[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr2:62,658,256-66,055,613

Best TWAS P=9.83e-22 · Best GWAS P=7.45e-22 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CEP68	0.15	0.11	lasso	4	0.12	6.7e-10	-9.2	9.4	4.2e-21	-0.95	0.05	0.95	FALSE
2	GTEx	Adipose Subcutaneous	WDPCP	0.23	0.29	lasso	19	0.29	4.6e-24	-5.0	-5.2	1.7e-07	0.01	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	MDH1	0.24	0.28	lasso	7	0.27	2.5e-14	-5.0	-5.2	1.8e-07	0.02	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	WDPCP	0.09	0.05	lasso	7	0.06	2.8e-04	-4.9	-5.3	1.4e-07	0.02	0.43	0.10	FALSE
5	GTEx	Artery Aorta	CEP68	0.10	0.15	lasso	5	0.14	3.4e-08	-9.6	9.6	9.8e-22	-1.00	0.00	1.00	TRUE
6	GTEx	Artery Aorta	WDPCP	0.16	0.05	lasso	11	0.07	1.4e-04	-5.1	-5.3	1.4e-07	-0.01	0.91	0.03	FALSE
7	GTEx	Artery Coronary	CEP68	0.20	0.04	lasso	7	0.03	3.6e-02	-9.6	9.2	2.4e-20	-0.98	0.01	0.96	FALSE
8	GTEx	Artery Tibial	CEP68	0.24	0.19	lasso	5	0.20	1.8e-15	-9.2	9.6	1.4e-21	-0.98	0.00	1.00	FALSE
9	GTEx	Artery Tibial	WDPCP	0.08	0.02	enet	24	0.04	4.0e-04	6.1	-6.6	3.3e-11	0.02	0.06	0.88	FALSE
10	GTEx	Brain Caudate basal ganglia	ACA59	0.16	0.04	enet	24	0.10	9.3e-04	6.6	7.1	1.6e-12	0.04	0.04	0.66	FALSE
11	GTEx	Brain Cerebellum	WDPCP	0.14	0.00	enet	12	0.00	3.1e-01	5.8	-7.2	9.0e-13	0.04	0.08	0.64	TRUE
12	GTEx	Breast Mammary Tissue (Male)	MDH1	0.02	-0.01	enet	8	-0.01	4.4e-01	-4.6	-5.7	1.3e-08	-0.05	0.03	0.07	FALSE
13	GTEx	Cells Transformed fibroblasts	CEP68	0.17	0.14	lasso	3	0.12	1.9e-09	-9.6	9.6	1.1e-21	-1.00	0.00	1.00	FALSE
14	GTEx	Cells Transformed fibroblasts	MDH1	0.13	0.09	lasso	9	0.10	1.1e-07	-5.4	-5.9	4.4e-09	0.01	0.95	0.04	FALSE
15	GTEx	Cells Transformed fibroblasts	ACA59	0.09	0.07	lasso	4	0.08	1.6e-06	-4.3	5.6	2.4e-08	0.02	0.65	0.27	FALSE
16	GTEx	Colon Sigmoid	WDPCP	0.15	0.05	lasso	4	0.03	3.0e-02	-4.4	-5.8	7.8e-09	-0.01	0.48	0.10	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	CEP68	0.25	0.01	lasso	4	0.08	8.6e-04	-8.3	7.0	2.6e-12	-0.76	0.03	0.72	FALSE
18	GTEx	Esophagus Mucosa	WDPCP	0.06	0.03	lasso	3	0.04	1.7e-03	-5.2	-6.2	5.6e-10	0.00	0.42	0.29	FALSE
19	GTEx	Esophagus Muscularis	CEP68	0.16	0.13	enet	7	0.17	2.2e-10	-9.2	9.3	1.6e-20	-0.93	0.03	0.97	FALSE
20	GTEx	Esophagus Muscularis	WDPCP	0.09	0.09	lasso	4	0.06	2.5e-04	-5.6	-5.8	8.4e-09	0.06	0.89	0.07	FALSE
21	GTEx	Heart Atrial Appendage	CEP68	0.26	0.20	lasso	3	0.19	4.6e-09	-9.6	9.4	4.7e-21	-0.99	0.00	1.00	FALSE
22	GTEx	Heart Left Ventricle	CEP68	0.14	0.05	lasso	7	0.05	1.7e-03	-9.2	9.2	2.3e-20	-0.95	0.00	0.99	FALSE
23	GTEx	Heart Left Ventricle	WDPCP	0.11	0.09	enet	14	0.08	7.8e-05	-4.5	-5.3	1.1e-07	0.00	0.84	0.05	FALSE
24	GTEx	Lung	CEP68	0.12	0.13	lasso	3	0.12	1.6e-09	-9.2	8.8	2.0e-18	-0.95	0.02	0.98	FALSE
25	GTEx	Lung	WDPCP	0.13	0.05	enet	29	0.09	1.2e-07	-5.4	-5.5	3.4e-08	0.01	0.56	0.44	FALSE
26	GTEx	Muscle Skeletal	CEP68	0.13	0.07	lasso	7	0.07	2.1e-07	-9.2	8.6	8.5e-18	-0.93	0.05	0.95	FALSE
27	GTEx	Nerve Tibial	CEP68	0.11	0.01	enet	29	0.03	2.4e-03	-9.2	6.9	6.3e-12	-0.65	0.01	0.94	FALSE
28	GTEx	Nerve Tibial	MDH1	0.14	0.17	lasso	6	0.17	2.9e-12	-4.8	-5.3	1.1e-07	0.02	1.00	0.00	FALSE
29	GTEx	Nerve Tibial	WDPCP	0.08	0.02	enet	16	0.05	2.2e-04	5.0	-7.1	1.1e-12	0.00	0.03	0.95	FALSE
30	GTEx	Nerve Tibial	UGP2	0.06	0.01	enet	12	0.02	8.7e-03	-4.9	-5.7	1.4e-08	0.02	0.49	0.06	FALSE
31	GTEx	Ovary	CEP68	0.38	0.26	lasso	7	0.24	1.6e-06	-9.2	9.1	1.1e-19	-0.96	0.01	0.98	FALSE
32	GTEx	Pancreas	CEP68	0.28	0.11	lasso	6	0.13	5.6e-06	-9.2	8.5	1.8e-17	-0.82	0.01	0.97	FALSE
33	GTEx	Pancreas	WDPCP	0.13	0.06	lasso	6	0.04	1.2e-02	-4.5	-5.4	8.3e-08	0.02	0.38	0.33	FALSE
34	GTEx	Skin Sun Exposed Lower leg	MDH1	0.03	0.02	lasso	3	0.03	1.9e-03	-4.4	-5.6	2.7e-08	-0.01	0.31	0.04	FALSE
35	GTEx	Stomach	WDPCP	0.07	0.03	enet	17	0.03	1.1e-02	5.9	-6.9	5.3e-12	0.05	0.28	0.12	FALSE
36	GTEx	Testis	CEP68	0.26	0.27	lasso	5	0.26	5.3e-12	-9.6	9.5	2.5e-21	-1.00	0.00	1.00	FALSE
37	GTEx	Testis	WDPCP	0.17	0.08	enet	15	0.12	4.2e-06	-5.1	-5.3	1.2e-07	-0.01	0.76	0.13	FALSE
38	GTEx	Thyroid	WDPCP	0.07	0.03	lasso	6	0.06	2.1e-05	-4.0	-5.8	5.5e-09	0.04	0.49	0.46	FALSE
39	GTEx	Thyroid	AC074289.1	0.13	0.07	lasso	10	0.06	1.1e-05	-5.0	-5.6	2.3e-08	0.01	0.59	0.26	FALSE
40	GTEx	Whole Blood	WDPCP	0.05	0.04	lasso	2	0.03	5.5e-04	-5.1	-5.2	1.9e-07	0.00	0.73	0.08	FALSE
41	METSIM	Adipose	MDH1	0.10	0.21	enet	32	0.20	1.5e-29	-5.0	-5.1	2.8e-07	0.02	1.00	0.00	FALSE
42	METSIM	Adipose	RAB1A	0.06	0.00	bslmm	460	0.02	6.9e-04	-7.5	-5.5	5.2e-08	0.27	0.06	0.06	FALSE
43	METSIM	Adipose	WDPCP	0.10	0.12	blup	488	0.15	5.4e-22	-4.4	-7.0	2.0e-12	0.00	1.00	0.00	FALSE
44	YFS	Blood	CEP68	0.08	0.10	lasso	7	0.10	2.9e-30	-8.3	9.0	2.9e-19	-0.95	0.00	1.00	FALSE
45	The Cancer Genome Atlas	Breast Invasive Carcinoma	C2orf86	0.05	0.02	blup	141	0.05	9.4e-10	-5.2	-6.5	5.7e-11	0.03	0.99	0.01	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CEP68	0.12	0.07	blup	55	0.06	1.7e-04	-8.3	8.4	5.4e-17	-0.92	0.00	0.99	FALSE
47	The Cancer Genome Atlas	Prostate Adenocarcinoma	C2orf86	0.05	0.02	blup	141	0.04	2.1e-05	-4.9	-6.4	1.4e-10	0.03	0.74	0.24	FALSE
48	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEP68	0.04	0.03	lasso	4	0.02	4.0e-03	-9.2	9.3	2.0e-20	-0.98	0.00	0.98	FALSE
49	The Cancer Genome Atlas	Soft Tissue Sarcoma	C2orf86	0.12	0.07	blup	141	0.08	2.7e-05	-5.6	-6.5	9.8e-11	0.05	0.55	0.23	FALSE
50	The Cancer Genome Atlas	Thyroid Carcinoma	C2orf86	0.05	0.05	blup	141	0.06	1.1e-06	-4.9	-7.0	2.0e-12	0.03	0.80	0.18	FALSE