TWAS hub - C2orf7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0360	0.0232	0.0033	0.015	0.023	0.017	NA	0.017	0.0065	0.0013	0.005	NA	0.0045
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0178	0.0117	0.0088	0.009	0.010	0.007	NA	0.006	0.0260	0.0240	0.047	NA	0.0650
3	TCGA	Stomach Adenocarcinoma	0.0270	0.0170	0.0100	0.034	0.021	0.012	NA	0.027	0.0017	0.0120	0.044	NA	0.0047

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Number of self-reported non-cancer illnesses	10.5	18.3	21.7	-3.7	-4.4	-4.7
Verbal and Numeric Reasoning (VNR)	10.1	24.3	31.1	3.5	5.6	5.4
Medication: Blood pressure	9.9	17.5	21.8	-3.9	-4.0	-4.7
Unable to work because of sickness or disability	9.3	12.0	12.9	-3.4	-3.4	-3.6
Fluid intelligence score	8.6	17.9	23.0	3.1	4.8	4.6
Number of treatments/medications taken	8.2	14.8	19.3	-3.2	-3.9	-4.4
Medication: Atenolol	8.1	10.1	11.9	-3.0	-3.1	-3.5
Medication for cholesterol, blood pressure or diabetes	7.5	12.5	16.2	3.1	3.4	4.0
Intelligence (Savage-Jansen 2018)	6.4	19.8	24.3	3.6	4.9	4.7
Qualifications: A levels/AS levels or equivalent	5.9	13.1	16.4	2.8	4.1	3.9
Qualifications: College or University degree	5.7	18.1	21.1	3.9	4.2	4.6
Depression (self-reported)	5.5	6.6	11.0	-1.2	-3.3	-2.7
Cardiovascular Disease	5.3	17.4	21.5	-3.6	-4.2	-4.6
Medication: Ramipril	5.3	6.8	7.3	-2.6	-2.5	-2.7
Taking other prescription medications	5.1	7.9	9.2	-2.6	-3.0	-2.8
Commuting to job workplace: Public transport	5.1	6.1	7.3	2.2	2.5	2.7
Vascular/heart problems diagnosed by doctor	4.7	12.8	14.8	3.6	3.2	3.9
Systolic blood pressure, automated reading	4.6	13.5	17.3	-2.9	-3.8	-4.2
Number of incorrect matches in round	4.6	7.6	9.5	-2.0	-3.1	-3.1
Pain type(s) experienced in last month: Hip pain	4.6	5.8	7.7	-2.8	-2.3	-2.1
Systolic Blood Pressure	4.5	22.6	26.2	-4.3	-4.8	-5.1
Medication: Omeprazole	4.4	5.2	10.8	0.2	-3.3	-2.2
Loud music exposure frequency	4.1	4.5	4.7	2.1	2.1	2.2
Medication: Cholesterol lowering	4.0	6.2	8.4	-2.9	-2.0	-2.5
Angina	3.9	5.1	6.2	-2.5	-2.1	-2.2
Age at last live birth	3.9	5.6	5.7	2.4	2.4	2.4
Medication: Lansoprazole	3.8	4.4	7.6	-1.0	-2.8	-2.1
Father’s age at death	3.7	4.9	5.6	2.2	2.1	2.4
Tinnitus: Yes, but not now, but have in the past	3.6	3.8	5.4	1.4	2.3	2.0
Angina (self-reported)	3.6	4.7	5.7	-2.4	-2.0	-2.1
High blood pressure	3.5	9.7	11.0	-3.2	-2.8	-3.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.5	4.6	5.1	-2.0	-2.2	-2.3
Hypertension (Self-reported)	3.5	9.8	11.4	-3.2	-2.8	-3.4
Serious illness, injury or assault to yourself	3.4	4.1	5.0	-2.2	-1.7	-2.1
Exposure to tobacco smoke at home	3.4	3.8	4.8	-2.2	-1.3	-2.2
Medication: Amlodipine	3.2	4.5	4.9	-2.0	-2.2	-2.2
Illnesses of father: None of the above (group 1)	3.1	3.9	4.8	1.9	1.8	2.2
Eye problems/disorders: None of the above	3.0	3.4	3.8	-1.7	-1.9	-2.0
Average weekly red wine intake	3.0	4.4	6.2	2.5	1.5	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.0	6.3	10.3	1.0	3.2	2.8
Hayfever/allergic rhinitis (self-reported)	2.9	3.8	4.2	-2.0	-1.8	-2.0
Back pain experienced in last month	2.9	4.3	6.2	-1.3	-2.5	-2.2
Medication: Omeprazole (e.g. Zanprol)	2.9	3.5	7.4	0.4	-2.7	-1.7
Birth weight of first child	2.8	5.1	6.2	1.8	2.4	2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.8	3.3	5.8	-0.8	-2.4	-1.8
Overall health rating	2.7	5.9	6.6	-2.2	-2.6	-2.5
Diastolic blood pressure, automated reading	2.7	8.4	10.8	-3.1	-2.2	-3.3
Stomach or abdominal pain in last month	2.6	3.2	5.6	-0.9	-2.4	-1.8
Forced expiratory volume in 1-second (FEV1)	2.6	8.8	14.0	1.0	3.7	3.4
Pulse rate, automated reading	2.6	8.3	11.4	-3.4	-2.2	-3.0
Average weekly champagne plus white wine intake	2.6	3.6	4.8	2.2	1.7	1.7
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.1	6.5	-1.0	-2.5	-2.2
Friendships satisfaction	2.5	3.1	4.0	1.6	1.7	2.0
Comparative body size at age 10	2.4	6.6	8.1	2.8	1.9	2.8
Myopia	2.4	3.5	3.8	1.9	1.8	1.9
Qualifications: None of the above	2.3	4.9	6.1	-2.5	-1.9	-2.2
Heart attack	2.3	3.0	4.3	-2.1	-1.5	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.3	11.7	0.9	3.4	3.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	3.6	-1.9	-1.9	-1.8
Osteoarthritis (self-reported)	2.3	3.0	4.2	-0.9	-2.0	-2.0
Health satisfaction	2.2	2.8	4.2	-1.1	-2.1	-1.7
Mineral and other dietary supplements	2.2	3.0	4.2	1.6	1.4	2.1
Respiratory disease	2.1	4.8	8.6	-1.2	-2.9	-2.0
Medication: Co-codamol	2.1	2.4	3.2	-1.5	-1.3	-1.8
Prospective memory result	2.0	2.5	3.2	-1.8	-1.2	-1.7
Heart attack/myocardial infarction (self-reported)	2.0	2.5	3.1	-1.8	-1.4	-1.6
Smoking Status	1.9	4.7	5.1	-2.3	-2.0	-2.2
Pulse rate	1.9	3.2	4.8	-2.2	-1.2	-1.9
Eye problems/disorders: Cataract	1.9	2.2	4.4	2.1	0.8	1.3
Supplements: Fish oil (including cod liver oil)	1.9	2.5	3.4	-1.8	-0.9	-1.9
Basal cell carcinoma (self-reported)	1.9	2.2	2.7	-1.5	-1.3	-1.6
Chronic bronchitis/emphysema (mother)	1.8	2.1	2.9	-1.0	-1.6	-1.7
Mean Putamen Volume	1.7	1.9	2.6	0.8	1.5	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.1	3.5	1.9	1.4	0.8
Medication: Gliclazide	1.7	2.0	3.0	-1.7	-0.9	-1.5
Major Depression (MDD)	1.6	2.0	2.5	-1.3	-1.4	-1.6
Commuting to job workplace: Walk	1.6	1.7	2.2	1.4	1.5	1.0
Medication: Lisinopril	1.6	2.1	5.3	-2.3	-0.4	-0.9
Commuting to job workplace: Cycle	1.6	2.0	3.2	0.7	1.5	1.8
Bipolar Disorder (2011)	1.5	1.4	2.0	-1.2	-0.9	-1.4
Chronic bronchitis/emphysema (father)	1.5	1.8	2.0	-1.4	-1.3	-1.3
Mouth/teeth dental problems: Dentures	1.5	2.5	3.7	-0.4	-1.9	-1.9
Commuting to job workplace: Car/motor vehicle	1.5	1.7	2.7	-0.6	-1.6	-1.5
Qualifications: nursing, teaching	1.5	2.3	3.2	1.8	0.9	1.7
Ever had prostate specific antigen (PSA) test	1.4	1.6	3.2	1.8	0.7	1.0
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	2.9	1.7	0.8	1.4
Schizophrenia (2018)	1.3	2.7	4.4	-1.5	-1.2	-2.1
Primary Biliary Cirrhosis	1.3	1.8	4.3	2.1	0.6	0.9
Forced vital capacity (FVC)	1.3	4.9	8.5	0.3	2.9	2.5
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	2.2	-0.8	-1.4	-1.5
Wheeze or whistling in the chest in last year	1.3	2.3	3.3	-1.2	-1.8	-1.4
Eye problems/disorders: Glaucoma	1.3	1.6	2.4	0.3	1.5	1.5
Bipolar Disorder or Schizophrenia	1.2	2.9	5.1	-1.4	-1.3	-2.3
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.3	1.6	1.0	1.2	1.3
Forced vital capacity (FVC), Best measure	1.2	4.6	8.2	0.2	2.9	2.3
Emphysema/chronic bronchitis	1.2	1.3	2.3	-0.4	-1.5	-1.2
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.9	1.7	0.6	1.0
Age at First Birth	1.1	1.6	2.8	0.6	1.7	1.3
Average weekly fortified wine intake	1.1	1.3	2.2	0.7	1.0	1.5
Medication: Simvastatin	1.1	1.6	2.5	-1.2	-1.0	-1.6
Lung cancer (father)	1.1	1.3	4.0	-2.0	-0.2	-0.1
Medication: Ventolin 100micrograms inhaler	1.1	1.5	1.9	-0.9	-1.3	-1.4
Schizophrenia (2014)	1.0	2.3	3.6	-1.5	-1.0	-1.9
Alcohol usually taken with meals	1.0	1.7	4.5	2.1	0.3	0.7
Financial difficulties in last 2 years	1.0	1.4	2.4	0.1	1.6	1.3
Worrier / anxious feelings	1.0	1.9	2.6	1.4	-1.6	-1.0
Breastfed as a baby	1.0	1.2	1.8	0.7	1.3	1.1
Number of full brothers	1.0	1.2	1.8	-0.0	-1.3	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	1.6	-1.1	-0.8	-1.3
Medication for pain relief, constipation, heartburn	1.0	1.6	2.8	0.6	1.7	1.3
Medication: Allopurinol	1.0	1.3	2.2	-1.5	-0.9	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	3.1	0.8	1.8	1.6
Hearing aid user	1.0	1.1	2.4	1.6	0.4	0.9
Medication: Atorvastatin	1.0	1.2	1.5	-1.1	-0.9	-1.2
Type 2 Diabetes (T2D) (2018)	0.9	1.6	3.5	-1.9	-0.5	-1.0
Diabetes (mother)	0.9	1.2	1.5	-1.1	-1.0	-1.2
Fed-up feelings	0.9	1.7	2.9	-0.6	-1.7	-1.3
Alcohol intake versus 10 years previously	0.9	1.3	2.3	-1.5	-0.7	-1.1
Blood clot in the leg (DVT)	0.9	1.2	2.2	1.5	0.4	1.1
Glaucoma (self-reported)	0.9	1.1	1.5	0.5	1.2	1.2
High blood pressure (siblings)	0.9	1.4	2.5	0.1	-1.6	-1.3
Age at first live birth	0.9	1.6	1.9	1.4	1.1	1.2
Illnesses of father: Heart disease	0.9	1.2	1.9	-0.4	-1.2	-1.4
Asthma (self-reported)	0.9	1.7	2.0	-1.4	-1.3	-1.1
Ever taken oral contraceptive pill	0.9	1.0	1.8	-0.4	1.3	1.1
Ever smoked	0.9	1.6	2.2	-1.1	-1.5	-1.3
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.1	-1.1	-1.0	-0.8
Blood White Count	0.8	5.9	8.0	-1.6	-2.8	-2.7
Relative age of first facial hair	0.8	1.6	3.1	0.6	1.8	1.2
Supplements: Zinc	0.8	0.9	1.3	-0.1	1.1	1.2
Past tobacco smoking	0.8	1.5	1.9	1.1	1.4	1.2
Illnesses of siblings	0.8	1.1	1.6	0.3	1.3	1.3
Asthma	0.8	1.5	1.8	-1.3	-1.3	-1.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.0	-0.2	-1.4	-0.9
Mean time to correctly identify matches	0.8	1.6	2.0	-1.2	-1.1	-1.4
Long-standing illness, disability or infirmity	0.8	1.3	1.7	-1.0	-1.0	-1.3
Number of operations (self-reported)	0.8	1.2	1.9	-0.3	-1.4	-1.3
Worry (Nagel 2018)	0.7	1.4	3.5	1.9	-0.7	-0.5
Body Mass Index (BMI) (2010)	0.7	1.0	1.7	1.3	0.7	0.9
Sensitivity / hurt feelings	0.7	1.2	2.6	0.2	-1.6	-1.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.2	0.9	0.9	1.1
Vitamin and mineral supplements	0.7	0.9	1.6	0.9	0.5	1.3
Nervous feelings	0.7	1.4	3.9	2.0	0.2	0.4
Peak expiratory flow (PEF)	0.7	1.6	2.9	-0.3	1.7	1.4
Number of full sisters	0.7	0.9	1.4	-0.9	1.2	0.6
Mood swings	0.7	1.3	1.4	-1.1	-1.1	-1.2
Ever had bowel cancer screening	0.7	0.8	1.6	-0.2	-1.3	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	1.0	1.0	0.8	0.8
High cholesterol (Self-reported)	0.7	1.2	2.4	-0.4	-1.0	-1.6
Triglycerides	0.6	0.9	1.1	-0.9	-1.0	-0.9
Severe depression (siblings)	0.6	0.7	1.1	-0.6	-1.1	-0.8
Qualifications: CSEs or equivalent	0.6	0.7	0.9	-0.9	-0.8	-0.8
Hair/balding pattern: Pattern 2	0.6	0.7	1.4	-1.2	-0.3	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.0	0.9	0.6	1.0
Length of working week for main job	0.6	0.7	1.1	0.3	1.0	0.9
Chest pain or discomfort	0.6	0.8	1.6	-0.4	-1.3	-0.9
Smoking status: Previous	0.6	0.9	1.2	-0.6	-1.1	-1.0
Smoking status: Current	0.6	1.0	2.0	-1.4	-0.6	-0.8
Medication: Blood pressure	0.6	1.1	1.7	-1.3	-0.7	-1.0
Ever depressed for a whole week	0.6	0.7	1.0	-0.8	-1.0	-0.7
Depressed Affect (Nagel 2018)	0.5	1.0	1.7	-0.5	-1.3	-0.9
Alzheimer’s Disease (in mother)	0.5	0.5	0.9	0.8	0.3	0.9
Ulcerative Colitis (UC)	0.5	0.9	1.6	0.2	-1.2	-1.1
Reaction Time	0.5	0.9	1.0	-0.9	-0.9	-1.0
Chronotype (morning person)	0.5	1.2	1.9	0.7	1.4	1.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	0.9	-0.2	0.8	1.0
Current tobacco smoking	0.5	0.8	1.4	-1.2	-0.6	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	0.8	-0.8	-0.9	-0.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.5	1.2	-0.4	0.2
High blood pressure (mother)	0.5	0.7	0.8	-0.9	-0.7	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.7	0.4	-1.3	-0.6
Mouth/teeth dental problems	0.5	0.7	0.9	0.6	0.9	0.9
Pain all over the body in last month	0.5	0.5	1.0	0.7	-1.0	-0.3
Happiness	0.5	0.7	1.1	-0.3	-1.0	-0.9
Pulse wave peak to peak time	0.5	0.6	1.7	1.3	-0.1	0.3
Medication: Ibuprofen	0.5	0.6	0.7	0.7	0.7	0.8
Medication: Seretide 50 evohaler	0.5	0.6	0.9	-1.0	-0.5	-0.8
Heart disease (mother)	0.5	0.6	1.1	0.6	1.1	0.6
Alcohol intake frequency.	0.5	1.3	2.3	-0.4	-1.5	-1.1
Diabetes diagnosed by doctor	0.5	0.8	1.7	-0.3	1.3	0.7
Wears glasses or contact lenses	0.5	0.6	0.6	0.8	0.8	0.7
Medication: Bendroflumethiazide	0.5	0.7	1.1	-1.1	-0.2	-1.0
Leg fat percentage (left)	0.5	1.7	2.6	-1.6	-0.8	-1.4
Neuroticism (Nagel 2018)	0.4	1.0	1.4	0.9	-1.2	-0.8
Alzheimer’s Disease (in father)	0.4	0.4	0.5	0.7	0.4	0.7
Crohns Disease (2012)	0.4	0.6	0.9	0.2	0.9	1.0
Fasting Glucose	0.4	0.5	0.6	-0.6	0.8	0.7
LDL Cholesterol	0.4	0.7	1.3	-0.2	-0.8	-1.1
Neuroticism	0.4	1.0	1.4	1.1	-1.2	-0.7
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.2	-0.2	-1.1	-0.7
Hearing difficulty/problems: Yes	0.4	0.6	1.1	-0.3	-1.1	-0.7
Medication for hormone replacement therapy	0.4	0.4	0.6	0.5	0.8	0.6
Diabetes (father)	0.4	0.5	0.7	-0.8	-0.5	-0.8
Supplements: Glucosamine	0.4	0.5	0.7	-0.6	-0.7	-0.8
Pulse wave Arterial Stiffness index	0.4	0.4	1.2	-1.1	0.2	-0.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.1	-0.5	1.1	0.4
Leg fat percentage (right)	0.4	1.5	2.6	-1.6	-0.6	-1.2
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.6	0.6	0.7	0.8
Suffer from ‘nerves’	0.4	0.6	1.6	1.2	-0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.9	0.8	-0.9	-0.4
Medication: Aspirin	0.4	0.6	1.1	-1.1	0.1	-0.8
Supplements: Vitamin C	0.4	0.5	0.8	-0.8	-0.3	-0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.7	0.5	0.8	0.8
Medication: Aspirin	0.4	0.6	0.9	-1.0	0.0	-0.8
Arm fat-free mass (left)	0.4	1.9	3.2	-0.9	1.8	1.3
Age started oral contraceptive pill	0.4	0.4	0.8	0.2	-0.7	-0.9
Bipolar Disorder (2018)	0.3	0.5	1.0	-0.4	-0.6	-1.0
Depression (Nagel 2018)	0.3	0.4	0.6	-0.8	-0.6	-0.5
Coronary Artery Disease (CAD)	0.3	0.3	0.5	0.4	-0.5	-0.7
Lung FEV1/FVC ratio	0.3	1.5	2.7	0.4	1.6	1.3
Hand grip strength (left)	0.3	0.8	1.5	-1.2	-0.6	-0.7
Average weekly spirits intake	0.3	0.3	0.5	0.3	0.6	0.7
Ever had hysterectomy (womb removed)	0.3	0.3	0.6	-0.8	-0.5	-0.3
Medication: Metformin	0.3	0.4	0.8	-0.9	0.5	0.0
Leg fat-free mass (left)	0.3	1.6	2.9	-0.5	1.7	1.3
Medication: Levothyroxine sodium	0.3	0.5	0.8	0.0	0.9	0.8
Leg predicted mass (left)	0.3	1.6	3.0	-0.5	1.7	1.3
Neuroticism score	0.3	0.6	0.9	1.0	-0.8	-0.5
Arm fat percentage (right)	0.3	1.0	2.5	-1.6	-0.3	-0.7
Tense / ‘highly strung’	0.3	0.5	0.7	0.5	-0.8	-0.8
Headache pain in last month	0.3	0.6	0.9	1.0	0.2	0.9
Arm fat-free mass (right)	0.3	1.5	2.8	-0.6	1.7	1.2
Exposure to tobacco smoke outside home	0.3	0.4	0.6	-0.8	0.8	0.1
Worry too long after embarrassment	0.3	0.5	1.4	1.2	-0.4	0.0
Arm predicted mass (right)	0.3	1.4	2.5	-0.8	1.6	1.0
Whole body fat-free mass	0.3	1.5	2.7	-0.8	1.6	1.2
Leg fat-free mass (right)	0.3	1.7	3.1	-0.5	1.8	1.3
Whole body water mass	0.3	1.5	2.5	-0.8	1.6	1.2
Leg predicted mass (right)	0.3	1.7	3.3	-0.5	1.8	1.3
Basal metabolic rate	0.3	1.4	2.3	-1.0	1.5	1.0
Heart disease (siblings)	0.3	0.4	0.7	-0.1	-0.7	-0.8
Arm predicted mass (left)	0.3	1.4	1.9	-1.3	1.4	0.9
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	0.8	-0.4	0.2
Breast Cancer	0.2	0.6	1.0	0.5	1.0	0.7
Ovarian Cancer	0.2	0.2	0.4	0.4	0.6	0.4
Prostate Cancer	0.2	0.2	0.4	0.2	-0.4	-0.7
HDL Cholesterol	0.2	0.3	0.6	0.8	-0.6	-0.1
Neuroticism (2016)	0.2	0.3	0.8	0.9	0.2	-0.1
Hand grip strength (right)	0.2	0.4	0.6	-0.5	-0.8	-0.6
Maternal smoking around birth	0.2	0.3	0.6	0.8	0.4	0.5
Body mass index (BMI)	0.2	0.7	1.7	-1.3	-0.1	-0.6
Had menopause	0.2	0.3	0.6	-0.8	-0.2	-0.4
Had other major operations	0.2	0.2	0.5	0.7	0.4	0.2
Allergy	0.2	0.5	0.7	0.7	0.8	0.4
Trunk fat-free mass	0.2	1.3	2.0	-0.9	1.4	1.0
Time employed in main current job	0.2	0.2	0.2	0.5	0.5	0.4
Trunk predicted mass	0.2	1.4	2.2	-0.9	1.5	1.1
Standing height	0.2	2.4	3.8	0.3	1.9	1.8
Pulse wave reflection index	0.2	0.3	0.7	-0.8	0.2	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.4	-0.1	0.6	0.6
Medication: Paracetamol	0.2	0.3	0.5	0.5	-0.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.6	0.2	0.6	0.7
Body fat percentage	0.2	0.8	1.9	-1.4	-0.1	-0.7
Neck or shoulder pain in last month	0.2	0.2	0.4	-0.5	-0.7	-0.2
Migraine (self-reported)	0.2	0.2	0.3	0.4	0.5	0.4
Whole body fat mass	0.2	0.7	1.8	-1.4	0.2	-0.3
Leg fat mass (right)	0.2	0.9	2.2	-1.5	-0.2	-0.7
Illnesses of siblings: Diabetes	0.2	0.3	0.5	0.3	0.7	0.5
Loneliness, isolation	0.2	0.2	0.3	-0.5	0.4	0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.9	0.9	-0.3	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.3	0.6	0.2	0.6
Guilty feelings	0.2	0.4	0.7	0.4	-0.8	-0.5
Mother’s age at death	0.2	0.3	0.8	0.1	-0.9	-0.2
Alcohol drinker status: Never	0.2	0.2	0.4	0.6	-0.5	-0.3
Irritability	0.2	0.3	0.5	0.7	0.5	0.1
Risk taking	0.2	0.3	0.4	0.5	0.3	0.6
Pain experienced in last month	0.2	0.4	0.6	-0.8	0.6	-0.4
Supplements: Calcium	0.2	0.2	0.5	0.1	-0.7	-0.4
Leg fat mass (left)	0.2	0.9	2.3	-1.5	-0.1	-0.7
Crohns Disease (2017)	0.1	0.3	0.5	0.7	0.4	0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	0.6	-0.6	-0.4
HbA1C	0.1	0.1	0.2	0.4	-0.4	-0.1
Lupus	0.1	0.1	0.2	-0.1	-0.4	-0.4
Ulcerative Colitis	0.1	0.2	0.4	0.7	-0.2	0.0
Blood Platelet Count	0.1	0.7	1.2	0.3	-1.1	-0.9
Blood Red Count	0.1	1.4	2.6	0.8	1.6	0.9
Height	0.1	2.0	3.2	0.0	1.8	1.7
Hair Pigment	0.1	2.6	3.3	-1.2	-1.8	-1.7
Tanning	0.1	1.6	3.4	0.1	1.9	1.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	-0.5	-0.0	0.2
Impedance of leg (right)	0.1	0.7	0.9	-0.6	-1.0	-0.8
Trunk fat percentage	0.1	0.5	1.5	-1.2	0.1	-0.4
Age when periods started (menarche)	0.1	0.2	0.3	0.3	0.4	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.5	-0.7	-0.1	0.1
Multivitamins +/- minerals	0.1	0.2	0.4	-0.2	0.6	-0.3
Sitting height	0.1	0.5	0.7	-0.6	0.8	0.8
Impedance of leg (left)	0.1	0.6	0.9	-0.5	-0.9	-0.9
Trunk fat mass	0.1	0.6	1.5	-1.2	0.5	-0.0
Waist circumference	0.1	0.3	0.7	-0.8	-0.0	-0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.3	0.2	-0.6	0.0
Diabetes (self-reported)	0.1	0.1	0.2	-0.4	0.2	0.1
Weight	0.1	0.7	1.0	-1.0	0.9	0.4
Hip circumference	0.1	0.4	0.8	-0.3	0.9	0.6
Falls in the last year	0.1	0.1	0.3	-0.5	-0.1	-0.3
Number of live births	0.1	0.1	0.3	-0.2	0.0	0.6
Noisy workplace	0.1	0.1	0.1	0.3	-0.4	-0.3
Impedance of arm (left)	0.1	0.4	1.0	1.0	-0.0	0.3
Arm fat mass (right)	0.1	0.4	1.1	-1.1	0.4	0.0
Gout (self-reported)	0.1	0.2	0.6	-0.8	0.1	-0.0
Birth weight	0.1	0.3	0.7	0.8	-0.3	0.0
Number of children fathered	0.1	0.1	0.2	-0.5	0.2	0.3
Shortness of breath walking on level ground	0.1	0.1	0.1	0.2	-0.4	-0.2
Comparative height size at age 10	0.1	0.3	0.8	-0.9	0.2	-0.1
Family relationship satisfaction	0.1	0.2	0.3	0.5	-0.1	0.5
Leg pain on walking	0.1	0.1	0.3	0.0	-0.5	-0.3
Knee pain experienced in last month	0.1	0.2	0.3	0.1	0.6	0.4
Arm fat percentage (left)	0.1	0.6	1.5	-1.2	-0.1	-0.5
Medication for cholesterol	0.1	0.1	0.2	0.4	0.2	0.5
Breast cancer (self-reported)	0.1	0.1	0.2	-0.3	-0.4	-0.4
Osteoporosis (self-reported)	0.1	0.1	0.2	0.5	0.2	0.2
Arm fat mass (left)	0.1	0.5	1.0	-1.0	0.6	0.2
Financial situation satisfaction	0.1	0.1	0.3	0.1	-0.5	-0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	0.4	-0.2	0.3
Medication: Paracetamol	0.1	0.1	0.1	0.3	-0.4	-0.2
Illnesses of father: High blood pressure	0.1	0.1	0.2	-0.3	0.4	0.2
Average weekly beer plus cider intake	0.1	0.1	0.2	-0.2	0.5	0.3
Fractured/broken bones in last 5 years	0.1	0.2	0.3	0.3	0.6	0.4
Cholesterol lowering medication	0.1	0.2	0.3	0.5	-0.2	-0.5
Alcohol drinker status: Previous	0.1	0.1	0.3	0.1	-0.6	-0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	0.1	-0.3	-0.2
Rheumatoid Arthritis	0.0	0.1	0.1	-0.0	-0.3	-0.3
Blood Eosinophil Count	0.0	0.0	0.1	-0.2	0.3	0.1
Heel T-Score	0.0	0.3	0.9	0.9	0.4	-0.0
BMI	0.0	0.2	0.5	-0.7	0.1	-0.3
Waist Hip Ratio (WHR)	0.0	0.1	0.2	0.5	0.3	0.3
Allergy or Eczema	0.0	0.0	0.1	0.1	-0.0	0.3
Hypothyroidism (self reported)	0.0	0.1	0.1	-0.3	0.2	0.3
Lung FVC	0.0	0.2	0.4	-0.6	0.6	-0.0
Pack years adult smoking proportion	0.0	0.0	0.1	-0.2	-0.1	-0.2
Townsend deprivation index at recruitment	0.0	0.0	0.0	-0.1	0.2	0.0
Relative age voice broke	0.0	0.1	0.1	0.3	-0.3	-0.1
Bilateral oophorectomy (both ovaries removed)	0.0	0.1	0.1	-0.1	-0.3	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.1	-0.1	-0.2	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	-0.1	-0.2	-0.2
Impedance of arm (right)	0.0	0.1	0.2	0.3	-0.5	-0.1
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	0.3	0.1	-0.1
Illnesses of mother	0.0	0.1	0.1	0.2	0.1	0.3
Hair/balding pattern: Pattern 4	0.0	0.0	0.1	0.0	0.0	0.3
Had major operations	0.0	0.0	0.1	0.3	0.0	-0.0
Miserableness	0.0	0.0	0.0	0.1	-0.1	-0.1
Pack years of smoking	0.0	0.1	0.1	-0.2	-0.2	-0.3
Impedance of whole body	0.0	0.1	0.2	0.4	-0.5	-0.2

Hub : Genes

C2orf7

Models

Trait associations