency of depressed mood in last 2 weeks 1.2 1.6 2.1 -1.1 1.5
Hearing difficulty/problems: Yes 0.9 1.4 2.5 0.6 1.6
Relative age of first facial hair 0.5 1.1 2.1 -1.5 -0.1
Other serious medical condition/disability diagnosed by doctor 1.7 2.2 3.6 0.9 1.9
Ever used hormone-replacement therapy (HRT) 1.2 1.6 2.3 -0.9 1.5
Ever had hysterectomy (womb removed) 2.5 2.8 4.6 -2.1 -1.0
Systolic blood pressure, automated reading 1.9 5.6 9.1 -3.0 -1.5
Eye problems/disorders: Diabetes related eye disease 2.1 2.4 4.1 0.8 2.0
Angina 0.1 0.1 0.2 0.2 0.4
Medication for hormone replacement therapy 0.2 0.2 0.3 0.2 -0.6
Vitamin and mineral supplements 1.0 1.3 2.5 -1.6 0.4
Supplements: Zinc 1.0 1.1 1.6 0.7 -1.3
Medication: Co-codamol 0.2 0.3 0.5 -0.7 0.3
Medication: Metformin 3.4 4.8 6.0 -1.9 2.5
Diabetes (father) 0.6 0.7 1.4 1.2 0.1
Diabetes (mother) 1.3 1.7 2.0 1.2 -1.4
Severe depression (siblings) 1.7 1.9 3.0 0.9 1.7
Pack years adult smoking proportion 2.6 3.9 6.9 -2.6 1.0
Impedance of leg (right) 0.7 3.4 5.9 -2.4 -1.0
Leg fat-free mass (left) 0.7 3.6 4.2 2.0 1.8
Trunk fat percentage 4.2 16.8 26.4 -2.7 5.1
Hand grip strength (right) 2.2 5.9 8.1 2.8 -1.9
Townsend deprivation index at recruitment 1.2 1.8 2.3 -1.5 1.1
Current tobacco smoking 0.3 0.5 0.5 -0.7 -0.7
Average weekly fortified wine intake 0.6 0.7 1.4 0.3 -1.2
Maternal smoking around birth 1.1 1.5 2.7 0.6 -1.6
Fed-up feelings 2.4 4.4 6.2 -1.6 2.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.3 2.2 -0.5 1.5
Relative age voice broke 0.7 1.0 2.0 -0.2 -1.4
Taking other prescription medications 0.6 0.9 1.3 -0.7 1.2
Age when periods started (menarche) 0.0 0.1 0.2 -0.1 -0.4
Bilateral oophorectomy (both ovaries removed) 2.3 2.7 4.9 -2.2 0.7
Heel bone mineral density (BMD) T-score, automated (left) 1.5 3.5 5.5 -2.4 1.2
Tinnitus: Yes, but not now, but have in the past 0.0 0.0 0.0 -0.1 -0.1
Qualifications: CSEs or equivalent 0.6 0.8 1.0 1.0 -0.8
Serious illness, injury or assault to yourself 1.7 2.0 2.5 1.2 -1.6
High blood pressure 2.1 6.0 8.8 -3.0 -1.8
Hayfever, allergic rhinitis or eczema 1.1 2.3 4.3 0.5 -2.1
Multivitamins +/- minerals 0.9 1.1 2.1 0.3 -1.5
Stomach or abdominal pain in last month 0.2 0.2 0.4 0.2 0.6
Supplements: Glucosamine 2.6 3.4 4.3 2.1 -1.6
Diverticular disease/diverticulitis (self-reported) 5.9 7.0 9.5 2.1 -3.1
Medication: Atenolol 0.7 0.9 1.3 -0.7 1.1
Medication: Levothyroxine sodium 0.2 0.4 0.7 0.8 -0.2
Sitting height 0.2 1.6 2.6 1.6 0.9
Chronic bronchitis/emphysema (father) 0.4 0.5 0.9 0.3 1.0
High blood pressure (mother) 0.9 1.3 2.6 -1.6 -0.0
Body mass index (BMI) 1.6 6.8 13.4 -0.4 3.7
Impedance of leg (left) 0.4 2.2 3.8 -1.9 -0.8
Leg predicted mass (left) 0.8 4.0 5.0 2.2 1.7
Trunk fat mass 2.4 10.5 19.5 -1.2 4.4
Waist circumference 1.5 5.6 10.2 -1.0 3.2
Number of incorrect matches in round 1.0 1.7 2.1 1.1 -1.4
Past tobacco smoking 1.4 2.6 4.0 -1.1 2.0
Alcohol usually taken with meals 3.8 6.2 12.1 -0.6 -3.5
Nervous feelings 1.7 3.2 4.6 -1.3 2.1
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.8 2.1 -1.2 1.5
Hearing difficulty/problems with background noise 0.1 0.2 0.3 0.2 0.5
Hair/balding pattern: Pattern 2 1.1 1.4 2.1 0.8 -1.4
Had menopause 2.1 2.7 3.3 -1.8 1.4
Had other major operations 0.1 0.2 0.2 -0.3 -0.5
Forced vital capacity (FVC) 0.6 2.2 4.5 2.1 0.1
Heel bone mineral density (BMD) T-score, automated (right) 2.1 4.8 7.1 -2.7 1.6
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 1.6 -1.3 -0.7
Qualifications: None of the above 0.2 0.4 0.6 -0.8 0.4
Financial difficulties in last 2 years 1.6 2.1 4.1 -2.0 0.3
Mouth/teeth dental problems 1.0 1.5 2.4 0.7 -1.6
Heart attack 0.3 0.4 0.5 -0.6 0.7
Allergy 1.2 2.6 4.9 -0.6 2.2
Pain all over the body in last month 0.2 0.2 0.4 -0.1 -0.7
Diabetes (self-reported) 1.9 2.9 4.1 -1.3 2.0
Hayfever/allergic rhinitis (self-reported) 2.6 3.5 5.3 1.3 -2.3
Medication: Ramipril 1.8 2.4 4.7 -0.2 -2.2
Medication: Simvastatin 1.2 1.7 2.0 -1.4 1.2
Fluid intelligence score 1.1 2.4 4.6 -2.1 -0.3
Illnesses of siblings 2.3 3.2 6.3 2.5 -0.4
Neuroticism score 1.0 2.2 2.6 -1.3 1.6
Weight 1.0 5.0 9.3 0.9 3.1
Impedance of arm (right) 3.5 16.5 28.0 -5.3 2.2
Arm fat percentage (right) 3.6 14.4 22.0 -2.6 4.7
Trunk fat-free mass 2.1 12.2 22.3 4.7 -1.5
Hip circumference 1.0 4.3 7.8 0.9 2.8
Time employed in main current job 0.1 0.1 0.2 -0.0 -0.4
Alcohol intake versus 10 years previously 0.6 0.9 1.6 -0.4 1.2
Father’s age at death 0.3 0.4 0.5 0.6 -0.7
Worrier / anxious feelings 0.2 0.4 0.4 0.6 0.6
Frequency of tiredness / lethargy in last 2 weeks 2.4 3.9 4.9 -1.7 2.2
Falls in the last year 2.2 2.9 4.8 -2.2 1.1
Hair/balding pattern: Pattern 3 0.3 0.5 0.8 -0.5 0.9
Number of live births 0.1 0.2 0.2 -0.3 -0.4
Forced expiratory volume in 1-second (FEV1) 1.9 6.5 10.6 3.3 -1.6
Pulse rate 0.8 1.4 2.8 1.7 0.1
Happiness 0.7 0.8 1.6 -0.2 1.3
Noisy workplace 0.3 0.3 0.6 0.8 0.2
Qualifications: A levels/AS levels or equivalent 0.1 0.1 0.2 -0.3 0.4
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 1.1 -1.1 0.3
Mouth/teeth dental problems: Dentures 0.2 0.4 0.8 0.1 0.9
Asthma 0.0 0.1 0.1 -0.3 -0.3
Medication: Ibuprofen (e.g. Nurofen) 5.3 6.7 9.7 3.1 -1.9
Medication: Cholesterol lowering 0.5 0.7 1.3 -0.4 1.1
Depression (self-reported) 1.6 2.0 2.3 -1.5 1.3
Medication: Lansoprazole 1.4 1.6 2.1 1.5 1.0
Prospective memory result 2.1 2.5 4.8 2.2 0.5
Lung cancer (father) 4.6 5.4 10.2 -3.2 0.7
Illnesses of mother 2.5 3.1 3.6 1.9 -1.6
Forced expiratory volume in 1-second (FEV1), Best measure 1.8 5.8 8.8 3.0 -1.7
Pulse wave Arterial Stiffness index 1.1 1.3 1.6 1.0 -1.3
Impedance of arm (left) 3.8 17.6 29.4 -5.4 2.4
Arm fat mass (right) 2.0 8.3 15.9 -0.8 4.0
Trunk predicted mass 2.1 12.1 22.1 4.7 -1.5
Standing height 0.6 6.0 10.8 3.3 -1.1
Length of working week for main job 2.3 2.5 2.9 -1.7 1.5
Exposure to tobacco smoke at home 0.9 1.0 1.0 1.0 -1.0
Breastfed as a baby 1.6 1.9 3.8 0.3 -1.9
Tense / ‘highly strung’ 0.9 1.4 2.8 -0.2 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.4 2.1 3.0 -1.7 1.1
Hair/balding pattern: Pattern 4 0.7 1.7 2.2 -1.1 1.5
Birth weight of first child 0.5 0.8 1.0 -1.0 0.8
Peak expiratory flow (PEF) 2.8 6.6 7.8 2.8 -2.3
Pulse wave reflection index 1.3 1.7 3.3 0.2 -1.8
Ever highly irritable/argumentative for 2 days 1.9 2.2 3.5 -1.9 1.0
Loud music exposure frequency 0.4 0.4 0.7 0.8 0.4
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 1.4 1.2 0.5
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 0.8 -0.9 -0.7
Blood clot in the leg (DVT) 0.8 1.0 1.8 1.4 -0.4
Medication: Paracetamol 2.0 3.3 6.6 2.6 -0.0
Headache pain in last month 0.1 0.1 0.2 -0.3 0.4
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 2.3 1.5 -0.2
Glaucoma (self-reported) 4.3 5.0 5.3 2.3 -2.2
Gout (self-reported) 0.1 0.2 0.3 0.6 0.1
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 1.8 1.3 0.3
Medication: Amlodipine 0.5 0.7 0.8 -0.8 -0.9
Medication: Ventolin 100micrograms inhaler 0.9 1.2 2.1 -1.4 0.6
Birth weight 1.6 3.6 7.0 0.3 2.6
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.3 1.1 0.0
High blood pressure (siblings) 1.4 2.0 3.8 -2.0 0.3
Forced vital capacity (FVC), Best measure 0.6 2.1 3.3 1.8 -1.0
Body fat percentage 3.8 14.9 23.2 -2.6 4.8
Leg fat percentage (right) 2.4 8.7 14.1 -1.8 3.8
Arm fat-free mass (right) 2.0 10.4 20.6 4.5 -0.5
Exposure to tobacco smoke outside home 1.7 2.3 3.7 -1.9 0.9
Comparative body size at age 10 3.3 9.0 13.7 -2.1 3.7
Number of full brothers 0.2 0.2 0.3 0.4 0.5
Worry too long after embarrassment 0.9 1.5 1.7 -1.3 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 0.3 -0.4 -0.6
Wheeze or whistling in the chest in last year 0.9 1.6 2.9 -1.7 0.5
Number of children fathered 3.5 3.9 6.2 1.3 -2.5
Reason for reducing amount of alcohol drunk: Health precaution 0.0 0.0 0.0 0.1 0.1
Age at first live birth 0.1 0.2 0.4 0.1 -0.6
Pulse wave peak to peak time 0.9 1.0 1.2 -0.9 1.1
Health satisfaction 2.5 3.3 4.4 -1.5 2.1
Shortness of breath walking on level ground 0.4 0.5 0.9 -0.9 0.4
Qualifications: College or University degree 0.5 1.7 2.5 1.0 -1.6
Eye problems/disorders: None of the above 0.4 0.4 0.6 -0.5 -0.8
Mouth/teeth dental problems: Loose teeth 0.0 0.0 0.1 0.1 0.2
Emphysema/chronic bronchitis 1.1 1.2 1.9 1.4 -0.7
Medication for pain relief, constipation, heartburn 1.0 1.7 3.4 -1.8 -0.1
Neck or shoulder pain in last month 1.5 2.2 3.9 -0.6 2.0
Medication: Blood pressure 0.9 1.7 3.3 -1.8 -0.2
Angina (self-reported) 0.1 0.1 0.1 0.3 0.2
Migraine (self-reported) 0.1 0.1 0.3 0.0 -0.5
Medication: Ibuprofen 4.9 5.9 8.9 3.0 -1.7
Medication: Allopurinol 0.0 0.1 0.1 0.3 0.2
Medication: Omeprazole 1.2 1.4 1.9 1.0 1.4
Medication: Seretide 50 evohaler 0.1 0.1 0.3 -0.5 -0.1
Mean time to correctly identify matches 1.6 3.1 4.0 -2.0 1.5
Heart disease (mother) 0.7 0.9 1.4 -0.5 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 1.9 -0.1 -1.4
Whole body fat mass 2.3 9.6 18.2 -1.0 4.3
Leg fat mass (right) 1.9 7.5 14.6 -0.6 3.8
Arm predicted mass (right) 1.8 9.3 18.5 4.3 -0.4
Pulse rate, automated reading 0.8 2.5 3.2 1.3 1.8
Alcohol intake frequency. 3.5 8.1 12.5 -1.9 3.5
Comparative height size at age 10 1.0 5.6 8.7 3.0 -1.6
Number of full sisters 0.8 0.9 1.9 -1.4 0.1
Suffer from ‘nerves’ 1.3 2.0 3.6 -0.6 1.9
Overall health rating 3.2 6.9 9.6 -2.1 3.1
Chest pain or discomfort 0.5 0.8 1.5 -1.2 0.1
Had major operations 1.2 1.4 1.8 1.3 -1.0
Age at last live birth 0.4 0.6 1.1 -0.1 -1.1
Family relationship satisfaction 1.6 2.0 2.6 -1.1 1.6
Leg pain on walking 0.0 0.0 0.0 -0.1 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.2 -0.4 0.2
Commuting to job workplace: Car/motor vehicle 0.9 1.0 1.5 1.2 0.8
Illness, injury, bereavement, stress in last 2 years 4.2 5.1 10.2 3.2 -0.2
Medication: Aspirin 3.4 4.5 4.7 -2.1 2.2
Supplements: Vitamin C 0.1 0.1 0.1 0.3 0.2
Knee pain experienced in last month 1.5 2.3 4.5 -0.0 2.1
Hypertension (Self-reported) 1.3 3.5 4.5 -2.1 -1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.8 2.1 3.0 1.7 -1.0
Illnesses of father: Heart disease 1.1 1.5 2.9 1.7 -0.2
Illnesses of siblings: Diabetes 0.3 0.4 0.7 -0.8 0.1
Smoking status: Previous 2.0 3.0 5.0 1.1 -2.2
Forced expiratory volume in 1-second (FEV1), predicted 1.3 2.7 5.2 2.3 -0.4
Whole body fat-free mass 1.4 8.1 16.2 4.0 -0.2
Leg fat-free mass (right) 0.9 4.7 6.7 2.6 1.7
Arm fat percentage (left) 4.2 16.6 25.6 -2.7 5.1
Average weekly red wine intake 1.6 2.3 3.5 1.1 -1.9
Handedness (chirality/laterality): Left-handed 0.4 0.5 0.6 0.8 0.6
Mood swings 0.5 0.9 1.6 0.4 1.3
Loneliness, isolation 2.1 2.8 5.4 -2.3 0.5
Long-standing illness, disability or infirmity 1.6 2.5 5.0 0.2 2.2
Ever had bowel cancer screening 1.5 1.8 3.5 1.9 -0.3
Diabetes diagnosed by doctor 2.9 4.7 8.2 -1.1 2.9
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.2 0.5 0.2
Friendships satisfaction 2.1 2.5 3.0 -1.5 1.7
Qualifications: nursing, teaching 0.6 1.0 1.9 1.4 0.2
Commuting to job workplace: Walk 0.5 0.6 1.0 0.4 -1.0
Eye problems/disorders: Cataract 0.2 0.3 0.3 0.5 0.6
Mouth/teeth dental problems: Mouth ulcers 1.1 1.7 3.0 0.6 1.7
Medication for cholesterol 1.2 1.8 3.3 1.8 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.3 0.4 -0.5
Back pain experienced in last month 1.7 2.5 4.4 0.8 2.1
Mineral and other dietary supplements 3.8 5.1 10.0 -3.2 -0.4
Breast cancer (self-reported) 1.1 1.4 2.7 0.1 1.6
Asthma (self-reported) 0.0 0.0 0.1 -0.1 -0.3
Osteoporosis (self-reported) 1.6 2.0 3.8 1.9 -0.5
Osteoarthritis (self-reported) 0.9 1.2 2.0 1.4 0.6
Medication: Aspirin 2.6 3.3 3.8 -1.7 2.0
Medication: Gliclazide 0.4 0.4 0.8 -0.9 0.2
Illnesses of father: None of the above (group 1) 0.7 0.9 1.7 -1.3 0.1
Smoking status: Current 0.4 0.6 1.1 -1.1 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.1 3.3 0.9 -1.8
Whole body water mass 1.4 8.1 16.1 4.0 -0.3
Leg predicted mass (right) 0.9 4.7 6.7 2.6 1.6
Arm fat mass (left) 2.1 8.8 16.5 -1.1 4.1
Number of self-reported non-cancer illnesses 0.0 0.0 0.0 -0.2 0.1
Average weekly champagne plus white wine intake 0.3 0.5 0.6 0.6 -0.8
Miserableness 1.4 2.5 3.2 -1.4 1.8
Guilty feelings 0.1 0.2 0.3 -0.5 -0.3
Wears glasses or contact lenses 2.5 2.8 4.3 2.1 -1.2
Ever taken oral contraceptive pill 0.3 0.3 0.6 0.2 -0.8
Hearing aid user 0.9 1.0 1.1 1.0 1.0
Mother’s age at death 0.3 0.3 0.6 0.8 0.2
Financial situation satisfaction 1.3 1.6 2.2 -1.5 1.0
Tinnitus: Yes, now most or all of the time 0.8 0.9 1.1 0.9 1.0
Commuting to job workplace: Public transport 0.6 0.7 1.1 -0.6 -1.0
Eye problems/disorders: Glaucoma 1.3 1.5 1.9 1.1 -1.4
Medication: Blood pressure 1.1 2.1 4.0 -2.0 0.3
Pain type(s) experienced in last month: Hip pain 0.5 0.6 1.1 1.0 -0.4
Supplements: Fish oil (including cod liver oil) 1.7 2.3 3.9 2.0 0.8
High cholesterol (Self-reported) 0.3 0.6 1.1 0.3 1.0
Medication: Bendroflumethiazide 0.6 0.8 0.9 -0.9 1.0
Medication: Paracetamol 1.2 1.9 3.7 1.9 -0.3
Medication: Lisinopril 1.8 2.3 4.6 -0.3 2.1
Medication: Atorvastatin 0.5 0.6 1.1 -0.3 1.0
Illnesses of father: High blood pressure 0.5 0.6 1.0 -1.0 -0.4
Alcohol drinker status: Never 0.3 0.3 0.3 -0.6 -0.5
Ever smoked 2.5 4.4 8.5 0.5 -2.9
Basal metabolic rate 1.0 5.3 10.2 3.2 0.7
Leg fat percentage (left) 2.3 8.4 14.8 -1.4 3.9
Arm fat-free mass (left) 1.7 8.4 16.7 4.1 -0.4
Number of operations (self-reported) 1.1 1.7 2.6 0.9 -1.6
Average weekly beer plus cider intake 0.8 1.1 2.2 -0.2 1.5
Irritability 0.8 1.4 2.4 -1.5 0.7
Risk taking 1.7 2.4 4.1 -2.0 -0.9
Ever had prostate specific antigen (PSA) test 3.2 3.7 4.4 2.1 -1.7
Fractured/broken bones in last 5 years 0.9 1.2 2.0 1.4 -0.6
Age started oral contraceptive pill 1.1 1.4 2.4 -0.6 1.5
Diastolic blood pressure, automated reading 2.9 8.9 13.7 -3.7 -2.0
Ever depressed for a whole week 1.7 2.1 3.8 -0.6 -2.0
Unable to work because of sickness or disability 0.5 0.7 1.0 -0.6 1.0
Commuting to job workplace: Cycle 2.7 3.2 4.5 -2.1 -1.4
Myopia 0.4 0.6 0.8 -0.6 0.9
Vascular/heart problems diagnosed by doctor 2.2 5.9 10.9 3.3 1.0
Cholesterol lowering medication 2.4 3.5 3.8 -1.8 2.0
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 0.7 0.8 0.7
Pain experienced in last month 1.2 2.1 3.6 -0.7 -1.9
Supplements: Calcium 6.3 7.0 9.9 3.2 -2.0
Basal cell carcinoma (self-reported) 4.0 4.8 8.8 -0.9 3.0
Heart attack/myocardial infarction (self-reported) 0.2 0.2 0.3 -0.3 0.6
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.0 1.0 -0.2
Heart disease (siblings) 1.6 1.9 3.8 -0.2 1.9
Alcohol drinker status: Previous 1.8 2.0 2.4 -1.3 1.6
Pack years of smoking 2.8 4.1 6.4 -2.5 1.3
Impedance of whole body 1.8 8.9 17.2 -4.2 0.8
Leg fat mass (left) 2.1 8.0 15.9 -0.3 4.0
Arm predicted mass (left) 1.7 8.7 17.1 4.1 -0.6