Best TWAS P=1.28e-08 · Best GWAS P=1.82e-07 conditioned to 0.664
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FBXO41 | 0.08 | 0.03 | blup | 281 | 0.03 | 1.5e-04 | 5.1 | 5.7 | 1.3e-08 | 0.88 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Esophagus Mucosa | PRADC1 | 0.13 | 0.04 | enet | 10 | 0.05 | 2.1e-04 | 4.7 | -5.6 | 1.8e-08 | -0.89 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Esophagus Muscularis | PRADC1 | 0.20 | 0.14 | enet | 11 | 0.10 | 1.7e-06 | 5.2 | -5.4 | 5.5e-08 | -0.98 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C2orf7 | 0.03 | 0.03 | lasso | 2 | 0.03 | 4.7e-03 | 5.1 | -5.1 | 3.0e-07 | -0.99 | 0.01 | 0.82 | FALSE |